Search Our Scientific Publications & Authors

Acta Clin Croat 2021 Dec;60(4):711-721

1Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; 2School of Dental Medicine, University of Zagreb, Zagreb, Croatia; 3Unit of Dermatology and Venereology, Zabok General Hospital, Bračak/Zabok, Croatia; 4Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 5Ljudevit Jurak Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Although there are many single case reports on paraneoplastic dermatoses in the literature, there are very rare articles containing multiple cases. A retrospective study was performed to examine paraneoplastic dermatoses and accompanying malignancies based on skin manifestations and appropriate diagnostic evaluations. We recorded outcomes, current conditions, and surgical/oncologic treatments. Read More

Allergol Immunopathol (Madr) 2022 17;50(S Pt 1):17-29. Epub 2022 May 17.

Division of Pediatric Allergy and Clinical Immunology, Department of Pediatrics, McGill University Health Centre, Montreal, Canada.

Urticaria diagnosis may be challenging in children since it can be triggered or related to numerous conditions. In this paper, we reviewed the main aspects regarding the diagnosis of urticaria in the pediatric population. Acute urticaria is often due to viral infections. Read More

Dermatol Ther 2022 Jun 18:e15651. Epub 2022 Jun 18.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Various adverse effects particularly cutaneous manifestations associated with different COVID-19 vaccines have been observed in practice.

Aim: To evaluate all patients who presented to our tertiary center with skin manifestations following COVID-19 vaccines injection from September to December 2021.

Method: All patients with skin manifestation within 30 days or less following COVID-19 vaccination were enrolled in our case-series. Read More

J Clin Immunol 2022 Jun 7. Epub 2022 Jun 7.

The International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, UCBL, Lyon, France.

Background: Deoxyribonuclease 1 like 3 (DNASE1L3) is a secreted enzyme that has been shown to digest the extracellular chromatin derived from apoptotic bodies, and DNASE1L3 pathogenic variants have been associated with a lupus phenotype. It is unclear whether interferon signaling is sustained in DNASE1L3 deficiency in humans.

Objectives: To explore interferon signaling in DNASE1L3 deficient patients. Read More

JBJS Rev 2022 Jun 3;10(6). Epub 2022 Jun 3.

Serviço de Ortopedia e Traumatologia Prof. Nova Monteiro, Hospital Municipal Miguel Couto, Rio de Janeiro, Brazil.

»: COVID-19 is a disease that is challenging science, health-care systems, and humanity. An astonishingly wide spectrum of manifestations of multi-organ damage, including musculoskeletal, can be associated with SARS-CoV-2.

»: In the acute phase of COVID-19, fatigue, myalgia, and arthralgia are the most common musculoskeletal symptoms. Read More

Dermatol Ther 2022 Jun 2:e15613. Epub 2022 Jun 2.

Department of Dermatology, Kanazawa Medical University, Uchinada, Ishikawa, Japan.

J Eur Acad Dermatol Venereol 2022 May 23. Epub 2022 May 23.

Department of Dermatology, Fattouma Bourguiba University Hospital of Monastir, Monastir, Tunisia.

Int J Retina Vitreous 2022 May 20;8(1):31. Epub 2022 May 20.

Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, 1000 Wall St, Ann Arbor, MI, 48105, USA.

Background: Dapsone is a synthetic sulfonamide used to treat numerous dermatologic conditions. Ocular side effects have been rarely reported and include retinal necrosis, optic atrophy, and macular infarction. We report the first known case of bilateral choroidal effusions and exudative retinal detachments associated with dapsone use. Read More

CMAJ 2022 May;194(17):E612

Department of Dermatology (Hung, Chen), Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; Drug Hypersensitivity Clinical and Research Center (Hung, Chen), Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; College of Medicine (Hung, Chen), Chang Gung University, Taoyuan, Taiwan; Graduate Institute of Immunology (Chen), College of Medicine, National Taiwan University, Taipei City, Taiwan

Respir Med Case Rep 2022 16;37:101650. Epub 2022 Apr 16.

Department of Medicine II, Division of Pulmonology, Medical University of Vienna, Vienna, Austria.

A 53-year old female patient with history of hypocomplementaemic urticarial vasculitis syndrome (HUVS) and polyarteritis nodosa presented with progressive dyspnoea on exertion due to emphysema. Lung function revealed a severe obstructive ventilator disorder with a forced expiratory volume in 1 second of 22% of predicted, and a significant hyperinflation with a residual volume of 321% of predicted. Multi-detector computed tomography (MDCT) scan and quantitative CT analysis (StratX software) confirmed a lower lobe predominant emphysema. Read More

Cureus 2022 Mar 23;14(3):e23429. Epub 2022 Mar 23.

Department of Nephrology, University of Connecticut, Farmington, USA.

Hypocomplementemia urticarial vasculitis syndrome (HUVS) is a rare form of systemic vasculitis which is characterized by the presence of urticaria and hypocomplementemia. The presence of recurrent and chronic urticarial rash is the dominant clinical finding in HUVS. Other manifestations including angioedema, arthritis, gastrointestinal symptoms, ocular inflammation, pulmonary involvement, renal involvement, and central nervous system involvement are also seen. Read More

J Dtsch Dermatol Ges 2022 06 24;20(6):881-884. Epub 2022 Apr 24.

Unidad de Gestión Clínica de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario Puerta del Mar, Cádiz, Spain.

J Assoc Physicians India 2022 Feb;70(2):11-12

Associate Professor, Dept. of Internal Medicine, Goa Medical College, Goa.

Background And Objectives: Henoch Schonlein purpura (HSP) is a small vessel vasculitic disorder common in children and has been extensively studied. Although it is known to also occur in adults there is relative paucity of data as regards to its clinical spectrum, complications and outcome, particularly in Indian context. Hence the study was undertaken with the objective to evaluate the various skin manifestations, systemic complications of HSP in adults and also compare it with data available in children in various published clinical studies. Read More

J Allergy Clin Immunol 2022 Apr;149(4):1137-1149

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address:

Urticarial vasculitis (UV) is a rare cutaneous vasculitis of small vessels characterized by recurrent episodes of wheal-like lesions that tend to last more than 24 hours, healing with a residual ecchymotic postinflammatory hyperpigmentation. The histopathologic pattern of UV is that of leukocytoclastic vasculitis, consisting of fibrinoid necrosis of dermal vessels' walls and neutrophil-rich perivascular inflammatory infiltrates. Although its etiopahogenesis remains still undefined, UV is now regarded as an immune complex-driven disease with activation of the complement cascade, leading to exaggerated production of anaphylatoxins that are responsible for neutrophil recruitment and activation. Read More

Clin Case Rep 2022 Mar 13;10(3):e05565. Epub 2022 Mar 13.

Department of Pediatrics Hamad Medical Corporation Doha Qatar.

Toxic Epidermal Necrolysis/Steven-Johnson Syndrome (TEN/SJS) is one of the most serious dermatological adverse reactions triggered mainly by drugs and less likely by infections. COVID-19 disease is caused by Sever Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) with a wide range of clinical manifestations. Skin involvement is common in COVID-19 patients including urticaria, purpura, and vasculitis. Read More

Dermatol Ther 2022 Jun 25;35(6):e15458. Epub 2022 Mar 25.

Department of Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

Currently the most powerful tool in combating the COVID-19 pandemic is vaccination against SARS-CoV-2. A growing percentage of the world's population is being vaccinated. Various vaccines are worldwide on the market. Read More

JAAD Case Rep 2022 Mar 20;21:189-191. Epub 2022 Jan 20.

Université de Montréal.

Am J Ophthalmol Case Rep 2022 Jun 18;26:101437. Epub 2022 Feb 18.

Department of Ophthalmology, China Medical University Hospital, China Medical University, Taichung, Taiwan.

Introduction: We report a male who presented with acute visual defect and was diagnosed with urticarial vasculitis with recurrent branch retinal artery occlusion (BRAO) after systemic disease survey, fluorescein angiography (FA), and MultiColor imaging (MCI).

Case Report: A 47-year-old male with a history of urticarial vasculitis presented with visual defect OD. Fundus examination showed two foci of ischemic retinal whitening beneath the inferior arcade and above the superior arcade. Read More

Pharmaceutics 2022 Jan 27;14(2). Epub 2022 Jan 27.

Department of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.

(1) Background: Colchicine is a natural alkaloid with anti-inflammatory properties used to treat various disorders, including some skin diseases. This paper aims to incorporate all the available studies proposing colchicine as a treatment alternative in the management of cutaneous conditions. (2) Methods: In this systematic review, the available articles present in various databases (PubMed, Scopus-Embase, and Web of Science), proposing colchicine as a treatment for cutaneous pathological conditions, have been selected. Read More

BMC Nephrol 2022 02 16;23(1):67. Epub 2022 Feb 16.

Department of Nephrology, Aix-Marseille Univ, Hôpital de la Conception, AP-HM, 147 Bd Baille, 13005, Marseille, France.

Background: Hypocomplementemic urticarial vasculitis (HUV) is a rare systemic vasculitis. We aimed to describe the kidney involvement of HUV in a multicenter national cohort with an extended follow-up.

Methods: All patients with HUV (international Schwartz criteria) with a biopsy-proven kidney involvement, identified through a survey of the French Vasculitis Study Group (FVSG), were included. Read More

Int J Dermatol 2022 Feb 15. Epub 2022 Feb 15.

Dermatology Department, Hospital Universitario San Cecilio, Granada, Spain.

Z Rheumatol 2022 May 27;81(4):270-279. Epub 2022 Jan 27.

Klinik für Rheumatologie und klinische Immunologie, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

Small vessel vasculitis is characterized by a necrotizing inflammation of the vessel wall predominantly with involvement of small intraparenchymal arteries, arterioles, capillaries and venules. Medium-sized and occasionally large vessels can also be involved. Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (granulomatosis with polyangiitis, microscopic polyangiitis, eosinophilic granulomatosis with polyangiitis) are differentiated from immune complex vasculitides based on immunopathological and serological aspects. Read More

Int J Dermatol 2022 Jan 24. Epub 2022 Jan 24.

Dermatology Department of the Hospital Universitario 12 de Octubre, Madrid, Spain.

Clin Dermatol 2022 Jan 1. Epub 2022 Jan 1.

Department of Dermatology, Koç University School of Medicine, Istanbul, Turkey. Electronic address:

Annular urticarial configurations are often associated with acute and chronic urticaria. Such lesions may be short-lived, migratory, transient, pruritic, and resolving with no residual evidence, making the diagnosis of urticaria an obvious one. Annular urticarial lesions can be the presenting signs of various cutaneous and systemic diseases. Read More

Rheumatol Adv Pract 2021 24;5(3):rkab090. Epub 2021 Nov 24.

Rheumatology Department, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, UK.

Dermatol Ther 2022 Mar 29;35(3):e15282. Epub 2021 Dec 29.

Dermatology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Acta Dermatovenerol Alp Pannonica Adriat 2021 Dec;30(4):161-164

Hematological Laboratory, Second Department of Internal Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece.

Chronic lymphocytic leukemia (CLL) is a type of malignant lymphoproliferative disorder characterized by a rapid and uncontrolled increase in lymphoid cells, mostly monoclonal B-cells (B-CLL). Patients with CLL may present cutaneous lesions that can be classified as either "specific" or "non-specific." In CLL patients, specific skin eruptions arise from leukemic cell infiltration, recognized histopathologically in tissue sample biopsy. Read More

Clin Dermatol 2021 Nov-Dec;39(6):966-984. Epub 2021 Jul 25.

Discovery Life Sciences, Powell, Ohio; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.

A total of 22 patients who had developed an adverse cutaneous reaction to the Moderna or Pfizer vaccine underwent biopsies. Each patient was assessed light microscopically, and, in select biopsies, spike glycoprotein and cytokine assessment were also conducted. The patients developed self-limited cutaneous reactions often described clinically as urticarial or eczematous within 1 day to 4 weeks after receiving the first or second dose of the Pfizer or Moderna vaccine. Read More

Clin Mol Allergy 2021 Dec 5;19(1):22. Epub 2021 Dec 5.

SOD Immunoallergologia, AOU Careggi, Florence, Italy.

Background: Asthma, and severe asthma in particular, is often managed within a specialized field with allergists and clinical immunologists playing a leading role. In this respect, the National Scientific Society SIAAIC (Società Italiana di Allergologia, Asma ed Immunologia Clinica), structured in Regional and Inter-Regional sections, interviewed a large number of specialists involved in the management of this respiratory disease.

Methods: A survey entitled "Management of patients with asthma and severe asthma" based on 17 questions was conducted through the SIAAIC newsletter in 2019 thanks to the collaboration between GlaxoSmithKline S. Read More

Int J Dermatol 2021 Dec 5. Epub 2021 Dec 5.

Texas A&M College of Medicine, Dallas, TX, USA.