730,879 results match your criteria Urinary Obstruction
Aktuelle Urol 2018 Dec 6;49(6):519-524. Epub 2018 Dec 6.
Spital Thurgau AG, Urologie, Frauenfeld.
The classical algorithm of the management of male lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH) includes a surgical approach in case pharmacological therapy has failed. Emerging minimally-invasive treatments (MITs) offer potential for rapid symptomatic relief, reducing the morbidity of invasive BPH surgery. Convective interstitial radiofrequency water vapour thermal ablation of the prostate with the Rezūm system is a novel MIT for the treatment of bothersome moderate-to-severe lower urinary tract symptoms associated with BPH. Read More
Horm Metab Res 2018 Dec 6. Epub 2018 Dec 6.
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.
Cross-sectional studies in small and selected populations report a high prevalence of hypercortisolism in patients with type 2 diabetes (T2D), which could have therapeutic implications, if confirmed. We therefore estimated the prevalence of hypercortisolism in a large and unselected cohort of recently diagnosed T2D patients. Consecutive patients with recently diagnosed T2D first underwent an overnight dexamethasone (1 mg) suppression test (OD). Read More
Cell Physiol Biochem 2018 Dec 6;51(5):2085-2097. Epub 2018 Dec 6.
Background/aims: Diabetic nephropathy is a common complication of diabetes. This study explored the renal protective effect and possible mechanism of gliquidone in mice with diabetic nephropathy.
Methods: Animal model of diabetic nephropathy was established in KKAy mice. Read More
Int J Surg Case Rep 2018 Nov 22;54:47-50. Epub 2018 Nov 22.
Department of General Surgery, King Abdulla University Hospital, Faculty of Medicine, Jordan University of Science and Technology, P.O. Box (3030), Irbid, 22110, Jordan. Electronic address:
Introduction: Sacrococcygealteratoma is very rare in adults with only few cases reported in literature. It is a slow growing benign cystic tumor with 1-2% chance for malignant transformation and may attain a huge size causing pressure effect on pelvic and intra-abdominal organs. When grows caudally, it causes discomfort, skin excoriation and cosmetic disfigurement. Read More
Biomed Pharmacother 2018 Dec 3;110:302-311. Epub 2018 Dec 3.
College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, PR China; Sichuan Neo-Green Pharmaceutical Technology Development Co., Ltd, Chengdu 610081, PR China. Electronic address:
Ethnopharmacological Relevance: Er Shen Wan (ESW), has been empirically used for treating spleen-kidney Yang deficiency (SKYD) syndrome in Traditional Chinese medicine (TCM) for centuries and shows a variety of activities. The medicinal formula is a mixture of two component herbs, Psoraleae Fructus (PF, Bu-Gu-Zhi in Chinese) and Myristicae Semen (MS, Rou-Dou-Kou in Chinese). The current study was designed to evaluate ESWP antidiuretic treatment of polyuria and to explore potential mechanisms of renal water metabolism in the rat model of SKYD-induced diarrhea. Read More
Atherosclerosis 2018 Nov 23;280:147-154. Epub 2018 Nov 23.
Department of Anesthesiology, Shuan Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan; Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:
Background And Aims: The risk of stroke in epileptic patients and the impact of epilepsy history on stroke patients' outcome have not been studied completely. Our purpose is to evaluate whether patients with epilepsy have increased risk of stroke or post-stroke mortality.
Methods: In Study I, we conducted a retrospective cohort study of 6746 patients with newly diagnosed epilepsy and 26,984 persons without epilepsy between 2000 and 2008, in the database of National Health Insurance in Taiwan. Read More
Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.
Jiangsu Key Laboratory of Marine Bioresources and Environment, Huaihai Institute of Technology, 59 Cangwu Road, Haizhou 222005, China; Co-Innovation Center of Jiangsu Marine Bio-industry Technology, 59 Cangwu Road, Haizhou 222005, China; Jiangsu Key Laboratory of Marine Biotechnology, 59 Cangwu Road, Haizhou 222005, China. Electronic address:
A mulberry leaf polysaccharide (MLP-1) was prepared and partially characterised, and its anti-renal-fibrosis effects were investigated in streptozotocin (STZ)-induced diabetic nephropathy (DN) rats. MLP-1, with a molecular weight of 2,792,624 Da, consisted of arabinose, glucose, xylose, rhamnose, and mannose in a molar ratio of 1:1.13:2. Read More
Res Microbiol 2018 Dec 3. Epub 2018 Dec 3.
Department of Biology of Bacteria, Faculty of Biology and Environmental Protection, University of Łódź, Banacha 12/16, 90-237 Łódź, Poland. Electronic address:
Infectious urolithiasis is a consequence of long-standing urinary tract infections with urease-positive bacteria, especially Proteus spp. However, because of the often mixed nature of urinary tract infections, in the case of urinary stones formation, several species of bacteria may be involved in the process. The purpose of the study was to determine the impact of the bacterial species: Escherichia coli, Klebsiella pneumoniae, Providencia stuartii, Pseudomonas aeruginosa and Staphylococcus aureus on the crystallization caused by Proteus mirabilis. Read More
Acta Ortop Mex 2018 May-Jun;32(3):126-130
Centro de Evaluación de Tecnologías, Universidad CES, Medellín, Colombia.
Introduction: Cephalomedullary nails are used for the treatment of hip fractures; however, there are few studies that allow identifying data on the complications of the use of these devices and the results in terms of restoration of the functionality of the patient.
Methods: A cross-sectional study of patients with femur fracture was conducted during the period from January 2008 to December 2012. Data on demographic and clinical variables were collected. Read More
Expert Opin Biol Ther 2018 Dec 6. Epub 2018 Dec 6.
e Chair of Urology, Department of Regenerative Medicine, Collegium Medicum , Nicolaus Copernicus University , Bydgoszcz , Poland ;
Introduction: In reconstructive urology, autologous tissues such as intestinal segments, skin, and oral mucosa are used. Due to their limitations, reconstructive urologists are waiting for a novel material, which would be suitable for urinary tract wall replacement. Human amniotic membrane (AM) is a naturally derived biomaterial with a capacity to support reepithelization and inhibit scar formation. Read More
Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):347-353. Epub 2018 Nov 30.
Instituto Mexicano del Seguro Social, Hospital General de Zona No. 33, Departamento de Urología. Monterrey, Nuevo León, México
Background: The urinary tract infections are the third cause of infections in Mexico. The inappropriate use of antibiotic has generated the presence of multidrugresistant bacteria.
Objective: To identify the bacterial resistance patterns of the hospital and to detect the present comorbidities that can modify the evolution of urinary tract infection for proper empirical management. Read More
Int Braz J Urol 2018 Oct 30;44. Epub 2018 Oct 30.
Department of Neuro-Urology, CTO - Spinal Unit, Città della Salute e della Scienza di Torino, Turin, Italy.
Purpose: The aim of our study is to evaluate the efficacy and safety of ATOMS® system for the treatment of postoperative male stress urinary incontinence (SUI).
Materials And Methods: We retrospectively evaluated all patients treated at our institution for postoperative male SUI with ATOMS® implant. We excluded patients with low bladder compliance (< 20 mL / cmH2O), uncontrolled detrusor overactivity, detrusor underactivity (BCI < 100), urethral or bladder neck stricture and low cystometric capacity (< 200 mL). Read More
Int Braz J Urol 2018 Oct 20;44. Epub 2018 Oct 20.
Department of Urology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Introduction: Endometriosis consists in the proliferation of endometrial tissue outside of the uterine cavity, predominantly in the ovaries but also in the urinary bladder or bowel. About 10% of fertile women are affected and the main symptoms are pain, menstrual disorders and infertility. Surgery is the treatment option for those symptomatic patients in which medical treatment had no success. Read More
Int Braz J Urol 2018 Oct 30;44. Epub 2018 Oct 30.
Department of Urology, University of Pittsburgh, Pennsylvania, U.S.A.
Purpose: To describe the clinical characteristics, treatment patterns, and outcomes in patients with small cell bladder cancer at our institution, including those who received prophylactic cranial irradiation (PCI) for the prevention of intracranial recurrence.
Materials And Methods: Patients with small cell bladder cancer treated at a single institution between January 1990 and August 2015 were identified and analyzed retrospectively for demographics, tumor stage, treatment, and overall survival.
Results: Of 44 patients diagnosed with small cell bladder cancer, 11 (25%) had metastatic disease at the time of presentation. Read More
JBRA Assist Reprod 2018 Dec 6. Epub 2018 Dec 6.
Fertipraxis-Centro de Reprodução Humana- RJ, Brazil.
Introduction: More than one million fertilization cycles are performed every year. The incidence of serious complications associated with transvaginal oocyte pick-up is low, but the procedure is not risk-free. Risks are inherent to procedures in which thin needles and sharp instruments are introduced into the vaginal wall and ovarian capsule to access the ovaries. Read More
Chemistry 2018 Dec 6. Epub 2018 Dec 6.
Kings College London, Department of Imaging Chemistry and Biology, St Thomas' Hospital, SE1 7EH, London, UNITED KINGDOM.
Aldehyde dehydrogenases (ALDHs) catalyze the oxidation of aldehydes to carboxylic acids, with elevated ALDH expression in human cancers linked to metastases and poor overall survival. Despite ALDH being a poor prognostic factor, the non-invasive assessment of ALDH activity in vivo has not been possible due to a lack of sensitive and translational imaging agents. In this report, we present the synthesis and biological evaluation of ALDH1A1-selective chemical probes composed of an aromatic aldehyde derived from N,N-diethylamino benzaldehyde (DEAB) linked to a fluorinated pyridine ring either via an amide or amine linkage. Read More
J Intern Med 2018 Dec 6. Epub 2018 Dec 6.
Division of Surgery & Interventional Science, University College London, London, UK.
Background: A lack of consensus exists among national guidelines regarding who should be investigated for haematuria. Type of haematuria and age specific thresholds are frequently used to guide referral for investigation of haematuria.
Objectives: To develop and externally validate the haematuria cancer risk score (HCRS) to improve patient selection for investigation of haematuria. Read More
Nephrol Dial Transplant 2018 Dec 5. Epub 2018 Dec 5.
National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, China.
Background: Recent data suggest that miR-196a is predominantly expressed in the kidney and plays an inhibitory role in the progress of renal interstitial fibrosis (IF). However, the predictive value of miR-196a in diabetic nephropathy (DN) remains unknown. We validated the role of urinary miR-196a in the progression of renal injury in a cohort of patients with type 2 diabetes mellitus. Read More
Ther Drug Monit 2018 Dec 4. Epub 2018 Dec 4.
Department of Pharmacy, Shanghai Changhai Hospital, Second Military Medical University, Shanghai (200433), China.
Background: Kidney transplant recipients on long-term cyclosporine (CsA) therapy may develop multiple adverse drug events, and immunosuppression conversion from CsA to tacrolimus (Tac) is an option. Genetic variations, especially cytochrome P450 (CYP) 3A5*3 affects Tac dosing. However, little information is available to guide the conversion with regards to patients' pharmacogenomics. Read More
Female Pelvic Med Reconstr Surg 2018 Dec 5. Epub 2018 Dec 5.
From the Division of Female Pelvic Medicine and Reconstructive Surgery, Indiana University, Indianapolis, IN.
Bladder compliance refers to the ability of the bladder to accommodate large volumes of urine. Patients with low bladder compliance may present with persistent urinary incontinence and/or evidence of upper tract damage. Clinicians often may not consider low bladder compliance in their differential for patients complaining of bothersome lower urinary tract symptoms. Read More
Curr Pharm Biotechnol 2018 Dec 5. Epub 2018 Dec 5.
Department of Food Science & Nutrition, School of Environment, University of the Aegean, Lemnos. Greece.
Introduction: Urinary tract infections (UTIs) represent a common and costly public health issue. The bacterium Escherichia coli is mainly responsible for most uncomplicated UTIs. Cranberry antibacterial effects have extensively been studied in order to understand the molecular mechanisms of action of its bioactive components and their clinical benefits against UTIs. Read More
J Cosmet Dermatol 2018 Dec 5. Epub 2018 Dec 5.
Faculty of Medicine, Benha University, Benha, Egypt.
Background: Androgenetic alopecia carries a major cosmetic disfigurement and benign prostatic hyperplasia is associated with many urinary tract symptoms and both diseases are mediated by dihydrotestosterone.
Objectives: The study aimed to determine the relationship between hair diameter in androgenetic alopecia diagnosed, by trichoscope, to benign prostatic hyperplasia symptoms and signs.
Methods: Fifty androgenetic alopecia males and 50 normal males as control were included. Read More
Diabetes Obes Metab 2018 Dec 5. Epub 2018 Dec 5.
Medical School, University of Western Australia, and Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Perth, Western Australia, Australia.
Background: Low circulating testosterone is associated with an increased risk of developing type 2 diabetes (T2DM) in overweight men with impaired glucose tolerance (IGT).
Aim: To determine in a multi-centre, double-blinded placebo-controlled randomised trial, whether testosterone treatment combined with lifestyle intervention (Weight Watchers®) relative to lifestyle intervention alone, reduces T2DM incidence and improves glucose tolerance at 2 years.
Study Population: Overweight or obese men aged 50-74 years with a serum testosterone of ≤14nmol/L and IGT or newly diagnosed T2DM established by an oral glucose tolerance test (OGTT). Read More
Int Urol Nephrol 2018 Dec 5. Epub 2018 Dec 5.
Nephrology Division, New York University Langone Medical Center, New York, NY, USA.
Purpose: The purpose of the study was to assess the differences in the concentration and function of urinary proteins between patients with cystine stones (CYS) and healthy controls (HC). We postulated that CYS and HC groups would demonstrate different proteomic profiles.
Methods: A pilot study was performed comparing urinary proteomes of 10 patients with CYS and 10 age- and gender-matched HC, using liquid chromatography-mass spectrometry. Read More
Inflammation 2018 Dec 5. Epub 2018 Dec 5.
Department of Nephrology, Affiliated Hospital of Southwest Medical University, No. 25, Tai Ping Street, Jiangyang District, 646000, Luzhou, China.
Schisandrin B (SchB) is an active compound extracted from the Chinese herb Schisandra chinensis and shows excellent anti-inflammatory activity. This study was performed to examine the effects of SchB in a rat model of IgA nephropathy (IgAN). IgAN was established in Sprague-Dawley rats by immunization with lipopolysaccharide (LPS), bovine serum albumin, and carbon tetrachloride. Read More
Eur J Clin Microbiol Infect Dis 2018 Dec 5. Epub 2018 Dec 5.
Old Medical School, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds, LS1 3EX, UK.
Standard bolus-dosed antibiotic prophylaxis may not inhibit growth of antibiotic resistant colonic bacteria, a cause of SSIs after colorectal surgery. An alternative strategy is continuous administration of antibiotic throughout surgery, maintaining concentrations of antibiotics that inhibit growth of resistant bacteria. This study is a pilot comparing bolus-continuous infusion with bolus-dosed cefuroxime prophylaxis in colorectal surgery. Read More
Patient 2018 Dec 6. Epub 2018 Dec 6.
Astellas Pharma Inc., Northbrook, IL, USA.
Background: There is little information available on health-related quality of life in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer. This study aimed to develop a conceptual model that describes patients' experiences of living with this condition.
Methods: This was a cross-sectional, non-interventional qualitative research study. Read More
Radiologe 2018 Dec 5. Epub 2018 Dec 5.
Universitätsinstitut für Radiologie, Universitätsklinikum der Paracelsus Medizinischen Privatuniversität, Müllner Hauptstraße 48, 5020, Salzburg, Österreich.
Background: Acute pelvic pain in women may be due to gynecological, gastrointestinal, and urinary tract disorders. Ectopic pregnancy (EP), pelvic inflammatory disease (PID), and ruptured ovarian cysts are the most common gynecological causes for acute pelvic pain and their diagnosis can be challenging.
Methods: Patient history, clinical examination, and blood tests as well as patient age and potential pregnancy status help to establish the correct diagnosis. Read More
World J Urol 2018 Dec 5. Epub 2018 Dec 5.
USC Institute of Urology, Keck Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Objectives: To determine and investigate the intraoperative factors that contribute to a change in plan from continent orthotopic neobladder to ileal conduit or continent cutaneous diversion at the time of radical cystectomy.
Subjects And Methods: A retrospective review of our prospectively maintained bladder cancer database was performed. Of the 711 patients who underwent radical cystectomy from 2012 to 2016, 387 (54. Read More
Arch Orthop Trauma Surg 2018 Dec 5. Epub 2018 Dec 5.
Department of Orthopaedic and Trauma Surgery, Robert-Bosch-Krankenhaus Stuttgart, Auerbachstrasse 110, 70376, Stuttgart, Germany.
Objective: The objective of the current study was to evaluate the effect of a quality management system on treatment and care delivery of proximal femoral fractures. Specifically, our hypothesis was that the "plan-do-check-act (PDCA)" philosophy of the ISO 9001 quality management system results in a continuous improvement process.
Methods: 1015 proximal femoral fractures were prospectively included into a hip fracture database over a 5-year period, after a restructuring process with implementation of clinical pathways and standard operation procedures. Read More
Open Med (Wars) 2018 27;13:597-604. Epub 2018 Nov 27.
Institute of Pathology, Basic Medical College of Lanzhou University, Lanzhou 730000, Gansu Province, China.
Objective: To investigate the clinical pathology and prognosis & outcome of Henoch-Schonlein purpura nephritis (HSPN) with renal interstitial lesions.
Methods: All 148 patients were analyzed for clinical, renal pathological, and prognostic features. Patients with no, mild, and moderate- severe renal tubulo-interstitial lesions were included in group A, B and C, respectively. Read More
Biomed Res Int 2018 5;2018:1607425. Epub 2018 Nov 5.
2nd Department of Gynaecology, Medical University of Lublin, Lublin, Poland.
Aim: The aim of this observational study was to evaluate the effectiveness of a phytotherapic drug (Canephron N) in preventing urinary tract infection (UTI) in high-risk women undergoing urodynamic studies (UDS).
Methods: The study protocol was approved by the local institutional ethical committee. Adult women with at least one risk factor for acquiring UTI (defined as: age over 70, elevated postvoid residual urine>100 ml, recurrent UTI, pelvic organ prolapse (POP) ≥II in POP-Q scale, and neurogenic bladder) had received after UDS either a single oral dose of fosfomycin trometamol (FT) (3 grams) or a phytodrug containing centaury herb, lovage root, and rosemary leaves (5 ml taken orally three times daily for one week). Read More
Toxicol Rep 2019 20;6:18-25. Epub 2018 Nov 20.
PMI R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, CH-2000, Neuchâtel, Switzerland.
Background: To evaluate the reduced-risk potential of alternative tobacco products, biomarkers that are involved in the biological pathways affected by cigarette smoking and smoking cessation are needed. Isoprostanes, a measure of oxidative stress, appear to be influenced by smoking and reversible upon smoking cessation and therefore could be a good biomarker. This review aims at quantifying the effect of smoking and smoking cessation on levels of urinary 8-iso prostaglandin F (8-epi-PGF), an isoprostane. Read More
Integr Med Res 2018 Dec 26;7(4):307-315. Epub 2018 Oct 26.
Department of Amraze Niswan wa Ilmul Qabalat (Gynecology and Obstetrics), National Institute of Unani Medicine, Bengaluru, India.
Background: It is not only to evaluate the efficacy and safety of mace (Arils of Houtt) but also to compare pelvic floor muscle training vs. pelvic floor muscle training (PFMT) for improving symptoms and health-related quality of life (HRQoL) of woman with mixed urinary incontinence (MUI).
Methods: A prospective, single-blind randomized controlled study was conducted. Read More
Case Rep Urol 2018 4;2018:6183618. Epub 2018 Nov 4.
West Virginia University, Department of OB/GYN, Morgantown, WV, USA.
A urethral diverticulum is a relatively uncommon finding. The estimated prevalence is approximately 1-5% in the general population. While the definitive treatment is surgical correction, there are limited studies guiding the best approach to repair. Read More
Stand Genomic Sci 2018 29;13:35. Epub 2018 Nov 29.
1Center of Food Safety and Applied Nutrition, U. S. Food and Drug Administration, 8301 Muirkirk Road, Laurel, MD 20708 USA.
is a Gram-negative opportunistic pathogen that causes life- threatening infantile infections, such as meningitis, septicemia, and necrotizing enterocolitis, as well as pneumonia, septicemia, and urinary tract and wound infections in adults. Here, we report 26 draft genome sequences of , which were obtained from dried spices from the USA, the Middle East, China, and the Republic of Korea. The average genome size of the genomes was 4393 kb, with an average of 4055 protein coding genes, and an average genome G + C content of 56. Read More
Biomicrofluidics 2018 Nov 13;12(6):064102. Epub 2018 Nov 13.
Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan.
In this study, we have developed a novel paper based immunoassay for the quantitative detection of immunoreactions using electrochemical impedance spectroscopy. Paper provides an attractive platform for fabrication of simple, low cost, and portable diagnostic devices as it allows passive liquid transport, is biocompatible, and has tunable properties such as hydrophilicity, flexibility, permeability, and reactivity. We have used screen-printing to fabricate interdigitated electrodes (finger width and gap of 200 m) on the paper substrate, while UV-lithography enables patterning of the paper into hydrophobic/hydrophilic regions. Read More
J Cancer 2018 22;9(23):4391-4397. Epub 2018 Oct 22.
Department of Urinary Surgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221000, China.
Purpose: Oncolytic adenoviruses emerge as new agents for cancer therapy. This study aimed to investigate the synergistic anti-tumor activity of oncolytic adenovirus armed with IL-24 (ZD55-IL-24) and docetaxel (DTX) on advanced prostate cancer and .
Methods: DU145 prostate cancer cells or nude mice xenografted with DU145 prostate cancer cells were treated by ZD55-IL-24 and DTX alone or in combination. Read More
Evid Based Complement Alternat Med 2018 5;2018:5968657. Epub 2018 Nov 5.
Suzhou Academy of Wumen Chinese Medicine, Suzhou 215000, China.
Objectives: To investigate the mechanism of the protective effect of Zishenwan on pyelonephritis rats.
Methods: In the rat model of pyelonephritis, protective effects of Zishenwan, the content of secretory immunoglobulin A (SIg A), and interleukins were detected by ELISA. The expressions of TLR4-NFB pathway were detected by Western blot in renal and urinary tract mucosa. Read More
Evid Based Complement Alternat Med 2018 5;2018:5059267. Epub 2018 Nov 5.
Clinical Medical College, Yunnan University of Traditional Chinese Medicine, Kunming 650051, China.
Qianlie Tongqiao Capsule (QTC) is clinically confirmed to be efficacious and safe in treating lower urinary tract syndromes and bladder dysfunction that are induced by benign prostatic hyperplasia (BPH). However, the functional mechanisms of QTC remain unclear. We aim to investigate the effects of QTC on both bladder weight and several growth factors in the bladder tissue of rats with testosterone-induced BPH. Read More
BMC Clin Pathol 2018 28;18:13. Epub 2018 Nov 28.
Department of Pathology, Military General Hospital Mohammed V, Mohammed V- Souissi University, Hay Riad, 10000 Rabat, Morocco.
Background: Urinary schistosomiasis is a common parasitic disease in endemic countries.
Case Presentation: We report the case of a patient who was on a working trip to Mauritania. This parasitosis, suspected in the presence of hematuria and the notion of stay in an endemic zone, was confirmed by the presence of Schistosoma heamatobium eggs during the histological examination of the bladder biopsy performed after cystoscopy, highlighting a bilharzial granuloma and of course, the diagnosis was confirmed by the presence of eggs during the direct examination of the freshly collected urine. Read More
J Expo Sci Environ Epidemiol 2018 Dec 5. Epub 2018 Dec 5.
Summit Toxicology, LLP, Bozeman, MT, USA.
Exposure models provide critical information for risk assessment of personal care product ingredients, but there have been limited opportunities to compare exposure model predictions to observational exposure data. Urinary excretion data from a biomonitoring study in eight individuals were used to estimate minimum absorbed doses for triclosan and methyl-, ethyl-, and n-propyl- parabens (TCS, MP, EP, PP). Three screening exposure models (European Commission Scientific Commission on Consumer Safety [SCCS] algorithms, ConsExpo in deterministic mode, and RAIDAR-ICE) and two higher-tier probabilistic models (SHEDS-HT, and Creme Care & Cosmetics) were used to model participant exposures. Read More
Tohoku J Exp Med 2018 ;246(4):205-212
Department of Orthopedic, Traditional Chinese Medicine Hospital of Puning City, Orthopaedic Hospital of Puning City.
Hip fracture is a worldwide medical problem with devastating consequences. Older adults are at higher risk for complications and have more mobility limitation. The aim of this study was to assess the impact of delay in out-of-bed functional exercise on one-year mortality and functional outcomes for elderly patients with hip fracture in China. Read More
BMJ Evid Based Med 2018 Dec 5. Epub 2018 Dec 5.
Department of General Practice, Medical School Hannover, Hannover, Germany.
BMJ Evid Based Med 2018 Dec 5. Epub 2018 Dec 5.
Department for General Practice, Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany.
BMC Infect Dis 2018 Dec 5;18(1):626. Epub 2018 Dec 5.
University Medical Centre Utrecht, University of Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.
Background: Febrile Urinary Tract Infection (FUTI) is frequently treated initially with intravenous antibiotics, followed by oral antibiotics guided by clinical response and bacterial susceptibility patterns. Due to increasing infection rates with multiresistant Enterobacteriaceae, antibiotic options for stepdown treatment decline and patients more frequently require continued intravenous antibiotic treatment for FUTI. Fosfomycin is an antibiotic with high bactericidal activity against Escherichia coli and current resistance rates are low in most countries. Read More
J Biol Regul Homeost Agents 2018 Dec 6;32(6). Epub 2018 Dec 6.
Andrological Urological Private Practice, Palermo, Italy.
Benign prostatic hyperplasia (BPH) is one of the most common conditions affecting men over 40 years of age, typically manifesting itself with lower urinary tract symptoms (LUTS). Recently, research interest has focused in discovering a viable nutraceutical alternative to the drugs that are currently the first line of treatment for BPH. The aim of this study was to investigate the efficacy and safety of a dietary supplement containing curcumin, beta-sitosterol and oligomeric proanthocyanidins in a group of BPH/LUTS patients. Read More
Nutrients 2018 Dec 4;10(12). Epub 2018 Dec 4.
School of Agriculture and Food Science, Institute of Food and Health, University College Dublin, Belfield, Dublin 4, Ireland.
A significant body of evidence demonstrates that isoflavone metabolites are good markers of soy intake, while research is lacking on specific markers of other leguminous sources such as peas. In this context, the objective of our current study was to identify biomarkers of pea intake using an untargeted metabolomics approach. A randomized cross-over acute intervention study was conducted on eleven participants who consumed peas and couscous (control food) in random order. Read More
Rev Prat 2016 Nov;67(9):998-1000
Service de gynécologieobstétrique, hôpital Beaujon, AP-HP, Clichy, France.
Iodine deficiency during pregnancy. Iodine is a necessary element to thyroid hormones synthesis, and is essential in neurological development. Iodine needs increases during pregnancy. Read More
Fortschr Neurol Psychiatr 2018 Dec 3. Epub 2018 Dec 3.
Marien Hospital Herne, Universitätsklinikum der Ruhr- Universität Bochum, Abteilung für Neuro-Urologie.
An overactive neurogenic detrusor and an non-neurogenic overactive bladder both exhibit symptoms such as urgency and frequency, both with and without urinary incontinence, and are often accompanied by nocturia. OnabotulinumtoxinA-Detrusorinjection has become well established as a second line therapy in cases where anticholinergic medication has failed. The procedure can be performed under general or local anesthesia, in both in- and outpatient settings. Read More