4,502 results match your criteria Urethritis Male


The demographic and clinical profiles of women presenting with vaginal discharge syndrome at primary care facilities in South Africa: Associations with age and implications for management.

S Afr Med J 2018 Oct 2;108(10):876-880. Epub 2018 Oct 2.

Centre for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa; School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Current South African guidelines for the management of vaginal discharge syndrome (VDS) do not recommend treatment for sexually transmitted infection (STI) pathogens for women aged ≥35 years whose partners do not have male urethritis syndrome. The guideline assumes that older women are unlikely to have an STI and that their partners do not have asymptomatic infections.

Objectives: To describe the demographic, behavioural and clinical characteristics of women with VDS, comparing older women (≥35 years) with younger women, and to determine the performance of age alone as a criterion for predicting the presence of STI. Read More

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October 2018
1 Read

Chlamydia trachomatis asymptomatic urethritis recurrence among males living with HIV-1.

Rev Inst Med Trop Sao Paulo 2018 Oct 25;60:e65. Epub 2018 Oct 25.

Universidade Federal do Estado do Rio de Janeiro, Serviço de Clínica Médica, 10ᵃ Enfermaria, Rio de Janeiro, Rio de Janeiro, Brazil.

A prevalence of 3.47% of asymptomatic Chlamydia trachomatis urethritis has been previously reported among males living with HIV infection in Brazil. This study aims to assess the recurrence of C. Read More

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http://dx.doi.org/10.1590/S1678-9946201860065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201765PMC
October 2018
1 Read

Adult gonorrhea, chlamydia and syphilis prevalence, incidence, treatment and syndromic case reporting in South Africa: Estimates using the Spectrum-STI model, 1990-2017.

PLoS One 2018 15;13(10):e0205863. Epub 2018 Oct 15.

Avenir Health, Geneva, Switzerland.

Objectives: To estimate trends in prevalence and incidence of syphilis, gonorrhea and chlamydia in adult men and women in South Africa.

Methods: The Spectrum-STI tool estimated trends in prevalence and incidence of active syphilis, gonorrhea and chlamydia, fitting South African prevalence data. Results were used, alongside programmatic surveillance data, to estimate trends in incident gonorrhea cases resistant to first-line treatment, and the reporting gap of symptomatic male gonorrhea and chlamydia cases treated but not reported as cases of urethritis syndrome. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205863PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188893PMC
October 2018
4 Reads

Hyperthyroidism is not a significant risk of benign prostatic hyperplasia: A nationwide population-based study.

Medicine (Baltimore) 2018 Sep;97(39):e12459

Departments of Anesthesiology, Medical Research, Obstetrics and Gynecology, Management Office for Health Data, and Urology, China Medical University Hospital.

Benign prostatic hyperplasia (BPH) is a common disorder in the aging male population. Despite evidence that thyroid status impacts the prostate, the objective of this study was to examine whether patients with hyperthyroidism were at a greater risk for BPH.This study is a retrospective nationwide population-based cohort study of the Chinese population. Read More

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http://dx.doi.org/10.1097/MD.0000000000012459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181623PMC
September 2018
3 Reads

Microscopy of Gram-stained urethral smear in the diagnosis of urethritis: Which threshold value should be selected?

Andrologia 2018 Dec 20;50(10):e13143. Epub 2018 Sep 20.

Department of Urology, Gözde Hospital, Malatya, Turkey.

The aim of this study was to investigate the sensitivity of GSS in the diagnosis of urethritis in patients who present to the outpatient clinic with symptoms of urethritis. Sixty-three male patients who presented to our outpatient clinic with symptoms of urethritis between January and March 2018 were evaluated. Urethral smear samples obtained from patients were evaluated both by GSS examination and by Real-time Multiplex Polymerase Chain Reaction (rt-MPCR) assay. Read More

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http://dx.doi.org/10.1111/and.13143DOI Listing
December 2018
4 Reads

Primary Syphilis in the Male Urethra - A Case Report.

Clin Infect Dis 2018 Sep 10. Epub 2018 Sep 10.

Department of Epidemiology, University of Washington, Seattle, Washington, United States.

A man with nongonococcal urethritis had negative syphilis serology. We documented urethral Treponema pallidum infection using broad-range bacterial polymerase-chain-reaction and sequencing, targeted polymerase-chain-reaction, and immunofluorescence microscopy. The patient subsequently seroconverted for syphilis; symptoms resolved with penicillin. Read More

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http://dx.doi.org/10.1093/cid/ciy771DOI Listing
September 2018
4 Reads

Cross-sectional study of urethral exposures at last sexual episode associated with non-gonococcal urethritis among STD clinic patients.

Sex Transm Infect 2018 Sep 4. Epub 2018 Sep 4.

Department of Epidemiology, University of Washington, Seattle, Washington, USA.

Objective: Although (CT) and (MG) are major causes of non-gonococcal urethritis (NGU), up to 50% of cases are of unknown aetiology. We sought to identify urethral exposures at last sexual episode associated with NGU and non-CT/non-MG NGU to identify anatomical sites from which aetiologically relevant micro-organisms may be acquired.

Methods: We enrolled STD clinic patients with and without NGU assigned male sex at birth and age ≥16 into a cross-sectional study. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053634DOI Listing
September 2018
8 Reads

[Mycoplasma genitalium and male urogenital diseases: An update].

Zhonghua Nan Ke Xue 2018 Jul;24(7):645-650

Department of Andrology, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China.

Mycoplasma genitalium (MG) was first isolated by Tully from the urinary tract of the male patient with non-gonococcal urethritis (NGU) in 1981. MG is extremely difficult to be cultured and was rarely studied until the development and application of molecular biology technology. The research on MG in China is still in the primary stage. Read More

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July 2018
12 Reads

Acute kidney injury caused by systemic Neisseria gonorrhoeae infection after successful kidney transplantation.

Transpl Infect Dis 2018 Dec 21;20(6):e12987. Epub 2018 Sep 21.

Department of Urology, Sapporo City General Hospital, Sapporo, Japan.

Neisseria gonorrhoeae is one of the microbes that can causes male urethritis. This microbe is most likely to be transmitted via sexual intercourse. In men, the representative infection sites are the urethra, and oral mucosa but gonococcemia is rere. Read More

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http://doi.wiley.com/10.1111/tid.12987
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http://dx.doi.org/10.1111/tid.12987DOI Listing
December 2018
8 Reads

Is urethral microscopy useful in symptomatic male patients without urethral discharge?

Int J STD AIDS 2018 Aug 31:956462418793511. Epub 2018 Aug 31.

Sexual Health Department, the Great Western Hospital, Swindon, UK.

National guidelines recommend that male patients presenting with symptoms of urethritis or epididymo-orchitis undergo a urethral swab for microscopy. However, this is resource intensive. The aim of this audit was to determine the proportion of symptomatic patients without urethral discharge who have positive findings on urethral swab microscopy and explore associations between presenting symptoms and microscopy findings. Read More

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http://dx.doi.org/10.1177/0956462418793511DOI Listing

A microbial game of whack-a-mole: clinical case series of the urethral uncloaking phenomenon caused by Corynebacterium glucuronolyticum in men treated for Chlamydia trachomatis urethritis.

Infection 2018 Aug 30. Epub 2018 Aug 30.

Clinical Microbiology and Parasitology Unit, Polyclinic "Dr. Zora Profozić", Bosutska 19, Zagreb, 10 000, Croatia.

Corynebacterium glucuronolyticum is a rare and neglected, but increasingly recognized bacterial agent of infectious urethritis and other genitourinary syndromes in men. This is the first description of its proclivity to resurface as a cause of sustained urethritis in male patients previously treated for Chlamydia trachomatis, which represents a phenomenon that has to be differentiated from a simple post-treatment overgrowth of a colonizing agent. Read More

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http://link.springer.com/10.1007/s15010-018-1211-8
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http://dx.doi.org/10.1007/s15010-018-1211-8DOI Listing
August 2018
5 Reads

[Etiological factors for calculus-associated seminal vesiculitis: Analysis of calculus composition in 6 cases].

Zhonghua Nan Ke Xue 2018 Feb;24(2):128-132

Center of Urology and Nephrology, Ningbo First Hospital, Zhejiang University, Ningbo, Zhejiang 315010, China.

Objective: To explore the etiological factors for calculus-associated seminal vesiculitis by analyzing the composition of seminal vesicle calculus samples.

Methods: This retrospective study included 6 cases of recurrent hematospermia diagnosed with seminal vesicle calculus by non-contrast pelvic CT. The patients were aged 28 to 69 years, with persistent or recurrent hematospermia for 3 months to 6 years, and 5 of them with a history of acute urethritis. Read More

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February 2018
5 Reads

The bacterial microbiota in first-void urine from men with and without idiopathic urethritis.

PLoS One 2018 27;13(7):e0201380. Epub 2018 Jul 27.

Department of Bacteriology, Parasitology and Mycology, Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Background: Non-gonococcal urethritis (NGU) is a common syndrome in men. NGU may have several causes, but many cases are caused by sexually transmitted infections that may also cause complications in their female partners. Chlamydia trachomatis and Mycoplasma genitalium are the most common causes of NGU, but in up to 35% of the cases, none of the known viral or bacterial causes are found. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201380PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063444PMC
July 2018
2 Reads

Trends in Antimicrobial Resistance over a Ten-Year Surveillance Period, Johannesburg, South Africa, 2008⁻2017.

Antibiotics (Basel) 2018 Jul 12;7(3). Epub 2018 Jul 12.

Centre for HIV & Sexually Transmitted Infections, National Institute for Communicable Diseases, Johannesburg 2131, South Africa.

Background: In South Africa, sexually transmitted infections (STIs) are managed through a syndromic approach at primary healthcare centres (PHCs). is the predominant cause of male urethritis syndrome. We describe antimicrobial resistance patterns and trends in during a ten-year surveillance period at a large PHC in Johannesburg. Read More

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http://dx.doi.org/10.3390/antibiotics7030058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165174PMC
July 2018
1 Read

Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women.

mSphere 2018 08 27;3(3). Epub 2018 Jun 27.

Department of Immunology, Tufts University School of Medicine, Boston, Massachusetts, USA

is a bacterial pathogen responsible for the sexually transmitted infection gonorrhea. Emergence of antimicrobial resistance (AMR) of worldwide has resulted in limited therapeutic choices for this infection. Men who seek treatment often have symptomatic urethritis; in contrast, gonococcal cervicitis in women is usually minimally symptomatic, but may progress to pelvic inflammatory disease. Read More

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http://dx.doi.org/10.1128/mSphereDirect.00312-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6021601PMC
August 2018
14 Reads
1 Citation

Mutations in ParC and GyrA of moxifloxacin-resistant and susceptible Mycoplasma genitalium strains.

PLoS One 2018 8;13(6):e0198355. Epub 2018 Jun 8.

Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Macrolide or fluoroquinolone-resistant Mycoplasma genitalium is spreading worldwide. We aimed to determine the influence of single nucleotide polymorphisms (SNPs) in the quinolone resistance determining regions (QRDR) of parC and gyrA in cultured M. genitalium strains. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198355PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993279PMC
December 2018
11 Reads

Risk factors for human papillomavirus detection in urine samples of heterosexual men visiting urological clinics in Japan.

J Infect Chemother 2018 Sep 11;24(9):713-717. Epub 2018 May 11.

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Ishikawa, Japan.

Objective: The present study aimed to investigate human papillomavirus (HPV) prevalence and identify risk factors for HPV detection in urine samples among heterosexual men attending urological clinics.

Materials And Methods: Spot urine samples including initial stream were collected from 845 participants, and the cell pellets were preserved into liquid-based cytological solution. After DNA extraction from each sample, HPV-DNA amplification and genotyping were performed using Luminex multiplex polymerase chain reaction. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.04.011DOI Listing
September 2018
1 Read

[Ningmitai Capsule for the treatment of andrological diseases: Advances in studies].

Zhonghua Nan Ke Xue 2017 Oct;23(10):933-937

Department of Andrology, Jinling Hospital Affiliated to Southern Medical University / Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu 210002, China;.

Ningmitai Capsule is a classical patent medicine prepared from multiple effective ingredients of Chinese herbal medicine, with a wide range of biological activities and a significant efficacy in the treatment of urogenital diseases. Ningmitai Capsule has been widely applied in the management of urological and andrological diseases, with a particularly ideal effect on chronic prostatitis, since its first introduction nearly 20 years ago. With no obvious adverse effect on the male reproductive system, it has also been gaining a gradual application in the treatment of such diseases as urinary tract infections, diabetes, non-gonococcal urethritis, seminal vesiculitis, acute epididymitis, overactive bladder, hematuria, and semen non-liquefaction. Read More

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October 2017
2 Reads

Prevalence of Mycoplasma genitalium in men with urethritis in a large public hospital in Brussels, Belgium: An observational, cross-sectional study.

PLoS One 2018 26;13(4):e0196217. Epub 2018 Apr 26.

Department of Infectious Diseases, CHU Saint-Pierre, Université Libre de Bruxelles (ULB), Brussels, Belgium.

Background: Mycoplasma genitalium (MG) is a cause of urethritis. While resistance to azithromycin is increasing, routine detection of MG is not performed in Belgium, where its prevalence is unknown. The aim of this study is to determine prevalence of MG in men with urethritis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196217PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919460PMC

Corymbiform syphilis associated with three other sexually transmitted infections.

An Bras Dermatol 2018 Jan-Feb;93(1):129-132

Dermatology Clinic at Santa Casa de São Paulo - São Paulo (SP), Brazil.

Secondary syphilis can have different clinical presentations, with corymbiform rash as its rarest manifestation. The disease is characterized by a central papule surrounded by smaller ones. We report the case of a man who has sex with man with corymbiform syphilis. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20186850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871380PMC
April 2018
15 Reads

Macrolide and fluoroquinolone resistance is uncommon in clinical strains of Chlamydia trachomatis.

J Infect Chemother 2018 Aug 4;24(8):610-614. Epub 2018 Apr 4.

Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan.

We analyzed the 23S rRNA, gyrA and parC genes of Chlamydia trachomatis DNAs from men with urethritis and determined microbiological outcomes of an extended-release azithromycin (azithromycin-SR) regimen (2 g once daily for 1 day) and a sitafloxacin regimen (100 mg twice daily for 7 days) for chlamydial urethritis to clarify the macrolide and fluoroquinolone resistance status of clinical strains of C. trachomatis. We amplified the portions of 2 alleles of the 23S rRNA gene and the gyrA and parC genes from C. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.03.007DOI Listing
August 2018
3 Reads

A case of oropharyngeal infection in a human immunodeficiency virus positive bisexual male co-infected with human papilloma virus and .

JMM Case Rep 2018 Mar 10;5(3):e005132. Epub 2018 Jan 10.

Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Management strategies for sexually transmitted infections (STIs) in their extragenital forms address and alone; whereas increased rates of isolation of other STI agents have been reported from various parts of the world. Their extragenital presence as a reservoir of infection emphasizes the need to screen and treat them at these sites.

Case Presentation: A 35-year-old human immunodeficiency virus 1 infected bisexual male presented with urethral discharge and multiple ano-genital warts. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884959PMC
March 2018
5 Reads

Alisma canaliculatum ethanol extract suppresses inflammatory responses in LPS-stimulated macrophages, HCl/EtOH-induced gastritis, and DSS-triggered colitis by targeting Src/Syk and TAK1 activities.

J Ethnopharmacol 2018 Jun 21;219:202-212. Epub 2018 Mar 21.

Department of Genetic Engineering, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon 16419, Republic of Korea. Electronic address:

Ethnopharmacological Relevance: Alisma canaliculatum A.Braun & C.D. Read More

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http://dx.doi.org/10.1016/j.jep.2018.03.022DOI Listing
June 2018
1 Read

[Validation of the Kit for Detecting Mycoplasma Genitalium from the Male Urethritis].

J UOEH 2018;40(1):45-52

Department of Urology, School of Medicine, University of Occupational and Environmental Health, Japan.

Mycoplasma genitalium is one of the pathogenic microorganisms in male urethritis as a sexually transmitted infection (STI). M.genitalium is detected in the urine specimens of 15-25% male patients with urethritis. Read More

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http://dx.doi.org/10.7888/juoeh.40.45DOI Listing
September 2018
2 Reads

Prevalence of asymptomatic urethritis by Chlamydia trachomatis and Neisseria gonorrhoeae and associated risk factors among males living with HIV-1.

Rev Inst Med Trop Sao Paulo 2018 Mar 8;60:e11. Epub 2018 Mar 8.

Universidade Federal do Estado do Rio de Janeiro, Centro de Ciências Biológicas e da Saúde, Rio de Janeiro, Rio de Janeiro, Brazil.

Objectives: The increase in HIV transmissibility in non-ulcerative sexually transmitted infection is already well-established. It is estimated that symptomatic carriers of N. gonorrhoeae and C. Read More

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http://dx.doi.org/10.1590/S1678-9946201860011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962100PMC
March 2018
12 Reads

Expansion of a urethritis-associated Neisseria meningitidis clade in the United States with concurrent acquisition of N. gonorrhoeae alleles.

BMC Genomics 2018 03 2;19(1):176. Epub 2018 Mar 2.

Division of Bacterial Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Background: Increased reports of Neisseria meningitidis urethritis in multiple U.S. cities during 2015 have been attributed to the emergence of a novel clade of nongroupable N. Read More

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http://dx.doi.org/10.1186/s12864-018-4560-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5834837PMC
March 2018
6 Reads

Prevalence of in different population groups: systematic review andmeta-analysis.

Sex Transm Infect 2018 06 9;94(4):255-262. Epub 2018 Feb 9.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Background: is a common cause of non-gonococcal non-chlamydial urethritis and cervicitis. Testing of asymptomatic populations has been proposed, but prevalence in asymptomatic populations is not well established. We aimed to estimate the prevalence of in the general population, pregnant women, men who have sex with men (MSM), commercial sex workers (CSWs) and clinic-based samples, METHODS: We searched Embase, Medline, IndMED, African Index Medicus and LILACS from 1 January 1991 to 12 July 2016 without language restrictions. Read More

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http://dx.doi.org/10.1136/sextrans-2017-053384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969327PMC
June 2018
8 Reads
3.400 Impact Factor

Was Ugo Foscolo (1778-1827) affected by alpha-1 antitrypsin deficiency?

Med Hypotheses 2018 Feb 9;111:1-3. Epub 2017 Dec 9.

Warwick Medical School, Microbiology and Infection Unit, The University of Warwick, United Kingdom; Legal Medicine Section, Department of Public Health and Paediatric Sciences, University of Turin, Italy; UMR 7268, Laboratoire d'Anthropologie Bio-Culturelle, Droit, Etique & Santé (Adés), Faculté de Médecine de Marseille, France.

Niccolò Ugo Foscolo (1778-1827), known as Ugo, is one of the masters of the Italian poetry. A writer and a revolutionary, he embraced the ideals of the French Revolution and took part in the stormy political discussions, which the fall of the Republic of Venice had provoked. Despite his poor health, Foscolo lived an adventurous life serving as a volunteer in the Guardia Nazionale and in the Napoleonic army. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03069877173121
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http://dx.doi.org/10.1016/j.mehy.2017.12.014DOI Listing
February 2018
8 Reads

Effectiveness of syndromic management for male patients with urethral discharge symptoms in Amazonas, Brazil.

An Bras Dermatol 2017 Nov-Dec;92(6):779-784

Dermatology Course, Universidade do Estado do Amazonas (UEA), Manaus, AM, Brazil.

Background: Urethral discharge syndrome (UDS) is characterized by the presence of purulent or mucopurulent urethral discharge.The main etiological agents of this syndrome are Neisseria gonorrhoeae and Chlamydia trachomatis.

Objectives: To evaluate the effectiveness of the syndromic management to resolve symptoms in male urethral discharge syndrome cases in Manaus, Amazonas, Brazil. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20175453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786390PMC
April 2018
6 Reads

A Case Study on Successful Ayurvedic Management of a Rare Case of Reiter's Syndrome.

Anc Sci Life 2017 Apr-Jun;36(4):225-228

Department of Kayachikitsa, Mahatma Gandhi Ayurved College, Hospital and Research Centre, DMIMS (DU), Wardha, Maharashtra, India.

Reiter's syndrome is a clinical syndrome of arthritis, urethritis, conjunctivitis, and mucocutaneous lesions. Skin and mucosal involvement is observed in about 10% of the cases. A 34-year-old male was brought in severe condition. Read More

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http://dx.doi.org/10.4103/asl.ASL_89_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726191PMC
December 2017
3 Reads

The Etiology of Male Urethral Discharge in Zimbabwe: Results from the Zimbabwe STI Etiology Study.

Sex Transm Dis 2018 01;45(1):56-60

From the *Surveillance, Evaluation, Assessment, and Monitoring (SEAM) Project, Department of Community Medicine, College of Medicine, University of Zimbabwe, Harare, Zimbabwe; †Colorado School of Public Health, University of Colorado Denver; ‡Rietmeijer Consulting, Denver, CO; §Zimbabwe Ministry of Health and Child Care; ¶Zimbabwe Community Health Intervention Research (ZiCHIRe) Project; ∥US Centers for Disease Control and Prevention, Harare, Zimbabwe, Zimbabwe; **Western Sydney Sexual Health Centre, Sydney, Australia; and ††School of Medicine, University of Washington, Seattle, WA.

Introduction: Sexually transmitted infections (STIs) are managed syndromically in most developing countries. In Zimbabwe, men presenting with urethral discharge are treated with a single intramuscular dose of kanamycin or ceftriaxone in combination with a week's course of oral doxycycline. This study was designed to assess the current etiology of urethral discharge and other STIs to inform current syndromic management regimens. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000696DOI Listing
January 2018
13 Reads

Case Report of Urethritis in a Male Patient Infected with Two Different Isolates of Multiple Drug-Resistant .

Front Med (Lausanne) 2017 8;4:194. Epub 2017 Nov 8.

Faculty of Medicine, Department of Dermatology and Venereology, Tanta University, Tanta, Egypt.

We report a brief description of a case suffering from bacterial urethritis, conjunctivitis, and arthritis, caused by two different isolates of multiple drug-resistant . Initial diagnosis was dependent on the patient history, clinical findings, symptoms, and the bacteriological data. Polymerase chain reaction confirmed the identification of the pathogens. Read More

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http://dx.doi.org/10.3389/fmed.2017.00194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5682295PMC
November 2017
5 Reads

GyrA and/or ParC alterations of Haemophilus influenzae strains isolated from the urethra of men with acute urethritis.

J Infect Chemother 2018 Mar 11;24(3):232-235. Epub 2017 Nov 11.

Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan. Electronic address:

Of 73 clinical strains of Haemophilus influenzae isolated from the urethra of men with urogenital infections, we enrolled 6 strains (8.2%) with levofloxacin (LVFX) minimum inhibitory concentrations (MICs) of ≥0.03 μg/ml in this study. Read More

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http://dx.doi.org/10.1016/j.jiac.2017.10.013DOI Listing
March 2018
2 Reads

[Diagnostic issues of lymphogranuloma venereum: A case series of 5 patients].

Rev Med Interne 2017 Dec 8;38(12):794-799. Epub 2017 Nov 8.

Service de médecine interne, hôpital Ambroise-Paré, AP-HP, 92100 Boulogne-Billancourt, France. Electronic address:

Introduction: Lymphogranuloma venereum (LG) is a sexually transmitted infection (STI) caused by Chlamydia trachomatis L serovar.

Methods: These five consecutive cases aim to highlight the risk of LG misdiagnosis, in case of initial presentation with isolated inguinal adenitis.

Results: Five men (mean age: 30±7 years) were seen in an internal medicine department, for inguinal adenopathy. Read More

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http://dx.doi.org/10.1016/j.revmed.2017.09.014DOI Listing
December 2017
3 Reads

Manual vs. automated implantation of seeds in prostate brachytherapy: Oncologic results from a single-center study.

Brachytherapy 2018 Jan - Feb;17(1):214-220

Department of Radiation Oncology, Institut Bergonié, Comprehensive Cancer Center, Bordeaux Cedex, France.

Purpose: The objective of this study was to study survival and tolerance of prostate cancer patients treated with I permanent interstitial brachytherapy by automated vs. manual implantation of seeds.

Methods And Materials: Between 2002 and 2010, 349 selected patients were treated with I brachytherapy by the same team: from 2002 to April 2005, 65 patients with linked seeds and then 284 patients treated using Nucletron First System automated implantation. Read More

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http://dx.doi.org/10.1016/j.brachy.2017.09.013DOI Listing
July 2018
15 Reads

Prevalence of rheumatic musculoskeletal symptoms in rural and urban areas : a cross-sectional study in northern India.

Int J Rheum Dis 2017 Nov 27;20(11):1638-1647. Epub 2017 Oct 27.

Hind Medical College, Lucknow, Uttar Pradesh, India.

Objectives: To study the prevalence of rheumatic musculoskeletal symptoms in rural and urban areas of Lucknow.

Method: The survey was carried out in a cluster of rural (n = 5118) and urban (n = 5053) communities of Lucknow through a door-to-door survey. Demographic data were collected and subjects with musculoskeletal pain (MSK pain) were identified. Read More

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http://doi.wiley.com/10.1111/1756-185X.13189
Publisher Site
http://dx.doi.org/10.1111/1756-185X.13189DOI Listing
November 2017
7 Reads

Multidrug-resistant infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.

Euro Surveill 2017 Oct;22(42)

Department of Clinical Microbiology, Hvidovre Hospital, Copenhagen, Denmark.

We describe a multidrug-resistant infection with ceftriaxone resistance and azithromycin intermediate resistance in a heterosexual man in Denmark, 2017. Whole genome sequencing of the strain GK124 identified MSLT ST1903, NG-MAST ST1614 and all relevant resistance determinants including similar penA resistance mutations previously described in ceftriaxone-resistant gonococcal strains. Although treatment with ceftriaxone 0. Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2017.22.42.17-00659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710115PMC
October 2017
9 Reads

Evaluation of the Microbiological Efficacy of a Single 2-Gram Dose of Extended-Release Azithromycin by Population Pharmacokinetics and Simulation in Japanese Patients with Gonococcal Urethritis.

Antimicrob Agents Chemother 2018 Jan 21;62(1). Epub 2017 Dec 21.

Laboratory of Pharmaceutics, Department of Biomedical Pharmaceutics, Gifu Pharmaceutical University, Gifu, Japan

The objective of this study was to analyze the relationship between the pharmacokinetic (PK)/pharmacodynamic (PD) parameters of a single 2-g dose of extended-release formulation of azithromycin (AZM-SR) and its microbiological efficacy against gonococcal urethritis. Fifty male patients with gonococcal urethritis were enrolled in this study. In 36 patients, the plasma AZM concentrations were measured using liquid chromatography-tandem mass spectrometry, the AZM MIC values for the isolates were determined, and the microbiological outcomes were assessed. Read More

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http://dx.doi.org/10.1128/AAC.01409-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5740364PMC
January 2018
1 Read

Diagnosis of Trichomoniasis in Male Patients on Performing Nested Polymerase Chain Reaction.

Turkiye Parazitol Derg 2017 Sep;41(3):130-134

Department of Parasitology, Turgut Özal Medical Center, İnönü University Faculty of Medicine Malatya, Turkey. mutluyaraycan.

Objective: Trichomoniasis is a parasitic infection that occurs with the settlement of Trichomonas vaginalis in female and male urinary and reproductive tracts. This infection is generally asymptomatic in males, and males are thought to be a carrier for the transmission of infection. In this study, our aim was to detect trichomoniasis using nested polymerase chain reaction among males who were referred to a hospital with suspected urinary tract infection. Read More

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http://dx.doi.org/10.5152/tpd.2017.5016DOI Listing
September 2017
11 Reads

Preliminary Experience with Instillation of Triamcinolone Acetonide into the Urethra for Idiopathic Urethritis: A Prospective Pilot Study.

J Laparoendosc Adv Surg Tech A 2017 Nov 12;27(11):1217-1221. Epub 2017 Oct 12.

Department of Pediatric Urology, Leeds General Infirmary , Leeds, United Kingdom .

Background: Idiopathic bulbar urethritis (IBU) is characterized by hematuria ± dysuria without infection. Symptoms result from inflammation of the bulbar urethra, distal to external sphincter. IBU is difficult to manage and there is no recommended therapy. Read More

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http://www.liebertpub.com/doi/10.1089/lap.2017.0064
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http://dx.doi.org/10.1089/lap.2017.0064DOI Listing
November 2017
1 Read

Antimicrobial susceptibility profile of isolated in Cotonou, Benin (2015-2017).

Sex Transm Infect 2018 02 11;94(1):20. Epub 2017 Oct 11.

Centre de recherche du CHU de Québec, Université Laval, Québec, Canada.

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2017-053340
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http://dx.doi.org/10.1136/sextrans-2017-053340DOI Listing
February 2018
6 Reads

Increase in sexually transmitted infections in a cohort of outpatient HIV-positive men who have sex with men in the Parisian region.

Med Mal Infect 2017 Nov 22;47(7):490-493. Epub 2017 Sep 22.

Hospital Foch, 40, rue Worth, 92151 Suresnes, France.

Objective: To describe the increased incidence of sexually transmitted infections (STIs) in a cohort of HIV-infected men who have sex with men (MSM), followed in a tertiary hospital of the Île-de-France region.

Materials And Methods: We performed a monocentric, retrospective, and prospective study. We included symptomatic HIV-infected MSM patients who consulted for their annual consultation. Read More

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http://dx.doi.org/10.1016/j.medmal.2017.06.004DOI Listing
November 2017
6 Reads

Comparison of the risk factors and HPV types in males with anogenital warts with and without involvement of the urethral meatus in western Iran.

Acta Dermatovenerol Alp Pannonica Adriat 2017 09;26(3):55-58

Kermanshah University of Medical Sciences (KUMS), Kermanshah, Iran.

Background: Human papillomavirus (HPV)-induced lesions rarely develop in the urethral meatus (UM); however, their eradication can be problematic.

Methods: A total of 22 patients with anogenital warts (AGWs) in the UM region and 22 patients with AGWs located at other anatomical sites were included in this cross-sectional study. The presence of human papillomavirus (HPV) types in biopsy samples was determined using the HPV Easy typing kit (GenID GmbH, Germany). Read More

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September 2017
8 Reads

Clinical and analytical evaluation of the new Aptima Mycoplasma genitalium assay, with data on M. genitalium prevalence and antimicrobial resistance in M. genitalium in Denmark, Norway and Sweden in 2016.

Clin Microbiol Infect 2018 May 18;24(5):533-539. Epub 2017 Sep 18.

Infection Preparedness, Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Objectives: Mycoplasma genitalium (MG) causes urethritis and cervicitis, potentially causing reproductive complications. Resistance in MG to first-line (azithromycin) and second-line (moxifloxacin) treatment has increased. We examined the clinical and analytical performance of the new Conformité Européene (CE)/in vitro diagnostics (IVD) Aptima Mycoplasma genitalium assay (CE/IVD AMG; Hologic); the prevalence of MG, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG); and MG resistance to azithromycin and moxifloxacin in Denmark, Norway and Sweden in 2016. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1198743X173050
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http://dx.doi.org/10.1016/j.cmi.2017.09.006DOI Listing
May 2018
8 Reads

Compliance with the primary health care treatment guidelines and the essential medicines list in the management of sexually transmitted infections in correctional centres in South Africa: findings and implications.

Expert Rev Anti Infect Ther 2017 10;15(10):963-972

a School of Pharmacy , Sefako Makgatho Health Sciences University , Pretoria , South Africa.

Background: The emergence of antimicrobial resistance (AMR) is a global concern and a growing health crisis. Additionally, evidence has shown that non-compliance to treatment guidelines, especially in the management of communicable diseases such as sexually transmitted infections (STIs), has the potential of further enhancing AMR rates. Data on the extent of these challenges in Primary Health Care (PHC) facilities in correctional centres in South Africa (SA) is limited. Read More

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http://dx.doi.org/10.1080/14787210.2017.1382354DOI Listing
October 2017
30 Reads

Inhibitory effects of Dianthi Herba ethanolic extract on inflammatory and nociceptive responses in murine macrophages and mouse models of abdominal writhing and ear edema.

J Ethnopharmacol 2018 Jan 14;211:375-383. Epub 2017 Sep 14.

Korean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine, 70, Cheomdanro, Dong-gu, Daegu 41062, Republic of Korea. Electronic address:

Ethnopharmacological Relevance: Dianthi Herba is a traditional herbal medicine used to treat inflammatory-related diseases including acute pyelonephritis, cystitis, laryngopharyngitis, and urethritis.

Aim Of The Study: We investigated the effects of Dianthi Herba ethanolic extract (DH) on lipopolysaccharide (LPS)-mediated inflammatory responses in murine macrophages including RAW 264.7 cell line and mouse peritoneal macrophages as well as nociceptive and edema mouse models. Read More

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http://dx.doi.org/10.1016/j.jep.2017.09.010DOI Listing
January 2018
16 Reads

Genomic Characterization of Urethritis-Associated Neisseria meningitidis Shows that a Wide Range of N. meningitidis Strains Can Cause Urethritis.

J Clin Microbiol 2017 12 13;55(12):3374-3383. Epub 2017 Sep 13.

Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA

, typically a resident of the oro- or nasopharynx and the causative agent of meningococcal meningitis and meningococcemia, is capable of invading and colonizing the urogenital tract. This can result in urethritis, akin to the syndrome caused by its sister species, , the etiologic agent of gonorrhea. Recently, meningococcal strains associated with outbreaks of urethritis were reported to share genetic characteristics with the gonococcus, raising the question of the extent to which these strains contain features that promote adaptation to the genitourinary niche, making them gonococcus-like and distinguishing them from other strains. Read More

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http://jcm.asm.org/lookup/doi/10.1128/JCM.01018-17
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http://dx.doi.org/10.1128/JCM.01018-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703804PMC
December 2017
18 Reads

'Haemophilus quentini' in the urethra of men complaining of urethritis symptoms.

J Infect Chemother 2018 Jan 8;24(1):71-74. Epub 2017 Sep 8.

Department of Urology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan. Electronic address:

We isolated a cryptic genospecies of Haemophilus influenzae referred to as 'Haemophilus quentini' in the urethra of 3 men complaining of urethritis symptoms. H. influenzae strains, which had been isolated from the urethra in 77 of 1518 men complaining of urethritis symptoms, identified by the conventional test, and stored, were re-cultured for this study. Read More

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http://dx.doi.org/10.1016/j.jiac.2017.08.007DOI Listing
January 2018
4 Reads

Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance Detection and Clinical Implications in a Selected Cohort in New Zealand.

J Clin Microbiol 2017 11 6;55(11):3242-3248. Epub 2017 Sep 6.

Canterbury Health Laboratories, Canterbury District Health Board, Christchurch, New Zealand.

has been associated with infections of the genitourinary tract, and prevalence is secondary to The clinical observation of increasing treatment failure indicating antibiotic resistance, especially in cases of recurrent urethritis, has been confirmed by molecular testing. Mutations in the 23S rRNA gene can cause macrolide resistance, and topoisomerase/gyrase mutations can cause fluoroquinolone resistance. In this study, 115 DNA-positive samples were analyzed. Read More

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http://dx.doi.org/10.1128/JCM.01087-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654908PMC
November 2017
4 Reads