196 results match your criteria Urticaria Dermographism


[Cold urticaria with risk of anaphylaxis treated with omalizumab. A case report].

Rev Alerg Mex 2020 Oct-Dec;67(4):408-412

Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Servicio de Alergia e Inmuno-logía Clínica, Jalisco, México.

Background: Omalizumab, which is a monoclonal anti-IgE antibody, has recently been used as an option in the treatment of inducible urticaria.

Case Report: We describe the case of a 46-year-old woman who was referred to the Department of Allergy and Immunology of "Hospital Civil de Guadalajara, Dr. Juan I. Read More

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February 2021

Prevalence of Chronic Inducible Urticaria in Elderly Patients.

J Clin Med 2021 Jan 12;10(2). Epub 2021 Jan 12.

Department of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.

Background: No data currently exist regarding the epidemiology of chronic inducible urticarias (CIndUs) in the ≥65-year-old population.

Objective: The study aimed to determine the prevalence of CIndUs among elderly patients affected by chronic urticaria (CU).

Methods: The medical records of all patients referred to us with a diagnosis of CU from January 2008 to September 2020 were retrospectively reviewed, and the patients with CIndUs were identified. Read More

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January 2021

miR-126-3p and miR-16-5p as novel serum biomarkers for disease activity and treatment response in symptomatic dermographism.

Clin Immunol 2021 01 29;222:108636. Epub 2020 Nov 29.

Department of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China. Electronic address:

Symptomatic dermographism (SD) is the most common form of physical urticaria. So far no promising serum biomarkers for SD have been reported. Recently, microRNAs (miRNAs) have been reported to be serum biomarkers for chronic spontaneous urticaria. Read More

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January 2021

Pressure Urticaria in an Infant Appearing Similar to Physical Abuse.

Pediatrics 2020 10;146(4)

Department of Dermatology, School of Medicine, Boston University, Boston, Massachusetts.

A healthy Hispanic boy was born via cesarean delivery after an uncomplicated pregnancy. At 4 weeks old , his parents brought him to the emergency department for bruising on both soles of the feet. At 6 weeks old, his parents brought him to primary care for new bruises on his arms and back. Read More

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October 2020

Chronic inducible urticaria: classification and prominent features of physical and non-physical types.

Acta Dermatovenerol Alp Pannonica Adriat 2020 Sep;29(3):141-148

Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Chronic inducible urticaria (CIndU) is a common inflammatory skin condition characterized by the recurrence of itchy wheals and/or angioedema that lasts more than 6 weeks and is induced by specific physical or environmental stimuli (cold, heat, exercise, pressure, sunlight, vibration, water, etc.). According to the current international classification, it includes physical urticarias (dermographism, delayed-pressure urticaria, exercise-induced urticaria, cold urticaria, heat urticaria, solar urticaria, and vibratory urticaria) and non-physical urticarias caused by exposure to specific stimuli (cholinergic urticaria, contact urticaria, and aquagenic urticaria). Read More

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September 2020

Successful treatment of symptomatic dermographism in an adolescent with omalizumab.

Dermatol Ther 2020 11 28;33(6):e14304. Epub 2020 Sep 28.

Faculty of Medicine, Department of Dermatology, Eskisehir Osmangazi University, Eskisehir, Turkey.

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November 2020

Chronic inducible urticaria subtypes in children: Clinical features and prognosis.

Pediatr Allergy Immunol 2021 01 24;32(1):146-152. Epub 2020 Aug 24.

Department of Pediatric Allergy, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: Chronic inducible urticaria (CIndU) is a subtype of chronic urticaria induced by a physical stimulus.

Objective: To evaluate the clinical features, prognostic factors, and natural course of childhood CIndU subtypes.

Methods: Patients (1-18 years old, n = 117) diagnosed with CIndU between March 2011 and March 2019 were analyzed. Read More

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January 2021

Symptomatic Dermographism: A Systematic Review of Treatment Options.

J Allergy Clin Immunol Pract 2020 10 28;8(9):3141-3161. Epub 2020 May 28.

Dermatological Allergology, Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

Background: Symptomatic dermographism (SD), the most common form of chronic inducible urticaria, presents with transient wheals accompanied by itching in response to scratching. Little is known about available treatment options and their efficacy in SD.

Objective: To systematically review the efficacy of treatment options for patients with SD. Read More

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October 2020

Natural History of Chronic Urticaria in Korea.

Ann Dermatol 2020 Feb 27;32(1):38-46. Epub 2019 Dec 27.

Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea.

Background: Data on the natural history and prognostic variables of chronic urticaria (CU) are rare and information about spontaneous remission of CU is limited.

Objective: This study evaluated the natural history of CU and identified predictors for remission.

Methods: Total 329 Korean patients with CU, who had follow-ups more than 6 months after diagnosis during a 7-year period in the department of dermatology in three university hospitals were enrolled. Read More

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February 2020

Management problems in severe chronic inducible urticaria: Two case reports.

Exp Ther Med 2019 Aug 10;18(2):960-963. Epub 2019 Jun 10.

Allergology Outpatient Clinic, The Clinical Emergency Hospital for Children 'M.S. Curie', 041434 Bucharest, Romania.

Chronic inducible urticaria (CIndU) is a subgroup of chronic urticaria which can cause severe quality of life impairment by their refractory forms. The recommended treatment approach in CindU is the same as that for chronic spontaneous urticaria (CSU). However, CIndU seem to be more resistant to standard doses of H1 antihistamines (AHs) and higher doses of AHs are required for symptom control. Read More

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Benefit of benralizumab treatment in a patient with chronic symptomatic dermographism.

J Eur Acad Dermatol Venereol 2019 Nov 18;33(11):e413-e415. Epub 2019 Jun 18.

Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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November 2019

Fric Test Revisited: A Suggestion for a New Scoring System and Its Correlation with Urticaria Control Test and Dermatology Life Quality Index.

Int Arch Allergy Immunol 2019;178(1):76-82. Epub 2018 Oct 4.

Background: Fric test is a useful tool for the diagnosis and threshold testing for symptomatic dermographism. When threshold testing is not available, Urticaria Control Test (UCT) and Dermatology Life Quality Index (DLQI) might be used to assess disease control and quality of life (QoL) impairment, respectively.

Objectives: In this study, we aimed to describe a new scoring system for the Fric test and evaluate the correlations of Fric scores with UCT, DLQI, and other disease activity assessment scores. Read More

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How to Approach Chronic Inducible Urticaria.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1119-1130

Division of Allergy and Immunology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex.

Chronic inducible urticaria (CIndU) is a group of chronic urticarias characterized by the appearance of recurrent wheals, recurrent angioedema or both, as a response to specific triggers. CIndU includes both physical (symptomatic dermographism, cold and heat urticaria, delayed pressure urticaria, solar urticaria, and vibratory urticaria) and nonphysical urticarias (cholinergic urticaria, contact and aquagenic urticaria). Here, we review the different forms of CIndU with an emphasis on symptomatic dermographism, cold urticaria, cholinergic urticaria, and delayed pressure urticaria. Read More

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October 2019

Natural course and prognostic factors of chronic urticaria in Korean children: A single center experience.

Asian Pac J Allergy Immunol 2019 Mar;37(1):19-24

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Chronic urticaria (CU) has an adverse effect on academic achievement and psychosocial development in children.

Objective: We aimed to investigate the natural course of CU and to identify relevant factors associated with a poor CU prognosis in Korean children.

Methods: We retrospectively analyzed 253 children with episodes of wheals or angioedema at least 3 times a week that persisted for at least 6 weeks. Read More

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Epidemiology of urticaria including physical urticaria and angioedema in Korea.

Korean J Intern Med 2019 Mar 11;34(2):418-425. Epub 2018 May 11.

Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea.

Background/aims: Despite the high burden and frequency of urticaria, its epidemiology is not well known. We investigated the epidemiology of various type of urticaria in Korea and changes in its annual prevalence over 5 years.

Methods: We used data from the 2010 to 2014 Health Insurance Review and Assessment database, which covers the claims of 97. Read More

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Chronic inducible urticaria: A systematic review of treatment options.

J Allergy Clin Immunol 2018 05 10;141(5):1726-1734. Epub 2018 Feb 10.

Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address:

Background: Chronic inducible urticaria (CindU) is a condition characterized by the appearance of recurrent wheals, angioedema, or both as a response to specific and reproducible triggers.

Objective: We sought to systematically assess evidence on the efficacy and safety of treatment options for CindU. Results were used to inform the 2017 update of "The EAACI/GALEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Read More

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Chronic inducible urticarias in children.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1391-1393. Epub 2018 Feb 14.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

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November 2019

Etiology of chronic urticaria: the Ecuadorian experience.

World Allergy Organ J 2018 3;11(1). Epub 2018 Jan 3.

Universidad Espíritu Santo, Km. 2.5 vía La Puntilla, Código postal: 0901-952 Samborondón, Ecuador.

Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its treatment.

Methods: We performed a retrospective study involving 112 patients diagnosed with CU using a Checklist for a complete chronic urticaria medical history. Read More

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January 2018

Rational ideation and empiric validation of an innovative digital dermographic tester.

Clin Exp Dermatol 2018 Apr 22;43(3):268-273. Epub 2017 Dec 22.

Department of Medicine, Surgery and Odontology Scuola Medica Salernitana, University of Salerno, Salerno, Italy.

Background: Dermographism is a condition characterized by a weal response to a combination of pressure and traction on skin surface, and its diagnosis is based on medical history, clinical criteria and provocation test. The Dermographic Tester , a pen-sized tool containing a spring-loaded blunt tip, is the most widely used instrument for the provocation test, and it exerts increasing pressures on the skin surface according to an arbitrary units (AU) scale. Analysing the mechanism of function and trying to convert the AUs to SI units (g/mm ), we found that this instrument had some defects and limits that would compromise a true and repeatable quantification of the weal response threshold. Read More

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Dermographism in a patient with fever.

Int J Dermatol 2018 Jan 19;57(1):19-20. Epub 2017 Oct 19.

Department of Dermatology, Hospital Clínic, Universitat de Barcelona, Barcelona, Spain.

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January 2018

Brain-derived neurotrophic factor is increased in serum levels of patients with symptomatic dermographism.

Postepy Dermatol Alergol 2017 Aug 2;34(4):346-349. Epub 2017 Aug 2.

Division of Allergy, Department of Chest Medicine, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey.

Introduction: Symptomatic dermographism (SD) is the most common form of physical urticaria. However, the role of neuroimmune mechanisms in SD is unclear.

Aim: To investigate circulating levels of brain-derived neurotrophic factor (BDNF) in symptomatic dermographism. Read More

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Omalizumab treatment in patients with chronic inducible urticaria: A systematic review of published evidence.

J Allergy Clin Immunol 2018 02 24;141(2):638-649. Epub 2017 Jul 24.

Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Background: Omalizumab, a recombinant anti-IgE antibody, effectively treats chronic spontaneous urticaria. Evidence is lacking in patients with chronic inducible urticarias (CIndUs), which are frequently H-antihistamine resistant.

Objective: From the current published literature, we aimed to determine the strength of evidence for omalizumab efficacy and safety in the treatment of CIndUs. Read More

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February 2018

Review of Physical Urticarias and Testing Methods.

Curr Allergy Asthma Rep 2017 Aug;17(8):51

Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.

Purpose Of Review: This review aims to update the information available on the prevalence, clinical picture, diagnostic methods, and treatment of urticarias induced by external physical stimuli.

Recent Findings: Physical urticarias are present in up to 5% of the general population, and in 10 to 50% of patients with chronic urticaria. Recent investigations have provided evidence that the presence of physical urticaria alone or when comorbid with chronic spontaneous urticaria is associated with a worse prognosis and duration. Read More

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Omalizumab is effective in symptomatic dermographism-results of a randomized placebo-controlled trial.

J Allergy Clin Immunol 2017 09 4;140(3):870-873.e5. Epub 2017 Apr 4.

Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

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September 2017

Black Dermographism.

Authors:
Erin Lowe Scott Lim

JAMA Dermatol 2017 03;153(3):352-353

Scott Lim, DO, LLC, Erie, Pennsylvania.

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Clinical and etiologic evaluation of the children with chronic urticaria.

Allergy Asthma Proc 2016 11;37(6):450-457

Pediatric Allergy and Immunology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

Background: Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for 6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU).

Objectives: To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification. Read More

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November 2016

Prevalence of Inducible Urticaria in Patients with Chronic Spontaneous Urticaria: Associated Risk Factors.

J Allergy Clin Immunol Pract 2017 Mar - Apr;5(2):464-470. Epub 2016 Nov 9.

Group of Experimental and Clinical Allergy, IPS Universitaria, University of Antioquia, Medellín, Colombia.

Background: Information on the prevalence of inducible urticaria (IU) in patients with chronic spontaneous urticaria (CSU) and the factors affecting this prevalence is scarce in the literature.

Objectives: To estimate the frequency of IU in patients with CSU and to explore possible factors associated with CSU.

Methods: Patients older than 12 years diagnosed with CSU and a control group with no history of urticaria were recruited from 2 different cities. Read More

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November 2017

Inducible urticaria: Case series and literature review.

Biomedica 2016 Mar 3;36(1):10-21. Epub 2016 Mar 3.

Grupo de Alergología Clínica y Experimental (GACE), IPS Universitaria, Universidad de Antioquia, Medellín, Colombia.

Inducible urticaria is a heterogeneous group of skin disorders characterized by the appearance of wheals, pruritus and/or angioedema, sometimes accompanied by systemic symptoms caused by innocuous stimuli (cold, heat, pressure, etc.). This group of disorders compromises people's quality of life and most of the literature in this regard comes from case reports and case series since its epidemiology has been poorly studied and some cases are very rare. Read More

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Basophil CD63 expression in chronic spontaneous urticaria: correlation with allergic sensitization, serum autoreactivity and basophil reactivity.

J Eur Acad Dermatol Venereol 2017 Mar 5;31(3):463-468. Epub 2016 Sep 5.

Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China.

Background: The underlying causes and factors contributing to the disease severity of chronic spontaneous urticaria (CSU) are unknown.

Objective: Given the important role of basophils in the pathogenesis of urticaria and that CD63 serves as a useful marker for basophil activation and detecting, CD63 expression of basophils is a reliable tool for diagnosing allergy and hypersensitivity reactions to different allergens; the objective of this study was to investigate whether the level of basophil CD63 expression is correlated with allergen sensitization, serum autoreactivity and basophil reactivity in patients with CSU.

Methods: Basophil-enriched leucocytes were separated from the blood of 64 patients with chronic urticaria (54 CSU patients and 10 symptomatic dermographism patients), 18 healthy control subjects and seven atopic donors without urticaria. Read More

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