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    1069 results match your criteria Urticarial Vasculitis

    1 OF 22
    [Urticaria multiforme: difficult to distinguish from other skin conditions].
    Ned Tijdschr Geneeskd 2018 ;162(0):D2251
    Westfriesgasthuis, afd. Kindergeneeskunde en Neonatologie, Hoorn.
    Background: Urticaria multiforme is a rare clinical variant of urticaria that occurs specifically in children.

    Case Description: A boy aged 11 months was presented at the Emergency Department with acute onset of itching urticarial skin weals and acral oedema. This picture is consistent with the diagnosis of urticaria multiforme. Read More
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    Role of Direct Immunofluorescence in Cutaneous Small-Vessel Vasculitis: Experience From a Tertiary Center.
    Am J Dermatopathol 2018 Apr 17. Epub 2018 Apr 17.
    Departments of Histopathology.
    Skin is commonly affected by vasculitic process and often subjected to biopsy. Cutaneous vasculitis can be either primary or part of a systemic vasculitic process. This study was conducted to evaluate the diagnostic utility of direct immunofluorescence (DIF) in determination of etiology of cutaneous vasculitis. Read More
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    A Case of Crescentic Glomerulonephritis Complicated with Hypocomplementemic Urticarial Vasculitis Syndrome and ANCA-Associated Vasculitis.
    Case Rep Nephrol Dial 2017 Sep-Dec;7(3):144-153. Epub 2017 Nov 27.
    Department of Cardiovascular, Renal and Metabolic Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
    Systemic urticaria in a 64-year-old woman was diagnosed as leukocytoclastic vasculitis by a punch biopsy of the skin. Her physical findings improved after prescription of prednisolone at a dose of 20 mg/day, but the skin rash relapsed with renal dysfunction, proteinuria, and hematuria when the dose of prednisolone was reduced over a period of 9 months to 1 mg/day. She was admitted to our institute for further examination, when urinary protein and plasma creatinine levels were 0. Read More
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    Acute respiratory distress syndrome in a man with Epstein-Barr virus infection-induced hypocomplementemic urticarial vasculitis.
    J Formos Med Assoc 2018 May 16;117(5):452-453. Epub 2018 Feb 16.
    Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, 7F, No. 325, Section 2, Cheng-Kung Road, Neihu District 114, Taipei City, Taiwan.
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    Colchicine in dermatology: A review.
    Australas J Dermatol 2018 Feb 12. Epub 2018 Feb 12.
    Department of Dermatology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
    Colchicine is an anti-inflammatory agent that has been used for decades for the treatment of various diseases including gout, familial Mediterranean fever and pericarditis and in recent years for dermatological indications including chronic urticaria, cutaneous vasculitis and psoriasis. Despite its efficacy in various cutaneous diseases, the use of colchicine may be limited by concerns over its side-effects and the potential for toxicity. This article reviews the current literature on the pharmacology of colchicine and its clinical applications in dermatology. Read More
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    Hypocomplementemic Urticarial Vasculitis Syndrome With Crescentic Glomerulonephritis.
    Am J Med Sci 2018 Feb 8;355(2):195-200. Epub 2017 Apr 8.
    Department of Internal Medicine, University of Mississippi Medical Center, Jackson, Mississippi.
    Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a rare autoimmune disease characterized by multiple organ system involvement, including renal disease, with low complement levels. We report the case of a 31-year-old woman who presented with nonspecific symptoms including fatigue, diarrhea, macular rash and abdominal pain with acute renal failure leading to end-stage kidney disease. Laboratory results showed hematuria, nephrotic range proteinuria, worsening creatinine and low C1q levels. Read More
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    [Dermatological features of auto-inflammatory recurrent fevers].
    Arch Pediatr 2018 Feb 1;25(2):150-162. Epub 2018 Feb 1.
    Université Paris-Saclay, university Paris-Sud, CHU de Bicêtre, 78, avenue du Général-Leclerc, Le-Kremlin-Bicêtre, France.
    Auto-inflammatory diseases are characterized by unexplained and recurrent attacks of systemic inflammation often involving the skin, joints, or serosal membranes. They are due to a dysfunction or dysregulation of the innate immunity, which is the first line of defense against pathogens. Early recognition of these diseases by the clinician, especially by pediatricians encountering such pathologies in pediatric patients, is primordial to avoid complications. Read More
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    Cutaneous and systemic vasculitides in dermatology: a histological perspective.
    G Ital Dermatol Venereol 2018 Apr 24;153(2):185-193. Epub 2018 Jan 24.
    Unit of Dermatology, IRCCS Ca' Granda Foundation, Ospedale Maggiore Policlinico, Milan, Italy.
    Cutaneous vasculitides encompass a wide and heterogeneous group of diseases affecting skin blood vessels that are clinically characterized by polymorphic skin lesions, particularly including palpable purpura as well as urticarial and necrotic-ulcerative lesions, with possible, albeit rare, extracutaneous involvement. Cutaneous leukocytoclastic angiitis and urticarial vasculitis, which are the two prototypic and most common variants of this group, are usually idiopathic but may also be induced by different triggers, notably drugs and infections, or may manifest in association with systemic disorders, particularly lupus erythematosus. Vasculitis skin lesions can also occur during the chronic-relapsing course of systemic vasculitides, such as granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis, with which cutaneous vasculitides can share clinical and histological features. Read More
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    Cutis Laxa Acquisita After Urticarial Vasculitis in SLE Patients.
    Am J Dermatopathol 2018 Jan 11. Epub 2018 Jan 11.
    Division of Dermatopathology, Department of Medicine, University of Arizona, Tucson, AZ.
    Cutis laxa is a rare connective tissue disease involving damage to dermal elastic fibers creating a clinical appearance of loose, sagging skin. The condition can be either acquired or genetic. Autoimmune diseases, neoplasms, infections, and medications have been proposed as the cause of, or in association with, the acquired form. Read More
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    Etiology of chronic urticaria: the Ecuadorian experience.
    World Allergy Organ J 2018 3;11(1). Epub 2018 Jan 3.
    Universidad Espíritu Santo, Km. 2.5 vía La Puntilla, Código postal: 0901-952 Samborondón, Ecuador.
    Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its treatment.

    Methods: We performed a retrospective study involving 112 patients diagnosed with CU using a Checklist for a complete chronic urticaria medical history. Read More
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    [Humoral immune diseases: Cutaneous vasculitis and auto-immune bullous dermatoses].
    Ann Pathol 2018 Feb 27;38(1):31-42. Epub 2017 Dec 27.
    Département de pathologie, service d'anatomie et de cytologie pathologiques, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France. Electronic address:
    Humoral immunity is the cause of multiple diseases related to antibodies (IgA, IgG, IgM) produced by the patient. Two groups of diseases are identified. The first group is related to circulating antigen-antibody complexes. Read More
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    Deferasirox-induced urticarial vasculitis in a patient with myelodysplastic syndrome.
    An Bras Dermatol 2017 ;92(5 Suppl 1):59-61
    Department of Pathology, Mugla Sitki Kocman University, Faculty of Medicine - Mugla, Turkey.
    Deferasirox is an iron chelator agent used in the treatment of diseases with iron overload, such as thalassemia and myelodysplastic syndrome. Although the majority of adverse reactions of deferasirox involve gastrointestinal symptoms and increase in serum creatinine and transaminases, skin rashes, such as maculopapular and urticarial eruptions, have also been reported. This study reports a case of myelodysplastic syndrome with urticarial vasculitis due to deferasirox therapy. Read More
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    Lymphocytes in Sweet syndrome: A potential diagnostic pitfall.
    J Cutan Pathol 2018 Mar 23;45(3):217-222. Epub 2018 Jan 23.
    Ackerman Academy of Dermatopathology, New York, New York.
    Background: Patients with Sweet syndrome (SS) have acute onset of cutaneous lesions with characteristic histopathology (dense and diffuse neutrophilic infiltrate, dermal edema, leukocytoclasis and no vasculitis) accompanied by systemic symptoms. Sometimes, only skin lesions with classic histopathologic features are seen. Although SS is considered to be a "neutrophilic dermatosis," lymphocytes are also seen on histological examination. Read More
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    Bullous Pemphigoid Masquerading as Erythema Annulare Centrifugum.
    Acta Dermatovenerol Croat 2017 Oct;25(3):255-256
    Sheng-Yiao Lin, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan;
    Dear Editor, Bullous pemphigoid (BP), a relatively common autoimmune blistering disease in the elderly, is characterized by large, tense bullae on urticarial, erythematous, or normal skin. However, atypical BP with polymorphic clinical presentations is rarely encountered, leading to misdiagnosis and delayed treatments (1). BP with lesions resembling erythema gyratum repens or figurate erythema has been regarded as a paraneoplastic phenomenon (1). Read More
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    Urticarial vasculitis after meningococcal serogroup B vaccine in a 6-year-old girl.
    Pediatr Dermatol 2018 Jan 21;35(1):e64-e65. Epub 2017 Nov 21.
    Department of Dermatology, Hospital 12 de Octubre, Madrid, Spain.
    The first vaccine that shows significant potential in providing broad coverage against serogroup B meningococcal disease has recently been approved. Because of its newness, potential adverse events need to be reported. Here we report a case of urticarial vasculitis, a rare disease in children, in probable relationship with the novel vaccine. Read More
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    Hypocomplementemic Urticarial Vasculitis Syndrome with Membranous Nephropathy: Case Report.
    J Korean Med Sci 2017 Dec;32(12):2064-2068
    Division of Rheumatology, Department of Internal Medicine, Kyung Hee University Medical Center, Seoul, Korea.
    Urticarial vasculitis is a rare disorder that principally manifests with recurrent urticarial, sometimes hemorrhagic, skin lesions and/or angioedema. Its clinical presentation is not always limited to cutaneous lesions and it can potentially affect other organs, such as the joints, lungs, kidneys, and eyes. Systemic involvement can either be present at the onset of disease or develop over time. Read More
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    Clinical utility of anti-C1q antibody in primary and secondary vasculitic conditions.
    Int J Health Sci (Qassim) 2017 Nov-Dec;11(5):3-6
    Department of Clinical Immunology & Rheumatology, Christian Medical College, Vellore, Tamil Nadu, India.
    Objective: Anti-C1q antibodies (Anti-C1q Ab) are seen in hypocomplementemic urticarial vasculitis syndrome (HUVS), infection-associated vasculitis such as hepatitis C virus-related vasculitis and in autoimmune diseases such as rheumatoid vasculitis, polyarteritis nodosa, giant cell arteritis, vascular Behcet's disease, and cryoglobulin associated vasculitis. Aim of this study is to evaluate the presence of Anti-C1q Ab in vasculitis and to determine if any difference exists between primary and secondary vasculitis in relation to this antibody.

    Patients And Methods: Consecutive patients with diagnosis of either a primary or secondary vasculitis were recruited. Read More
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    Autoantibodies against complement components in systemic lupus erythematosus - role in the pathogenesis and clinical manifestations.
    Lupus 2017 Dec 18;26(14):1550-1555. Epub 2017 May 18.
    2 Department of Chemistry, Biochemistry, Physiology and Pathophysiology, Sofia University "St. Kliment Ohridski", Bulgaria.
    Many complement structures and a number of additional factors, i.e. autoantibodies, receptors, hormones and cytokines, are implicated in the complex pathogenesis of systemic lupus erythematosus. Read More
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    [Acute hemorrhagic edema of infancy: alarming lesions of a benign condition. Case report].
    Arch Argent Pediatr 2017 12;115(6):e432-e435
    Salud total EPS, Urbanización El Bosque.
    We report a case of acute hemorrhagic edema of infancy in an 18-month-old boy after an episode of otitis media. The clinical presentation begins with skin erythematous macules on the thighs, followed by purpuric lesions in arms, legs, and ankle edema. It was initially interpreted as urticaria, whereby steroids were indicated. Read More
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    Pediatric vasculitis: a single center experience.
    Int J Dermatol 2017 Nov 19;56(11):1130-1138. Epub 2017 Sep 19.
    First Department of Pediatrics, University of Athens, Aghia Sofia Children's Hospital, Athens, Greece.
    Background: Existing studies of children with vasculitis are limited. The aim of this study was to assess the epidemiology, clinical manifestations, laboratory findings, course, and outcome of Greek children presenting with vasculitic rash.

    Methods: The relevant data included in the study were collected retrospectively using a standardized form from children who were admitted into our department between 2003 and 2013, with the provisional diagnosis of vasculitis of the skin. Read More
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    Clinical and pathological significance of cutaneous manifestations in ANCA-associated vasculitides.
    Autoimmun Rev 2017 Nov 14;16(11):1138-1146. Epub 2017 Sep 14.
    Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France; Faculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, Paris, France. Electronic address:
    Objectives: Cutaneous manifestations (CM) in ANCA-associated vasculitides (AAV) are frequent, but data on clinical significance and clinical-pathological correlations are lacking.

    Methods: We conducted a multicenter, retrospective study including 1553 AAV patients. Clinical, biological and pathological features have been analyzed, and tissue samples from 46 biopsies were reviewed in a blind manner. Read More
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    Recurrence of Chronic Urticaria: Incidence and Associated Factors.
    J Allergy Clin Immunol Pract 2018 Mar - Apr;6(2):582-585. Epub 2017 Sep 6.
    Department of Internal Medicine, Division of Allergy & Immunology, University of Texas Southwestern Medical Center, Dallas, Tex. Electronic address:
    Background: Chronic urticaria (CU) is urticaria that has been present continuously or intermittently for at least 6 weeks. Although the prevalence and characteristics of CU are well established, little is known about recurrent CU (RCU).

    Objectives: We sought to establish a definition, determine the frequency, and evaluate risk factors for RCU. Read More
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    The Histopathology of Urticaria Revisited-Clinical Pathological Study.
    Am J Dermatopathol 2017 Oct;39(10):753-759
    *Department of Dermatology, Sheba Medical Center, Tel-Hashomer, Israel; and †Institute of Pathology, Sheba Medical Center, Tel Hashomer, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
    Background: The classic histopathological findings of urticaria include dermal edema and a sparse perivascular infiltrate of neutrophils, eosinophils, macrophages, and lymphocytes. However, this pattern is inconsistently described.

    Objective: To describe the histological and immunofluorescence characteristics of urticaria and to identify distinctive patterns. Read More
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    Cutaneous Manifestations of Small-Vessel Leukocytoclastic Vasculitides in Childhood.
    Clin Rev Allergy Immunol 2017 Dec;53(3):439-451
    Pediatric Department of Southern Switzerland, San Giovanni Hospital, 6500, Bellinzona, Switzerland.
    In childhood, cutaneous small-vessel vasculitides include Henoch-Schönlein syndrome, a systemic vasculitis, and Finkelstein-Seidlmayer syndrome, a skin-limited vasculitis. Both Henoch-Schönlein and Finkelstein-Seidlmayer syndromes are seen more frequently in white or Asian compared with black children and occur especially in winter and spring with a male-to-female ratio of approximately 2:1. In everyday clinical practice, both conditions are diagnosed on clinical grounds without histological confirmation. Read More
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    Urticaria vasculitis in a child: a case report and literature review.
    Clin Case Rep 2017 Aug 21;5(8):1255-1257. Epub 2017 Jun 21.
    Department of DermatologyHospital Universitario Severo OchoaAvenida de Orellana28911LeganésMadridSpain.
    Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness. Read More
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    Jaccoud's arthropathy, an unusual manifestation of idiopathic retroperitoneal fibrosis: rapid improvement of symptoms after tocilizumab treatment.
    Reumatismo 2017 Aug 3;69(2):88-91. Epub 2017 Aug 3.
    Rheumatology Unit, San Giovanni di Dio Hospital, Florence.
    Jaccoud's arthropathy (JA) is a chronic, non erosive, rheumatoid-like deformity associated with rheumatic fever (RF) and systemic lupus erythematosus and with other diseases such as psoriatic arthritis, connective tissue diseases, hypocomplementemic urticarial vasculitis, infections, sarcoidosis and neoplasia. We described a case of JA in a patient with cutaneous psoriasis but with a particular disease evolution associated with idiopathic retropritoneal fibrosis (IRF), evaluated with computed tomography, magnetic resonance and 18F-FDG PET/ CT. The patient, following failure with steroids, methotrexate and etanercept, was treated with tocilizumab (8 mg/kg) once every 4 weeks for 6 months. Read More
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    Renal manifestations in hypocomplementic urticarial vasculitis syndrome: Is it a distinct pathology?
    Saudi J Kidney Dis Transpl 2017 Jul-Aug;28(4):929-933
    Department of Pediatrics, Salmaniya Medical Complex, Manama, Kingdom of Bahrain.
    Hypocomplementic urticarial vasculitis syndrome (HUVS) is an autoimmune disease characterized by recurrent urticaria, arthritis, and glomerulonephritis (GN). Anti-C1q antibody is the marker of HUVS together with low levels of classical pathway complements which are C2, C3, C4, and C1q. We report a case of a 6-year-old boy who presented with episodes of rashes, injected conjunctiva, abdominal pain, and arthritis, diagnosed as HUVS. Read More
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    Making Sense of Metal Allergy and Hypersensitivity to Metallic Implants in Relation to Hand Surgery.
    J Hand Surg Am 2017 Sep 12;42(9):737-746. Epub 2017 Jul 12.
    Department of Orthopedic Surgery, Division of Hand Surgery, Mayo Clinic, Rochester, MN. Electronic address:
    All metals implanted into a biological system undergo some degree of corrosion depending upon its composition. The electrochemical process of corrosion produces free metal ions, which may activate the host's immune system through a variety of mechanisms. Whereas dermal metal hypersensitivity is common, affecting 10% to 15% of the population, the immune reaction from implanted metals is much less common (< 0. Read More
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    Possible role of Helicobacter pylori in diseases of dermatological interest.
    J Biol Regul Homeost Agents 2017 APR-JUN;31(2 Suppl. 2):57-77
    Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
    Helicobacter pylori is a gram-negative, flagellate, microaerophilic bacterium identified for the first time about 30 years ago, as a pathogenic factor of gastritis and peptic ulcer. Soon after, it was linked to several gastrointestinal and extra-gastrointestinal diseases (hematological, cardiovascular, neurological, pulmonary and ocular diseases, obesity, diabetes mellitus, growth retardation and extragastric MALT lymphoma). Association and possible cause-effect correlation with H. Read More
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    Erythema Gyratum Repens-Like Purpura in a Patient with Sjögren Syndrome.
    Case Rep Dermatol 2017 May-Aug;9(2):40-43. Epub 2017 Jun 14.
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    The etiology of purpura in Sjögren syndrome (SS) includes cryoglobulinemia, hypergammaglobulinemia, and leukocytoclastic vasculitis (LCV). The clinical symptoms of LCV associated with SS comprise palpable or nonpalpable purpura and urticarial vasculitis. Here, we report a case of LCV presenting as erythema gyratum repens (EGR)-like purpura in a 62-year-old woman with rheumatoid arthritis and SS. Read More
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    Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial.
    NPJ Parkinsons Dis 2017 23;3:10. Epub 2017 Mar 23.
    Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE USA.
    A potential therapeutic role for immune transformation in Parkinson's disease evolves from more than a decade of animal investigations demonstrating regulatory T cell (Treg) nigrostriatal neuroprotection. To bridge these results to human disease, we conducted a randomized, placebo-controlled double-blind phase 1 trial with a well-studied immune modulator, sargramostim (granulocyte-macrophage colony-stimulating factor). We enrolled 17 age-matched non-Parkinsonian subjects as non-treated controls and 20 Parkinson's disease patients. Read More
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    [Hypocomplementemic urticarial vasculitis].
    Rev Med Interne 2018 Feb 28;39(2):90-98. Epub 2017 Apr 28.
    Service de médecine interne, faculté de médecine, centre de référence national pour les maladies auto-immunes et systémiques rares, en particulier les vascularites systémiques, hôpital Cochin, université Paris-Descartes, Assistance publique-Hôpitaux de Paris, 75014 Paris, France. Electronic address:
    Hypocomplementemic urticarial vasculitis (HUV), called anti-C1q vasculitis in the 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides, is a rare systemic vasculitis of unknown etiology, affecting small vessels. HUV is characterized by urticarial lesions, hypocomplementemia and systemic manifestations, mostly musculoskeletal and ocular, but also gastrointestinal, pulmonary and kidney involvement. Anti-C1q antibodies are detected in only half of the patients, and low C1q seems to represent a more sensitive marker. Read More
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    Imatinib mesylate-induced lichenoid drug eruption.
    Cutis 2017 Mar;99(3):189-192
    Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, USA.
    Imatinib mesylate (imatinib) is a tyrosine kinase inhibitor initially approved by the US Food and Drug Administration in 2001 for chronic myeloid leukemia (CML). Since then, the number of indicated uses for imatinib has substantially increased. It is increasingly important that dermatologists recognize adverse cutaneous manifestations of imatinib and are aware of their management and outcomes to avoid unnecessarily discontinuing a potentially lifesaving medication. Read More
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    Clinical study on single-organ cutaneous small vessels vasculitis (SoCSVV).
    Medicine (Baltimore) 2017 Mar;96(12):e6376
    aDepartment of Dermatology b2nd Department of Medicine, Jagiellonian University Medical College, Cracow, Poland.
    Leukocytoclastic vasculitis (LCV) is a heterogenous group of disorders that may manifest as a mild disease isolated to the skin or be a part of life-threatening systemic vasculitis. According to the 2012 Chapel Hill Consensus Conference nomenclature, patients presenting symptoms of LCV confined only to the skin should be defined as suffering from a single-organ cutaneous small vessel vasculitis (SoCSVV). SoCSVV is a benign disease with a good clinical outcome but with a significant risk of relapse and skin ulcer formation. Read More
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    Effectiveness of omalizumab in a case of urticarial vasculitis.
    Clin Exp Dermatol 2017 Mar 1. Epub 2017 Mar 1.
    Department of Dermatology, Hospital Clinico Universitario San Carlos, Madrid, Spain.
    Urticarial vasculitis (UV) is a mainly leucocytoclastic vasculitis with urticarial plaques. Treating these patients is challenging as the available treatments have poor efficacy. Oral corticosteroids are considered the first-line treatment, but H1 antihistamines, dapsone, colchicine, antimalarials, ciclosporin and antileucotrienes have all been tried also. Read More
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    Common Skin Conditions in Children: Noninfectious Rashes.
    FP Essent 2017 Feb;453:18-25
    University of North Carolina Chapel Hill School of Medicine Dermatology Residency Program, 410 Market St. Suite 400 CB#7715, Chapel Hill, NC 27516.
    Cutaneous adverse drug reactions are among the most common noninfectious rashes of childhood. Cutaneous adverse drug reactions are classified as morbilliform, urticarial, bullous, pustular, or psoriasiform. Atopic dermatitis is one of the most common inflammatory cutaneous eruptions, and is characterized by pruritus and flexural distribution. Read More
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    [Severe pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV)].
    Pan Afr Med J 2016 28;24:285. Epub 2016 Jul 28.
    Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc.
    Pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV) or Mac Duffie syndrome is extremely rare with a poor prognosis. We report the case of a 55-year-old female patient treated for HUV over a period of 20 years. The diagnosis was confirmed on the basis of urticarial lesions, ocular inflammation, positive C1q-p test by immunodiffusion, with low rate of C1q. Read More
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    Disorders characterized by predominant or exclusive dermal inflammation.
    Semin Diagn Pathol 2017 May 14;34(3):273-284. Epub 2016 Dec 14.
    Section of Dermatopathology, Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, Room 3020 University of Virginia Hospital, 1215 Lee Street, Charlottesville, VA 22908-0214, USA. Electronic address:
    Some cutaneous inflammatory disorders are typified by a predominant or exclusive localization in the dermis. They can be further subdivided by the principal cell types into lymphocytic, neutrophilic, and eosinophilic infiltrates, and mixtures of them are also seen in a proportion of cases. This review considers such conditions. Read More
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    Management of chronic spontaneous urticaria in routine clinical practice: A Delphi-method questionnaire among specialists to test agreement with current European guidelines statements.
    Allergol Immunopathol (Madr) 2017 Mar - Apr;45(2):134-144. Epub 2016 Oct 28.
    Pneumology and Allergy Service, Hospital Clinic (ICT), University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) [August Pi i Sunyer Biomedical Research Institute], Barcelona, Spain.
    Background: Chronic spontaneous urticaria (CSU) is a frequent clinical entity that often presents a diagnostic and therapeutic challenge.

    Objective: To explore the degree of agreement that exists among the experts caring for patients with CSU diagnosis, evaluation, and management.

    Methods: An online survey was conducted to explore the opinions of experts in CSU, address controversial issues, and provide recommendations regarding its definition, natural history, diagnosis, and treatment. Read More
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    Acrally distributed dermatoses: Vascular dermatoses (purpura and vasculitis).
    Clin Dermatol 2017 Jan - Feb;35(1):68-80. Epub 2016 Sep 10.
    Department of Dermatology and Venereology, Tokuda Hospital Sofia, Sofia, Bulgaria.
    Purpuric lesions appear in acral distribution in a variety of conditions and often provide clues to the clinical diagnosis. Purpuric means "hemorrhagic"-that is, the lesions do not blanch from pressure. This review focuses on dermatoses that produce hemorrhagic lesions in acral distribution from the large groups of the vasculitic diseases and their mimics. Read More
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    A case of urticarial vasculitis in a female patient with lupus: Mycoplasma pneumoniae infection or lupus reactivation?
    Rheumatol Int 2017 May 5;37(5):837-840. Epub 2016 Dec 5.
    Department of Woman, Child and of General and Specialized Surgery, Università della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
    A 17-year-old female patient affected by systemic lupus erythematosus (SLE) (who had been taking 300 mg/die of hydroxychloroquine for 3 years), Graves' disease (treated with 10 mg/die of tapazole), and celiac disease came to our attention for urticarial vasculitis. She had been taking prednisone (25 mg/die) for 3 days, and her blood tests showed high levels of Mycoplasma pneumoniae IgM and IgG antibodies. The association between urticaria and M. Read More
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    Successful Re-administration of Low-dose of Methimazole (MMI) in Graves' Disease Patients Who Experienced Allergic Cutaneous Reactions to MMI at Initial Treatment and Had Received Long-term Propylthiouracil (PTU).
    Intern Med 2016;55(22):3235-3237. Epub 2016 Nov 15.
    Kubota Thyroid Clinic, Japan.
    Objective When patients with Graves' disease show severe allergic cutaneous reactions, physicians often suggest that they undergo radioiodine therapy instead of receiving propylthiouracil (PTU), another antithyroid drug, because anti-neutrophil cytoplasmic antibody (ANCA) -related vasculitis can occur with PTU, especially with long-term use. However, some patients refuse radioiodine therapy and chose PTU. Sometimes PTU treatment may be prolonged. Read More
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    Urticarial vasculitis in the childhood with C2 hypocomplementenemia: a rare case.
    Eur Ann Allergy Clin Immunol 2016 Nov;48(6):247-250
    Facultade de Medicina do ABC (FMABC), Santo André (SP), Brazil.
    We report a first case of hypocomplementemic urticarial vasculitis of C2 fraction in a child, with cutaneous manifestation only, with no reports in scientific literature. Read More
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    An autosomal recessive DNASE1L3-related autoimmune disease with unusual clinical presentation mimicking systemic lupus erythematosus.
    Lupus 2017 Jun 12;26(7):768-772. Epub 2016 Nov 12.
    1 Division of Rheumatology, Institute of Rheumatology, Catholic University School of Medicine, Rome, Italy.
    We describe the third family in the world, after Arabian and Turkish ones, displaying an autosomal recessive autoimmune disease (AID), mimicking systemic lupus erythematosus (SLE), with unusual manifestations due to a homozygous frame-shift variant in DNASE1L3. SLE is a complex AID characterized by multiple organ involvement. Genetic risk variants identified account for only 15% of SLE heritability. Read More
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