4,525 results match your criteria Urethritis Male


Mycoplasma genitalium in symptomatic male urethritis: macrolide use is associated with increased resistance.

Clin Infect Dis 2019 Apr 11. Epub 2019 Apr 11.

Departments of Medicine, Division of Infectious Diseases and Immunology University of Massachusetts Medical School, Worcester, MA, United States.

Background: Mycoplasma genitalium (Mg) causes symptomatic urethritis in men, and can infect alone or together with other STI agents.

Methods: The prevalence of Mg and other STIs were determined in 1816 men with symptomatic urethritis. Resistance of Mg to macrolides and fluoroquinolones was determined by sequencing; the impact of recent antimicrobial usage on the distribution of Mg single or mixed infections was determined. Read More

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http://dx.doi.org/10.1093/cid/ciz294DOI Listing
April 2019
8.886 Impact Factor

Detection of ureaplasmas and bacterial vaginosis associated bacteria and their association with non-gonococcal urethritis in men.

PLoS One 2019 4;14(4):e0214425. Epub 2019 Apr 4.

Research Unit for Reproductive Microbiology, Statens Serum Institut, Copenhagen S, Denmark.

No aetiology is found in up to 40% of men with symptomatic urethritis. Male partners of women with bacterial vaginosis (BV) may be at higher risk of non-gonococcal urethritis (NGU). The aim of this study was to examine the role of BV associated bacteria in first-void urine (FVU) in 97 asymptomatic men without urethritis (controls) and 44 men (cases) with NGU including 20 men with idiopathic urethritis (IU) attending a Swedish STD-clinic between January and October 2010. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214425PLOS
April 2019
2 Reads

Infectious human adenoviruses are shed in urine even after disappearance of urethral symptoms.

PLoS One 2019 6;14(3):e0212434. Epub 2019 Mar 6.

Department of Urology, Kizawa Memorial Hospital, Minokamo, Gifu, Japan.

Background: Urethritis is a common sexually transmitted disease, and human adenoviruses (HAdVs) have been found to be associated with nonchlamydial nongonococcal urethritis. However, the level and viability of HAdV in the urine of patients with urethritis remain unclear.

Methods: Male patients with urethritis and an asymptomatic group were screened using their First-void urine (FVU) for urethritis-related pathogens to identify those with HAdV DNA. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212434PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402629PMC

Specific characteristics of urethral strictures in a developing country (Brazil).

World J Urol 2019 Apr 27;37(4):661-666. Epub 2019 Feb 27.

Department of Surgery, Division of Urology, Sao Paulo Federal University (UNIFESP), São Paulo, Brazil.

Purpose: Evaluate the main etiologies and clinical characteristics of male urethral stricture disease (USD) in Brazil.

Methods: This multicentric study was performed using retrospective data collected from six Brazilian referral centers of urethral reconstruction. The database comprised data from 899 patients with USD who had undergone surgical treatment from 2008 to 2018. Read More

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http://dx.doi.org/10.1007/s00345-019-02696-9DOI Listing
April 2019
2 Reads

Roles of Species in Idiopathic Chronic Prostatitis: A Case-Control Study.

World J Mens Health 2019 Feb 12. Epub 2019 Feb 12.

Department of Urology, Dankook University College of Medicine, Cheonan, Korea.

Purpose: Because of the inconsistent symptoms associated with infections, their clinical significances in genitourinary tracts are under debate. Therefore, we evaluated the presence of (UU) and (UP) in urine samples and examined their associations with chronic prostatitis (CP) through a case and control study.

Materials And Methods: We included 696 nonchlamydial nongonococcal (NCNG) urine samples from men; 350 were categorized into non-inflammatory CP, 88 in inflammatory CP, and 258 in non-CP group. Read More

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http://dx.doi.org/10.5534/wjmh.180081DOI Listing
February 2019

Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report.

Int J STD AIDS 2019 Apr 4;30(5):519-521. Epub 2019 Feb 4.

1 Department of Medical Microbiology, University of Pretoria, Pretoria, South Africa.

We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. Read More

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http://dx.doi.org/10.1177/0956462418820745DOI Listing
April 2019
2 Reads

Urethral cavernous hemangioma: a highly misdiagnosed disease (a case report of two patients and literature review).

BMC Urol 2019 Jan 31;19(1):13. Epub 2019 Jan 31.

Department of Urology, First Affiliated Hospital of Sun Yat-sen university, Guangzhou, 510080, China.

Background: Diagnosis of urethral cavernous hemangioma (UCH) is very rare. It can be easy to misdiagnose and mistreat due to its atypical clinical manifestations and a lack of relevant knowledge. The study is to explore the diagnosis, differential diagnosis, and treatment of UCH. Read More

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http://dx.doi.org/10.1186/s12894-019-0441-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357368PMC
January 2019
2 Reads

Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women.

Cochrane Database Syst Rev 2019 Jan 25;1:CD010871. Epub 2019 Jan 25.

Clinical Research Institute, Faculty of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.

Background: The genital infection caused by Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) globally. The infection is mainly asymptomatic in women, thus it can produce infertility and chronic pelvic pain. In men infection is mainly symptomatic, but can evolve to prostatitis. Read More

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http://dx.doi.org/10.1002/14651858.CD010871.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353232PMC
January 2019
5 Reads

Evaluation of Susceptibilities to Carbapenems and Faropenem Against Cephalosporin-Resistant Neisseria gonorrhoeae Clinical Isolates with penA Mosaic Alleles.

Microb Drug Resist 2019 Apr 24;25(3):427-433. Epub 2019 Jan 24.

3 Department of Microbiology, Sapporo Medical University School of Medicine, Sapporo, Japan.

Neisseria gonorrhoeae is a principal pathogen for sexually transmitted infections, especially for male urethritis. Currently, the prevalence of multidrug resistance is increasing. Carbapenems are broad-spectrum antimicrobials that are widely used in the clinical setting, especially for multidrug-resistant Gram-negative bacteria. Read More

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http://dx.doi.org/10.1089/mdr.2018.0263DOI Listing
April 2019
1 Read

Chlamydia trachomatis screening in urine among asymptomatic men attending an STI clinic in Paris: a cross-sectional study.

BMC Infect Dis 2019 Jan 8;19(1):31. Epub 2019 Jan 8.

Department of Infectious Diseases, University Hospital Saint-Antoine, APHP, 75012, Paris, France.

Background: The incidence of Chlamydia trachomatis (Ct) urethritis has been increasing for the past 10 years. There is little data regarding the screening of Ct infection in asymptomatic men in France, despite the national recommendation to screen at-risk asymptomatic men under 30 attending Sexually Transmitted Infections (STI) clinics. Recent data from the French surveillance network Rénachla show indeed that systematic screening is still focused on women. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3595-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325815PMC
January 2019
12 Reads

Clinical, histopathologic, cystoscopic, and fluorescence in situ hybridization analysis of proliferative urethritis in 22 dogs.

J Vet Intern Med 2019 Jan 5;33(1):184-191. Epub 2018 Dec 5.

Department of Medicine and Epidemiology, Veterinary Medical Teaching Hospital, University of California-Davis School of Veterinary Medicine, California.

Background: Proliferative urethritis (PU) is a lower urinary tract disease of dogs characterized by frond-like lesions in the urethra. The etiology of PU is unknown, although an association with bacterial cystitis is reported.

Objectives: Deep-seated bacterial cystitis is associated with PU, particularly in dogs with neutrophilic or granulomatous inflammation. Read More

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http://dx.doi.org/10.1111/jvim.15349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335574PMC
January 2019
4 Reads

The demographic and clinical profiles of women presenting with vaginal discharge syndrome at primary care facilities in South Africa: Associations with age and implications for management.

S Afr Med J 2018 Oct 2;108(10):876-880. Epub 2018 Oct 2.

Centre for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Current South African guidelines for the management of vaginal discharge syndrome (VDS) do not recommend treatment for sexually transmitted infection (STI) pathogens for women aged ≥35 years whose partners do not have male urethritis syndrome. The guideline assumes that older women are unlikely to have an STI and that their partners do not have asymptomatic infections.

Objectives: To describe the demographic, behavioural and clinical characteristics of women with VDS, comparing older women (≥35 years) with younger women, and to determine the performance of age alone as a criterion for predicting the presence of STI. Read More

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http://dx.doi.org/10.7196/SAMJ.2018.v108i10.13027DOI Listing
October 2018
4 Reads

The first year of the global Enhanced Gonococcal Antimicrobial Surveillance Programme (EGASP) in Bangkok, Thailand, 2015-2016.

PLoS One 2018 9;13(11):e0206419. Epub 2018 Nov 9.

Thailand Ministry of Public Health-U.S. Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand.

Antimicrobial-resistant Neisseria gonorrhoeae (NG) infection is a global public health threat, and there is a critical need to monitor patterns of resistance and risk factors. In collaboration with the World Health Organization (WHO), the U.S. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206419PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226150PMC
April 2019
25 Reads

Chlamydia trachomatis asymptomatic urethritis recurrence among males living with HIV-1.

Rev Inst Med Trop Sao Paulo 2018 Oct 25;60:e65. Epub 2018 Oct 25.

Universidade Federal do Estado do Rio de Janeiro, Serviço de Clínica Médica, 10ᵃ Enfermaria, Rio de Janeiro, Rio de Janeiro, Brazil.

A prevalence of 3.47% of asymptomatic Chlamydia trachomatis urethritis has been previously reported among males living with HIV infection in Brazil. This study aims to assess the recurrence of C. Read More

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http://dx.doi.org/10.1590/S1678-9946201860065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201765PMC
October 2018
3 Reads

Adult gonorrhea, chlamydia and syphilis prevalence, incidence, treatment and syndromic case reporting in South Africa: Estimates using the Spectrum-STI model, 1990-2017.

PLoS One 2018 15;13(10):e0205863. Epub 2018 Oct 15.

Avenir Health, Geneva, Switzerland.

Objectives: To estimate trends in prevalence and incidence of syphilis, gonorrhea and chlamydia in adult men and women in South Africa.

Methods: The Spectrum-STI tool estimated trends in prevalence and incidence of active syphilis, gonorrhea and chlamydia, fitting South African prevalence data. Results were used, alongside programmatic surveillance data, to estimate trends in incident gonorrhea cases resistant to first-line treatment, and the reporting gap of symptomatic male gonorrhea and chlamydia cases treated but not reported as cases of urethritis syndrome. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205863PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188893PMC
April 2019
4 Reads

Hyperthyroidism is not a significant risk of benign prostatic hyperplasia: A nationwide population-based study.

Medicine (Baltimore) 2018 Sep;97(39):e12459

Departments of Anesthesiology, Medical Research, Obstetrics and Gynecology, Management Office for Health Data, and Urology, China Medical University Hospital.

Benign prostatic hyperplasia (BPH) is a common disorder in the aging male population. Despite evidence that thyroid status impacts the prostate, the objective of this study was to examine whether patients with hyperthyroidism were at a greater risk for BPH.This study is a retrospective nationwide population-based cohort study of the Chinese population. Read More

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http://dx.doi.org/10.1097/MD.0000000000012459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181623PMC
September 2018
6 Reads

Microscopy of Gram-stained urethral smear in the diagnosis of urethritis: Which threshold value should be selected?

Andrologia 2018 Dec 20;50(10):e13143. Epub 2018 Sep 20.

Department of Urology, Gözde Hospital, Malatya, Turkey.

The aim of this study was to investigate the sensitivity of GSS in the diagnosis of urethritis in patients who present to the outpatient clinic with symptoms of urethritis. Sixty-three male patients who presented to our outpatient clinic with symptoms of urethritis between January and March 2018 were evaluated. Urethral smear samples obtained from patients were evaluated both by GSS examination and by Real-time Multiplex Polymerase Chain Reaction (rt-MPCR) assay. Read More

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http://dx.doi.org/10.1111/and.13143DOI Listing
December 2018
14 Reads

Primary Syphilis in the Male Urethra - A Case Report.

Clin Infect Dis 2018 Sep 10. Epub 2018 Sep 10.

Department of Epidemiology, University of Washington, Seattle, Washington, United States.

A man with nongonococcal urethritis had negative syphilis serology. We documented urethral Treponema pallidum infection using broad-range bacterial polymerase-chain-reaction and sequencing, targeted polymerase-chain-reaction, and immunofluorescence microscopy. The patient subsequently seroconverted for syphilis; symptoms resolved with penicillin. Read More

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http://dx.doi.org/10.1093/cid/ciy771DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424071PMC
September 2018
4 Reads

Microscopic examination of Gram-stained smears for anogenital gonorrhoea in men who have sex with men is cost-effective: evidence from a modelling study.

Sex Transm Infect 2019 02 8;95(1):13-20. Epub 2018 Sep 8.

Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Objective: To assess the cost-effectiveness of three testing strategies with or without light microscopic Gram-stained smear (GSS) evaluation for the detection of anogenital gonorrhoea among men who have sex with men (MSM) at the Amsterdam STI clinic using a healthcare payer perspective.

Methods: Three testing strategies for MSM were compared: (1) GSS in symptomatic MSM only (currently practised strategy), (2) no GSS and (3) GSS in symptomatic and asymptomatic MSM. The three testing protocols include testing with nucleic acid amplification test to verify the GSS results in (1) and (3), or as the only test in (2). Read More

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http://dx.doi.org/10.1136/sextrans-2018-053578DOI Listing
February 2019
19 Reads

Cross-sectional study of urethral exposures at last sexual episode associated with non-gonococcal urethritis among STD clinic patients.

Sex Transm Infect 2019 May 4;95(3):212-218. Epub 2018 Sep 4.

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

Objective: Although (CT) and (MG) are major causes of non-gonococcal urethritis (NGU), up to 50% of cases are of unknown aetiology. We sought to identify urethral exposures at last sexual episode associated with NGU and non-CT/non-MG NGU to identify anatomical sites from which aetiologically relevant micro-organisms may be acquired.

Methods: We enrolled STD clinic patients with and without NGU assigned male sex at birth and age ≥16 into a cross-sectional study. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053634DOI Listing
May 2019
20 Reads

[Mycoplasma genitalium and male urogenital diseases: An update].

Zhonghua Nan Ke Xue 2018 Jul;24(7):645-650

Department of Andrology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.

Mycoplasma genitalium (MG) was first isolated by Tully from the urinary tract of the male patient with non-gonococcal urethritis (NGU) in 1981. MG is extremely difficult to be cultured and was rarely studied until the development and application of molecular biology technology. The research on MG in China is still in the primary stage. Read More

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July 2018
15 Reads

Acute kidney injury caused by systemic Neisseria gonorrhoeae infection after successful kidney transplantation.

Transpl Infect Dis 2018 Dec 21;20(6):e12987. Epub 2018 Sep 21.

Department of Urology, Sapporo City General Hospital, Sapporo, Japan.

Neisseria gonorrhoeae is one of the microbes that can causes male urethritis. This microbe is most likely to be transmitted via sexual intercourse. In men, the representative infection sites are the urethra, and oral mucosa but gonococcemia is rere. Read More

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http://doi.wiley.com/10.1111/tid.12987
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http://dx.doi.org/10.1111/tid.12987DOI Listing
December 2018
11 Reads

Is urethral microscopy useful in symptomatic male patients without urethral discharge?

Int J STD AIDS 2019 Jan 31;30(1):79-81. Epub 2018 Aug 31.

Sexual Health Department, the Great Western Hospital, Swindon, UK.

National guidelines recommend that male patients presenting with symptoms of urethritis or epididymo-orchitis undergo a urethral swab for microscopy. However, this is resource intensive. The aim of this audit was to determine the proportion of symptomatic patients without urethral discharge who have positive findings on urethral swab microscopy and explore associations between presenting symptoms and microscopy findings. Read More

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http://dx.doi.org/10.1177/0956462418793511DOI Listing
January 2019
1 Read

A microbial game of whack-a-mole: clinical case series of the urethral uncloaking phenomenon caused by Corynebacterium glucuronolyticum in men treated for Chlamydia trachomatis urethritis.

Infection 2019 Feb 30;47(1):121-124. Epub 2018 Aug 30.

Clinical Microbiology and Parasitology Unit, Polyclinic "Dr. Zora Profozić", Bosutska 19, Zagreb, 10 000, Croatia.

Corynebacterium glucuronolyticum is a rare and neglected, but increasingly recognized bacterial agent of infectious urethritis and other genitourinary syndromes in men. This is the first description of its proclivity to resurface as a cause of sustained urethritis in male patients previously treated for Chlamydia trachomatis, which represents a phenomenon that has to be differentiated from a simple post-treatment overgrowth of a colonizing agent. Read More

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http://link.springer.com/10.1007/s15010-018-1211-8
Publisher Site
http://dx.doi.org/10.1007/s15010-018-1211-8DOI Listing
February 2019
8 Reads

[Etiological factors for calculus-associated seminal vesiculitis: Analysis of calculus composition in 6 cases].

Zhonghua Nan Ke Xue 2018 Feb;24(2):128-132

Center of Urology and Nephrology, Ningbo First Hospital, Zhejiang University, Ningbo, Zhejiang 315010, China.

Objective: To explore the etiological factors for calculus-associated seminal vesiculitis by analyzing the composition of seminal vesicle calculus samples.

Methods: This retrospective study included 6 cases of recurrent hematospermia diagnosed with seminal vesicle calculus by non-contrast pelvic CT. The patients were aged 28 to 69 years, with persistent or recurrent hematospermia for 3 months to 6 years, and 5 of them with a history of acute urethritis. Read More

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February 2018
5 Reads

Mycoplasma genitalium in the Far North Queensland backpacker population: An observational study of prevalence and azithromycin resistance.

PLoS One 2018 28;13(8):e0202428. Epub 2018 Aug 28.

James Cook University Clinical School, Cairns Hospital, Cairns, Queensland, Australia.

Background: Mycoplasma genitalium is a sexually transmitted infection (STI), and a common cause of non-gonococcal urethritis (NGU). There is concern regarding the rise in prevalence of M. genitalium and rates of resistance to macrolide antibiotics. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202428PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112622PMC
February 2019
2 Reads

Antibiotic resistance in Neisseria gonorrhoea and treatment outcomes of gonococcal urethritis suspected patients in two large hospitals in Bhutan, 2015.

PLoS One 2018 1;13(8):e0201721. Epub 2018 Aug 1.

Phuentsholing General Hospital, Phuentsholing, Bhutan.

Introduction: Gonorrhea is a major sexually transmitted infection (STI) globally with increasing trends. Despite limited data, gonorrhea remains an important public health problem in Bhutan.

Methods: A descriptive study was carried out in two Bhutanese hospitals; Jigme Dorji Wangchuck National Referral Hospital and Phuentsholing General Hospital in 2015. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201721PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6070275PMC
February 2019
3 Reads

The bacterial microbiota in first-void urine from men with and without idiopathic urethritis.

PLoS One 2018 27;13(7):e0201380. Epub 2018 Jul 27.

Department of Bacteriology, Parasitology and Mycology, Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Background: Non-gonococcal urethritis (NGU) is a common syndrome in men. NGU may have several causes, but many cases are caused by sexually transmitted infections that may also cause complications in their female partners. Chlamydia trachomatis and Mycoplasma genitalium are the most common causes of NGU, but in up to 35% of the cases, none of the known viral or bacterial causes are found. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201380PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063444PMC
January 2019
6 Reads

Trends in Antimicrobial Resistance over a Ten-Year Surveillance Period, Johannesburg, South Africa, 2008⁻2017.

Antibiotics (Basel) 2018 Jul 12;7(3). Epub 2018 Jul 12.

Centre for HIV & Sexually Transmitted Infections, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.

Background: In South Africa, sexually transmitted infections (STIs) are managed through a syndromic approach at primary healthcare centres (PHCs). is the predominant cause of male urethritis syndrome. We describe antimicrobial resistance patterns and trends in during a ten-year surveillance period at a large PHC in Johannesburg. Read More

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http://dx.doi.org/10.3390/antibiotics7030058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165174PMC
July 2018
1 Read

Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women.

mSphere 2018 08 27;3(3). Epub 2018 Jun 27.

Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, USA

is a bacterial pathogen responsible for the sexually transmitted infection gonorrhea. Emergence of antimicrobial resistance (AMR) of worldwide has resulted in limited therapeutic choices for this infection. Men who seek treatment often have symptomatic urethritis; in contrast, gonococcal cervicitis in women is usually minimally symptomatic, but may progress to pelvic inflammatory disease. Read More

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http://dx.doi.org/10.1128/mSphereDirect.00312-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021601PMC
August 2018
25 Reads
1 Citation

Should we be testing for urogenital Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum in men and women? - a position statement from the European STI Guidelines Editorial Board.

J Eur Acad Dermatol Venereol 2018 Nov 6;32(11):1845-1851. Epub 2018 Jul 6.

Department of Laboratory Medicine, Microbiology, World Health Organization Collaborating Centre for Gonorrhoea and Other STIs, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

At present, we have no evidence that we are doing more good than harm detecting and subsequently treating Mycoplasma hominis, Ureaplasma parvum and Ureaplasma urealyticum colonizations/infections. Consequently, routine testing and treatment of asymptomatic or symptomatic men and women for M. hominis, U. Read More

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http://dx.doi.org/10.1111/jdv.15146DOI Listing
November 2018
29 Reads

Principles and practice of high-dose rate penile brachytherapy: Planning and delivery techniques.

Pract Radiat Oncol 2018 Nov - Dec;8(6):e386-e391. Epub 2018 Jun 8.

Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio.

Purpose: To allow for organ preservation, high-dose rate (HDR) brachytherapy may be used in the treatment of localized penile cancer. Penile cancer is a rare malignancy that accounts for <1% of cancers in men in the United States. The standard treatment for localized disease is partial amputation of the penis. Read More

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http://dx.doi.org/10.1016/j.prro.2018.06.002DOI Listing
January 2019
29 Reads

Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.

PLoS One 2018 8;13(6):e0198355. Epub 2018 Jun 8.

Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Macrolide or fluoroquinolone-resistant Mycoplasma genitalium is spreading worldwide. We aimed to determine the influence of single nucleotide polymorphisms (SNPs) in the quinolone resistance determining regions (QRDR) of parC and gyrA in cultured M. genitalium strains. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198355PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993279PMC
December 2018
26 Reads

Risk factors for human papillomavirus detection in urine samples of heterosexual men visiting urological clinics in Japan.

J Infect Chemother 2018 Sep 11;24(9):713-717. Epub 2018 May 11.

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan.

Objective: The present study aimed to investigate human papillomavirus (HPV) prevalence and identify risk factors for HPV detection in urine samples among heterosexual men attending urological clinics.

Materials And Methods: Spot urine samples including initial stream were collected from 845 participants, and the cell pellets were preserved into liquid-based cytological solution. After DNA extraction from each sample, HPV-DNA amplification and genotyping were performed using Luminex multiplex polymerase chain reaction. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.04.011DOI Listing
September 2018
1 Read

[Ningmitai Capsule for the treatment of andrological diseases: Advances in studies].

Zhonghua Nan Ke Xue 2017 Oct;23(10):933-937

Department of Andrology, Jinling Hospital Affiliated to Southern Medical University / Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China;.

Ningmitai Capsule is a classical patent medicine prepared from multiple effective ingredients of Chinese herbal medicine, with a wide range of biological activities and a significant efficacy in the treatment of urogenital diseases. Ningmitai Capsule has been widely applied in the management of urological and andrological diseases, with a particularly ideal effect on chronic prostatitis, since its first introduction nearly 20 years ago. With no obvious adverse effect on the male reproductive system, it has also been gaining a gradual application in the treatment of such diseases as urinary tract infections, diabetes, non-gonococcal urethritis, seminal vesiculitis, acute epididymitis, overactive bladder, hematuria, and semen non-liquefaction. Read More

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October 2017
3 Reads

Prevalence of Mycoplasma genitalium in men with urethritis in a large public hospital in Brussels, Belgium: An observational, cross-sectional study.

PLoS One 2018 26;13(4):e0196217. Epub 2018 Apr 26.

Department of Infectious Diseases, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium.

Background: Mycoplasma genitalium (MG) is a cause of urethritis. While resistance to azithromycin is increasing, routine detection of MG is not performed in Belgium, where its prevalence is unknown. The aim of this study is to determine prevalence of MG in men with urethritis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196217PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919460PMC
July 2018
2 Reads

Corymbiform syphilis associated with three other sexually transmitted infections.

An Bras Dermatol 2018 Jan-Feb;93(1):129-132

Dermatology Clinic at Santa Casa de São Paulo - São Paulo (SP), Brazil.

Secondary syphilis can have different clinical presentations, with corymbiform rash as its rarest manifestation. The disease is characterized by a central papule surrounded by smaller ones. We report the case of a man who has sex with man with corymbiform syphilis. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20186850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871380PMC
April 2018
18 Reads

Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis.

J Infect Chemother 2018 Aug 4;24(8):610-614. Epub 2018 Apr 4.

Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan.

We analyzed the 23S rRNA, gyrA and parC genes of Chlamydia trachomatis DNAs from men with urethritis and determined microbiological outcomes of an extended-release azithromycin (azithromycin-SR) regimen (2 g once daily for 1 day) and a sitafloxacin regimen (100 mg twice daily for 7 days) for chlamydial urethritis to clarify the macrolide and fluoroquinolone resistance status of clinical strains of C. trachomatis. We amplified the portions of 2 alleles of the 23S rRNA gene and the gyrA and parC genes from C. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.03.007DOI Listing
August 2018
6 Reads

A case of oropharyngeal infection in a human immunodeficiency virus positive bisexual male co-infected with human papilloma virus and .

JMM Case Rep 2018 Mar 10;5(3):e005132. Epub 2018 Jan 10.

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address and alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites.

Case Presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884959PMC
March 2018
6 Reads

Alisma canaliculatum ethanol extract suppresses inflammatory responses in LPS-stimulated macrophages, HCl/EtOH-induced gastritis, and DSS-triggered colitis by targeting Src/Syk and TAK1 activities.

J Ethnopharmacol 2018 Jun 21;219:202-212. Epub 2018 Mar 21.

Department of Genetic Engineering, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea. Electronic address:

Ethnopharmacological Relevance: Alisma canaliculatum A.Braun & C.D. Read More

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http://dx.doi.org/10.1016/j.jep.2018.03.022DOI Listing
June 2018
1 Read

[Validation of the Kit for Detecting Mycoplasma Genitalium from the Male Urethritis].

J UOEH 2018;40(1):45-52

Department of Urology, School of Medicine, University of Occupational and Environmental Health, Japan.

Mycoplasma genitalium is one of the pathogenic microorganisms in male urethritis as a sexually transmitted infection (STI). M.genitalium is detected in the urine specimens of 15-25% male patients with urethritis. Read More

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http://dx.doi.org/10.7888/juoeh.40.45DOI Listing
September 2018
3 Reads

Prevalence of asymptomatic urethritis by Chlamydia trachomatis and Neisseria gonorrhoeae and associated risk factors among males living with HIV-1.

Rev Inst Med Trop Sao Paulo 2018 Mar 8;60:e11. Epub 2018 Mar 8.

Universidade Federal do Estado do Rio de Janeiro, Centro de Ciências Biológicas e da Saúde, Rio de Janeiro, Rio de Janeiro, Brazil.

Objectives: The increase in HIV transmissibility in non-ulcerative sexually transmitted infection is already well-established. It is estimated that symptomatic carriers of N. gonorrhoeae and C. Read More

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http://dx.doi.org/10.1590/S1678-9946201860011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962100PMC
March 2018
18 Reads

Is previous azithromycin treatment associated with azithromycin resistance in ? A cross-sectional study using national surveillance data in England.

Sex Transm Infect 2018 09 6;94(6):421-426. Epub 2018 Mar 6.

National Infection Service, Public Health England, London, UK.

Objectives: It has been suggested that treatment of STIs with azithromycin may facilitate development of azithromycin resistance in (NG) by exposing the organism to suboptimal doses. We investigated whether treatment history for non-rectal (CT), non-gonococcal urethritis (NGU) or NG (proxies for azithromycin exposure) in sexual health (GUM) services was associated with susceptibility of NG to azithromycin.

Methods: Azithromycin susceptibility data from the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP 2013-2015, n=4606) and additional high-level azithromycin-resistant isolates (HL-AziR) identified by the Public Health England reference laboratory (2013-2016, n=54) were matched to electronic patient records in the national GUMCAD STI surveillance dataset (2012-2016). Read More

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http://dx.doi.org/10.1136/sextrans-2017-053461DOI Listing
September 2018
4 Reads
1 Citation
3.401 Impact Factor

Expansion of a urethritis-associated Neisseria meningitidis clade in the United States with concurrent acquisition of N. gonorrhoeae alleles.

BMC Genomics 2018 03 2;19(1):176. Epub 2018 Mar 2.

Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: Increased reports of Neisseria meningitidis urethritis in multiple U.S. cities during 2015 have been attributed to the emergence of a novel clade of nongroupable N. Read More

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http://dx.doi.org/10.1186/s12864-018-4560-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834837PMC
March 2018
12 Reads

Prevalence of in different population groups: systematic review andmeta-analysis.

Sex Transm Infect 2018 06 9;94(4):255-262. Epub 2018 Feb 9.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Background: is a common cause of non-gonococcal non-chlamydial urethritis and cervicitis. Testing of asymptomatic populations has been proposed, but prevalence in asymptomatic populations is not well established. We aimed to estimate the prevalence of in the general population, pregnant women, men who have sex with men (MSM), commercial sex workers (CSWs) and clinic-based samples, METHODS: We searched Embase, Medline, IndMED, African Index Medicus and LILACS from 1 January 1991 to 12 July 2016 without language restrictions. Read More

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http://dx.doi.org/10.1136/sextrans-2017-053384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969327PMC
June 2018
10 Reads
3.400 Impact Factor

Highlighting the clinical need for diagnosing Mycoplasma genitalium infection.

Int J STD AIDS 2018 06 10;29(7):680-686. Epub 2018 Feb 10.

10 Guy's and St Thomas' NHS Foundation Trust, UK.

Despite Mycoplasma genitalium (MG) being increasingly recognised as a genital pathogen in men and women, awareness and utility of commercially available MG-testing has been low. The opinion of UK sexual health clinicians and allied professionals was sought on how MG-testing should be used. Thirty-two consensus statements were developed by an expert group and circulated to clinicians and laboratory staff, who were asked to evaluate their level of agreement with each statement; 75% agreement was set as the threshold for defining consensus for each statement. Read More

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http://dx.doi.org/10.1177/0956462417753527DOI Listing
June 2018
9 Reads

Was Ugo Foscolo (1778-1827) affected by alpha-1 antitrypsin deficiency?

Med Hypotheses 2018 Feb 9;111:1-3. Epub 2017 Dec 9.

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick, United Kingdom; Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Italy; UMR 7268, Laboratoire d'Anthropologie Bio-Culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, France.

Niccolò Ugo Foscolo (1778-1827), known as Ugo, is one of the masters of the Italian poetry. A writer and a revolutionary, he embraced the ideals of the French Revolution and took part in the stormy political discussions, which the fall of the Republic of Venice had provoked. Despite his poor health, Foscolo lived an adventurous life serving as a volunteer in the Guardia Nazionale and in the Napoleonic army. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03069877173121
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http://dx.doi.org/10.1016/j.mehy.2017.12.014DOI Listing
February 2018
8 Reads

Effectiveness of syndromic management for male patients with urethral discharge symptoms in Amazonas, Brazil.

An Bras Dermatol 2017 Nov-Dec;92(6):779-784

Dermatology Course, Universidade do Estado do Amazonas (UEA), Manaus, AM, Brazil.

Background: Urethral discharge syndrome (UDS) is characterized by the presence of purulent or mucopurulent urethral discharge.The main etiological agents of this syndrome are Neisseria gonorrhoeae and Chlamydia trachomatis.

Objectives: To evaluate the effectiveness of the syndromic management to resolve symptoms in male urethral discharge syndrome cases in Manaus, Amazonas, Brazil. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20175453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786390PMC
April 2018
6 Reads

Use of Pristinamycin for Macrolide-Resistant Mycoplasma genitalium Infection.

Emerg Infect Dis 2018 02;24(2):328-335

High levels of macrolide resistance and increasing fluoroquinolone resistance are found in Mycoplasma genitalium in many countries. We evaluated pristinamycin for macrolide-resistant M. genitalium in a sexual health center in Australia. Read More

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http://wwwnc.cdc.gov/eid/article/24/2/17-0902_article.htm
Publisher Site
http://dx.doi.org/10.3201/eid2402.170902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782881PMC
February 2018
24 Reads