21,726 results match your criteria Urticaria Solar


The Prevalence of Atopic Dermatitis and Chronic Spontaneous Urticaria are Associated with Parental Socioeconomic Status in Adolescents in China.

Acta Derm Venereol 2018 Dec 6. Epub 2018 Dec 6.

Department of Dermatology, Xiangya Hospital, 410008 Changsha, China.

The association of atopic dermatitis and chronic spontaneous urticaria with socioeconomic status has been little studied. The aim of this study was to investigate the prevalence of skin diseases and their association with socioeconomic status in adolescents in China. A cross-sectional study was conducted at a comprehensive university. Read More

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December 2018
3 Reads

Unexpected photosensitivity - a patient with dermatomyositis and concomitant solar urticaria.

J Eur Acad Dermatol Venereol 2018 Dec 5. Epub 2018 Dec 5.

Dept. of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany.

Dermatomyositis (DM) is a connective tissue disease with rare incidence, characterized by progressive muscle weakness and typical cutaneous manifestations. Its pathogenesis is still incompletely understood, but next to genetic predisposition environmental factors seem to be implicated in the development of DM (1). Photosensitivity is one important factor for the onset and exacerbation of DM, which is corroborated by the distribution of the cutaneous features on sun-exposed areas and disease photoaggravation (2,3). Read More

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December 2018

Solar Angioedema: A report of a patient and a review of literature.

Photodermatol Photoimmunol Photomed 2018 Dec 5. Epub 2018 Dec 5.

Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.

Solar angioedema is a rare photodermatosis, with only 11 reported patients worldwide. Patients develop facial (predominately eyelids, lips) and/or acral swelling hours after sun exposure, especially while on vacation to tropical areas. Management includes photoprotection and sun avoidance; preemptive antihistamines have been tried with minimal effect. Read More

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December 2018
1 Read

Water-related dermatoses.

Int J Dermatol 2018 Dec 2. Epub 2018 Dec 2.

Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon.

Water-related dermatoses are a spectrum of diseases that are associated with water exposure. They result either from the direct influence of water or after injury from water inhabitants. In this review, clinical entities that manifest after water exposure (aquagenic pruritus, aquagenic urticaria, and aquagenic wrinkling of the palms) will be discussed with particular focus on the reported pathogenesis. Read More

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December 2018

[Classification and pathophysiology of angioedema].

Hautarzt 2018 Nov 30. Epub 2018 Nov 30.

Klinik für Dermatologie, Venerologie und Allergologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.

Background: The classification of angioedema in daily clinical practice is often challenging.

Objectives: The goal is to review the most recent classification of angioedema and to discuss the underlying pathology.

Materials And Methods: Current guidelines and research on the pathophysiology and classification of angioedema were evaluated. Read More

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November 2018

Self-reported hypersensitivity and allergy to foods amongst Mexican adolescents: Prevalence and associated factors.

Allergol Immunopathol (Madr) 2018 Nov 29. Epub 2018 Nov 29.

Universidad Autónoma del Estado de México, Centro de Investigación en Ciencias Médicas, Estado de México, Jesús Carranza No. 205, Colonia Universidad, Toluca de Lerdo, Estado de México, C.P. 50130, Mexico.

Background: The prevalence of food allergy is on the rise on a global scale.

Objective: To determine the prevalence of food hypersensitivity (FHS) and probable food allergy (PFA), as well as the foods and factors associated with these occurrences.

Methods: A cross-sectional study was carried out among 1992 adolescents (aged 15-18 years). Read More

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November 2018

Drug-Induced Fixed Urticaria as a Presentation of NSAID Intolerance.

J Allergy Clin Immunol Pract 2018 Nov 29. Epub 2018 Nov 29.

Department of Allergy, Hospital Universitario de La Princesa, Instituto de Investigación Sanitaria Princesa (IP), Madrid, Spain; RETIC ARADYAL RD16/0006/0015, Instituto de Salud Carlos III, Madrid, Spain.

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November 2018

Afamelanotide in the Treatment of Dermatologic Disease

Skin Therapy Lett 2018 11;23(6):6-10

Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA

Afamelanotide, an α-melanocyte stimulating hormone analogue, has become an emerging therapeutic option for a variety of skin conditions previously refractory to other treatments. Its efficacy has been demonstrated in several dermatologic conditions, including erythropoietic protoporphyria (EPP), solar urticaria, polymorphic light eruption (PMLE), vitiligo, acne, and Hailey-Hailey disease. Its relatively low risk side effect profile makes it an attractive treatment option and also paves the way for innovative use in other disorders. Read More

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November 2018
2 Reads

Thyroid Autoimmunity and Autoimmunity in Chronic Spontaneous Urticaria Linked to Disease Severity, Therapeutic Response, and Time to Remission in Patients with Chronic Spontaneous Urticaria.

Biomed Res Int 2018 1;2018:9856843. Epub 2018 Nov 1.

Division of Dermatology, Department of Internal Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Background: Chronic spontaneous urticaria (CSU) is autoimmune in nature and associated with thyroid autoimmunity (TA), but evidence on autoimmunity in relation to CSU progression and prognosis is limited. We evaluated whether TA and autoimmunity in CSU are correlated with disease severity, therapeutic response, and time to remission and establish an association between CSU characteristics linked to thyroid autoantibody.

Methods: Medical records of patients diagnosed with urticaria attending outpatient dermatology clinic at a university-based hospital from 2013 to 2017 were retrospectively reviewed. Read More

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November 2018
2 Reads

Is Adenoidectomy and/or Tonsillectomy a Risk Factor for Allergic Diseases and Asthma in Adulthood?

Eurasian J Med 2018 Oct;50(3):152-155

Division of Allergy and Immunology, Department of Chest Diseases, Ankara University School of Medicine, Ankara, Turkey.

Objective: To determine the relationship between adenoidectomy and/or tonsillectomy in childhood and allergic diseases in adulthood.

Materials And Methods: A survey investigating the history of adenoidectomy and/or tonsillectomy was administered to patients that were followed-up by our department between January and June 2014 with the diagnosis of asthma, allergic rhinitis, urticaria-angioedema, drug allergy, food allergy, and venom allergy; patients willing to participate were included in the study. The relationship and risk ratios were analyzed. Read More

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October 2018

Probable contact urticaria caused by tacrolimus-containing ointment in the treatment of atopic dermatitis.

J Allergy Clin Immunol Pract 2018 Dec 1. Epub 2018 Dec 1.

Department of Dermatology and Venereology, Trakia University Stara Zagora, Bulgaria. Electronic address:

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December 2018
2 Reads

Recurrent oedema of the uvula in a patient with chronic spontaneous urticaria successfully treated with omalizumab.

Authors:
A Pannofino

J Dermatolog Treat 2018 Dec 4:1-4. Epub 2018 Dec 4.

a Allergology and Immunology Clinic , Operative Unit of Medicine , Policoro Hospital, Matera , Italy .

Uvula oedema is a condition characterized by a sensation of a foreign body in the oropharynx and difficulty to speak; sometimes, if associated to glottis oedema, difficulty to breathe and dysphonia are also present. Urticaria is a disease characterized by itching wheals on the skin, and sometimes angioedema. Chronic urticaria is spontaneous when the aetiology is unknown. Read More

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December 2018
2 Reads

Rapid, persistent, and simultaneous remission of urticaria and severe atopic dermatitis after treatment with omalizumab.

J Dermatolog Treat 2018 Dec 4:1-4. Epub 2018 Dec 4.

a Department of Dermatology , University of Rome "Tor Vergata".

This article reports the rapid and complete remission of concomitant chronic spontaneous urticaria and atopic dermatitis, obtained in a woman of 32 years, after treatment with omalizumab, without adverse events. Read More

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December 2018
2 Reads

Adverse Events in the Efficacy of Crotalidae Polyvalent Immune Fab Antivenom vs Placebo in Recovery from Copperhead Snakebite Trial.

South Med J 2018 Dec;111(12):716-720

From the Division of Emergency Medicine, Washington University School of Medicine, St Louis, Missouri, the Division of Emergency Medicine, Duke University, Durham, North Carolina, the Department of Emergency Medicine, East Carolina University Brody School of Medicine, Greenville, North Carolina, the Department of Emergency Medicine, Virginia Commonwealth University, Richmond, the Department of Emergency Medicine, Baylor College of Medicine, Houston, Texas, the Department of Emergency Medicine, University of North Carolina, Chapel Hill, North Carolina, Texas A&M Health Sciences Center, Bryan, Rocky Mountain Poison & Drug Center, Denver, Colorado, the Department of Emergency Medicine, UT Southwestern Medical Center, Dallas, Texas, the Department of Emergency Medicine, Augusta University, Augusta, Georgia, the Department of Emergency Medicine, University of Virginia, Charlottesville, the Department of Surgery, East Carolina University Brody School of Medicine, Greenville, North Carolina, and the Department of Surgery, Marshall University, Huntington, West Virginia.

Objective: To compare the incidence of hypersensitivity reactions following copperhead envenomation treated with Fab antivenom (FabAV) or placebo.

Methods: Patients with copperhead snakebites received treatment and follow-up in a prospective, randomized, double-blind, placebo-controlled trial of FabAV or placebo. The treatment allocation ratio was 2:1 (FabAV:placebo). Read More

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December 2018
1 Read

Dupilumab as a novel therapy for difficult to treat chronic spontaneous urticaria.

J Allergy Clin Immunol Pract 2018 Nov 26. Epub 2018 Nov 26.

CEO and president of Urticaria Canada; Evidence Based Medical Educator Inc., 123 Edward St., Suite 920, Toronto, ON, Canada. Electronic address:

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November 2018
1 Read

Characteristics of persistent diaper dermatitis in children with food allergy.

Pediatr Dermatol 2018 Nov 28. Epub 2018 Nov 28.

Department of Pediatrics, Medical Faculty, Inonu University, Malatya, Turkey.

Background/objectives: Diaper dermatitis is often caused by irritant contact occurring beneath the diaper of an infant, and it is aggravated by factors such as dampness, friction, urea, and feces. Food-allergic patients are known to exhibit various skin lesions ranging from urticaria to eczema. This study aims to determine the relationship between persistent diaper dermatitis and food allergy. Read More

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November 2018
2 Reads

Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption.

An Bras Dermatol 2018 Nov/Dec;93(6):874-877

Department of Pathology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. Read More

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July 2017
1 Read

Anaesthetic implications of a patient with cold-induced anaphylaxis presenting to the labour ward.

Int J Obstet Anesth 2018 Sep 26. Epub 2018 Sep 26.

Chelsea and Westminster Hospital, Magill Department of Anaesthesia, London, United Kingdom.

Cold contact urticaria is a well described condition, with reactions ranging from localised wheals to systemic and anaphylactic reactions. Case reports involving anaesthetic care are rare. This report describes a patient with cold-induced urticaria with systemic reactions who had been advised to carry an adrenaline autoinjector. Read More

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September 2018
1 Read

Adaptation and Validation of the Korean Version of the Urticaria Control Test and Its Correlation With Salivary Cortisone.

Allergy Asthma Immunol Res 2019 Jan;11(1):55-67

Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.

Purpose: Frequent changes in chronic urticaria (CU) activity over time can cause psychological stress, which also serves as a trigger of CU. To measure the control status of CU, the Urticaria Control Test (UCT) was developed in Germany. This study aimed to investigate the validity, reliability and responsiveness to changes in CU for the Korean version of the UCT (K-UCT) and its relation with salivary cortisol and cortisone levels. Read More

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January 2019
4 Reads

Causal Relationship Between Anti-TPO IgE and Chronic Urticaria by and Tests.

Allergy Asthma Immunol Res 2019 Jan;11(1):29-42

Group of Experimental and Clinical Allergy, IPS Universitaria, University of Antioquia, Medellín, Colombia.

Purpose: Immunoglobulin (Ig) E autoantibodies against thyroid antigens such as thyroid peroxidase (TPO) have been demonstrated in chronic spontaneous urticaria (CSU) patients in higher frequency than healthy subjects. However, if these IgE autoantibodies can trigger urticaria is still a matter of study. The aim of this study was to investigate the relationship between concomitant IgE autoantibodies against thyroid antigens in CSU. Read More

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January 2019
1 Read

Anti-TPO IgE Autoantibody in Chronic Urticaria: Is It Clinically Relevant?

Allergy Asthma Immunol Res 2019 Jan;11(1):1-3

Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.

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January 2019
1 Read

How to discontinue omalizumab in chronic spontaneous urticaria?

Allergy 2018 Nov 26. Epub 2018 Nov 26.

Division of Allergy and Clinical Immunology, Department of Chest Diseases, Erciyes University School of Medicine, Kayseri, Turkey.

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November 2018
1 Read

Use of Dapsone in the Treatment of Chronic Idiopathic and Autoimmune Urticaria.

JAMA Dermatol 2018 Nov 21. Epub 2018 Nov 21.

The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.

Importance: The first-line treatment for patients with chronic spontaneous urticaria (CSU), which is divided into idiopathic and autoimmune subtypes, consists of H1-antihistamines. However, limited evidence guides the treatment of CSU after maximal therapy with antihistamines fails. Two randomized clinical trials suggest that dapsone may be a successful second-line therapy. Read More

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November 2018
1 Read

α-Gal Syndrome vs Chronic Urticaria.

JAMA Dermatol 2018 Nov 21. Epub 2018 Nov 21.

Department of Medicine, University of Virginia, Charottesville.

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November 2018
3 Reads

Occupational rhinitis, asthma, and contact urticaria from IgE-mediated allergy to pork.

Am J Ind Med 2018 Nov 25. Epub 2018 Nov 25.

Finnish Institute of Occupational Health (FIOH), Helsinki, Finland.

We describe four cases of slaughterhouse workers with occupational immediate allergy to raw pork allergens, confirmed by positive skin prick testing and specific immunoglobulin E (IgE) antibodies. Our first patient was diagnosed with occupational asthma from raw pork allergens. Two patients were diagnosed with occupational rhinitis caused by raw pork allergens, which was confirmed by a nasal provocation test. Read More

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November 2018
1 Read

Focus on the role of substance P in chronic urticaria.

Clin Mol Allergy 2018 19;16:24. Epub 2018 Nov 19.

4Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari-Aldo Moro, Bari, Italy.

Background: Emerging data have strengthened the importance of substance P (SP) as a proinflammatory mediator in human pathology. A role for SP in the pathogenesis of urticaria has long been hypothesized.

Methods: Literature data regarding the possible role of SP in chronic urticaria/chronic spontaneous urticaria (CSU) have been reviewed and summarized in this manuscript. Read More

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November 2018
1 Read

Report: A comparative study of loratidine physiochemical properties from different brands.

Pak J Pharm Sci 2018 Nov;31(6):2569-2574

Faculty of Pharmacy, Jinn ah University for Women, Karachi, Pakistan.

Loratidine is a piperidine derivative resemble to azatadine long acting non sedating commonly used for the treatment of allergic condition like watery or itchy eyes, runny nose, chronic urticaria or throat itching. In the present study different brands of loratidine were evaluated for the weight variation, hardness, friability, disintegration time and dissolution. Dissolution release study performed by using paddle method (USP 2) in 900 ml of 0. Read More

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November 2018
1 Read

Model-informed pediatric development applied to bilastine: Analysis of the clinical PK data and confirmation of the dose selected for the target population.

Eur J Pharm Sci 2018 Nov 20. Epub 2018 Nov 20.

Drug Modeling & Consulting, Dynakin, SL, Bilbao, Spain.

Bilastine is a non-sedating second-generation H antihistamine approved for treatment of allergic rhinoconjunctivitis (AR) and urticaria (U) in adults at the oral (p.o.) dose of 20 mg once daily (OD). Read More

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November 2018
3 Reads

Basophil activation test in children with autoimmune chronic spontaneous urticaria: Is it ready for clinical practice?

Immunobiology 2018 Nov 13. Epub 2018 Nov 13.

Department of Pediatrics, Foundation IRCCS Policlinico San Matteo, Pavia, Italy.

Introduction: Chronic spontaneous urticaria (CSU) is characterized by recurrent itchy wheals, angioedema or both, that persist for longer than six weeks. In children, up to 40% of chronic spontaneous urticaria is due to mast cells and basophils-activating autoantibodies, mostly directed against the IgE high-affinity receptor subunit (FcεRI). Indirect basophil activation test (BAT) has been proposed in the diagnosis of autoimmune urticaria. Read More

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November 2018
3 Reads

Comorbidities in Dermatology: What's Real and What's Not.

Dermatol Clin 2019 Jan 1;37(1):65-71. Epub 2018 Nov 1.

Department of Dermatology, George Washington Medical Faculty Associates, 2150 Pennsylvania Avenue Northwest, Suite 2B-427, Washington, DC 20037, USA; Department of Dermatology, George Washington School of Medicine and Health Sciences, 2150 Pennsylvania Avenue Northwest, Suite 2B-427, Washington, DC 20037, USA. Electronic address:

Comorbidities affecting dermatologic patients are of significant importance to providers and highly relevant for appropriate patient counseling, screening practices, prevention, and treatment. This article seeks to highlight several of the newest findings in the literature regarding comorbidities associated with dermatologic diseases including atopic dermatitis, hidradenitis suppurativa, alopecia areata, chronic urticaria, and the pemphigus family of immunobullous diseases. Further investigation is needed for associations between atopic dermatitis and pancreatic cancer and pemphigus family diseases and chronic obstructive pulmonary disease in order to better characterize the strength of these associations and clinical relevance. Read More

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January 2019
3 Reads

Differences in chronic spontaneous urticaria between Europe and Central/South America: results of the multi-center real world AWARE study.

World Allergy Organ J 2018 16;11(1):32. Epub 2018 Nov 16.

17Novartis Pharma AG, Basel, Switzerland.

Background: Global chronic urticaria (CU) disease experience and management is not well documented. This study descriptively compares these aspects among CU patients residing in Europe (EU) and Central and South America (C/SA).

Methods: AWARE (A World-wide Antihistamine-Refractory chronic urticaria patient Evaluation) is a global prospective, non-interventional study of CU in the real-world setting. Read More

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November 2018
1 Read

Two decades with omalizumab: what we still have to learn.

Biologics 2018 26;12:135-142. Epub 2018 Oct 26.

Department of Medicine and Surgery, University of Parma, Parma, Italy.

From its availability for clinical use nearly two decades ago for severe asthma, omalizumab has gained strong evidence of efficacy and safety in the treatment of severe asthma not controlled by standard-of-care therapy. It has been acknowledged by Global Initiative on Asthma guidelines as add-on therapy against severe uncontrolled asthma. Thanks to controlled trials supporting its efficacy, omalizumab has also been licensed for the treatment of chronic spontaneous urticaria. Read More

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October 2018
2 Reads

[ALLERGIC SKIN DISORDERS].

Authors:
Norito Katoh

Arerugi 2018 ;67(9):1243-1247

Dermatology, Kyoto Prefectural University of Medicine Graduate School of Medical Science.

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January 2018
2 Reads

Hereditary angioedema with C1 inhibitor (C1-INH) deficit: the strength of recognition (51 cases).

Braz J Med Biol Res 2018 Nov 14;51(12):e7813. Epub 2018 Nov 14.

Disciplina de Imunologia Clínica, Faculdade de Medicina do ABC, Santo André, SP, Brasil.

Hereditary angioedema (HAE) is a rare autosomal dominant disease due to C1 esterase inhibitor deficiency (C1-INH). The disease is characterized by subcutaneous and submucosal edema in the absence of urticaria due to the accumulation of bradykinin. This descriptive study aimed to evaluate the clinical characteristics of patients with a confirmed diagnosis of HAE referred to our Outpatient Clinic between December 2009 and November 2017. Read More

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November 2018
2 Reads

Chronic spontaneous urticaria treated with omalizumab: report of two cases.

J Dermatolog Treat 2018 Nov 21:1-9. Epub 2018 Nov 21.

a Department of Dermatology , Papardo Hospital , Messina , Italy.

Chronic spontaneous urticaria (CSU) is a relatively common skin disease whose etiopathogenesis, as well as other factors influencing disease manifestations, are not fully understood. Mast cell function is recognised as having a central role in CSU signs and symptoms. Therapeutic options are limited; a number of drugs, recommended by international guidelines for the management of urticaria, lack regulatory approval for CSU and are prescribed off label. Read More

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November 2018
5 Reads

Omalizumab treatment in a 12 year-old girl with chronic spontaneous urticaria.

J Dermatolog Treat 2018 Nov 21:1-6. Epub 2018 Nov 21.

a Department of Clinical and Experimental Medicine , University of Catania , Catania , Italy.

Omalizumab is a recombinant humanized IgG monoclonal antibody, which binds the Fc region of free IgE prevent its binding to its high-affinity receptor (FcεR1) on mast cells and basophils. Omalizumab was approved as add-on therapy for moderate-to-severe persistent allergic asthma and for patients with chronic spontaneous urticaria resistant to antihistamine treatment. This article reports effective and safe treatment of a 12 years old girl with add-on omalizumab. Read More

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November 2018
1 Read

The overlap syndrome of urticaria and gastroesophageal reflux disease.

PLoS One 2018 20;13(11):e0207602. Epub 2018 Nov 20.

Aggregate Post Graduate School in Allergology and Clinical Immunology of Campania University L. Vanvitelli, Naples, Italy and of Federico II University, Naples, Italy.

Background: One-quarter of systemic symptoms associated with chronic spontaneous urticaria (CSU) are related to gastrointestinal complaints (GICs).

Objectives: To investigate the prevalence and features of urticaria-overlapping GICs.

Methods: In this retrospective cross-sectional survey, 1426 consecutive outpatients were observed at our University Department. Read More

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November 2018
3 Reads

Oral suplatast tosilate for the treatment of urticaria pigmentosa, skin lesion in mastocytosis.

Int J Dermatol 2018 Nov 19. Epub 2018 Nov 19.

Department of Dermatology, Sakai City Medical Center, Osaka, Japan.

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November 2018
3 Reads

Wong-type dermatomyositis during anti-PD-1 therapy.

JAAD Case Rep 2018 Nov 10;4(10):1049-1051. Epub 2018 Nov 10.

Department of Dermatology, University of California, San Francisco, San Francisco, California.

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November 2018
3 Reads

Predictors of response to omalizumab and relapse in chronic spontaneous urticaria: a study of 470 patients.

J Eur Acad Dermatol Venereol 2018 Nov 19. Epub 2018 Nov 19.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano, Milan, Italy.

Background: Chronic spontaneous urticaria (CSU) is defined as spontaneous occurrence of wheals and/or angioedema for ≥6 weeks. Omalizumab is a monoclonal anti-IgE antibody effective in refractory CSU, but its mechanism of action and markers predictive of response remain not completely defined.

Objectives: To correlate baseline levels of two proposed biomarkers, total IgE (bIgE) and d-dimer (bd-dimer), and clinical parameters to omalizumab response and to relapses after drug withdrawal. Read More

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November 2018
6 Reads

Rash induced by enteral vancomycin therapy in an older patient in a long-term care ventilator unit: case report and review of the literature.

Allergy Asthma Clin Immunol 2018 6;14:73. Epub 2018 Nov 6.

Chronic Ventilator Unit, Herzog Medical Center, Givat Shaul St, POB 3900, 91035 Jerusalem, Israel.

Background: Oral vancomycin is a first-line treatment for severe colitis. Oral vancomycin is perceived to lack systemic absorption or systemic adverse effects; however, a few cases of hypersensitivity to oral vancomycin have been reported, all in hospitalized patients.

Case Presentation: In the present case, a 66-year-old woman with end-stage neurodegenerative disease residing in a long-term care facility developed a maculopapular rash following treatment with enteral vancomycin for recurrent colitis. Read More

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November 2018
4 Reads

Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort.

Authors:
Eden Lake

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Loyola Univ Medical Center Dermatology, 321 N La Grange Rd, La Grange Park, IL. Electronic address:

Acquired cold urticaria (ACU) is characterized by the development of wheals, angioedema, or both after cold exposure. Age at diagnosis, disease severity, and response to the ice cube challenge test predicted both prognosis and response to therapy. Proper characterization of the type of acquired cold urticaria allows for appropriate counseling and choice of therapy. Read More

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November 2018
6 Reads

Use of antipsychotic drugs in dermatology.

Clin Dermatol 2018 Nov - Dec;36(6):765-773. Epub 2018 Aug 16.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Antipsychotic drugs can be beneficial in dermatology because of their both central nervous system and peripheral effects. All antipsychotic drugs have a central postsynaptic dopamine D2 receptor blocking effect, which underlies their antipsychotic action. The antipsychotic drugs have varying degrees of histamine H1-receptor, cholinergic muscarinic receptor, and α1-adrenergic receptor blocking effects, which can affect cutaneous perception and the autonomic reactivity of the skin and can be potentially beneficial in the management of certain histamine or sympathetically mediated dermatologic manifestations (eg, urticaria, pruritus, hyperhidrosis). Read More

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August 2018
9 Reads

Use of antiepileptic mood stabilizers in dermatology.

Clin Dermatol 2018 Nov - Dec;36(6):756-764. Epub 2018 Aug 16.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Several antiepileptic drugs (AEDs) are approved by the US Food and Drug Administration for the treatment of bipolar disorder (valproic acid, divalproex, lamotrigine, carbamazepine) and some cutaneous neuropathic pain syndromes (carbamazepine, gabapentin, pregabalin). The AEDs may be effective in the management of (1) chronic pruritus, including pruritus due systemic disease, including uremia, neuropathic pain, neuropathic pruritus, and complex cutaneous sensory syndromes, especially where central nervous system (CNS) sensitization plays a role; (2) management of emotional dysregulation and the resultant repetitive self-excoriation or other cutaneous self-injury in patients who repetitively stimulate or manipulate their integument to regulate emotions (prurigo nodularis, lichen simplex chronicus, skin picking disorder, trichotillomania); (3) management of dermatologic clinical manifestations associated with autonomic nervous system activation (hyperhidrosis, urticaria, flushing; these often occur in conjunction with psychiatric disorders with prominent autonomic activation and dysregulation, eg, social anxiety disorder, posttraumatic stress disorder); and (4) when certain anticonvulsants have a direct therapeutic effect (eg, in psoriasis); currently the use of AEDs for such cases is largely experimental. Gabapentin (dosage range 300-3600 mg daily) is the most widely studied AED mood stabilizer in dermatology and is especially effective in situations where CNS sensitization is a mediating factor. Read More

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August 2018
5 Reads

Psychodermatology: An Indian perspective.

Clin Dermatol 2018 Nov - Dec;36(6):737-742. Epub 2018 Aug 16.

Department of Dermatology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address:

Psychodermatology, a relatively neglected branch of dermatology in India, refers to a holistic approach to skin diseases involving not only the mind and skin, but also the cutaneous effects of psychologic stress. Among many Indian people, culture, religion, the belief in karma, and the tendency to prefer indigenous medical systems can all have a major impact on lifestyle, as well as the approach to managing various diseases, including dermatologic conditions. The origin of psychodermatology in India can be traced to Buddha's period. Read More

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August 2018
3 Reads

A review of non-glove personal protective equipment-related occupational dermatoses reported to EPIDERM between 1993 and 2013.

Contact Dermatitis 2018 Nov 14. Epub 2018 Nov 14.

Centre for Occupational and Environmental Health, University of Manchester, United Kingdom.

Background: Personal protective equipment (PPE) is defined as equipment that protects the wearer's body against health/safety risks at work. Gloves are a cause of many dermatoses. Non-glove PPE constitutes a wide array of garments. Read More

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November 2018
4 Reads

Acute urticaria: an extremely rare adverse effect of levonorgestrel-releasing intrauterine system as a possible manifestation of progestogen hypersensitivity syndrome.

Postepy Dermatol Alergol 2018 Oct 19;35(5):530-531. Epub 2018 Jul 19.

Chair of Internal Medicine and Department of Internal Medicine in Nursing, Medical University of Lublin, Lublin, Poland.

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October 2018

The effect of omalizumab treatment on IgE and other immunoglobulin levels in patients with chronic spontaneous urticaria and its association with treatment response.

Postepy Dermatol Alergol 2018 Oct 19;35(5):516-519. Epub 2018 Jul 19.

Department of Allergy and Clinical Immunology, Adnan Menderes University, Aydın, Turkey.

Introduction: Suppression of free immunoglobulin E (IgE) levels and an increase in total IgE levels are observed during omalizumab treatment. However, whether omalizumab has any effect on other immunoglobulins is unknown.

Aim: To investigate the effect of omalizumab treatment on serum IgE and other immunoglobulins, and demonstrate any association with response to treatment in patients with chronic spontaneous urticaria (CSU). Read More

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October 2018
5 Reads