5,927 results match your criteria Urethral Cancer


Assessment of dose to functional sub-structures in the lower urinary tract in locally advanced cervical cancer radiotherapy.

Phys Med 2019 Feb 13. Epub 2019 Feb 13.

Department of Oncology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.

Purpose: To provide an analysis of dose distribution in sub-structures that could be responsible for urinary toxicity after Image-Guided Adaptive BrachyTherapy (IGABT) in Locally Advanced Cervical Cancer (LACC).

Methods: 105 LACC patients treated with radiochemotherapy and IGABT were selected. Sub-structures (bladder wall, trigone, bladder neck, urethra) were contoured on IGABT-planning MRIs. Read More

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http://dx.doi.org/10.1016/j.ejmp.2019.01.017DOI Listing
February 2019
1 Read

A single-center, prospective, randomized clinical trial to investigate the optimal removal time of the urinary catheter after laparoscopic anterior resection of the rectum: study protocol for a randomized controlled trial.

Trials 2019 Feb 15;20(1):133. Epub 2019 Feb 15.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, People's Republic of China.

Background: Urinary catheter placement is essential before laparoscopic anterior resection for rectal cancer. Whether early removal of the catheter increases the incidence of urinary retention and urinary tract infection (UTI) is not clear. This study aims to determine the optimal time for removal of the urinary catheter after laparoscopic anterior resection of the rectum. Read More

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http://dx.doi.org/10.1186/s13063-019-3210-1DOI Listing
February 2019
2.117 Impact Factor

[Urodynamics study in patients with urinary incontinence, after surgical treatment of localized prostate cancer].

Urologiia 2018 Dec(6):14-18

MBUZ Clinical and diagnostic Center Zdorovie, Rostov-on-Don, Russia.

Aim: Radical treatment of prostate cancer (PCa) is often associated with the development of urinary incontinence (UI). The etiology of UI after prostatectomy is multifactorial and can be caused by both urethral sphincter deficiency and bladder dysfunction. To date, there are no comparative studies of the development of UI in patients after either organ-preserving treatment or radical prostatectomy (RP). Read More

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December 2018
1 Read

A Rare Case of Advanced Urethral Diverticular Adenocarcinoma and a Review of Treatment Modalities.

J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619828408

1 Brookdale University Hospitals and Medical Center, New York, NY, USA.

Female urethral diverticular cancer is a very rare entity with only around 100 cases reported so far in literature and accounts for <1% of all malignancies. In this article, we present a 47-year-old African American female with repeated hospital visits for urinary retention, hematuria, and urinary tract infections. Initial computed tomography imaging and cystoscopy was unremarkable except for a distended urinary bladder. Read More

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http://dx.doi.org/10.1177/2324709619828408DOI Listing
February 2019
1 Read

Malignant lymphoma of the bladder with bilateral hydronephrosis.

Rare Tumors 2019 22;11:2036361318825165. Epub 2019 Jan 22.

Department of Urology, Kurume University School of Medicine, Kurume, Japan.

Lymphoma of the urinary bladder is uncommon, and upper urinary tract obstruction due to lymphoma is rare. Herein, we report a case of malignant lymphoma of the bladder with bilateral hydronephrosis in a 67-year-old female who presented with oliguria. Ultrasonography and computed tomography demonstrated a thickened posterior bladder wall and bilateral hydronephrosis. Read More

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http://dx.doi.org/10.1177/2036361318825165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348503PMC
January 2019
4 Reads

Optimized penile surface mold brachytherapy using latest stereolithography techniques: A single-institution experience.

Brachytherapy 2019 Feb 1. Epub 2019 Feb 1.

University of Toronto, Toronto, Ontario, Canada; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address:

Purpose: To describe a technique of penile surface mold high-dose-rate (HDR) brachytherapy and early outcomes.

Methods And Materials: Five patients diagnosed with a T1aN0 squamous cell carcinoma of the penis were treated using a penile surface mold HDR brachytherapy technique. A negative impression of the penis was obtained using dental alginate. Read More

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http://dx.doi.org/10.1016/j.brachy.2019.01.002DOI Listing
February 2019
1.987 Impact Factor

Bevacizumab is associated with delayed anastomotic leak after low anterior resection with preoperative radiotherapy for rectal cancer: a case report.

Surg Case Rep 2019 Jan 31;5(1):14. Epub 2019 Jan 31.

Department of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitamashi, Saitamaken, 330-8503, Japan.

Background: Bevacizumab is an anti-angiogenesis agent used to treat patients with metastatic colorectal cancer and is associated with a variety of complications. We present a patient with rectal cancer who developed a delayed anastomotic leak more than 5 years after undergoing low anterior resection.

Case Report: A 78-year-old man with hematochezia was diagnosed with two synchronous rectal cancers 7 years prior to presentation. Read More

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http://dx.doi.org/10.1186/s40792-019-0573-1DOI Listing
January 2019
1 Read

Urethral metastasis with neuroendocrine differentiation in a patient with prostate cancer treated with hormone deprivation.

Indian J Urol 2019 Jan-Mar;35(1):75-77

Department of Histopathology, Max Super Speciality Hospital, New Delhi, India.

Adenocarcinoma prostate treated with hormone deprivation may evolve into a neuroendocrine differentiated tumor. Usually visceral metastasis are seen in neuroendocrine tumors. We present a case of neuroendocrine differentiated urethral metastasis from a hormone deprived prostate cancer. Read More

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http://dx.doi.org/10.4103/iju.IJU_175_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334586PMC
January 2019

Association Between Preoperative Magnetic Resonance Imaging-based Urethral Parameters and Continence Recovery Following Robot-assisted Radical Prostatectomy.

Eur Urol Focus 2019 Jan 25. Epub 2019 Jan 25.

Royal Marsden Hospital, London, UK.

Background: Studies demonstrated the significance of membranous urethral length (MUL) as a predictor of continence following robot-assisted radical prostatectomy (RARP). There are other magnetic resonance imaging (MRI) parameters that might be linked to continence outcome.

Objective: To evaluate the association between preoperative urethral parameters on MRI and continence outcome, to estimate the risk of incontinence using different cut-off values, and to assess interobserver variability in measuring urethral parameters. Read More

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http://dx.doi.org/10.1016/j.euf.2019.01.011DOI Listing
January 2019

Preliminary results of using a voice-controlled robotic camera driver during 3D laparoscopic radical prostatectomy.

Cent European J Urol 2018 27;71(4):394-398. Epub 2018 Dec 27.

Department of Urology, The Faculty of Medicine and Health Sciences, University of Zielona Góra, Zielona Góra, Poland.

Introduction: During laparoscopic procedures, the surgeon's control on target field visualization as well as optimal and steady vision can be achieved by using a camera holder. The article presents our preliminary experience with the use of a voice controlled robotic camera holder during 3D laparoscopic radical prostatectomy (3D LRP).

Material And Method: Thirty patients were prospectively enrolled and underwent either 3D LRP with the use of a voice controlled robotic camera holder (study group) or 3D LRP with the surgeon holding the camera (control group). Read More

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http://dx.doi.org/10.5173/ceju.2018.1800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338813PMC
December 2018

Radical prostatectomy performed via robotic, transperitoneal and extraperitoneoscopic approaches: functional and early oncological outcomes.

Cent European J Urol 2018 30;71(4):378-385. Epub 2018 Oct 30.

Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.

Introduction: Oncological remission along with high postoperative functionality [continence and erectile function (EF)] are the main aspects of prostate cancer (PCa) treatment. The aim of this study was to compare functional and oncological treatment results achieved after a nerve-sparing radical prostatectomy (RP) via transperitoneal (TPRP), extraperitoneal (EPRP) and robot-assisted (RARP) approach.

Material And Methods: From March 2015 to March 2016, 507 RP were performed at the Institute for Urology and Reproductive Health (Moscow, Russia). Read More

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http://dx.doi.org/10.5173/ceju.2018.1739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338822PMC
October 2018
1 Read

Vesicourethral anastomosis including rhabdosphincter in retropubic radical prostatectomy: Technique and results.

Arch Ital Urol Androl 2019 Jan 18;90(4):249-253. Epub 2019 Jan 18.

Haydarpaşa Numune Training and Research Hospital, Department of Urology, Istanbul.

Objective: Retropubic radical prostatectomy (RRP) is still widely used in clinical practice in localized prostate cancer because of its high oncological success. The aim of this study was to define the continence status in patients where rhabdosphincter was included in the vesicourethral anastomosis.

Materials And Methods: Between November 2004 and September 2010, 90 cases who underwent RRP by the same surgeon in our clinic were taken into the study. Read More

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http://dx.doi.org/10.4081/aiua.2018.4.249DOI Listing
January 2019
1 Read

Primary urothelial carcinoma of the prostate: A rare case report.

Medicine (Baltimore) 2019 Jan;98(3):e14155

Department of Urology, The First Affiliated Hospital of Anhui Medical University.

Rationale: Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam. Read More

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http://dx.doi.org/10.1097/MD.0000000000014155DOI Listing
January 2019
1 Read
5.723 Impact Factor

Primary Small Cell Neuroendocrine Tumor Within a Urethral Diverticulum.

Obstet Gynecol 2019 Feb;133(2):308-311

Department of Obstetrics and Gynecology, Saint Louis University School of Medicine, and Saint Louis University School of Medicine, St. Louis, Missouri.

Background: Primary small cell neuroendocrine carcinoma of the urinary tract is a very rare cancer, accounting for fewer than 0.5% of urinary tract tumors. These are aggressive neoplasms with high rates of metastases. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003054DOI Listing
February 2019
1 Read

5-Year Outcomes of a Phase I Dose Escalation Study Using Stereotactic Body Radiosurgery for Patients with Low and Intermediate Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 Jan 3. Epub 2019 Jan 3.

Department of Radiation Oncology, Department of Medical Physics, Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, N.Y. 10065; Department of Radiation Oncology, Montefiore Medical Center, Bronx, New York; Department of Radiation Medicine, Northwell Health, Lenox Hill Hospital, New York, N.Y.

Purpose: To report toxicity outcomes, PSA relapse, and cumulative incidence-post-treatment biopsy results among patients treated on a prospective dose escalation study using ultra-hypofractionated stereotactic body radiotherapy (SBRT) for patients with low/intermediate risk prostate cancer.

Methods And Materials: 136 patients were accrued to a Phase I dose escalation study to determine the tolerance of escalating radiation dose levels of SBRT for the treatment of localized prostate cancer. The initial dose level was 32. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.045DOI Listing
January 2019
5 Reads

Health-related Quality of Life and Toxicity After Single-fraction High-dose-rate Brachytherapy With External Beam Radiotherapy for Localized and Locally Advanced Prostate Cancer.

Anticancer Res 2019 Jan;39(1):477-486

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan

Background/aim: To evaluate the treatment outcomes, toxicity and health-related quality of life (HRQOL) in prostate cancer (PCa) patients who underwent single-fraction high-dose-rate brachytherapy (single-fraction HDR-BT) with external beam radiotherapy (EBRT).

Materials And Methods: From April 2014 to October 2017, treatment outcomes and toxicity of 85 patients who underwent single-fraction HDR-BT of 13 Gy, followed by 46 Gy EBRT in 23 fractions, were examined. HRQOL of 53 patients was evaluated using the Expanded Prostate Cancer Index Composite (EPIC), International Prostate Symptom Score (IPSS)/QOL index, International Index of Erectile Function 5 (IIEF-5), and 36-Item Short Form Survey (SF-36) scores through one year. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13137DOI Listing
January 2019
6 Reads

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

J Magn Reson Imaging 2018 Dec 25. Epub 2018 Dec 25.

Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

Background: Post-radiotherapy locally recurrent prostate cancer (PCa) patients are candidates for focal salvage treatment. Multiparametric MRI (mp-MRI) is attractive for tumor localization. However, radiotherapy-induced tissue changes complicate image interpretation. Read More

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http://dx.doi.org/10.1002/jmri.26581DOI Listing
December 2018
3 Reads

Prognosis of rare pathological primary urethral carcinoma.

Cancer Manag Res 2018 7;10:6815-6822. Epub 2018 Dec 7.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China,

Purpose: Urethral carcinoma (UC), as a rare tumor, is not widely studied. There have been no systematic studies of rare pathological types of UC. We conducted this study to further investigate rare pathological types of primary urethral carcinoma (PUC). Read More

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http://dx.doi.org/10.2147/CMAR.S184197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289122PMC
December 2018
2 Reads

Pelvic Complications After Prostate Cancer Radiation Therapy and Their Management: An International Collaborative Narrative Review.

Eur Urol 2019 Mar 17;75(3):464-476. Epub 2018 Dec 17.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Institute for Health Policy, Management & Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Context: Radiotherapy used for treating localized prostate cancer is effective at prolonging cancer-specific and overall survival. Still, acute and late pelvic toxicities are a concern, with gastrointestinal (GI) and genitourinary (GU) sequelae being most common as well as other pelvic complications.

Objective: To present a critical review of the literature regarding the incidence and risk factors of pelvic toxicity following primary radiotherapy for prostate cancer and to provide a narrative review regarding its management. Read More

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http://dx.doi.org/10.1016/j.eururo.2018.12.003DOI Listing
March 2019
3 Reads

Cystic metastasis of prostate cancer: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13697

Department of Radiology.

Rationale: Prostate cancer often metastasizes (most commonly to the pelvic lymph nodes and axial skeleton); however, metastases to the pelvic cavity as a solitary mass are unusual. While metastatic prostate cancer is unconventional in pelvic cavity, cystic pelvic lesions are even more scarce. Accurate identification of cystic metastasis can be helpful in management of prostate cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000013697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320181PMC
December 2018
5.723 Impact Factor

Urethra and Ejaculation Preserving Robot-assisted Simple Prostatectomy: Near-infrared Fluorescence Imaging-guided Madigan Technique.

Eur Urol 2019 Mar 12;75(3):492-497. Epub 2018 Dec 12.

Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.

Background: With the increasing adoption of novel technologies and anatomical techniques, surgical management of benign prostatic hyperplasia (BPH) provides significant benefits in terms of obstruction relief, early urethral catheter removal, and faster return to daily activities. However, the main pitfall of BPH surgery in sexually active men remains ejaculatory dysfunction (EjD), which permanently affects quality of life.

Objective: To detail a novel technique for marking the intraprostatic urethra through a retrograde injection of indocyanine green to enhance selective dissection of prostatic lobes during urethra-sparing robot-assisted simple prostatectomy (US-RASP) with the use of near-infrared fluorescence imaging (NIFI). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183095
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http://dx.doi.org/10.1016/j.eururo.2018.11.051DOI Listing
March 2019
14 Reads

Pelvic magnetic resonance imaging parameters predict urinary incontinence after robot-assisted radical prostatectomy.

Low Urin Tract Symptoms 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Objective: Urinary incontinence (UI) is a major prostate cancer (PCa) treatment-related morbidity. It has been reported that post-prostatectomy UI is related to the width of the pelvic floor muscles (PFM) and the length of the urethra. However, the details of these anatomical parameters are unknown. Read More

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http://dx.doi.org/10.1111/luts.12245DOI Listing
December 2018

Prostatic Urethral Lift (PUL) for obstructive median lobes: 12 month results of the MedLift Study.

Prostate Cancer Prostatic Dis 2018 Dec 12. Epub 2018 Dec 12.

Urology of Virginia, PLLC 225 Clearfield Ave, Virginia Beach, VA, 23462, USA.

Evidence indicating Prostatic Urethral Lift (PUL) delivers significant improvement in symptomatic BPH with low morbidity is based on subjects with lateral lobe (LL) enlargement only. MedLift was an FDA IDE extension of the L.I. Read More

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http://dx.doi.org/10.1038/s41391-018-0118-xDOI Listing
December 2018

Institutional patient accrual volume and the treatment quality of I‑125 prostate seed implantation in a Japanese nationwide prospective cohort study.

Strahlenther Onkol 2018 Dec 5. Epub 2018 Dec 5.

Japanese Foundation for Prostate Research, Tokyo, Japan.

Purpose: It is unclear whether experience at high-volume institute improves the treatment quality of prostate seed implantation. The aim of this study was to evaluate the effect of institutional experience on postimplant dosimetric parameters in a nationwide prospective cohort study.

Methods: From July 2005 to June 2007, 2354 patients were registered in the Japanese Prostate Cancer Outcome Study of Permanent I‑125 Seed Implantation (J-POPS), and 1126 patients treated with seed implantation alone were evaluated. Read More

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http://link.springer.com/10.1007/s00066-018-1407-y
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http://dx.doi.org/10.1007/s00066-018-1407-yDOI Listing
December 2018
7 Reads

Use of rectal mucosal grafts in substitution urethroplasty: an early series.

Transl Androl Urol 2018 Dec;7(6):907-911

1Department of Urology, 2Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

Background: To evaluate the feasibility of use of rectal mucosal grafts for augmentation urethroplasty.

Methods: A series of five patients who underwent rectal mucosal graft urethroplasty for urethral stricture disease were identified. Descriptive statistics were used to describe these patients. Read More

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http://tau.amegroups.com/article/view/22220/21689
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http://dx.doi.org/10.21037/tau.2018.10.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256045PMC
December 2018
8 Reads

Posterior, Anterior, and Periurethral Surgical Reconstruction of Urinary Continence Mechanisms in Robot-assisted Radical Prostatectomy: A Description and Video Compilation of Commonly Performed Surgical Techniques.

Eur Urol 2018 Dec 2. Epub 2018 Dec 2.

VU University Medical Center, Amsterdam, The Netherlands.

Background: Robot-assisted radical prostatectomy (RARP) is hampered by side effects that may have a serious impact on quality of life, particularly stress urinary incontinence. Continence rates may be improved by surgical reconstruction of the pelvic floor.

Objective: Video illustrations of different surgical techniques may be particularly worthwhile for practicing urologists in understanding the pelvic-floor anatomy and in the training of residents and fellows in urology. Read More

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http://dx.doi.org/10.1016/j.eururo.2018.11.035DOI Listing
December 2018
7 Reads

Primary urethral squamous cell carcinoma: a unique manifestation of a penile tumor.

J Int Med Res 2019 Feb 5;47(2):999-1004. Epub 2018 Dec 5.

1 Department of Urology, Cantonal Hospital Aarau, Aarau, Switzerland.

This case report describes a unique manifestation of a primary urethral squamous cell carcinoma (SCC) as the underlying pathology in an 80-year-old male patient who underwent partial penectomy due to an enlarging penile mass. Persistent pain in the right knee was discovered to be a pathologic fracture using magnetic resonance imaging. Computed tomography-guided biopsy confirmed metastatic SCC. Read More

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http://dx.doi.org/10.1177/0300060518813506DOI Listing
February 2019
2 Reads

Radiotherapy of prostate cancer in renal transplant recipients: single-center experience.

Neoplasma 2019 Jan 4;66(1):155-159. Epub 2018 Sep 4.

Department of Urology with Kidney Transplant Center, Comenius University Faculty of Medicine and University Hospital Bratislava, Bratislava, Slovakia.

This study analyzed the long-term outcomes of localized prostate cancer in renal transplant recipients after radiotherapy treatment - mainly brachytherapy. We retrospectively analyzed clinical data of renal transplant recipients between 2003 and 2016 at a single tertiary center, and identified four patients with high serum PSA level during regular follow-up, 1-108 months after primary renal transplantation. The mean age of patients with detected high serum PSA level with 9. Read More

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http://www.elis.sk/index.php?page=shop.product_details&f
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http://dx.doi.org/10.4149/neo_2018_180507N298DOI Listing
January 2019
16 Reads

[Enrico Bottini (1835-1903), Italian Physician and Politician: A Master of Antisepsis and a Pioneer of Modern Surgery].

Acta Med Hist Adriat 2018 12;16(2):293-302

Università di Genova, Genova, Italia

Enrico Bottini (Stradella, Pavia, 7 September 1835 - Porto Maurizio, Sanremo, 11 March 1903) was a multifaceted surgeon, who left a strong mark in modern surgery, not only Italian but worldwide. A pupil of Porta and Ribeti, as well as the distinguished French surgeon and anatomist Charles-Marie-Édouard Chassaignac, he has dedicated himself throughout his career to various areas of medicine, ranging from bacteriology and anti-sepsis (use of a derivative of phenic acid) to urological surgery (the so-called "endo-urethral galva-cauterization", also called Bottini's operation, or Perineal incision according to Bottini). He has also successfully dedicated himself to gynecology (trans-vaginal hysterectomy for uterine cancer and surgical treatment of vesicovaginal fistulas), maxillofacial surgery (endo-oral resection of the maxilla, subperiosteal resection of the mandible for the treatment of the stable jaw, total amputation of the larynx and the tongue for carcinomas), the dermosurgery (use of the electrocautery), and the vascular surgery (resection of the inferior vena cava). Read More

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December 2018
1 Read

Injection of Urethral Bulking Agents.

Urol Clin North Am 2019 Feb;46(1):1-15

Urinary Tract and Pelvic Reconstruction, Department of Urology, MD Anderson Cancer Center, Unit 1373, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address:

Urethral injection is a safe and minimally invasive method of treating female stress urinary incontinence with multiple bulking agents currently commercially available. Although there are numerous studies that demonstrate efficacy, long-term success is not yet proven. This article aims to describe the mechanism of action and properties of various agents, patient selection factors, available techniques for injection, outcomes of urethral injections, and complications associated with the procedure. Read More

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http://dx.doi.org/10.1016/j.ucl.2018.08.012DOI Listing
February 2019
12 Reads

Transobturator Advance® Sling Suspension for the Treatment of Postprostatectomy Stress Urinary Incontinence.

Acta Clin Croat 2018 Jun;57(Suppl 1):77-84

Department of Urology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Stress urinary incontinence (SUI) continues to present a major complication after radical prostatectomy. Suburethral slings represent one of the less invasive options for postprostatectomy SUI, and a more recent addition is a transobturator sling, the AdVance®. We report our results with the AdVance® sling for the management of postoperative SUI. Read More

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http://dx.doi.org/10.20471/acc.2018.57.s1.12DOI Listing
June 2018
12 Reads

Evaluation of tumor coverage after MR-guided prostate focal laser ablation therapy.

Med Phys 2019 Feb 7;46(2):800-810. Epub 2018 Dec 7.

Robarts Research Institute, Western University, London, ON, N6A 5B7, Canada.

Purpose: Prostate cancer is the most common noncutaneous cancer among men in the USA. Focal laser thermal ablation (FLA) has the potential to control small tumors while preserving urinary and erectile function by leaving the neurovascular bundles and urethral sphincters intact. Accurate needle guidance is critical to the success of FLA. Read More

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http://doi.wiley.com/10.1002/mp.13292
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http://dx.doi.org/10.1002/mp.13292DOI Listing
February 2019
10 Reads

The role of inguinal lymph node dissection in men with urethral squamous cell carcinoma.

Urol Oncol 2018 12 13;36(12):526.e1-526.e6. Epub 2018 Nov 13.

Department of Surgery, Section of Urology, The University of Chicago, Chicago, IL.

Introduction: Urethral squamous cell cancer is a rare disease with limited clinical recommendations regarding management of the inguinal lymph nodes. Despite the similarities to penile cancer in terms of squamous cell carcinoma (SCC) histology and lymphatic drainage, there is not enough evidence to recommend for or against a prophylactic inguinal lymph node dissection (ILND) in patients with clinically negative groins and a primary tumor stage of T1b or higher. The objective of the study was to identify the rate of prophylactic inguinal lymph node dissection, node positive rate, and overall survival in patients with clinical T1 to T4 stage. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10781439183035
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http://dx.doi.org/10.1016/j.urolonc.2018.09.014DOI Listing
December 2018
11 Reads

Appropriate preoperative membranous urethral length predicts recovery of urinary continence after robot-assisted laparoscopic prostatectomy.

World J Surg Oncol 2018 Nov 16;16(1):224. Epub 2018 Nov 16.

Department of Urology, Iwate Medical University School of Medicine, 19-1, Uchimaru, Morioka-shi, Iwate, 020-8505, Japan.

Purpose: We investigated that preoperative membranous urethral length (MUL) would be associated with the recovery of urinary continence after robot-assisted laparoscopic prostatectomy (RALP).

Patients And Methods: We studied 204 patients who underwent RALP between May 2013 and March 2016. All patients underwent pelvic magnetic resonance imaging (MRI) preoperatively to measure MUL. Read More

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http://dx.doi.org/10.1186/s12957-018-1523-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240250PMC
November 2018
7 Reads

Preoperative magnetic resonance imaging in predicting early continence recovery after robotic radical prostatectomy.

Actas Urol Esp 2018 Nov 9. Epub 2018 Nov 9.

Departamento de Urología, Hospital Universitari Vall d' Hebron, Universitat Autonoma de Barcelona, Barcelona, España.

Introduction And Aims: Urinary incontinence is a common complication after radical prostatectomy. The aim of our study was to describe the preoperative anatomical features using magnetic resonance imaging in order to predict early continence recovery after robotic radical prostatectomy.

Material And Methods: 72 patients who underwent robotic radical prostatectomy were prospectively analysed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02104806183019
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http://dx.doi.org/10.1016/j.acuro.2018.07.003DOI Listing
November 2018
9 Reads

Integrated treatment for autonomic paraneoplastic syndrome improves performance status in a patient with small lung cell carcinoma: a case report.

BMC Neurol 2018 Nov 10;18(1):189. Epub 2018 Nov 10.

Department of Neurology, Aomori Prefectural Central Hospital, 2-1-1 Higashi-Tsukurimichi, Aomori, 030-8551, Japan.

Background: Paraneoplastic neurological syndromes (PNS) are rare disorders associated with cancer and are believed to be immune mediated. Patients with autonomic PNS suffer from variable combinations of parasympathetic and sympathetic failure. Autonomic PNS are usually associated with other PNS, such as encephalomyelitis and sensory neuropathy; however, autonomic symptoms may rarely manifest as PNS symptoms. Read More

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
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http://dx.doi.org/10.1186/s12883-018-1192-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230283PMC
November 2018
17 Reads

Early Catheter Removal After Robot-assisted Radical Prostatectomy: Results from a Prospective Single-institutional Randomized Trial (Ripreca Study).

Eur Urol Focus 2018 Nov 6. Epub 2018 Nov 6.

Urology, Humanitas Clinical and Research Hospital, Rozzano, Milan, Italy.

Background: The adoption of robotic technology in the treatment of prostate cancer (PCa) could lead to improvement in outcomes.

Objective: To evaluate feasibility, to compare functional outcomes, and to assess the economic benefits of removing catheter on the postoperative day (POD) 3 versus POD 5 after robot-assisted radical prostatectomy (RARP).

Design, Setting, And Participants: From September 2016 to May 2017, patients selected to undergo RARP for clinically localized PCa at a high-volume center were prospectively randomized into group 1 (POD 3; n=72) versus group 2 (POD 5, n=74). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24054569183031
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http://dx.doi.org/10.1016/j.euf.2018.10.013DOI Listing
November 2018
10 Reads

A prospective audit of the 10-year outcomes from low dose-rate brachytherapy for early stage prostate cancer.

N Z Med J 2018 Nov 9;131(1485):13-18. Epub 2018 Nov 9.

Statistician, School of Mathematics and Statistics, Victoria University, Wellington.

Aim: New Zealand men diagnosed with early stage prostate cancer need to know what outcomes to expect from management options.

Methods: Between 2001 and 2016, 951 men were treated with low dose-rate brachytherapy (permanent iodine-125 seed implantation) by the Wellington Prostate Brachytherapy Group based at Southern Cross Hospital, Wellington. At follow up after treatment, men had their PSA measured and were scored for urinary, bowel and sexual side effects. Read More

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November 2018
4 Reads

Cytoreductive and Palliative Radical Prostatectomy, Extended Lymphadenectomy and Bilateral Orchiectomy in Advanced Prostate Cancer with Oligo and Widespread Bone Metastases: Result of a Feasibility, Our Initial Experience.

Urol J 2018 Nov 3. Epub 2018 Nov 3.

Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, 9th Boostan, Pasdaran avenue, Tehran, Iran.

Purpose: to evaluate the feasibility of cytoreductive radical prostatectomy (RP), lymphadenectomy, and bilateral orchiectomy in patients with advanced prostate cancer (PCa) with oligo- and poly-metastases. Furthermore, the functional and oncological outcomes of these patients in comparison with the control group that underwent treatment only with systemic therapy (ST group) is investigated in a well-selected, prospective cohort study.   Material and methods: A total of 26 patients were enrolled in CRP (cytoreductive radical prostatectomy) group and 23 patients in ST group. Read More

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http://dx.doi.org/10.22037/uj.v0i0.4783DOI Listing
November 2018
9 Reads

Second-generation of temporary implantable nitinol device for the relief of lower urinary tract symptoms due to benign prostatic hyperplasia: results of a prospective, multicentre study at 1 year of follow-up.

BJU Int 2018 Nov 1. Epub 2018 Nov 1.

Division of Urology, Frimley Health, London, UK.

Objectives: To report the clinical experience with a second-generation of temporary implantable nitinol device (iTIND; Medi-Tate Ltd, Or-Akiva, Israel) for the treatment of lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) after 1 year of follow-up.

Patients And Methods: In all, 81 patients with LUTS, International Prostate Symptom Score (IPSS) ≥10, maximum urinary flow rate (Q ) ≤12 mL/s, and prostate volume <75 mL, were enrolled in this prospective Research Ethics Committee-approved multicentre study. The main exclusion criteria were: haemostatic disorders, post-void residual urine volume (PVR) >250 mL, obstructive median lobe, and previous prostate surgery. Read More

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http://dx.doi.org/10.1111/bju.14608DOI Listing
November 2018
2 Reads

May perioperative ultrasound-guided pelvic floor muscle training promote early recovery of urinary continence after robot-assisted radical prostatectomy?

Neurourol Urodyn 2019 Jan 30;38(1):158-164. Epub 2018 Oct 30.

Global Nursing Research Center, The University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Aims: The efficacy of perioperative pelvic floor muscle training (PFMT) for continence recovery after robot-assisted radical prostatectomy (RARP) remains unclear. Visualization of the bladder neck and urethra using transperineal ultrasound (US) may promote self-recognition of urethral closure during PFM contraction. This study aimed to examine whether transperineal US-guided PFMT promotes early recovery of post-RARP incontinence. Read More

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http://doi.wiley.com/10.1002/nau.23811
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http://dx.doi.org/10.1002/nau.23811DOI Listing
January 2019
27 Reads

Metastatic primary urothelial carcinoma of the prostatic urethra: A case report.

Urologia 2018 Oct 30:391560318808631. Epub 2018 Oct 30.

Tepecik Training and Research Hospital, İzmir, Turkey.

Introduction:: Primary carcinomas of the urethra differ by location and histologic subtype. Primary urethral cancer of the proximal urethra is rare and aggressive tumor with a high propensity for regional and distant metastases.

Case Description:: In this case report, we present primary urothelial carcinoma of the prostatic urethra, diagnosed by transrectal ultrasound-guided biopsy of the prostate and having multiple metastases at the time of diagnosis. Read More

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http://dx.doi.org/10.1177/0391560318808631DOI Listing
October 2018

[French ccAFU guidelines - Update 2018-2020: Bladder cancer].

Prog Urol 2018 Nov 23;28(12S):S46-S78. Epub 2018 Oct 23.

Comité de cancérologie de l'Association française d'urologie, groupe vessie, maison de l'urologie, 11, rue Viète, 75017 Paris, France; Service d'urologie, hôpital européen Georges-Pompidou, université Paris Descartes, AP-HP, 75015 Paris, France.

Objective: To propose updated French guidelines for non-muscle invasive (NMIBC) and muscle-invasive (MIBC) bladder cancers.

Methods: A Medline search was achieved between 2015 and 2018, as regards diagnosis, options of treatment and follow-up of bladder cancer, to evaluate different references with levels of evidence.

Results: Diagnosis of NMIBC (Ta, T1, CIS) is based on a complete deep resection of the tumor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S11667087183046
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http://dx.doi.org/10.1016/j.purol.2018.07.283DOI Listing
November 2018
27 Reads

Renocolic fistula secondary to curative intent extended field radiotherapy for cervical cancer.

Gynecol Oncol Rep 2018 Nov 11;26:66-68. Epub 2018 Oct 11.

Division of Gynecologic Oncology, St. Luke's University Health Network, 701 Ostrum Street, Bethlehem, PA 18015, USA.

•Renocolic fistula is a rare complication from extended field radiation.•Pathogenesis may involve colonic mucosal ischemia from radiation-induced colitis.•Conservative management with urethral stenting can result in complete resolution. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23525789183009
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http://dx.doi.org/10.1016/j.gore.2018.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197436PMC
November 2018
9 Reads

Predictors of persistent stress urinary incontinence after transvaginal mesh repair.

BMC Womens Health 2018 Oct 25;18(1):174. Epub 2018 Oct 25.

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, 13-1, Takaramachi, Kanazawa, Ishikawa, 920-8641, Japan.

Background: We evaluated the effect of transvaginal mesh (TVM) surgery for voiding function and continence using noninvasive examination and questionnaire. The present study aimed to ascertain which categories of patients need concomitant mid-urethral sling (MUS) after TVM surgery.

Methods: We included women who underwent TVM procedure between November 2009 and October 2013. Read More

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https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12905-018-0667-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202820PMC
October 2018
4 Reads

Experts vs super-experts: differences in automated performance metrics and clinical outcomes for robot-assisted radical prostatectomy.

BJU Int 2018 Oct 25. Epub 2018 Oct 25.

Center for Robotic Simulation and Education, Catherine and Joseph Aresty Department of Urology, USC Institute of Urology, University of Southern California, Los Angeles, CA, USA.

Objectives: To evaluate automated performance metrics (APMs) and clinical data of experts and super-experts for four cardinal steps of robot-assisted radical prostatectomy (RARP): bladder neck dissection; pedicle dissection; prostate apex dissection; and vesico-urethral anastomosis.

Subjects And Methods: We captured APMs (motion tracking and system events data) and synchronized surgical video during RARP. APMs were compared between two experience levels: experts (100-750 cases) and super-experts (2100-3500 cases). Read More

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http://doi.wiley.com/10.1111/bju.14599
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http://dx.doi.org/10.1111/bju.14599DOI Listing
October 2018
11 Reads

BGJ398, A Pan-FGFR Inhibitor, Overcomes Paclitaxel Resistance in Urothelial Carcinoma with FGFR1 Overexpression.

Int J Mol Sci 2018 Oct 15;19(10). Epub 2018 Oct 15.

Division of Medical Oncology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Korea.

Paclitaxel (PTX) is commonly used to treat urothelial carcinoma (UC) after platinum-based chemotherapy has failed. However, single-agent taxane therapy is not sufficient to inhibit tumor progression and drug resistance in advanced UC. Epithelial-to-mesenchymal transition (EMT) induced by fibroblast growth factor receptor ()1 signaling has been proposed as a mechanism of PTX resistance, but it is unclear whether this can be overcome by inhibition. Read More

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http://www.mdpi.com/1422-0067/19/10/3164
Publisher Site
http://dx.doi.org/10.3390/ijms19103164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214101PMC
October 2018
3 Reads

Artificial sphincter "BR - SL - AS 904" in the treatment of urinary incontinence after radical prostatectomy: efficacy, practicality and safety in a prospective and multicenter study.

Int Braz J Urol 2018 Nov-Dec;44(6):1215-1223

Disciplina de Urologia, Unesp - Universidade Estadual Paulista, São Paulo, SP, Brasil.

Purpose: The objective of the present study is to test the efficiency and practicality of a new artificial sphincter "BR - SL - AS - 904" in the control of urinary incontinence in post - PR patients and to evaluate their complications.

Patients And Methods: Fifteen patients with incontinence after one year of radical prostatectomy were included prospectively. All patients underwent artificial urethral sphincter (AUS) implant "BR - SL - AS - 904" according to established technique. Read More

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http://dx.doi.org/10.1590/S1677-5538.IBJU.2018.0128DOI Listing
March 2018
5 Reads

Management of Urethritis: Is It Still the Time for Empirical Antibiotic Treatments?

Eur Urol Focus 2019 01 11;5(1):29-35. Epub 2018 Oct 11.

Alta Uro AG, Merian Iselin Klinik, Center of Biomechanics & Calorimetry (COB), University of Basel, Basel, Switzerland.

Context: Urethritis prevalence in Europe changed in the last years due to both the increase of migratory streams from North Africa and the more frequent exposition of males to relevant risk factors. Owing to these reasons, urethritis treatment should be optimized by accurate microbiological investigations to avoid the risk of persistence, recurrence, or reinfection.

Objective: The aim of this systematic review is to optimize the treatments for urethritis and investigate the applicability of nucleic acid amplification test (NAAT) as the primary microbiological investigation. Read More

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http://dx.doi.org/10.1016/j.euf.2018.10.006DOI Listing
January 2019
3 Reads

Condyloma Acuminata of the Urethra in a Male Renal Transplant Recipient: A Case Report.

Transplant Proc 2018 Oct 20;50(8):2553-2557. Epub 2018 Mar 20.

Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; Department of Advanced Transplant and Regenerative Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.

Background: Condyloma acuminatum (CA) is a common sexually transmitted disease associated with human papilloma virus (HPV). CA occurring in the urethra is rare and has not been reported in male renal transplant recipients. In addition, despite immunosuppressive conditions and increased risk of HPV-related malignant neoplasms in transplant recipients, HPV testing in male transplant recipients has been uncommon. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183044
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http://dx.doi.org/10.1016/j.transproceed.2018.02.182DOI Listing
October 2018
7 Reads