4,724 results match your criteria Urethritis Male

Etiological surveillance of Male Urethritis Syndrome in South Africa: 2019-2020.

Sex Transm Dis 2022 May 13. Epub 2022 May 13.

Centre for HIV & STI, National Institute for Communicable Diseases, Johannesburg, South Africa.

Background: In South Africa, male urethritis syndrome (MUS) is the most common STI syndrome in men). We determined the distribution of STI etiologies and the susceptibility profiles of Neisseria gonorrhoeae isolates from men presenting with MUS to three sentinel surveillance PHCs. Secondary objectives were to determine the seroprevalence of co-infections (HIV, syphilis, herpes simplex virus-2). Read More

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High burden of untreated syphilis, drug resistant Neisseria gonorrhoeae, and other sexually transmitted infections in men with urethral discharge syndrome in Kampala, Uganda.

BMC Infect Dis 2022 May 7;22(1):440. Epub 2022 May 7.

Division of Infectious Disease, Johns Hopkins School of Medicine, 5200 Eastern Avenue, Mason F. Lord Center Tower, Suite 381, Baltimore, MD, 21224, USA.

Objectives: Prompt diagnosis and treatment of sexually transmitted infections (STIs) are essential to combat the STI epidemic in resource-limited settings. We characterized the burden of 5 curable STIs chlamydia, gonorrhea, trichomoniasis, Mycoplasma genitalium, syphilis, and HIV infection in Ugandan men with urethritis.

Methods: Participants were recruited from a gonococcal surveillance program in Kampala, Uganda. Read More

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Primary urothelial carcinoma of the male anterior urethra; A case report.

Ann Med Surg (Lond) 2022 Apr 4;76:103561. Epub 2022 Apr 4.

Senior Urologist, Departement of Urology, FSI Hospital La Marsa, Tunisia.

Introduction: and importance: Urethral cancer is a rare condition. It represents less than 1% of all cancers and the clinical signs are not very specific and confusing, which explains the often-late diagnosis. The prognosis can be poor. Read More

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Investigating the microbial pathogens of sexually transmitted infections among heterosexual Vietnamese men with symptomatic urethritis.

Aging Male 2022 Dec;25(1):125-133

Department of Microbiology and Parasitology, Hanoi Medical University's Hospital, Hanoi, Vietnam.

Objective: To explore the microbial etiology of urethritis in Vietnamese men and the association with patients' characteristics, especially their sexual behaviors.

Methods: This study was conducted on 349 men who presented with symptomatic urethritis and evidence of STIs (determined by multiplex PCR tests) at the Department of Andrology and Sexual Medicine-Hanoi Medical University Hospital. All information regarding medical history, sexual activities, and symptoms of urethritis was documented. Read More

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December 2022

Retrospective Analysis of Ugandan Men with Urethritis Reveals Mycoplasma genitalium and Associated Macrolide Resistance.

Microbiol Spectr 2022 Apr 12;10(2):e0230421. Epub 2022 Apr 12.

Division of Infectious Diseases, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

The rising rates of antimicrobial resistance (AMR) in Mycoplasma genitalium globally and the association of this sexually transmitted infection (STI) with cervicitis, urethritis, and HIV are potentially of great public health concern. Data on the epidemiology of M. genitalium in men in sub-Saharan Africa are limited. Read More

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Gonococcal tysonitis, a rare local complication of gonorrhea: a clinical study of 15 cases.

Eur J Clin Microbiol Infect Dis 2022 May 23;41(5):787-792. Epub 2022 Mar 23.

Department of Clinical Laboratory, First People's Hospital of Changshu City, Changshu Hospital Affiliated To Soochow University, Changshu, 215500, Jiangsu Province, People's Republic of China.

To investigate the incidence, clinical manifestations, and treatments of gonococcal tysonitis in men. We enrolled men with gonococcal tysonitis and men with gonococcal urethritis from January 2000 to December 2020. Demographic data, interval from non-marital sexual contact to the onset of symptoms of gonococcal tysonitis, occurrence sites, and manifestations were recorded for all patients. Read More

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Clinical Importance of Superior Sensitivity of the Aptima TMA-Based Assays for Mycoplasma genitalium Detection.

J Clin Microbiol 2022 04 23;60(4):e0236921. Epub 2022 Mar 23.

Infection Preparedness, Research Unit for Reproductive Tract Microbiology, Statens Serum Institutgrid.6203.7, Copenhagen, Denmark.

Mycoplasma genitalium (MG) is a common cause of nongonococcal cervicitis and urethritis. We investigated the demographic and clinical characteristics of patients tested in Denmark with the Conformité Européenne (CE)/ diagnostics (IVD) Aptima Mycoplasma genitalium assay (CE/IVD AMG; Hologic) and examined the clinical significance of the higher sensitivity of the TMA-based MG assays. From March to June 2016, urogenital and extragenital specimens from consecutive attendees at a sexually transmitted infection clinic in Copenhagen, Denmark were tested with the CE/IVD AMG assay (TMA-based), the research-use-only MG Alt TMA-1 assay (Hologic), a laboratory-developed TaqMan B quantitative real-time PCR (qPCR), and the Aptima Combo 2 (CT/NG; Hologic). Read More

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Endogenous endophthalmitis caused by Staphylococcus capitis.

Am J Ophthalmol Case Rep 2022 Mar 10;25:101415. Epub 2022 Feb 10.

Department of Ophthalmology, Bernice and Harvey Jones Eye Institute, University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Purpose: To report a rare case of endogenous endophthalmitis caused by Staphylococcus capitis.

Observation: A 34-year-old male patient with a history of gonococcal urethritis and arthritis presented with right endogenous endophthalmitis. Vitreous biopsy culture confirmed Staphylococcus capitis involvement. Read More

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2021 European guideline on the management of Mycoplasma genitalium infections.

J Eur Acad Dermatol Venereol 2022 May 19;36(5):641-650. Epub 2022 Feb 19.

WHO Collaborating Centre for Gonorrhoea and other STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University Hospital, Örebro University, Örebro, Sweden.

Mycoplasma genitalium infection contributes to 10-35% of non-chlamydial non-gonococcal urethritis in men. In women, M. genitalium is associated with cervicitis and pelvic inflammatory disease (PID) in 10-25%. Read More

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Characterization of urethritis-associated Neisseria meningitidis isolated from men who have sex with women in China.

J Infect 2022 05 22;84(5):e87-e88. Epub 2022 Jan 22.

Department of Pharmaceutical Microbiology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China. Electronic address:

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Evaluating the utility of the A.F. Genital System test for pathogen diagnosis in acute male urethritis.

Andrologia 2022 May 22;54(4):e14377. Epub 2022 Jan 22.

Faculty of Health Science, Avrasya University, Trabzon, Turkey.

This study evaluated the effectiveness of the A.F. Genital System (Liofilchem , Italy) in detecting pathogens compared with multiplex real-time polymerase chain reaction (PCR) in men with acute urethritis. Read More

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Carbon ion radiotherapy with complete tumor regression for primary malignant melanoma of female urethra orifice: a case report.

J Int Med Res 2022 Jan;50(1):3000605211072795

Heavy Ion Center of Wuwei Cancer Hospital, Wuwei, Gansu, China.

Primary malignant melanoma of the female urethra (PMMFU) is extremely rare, accounting for 0.2% of all melanomas, and fewer than 200 cases have been reported worldwide. Because of the small number of clinical cases and unclear biological characteristics, there is no uniform and standard treatment protocol. Read More

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January 2022

Unusual presentation of a periurethral abscess following infection with .

BMJ Case Rep 2022 Jan 4;15(1). Epub 2022 Jan 4.

Urology, Mid Yorkshire Hospitals NHS Trust, Wakefield, UK

We describe an unusual case of a male patient presenting with penile and testicular swelling following an unprotected and traumatic sexual encounter. It was suspected that an isolated penile injury occurred during intercourse; however, ultrasound imaging identified an intact tunical layer and right-sided epididymo-orchitis. Following screening for sexually transmitted infections (STIs), he was discharged with antibiotics and advice to attend the Sexual Health Centre for contact tracing. Read More

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January 2022

Emergence of antibiotic-resistant Mycoplasma genitalium as the cause of non-gonococcal urethritis in male patients at a sexually transmitted infection clinic.

Int J Antimicrob Agents 2022 Feb 28;59(2):106510. Epub 2021 Dec 28.

Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address:

Mycoplasma genitalium is the cause of an emerging sexually transmitted infection (STI) with high propensity for development of antimicrobial resistance. In a prevalence study conducted at the public STI service in Hong Kong, the first void urine samples of 38 (8%) of 493 male patients with non-gonococcal urethritis (NGU) tested positive for M. genitalium using reverse transcription polymerase chain reaction. Read More

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February 2022

[Urethral microbiota in healthy men and patients with urethritis].

Urologiia 2021 Dec(6):136-140

Peoples Friendship University of Russia, Department of professional Development of the Medical Men, Endoscopic Urology clinic, Moscow, Russia.

Non-gonococcal urethritis (NGU) is a common disease in men. The main cause of NGU is sexually transmitted infections, which can cause various complications, including reproductive ones. Chlamydia trachomatis and Mycoplasma genitalium are the most common causes of NGU, but no known viral or bacterial pathogens are detected in 28-50% of cases. Read More

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December 2021

[Perineal and penile urethrostomy: surgical outcome and risk assessment of complications].

Urologiia 2021 Dec(6):5-13

Rostov State Medical University, Rostov-on-Don, Russia.

Introduction: Urethral repair in the complex urethral strictures (US) is associated with a high risk of failure. In some cases, urethrostomy is justified when choosing a method of treatment for this category of patients.

Purpose Of The Study: To assess the results of perineal and penile urethrostomy and identify factors associated with the development of early surgical complications and urethrostomy stenosis (USs). Read More

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December 2021

Macrolide-Resistant Mycoplasma genitalium Impairs Clinical Improvement of Male Urethritis After Empirical Treatment.

Sex Transm Dis 2022 05;49(5):360-367

From the Department of Infectious Diseases, Public Health Service of Amsterdam.

Background: Mycoplasma genitalium (MG) is associated with urethritis in men and could play a role in clinical outcome. We examined clinical improvement of symptoms in men receiving empirical treatment for urethritis and correlated the outcome with Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), MG, and MG macrolide resistance-associated mutations (MRAM) status.

Methods: At the sexually transmitted infection clinic in Amsterdam, the Netherlands, empirical treatment for gonococcal urethritis is 1 g ceftriaxone and for nongonococcal urethritis 1 g azithromycin. Read More

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Provokes Seminal Inflammation among Infertile Males.

Int J Mol Sci 2021 Dec 15;22(24). Epub 2021 Dec 15.

Andrology Centre, Tartu University Hospital, Ludvig Puusepa 8 Street, 50406 Tartu, Estonia.

The impact of sexually transmitted infections (STI) on male fertility is controversial. Aims: To investigate the prevalence of urethritis-associated STIs (chlamydia, gonorrhoeae, , trichomoniasis) among infertile males; to analyze the effect of STIs on semen parameters and blood PSA. Case-control study. Read More

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December 2021

Epidemiological, clinical and laboratory differences between male urethral infections due to Haemophilus spp. and those due to Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium and Ureaplasma urealyticum: A descriptive study.

Arch Ital Urol Androl 2021 Dec 21;93(4):468-474. Epub 2021 Dec 21.

Sexually Transmitted Infection Department, Andrology Service, Fundació Puigvert, Universitat Autònoma de Barcelona, Barcelona.

Objective: To describe the epidemiological, clinical and laboratory characteristics of male patients diagnosed with Haemophilus spp. urethral infection and to compare them with the characteristics of male patients diagnosed with N. gonorrhoeae, C. Read More

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December 2021

Detection of Neisseria gonorrhoeae or Chlamydia trachomatis from oral wash specimens using the Abbott RealTime CT/NG assay and the Cobas 4800 CT/NG assay: A prospective study.

J Infect Chemother 2022 Apr 17;28(4):480-485. Epub 2021 Dec 17.

Department of Urology, University of Occupational and Environmental Health, Kitakyushu, Japan.

Introduction: Isolating oropharyngeal Neisseria gonorrhoeae (NG) and Chlamydia trachomatis (CT) from oral wash specimens (OWSs) is uncommon. Therefore, we evaluated the performance of the Abbott RealTime CT/NG assay and the Cobas 4800 CT/NG assay in detecting NG and CT in OWSs.

Methods: This multicenter prospective study included 457 patients from 14 medical facilities suspected of having untreated male urethritis or female cervicitis from November 2014 to December 2015. Read More

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Mycoplasma genitalium and sexually transmitted infections: evidences and figures in a tertiary hospital.

Rev Esp Quimioter 2022 Feb 17;35(1):76-79. Epub 2021 Dec 17.

Juan M. García-Lechuz Moya, Servicio de Microbiología. Paseo Isabel La Católica 1-4, Hospital Universitario Miguel Servet, Zaragoza 50006. Spain.

Objective: Mycoplasma genitalium is an emerging cause of sexually transmitted infections (STIs) and has been implicated in non-gonococcal urethritis in men and cervicitis in woman. The aim of this study is determinate the incidence and pathogenicity of M. genitalium within the diagnosis of STIs detected from clinical samples in a third level hospital. Read More

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February 2022

Incidence and risk factors of gonococcal urethritis reinfection among Thai male patients in a multicenter, retrospective cohort study.

Sci Rep 2021 11 26;11(1):22992. Epub 2021 Nov 26.

Division of Dermatology, Department of Medicine, Phramongkutklao Hospital, Bangkok, 10400, Thailand.

Gonococcal urethritis (GU) is the second most common sexually transmitted infection (STI). Epidemiologic studies of the situation of GU reinfection and its related risk factors among patients with a history of GU in Thailand remain somewhat limited. A hospital-based retrospective cohort study was conducted between January 1, 2010 and December 31, 2020 to determine the incidence and risk factors of GU reinfection among male patients visiting in Royal Thai Army (RTA) Hospitals. Read More

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November 2021

Evaluation of Urethrotropic-Clade Meningococcal Infection by Urine Metagenomic Shotgun Sequencing.

J Clin Microbiol 2022 02 24;60(2):e0173221. Epub 2021 Nov 24.

Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Preventiongrid.416738.f, Atlanta, Georgia, USA.

Urethral infections caused by an emerging nongroupable (NG) urethrotropic clade of Neisseria meningitidis were first reported in the United States in 2015 (the "U.S. NmNG urethritis clade"). Read More

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February 2022

Molecular mechanisms of macrolide and fluoroquinolone resistance among Korean isolates of over a period of five years 2014-2019.

J Med Microbiol 2021 Nov;70(11)

Department of Urology, Dankook University College of Medicine, Cheonan, Republic of Korea.

Antimicrobial resistance in has become a global issue, and certain groups have a higher probability of acquiring resistant strains. Little is known about the genetic diversity and characteristics of the antimicrobial resistance-determining sites (ARDSs) of in the Korean population. Therefore, we examined the genetic diversity of the ARDSs of positive urogenital samples obtained from Korean females (G1) and males (G2) visiting primary care clinics and DNA samples from referred males (G3) with persistent urethritis. Read More

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November 2021

Aptima Assay for Detection of Mycoplasma genitalium Infection.

Am Fam Physician 2021 11;104(5):517-518

Penn State Health Milton S. Hershey Medical Center, Hershey, PA, USA.

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November 2021

Gentamicin Susceptibility in Neisseria gonorrhoeae and Treatment Outcomes for Urogenital Gonorrhea After 25 Years of Sustained Gentamicin Use in Malawi.

Sex Transm Dis 2022 04;49(4):251-256

Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Background: Gentamicin has been used for the treatment of gonorrhea in Malawi since 1993. However, declining clinical cure rates have been suspected. We evaluated current Neisseria gonorrhoeae susceptibility to gentamicin in vitro and clinically. Read More

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[Mycoplasma genitalium probably as common in Sweden as Chlamydia trachomatis].

Eva Björnelius

Lakartidningen 2021 11 1;118. Epub 2021 Nov 1.

med dr, överläkare, hudkliniken, Karolinska universitetssjukhuset Huddinge, Stockholm.

Mycoplasma genitalium is a common sexually transmitted infection, probably as common in Swedish STI clinics as Chlamydia trachomatis. M. genitalium may cause urethritis in men and and urethritis, cervicitis, pelvic inflammatory disease (PID) and infertility in women. Read More

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November 2021

Gonococcal bacterial load in PrEP users with Mycoplasma genitalium coinfection.

Int J STD AIDS 2022 02 2;33(2):129-135. Epub 2021 Nov 2.

Department of Clinical Sciences, 567788Institute of Tropical Medicine Antwerp, Antwerp, Belgium.

Objectives: Gonococcal infections with a higher bacterial load may pose a higher risk of transmission. We assessed the association between gonococcal bacterial load and coinfection with .

Methods: From September 2015 until May 2018, 200 men and transgender women who have sex with men participated in an HIV pre-exposure prophylaxis (PrEP) demonstration trial in Antwerp, Belgium. Read More

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February 2022

Characterization of sexually transmitted infections, their pharmacological treatment, and recurrence in a Colombian population.

Biomedica 2021 10 15;41(Sp. 2):130-139. Epub 2021 Oct 15.

Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A, Pereira, Colombia.

Introduction: Sexually transmitted infections are a public health problem worldwide. Their inadequate antimicrobial management has been associated with a higher risk of recurrence.

Objective: To characterize the main sexually transmitted infections, the adherence to clinical practice guidelines, and the factors associated with recurrence in Colombia. Read More

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October 2021

Evaluation of Clinical, Gram Stain, and Microbiological Cure Outcomes in Men Receiving Azithromycin for Acute Nongonococcal Urethritis: Discordant Cures Are Associated With Mycoplasma genitalium Infection.

Sex Transm Dis 2022 01;49(1):67-75

From the Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN.

Background: In men with nongonococcal urethritis (NGU), clinicians and patients rely on clinical cure to guide the need for additional testing/treatment and when to resume sex, respectively; however, discordant clinical and microbiological cure outcomes do occur. How accurately clinical cure reflects microbiological cure in specific sexually transmitted infections (STIs) is unclear.

Methods: Men with NGU were tested for Neisseria gonorrhoeae, Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), Trichomonas vaginalis, urethrotropic Neisseria meningitidis ST-11 clade strains, and Ureaplasma urealyticum (UU). Read More

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January 2022