539 results match your criteria Urticaria Pressure

Spontaneous abdominal effusion in dogs with presumed anaphylaxis.

J Vet Emerg Crit Care (San Antonio) 2021 Apr 29. Epub 2021 Apr 29.

College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.

Objective: To describe patient characteristics of dogs developing spontaneous abdominal effusion in association with anaphylaxis.

Design: Retrospective study between 2010 and 2018.

Setting: University teaching hospital and referral specialty private practice emergency departments. Read More

View Article and Full-Text PDF

Systemic mastocytosis with flushing and hypotension: A case report and literature review.

Exp Ther Med 2021 Apr 25;21(4):404. Epub 2021 Feb 25.

Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P.R. China.

Systemic mastocytosis (SM) is a heterogeneous disease of the bone marrow, which is characterized by the abnormal proliferation and infiltration of mast cells in one or more organs, such as the skin, bone marrow, digestive tract, liver and spleen. Urticaria pigmentosa is a typical but infrequent manifestation of SM. Other clinical presentations are non-specific, varying from pruritus and hypotension to multiple organ dysfunction, which may be lethal when hemodynamic changes occur, such as the sharp decline in blood pressure observed in the present case. Read More

View Article and Full-Text PDF


Georgian Med News 2020 Dec(309):12-17

3"Center of Innovative Medical Technologies of the National Academy of Sciences of Ukraine".

The aim of the study is to evaluate the tolerability and effectiveness of photodynamic therapy (PDT) of patients with premalignant diseases of the vulva. The study was performed on 10 patients on the basis of the National Cancer Institute of Ukraine (Kyiv). The age of patients ranged from 31 to 67 years old (mean age: 53. Read More

View Article and Full-Text PDF
December 2020

Adverse reactions to radiopharmaceuticals: liver radiopharmaceuticals.

Nucl Med Commun 2021 04;42(4):352-359

Department of Radiopharmacy, Hacettepe University Faculty of Pharmacy, Ankara, Turkey.

Radiopharmaceuticals are radioactive compounds used in nuclear medicine, consisting of a radioactive moiety and a pharmaceutical part. Radiopharmaceuticals are used for diagnosis (predominantly) and therapy (to a lesser extent). Adverse drug reactions are undesirable, unexpected, often harmful drug responses that occur when the drug is administered in therapeutic doses. Read More

View Article and Full-Text PDF

COVID-19 pandemic and the skin: what should dermatologists know?

Clin Dermatol 2020 Nov - Dec;38(6):785-787. Epub 2020 Mar 24.

Department of Dermatology and Venereology, Acibadem City Clinic, Tokuda Hospital, Sofia, Bulgaria.

The world has changed dramatically since the COVID-19 pandemic began. In addition to our social, occupational, and personal lives, the new coronavirus also poses novel challenges for all physicians, including dermatologists. Several skin conditions have emerged, mainly as a result of prolonged contact with personal protective equipment and excessive personal hygiene. Read More

View Article and Full-Text PDF
December 2020

Twice-daily versus once-daily lisinopril and losartan for hypertension: Real-world effectiveness and safety.

PLoS One 2020 3;15(12):e0243371. Epub 2020 Dec 3.

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, United States of America.

Background: Lisinopril and losartan manufacturer labels recommend twice-daily dosing (BID) if once-daily (QDay) is insufficient to lower blood pressure (BP).

Methods And Results: Retrospective cohort study of patients taking QDay lisinopril and losartan who experienced a dose-doubling (index date). A text-processing tool categorized BID and QDay groups at the index date based on administration instructions. Read More

View Article and Full-Text PDF
January 2021

Successful treatment of delayed pressure urticaria with 300 mg of omalizumab every 14 days.

J Cosmet Dermatol 2021 Jun 26;20(6):1897-1899. Epub 2020 Oct 26.

Department of Dermatoloji, Selcuk University Faculty of Medicine, Konya, Turkey.

Delayed pressure urticaria is a rare form of chronic inducible urticaria characterized by erythematous-painful plaques that develop in areas of the skin exposed to prolonged pressure. Its treatment is very difficult, and its response to antihistamines is variable. Cases of delayed pressure urticaria, which have been completely controlled with the use of omalizumab in recent years, have been reported. Read More

View Article and Full-Text PDF

Occupational dermatitis to facial personal protective equipment in health care workers: A systematic review.

J Am Acad Dermatol 2021 Feb 1;84(2):486-494. Epub 2020 Oct 1.

Duke Dermatology, Duke University Medical Center, Durham, North Carolina. Electronic address:

Background: Prolonged wear of facial protective equipment can lead to occupational dermatoses.

Objective: To identify important causes of occupational dermatoses from facial protective equipment.

Methods: A systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed using PubMed and Embase databases. Read More

View Article and Full-Text PDF
February 2021

Pressure Urticaria in an Infant Appearing Similar to Physical Abuse.

Pediatrics 2020 10;146(4)

Department of Dermatology, School of Medicine, Boston University, Boston, Massachusetts.

A healthy Hispanic boy was born via cesarean delivery after an uncomplicated pregnancy. At 4 weeks old , his parents brought him to the emergency department for bruising on both soles of the feet. At 6 weeks old, his parents brought him to primary care for new bruises on his arms and back. Read More

View Article and Full-Text PDF
October 2020

Chronic inducible urticaria: classification and prominent features of physical and non-physical types.

Acta Dermatovenerol Alp Pannonica Adriat 2020 Sep;29(3):141-148

Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Chronic inducible urticaria (CIndU) is a common inflammatory skin condition characterized by the recurrence of itchy wheals and/or angioedema that lasts more than 6 weeks and is induced by specific physical or environmental stimuli (cold, heat, exercise, pressure, sunlight, vibration, water, etc.). According to the current international classification, it includes physical urticarias (dermographism, delayed-pressure urticaria, exercise-induced urticaria, cold urticaria, heat urticaria, solar urticaria, and vibratory urticaria) and non-physical urticarias caused by exposure to specific stimuli (cholinergic urticaria, contact urticaria, and aquagenic urticaria). Read More

View Article and Full-Text PDF
September 2020

Early Skin Test after Anaphylaxis during Induction of Anesthesia: A Case Report.

Medicina (Kaunas) 2020 Aug 7;56(8). Epub 2020 Aug 7.

Department of Anesthesiology and Pain Medicine, Kyung Hee University Hospital, Kyungheedae Road 23, Dongdaemun-Gu, Seoul 02447, Korea.

Background: It is recommended that a skin test be performed 4-6 weeks after anaphylaxis. However, there is little evidence about the timing of the skin test when there is a need to identify the cause within 4-6 weeks.

Case Report: A 57-year-old woman was scheduled to undergo surgery via a sphenoidal approach to remove a pituitary macroadenoma. Read More

View Article and Full-Text PDF

Vernal Keratoconjunctivitis: A Case of Anti-IgE Treatment with Short-Lasting Remission.

Case Rep Ophthalmol 2020 May-Aug;11(2):268-275. Epub 2020 Jul 3.

Department of Medicine and Science of Ageing, and School of Specialization in Allergy and Clinical Immunology, G. d'Annunzio University, Chieti, Italy.

Vernal keratoconjunctivitis (VKC) is a persistent, severe allergic eye disease, mainly occurring in children, that can lead to severe ocular complications including visual loss. The underlying etiology and pathophysiology of VKC remain unclear. Common therapies include topical antihistamines and mast cell stabilizers that are effective in mild-to-moderate forms of VKC but are often ineffective in severe forms that require topical or systemic corticosteroids. Read More

View Article and Full-Text PDF

COVID-19 and dermatology

Ülker Gül

Turk J Med Sci 2020 12 17;50(8):1751-1759. Epub 2020 Dec 17.

Department of Dermatology, Gülhane Faculty of Medicine, Health Sciences University, İstanbul, Turkey

Background/aim: Sars-CoV-2 virus infection (COVID-19) was observed in China in the last months of 2019. In the period following, this infection spread all over the world. In March 2020 the World Health Organization announced the existence of a pandemic. Read More

View Article and Full-Text PDF
December 2020

Acquired angioedema induced by angiotensin-converting enzyme inhibitors - experience of a hospital-based allergy center.

Exp Ther Med 2020 Jul 27;20(1):68-72. Epub 2020 Jan 27.

Dermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Angiotensin-converting enzyme inhibitors (ACEIs) represent an important group of pharmacological compounds, largely prescribed for more than 30 years. They have been extensively evaluated in clinical trials, demonstrating significant reduction of morbidity and mortality of patients with cardiovascular diseases, mainly high blood pressure, myocardial infarction, heart failure and stroke. Besides their beneficial effects and a general good safety profile, it was proven that ACEIs might also induce adverse effects in some patients, most notably angioedema (AE) and chronic cough. Read More

View Article and Full-Text PDF

Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome.

Elife 2020 04 27;9. Epub 2020 Apr 27.

Intensive Care, Radboudumc Center for Infectious Diseases (RCI), Radboudumc, Nijmegen, Netherlands.

COVID-19 patients can present with pulmonary edema early in disease. We propose that this is due to a local vascular problem because of activation of bradykinin 1 receptor (B1R) and B2R on endothelial cells in the lungs. SARS-CoV-2 enters the cell via ACE2 that next to its role in RAAS is needed to inactivate des-Arg9 bradykinin, the potent ligand of the B1R. Read More

View Article and Full-Text PDF

Delayed Pressure Urticaria: A Systematic Review of Treatment Options.

J Allergy Clin Immunol Pract 2020 06 13;8(6):2035-2049.e5. Epub 2020 Mar 13.

Dermatological Allergology, Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

Background: Delayed pressure urticaria (DPU) is characterized by recurrent erythematous and often painful swelling after the skin is exposed to sustained pressure. Treatment is challenging. Antihistamines, the first-line and only approved treatment, are often not effective. Read More

View Article and Full-Text PDF

An Urticarial Primer.

S D Med 2019 Dec;72(12):556-560

Dakota Asthma and Allergy, Sioux Falls, South Dakota.

This primer focuses on the diagnosis and treatment of urticaria. All forms have in common the release of histamine with resultant pruritis. Causes include allergies, medications, infections, cold, heat, and pressure with many being defined as idiopathic. Read More

View Article and Full-Text PDF
December 2019

Recalcitrant, delayed pressure urticaria treated with long-term intravenous immunoglobulin.

JAAD Case Rep 2020 Mar 18;6(3):176-177. Epub 2020 Feb 18.

Department of Dermatology, Henry Ford Hospital, Detroit, Michigan.

View Article and Full-Text PDF

Evaluation of retinal microvascular perfusion in hereditary angioedema: a case-control study.

Orphanet J Rare Dis 2020 01 17;15(1):20. Epub 2020 Jan 17.

Rheumatology, Allergology and Clinical Immunology, Department of "Medicina dei Sistemi", University of Rome Tor Vergata, Rome, Italy.

Evidence supports that hereditary angioedema (HAE) may be considered as a paroxysmal permeability disorder with defective but self-limiting endothelial barrier dysfunction. A potential subclinical abnormal vascular permeability at retinal capillaries could induce damage resulting in retinopathy. We aimed at exploring for the first time the presence of microangiopathy at retinal level from a highly selective cohort of patients with HAE due to C1 esterase inhibitor protein (C1INH) deficiency (type I). Read More

View Article and Full-Text PDF
January 2020

Dermatographism and urticaria in a pediatric population.

Pediatr Allergy Immunol 2020 04 23;31(3):318-320. Epub 2020 Jan 23.

Allergy Unit, Department of pediatrics, Anna Meyer Children's University Hospital, Florence, Italy.

View Article and Full-Text PDF

Simultaneous acute pancreatitis and angioedema associated with angiotensin-converting enzyme inhibitor.

Saudi J Kidney Dis Transpl 2019 Nov-Dec;30(6):1479-1484

Department of Medicine A, Charles Nicolle Hospital; Faculty of Medicine, Tunis El Manar University; Laboratory of Research in Immunology of Renal Transplantation and Immunopathology (LR03SP01), Charles Nicolle Hospital, Tunis, Tunisia.

Angiotensin-converting enzyme inhibitors (ACEI) are commonly prescribed drugs for blood pressure (BP) control and renal protection. The use of ACEI is not associated with an increased risk of acute pancreatitis and ACEI-induced angioedema is rare. A 36-year-old woman presented with vomiting, headache, and aphasia. Read More

View Article and Full-Text PDF

Genetic susceptibility to angiotensin-converting enzyme-inhibitor induced angioedema: A systematic review and evaluation of methodological approaches.

PLoS One 2019 11;14(11):e0224858. Epub 2019 Nov 11.

Department of Oto-Rhino-Laryngology-Head and Neck Surgery and Audiology, Denmark.

Angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II which causes vasoconstriction. ACE inhibitors reduce blood pressure by inhibiting ACE. A well-known adverse drug reaction to ACE inhibitors is ACE inhibitor-induced angioedema (ACEi-AE). Read More

View Article and Full-Text PDF

Urticaria and angioedema.

Allergy Asthma Proc 2019 11;40(6):437-440

Urticaria, also known as hives, may affect up to 20% of the population at some time. Urticaria is described as pruritic erythematous, raised, circumscribed lesions with central pallor that blanch with pressure. Urticaria is closely associated with angioedema in 40% of individuals; approximately 10% of patients experience angioedema without urticaria. Read More

View Article and Full-Text PDF
November 2019

Orolingual Angioedema After Tissue Plasminogen Activator Administration in Patients Taking Angiotensin-Converting Enzyme Inhibitors.

Adv Emerg Nurs J 2019 Jul/Sep;41(3):204-214

Department of Pharmacy, University of Louisville Hospital, Kentucky.

Orolingual angioedema is a rare adverse effect (1%-5%) of tissue plasminogen activator (tPA) that can lead to significant morbidity in patients with acute ischemic stroke. It is thought that increased levels of bradykinin and histamine resulting from tPA administration can result in angioedema. Angiotensin-converting enzyme (ACE) inhibitors can also lead to increased levels of bradykinin and appear to be a risk factor for tPA-associated angioedema. Read More

View Article and Full-Text PDF
January 2020

Treatment of urticaria: a clinical and mechanistic approach.

Allen P Kaplan

Curr Opin Allergy Clin Immunol 2019 08;19(4):387-392

Department Medicine, The Medical University of South Carolina, Charleston, South Carolina, USA.

Purpose Of Review: This manuscript describes the recommended therapy of chronic spontaneous urticaria based on our understanding of the pathogenesis of hive formation. Thus, the mechanism of action of each medication is elaborated in addition to a discussion of clinical utility.

Recent Findings: The main drugs are antihistamines, omalizumab, and cyclosporine with a success rate of 40-55, 65-80, and 70-80%, respectively. Read More

View Article and Full-Text PDF

Flow-mediated dilation shows impaired endothelial function in patients with mastocytosis.

J Allergy Clin Immunol 2019 10 15;144(4):1106-1111. Epub 2019 Jun 15.

Division of Allergy and Clinical Immunology, Department of Medicine, University of Salerno, Salerno, Italy. Electronic address:

Background: Mastocytosis is a rare disease characterized by clonal proliferation of mast cells (MCs) in different organs. Clinical manifestations of mastocytosis are mostly due to release of mediators from MCs and, in many cases, such as urticaria, flushing, angioedema, and anaphylaxis, are an expression of the biological effects of mediators on endothelial cells. Chronic secretion of mediators in patients with mastocytosis can lead to alteration of endothelial function. Read More

View Article and Full-Text PDF
October 2019

Angioedema in Stroke Patients With Thrombolysis.

Stroke 2019 07 11;50(7):1682-1687. Epub 2019 Jun 11.

From the Department of Neurology (K.F., K.M., S.T.G., T.B., M.J.H., S.S., F.S., B.K., K.W.), University Hospital Erlangen, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg, Germany.

Background and Purpose- Oral angioedema (OA) is a rare but life-threatening complication in patients with ischemic stroke receiving intravenous thrombolysis with r-tPA (recombinant tissue-type plasminogen activator). This study intended to determine associations between thrombolysis-related OA and ischemic stroke lesion sites using a voxel-wise lesion analysis. Methods- Prospective registry data were used to identify ischemic stroke patients with thrombolysis-related OA between 2002 and 2018. Read More

View Article and Full-Text PDF

An unexpected challenging airway: Urticaria factitia caused difficult mask ventilation and tracheal intubation.

J Clin Anesth 2019 Nov 10;57:116. Epub 2019 Apr 10.

Duzce University Faculty of Medicine, Neurosurgery Department, Duzce, Turkey.

View Article and Full-Text PDF
November 2019

[Anaphylactic shock secondary to the use of macrogol 4000 as a bowel cleanser:a case report].

Nihon Shokakibyo Gakkai Zasshi 2019 ;116(4):330-335

Department of Gastroenterology and Hepatology, Itami City Hospital.

A 44-year-old man was administered Niflec containing macrogol 4000 as a bowel cleanser for colonoscopic examination. Immediately after ingestion, he experienced oral cavity discomfort and nasal congestion, followed by acute urticaria and presyncope. His systolic blood pressure and peripheral capillary oxygen saturation dropped to 66mmHg and 89%, respectively. Read More

View Article and Full-Text PDF