178 results match your criteria Urticaria Dermographism
Asian Pac J Allergy Immunol 2018 Jun 11. Epub 2018 Jun 11.
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Background: Chronic urticaria (CU) has an adverse effect on academic achievement and psychosocial development in children.
Objective: We aimed to investigate the natural course of CU and to identify relevant factors associated with a poor CU prognosis in Korean children.
Methods: We retrospectively analyzed 253 children with episodes of wheals or angioedema at least 3 times a week that persisted for at least 6 weeks. Read More
Korean J Intern Med 2018 May 11. Epub 2018 May 11.
Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Background/aims: Despite the high burden and frequency of urticaria, its epidemiology is not well known. We investigated the epidemiology of various type of urticaria in Korea and changes in its annual prevalence over 5 years.
Methods: We used data from the 2010 to 2014 Health Insurance Review and Assessment database, which covers the claims of 97. Read More
J Allergy Clin Immunol 2018 May 10;141(5):1726-1734. Epub 2018 Feb 10.
Department of Dermatology, Venerology and Allergy, Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address:
Background: Chronic inducible urticaria (CindU) is a condition characterized by the appearance of recurrent wheals, angioedema, or both as a response to specific and reproducible triggers.
Objective: We sought to systematically assess evidence on the efficacy and safety of treatment options for CindU. Results were used to inform the 2017 update of "The EAACI/GALEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria. Read More
World Allergy Organ J 2018 3;11(1). Epub 2018 Jan 3.
Universidad Espíritu Santo, Km. 2.5 vía La Puntilla, Código postal: 0901-952 Samborondón, Ecuador.
Background: The purpose of this study was to identify chronic urticaria (CU) etiologies and treatment modalities in Ecuador. We propose that the sample distribution fits the expected one, and that there is an association between the etiology and its treatment.
Methods: We performed a retrospective study involving 112 patients diagnosed with CU using a Checklist for a complete chronic urticaria medical history. Read More
Clin Exp Dermatol 2018 Apr 22;43(3):268-273. Epub 2017 Dec 22.
Department of Medicine, Surgery and Odontology Scuola Medica Salernitana, University of Salerno, Salerno, Italy.
Background: Dermographism is a condition characterized by a weal response to a combination of pressure and traction on skin surface, and its diagnosis is based on medical history, clinical criteria and provocation test. The Dermographic Tester , a pen-sized tool containing a spring-loaded blunt tip, is the most widely used instrument for the provocation test, and it exerts increasing pressures on the skin surface according to an arbitrary units (AU) scale. Analysing the mechanism of function and trying to convert the AUs to SI units (g/mm ), we found that this instrument had some defects and limits that would compromise a true and repeatable quantification of the weal response threshold. Read More
Postepy Dermatol Alergol 2017 Aug 2;34(4):346-349. Epub 2017 Aug 2.
Division of Allergy, Department of Chest Medicine, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey.
Introduction: Symptomatic dermographism (SD) is the most common form of physical urticaria. However, the role of neuroimmune mechanisms in SD is unclear.
Aim: To investigate circulating levels of brain-derived neurotrophic factor (BDNF) in symptomatic dermographism. Read More
J Allergy Clin Immunol 2018 Feb 24;141(2):638-649. Epub 2017 Jul 24.
Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Background: Omalizumab, a recombinant anti-IgE antibody, effectively treats chronic spontaneous urticaria. Evidence is lacking in patients with chronic inducible urticarias (CIndUs), which are frequently H-antihistamine resistant.
Objective: From the current published literature, we aimed to determine the strength of evidence for omalizumab efficacy and safety in the treatment of CIndUs. Read More
Curr Allergy Asthma Rep 2017 Aug;17(8):51
Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Caracas, Venezuela.
Purpose Of Review: This review aims to update the information available on the prevalence, clinical picture, diagnostic methods, and treatment of urticarias induced by external physical stimuli.
Recent Findings: Physical urticarias are present in up to 5% of the general population, and in 10 to 50% of patients with chronic urticaria. Recent investigations have provided evidence that the presence of physical urticaria alone or when comorbid with chronic spontaneous urticaria is associated with a worse prognosis and duration. Read More
Allergy Asthma Proc 2016 Nov;37(6):450-457
Pediatric Allergy and Immunology, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.
Background: Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for 6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU).
Objectives: To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification. Read More
J Allergy Clin Immunol Pract 2017 Mar - Apr;5(2):464-470. Epub 2016 Nov 9.
Group of Experimental and Clinical Allergy, IPS Universitaria, University of Antioquia, Medellín, Colombia.
Background: Information on the prevalence of inducible urticaria (IU) in patients with chronic spontaneous urticaria (CSU) and the factors affecting this prevalence is scarce in the literature.
Objectives: To estimate the frequency of IU in patients with CSU and to explore possible factors associated with CSU.
Methods: Patients older than 12 years diagnosed with CSU and a control group with no history of urticaria were recruited from 2 different cities. Read More
Biomedica 2016 Mar 3;36(1):10-21. Epub 2016 Mar 3.
Grupo de Alergología Clínica y Experimental (GACE), IPS Universitaria, Universidad de Antioquia, Medellín, Colombia.
Inducible urticaria is a heterogeneous group of skin disorders characterized by the appearance of wheals, pruritus and/or angioedema, sometimes accompanied by systemic symptoms caused by innocuous stimuli (cold, heat, pressure, etc.). This group of disorders compromises people's quality of life and most of the literature in this regard comes from case reports and case series since its epidemiology has been poorly studied and some cases are very rare. Read More
J Eur Acad Dermatol Venereol 2017 Mar 5;31(3):463-468. Epub 2016 Sep 5.
Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing, China.
Background: The underlying causes and factors contributing to the disease severity of chronic spontaneous urticaria (CSU) are unknown.
Objective: Given the important role of basophils in the pathogenesis of urticaria and that CD63 serves as a useful marker for basophil activation and detecting, CD63 expression of basophils is a reliable tool for diagnosing allergy and hypersensitivity reactions to different allergens; the objective of this study was to investigate whether the level of basophil CD63 expression is correlated with allergen sensitization, serum autoreactivity and basophil reactivity in patients with CSU.
Methods: Basophil-enriched leucocytes were separated from the blood of 64 patients with chronic urticaria (54 CSU patients and 10 symptomatic dermographism patients), 18 healthy control subjects and seven atopic donors without urticaria. Read More
A A Case Rep 2016 Jul;7(2):41-3
From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California.
A 54-year-old man with dermographism presented for spine surgery, and shortly after induction of anesthesia, he experienced severe hypotension and urticaria, resulting in cancellation of the case on suspicion of allergic reaction. For subsequent ventral hernia repair, a perioperative management strategy was devised, which resulted in an uneventful perioperative course. This case report is the first to demonstrate severe intraoperative hypotension and urticaria from dermographism. Read More
Am J Case Rep 2016 Jun 21;17:421-4. Epub 2016 Jun 21.
Department of Oral Diagnostic Science, King Abdulaziz University, Faculty of Dentistry, Jeddah, Saudi Arabia.
Background: Dermographism is a type of physical urticaria that can be induced by writing on the skin. It occurs in 2-5% of the population and is considered to be a normal physiological phenomenon. However, in a small subset of patients, it can be symptomatic and may affect the quality of life. Read More
Isr Med Assoc J 2016 Jan;18(1):65
J Eur Acad Dermatol Venereol 2016 Jan 1;30(1):41-9. Epub 2015 Oct 1.
Department of Dermatology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Background: Treatment guidelines for chronic spontaneous/idiopathic urticaria (CSU) are available; however, only 50% of patients are well controlled with approved doses of H1-antihistamines, and certain patients remain symptomatic despite receiving up to 4× the approved dose of H1-antihistamines plus H2 antihistamines and/or leucotriene-receptor antagonists.
Objectives: To highlight real-life clinical practice in Taiwan and to understand the unmet medical needs of CSU patients.
Methods: A nationwide cross-sectional, observational survey of 50 dermatologists and 200 CSU patients was conducted between June 2013 and November 2013. Read More
Clin Exp Dermatol 2015 Jun 18;40(4):399-403. Epub 2014 Dec 18.
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Background: Symptomatic dermographism is a common urticarial condition, which requires determination of provocation thresholds to confirm diagnosis and allow physicians to individualize management and therapy for optimal control of symptoms. To determine provocation thresholds, we have developed a provocation test device, the FricTest(®) 4.0. Read More
J Eur Acad Dermatol Venereol 2015 Apr 29;29(4):708-12. Epub 2014 Aug 29.
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin, Berlin, Germany.
Background: Symptomatic dermographism is the most common form of physical urticaria with a prevalence of 2-5%. However, its clinical picture has rarely been described.
Objective: To understand more of patients' views about the practical aspects of their condition, its cause and impact on quality of life. Read More
Contact Dermatitis 2014 Jul;71(1):62-4
St John's Institute of Dermatology, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.
Dermatitis 2014 Mar-Apr;25(2):101-3
From the *Leicester Royal Infirmary, Leicester; and †Leeds General Infirmary, United Kingdom.
JAMA Dermatol 2014 Mar;150(3):288-90
Department of Dermatology, Venerology, and Allergology, Allergie-Centrum-Charité, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Importance: Omalizumab has emerged as a novel and effective treatment option for patients with antihistamine-resistant chronic urticaria. It is unclear whether patients with recurrent urticaria symptoms after discontinuation of omalizumab treatment can benefit from retreatment.
Objective: To assess the response of patients with chronic urticaria who receive omalizumab retreatment. Read More
Immunol Allergy Clin North Am 2014 Feb 28;34(1):73-88. Epub 2013 Oct 28.
Department of Dermatology and Allergy, Allergie - Centrum Charité/ECARF, Charité - Universitätsmedizin Berlin, Charitéplatz 1, Berlin 10117, Germany.
Physical urticarias are a unique subgroup of chronic urticaria in which urticarial responses can be reproducibly induced by different specific physical stimuli acting on the skin. These conditions include urticaria factitia/symptomatic dermographism, delayed pressure urticaria, cold contact urticaria, heat contact urticaria, solar urticaria, and vibratory urticaria/angioedema. Physical urticarias and cholinergic urticarias are diagnosed based on the patients' history and provocation tests including trigger threshold testing where possible. Read More
Br J Dermatol 2013 Dec;169(6):1362-3
Department of Neurology, University of California, 500 Parnassus Ave, Box 0114, San Francisco, CA, 94143-0114, U.S.A.
Int J Dermatol 2013 Nov 8;52(11):1387-91. Epub 2013 Jul 8.
Leumit Health Services, Barzilai Medical Center, Ben Gurion University of Negev, Ashkelon, Israel; Medicine B Department, Barzilai Medical Center, Ben Gurion University of Negev, Ashkelon, Israel; Allergy and Clinical Immunology Unit, Barzilai Medical Center, Ben Gurion University of Negev, Ashkelon, Israel.
Background: There are few data regarding epidemiology and clinical features of urticarial diseases in the elderly population.
Objective: The aim of the study was to determine the clinical and laboratory characteristics of chronic idiopathic urticaria (CIU) in the geriatric population.
Methods: Electronic medical records of outpatient allergy consultations due to a diagnosis of CIU were retrospectively reviewed to collect demographic data, urticaria activity score, results of autologous serum skin test (ASST), and laboratory workup. Read More
Indian J Dermatol 2013 May;58(3):211-8
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité Universitätsmedizin Berlin, Berlin, Germany.
Acute urticaria do not need extensive diagnostic procedures. Urticaria activity score is a useful tool for evaluation of urticaria. Complete blood count, Erythrocyte sedimentation rate and C reactive protein are important investigations for diagnosis of infections in urticaria. Read More
BMJ Case Rep 2013 May 22;2013. Epub 2013 May 22.
Department of Medicine, Medical College Kolkata, Kolkata, West Bengal, India.
A middle aged female patient presented with generalised palpable purpura associated with intense pruritus along with subconjunctival haemorrhage and orbital inflammation. There was extensive dermographism. Other systemic examinations were within normal limits. Read More
Clin Exp Dermatol 2013 Jun;38(4):360-6; quiz 366
Department of Dermatology and Allergology, Allergie-Centrum-Charité, Charit\xE9-Universitätsmedizin Berlin, Berlin, Germany.
Background: Symptomatic dermographism is a common urticarial condition. There is a need for an objective method to determine the provocation threshold for patients, in order to facilitate individualized diagnosis and treatment.
Aim: To compare the dermal responses evoked by a new type of dermographometer (FricTest) with those evoked by a spring-loaded dermographometer (the Dermographic tester). Read More
Arch Dis Child 2013 Aug 20;98(8):607. Epub 2013 Apr 20.
Dermatology, Department of Specialised, Experimental and Diagnostic Medicine, Università di Bologna, Bologna, Italy.
Ann Dermatol Venereol 2012 Oct 29;139(10):636-40. Epub 2012 Jun 29.
Service de dermatologie, hôpital Saint-Louis, Assistance publique-Hôpitaux de Paris, 1, avenue Claude-Vellefaux, 75010 Paris, France.
Background: Hypereosinophilic syndrome (HES) is defined as an eosinophil count equal to or greater than 1.5 G/L for more than 6 months with organ damage (heart, nervous system, lung, etc) after the exclusion of other common causes of eosinophilia. A myeloproliferative variant of HES with FIP1L1-PDGFRα fusion gene inducing constitutive activation of a tyrosine kinase receptor has been characterized. Read More
Allergol Immunopathol (Madr) 2013 May-Jun;41(3):163-8. Epub 2012 Sep 30.
Hacettepe University, School of Medicine, Department of Chest Diseases, Adult Allergy Unit, Ankara, Turkey.
Background: Drug provocation testing should be performed before safely prescribing an analgesic for patients that are hypersensitive to non-steroidal anti-inflammatory drugs (NSAIDs). Whether or not the direct histamine releasing effect of codeine renders it useful in NSAID-hypersensitive patients is unknown. This study aimed to determine if codeine could be recommended as a safe treatment option for NSAID-hypersensitive patients without the need for oral drug provocation testing. Read More
Allergy Asthma Proc 2012 Sep-Oct;33(5):421-6
Allergology and Immunology Unit, Novara Hospital-Experimental Program Piemonte Allergy Network, Novara, Italy.
The provocation test (PT) with the suspected drug represents the gold standard in the diagnosis of non-IgE hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs). Nevertheless, there is no consensus regarding the clinical management of suspected NSAID-sensitive patients. This study assessed if a PT with the suspected drug is a reliable and safe proceeding to confirm NSAID hypersensitivity in patients with a clinical history of urticaria/angioedema (Urt/AE). Read More
Allergol Immunopathol (Madr) 2013 Jan-Feb;41(1):65-6. Epub 2012 Jan 21.
Hacettepe University, Faculty of Medicine, Department of Pediatric Allergy and Asthma, 06100 Sihhiye, Ankara, Turkey. Electronic address:
Rheumatol Int 2012 Aug 23;32(8):2551-5. Epub 2011 Jul 23.
Department of Dermatology, Hospital das Clínicas, Sao Paulo University, Sao Paulo, Brazil.
Adult-onset Still's disease (AOSD) patients typically present with arthralgia, fever, lymphadenopathy and a transient salmon maculopapular rash. Only approximately 25 cases of AOSD with urticaria were described in the literature. In this article, the authors report three additional cases of AOSD with urticarial and dermographic lesions who had a good clinical response to glucocorticoid and antihistamines. Read More
J Biomed Res 2011 Mar;25(2):141-7
Department of Dermatology, Haidian Hospital, Beijing 10080, China ; Section of Clinical Immunology, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, Jiangsu, China.
This present study was aimed to investigate the roles of the receptors of Th1/Th2 cytokines and chemokines in the pathogenesis of chronic idiopathic urticaria (CIU). Thirty patients with CIU, 30 patients with dermographism and 30 healthy controls were randomly enrolled. Reverse transcription-PCR (RT-PCR) was used to analyze the mRNA of cytokine receptors in peripheral blood mononuclear cells (PBMCs). Read More
J Eur Acad Dermatol Venereol 2011 Oct 22;25(10):1194-9. Epub 2010 Dec 22.
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Background: Physical urticarias (PU) are an urticarial response to different specific physical stimuli. PU can occur concurrently with chronic spontaneous urticaria or another type of PU.
Objective: We aimed to study the prevalence, type, clinical data and natural course of each type of PU and other inducible urticarias and also the prognostic factors for remission of patients visiting a tertiary referral hospital. Read More
Int Arch Allergy Immunol 2011 24;154(2):177-80. Epub 2010 Aug 24.
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.
In physical urticaria, exogenous physical factors such as thermal triggers, solar radiation and mechanic triggers including friction or pressure are responsible for the elicitation of symptoms in the skin of patients. Avoidance of the respective stimulus is usually difficult or impossible, and many patients are not sufficiently treated with standard antihistamines. We report that treatment with omalizumab (Xolair®) of 7 patients with physical urticarias [solar urticaria (n = 2), urticaria factitia/symptomatic dermographism (n = 2), cold urticaria, delayed pressure urticaria and localized heat urticaria] resulted in complete symptom control within days after the first injection in 5 patients. Read More
J Plast Reconstr Aesthet Surg 2011 Jan 19;64(1):141. Epub 2010 Jun 19.
Ann Dermatol Venereol 2010 Jun-Jul;137(6-7):444-50. Epub 2010 Jun 9.
Service de dermatologie, centre hospitalier universitaire, université François-Rabelais, 2, boulevard Tonnellé, 37044 Tours cedex 09, France.
Background: Chronic urticaria (CU) is a debilitating disease, and patients and their physicians often seek an aetiological explanation. Studies have suggested that idiopathic CU is associated with the presence of serum auto-antibodies that may be detected by autologous serum skin test (ASST).
Aim: To confirm the frequency of positivity of ASST and to evaluate its usefulness and possible correlation with the severity of urticaria (greater resistance to AH1, greater activity score or longer duration). Read More
Acta Clin Croat 2009 Mar;48(1):59-64
University Department of Dermatology and Venereology, Sestre milosrdnice University Hospital, Zagreb, Croatia.
The term mastocytosis is referred to as an array of uncommon, usually sporadic, heterogeneous clinical illnesses that result from the hyperplasia of tissue mast cells. It comprises many different clinical manifestations varying from indolent cutaneous forms to systemic and malignant conditions. The characteristic presentation of mastocytosis consists of cutaneous manifestations: either a solitary mastocytoma, urticaria pigmentosa, or less commonly, diffuse cutaneous mastocytosis. Read More
Int Arch Allergy Immunol 2009 4;150(3):299-306. Epub 2009 Jun 4.
Department of Chest Diseases, Adult Allergy Unit, Hacettepe University School of Medicine, Ankara, Turkey.
Background: The coexistence of allergic diseases and chronic urticaria (CU) is not uncommon. Our aim was to show the prevalence of allergic diseases in chronic urticaria patients and whether possible risk factors precipitate the development of these conditions.
Methods: The data of 953 patients diagnosed with CU in our adult allergy clinic between January 1991 and June 2006 were retrospectively evaluated. Read More
Medicine (Baltimore) 2009 Jan;88(1):23-31
The Université Louis Pasteur, Hôpitaux Universitaires, Strasbourg, France.
We conducted the current study to define within the spectrum of the neutrophilic dermatoses a group of patients with an urticarial rash clinically and a neutrophilic dermatosis histopathologically. We reviewed the literature on neutrophilic urticaria and we report here a series of patients with this unique presentation. We reviewed all cutaneous biopsies submitted to our department between 2000 and 2006 in which histopathologic evaluation was compatible with this entity. Read More
J Am Acad Dermatol 2008 Nov 5;59(5):752-7. Epub 2008 Sep 5.
Dermatology Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom.
Background: Symptomatic dermographism is the most common type of physical urticaria. It can be severe and poorly controlled with H1 antihistamines in some patients. Photochemotherapy (psoralen plus ultraviolet [UV] A) may help the itch of dermographism but the effect of narrowband (NB) UVB therapy has not been previously studied. Read More
Indian J Dermatol Venereol Leprol 2008 May-Jun;74(3):271-2
Postgrad Med J 2008 Jan;84(987):e1-2
University of Florence, Department of Dermatological Sciences, Via della Pergola 58/60, 50121 Florence, Italy.
Physical urticarias are a group of mucocutaneous disorders characterised by the appearance of whealing and/or angioedema and induced by physical stimuli. A 24-year-old Caucasian male affected by ultraviolet A-induced solar urticaria, specific food-dependent exercise-induced anaphylaxis, symptomatic dermographism and allergic rhinoconjunctivitis is described. Read More
J Asthma Allergy 2008 Dec 9;2:9-16. Epub 2008 Dec 9.
Dipartimento di Medicina clinica e delle Patologie Emergenti;
In vitro and in vivo clinical and experimental data have suggested that leukotrienes play a key role in inflammatory reactions of the skin. Antileukotriene drugs, ie, leukotriene receptor antagonists and synthesis inhibitors, are a class of anti-inflammatory drugs that have shown clinical efficacy in the management of asthma and in rhinitis with asthma. We searched MEDLINE database and carried out a manual search on journals specializing in allergy and dermatology for the use of antileukotriene drugs in urticaria. Read More
Acta Derm Venereol 2007 ;87(6):493-8
Department of Clinical Sciences, University Hospital, SE-221 85 Lund, Sweden.
Studies report that urticarial dermographism is exacerbated by "life events" and emotions. The aim of this study was to determine what aspects of life quality are affected by symptomatic dermographism and whether acute stress is a potential triggering factor. A total of 21 adult patients with urticarial dermographism completed a questionnaire on symptoms and quality of life. Read More
Pediatr Dermatol 2007 Jul-Aug;24(4):391-3
Department of Pediatrics, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
A 10-month-old girl with marked symptomatic dermographism presented with linear bands at the sock line noted to have developed following an episode of localized urticaria and angioedema at the sock line. We speculate that release of mast cell mediators associated with the dermographism may have triggered the development of the linear bands. Read More
Ann Dermatol Venereol 2007 Mar;134(3 Pt 1):275-6
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Jun 27;103(6):774-9. Epub 2007 Feb 27.
Glasgow Dental Hospital and School, Glasgow, Scotland.
There are few papers in the literature that describe pressure urticaria in the maxillofacial region. We present 2 cases and discuss the significance and principles of management. One case describes the diagnosis of pressure urticaria and the second describes the dental management of a patient with severe pressure urticaria. Read More