208 results match your criteria Urticaria Dermographism


An open-label, proof-of-concept study of lirentelimab for antihistamine-resistant chronic spontaneous and inducible urticaria.

J Allergy Clin Immunol 2022 May 23;149(5):1683-1690.e7. Epub 2021 Dec 23.

Dermatologial Allergology, Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany; Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany; Berlin Institute of Health, Berlin, Germany. Electronic address:

Background: Chronic urticaria (CU) is a debilitating mast cell-driven disease, often refractory to standard therapy (ie, antihistamines). Lirentelimab, an anti-sialic acid-binding immunoglobulin-like lectin 8 mAb, selectively inhibits mast cells and depletes eosinophils.

Objective: We sought to determine safety and efficacy of lirentelimab in patients with CU. Read More

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Excitement-Induced Cutaneous Bleeding (Haematidrosis-like) in a Dog.

Vet Sci 2021 Dec 13;8(12). Epub 2021 Dec 13.

Clinic of Medicine, Faculty of Veterinary Science, University of Thessaly, Trikalon Str. 224, GR-43132 Karditsa, Greece.

A 15-month-old intact female Pitbull was referred because of recurrent, episodic, self-limiting, excitement-induced bleeding from nontraumatised skin. No abnormalities were detected upon physical examination. Subsequently, the dog went for a walk under the direct supervision of one of the authors, became overexcited and, after approximately five minutes, bloody liquid, with a patchy distribution, appeared along the hair shafts of the face and neck. Read More

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December 2021

An evaluation of the factors affecting the clinical and laboratory findings, prognosis, and treatment response in children with chronic urticaria.

Dermatol Ther 2022 03 21;35(3):e15261. Epub 2021 Dec 21.

Department of Pediatrics, University of Health Sciences Tepecik Training and Research Hospital, Izmir, Turkey.

Chronic urticaria (CU) is a rare disease in childhood, and studies in children are limited. In this study, the aim was to investigate the clinical and laboratory findings and demographic characteristics of children with CU and to determine the factors affecting prognosis. The study included 141 patients aged 0-18 years who were diagnosed with CU in the pediatric allergy outpatient clinic between January 1, 2013, and December 31, 2018. Read More

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Biomarkers of Gut Microbiota in Chronic Spontaneous Urticaria and Symptomatic Dermographism.

Front Cell Infect Microbiol 2021 9;11:703126. Epub 2021 Nov 9.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Background: Chronic urticaria (CU) is a chronic inflammatory skin disease associated with Th2 immune response. The two most common subtypes of CU, i.e. Read More

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January 2022

Chronic Spontaneous and Inducible Urticaria Associated With Mycoplasma pneumoniae Infection.

Cureus 2021 Oct 13;13(10):e18746. Epub 2021 Oct 13.

Department of Allergy and Clinical Immunology, 424 General Military Training Hospital, Thessaloniki, GRC.

Acute childhood urticaria is a common disorder that has been associated with infections. In a few children, it may last for more than six weeks, thereafter it is characterized as chronic urticaria (CU). We report two cases, one suffering from chronic spontaneous urticaria and one chronic inducible urticarias (dermographism and cold urticaria). Read More

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October 2021

Glove-related hand urticaria.

Tidsskr Nor Laegeforen 2021 10 11;141(2021-14). Epub 2021 Oct 11.

Background: Glove-related hand urticaria is probably underdiagnosed and is an important differential diagnosis in suspected cases of contact allergy.

Case Presentation: A nurse in her twenties presented with recurrent immediate-onset erythematous eruption with burning sensation on the dorsal hands after wearing disposable gloves. This occurred irrespective of the type of disposable gloves used. Read More

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October 2021

Symptomatic dermographism in Chinese population: an epidemiological study of hospital-based multicenter questionnaire survey.

Curr Med Res Opin 2022 01 24;38(1):131-137. Epub 2021 Nov 24.

Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Objective: There are few epidemiological studies on SD in China. This study aims to clarify the epidemic distribution characteristics of SD in China and provide ideas and clues for the prevention and treatment of the disease.

Methods: The cross-sectional study was conducted in 2019 based on the hospital's epidemiological questionnaire. Read More

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January 2022

Clinical difference between single subtype and mixed subtype chronic urticaria: A retrospective study.

Indian J Dermatol Venereol Leprol 2022 Mar-Apr;88(2):171-176

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Background: The subtypes of chronic urticaria share a common clinical expression, but may show differences phenotypically. Meanwhile, two or more different subtypes of chronic urticaria can coexist in any given patient which may involve different phenotypes.

Aims: The study aims to compare the two phenotypes in terms of demographics, clinical profile and treatment response. Read More

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Food-dependent and food-exacerbated symptomatic dermographism: New variants of symptomatic dermographism.

J Allergy Clin Immunol 2022 02 8;149(2):788-790. Epub 2021 Aug 8.

Urticaria Center of Reference and Excellence (UCARE), Dermatological Allergology, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Background: Symptomatic dermographism (SD) is the most common form of chronic inducible urticaria. The criterion standard for diagnosing SD and disease activity assessment in SD is provocation testing. As of now, if and what cofactors have an impact on provocation test results is unknown. Read More

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February 2022

Dermographism in COVID-19.

BMJ Case Rep 2021 Jun 23;14(6). Epub 2021 Jun 23.

Department of Medicine, University of Florida Health, Gainesville, Florida, USA

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[White dermographism as an atypical cutaneous manifestation of COVID-19].

Semergen 2021 10 27;47(7):e55-e56. Epub 2021 Apr 27.

Servicio de Medicina Preventiva y Salud Pública, Hospital Vital Álvarez Buylla, Mieres, Asturias, España. Electronic address:

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October 2021

Identification of gut microbiota signatures in symptomatic dermographism.

Exp Dermatol 2021 12 22;30(12):1794-1799. Epub 2021 Mar 22.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China.

Symptomatic dermographism (SD) is a recurrent inflammatory skin disease related to immunity; however, the details remain elusive. In view of the important role of gut microbiota in immune regulation, the purpose of this study is to investigate the alterations of gut microbiota in SD and explore the potential bacterial biomarkers for diagnosis. A case-control study including SD patients and normal controls (NCs) was carried out. Read More

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December 2021

[Cold urticaria with risk of anaphylaxis treated with omalizumab. A case report].

Rev Alerg Mex 2020 Oct-Dec;67(4):408-412

Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Servicio de Alergia e Inmuno-logía Clínica, Jalisco, México.

Background: Omalizumab, which is a monoclonal anti-IgE antibody, has recently been used as an option in the treatment of inducible urticaria.

Case Report: We describe the case of a 46-year-old woman who was referred to the Department of Allergy and Immunology of "Hospital Civil de Guadalajara, Dr. Juan I. Read More

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October 2021

Prevalence of Chronic Inducible Urticaria in Elderly Patients.

J Clin Med 2021 Jan 12;10(2). Epub 2021 Jan 12.

Department of Health Sciences, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.

Background: No data currently exist regarding the epidemiology of chronic inducible urticarias (CIndUs) in the ≥65-year-old population.

Objective: The study aimed to determine the prevalence of CIndUs among elderly patients affected by chronic urticaria (CU).

Methods: The medical records of all patients referred to us with a diagnosis of CU from January 2008 to September 2020 were retrospectively reviewed, and the patients with CIndUs were identified. Read More

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January 2021

miR-126-3p and miR-16-5p as novel serum biomarkers for disease activity and treatment response in symptomatic dermographism.

Clin Immunol 2021 01 29;222:108636. Epub 2020 Nov 29.

Department of Dermatology, The First Hospital of China Medical University, National Health Commission Key Laboratory of Immunodermatology, Key Laboratory of Immunodermatology of Ministry of Education, Shenyang, China. Electronic address:

Symptomatic dermographism (SD) is the most common form of physical urticaria. So far no promising serum biomarkers for SD have been reported. Recently, microRNAs (miRNAs) have been reported to be serum biomarkers for chronic spontaneous urticaria. Read More

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January 2021

Pressure Urticaria in an Infant Appearing Similar to Physical Abuse.

Pediatrics 2020 10;146(4)

Department of Dermatology, School of Medicine, Boston University, Boston, Massachusetts.

A healthy Hispanic boy was born via cesarean delivery after an uncomplicated pregnancy. At 4 weeks old , his parents brought him to the emergency department for bruising on both soles of the feet. At 6 weeks old, his parents brought him to primary care for new bruises on his arms and back. Read More

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October 2020

Chronic inducible urticaria: classification and prominent features of physical and non-physical types.

Acta Dermatovenerol Alp Pannonica Adriat 2020 Sep;29(3):141-148

Clinical Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Chronic inducible urticaria (CIndU) is a common inflammatory skin condition characterized by the recurrence of itchy wheals and/or angioedema that lasts more than 6 weeks and is induced by specific physical or environmental stimuli (cold, heat, exercise, pressure, sunlight, vibration, water, etc.). According to the current international classification, it includes physical urticarias (dermographism, delayed-pressure urticaria, exercise-induced urticaria, cold urticaria, heat urticaria, solar urticaria, and vibratory urticaria) and non-physical urticarias caused by exposure to specific stimuli (cholinergic urticaria, contact urticaria, and aquagenic urticaria). Read More

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September 2020

Successful treatment of symptomatic dermographism in an adolescent with omalizumab.

Dermatol Ther 2020 11 28;33(6):e14304. Epub 2020 Sep 28.

Faculty of Medicine, Department of Dermatology, Eskisehir Osmangazi University, Eskisehir, Turkey.

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November 2020

Chronic inducible urticaria subtypes in children: Clinical features and prognosis.

Pediatr Allergy Immunol 2021 01 24;32(1):146-152. Epub 2020 Aug 24.

Department of Pediatric Allergy, Hacettepe University Faculty of Medicine, Ankara, Turkey.

Background: Chronic inducible urticaria (CIndU) is a subtype of chronic urticaria induced by a physical stimulus.

Objective: To evaluate the clinical features, prognostic factors, and natural course of childhood CIndU subtypes.

Methods: Patients (1-18 years old, n = 117) diagnosed with CIndU between March 2011 and March 2019 were analyzed. Read More

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January 2021

Symptomatic Dermographism: A Systematic Review of Treatment Options.

J Allergy Clin Immunol Pract 2020 10 28;8(9):3141-3161. Epub 2020 May 28.

Dermatological Allergology, Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

Background: Symptomatic dermographism (SD), the most common form of chronic inducible urticaria, presents with transient wheals accompanied by itching in response to scratching. Little is known about available treatment options and their efficacy in SD.

Objective: To systematically review the efficacy of treatment options for patients with SD. Read More

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October 2020

Natural History of Chronic Urticaria in Korea.

Ann Dermatol 2020 Feb 27;32(1):38-46. Epub 2019 Dec 27.

Department of Dermatology, College of Medicine, Hallym University, Seoul, Korea.

Background: Data on the natural history and prognostic variables of chronic urticaria (CU) are rare and information about spontaneous remission of CU is limited.

Objective: This study evaluated the natural history of CU and identified predictors for remission.

Methods: Total 329 Korean patients with CU, who had follow-ups more than 6 months after diagnosis during a 7-year period in the department of dermatology in three university hospitals were enrolled. Read More

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February 2020

Management problems in severe chronic inducible urticaria: Two case reports.

Exp Ther Med 2019 Aug 10;18(2):960-963. Epub 2019 Jun 10.

Allergology Outpatient Clinic, The Clinical Emergency Hospital for Children 'M.S. Curie', 041434 Bucharest, Romania.

Chronic inducible urticaria (CIndU) is a subgroup of chronic urticaria which can cause severe quality of life impairment by their refractory forms. The recommended treatment approach in CindU is the same as that for chronic spontaneous urticaria (CSU). However, CIndU seem to be more resistant to standard doses of H1 antihistamines (AHs) and higher doses of AHs are required for symptom control. Read More

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Benefit of benralizumab treatment in a patient with chronic symptomatic dermographism.

J Eur Acad Dermatol Venereol 2019 Nov 18;33(11):e413-e415. Epub 2019 Jun 18.

Allergie-Centrum-Charité, Department of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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November 2019

Fric Test Revisited: A Suggestion for a New Scoring System and Its Correlation with Urticaria Control Test and Dermatology Life Quality Index.

Int Arch Allergy Immunol 2019;178(1):76-82. Epub 2018 Oct 4.

Background: Fric test is a useful tool for the diagnosis and threshold testing for symptomatic dermographism. When threshold testing is not available, Urticaria Control Test (UCT) and Dermatology Life Quality Index (DLQI) might be used to assess disease control and quality of life (QoL) impairment, respectively.

Objectives: In this study, we aimed to describe a new scoring system for the Fric test and evaluate the correlations of Fric scores with UCT, DLQI, and other disease activity assessment scores. Read More

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How to Approach Chronic Inducible Urticaria.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1119-1130

Division of Allergy and Immunology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Tex.

Chronic inducible urticaria (CIndU) is a group of chronic urticarias characterized by the appearance of recurrent wheals, recurrent angioedema or both, as a response to specific triggers. CIndU includes both physical (symptomatic dermographism, cold and heat urticaria, delayed pressure urticaria, solar urticaria, and vibratory urticaria) and nonphysical urticarias (cholinergic urticaria, contact and aquagenic urticaria). Here, we review the different forms of CIndU with an emphasis on symptomatic dermographism, cold urticaria, cholinergic urticaria, and delayed pressure urticaria. Read More

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October 2019

Natural course and prognostic factors of chronic urticaria in Korean children: A single center experience.

Asian Pac J Allergy Immunol 2019 Mar;37(1):19-24

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: Chronic urticaria (CU) has an adverse effect on academic achievement and psychosocial development in children.

Objective: We aimed to investigate the natural course of CU and to identify relevant factors associated with a poor CU prognosis in Korean children.

Methods: We retrospectively analyzed 253 children with episodes of wheals or angioedema at least 3 times a week that persisted for at least 6 weeks. Read More

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Epidemiology of urticaria including physical urticaria and angioedema in Korea.

Korean J Intern Med 2019 Mar 11;34(2):418-425. Epub 2018 May 11.

Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea.

Background/aims: Despite the high burden and frequency of urticaria, its epidemiology is not well known. We investigated the epidemiology of various type of urticaria in Korea and changes in its annual prevalence over 5 years.

Methods: We used data from the 2010 to 2014 Health Insurance Review and Assessment database, which covers the claims of 97. Read More

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Chronic inducible urticaria: A systematic review of treatment options.

J Allergy Clin Immunol 2018 05 10;141(5):1726-1734. Epub 2018 Feb 10.

Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address:

Background: Chronic inducible urticaria (CindU) is a condition characterized by the appearance of recurrent wheals, angioedema, or both as a response to specific and reproducible triggers.

Objective: We sought to systematically assess evidence on the efficacy and safety of treatment options for CindU. Results were used to inform the 2017 update of "The EAACI/GALEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Read More

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Chronic inducible urticarias in children.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1391-1393. Epub 2018 Feb 14.

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.

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November 2019