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Radiol Case Rep 2022 Jul 9;17(7):2464-2469. Epub 2022 May 9.

Department of Radiology, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Jl. Pasteur No. 38, Pasteur, Kec. Sukajadi, Bandung, Indonesia.

We describe a case of a 2-year-old girl with congenital megaureter presenting as intraabdominal cystic masses. The patient presented with a lump in abdomen that has been getting bigger since birth accompanied by pain. Ultrasonography that was taken when the patient was 2 years old showed a cystic mass with thick septation and pelvocaliectasis of the left kidney. Read More

Clin J Am Soc Nephrol 2022 May 18. Epub 2022 May 18.

Division of Nephrology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, and Department of Anatomy, Cell Biology and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana

AKI is a syndrome, not a disease. It results from many different primary and/or secondary etiologies and is often multifactorial, especially in the hospitalized patient. This review discusses the pathophysiology of three etiologies that cause AKI, those being kidney hypoperfusion, abdominal compartment syndrome, and urinary tract obstruction. Read More

Clin Case Rep 2022 May 9;10(5):e05820. Epub 2022 May 9.

University Hospitals of Leicester NHS Foundation Trust Glenfield Hospital Leicester UK.

Spontaneous or non-traumatic rupture of the renal tract is an infrequent presentation, and it is most frequently caused by ureteric obstruction. Rupture could occur at any level of the upper urinary tract. However, it is most common at the renal calyces and complications that could arise include; urinoma, and or hematoma collection which could progress to abscess formation and sepsis. Read More

Urol Case Rep 2022 Jul 2;43:102098. Epub 2022 May 2.

Urology Department FSI Hospital, Tunis, Tunisia.

Spontaneous rupture of the upper urinary tract is a rare and potentially serious pathology. Lithiasis is the most frequent cause. However, other causes are incriminated such as trauma, retroperitoneal fibrosis and especially stenosing tumors. Read More

Biomed Res Int 2022 6;2022:5780964. Epub 2022 May 6.

Department of Herbology, College of Korean Medicine, Daegu Haany University, 136, Sinchendong-ro, Suseong-gu, Daegu 42158, Republic of Korea.

Renal fibrosis is a type of chronic kidney disease (CKD) induced by infiltration of inflammatory cells, myofibroblast accumulation, and ECM production in the kidney. From a long time ago, Corni Fructus (CF) is known to supplement the liver and kidney with its tepid properties. In this study, we investigated the renal protective mechanism of CF, which is known to supplement the kidney, in rat model of unilateral ureteral obstruction (UUO). Read More

J Clin Med 2022 Apr 22;11(9). Epub 2022 Apr 22.

Department of Obstetrics and Prenatal Medicine, University Hospital Bonn, Venusberg Campus 1, 53127 Bonn, Germany.

(1) Background: The aim of this study was to compare perinatal outcomes and complication rates of vesicoamniotic shunting (VAS) before 17 + 0 weeks in isolated LUTO (lower urinary tract obstruction) with the Somatex intrauterine shunt vs. the Harrison fetal bladder shunt. (2) Methods: This is a retrospective cohort study in two tertiary fetal medicine centers. Read More

Transl Androl Urol 2022 Apr;11(4):480-494

Department of Intervention, Meizhou People's Hospital, Meizhou Academy of Medical Sciences, Meizhou, China.

Background: Prostatic arterial embolization (PAE) is an effective minimally invasive treatment for lower urinary tract obstruction and hematuria in patients with benign prostatic hyperplasia (BPH). This study was aim to evaluate the safety and short-term efficacy of drug epirubicin-loaded beads transarterial prostatic arterial chemoembolization (DEB-PACE) for the treatment of advanced prostate cancer (PC) with lower urinary tract obstruction or hematuria.

Methods: A total of 8 patients with advanced PC undergoing DEB-PACE from August 2020 to February 2022 were retrospectively enrolled. Read More

BMJ Case Rep 2022 May 11;15(5). Epub 2022 May 11.

Pediatric Surgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Renal parapelvic cysts (RPC) have an incidence of approximately 1%-3% in the general population. However, they rarely present in children with only two cases reported in literature. RPC are often misdiagnosed as it is difficult to distinguish them from hydronephrosis on preoperative imaging. Read More

J Nephrol 2022 May 11. Epub 2022 May 11.

Pediatric Urology, Adana City Research and Education Hospital, Adana, Turkey.

Urol Case Rep 2022 May 1;42:102037. Epub 2022 Mar 1.

Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.

In contemporary urological practice periurethral abscesses are rare. We report the case of a 61-year-old presenting with a painless penile mass and urinary retention. He underwent imaging with ultrasonography, targeted antibiotics and successful source control through open incision and drainage. Read More

Eur Urol Open Sci 2022 May 7;39:72-78. Epub 2022 Apr 7.

Department of Urology, Basingstoke and North Hampshire Hospital, Basingstoke, UK.

Background: Rezūm water vapour ablation is an effective minimally invasive surgical therapy for the treatment of bladder outflow obstruction.

Objective: To present early outcomes and reoperation rates after Rezūm, including an analysis of retreatment rates to gain an insight into optimal patient selection and the durability of the procedure.

Design Setting And Participants: Data were prospectively collected for consecutive patients undergoing Rezūm for symptomatic benign prostatic hyperplasia between March 2017 and January 2020 at two hospital sites. Read More

J Avian Med Surg 2022 May;36(1):70-77

Division of Diagnostic Imaging, Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CM Utrecht, The Netherlands.

A 2-year-old domestic hen was presented for a 15-day history of intermittent left leg lameness. The owners also observed a decrease in egg quality during that period. Physical examination of the bird revealed a generalized weakness with a flattened pale comb. Read More

Asian J Surg 2022 May 4. Epub 2022 May 4.

Department of Urology, Urology Research Institute, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China; Fujian Key Laboratory of Precision Medicine for Cancer, The First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China. Electronic address:

Objective: This study was to explore the risk factors for postoperative bladder neck contracture (BNC) after transurethral operation of prostate in patients with small-volume prostatic obstruction.

Methods: Clinicopathologic data at our center from February 2016 to January 2020 were retrospectively collected and analyzed. Clinicopathological characteristics between patients with and without BNC were compared. Read More

FASEB J 2022 Jun;36(6):e22342

Key Laboratory of Kidney Disease Prevention and Control Technology, Kidney Disease Center, Institute of Nephrology, the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China.

Renal fibrosis is the final common outcome of chronic kidney disease (CKD), which remains a huge challenge due to a lack of targeted treatment. Growing evidence suggests that during the process of CKD, the integrity and function of mitochondria in renal tubular epithelial cells (TECs) are generally impaired and strongly connected with the progression of renal fibrosis. Mitophagy, a selective form of autophagy, could remove aberrant mitochondria to maintain mitochondrial homeostasis. Read More

Front Pharmacol 2022 19;13:858676. Epub 2022 Apr 19.

Clinical Systems Biology Laboratories, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Acute kidney injury (AKI), a common and serious clinical kidney syndrome with high incidence and mortality, is caused by multiple pathogenic factors, such as ischemia, nephrotoxic drugs, oxidative stress, inflammation, and urinary tract obstruction. Cell death, which is divided into several types, is critical for normal growth and development and maintaining dynamic balance. Ferroptosis, an iron-dependent nonapoptotic type of cell death, is characterized by iron overload, reactive oxygen species accumulation, and lipid peroxidation. Read More

Asian J Urol 2022 Apr 29;9(2):109-118. Epub 2021 May 29.

Department of Moalajat, Regional Research Institute of Unani Medicine, Naseem Bagh, University of Kashmir, Srinagar, Jammu and Kashmir, India.

Objective: Conventional treatments for benign prostatic hyperplasia (BPH) like 5alpha-reductase inhibitors and invasive surgery are associated with some obvious side effects. Conversely, evidence, though limited, has shown that alternative medicines are safer and have potential to improve the lower urinary tract symptoms (LUTS) and quality of life in addition to improving sexual dysfunction in patients with BPH. The current article aimed to include an overview of BPH, different ways of its management, and particularly its appreciation in Greco-Arab (Unani) system of medicine, one of the alternative medicinal systems. Read More

Andes Pediatr 2022 Feb 28;93(1):78-85. Epub 2022 Mar 28.

Facultad de Medicina, Universidad de Chile, Santiago, Chile.

The presence of fetal megacystis in a renal ultrasound may suggest a mechanical or functional bladder outlet obstruction, an uncommon condition with a poor outcome.

Objective: To determine prog nostic factors in fetuses with prenatal diagnosis of megacystis.

Patients And Method: Retrospective study carried out between 2003 and 2018 in the Orient Perinatal Reference Center (CERPO), Uni versity of Chile. Read More

Can Vet J 2022 05;63(5):504-509

VCA Canada, Calgary Animal Referral & Emergency Centre, 7140 12 Street SE, Calgary, Alberta T2H 2Y4; VCA Canada, Western Veterinary Specialists & Emergency Centre - Surgery, 1802 10 Avenue SW, Calgary, Alberta T3C 0J8.

A 4-month-old, 7 kg, intact male, Bernese mountain dog was presented for obstructive struvite ureterolithiasis. Multiple urethroliths, ureteroliths, and urocystoliths were present. Based on an abdominal ultrasound, there was severe left hydronephrosis and hydroureter from distal ureterolith obstruction, just proximal to the vesicoureteral junction. Read More

Res Rep Urol 2022 23;14:159-166. Epub 2022 Apr 23.

Department of Earth and Planetary Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.

Introduction: Ureteral stents are effective in alleviating flow disruptions in the urinary tract, whether due to ureteral stones, strictures or extrinsic ureteral obstruction. However, significant stent encrustation on the external and/or internal stent lumen walls can occur, which may interfere with stent functioning and/or removal. Currently, there is only limited, generally qualitative, information on the distribution, mineral structure, and chemical content of these deposits, particularly in terms of stent lumen encrustation. Read More

J Ethnopharmacol 2022 Apr 28:115314. Epub 2022 Apr 28.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia. Electronic address:

Ethnopharmacological Relevance: Citrullus lanatus (Thunb.) belongs to the ground family, Cucurbitaceae, known for edible fruit. Besides nutritional benefits, the traditional herbal practitioners in Pakistan and India used their seeds to treat gastrointestinal, respiratory, and urinary disorders. Read More

BMJ Open 2022 Apr 29;12(4):e056234. Epub 2022 Apr 29.

Human Movement Sciences, Faculty of Behavioural and Movement Sciences, Amsterdam Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objectives: To systematically review the literature regarding the reliability and validity of assessment methods available in primary care for bladder outlet obstruction or benign prostatic obstruction in men with lower urinary tract symptoms (LUTS).

Design: Systematic review with best evidence synthesis.

Setting: Primary care. Read More

J Comp Pathol 2022 May 31;193:20-24. Epub 2022 Mar 31.

Laboratory of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Japan. Electronic address:

We investigated the pathological characteristics of renal dysplasia with hydronephrosis and congenital ureteral stricture in two calves. Macroscopically, the affected kidneys were enlarged and the renal calyces were dilated and associated with ureteral strictures. Histopathologically, multifocal regions of mesenchyme were observed in the renal medulla. Read More

Urologiia 2022 May(2):5-10

Rostov State Medical University of the Russian Federation Ministry of Public Health, Rostov-on-Don, Russia.

Introduction: Congenital ureterovesical junction (UVJ) obstructions quite rarely serve as an indication for ureteral reimplantation, and recurrent obstructions resulting from surgical treatment are even less frequent. Cases of acquired UVJ obstruction following endoscopy and ureteral reimplantation done for vesicoureteral reflux correction are fairly rare. The lack of known publications analyzing treatment of recurrent obstructive megaureter predetermines topicality of our research. Read More

Cir Pediatr 2022 Apr 1;35(2):85-90. Epub 2022 Apr 1.

Donostia University Hospital. San Sebastian (Spain).

Objective: Traditionally, double J stent removal in pediatric patients has required cystoscopy under general anesthesia. Magnetic stents allow for double J stent removal without the need for anesthesia. This work describes our initial experience with these stents. Read More

Eur Urol Focus 2022 Apr 25. Epub 2022 Apr 25.

Department of Urology, School of Medicine, University of St. Gallen, St. Gallen, Switzerland.

Prostatic artery embolisation (PAE) is now endorsed by international evidence-based guidelines as a treatment for lower urinary tract symptoms presumed secondary to benign prostatic obstruction (LUTS/BPO) for selected patients. PAE is a truly minimally invasive technique, with proven efficacy and safety demonstrated for the short- to mid-term. As it has a unique treatment approach (endovascular instead of transurethral), its profile and ideal application differ clearly from other treatments for LUTS/BPO, which must be considered for patient selection. Read More

BJU Int 2022 Apr 28. Epub 2022 Apr 28.

Department of Urology, Aberdeen Royal Infirmary - NHS Grampian, Aberdeen, UK.

Objective: To identify whether men aged ≥40 years with bladder stones (BS) benefit from treatment of benign prostatic obstruction (BPO).

Patients And Methods: A regional, retrospective study of patients undergoing BS surgery between January 2011 and December 2018 was performed using a prospectively collected database. The primary outcome was BS recurrence after successful removal. Read More

BJUI Compass 2021 Sep 6;2(5):331-337. Epub 2021 Apr 6.

Department of Urology University Medical Centre Utrecht Utrecht The Netherlands.

Objectives: To present the short-term and long-term outcomes of the psoas hitch procedure in a large cohort with long-term follow-up.

Patients And Methods: A multicenter, retrospective cohort study was conducted. Patients were included if they had undergone an open psoas hitch procedure with ureteral reimplantation for different types of distal ureteral pathology between 1993 and 2017. Read More

BMC Urol 2022 Apr 24;22(1):69. Epub 2022 Apr 24.

Department of Urology, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital Bandung, Jln. Pasteur No. 38, Bandung, Indonesia.

Introduction: Bladder outlet obstruction (BOO) was caused by a series of histological and biochemical changes in the bladder wall, through the inflammation process in the bladder wall, hypertrophy and fibrosis. ADSC has an important role in bladder regeneration.

Methods And Materials: This study was an experimental randomized study using male Wistar rats which were monitored at 2 and 4 weeks to determine the effect of ADSC therapy on TGF-β1 type I collagen, and degree of fibrosis. Read More

Biochem Biophys Res Commun 2022 Jun 15;610:154-161. Epub 2022 Apr 15.

Department of Nephrology, Qilu Hospital of Shandong University, Jinan, 250012, Shandong, China. Electronic address:

Renal fibrosis is the ultimate presentation of chronic kidney disease, which progresses to end-stage renal disease. Hydroxychloroquine (HCQ) has been adapted for the treatment of autoimmune diseases; however, the potential mechanism underlying the role of HCQ in renal fibrosis remains unclear. C57BL/6 J mice were randomly divided into three groups (sham group, UUO group, and UUO + HCQ group (20 mg/kg)). Read More