558 results match your criteria Urticaria Pressure

Delayed Pressure Urticaria: Clinical and Diagnostic Features and Response to Omalizumab.

Int Arch Allergy Immunol 2022 May 24:1-6. Epub 2022 May 24.

Allergy Department, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.

Background: Delayed pressure urticaria (DPU) is a rare form of chronic inducible urticaria (CIndU) when it manifests alone. Treatment of DPU is disappointing owing to the lack of response to antihistamines, even when up-dosing. In addition, the absence of randomized clinical trials and the low number of patients included in the studies mean that there is little scientific evidence for the validity of omalizumab in DPU. Read More

View Article and Full-Text PDF

Successful Desensitization to mRNA COVID-19 Vaccine in a Case Series of Patients With a History of Anaphylaxis to the First Vaccine Dose.

Front Allergy 2022 2;3:825164. Epub 2022 Feb 2.

Division of Allergy and Clinical Immunology, Department of Medicine, McGill University Health Centre, McGill University, Montreal, QC, Canada.

Background: Coronavirus disease 2109 (COVID-19) vaccines have recently been approved to curb the global pandemic. The risk of allergic reactions to the vaccine polyethylene glycol (PEG) component has raised significant public concern. Desensitization is suggested in cases of vaccine related hypersensitivity reactions. Read More

View Article and Full-Text PDF
February 2022

The First Case of Erythritol-Induced Anaphylaxis in Korea.

J Korean Med Sci 2022 Mar 14;37(10):e83. Epub 2022 Mar 14.

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Pusan National University Hospital, Busan, Korea.

Erythritol is a natural sugar alcohol found in some fruits and fermented foods, which is used as a dietary sweetener because it has few calories. Here, we describe a 36-year-old woman who experienced anaphylaxis upon ingestion of an erythritol-containing drink. She presented to the emergency department with dyspnea and angioedema after drinking a peach-containing diet beverage. Read More

View Article and Full-Text PDF

Indigo Carmine Hemodynamic Studies to Treat Vasoplegia Induced by Compound 48/80 in a Swine Model of Anaphylaxis.

Braz J Cardiovasc Surg 2022 03 10;37(1):20-28. Epub 2022 Mar 10.

Department of Surgery and Anatomy, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, Brazil.

Introduction: There are many reasons to believe that the nitric oxide/guanosine 3'5' - cyclic monophosphate (or NO/cGMP) pathway on vasoplegic states is underestimated. To study indigo carmine (IC) as an alternative to methylene blue was the investigation rationale.

Methods: The IC (3mg/kg intravenous infusion) study protocol included five experimental groups; 1) Control group - saline was injected at 0 and 10 minutes; 2) IC group - IC was injected at 0 and saline at 10 minutes; 3) compound 48/80 (C48/80) group - C48/80 was injected at 0 minute and saline at 10 minutes; 4) C48/80 + IC group - C48/80 was injected at 0 minute and IC at 10 minutes; and 5) IC + C48/80 group - IC was injected at 0 minute and C48/80 at 10 minutes. Read More

View Article and Full-Text PDF

Effects of Low-Dose Aspirin Combined with Vitamin E on the Incidence of Intrauterine Growth Restriction and Hemorheological Indexes of Pregnant Women in Patients with Gestational Hypertension.

Comput Math Methods Med 2022 21;2022:6328807. Epub 2022 Feb 21.

First People's Hospital of Linping District, Hangzhou 311100, China.

Objective: To investigate the effect of low-dose aspirin combined with vitamin E on the incidence of intrauterine growth restriction and hemorheological indexes of pregnant women in patients with gestational hypertension.

Method: 134 elderly patients with chronic urticaria treated in our hospital from November 2017 to November 2020 were studied. According to the treatment methods, they were randomly divided into observation and control groups. Read More

View Article and Full-Text PDF

Patch-testing conundrum: Interpretation in the setting of delayed pressure urticaria.

Contact Dermatitis 2022 06 2;86(6):553-554. Epub 2022 Mar 2.

Department of Dermatology, University of Texas Health Science Center at Houston, Houston, Texas, USA.

View Article and Full-Text PDF

Stability-indicating liquid chromatography method development and validation for impurity profiling of montelukast sodium in bulk drug and tablet dosage form.

Biomed Chromatogr 2022 Apr 17;36(4):e5330. Epub 2022 Jan 17.

Department of Analytical Research, Aurex Laboratories LLC, East Windsor, NJ, USA.

Montelukast sodium (MLS) is a leukotriene receptor antagonist drug used in the treatment of asthma, bronchospasm, allergic rhinitis and urticaria. A reversed-phase high performance liquid chromatography method was developed to separate, identify and quantitative determination of MLS and its eight known organic impurities in tablet dosage form using a C column and mobile phases consisting of a gradient mixture of pH 2.5 phosphate buffer and acetonitrile. Read More

View Article and Full-Text PDF

A comprehensive strategy for quality evaluation of Wushe Zhiyang Pills by integrating UPLC-DAD fingerprint and multi-ingredients rapid quantitation with UPLC-MS/MS technology.

J Pharm Biomed Anal 2022 Feb 29;210:114556. Epub 2021 Dec 29.

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, China. Electronic address:

Wushe Zhiyang Pills (WZP), a classical traditional Chinese medicine (TCM) formula, has been extensively used for the treatment of chronic urticaria and other relevant dermatologic diseases. In this study, a holistic method combining ultra-performance liquid chromatography coupled with diode array detector (UPLC-DAD) fingerprint and multi-components quantitative analysis was developed and validated for quality evaluation of WZP. As a result, a total of 34 characteristic peaks were screened to assess the chemical similarities of 16 batches of WZP samples. Read More

View Article and Full-Text PDF
February 2022

Systemic Sclerosis in Zimbabwe: Autoantibody Biomarkers, Clinical, and Laboratory Correlates.

Front Immunol 2021 9;12:679531. Epub 2021 Nov 9.

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom.

Introduction: Systemic sclerosis (SScl) is an autoimmune disease whose prevalence is rarely reported in Africa. Autoantibodies are the biomarkers of the condition, precede overt disease and determine disease phenotypes. SSc specific autoantibodies also vary between racial groupings. Read More

View Article and Full-Text PDF
January 2022

Redback spider bites in children in South Australia: A 10-year review of antivenom effectiveness.

Emerg Med Australas 2022 Apr 23;34(2):230-236. Epub 2021 Sep 23.

Paediatric Emergency Department, Flinders Medical Centre, Adelaide, South Australia, Australia.

Objective: To describe the South Australian paediatric redback spider bite experience and to examine the hypothesis that redback antivenom (RBAV) treatment in children is clinically effective.

Methods: Retrospective chart review of all children under 18 years of age presenting to the EDs of the three major paediatric or mixed hospitals in Adelaide, South Australia, with a discharge diagnosis of redback spider envenomation between 1 January 2010 and 31 March 2020. The main outcome measures include: patient and bite demographics; presenting symptoms and signs; treatment provided; clinical effects at 2 h post RBAV administration on pain, diaphoresis, blood pressure, heart rate and systemic features; overall clinical impression of RBAV effectiveness and resolution of symptoms prior to discharge. Read More

View Article and Full-Text PDF

Anaphylactic shock in a patient with severe aortic stenosis treated with adrenaline and landiolol for circulatory management: A case report.

Medicine (Baltimore) 2021 Sep;100(35):e27135

Department of Anesthesiology and Intensive Care Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

Rationale: We present the first case of a patient with severe aortic stenosis who developed anaphylactic shock and was successfully treated with adrenaline and landiolol, a highly selective β1-receptor blocker, to prevent disruption of the myocardial oxygen supply-demand balance caused by tachycardia.

Patient Concerns: An 86-year-old woman was scheduled for simultaneous anterior-posterior fixation for a burst fracture of the 12th thoracic vertebra; 200 mg sugammadex, a neuromuscular blocking agent antagonist, was administered postoperatively, and she was extubated without complications. However, 6 min after extubation, her blood pressure decreased abruptly to 55/29 mm Hg, and her heart rate increased to 78 bpm. Read More

View Article and Full-Text PDF
September 2021

Association of Variants Near the Bradykinin Receptor B Gene With Angioedema in Patients Taking ACE Inhibitors.

J Am Coll Cardiol 2021 08;78(7):696-709

Laboratory for Molecular Cardiology, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; Laboratory for Molecular Cardiology, Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.

Background: Angioedema is a rare but potentially life-threatening adverse reaction associated with angiotensin-converting enzyme (ACE) inhibitors. Identification of potential genetic factors related to this adverse event may help identify at-risk patients.

Objectives: The aim of this study was to identify genetic factors associated with ACE inhibitor-associated angioedema. Read More

View Article and Full-Text PDF

A novel murine in vivo model for acute hereditary angioedema attacks.

Sci Rep 2021 08 5;11(1):15924. Epub 2021 Aug 5.

Office of Biotechnology Products, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, US Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA.

Hereditary Angioedema (HAE) is a rare genetic disease generally caused by deficiency or mutations in the C1-inhibitor gene, SERPING1, a member of the Serpin family. HAE results in acute attacks of edema, vasodilation, GI pain and hypotension. C1INH is a key inhibitor of enzymes controlling complement activation, fibrinolysis and the contact system. Read More

View Article and Full-Text PDF

Echis coloratus envenomation in children: a retrospective case series.

Clin Toxicol (Phila) 2022 Mar 28;60(3):293-297. Epub 2021 Jul 28.

Pediatric Intensive Care Unit, Soroka Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheba, Israel.

Background: Antivenom has been used successfully to treat systemic and progressive, local manifestations of envenomations inflicted by , the second most common cause of snake envenomation in Israel. There is a paucity of published data regarding the use of monovalent (equine) immunoglobulin G antivenom in children. This study describes outcomes from the regimen used in two large, tertiary care pediatric centers. Read More

View Article and Full-Text PDF

Methimazole Desensitization in a 4-Year-Old With Refractory Graves Disease.

AACE Clin Case Rep 2021 Jul-Aug;7(4):273-276. Epub 2021 Feb 20.

Department of Pediatrics, Division of Diabetes and Endocrinology.

Objective: To describe a 4-year-old girl with Graves disease and methimazole allergy who underwent desensitization, allowing continued methimazole use when other treatments were contraindicated.

Methods: We formulated a desensitization plan utilizing cetirizine and prednisone for a patient with previously diagnosed Graves disease who developed urticaria and arthralgias from methimazole. She was admitted for monitoring of rash, urticaria, angioedema, and anaphylaxis. Read More

View Article and Full-Text PDF
February 2021

Bullous delayed-pressure urticaria masquerading as safety footwear contact dermatitis.

Contact Dermatitis 2021 Dec 2;85(6):708-710. Epub 2021 Aug 2.

Dermatology Department, University Hospital of Guadalajara, Guadalajara, Spain.

View Article and Full-Text PDF
December 2021

Omalizumab in chronic inducible urticaria: A retrospective, real-life study.

Ann Dermatol Venereol 2021 12 8;148(4):262-265. Epub 2021 Jul 8.

Service de dermatologie, CHU de Lille, 59000 Lille, France; Inserm, U1286 - INFINITE - Institute for Translational Research in Inflammation, CHU de Lille, University Lille, 59000 Lille, France.

View Article and Full-Text PDF
December 2021

The evaluation of patients with optic disc edema: A retrospective study.

North Clin Istanb 2021 14;8(3):280-285. Epub 2021 Apr 14.

Department of Ophthalmology, Kahramanmaras Sutcu Imam University Faculty of Medicine, Kahramanmaras, Turkey.

Objective: Optic disc edema is among major problems that neuro-ophthalmology clinics encounter. We intended to analyze patients with optic disc edema in this article.

Methods: Data related to the main complaint, associated systemic disease, visual acuity, characteristics of optic disc swelling, other ocular findings, topical or systemic drugs, treatment methods, follow-up examination, and related data of the patients were obtained retrospectively. Read More

View Article and Full-Text PDF

Spontaneous abdominal effusion in dogs with presumed anaphylaxis.

J Vet Emerg Crit Care (San Antonio) 2021 Jul 29;31(4):483-489. Epub 2021 Apr 29.

College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.

Objective: To describe patient characteristics of dogs developing spontaneous abdominal effusion in association with anaphylaxis.

Design: Retrospective study between 2010 and 2018.

Setting: University teaching hospital and referral specialty private practice emergency departments. Read More

View Article and Full-Text PDF

Systemic mastocytosis with flushing and hypotension: A case report and literature review.

Exp Ther Med 2021 Apr 25;21(4):404. Epub 2021 Feb 25.

Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China.

Systemic mastocytosis (SM) is a heterogeneous disease of the bone marrow, which is characterized by the abnormal proliferation and infiltration of mast cells in one or more organs, such as the skin, bone marrow, digestive tract, liver and spleen. Urticaria pigmentosa is a typical but infrequent manifestation of SM. Other clinical presentations are non-specific, varying from pruritus and hypotension to multiple organ dysfunction, which may be lethal when hemodynamic changes occur, such as the sharp decline in blood pressure observed in the present case. Read More

View Article and Full-Text PDF


Georgian Med News 2020 Dec(309):12-17

3"Center of Innovative Medical Technologies of the National Academy of Sciences of Ukraine".

The aim of the study is to evaluate the tolerability and effectiveness of photodynamic therapy (PDT) of patients with premalignant diseases of the vulva. The study was performed on 10 patients on the basis of the National Cancer Institute of Ukraine (Kyiv). The age of patients ranged from 31 to 67 years old (mean age: 53. Read More

View Article and Full-Text PDF
December 2020

Adverse reactions to radiopharmaceuticals: liver radiopharmaceuticals.

Nucl Med Commun 2021 04;42(4):352-359

Department of Radiopharmacy, Hacettepe University Faculty of Pharmacy, Ankara, Turkey.

Radiopharmaceuticals are radioactive compounds used in nuclear medicine, consisting of a radioactive moiety and a pharmaceutical part. Radiopharmaceuticals are used for diagnosis (predominantly) and therapy (to a lesser extent). Adverse drug reactions are undesirable, unexpected, often harmful drug responses that occur when the drug is administered in therapeutic doses. Read More

View Article and Full-Text PDF

COVID-19 pandemic and the skin: what should dermatologists know?

Clin Dermatol 2020 Nov - Dec;38(6):785-787. Epub 2020 Mar 24.

Department of Dermatology and Venereology, Acibadem City Clinic, Tokuda Hospital, Sofia, Bulgaria.

The world has changed dramatically since the COVID-19 pandemic began. In addition to our social, occupational, and personal lives, the new coronavirus also poses novel challenges for all physicians, including dermatologists. Several skin conditions have emerged, mainly as a result of prolonged contact with personal protective equipment and excessive personal hygiene. Read More

View Article and Full-Text PDF
December 2020

Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety.

PLoS One 2020 3;15(12):e0243371. Epub 2020 Dec 3.

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, United States of America.

Background: Lisinopril and losartan manufacturer labels recommend twice-daily dosing (BID) if once-daily (QDay) is insufficient to lower blood pressure (BP).

Methods And Results: Retrospective cohort study of patients taking QDay lisinopril and losartan who experienced a dose-doubling (index date). A text-processing tool categorized BID and QDay groups at the index date based on administration instructions. Read More

View Article and Full-Text PDF
January 2021

Successful treatment of delayed pressure urticaria with 300 mg of omalizumab every 14 days.

J Cosmet Dermatol 2021 Jun 26;20(6):1897-1899. Epub 2020 Oct 26.

Department of Dermatoloji, Selcuk University Faculty of Medicine, Konya, Turkey.

Delayed pressure urticaria is a rare form of chronic inducible urticaria characterized by erythematous-painful plaques that develop in areas of the skin exposed to prolonged pressure. Its treatment is very difficult, and its response to antihistamines is variable. Cases of delayed pressure urticaria, which have been completely controlled with the use of omalizumab in recent years, have been reported. Read More

View Article and Full-Text PDF

Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review.

J Am Acad Dermatol 2021 Feb 1;84(2):486-494. Epub 2020 Oct 1.

Duke Dermatology, Duke University Medical Center, Durham, North Carolina. Electronic address:

Background: Prolonged wear of facial protective equipment can lead to occupational dermatoses.

Objective: To identify important causes of occupational dermatoses from facial protective equipment.

Methods: A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed using PubMed and Embase databases. Read More

View Article and Full-Text PDF
February 2021

Pressure Urticaria in an Infant Appearing Similar to Physical Abuse.

Pediatrics 2020 10;146(4)

Department of Dermatology, School of Medicine, Boston University, Boston, Massachusetts.

A healthy Hispanic boy was born via cesarean delivery after an uncomplicated pregnancy. At 4 weeks old , his parents brought him to the emergency department for bruising on both soles of the feet. At 6 weeks old, his parents brought him to primary care for new bruises on his arms and back. Read More

View Article and Full-Text PDF
October 2020

Chronic inducible urticaria: classification and prominent features of physical and non-physical types.

Acta Dermatovenerol Alp Pannonica Adriat 2020 Sep;29(3):141-148

Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Chronic inducible urticaria (CIndU) is a common inflammatory skin condition characterized by the recurrence of itchy wheals and/or angioedema that lasts more than 6 weeks and is induced by specific physical or environmental stimuli (cold, heat, exercise, pressure, sunlight, vibration, water, etc.). According to the current international classification, it includes physical urticarias (dermographism, delayed-pressure urticaria, exercise-induced urticaria, cold urticaria, heat urticaria, solar urticaria, and vibratory urticaria) and non-physical urticarias caused by exposure to specific stimuli (cholinergic urticaria, contact urticaria, and aquagenic urticaria). Read More

View Article and Full-Text PDF
September 2020

Early Skin Test after Anaphylaxis during Induction of Anesthesia: A Case Report.

Medicina (Kaunas) 2020 Aug 7;56(8). Epub 2020 Aug 7.

Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital, Kyungheedae Road 23, Dongdaemun-Gu, Seoul 02447, Korea.

Background: It is recommended that a skin test be performed 4-6 weeks after anaphylaxis. However, there is little evidence about the timing of the skin test when there is a need to identify the cause within 4-6 weeks.

Case Report: A 57-year-old woman was scheduled to undergo surgery via a sphenoidal approach to remove a pituitary macroadenoma. Read More

View Article and Full-Text PDF

Vernal Keratoconjunctivitis: A Case of Anti-IgE Treatment with Short-Lasting Remission.

Case Rep Ophthalmol 2020 May-Aug;11(2):268-275. Epub 2020 Jul 3.

Department of Medicine and Science of Ageing, and School of Specialization in Allergy and Clinical Immunology, G. d'Annunzio University, Chieti, Italy.

Vernal keratoconjunctivitis (VKC) is a persistent, severe allergic eye disease, mainly occurring in children, that can lead to severe ocular complications including visual loss. The underlying etiology and pathophysiology of VKC remain unclear. Common therapies include topical antihistamines and mast cell stabilizers that are effective in mild-to-moderate forms of VKC but are often ineffective in severe forms that require topical or systemic corticosteroids. Read More

View Article and Full-Text PDF