3,997 results match your criteria Urinary Tract Infections in Pregnancy


Pattern of Antibiotic Use in the Perinatal Period in a Public University Hospital in Romania.

Medicina (Kaunas) 2022 Jun 7;58(6). Epub 2022 Jun 7.

Psycho-Neurosciences and Recovery Department, Faculty of Medicine and Pharmacy, University of Oradea, 1 University Street, 410087 Oradea, Romania.

: Antibiotics are the most frequently prescribed drugs in hospitals and their prescription is increased during pregnancy and labor. There are limited data about this issue, and the safe use of antibiotics in pregnancy and antibiotic resistance remains a concern. The aim of the study is to evaluate the use of antibiotics among pregnant women attending hospital for five years. Read More

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Pyelonephritis complicated by a perirenal abscess in a pregnant woman: Exceptional cause of fetal death in utero.

Urol Case Rep 2022 Sep 9;44:102126. Epub 2022 Jun 9.

Urology Department FSI Hospital, Tunis, Tunisia.

Acute pyelonephritis is the most common bacterial infection during pregnancy. If not diagnosed and treated promptly, it can lead to serious maternal and fetal complications. In the literature, a few cases of perirenal abscess complicating acute pyelonephritis during pregnancy have been reported. Read More

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September 2022

Screening for low-tract genital infections in women with threatened preterm labour. Which role?

Gynecol Obstet Invest 2022 Jun 22. Epub 2022 Jun 22.

Objectives: to evaluate the possible relationship between cultural specimens and preterm birth in women admitted for threatened preterm labour. Preterm birth is the leading cause of neonatal mortality and antenatal hospitalization: several risk factors including intrauterine infections have been identified but its real causes remain poorly understood.

Design: retrospective, multicentre, cohort study including 250 women admitted for threatened preterm labour. Read More

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First trimester pregnancy exposure to fosfomycin and risk of major congenital anomaly: a comparative study in the EFEMERIS database.

Infection 2022 Jun 11. Epub 2022 Jun 11.

Réseau REGARDS, Laboratoire de Pharmacologie Médicale et Clinique, Toulouse University Hospital (CHU de Toulouse), 37 Allées Jules Guesde, 31000, Toulouse, France.

Purpose: Fosfomycin trometamol has been recommended as first-line bactericidal antibiotic for urinary tract infections in pregnant women since 2015 in France. However, studies assessing fosfomycin safety in pregnancy are sparse. This study aimed to assess the risk of major Congenital Anomaly (CA) after fosfomycin exposure during the first trimester of pregnancy. Read More

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Sustained effect of LACTIN-V (Lactobacillus crispatus CTV-05) on genital immunology following standard bacterial vaginosis treatment: results from a randomised, placebo-controlled trial.

Lancet Microbe 2022 Jun 21;3(6):e435-e442. Epub 2022 Apr 21.

Department of Medicine, University of Toronto, Toronto, ON, Canada; Department of Immunology, University of Toronto, Toronto, ON, Canada; Department of Medicine, University Health Network, Toronto, ON, Canada.

Background: Bacterial vaginosis might increase HIV risk by eliciting genital inflammation and epithelial barrier disruption, whereas vaginal Lactobacillus crispatus is associated with immune quiescence and HIV protection. We investigated the effect of a live biotherapeutic containing L crispatus CTV-05 (LACTIN-V) on genital immunology and key vaginal bacteria.

Methods: This substudy included women aged 18-45 years who participated in the randomised, placebo-controlled, phase 2b trial of LACTIN-V to reduce bacterial vaginosis recurrence, conducted at four universities and hospitals in the USA. Read More

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Risk factors associated with infections in pregnant women with systemic lupus erythematosus.

Rev Assoc Med Bras (1992) 2022 Apr;68(4):536-541

Universidade do Estado do Rio de Janeiro - Rio de Janeiro (RJ), Brazil.

Objective: The aim of this study was to analyze the occurrence and risk factors associated with infections during pregnancy in patients with systemic lupus erythematosus.

Methods: This is a retrospective cohort study using the data of pregnant women who were followed up between 2011 and 2018 at a university hospital.

Results: The data of 221 pregnant women with systemic lupus erythematosus were analyzed. Read More

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Role of Infection and Leukocytes in Male Infertility.

Adv Exp Med Biol 2022 ;1358:115-140

American Center for Reproductive Medicine, Cleveland Clinic, Cleveland, OH, USA.

Male infertility is considered as a multifactorial complex reproductive illness, and male urogenital infection and inflammation are crucial etiologies contributing up to 35% of all cases. Mostly triggered by sexually transmitted diseases and uropathogens, chronic manifestation of such infection may cause irreversible infertility in the male. Male urogenital infection involves bacterial, viral, protozoal, and fungal infections many of which remain asymptomatic most of the time and are passed to the sexual partner leading to fertilization failure, pregnancy loss, and even development of illness in the offspring. Read More

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ROLE OF PRE-CESAREAN SECTION CEFOTAXIME IN AMELIORATED POST-CESAREAN COMPLICATION.

Wiad Lek 2022 ;75(4 pt 1):818-823

UNIVERSITY OF KUFA, KUFA, IRAQ.

Objective: The aim: The purpose of this study was to examine the efficacy of cefotaxime before and after skin incision in avoiding post-operative infection complications in caesarean section women, also evaluation the efficacy of cefotaxime in reducing post-caesarean section complications.

Patients And Methods: Materials and methods: We conducted 150 women who undergoing caesarean section in the Obstetrics & Gynecological Department, Babylon government from January, 2021 to March, 2021. The caesarean operations were done by using standard protocols. Read More

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The efficacy of pivmecillinam in oral step-down treatment in hospitalised patients with E. coli bacteremic urinary tract infection; a single-arm, uncontrolled treatment study.

BMC Infect Dis 2022 May 19;22(1):478. Epub 2022 May 19.

Department of Infectious Diseases, Vestfold Hospital Trust, Postbox 2168, 3103, Tønsberg, Norway.

Background: The role of oral beta-lactam antibiotics in treating febrile urinary tract infections (UTI) is not yet definite. Today, fluoroquinolones together with trimethoprim-sulfamethoxazole (TMP-MTX) are considered standard of care and often the only available evidence-based oral treatment for febrile UTI. This study clarifies the efficacy and safety of pivmecillinam (PIV) used as step-down therapy for bacteremic urinary tract infection (UTI). Read More

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Demonstrating the utility of Escherichia coli asymptomatic bacteriuria isolates' virulence profile towards diagnosis and management-A preliminary analysis.

PLoS One 2022 6;17(5):e0267296. Epub 2022 May 6.

Medical Education Research and Development Unit (MERDU), Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Asymptomatic bacteriuria (ASB) caused by Escherichia coli (E. coli) is a significant condition associated with pregnancy and is considered as prognostic for the development of symptomatic urinary tract infection (UTI). However, treating all ASB increases the use of antibiotics and leads to the development of multidrug resistance (MDR). Read More

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[Modern algorithm of diagnosis and treatment of acute gestational pyelonephritis in a large industrial city].

Urologiia 2022 May(2):34-42

Perm State Medical University named after E.A. Wagner Academy of Health of the Russian Federation, Perm, Russia.

The Purpose Of The Study: to develop a modern algorithm for the diagnosis and treatment of acute gestational pyelonephritis in a large industrial city and to study the possibilities of phytotherapy as an integral part of this algorithm.

Materials And Methods: The study consisted of two stages and included 629 patients treated over 12 years (2010-2021) in Perm city with a population of 1.1 million people. Read More

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Case Report: Fatal Outcome for a Preterm Newborn With Meningitis Caused by Extended-Spectrum β-Lactamase-Producing Sequence Type 1193.

Front Pediatr 2022 6;10:866762. Epub 2022 Apr 6.

Department of Neonatology, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.

Introduction: In this case report, we describe an extended-spectrum beta-lactamase (ESBL) - strain of sequence type (ST) 1193, a novel, virulent, multidrug-resistant (MDR) clone with a rapid global spread. ST 1193 has been more commonly associated with invasive disease than other ESBL- STs. To our knowledge, this is the first known case in Sweden where a newborn died of an ESBL- ST 1193 meningitis. Read More

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Maternal Age and Stage of Pregnancy as Determinants of UTI in Pregnancy: A Case of Tamale, Ghana.

Infect Dis Obstet Gynecol 2022 12;2022:3616028. Epub 2022 Apr 12.

Department of Surgery, Tamale Teaching Hospital, P.O. Box TL 16, Tamale, Ghana.

Introduction: Urinary tract infection (UTI) is the world's second most common cause of death, trailing only respiratory tract infections. Because of anatomical and physiological changes along the urinary tract, pregnant women accounted for approximately 20% of all cases of urinary tract infection.

Aim: This study sought to assess maternal age and stage of pregnancy as determinants of UTI among pregnant women in Tamale. Read More

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A Study of Role of Ngal in Diagnosis and Staging the Severity of Diabetic Nephropathy in Type 2 Diabetes Mellitus Patients in Sms Medical College, Jaipur.

J Assoc Physicians India 2022 Apr;70(4):11-12

Sms Medical College, Jaipur.

Present work was conducted to study of role of NGAL in diagnosis and staging the severity of diabetic nephropathy in type 2 diabetes mellitus patients to assess serum NGAL, urine albumin levels in diabetic patients with and without apparent nephropathy.

Material: Comparative study conducted in the General Medicine department of SMS Hospital.

Inclusion Criteria: Patients of type 2 Diabetes mellitus. Read More

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Factors associated with preterm birth among mothers who gave birth at public Hospitals in Sidama regional state, Southeast Ethiopia: Unmatched case-control study.

PLoS One 2022 20;17(4):e0265594. Epub 2022 Apr 20.

College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.

Background: Preterm birth remains the commonest cause of neonatal mortality, and morbidity representing one of the principal targets of neonatal health care. Ethiopia is one of the countries which shoulder the highest burden of preterm birth. Therefore, this study was aimed to assess factors associated with preterm birth at public hospitals in Sidama regional state. Read More

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Adherence to the Mediterranean Diet in Pregnancy and Its Benefits on Maternal-Fetal Health: A Systematic Review of the Literature.

Front Nutr 2022 31;9:813942. Epub 2022 Mar 31.

Department of Nursing, University of Alicante, Alicante, Spain.

Introduction: Pregnancy is a transcendent period for the mother and the fetus, characterized by an increase on energy requirements. Mediterranean diet (MD) is considered a healthy eating pattern that can provide the nutritional requirements of pregnancy and protect from the development of obstetric pathologies.

Objective: To know the relationship between adherence to the MD and its maternal-fetal benefits. Read More

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Tobacco Exposure During Pregnancy and Infections in Infants up to 1 Year of Age: The Japan Environment and Children's Study.

J Epidemiol 2022 Apr 9. Epub 2022 Apr 9.

Fukushima Regional Center for the Japan Environmental and Children's Study.

Background: Tobacco exposure during pregnancy is associated with several adverse outcomes in infants. We investigated the association between tobacco exposure during pregnancy (both active and second-hand) and various infections in infants up to 1 year.

Methods: This prospective cohort study used a fixed dataset (jecs-an-20180131) from the Japan Environment and Children's Study of registered births in Japan during 2011-2014 that included 104,065 fetal records from enrolled pregnant women. Read More

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Virulence gene mutations as a differentiator of clinical phenotypes: insights from community-acquired uropathogenic .

Microbiology (Reading) 2022 04;168(4)

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

Uropathogenic (UPEC) remains an important cause of urinary tract infection during pregnancy. Multiple molecular virulence determinants and antibiotic resistant genes facilitate its pathogenesis and virulence phenotype. Hence it is hypothesized that there will be considerable variation in genes among the isolates from symptomatic as well as asymptomatic bacteriuria (ABU) during pregnancy. Read More

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Estimation of invasive Group B Streptococcus disease risk in young infants from case-control serological studies.

BMC Med Res Methodol 2022 03 27;22(1):85. Epub 2022 Mar 27.

Statistics and Decision Sciences, Janssen Pharmaceuticals R & D, High Wycombe, United Kingdom.

Background: Group B Streptococcus (GBS) infections are a major cause of invasive disease (IGbsD) in young infants and cause miscarriage and stillbirths. Immunization of pregnant women against GBS in addition to intrapartum antibiotic prophylaxis could prevent disease. Establishing accurate serological markers of protection against IGbsD could enable use of efficient clinical trial designs for vaccine development and licensure, without needing to undertake efficacy trials in prohibitively large number of mother-infant dyads. Read More

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Reduction of intrapartum antibiotic prophylaxis by combining risk factor assessment with a rapid bedside intrapartum polymerase chain reaction testing for group B streptococci.

Eur J Obstet Gynecol Reprod Biol 2022 May 18;272:173-176. Epub 2022 Mar 18.

Department of Gynecology and Obstetrics, Kolding Sygehus, University Hospital of Southern Denmark, Sygehusvej 24, 6000 Kolding, Denmark.

Objective: To investigate the impact of administering Intrapartum Antibiotic Prophylaxis (IAP) to laboring women with one or more risk factors for Early Onset Group B Streptococcal neonatal infection (EOGBS) based on the result of a rapid bedside test for Group B Streptococci (GBS).

Study Design: Quality assessment study.

Methods: Three-hundred-sixty-six laboring women admitted to our maternity ward, with one or more risk factors for EOGBS, were prospectively included. Read More

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PECULIARITIES OF DISTRIBUTION OF ANTIBIOTIC RESISTANT STRAINS OF E. COLI - E. FAECALIS ASSOCIATION IN THE UROGENITAL TRACT OF PREGNANT WOMEN.

Wiad Lek 2022 ;75(2):462-468

OLES HONCHAR DNIPRO NATIONAL UNIVERSITY, DNIPRO, UKRAINE.

Objective: The aim: To investigate the prevalence of antibiotic-resistant strains from the association of E. coli - E. faecalis in the urogenital tract of pregnant women. Read More

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Adolescent pregnancy outcomes at Queen Elizabeth Central Hospital, Malawi: a cross-sectional study.

Malawi Med J 2021 12;33(4):261-268

Kamuzu University of Health Sciences, Malawi.

Malawi has a growing population with a high Maternal Mortality Ratio (MMR) of 439 per 100,000 live births to which adolescents contribute 25%. Current data suggests adolescent pregnancies in low resource settings are at an increased risk of both maternal and neonatal morbidity.

Objectives: This study assessed the pregnancy outcomes amongst adolescents while using women from the early adulthood (20 - 24-year-old) and advanced maternal age (35 years old and above) groups as reference. Read More

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December 2021

Maternal and neonatal outcomes among pregnant women with inflammatory myopathies.

J Perinat Med 2022 Jun 14;50(5):587-594. Epub 2022 Mar 14.

Department of Obstetrics & Gynecology, Jewish General Hospital, McGill University, Montreal, QC, Canada.

Objectives: Pregnancy outcomes in women with inflammatory myopathies (IM) are not well studied. The purpose of this study is to evaluate the effects of IM on maternal and neonatal outcomes.

Methods: We conducted a retrospective cohort study using data from the Healthcare Cost and Utilization Project - Nationwide Inpatient Sample (HCUP-NIS) from 1999 to 2015. Read More

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Antimicrobial Resistance Pattern in E. coli Isolated from Placental Tissues of Pregnant Women in Low-Socioeconomic Setting of Pakistan.

Curr Microbiol 2022 Feb 5;79(3):83. Epub 2022 Feb 5.

Public Health and Microbiology Lab, Department of Biosciences, COMSATS University Islamabad, Park road, Tarlai Kalan, Islamabad, Pakistan.

Infections during pregnancy can culminate in adverse pregnancy outcomes, including preterm birth (PTB). Pakistan is among the top ten nations with high PTB-associated neonatal mortality rates, where access to prenatal as well as neonatal care is only afforded by the privileged few. Societal stigma further discourages women seeking healthcare for minor infections. Read More

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February 2022

Risk factors for renal scarring and clinical morbidity in children with high-grade and low-grade primary vesicoureteral reflux.

J Pediatr Urol 2022 Apr 8;18(2):225.e1-225.e8. Epub 2022 Jan 8.

Department of Pediatric Nephrology, St John's Medical College, St John's National Academy of Health Sciences, Bangalore, 560034, India. Electronic address:

Introduction: Primary vesicoureteral reflux (VUR) is associated with urinary tract infections (UTIs) and renal damage. However, the importance of early diagnosis of VUR has been questioned. Moreover, most studies have few patients with high-grade VUR. Read More

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Prevalence and antimicrobial susceptibility pattern of urinary tract infection among pregnant women attending Hargeisa Group Hospital, Hargeisa, Somaliland.

Sci Rep 2022 01 26;12(1):1419. Epub 2022 Jan 26.

Hawassa University College of Medicine and Health Science, Hawassa, Ethiopia.

The aim of this study was to determine the prevalence, antimicrobial susceptibility pattern and associated factors of urinary tract infection (UTI) among pregnant women attending Hargeisa Group Hospital (HGH), Hargeisa, Somaliland. A cross-sectional study was conducted at HGH, Hargeisa, Somaliland and participants were selected by systematic random sampling technique. Clean catch midstream urine samples were collected from 422 participants and cultured and antimicrobial susceptibility pattern was determined for the isolates. Read More

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January 2022

Solitary tubercular renal cyst in a postpartum lady masquerading as an infected giant renal cyst with urosepsis.

Indian J Pathol Microbiol 2022 Jan-Mar;65(1):170-172

Department of Urology, Sri Narayani Hospital and Research Centre, Vellore, Tamil Nadu, India.

Renal tuberculosis presenting as renal cyst is rare. Diagnosing renal tuberculosis in pregnancy is usually delayed due to its atypical presentation. We present a 28-year-old postpartum lady who delivered a healthy baby one month back, with history of intermittent fever and chills. Read More

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February 2022

How to avoid drug resistance during treatment and prevention of urinary tract infections.

Prz Menopauzalny 2021 Dec 9;20(4):217-221. Epub 2021 Dec 9.

1 Department of Obstetrics and Gynaecology, Medical University of Warsaw, Warsaw, Poland.

Urinary tract infections (UTIs), defined as the presence of bacteria above the bladder sphincter, are among the most common infectious diseases. They remain a significant cause of antibiotic prescription worldwide. The incidence is much higher among women, especially of reproductive age, than among men. Read More

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December 2021

Second Trimester Fetal Loss Due to Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM).

Diagnostics (Basel) 2022 Jan 10;12(1). Epub 2022 Jan 10.

Clinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy.

is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to spp. have been reported in the urinary tract, respiratory airways, intra-abdominal organs, skin and soft tissue, eye, bone, bloodstream, and central nervous system. Read More

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January 2022