31,713 results match your criteria Urinary Obstruction

Long-term urological complications after conservative local treatment (surgery and brachytherapy) in children with bladder-prostate rhabdomyosarcoma: A single-team experience.

Pediatr Blood Cancer 2022 Aug 6;69(8):e29532. Epub 2022 Jan 6.

Department of Pediatric Surgery, Bicêtre Hospital, Assistance Publique-Hôpitaux de Paris, Paris-Saclay University, Le Kremlin-Bicêtre, France.

Background: Outcome of children with bladder-prostate rhabdomyosarcoma (RMS) has improved with multimodal therapies, including surgery and/or radiotherapy for local treatment. Our aim was to report long-term urological complications after a conservative approach combining conservative surgery and brachytherapy.

Patients And Methods: Eighty-six patients, free of disease, were retrospectively reviewed. Read More

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Pelviureteric Junction Obstruction Due to Vascular Anomalies in Children - Simple Surgical Options.

J Indian Assoc Pediatr Surg 2022 May-Jun;27(3):297-303. Epub 2022 May 12.

Department of Paediatric Surgery, St. John's Medical College, Bengaluru, Karnataka, India.

Aims: Pelviureteric junction obstruction (PUJO) due to aberrant lower polar artery is conventionally managed with pyeloplasty. We present our experience of managing PUJO due to "vascular" anomalies-aberrant lower polar artery and vascular adhesions with simpler surgical options.

Subjects And Methods: This is a protocol based, retrospective study of PUJO. Read More

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Acute and late toxicity of prostate-only or pelvic SBRT in prostate cancer: A Comparative Study.

Int J Radiat Oncol Biol Phys 2022 Jun 17. Epub 2022 Jun 17.

Department of Medical Physics, Tata Memorial Hospital and Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Homi Bhabha National Institute (HBNI), Mumbai, India.

Objective: To compare the urinary and gastrointestinal toxicity with or without the inclusion of pelvic nodal regions in patients treated with extreme hypofractionated stereotactic radiotherapy (SBRT) for prostate cancer.

Methods: Patients treated with definitive SBRT for non-metastatic adenocarcinoma prostate were identified from prospectively maintained institutional database, and details of radiotherapy volume, dose, acute and late adverse effects were analyzed. Symptoms of acute (within 90 days of completing SBRT) and late gastrointestinal and urinary toxicities were graded using CTCAE version 5. Read More

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Transabdominal laparoscopy and ureteroscopy one-stage surgery in the treatment of bilateral ureteropelvic junction obstruction combined with bilateral renal stones: A case report.

Exp Ther Med 2022 Jul 17;24(1):450. Epub 2022 May 17.

Department of Urology, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei 056004, P.R. China.

Ureteropelvic junction obstruction (UPJO) is a common congenital malformation of the urinary system, which is mostly unilateral and frequently combined with hydronephrosis and kidney stones. The incidence of kidney stones is ~20%, which markedly increases the difficulty and risk of surgery. The present report describes a rare case of bilateral UPJO combined with bilateral renal stones. Read More

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Multiple Bladder Diverticula Presenting in an 82-Year-Old Congolese Male.

Case Rep Surg 2022 10;2022:9295861. Epub 2022 Jun 10.

Faculty of Medicine, Catholic University of Bukavu, Bukavu, Democratic Republic of the Congo.

Bladder diverticulum is a congenital malformation characterized by the outpouching of the bladder following an obstruction of urine flux. We present a case of 82-year-old Congolese male patient presented at our facility with a poor urinary stream and lower abdominal pain. A distended abdomen was found on physical examination while the external genitalia were normal. Read More

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Use of the penile cuff test to diagnose bladder outlet obstruction: A systematic review and meta-analysis.

Low Urin Tract Symptoms 2022 Jun 18. Epub 2022 Jun 18.

Department of Urology, Weill Cornell Medical College, New York, New York, USA.

Purpose: Among noninvasive modalities for assessing bladder outlet obstruction (BOO), the penile cuff test (PCT) is the most used in clinical practice. The purpose of this review was to evaluate the performance of PCT in diagnosing and managing BOO.

Materials And Methods: PubMed, Scopus, CINAHL, Embase, Cochrane Library, and Web of Science were searched for studies investigating use of PCT for BOO. Read More

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Gangrenous Small Bowel Due to Reposition of Procidentia in an Elderly Woman.

Cureus 2022 May 15;14(5):e25013. Epub 2022 May 15.

General Surgery, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Gynecologists are familiar with procidentia, a severe form of pelvic organ prolapse (POP) that includes herniation of the anterior, posterior, and apical compartments of the vagina, through the introitus. Usually, women with POP present with concerns of something coming out of the vagina, heaviness, discharge through the vagina, urinary complaints, and, rarely bowel, complaints. Intestinal obstruction secondary to procidentia is a rare complication and is seldom reported in the literature. Read More

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Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India.

Urol Ann 2022 Apr-Jun;14(2):125-131. Epub 2022 Feb 15.

Department of Urology and Renal Transplantation, JIPMER, Puducherry, India.

Introduction: Video urodynamic study (VUDS) with clinical correlation helps in diagnosing primary bladder neck obstruction (PBNO) in women. Bladder neck incision/bladder neck resection (BNR) though effective is not commonly practiced for the fear of complications and limited literature available.

Methods: The records of ten women diagnosed with PBNO between 2017 and 2019 were reviewed and data pertaining to their clinical features, laboratory results, findings on abdominal ultrasonography, uroflowmetry, and VUDS was noted. Read More

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February 2022

Fluoroscopy-guided trans-urethral exchange of double-J ureteral stents.

BMC Urol 2022 Jun 15;22(1):85. Epub 2022 Jun 15.

Department of Radiology, Korea University Anam Hospital, 73, Goryeodae-ro, Seongbuk-gu, Seoul, Korea.

Background: For patients with malignant ureteral obstruction or stricture who require long-term internal drainage, plastic double-J stents (DJ stents) represent the mainstay of therapeutic strategies. DJ stents should be replaced at least once every 6 months to avoid infection or obstruction. Although DJ stents are generally replaced under cystoscopy, successful fluoroscopy-guided retrograde replacement of DJ stents in the interventional suite has been described in the literature. Read More

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Proteome analysis of urinary biomarkers in a cigarette smoke-induced COPD rat model.

Respir Res 2022 Jun 15;23(1):156. Epub 2022 Jun 15.

Department of Biochemistry and Molecular Biology, Gene Engineering Drug and Biotechnology Beijing Key Laboratory, Beijing Normal University, Beijing, 100875, China.

Background: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory airway disease caused by inhalation of cigarette smoke (CS) and other harmful gases and particles.

Methods: This study aimed to explore potential urinary biomarkers for CS-induced COPD based on LC-MS/MS analysis.

Results: A total of 340 urinary proteins were identified, of which 79 were significantly changed (30, 31, and 37 at week 2, 4 and 8, respectively). Read More

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Large Bowel Obstruction Secondary to Urinary Retention.

Acta Med Acad 2022 Apr;51(1):64-65

Catholic Health System, Sisters of Charity Hospital, Buffalo, New York, USA.

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Ureteroenteric Stricture Outcomes: Secondary analysis of an RCT comparing open vs robotic cystectomy.

BJU Int 2022 Jun 13. Epub 2022 Jun 13.

Urology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Objectives: To analyze the risk of ureteroenteric anastomotic stricture in patients randomized to open or robotic cystectomy with extracorporeal urinary diversion.

Patients And Methods: We included 118 patients randomized to robotic (n=60) or open (n=58) cystectomy at a single, high-volume institution from March 2010 to April 2013. Urinary diversion was performed by experienced open surgeons. Read More

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Upper pole pathologies in duplex kidneys: an analysis of predictive factors for surgery and urinary tract infections from the Mid-Atlantic Pediatric Academic Consortium.

J Pediatr Urol 2022 May 29. Epub 2022 May 29.

Department of Urology, University of Virginia, Charlottesville, VA, USA. Electronic address:

Background/objective: While there is significant data on the natural history and outcomes for prenatal hydronephrosis in simplex kidneys, duplex kidneys tend to be less studied. Management can be quite variable based on provider preference. We aimed to describe practice patterns from several tertiary academic institutions, identify clinical predictors for surgical intervention and urinary tract infection (UTI) for upper pole pathology, and demonstrate the natural history of lower pole vesicoureteral reflux (VUR). Read More

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Prognostic factors for overall survival in malignant ureteral obstruction.

Can J Urol 2022 Jun;29(3):11162-11169

Georgetown University School of Medicine, Washington, DC, USA.

Introduction: To identify prognostic factors for overall survival (OS) in patients with malignant ureteral obstruction (MUO) from gynecologic malignancy (GM), with the goal of improving patient selection for urinary diversion.

Materials And Methods: Retrospective review of 126 patients with MUO from GM at two academic centers from 2011-2019. Factors related to OS identified by Cox regression proportional hazard model. Read More

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Randomized prospective trial of the severity of irritative symptoms after HoLEP vs ThuFLEP.

World J Urol 2022 Jun 12. Epub 2022 Jun 12.

Department of Urology, Spital Thurgau AG, Pfaffenholzstrasse 4, 8501, Frauenfeld, Switzerland.

Purpose: To compare the short-term postoperative functional outcomes and severity of irritative symptoms following holmium and thulium fiber laser enucleation (HoLEP and ThuFLEP).

Methods: This prospective randomized single-blinded study was performed in accordance with CONSORT. The inclusion criteria were IPSS > 20 or Qmax < 10 ml/s. Read More

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Management of gastro-intestinal emergencies in patients with ileal conduit ureteral diversion.

J Visc Surg 2022 Jun 8. Epub 2022 Jun 8.

Department of Digestive, Bariatric and Endocrine Surgery, Avicenne Hospital Group, AP-HP, 93000 Bobigny, France; Paris Seine-Saint-Denis University Hospitals (Paris 13), Sorbonne Paris Nord, Paris, France. Electronic address:

Radical cystectomy with urinary deviation is performed increasingly in France. Ileal conduit ureteral diversion (ICUD), described by Bricker and widely used after this type of radical resection, leads to substantial anatomic modifications that are potential danger zones during subsequent gastro-intestinal or urinary tract operations. Injury to the urinary diversion apparatus can lead to disastrous complications in these patients who are often elderly and frail. Read More

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Hidden Dangers: A Gastrointestinal Stromal Tumor Concealed Inside of a Meckel's Diverticulum.

Cureus 2022 May 7;14(5):e24810. Epub 2022 May 7.

Oncology, Bayonne Medical Center, Bayonne, USA.

Meckel's diverticulum (MD) is one of the most common congenital abnormalities of the gastrointestinal tract, affecting approximately two percent of the population. Rarely, Meckel's diverticula have been found to harbor various tumors, which go unnoticed until later in their course. The clinical presentation varies among each individual, and tumors have often metastasized or caused diverticular rupture at the time of diagnosis. Read More

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Urethral Stricture/Stenosis as a Complication of High Intensity Focused Ultrasound of the Prostate (HIFU): What is the Overall Patient Experience?

Urology 2022 Jun 6. Epub 2022 Jun 6.

Department of Urology, University of California, Irvine. Electronic address:

Objective: To analyze the location and management of urethral stricture/stenosis in patients treated with HIFU of the prostate as well as to describe patient reported satisfaction in these men.

Methods: Patients with a history of HIFU requesting consultation for stricture were identified from 2010-2020. Demographic and prior treatment data were recorded. Read More

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Prenatally diagnosed posterior urethral valves: ethical dilemmas of fetal intervention.

Urology 2022 Jun 6. Epub 2022 Jun 6.

Children's Hospital Colorado, Department of Pediatric Urology, Aurora, Colorado, USA; University of Colorado Hospital, Aurora, Colorado, USA.

Although anhydramnios due to in utero renal failure has traditionally been considered lethal, in utero interventions offer the potential for pulmonary survival. As fetal interventions become more common, questions arise about how to identify and counsel eligible candidates.  In this report we describe the presentation and management of a 17-year-old pregnant female who presented from out-of-state with severe lower urinary tract obstruction (LUTO) with associated anhydramnios, focusing on the ethical questions that this case raised. Read More

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The Use of Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Diagnostic and Prognostic Biomarker in Urinary Tract Obstruction: a Systematic Review.

Curr Urol Rep 2022 Jun 9. Epub 2022 Jun 9.

Urology Department, University Hospital Southampton, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK.

Purpose Of Review: The early recognition of urinary tract obstruction (UTO) is vital in order to prevent mortality and morbidity associated with an acute kidney injury (AKI) and progression to irreversible kidney damage. Urinary biomarkers such as neutrophil gelatinase-associated lipocalin (NGAL) have been recognised as an accurate tool in the timely diagnosis of AKI, but its role in the detection, prognosis and subsequent monitoring of a variety of obstructive uropathies has not yet been explored. We performed a systematic review of literature in accordance with Cochrane methodology from inception to August 2021. Read More

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New challenges of fetal therapy in Japan.

J Obstet Gynaecol Res 2022 Jun 8. Epub 2022 Jun 8.

Center for Maternal-Fetal, Neonatal and Reproductive Medicine, National Center for Child Health and Development, Tokyo, Japan.

Aim: To review new challenges of fetal therapy in Japan after the establishment of four existing fetal therapies as standard prenatal care with National Health Insurance coverage over the past 20 years.

Methods: Reported studies and our current research activities related to four fetal therapies newly performed in Japan were reviewed.

Results: Fetoscopic endoluminal tracheal occlusion (FETO) for congenital diaphragmatic hernia (CDH) aims to occlude the trachea using a detachable balloon to promote lung growth. Read More

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A Silicone-Covered Self-Expanding Metal Stent with Anti-migration Features for Treating Malignant Ureteral Obstruction.

Cardiovasc Intervent Radiol 2022 Jun 8. Epub 2022 Jun 8.

Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Korea.

Purpose: To evaluate the effectiveness and safety of the Urexel stent for treating malignant ureteral obstruction (MUO).

Materials And Methods: This retrospective study included 129 patients (mean age: 57.9 ± 11. Read More

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A Novel Technique with Ileal Mesentery to Reconstruct the Pelvic Peritoneum after Pelvic Dissection with End-Colostomy for Rectal Cancer.

Dis Colon Rectum 2022 May 25. Epub 2022 May 25.

Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.

Background: After abdominoperineal resection, low anterior resection, and end-colostomy for lower rectal cancer, it is necessary to reconstruct the pelvic peritoneum to avoid small bowel obstruction, perineal hernia, and radiation enteritis in patients for whom postoperative radiotherapy is planned. However, pelvic peritoneal closure is technically difficult in patients who lack enough peritoneum to cover the defect or have received neoadjuvant radiation and have a rigid pelvis.

Impact Of Innovation: The impact of this innovation is to reconstruct the pelvic peritoneum with the distal ileal mesentery laparoscopically. Read More

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Deep-learning segmentation of ultrasound images for automated calculation of the hydronephrosis area to renal parenchyma ratio.

Investig Clin Urol 2022 May 25. Epub 2022 May 25.

Department of Convergence Medicine, Asan Medical Center, Seoul, Korea.

Purpose: We investigated the feasibility of measuring the hydronephrosis area to renal parenchyma (HARP) ratio from ultrasound images using a deep-learning network.

Materials And Methods: The coronal renal ultrasound images of 195 pediatric and adolescent patients who underwent pyeloplasty to repair ureteropelvic junction obstruction were retrospectively reviewed. After excluding cases without a representative longitudinal renal image, we used a dataset of 168 images for deep-learning segmentation. Read More

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FuZhengHuaYuJiangZhuTongLuoFang Prescription Modulates Gut Microbiota and Gut-Derived Metabolites in UUO Rats.

Front Cell Infect Microbiol 2022 20;12:837205. Epub 2022 May 20.

Department of Nephrology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Background: Alteration of intestinal flora and metabolites is closely related to chronic kidney disease (CKD) across early to advanced stages. FuZhengHuaYuJiangZhuTongLuoFang prescription (FZHY) is a Chinese herb that has been proven to effectively treat CKD, but the underlying mechanism is not clear.

Methods: Rats were subjected to intragastric treatment with FZHY 7, 14, and 21 days after unilateral ureteral obstruction (UUO) surgery, and kidney tissue, colon tissue, serum, and stool samples were collected. Read More

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Twist1 downregulation of PGC-1α decreases fatty acid oxidation in tubular epithelial cells, leading to kidney fibrosis.

Theranostics 2022 1;12(8):3758-3775. Epub 2022 May 1.

Department of Nephrology, Xijing Hospital, Fourth Military Medical University, No. 127 Chang le West Road, Xi'an, Shaanxi, 710032, China.

A deficiency of fatty acid oxidation (FAO) is the metabolic hallmark in proximal tubular cells (PTCs) in renal fibrosis owing to utilization of fatty acids by PTCs as the main energy source. Lipid accumulation may promote lipotoxicity-induced pathological injury in renal tissue. However, the molecular mechanism underlying lipotoxicity and renal tubulointerstitial fibrosis (TIF) remains unclear. Read More

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Activation of the TGF-β1/Smads/α-SMA pathway is related to histological and functional changes in children with neurogenic bladder.

Sci Rep 2022 Jun 3;12(1):9285. Epub 2022 Jun 3.

Department of Pediatric Urodynamic Center, Henan Joint International Pediatric Urodynamic Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.

This research is to investigate the expression of the TGF-β1/Smads/α-SMA pathway and its effect on bladder histology and function in children with neurogenic bladder (NB). The bladder specimens from 10 children with NB and 8 children with vesicoureteral junction obstruction were collected into the NB and control groups. The expression of TGF-β1, Smad2, Smad3, Smad4, Smad6, α-SMA, fibronectin, collagen I and collagen III in bladder tissues was detected. Read More

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Giant bladder stone resulting in renal failure and concurrent bladder cancer: A case report.

Int J Surg Case Rep 2022 May 6;94:107170. Epub 2022 May 6.

Department of Urology, Cibabat Regional General Hospital, Cimahi, West Java, Indonesia.

Introduction And Importance: Giant bladder stone is a rare entity in the modern urological practice. There have been limited reports on giant bladder stone with concomitant renal failure and bladder cancer available in the literature.

Case Presentation: A 43-year-old male patient presented to the ER with chronic gross hematuria, dysuria, intermittent urination, and bilateral flank pain. Read More

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Translabial ultrasound evaluation after tension-free transobturator tape technique: Outcomes based on the tape's position.

Int J Gynaecol Obstet 2022 Jun 3. Epub 2022 Jun 3.

Gynecology and Obstetrics Unit, "Villa Sofia Cervello" Hospital, University of Palermo, Palermo, Italy.

Objective: The purpose of this study was to evaluate the feasibility and accuracy of postoperative translabial ultrasound to assess the position of the tape implanted with the tension-free transobturator tape technique.

Methods: We enrolled women with clinically and urodynamically proven type I or II stress urinary incontinence who were referred for transobturator tape treatment.

Results: A total of 50 women underwent a transobturator tape procedure and were included in the analysis. Read More

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Surgery in platinum-resistant recurrent epithelial ovarian carcinoma.

World J Clin Cases 2022 Apr;10(12):3739-3753

Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.

Background: Ovarian cancer is one of the three most common malignant tumors of the female reproductive tract and ranks first in terms of mortality among gynecological tumors. Epithelial ovarian carcinoma (EOC) is the most common ovarian malignancy, accounting for 90% of all primary ovarian tumors. The clinical value of cytoreductive surgery in patients with platinum-resistant recurrent EOC remains largely unclear. Read More

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