5,959 results match your criteria Urethral Cancer


Radical cystectomy and W-shaped ileal orthotopic neobladder reconstruction with serosa-lined tunneled ureteroileal anastomoses: A critical analysis of the short-term voiding patterns and urodynamic and functional outcomes.

Indian J Urol 2019 Apr-Jun;35(2):121-128

Department of Urology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Introduction: We present the short-term voiding patterns and functional and urodynamic outcomes of W-shaped ileal orthotopic neobladder (ONB) following radical cystectomy (RC).

Materials And Methods: Forty-one patients who underwent RC and W-shaped ONB creation between July 2015 and January 2018 were enrolled. Data were analyzed in terms of voiding patterns, urodynamic findings, and functional outcomes at 6 months after surgery. Read More

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http://dx.doi.org/10.4103/iju.IJU_356_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458799PMC

Lymph node yield, survival benefit, and safety of high and low ligation of the inferior mesenteric artery in colorectal cancer surgery: a systematic review and meta-analysis.

Int J Colorectal Dis 2019 Apr 17. Epub 2019 Apr 17.

Department of General Surgery, Gansu Provincial Hospital, Donggang West Road, Lanzhou, 730000, People's Republic of China.

Purpose: The aim of this meta-analysis was to compare high inferior mesenteric artery (IMA) ligation (HL) with low IMA ligation (LL) for the treatment of colorectal cancer and to evaluate the lymph node yield, survival benefit, and safety of these surgeries.

Methods: PubMed, Embase, Cochrane Library, Web of Science, and China Biomedical Literature Database (CBM) were systematically searched for relevant articles that compared HL and LL for sigmoid or rectal cancer. We calculated the odds ratio (OR) with 95% confidence intervals (CIs) for dichotomous outcomes and the weighted mean difference (WMD) for continuous outcomes. Read More

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http://dx.doi.org/10.1007/s00384-019-03291-5DOI Listing
April 2019
1 Read

Role of MRI in planning radical prostatectomy: what is the added value?

World J Urol 2019 Apr 15. Epub 2019 Apr 15.

University College London Hospital, NHS Foundation Trust, 47 Wimpole Street, Marylebone, London, W1G 8SE, UK.

Introduction: The goal of radical prostatectomy is to eradicate oncological disease while achieving the best possible functional outcomes. In this regard, nerve sparing offers a greater chance of recovering potency after surgery. Accurately locating prostate cancer foci is instrumental for identifying good candidates for this approach whilst maintaining safe oncological margins. Read More

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http://dx.doi.org/10.1007/s00345-019-02762-2DOI Listing

Use of a linear stapler for urethral and dorsal vein complex transection during laparoscopic total pelvic exenteration in rectal cancer.

Tech Coloproctol 2019 Apr 15. Epub 2019 Apr 15.

Department of Gastrointestinal Surgery, Faculty of Medicine, Kagawa University, Miki-cho, Kagawa, Japan.

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http://link.springer.com/10.1007/s10151-019-01974-3
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http://dx.doi.org/10.1007/s10151-019-01974-3DOI Listing
April 2019
2 Reads

Robotic-assisted perineal versus transperitoneal radical prostatectomy: A matched-pair analysis.

Turk J Urol 2019 Apr 3. Epub 2019 Apr 3.

Department of Urology, Health Sciences University, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.

Objective: We compared the outcomes of robotic-assisted radical perineal prostatectomy (r-PRP) versus robotic-assisted transperitoneal laparoscopic radical prostatectomy (RARP).

Material And Methods: Between November 2016 and September 2017 in our center, 40 patients underwent r-PRP, and 40 patients underwent RARP. All patients also underwent multiparametric magnetic resonance imaging (mpMRI) to exclude the cases with locally advanced disease. Read More

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http://dx.doi.org/10.5152/tud.2019.98254DOI Listing
April 2019
1 Read

Genital-Sparing Cystectomy versus Standard Urethral-Sparing Cystectomy Followed with Orthotopic Neobladder in Women with Bladder Cancer: Incidence and Causes of Hypercontinence with an Ultrastructure Study of Urethral Smooth Muscles.

Open Access Maced J Med Sci 2019 Mar 27;7(6):978-981. Epub 2019 Mar 27.

Department of Urology, Theodor Bilharz Research Institute, Cairo, Egypt.

Background: Bladder cancer in women is an indication for radical cystectomy (RC) when the tumour is confined muscle-invasive bladder cancer (MIBC) of T2 N0M0, or high risk progressive non-muscle invasive bladder cancer (NMIBC). Radical cystectomy is either genital-sparing cystectomy (GSC) or standard urethra-sparing cystectomy (USC) that is followed with orthotopic ileal neobladder (ONB). Post-operative chronic retention "Hypercontinence" had been reported in different series following URS or GSC and ONB. Read More

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http://dx.doi.org/10.3889/oamjms.2019.206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454182PMC
March 2019
1 Read

[Robot-assisted radical prostatectomy. Functional result. Part I. (in Russian only)].

Khirurgiia (Mosk) 2019 (3):111-120

Chair of Urology, Evdokimov Moscow State University of Medicine and Dentistry of Ministry of Health of the Russia, Moscow, Russia.

Robot-assisted operations as widely used in urology, gynecology, general and cardiovascular surgery are considered by many experts as a new 'gold standard' of surgical treatment of various diseases in developed countries. Robot-assisted radical prostatectomy for prostate cancer is the most common robotic procedure. Better functional outcomes of robot-assisted radical prostatectomy are due to another (new) understanding of pelvic surgical anatomy, new approach implying dissection and preservation of external urethral sphincter and neurovascular structures. Read More

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http://dx.doi.org/10.17116/hirurgia2019031111DOI Listing
January 2019
1 Read

A Case of Metastatic Prostate Cancer to the Urethra that Resolved after Androgen Deprivation Therapy.

Urology 2019 Mar 29. Epub 2019 Mar 29.

Department of Urology, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH.

An 83 year-old male with Gleason score 4+3 prostatic adenocarcinoma status post brachytherapy developed obstructive voiding symptoms nine years after brachytherapy. PSA was 0.67. Read More

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http://dx.doi.org/10.1016/j.urology.2019.03.022DOI Listing

[Short-term outcomes of robot-assisted transanal total mesorectal excision].

Zhonghua Wei Chang Wai Ke Za Zhi 2019 Mar;22(3):267-272

Department of General Surgery, Daping Hospital, Army Medical university, Chongqing 400042, China, Email:

Objective: To explore the feasibility and safety of Da Vinci robot-assisted transanal total mesorectal excision (taTME).

Methods: From May 2017 to July 2018, six rectal cancer patients underwent Da Vinci robot-assisted taTME at our hospital. The clinical data and short-term follow-up results were retrospectively analyzed. Read More

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March 2019
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Improving rectal dosimetry for patients with intermediate and high-risk prostate cancer undergoing combined high-dose-rate brachytherapy and external beam radiotherapy with hydrogel space.

J Contemp Brachytherapy 2019 Feb 28;11(1):8-13. Epub 2019 Feb 28.

The Austin Hospital, Heidelberg, Australia.

Purpose: To report on rectal dosimetric and toxicity outcomes of intermediate and high-risk prostate cancer patients undergoing combined high-dose-rate (HDR) brachytherapy and external beam radiotherapy (EBRT) with or without hydrogel spacer (HS) insertion.

Material And Methods: A total of 97 patients were analyzed in this study, with 32 patients (33%) who had HS insertion compared with a preceding group of 65 patients (67%) without HS. HS safety, the dosimetric effects on organs at risk (rectal, urethral, penile bulb, and bladder) as well as gastrointestinal (GI) and genitourinary toxicity were evaluated and compared between the two groups. Read More

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http://dx.doi.org/10.5114/jcb.2019.82836DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431099PMC
February 2019
1 Read

Hyaluronic gel injection into the vesicovaginal septum for high-dose-rate brachytherapy of uterine cervical cancer: an effective approach for bladder dose reduction.

J Contemp Brachytherapy 2019 Feb 29;11(1):1-7. Epub 2019 Jan 29.

Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.

Purpose: The purpose of this study was to report our initial experience of hyaluronic acid gel injection (HGI) in the vesicovaginal septum (VVS) for bladder dose reduction in brachytherapy (BT) for uterine cervical carcinoma.

Material And Methods: Between September 2016 and May 2018, 15 uterine cervical cancer patients received HGI in the VVS as a part of their definitive radiotherapy (RT) treatment consisting of external beam radiation therapy (EBRT) with additional BT. Of those, 9 patients received BT both with and without HGI, and remaining 6 patients were excluded because these 6 patients received HGI in the VVS for all BT fractions. Read More

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http://dx.doi.org/10.5114/jcb.2019.82612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431109PMC
February 2019
2 Reads

Impact of α-adrenoceptor antagonists on prostate cancer development, progression and prevention.

Am J Clin Exp Urol 2019 18;7(1):46-60. Epub 2019 Feb 18.

Department of Urology, University of Kentucky College of Medicine Lexington, Kentucky 40536, USA.

Two decades following the discovery that α1-adrenoceptor antagonists suppress prostate tumor growth at the molecular and cellular level, the impact of α-blockade as re-purposed treatment strategy in the medical management of prostate cancer is gradually being recognized. Prostate cancer is the second most common cause of cancer deaths among males in the United States, yet the disease maintains inconsistent recommendations for prevention and screening. The functional relationship between α-adrenergic signaling and smooth muscle cells in the stroma of the prostate gland and the bladder neck empowered the use of α-adrenoceptor antagonists for the relief of urethral obstruction and clinical symptoms associated with benign prostatic hyperplasia (BPH). Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420703PMC
February 2019
1 Read

Modified U-Shaped ileal neobladder designed for facilitating neobladder-urethral anastomosis in extracorporeal reconstruction after robotic-assisted radical cystectomy.

J Cancer Res Ther 2019 Mar;15(Supplement):S51-S55

Department of Urology, Shuang Ho Hospital, New Taipei City; Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Background/objective: To report the initial experience and the early outcomes of a modified U-shaped ileal neobladder, which was developed to facilitate the neobladder-urethral anastomosis by minimizing the anastomotic tension.

Patients And Methods: Between June 2015 and December 2016, two male and two female patients (median age: 65.5 years, range: 43-72 years) underwent the modified U-shaped ileal neobladder after robotic-assisted radical cystectomy (RARC). Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_538_17DOI Listing
March 2019
2 Reads

Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography.

Biomed Opt Express 2019 Mar 22;10(3):1405-1419. Epub 2019 Feb 22.

Department of Electrical and Computer Engineering, Boston University, 8 St. Mary's Street, Boston, MA 02215, USA.

Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom. Read More

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http://dx.doi.org/10.1364/BOE.10.001405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420282PMC
March 2019
1 Read

Rectum-spacer related acute toxicity - endoscopy results of 403 prostate cancer patients after implantation of gel or balloon spacers.

Radiat Oncol 2019 Mar 15;14(1):47. Epub 2019 Mar 15.

Dapartment of Radiotherapy and Radio-Oncology, LKH Salzburg University Clinics, Paracelsus Medical University, Müllner Hauptstraße 48, 5020, Salzburg, Austria.

Background: Rectal spacers are used to limit dose to the anterior rectal wall in high dose external beam radiation therapy of the prostate and have been shown to reduce radiation induced toxicity. Here we report the complication rate and toxicity of the implantation procedure in a large cohort of patients who have either received a gel- or balloon-type spacer.

Methods: In total, 403 patients received rectal spacing, 264 with balloon, 139 with gel. Read More

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http://dx.doi.org/10.1186/s13014-019-1248-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419822PMC
March 2019
1 Read

Multi-Institutional Outcomes of Minimally Invasive Harvest of Rectal Mucosa Graft for Anterior Urethral Reconstruction.

J Urol 2019 Jan 29:101097JU0000000000000087. Epub 2019 Jan 29.

Department of Urology, Lahey Hospital and Medical Center , Burlington , Massachusetts.

Purpose: We report multi-institutional outcomes in patients who underwent urethroplasty with a rectal mucosa graft.

Materials And Methods: We used the TURNS (Trauma and Urologic Reconstructive Network of Surgeons) database to identify patients who underwent urethral reconstruction with transanal harvest of a rectal mucosa graft. We reviewed preoperative demographics, stricture etiology, previous management and patient outcomes. Read More

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http://www.jurology.com/doi/10.1097/JU.0000000000000087
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http://dx.doi.org/10.1097/JU.0000000000000087DOI Listing
January 2019
4 Reads

Primary Squamous Cell Carcinoma of the Male Proximal Urethra: Outcomes from a Single Centre.

Eur Urol Focus 2019 Mar 7. Epub 2019 Mar 7.

Department of Urology, University College London Hospital, London, UK; NIHR Biomedical Research Centre, University College London Hospital, London, UK; Division of Surgery and Interventional Science, University College London, London, UK. Electronic address:

Background: Primary squamous cell carcinoma (SCC) of the male proximal urethra is an aggressive and rare urogenital malignancy.

Objective: To review the surgical management and outcomes for male proximal urethral SCCs within a single centre and to suggest an algorithm for the surgical management of these rare tumours.

Design, Setting, And Participants: This was a retrospective study of patients undergoing surgery for male proximal urethral SCC within a single tertiary academic centre managing rare genital tumours. Read More

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http://dx.doi.org/10.1016/j.euf.2019.02.016DOI Listing

Prognostic implications of prostatic urethral involvement in non-muscle-invasive bladder cancer.

World J Urol 2019 Mar 8. Epub 2019 Mar 8.

James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Baltimore, MD, 21287, USA.

Purpose: Non-muscle-invasive bladder cancer involving the prostatic urethra is associated with pathologic upstaging and shorter survival. We investigated the survival impact of prostatic urethral involvement in non-muscle-invasive patients who are not upstaged at cystectomy.

Methods: From 2000 to 2016, 177 male patients underwent cystectomy for high-risk non-muscle-invasive bladder cancer and remained pT1, pTis, or pTa, and N0 on final pathology; 63 (35. Read More

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http://dx.doi.org/10.1007/s00345-019-02673-2DOI Listing
March 2019
2 Reads

Reirradiation of Locally Recurrent Prostate Cancer With Volumetric Modulated Arc Therapy.

Int J Radiat Oncol Biol Phys 2019 Feb 27. Epub 2019 Feb 27.

Department of Radiotherapy and Radiosurgery, Humanitas Clinical and Research Center, Humanitas University, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.

Purpose: This study explores the efficacy and safety of reirradiation with modern radiation therapy techniques in patients previously irradiated for prostate cancer and affected by local relapse of disease.

Methods And Materials: Patients affected by previously irradiated prostate cancer were enrolled in this reirradiation study if they had a biochemical relapse and a C-choline positron emission tomography scan revealing the presence of a local recurrence of disease. Reirradiation consisted of a stereotactic treatment delivered by image guided radiation therapy-volumetric modulated arc therapy with flattening filter-free technology in 5 daily fractions. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.041DOI Listing
February 2019
2 Reads

Revisiting Vesico-urethral anastomosis during open radical retropubic prostatectomy, simple and reproducible technique, a single center experience with 200 cases.

Urol J 2019 02 26. Epub 2019 Feb 26.

Department of Urology, Erfan Hospital, Tehran, Iran.

Introduction: Vesico-urethral anastomosis (VUA) represents a challenging step of Open Radical Prostatectomy (ORP) because of limitation of space in the depth of men's pelvis, lack of control on knots during tightening and subsequent inadequate coupling of VUA or breakdown of knots and extremely difficult reapplication of sutures. To facilitate this step of RP we have developed a simple and reproducible technique and report our 8 years' experience.

Technique: We used two extra-long DeBakey tissue forceps to approximate the bladder neck to the urethral stump. Read More

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http://dx.doi.org/10.22037/uj.v0i0.4800DOI Listing
February 2019
1 Read

Uroflow stop test with electromyography: a novel index of urinary continence recovery after RARP.

Int Urol Nephrol 2019 Apr 23;51(4):609-615. Epub 2019 Feb 23.

Division of Urology Clinic, Department of Surgical and Biomedical Sciences, University Hospital of Perugia, Perugia, Italy.

Purpose: Urinary incontinence (UI) is one of the most bothersome surgical side effects after robot-assisted radical prostatectomy (RARP). Alteration of both smooth and striate urethral sphincter occurs after RARP. Since the contraction of perineal muscles is involved in the complex mechanism of urinary continence, the uroflow stop test (UST) seems to predict early continence recovery after RARP. Read More

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http://dx.doi.org/10.1007/s11255-019-02107-3DOI Listing
April 2019
1 Read

Dose to the dominant intraprostatic lesion using HDR vs. LDR monotherapy: A Phase II randomized trial.

Brachytherapy 2019 Feb 19. Epub 2019 Feb 19.

Department of Radiology, Kelowna General Hospital, Kelowna, British Columbia, Canada.

Purpose: To present the dosimetric results of a Phase II randomized trial comparing dose escalation to the MRI-defined dominant intraprostatic lesion (DIL) using either low-dose-rate (LDR) or high-dose-rate (HDR) prostate brachytherapy.

Material And Methods: Patients receiving prostate brachytherapy as monotherapy were randomized to LDR or HDR brachytherapy. Prostate and DILs were contoured on preoperative multiparametric MRI. Read More

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http://dx.doi.org/10.1016/j.brachy.2019.01.006DOI Listing
February 2019
1 Read

Assessment of dose to functional sub-structures in the lower urinary tract in locally advanced cervical cancer radiotherapy.

Phys Med 2019 Mar 13;59:127-132. Epub 2019 Feb 13.

Department of Oncology, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark.

Purpose: To provide an analysis of dose distribution in sub-structures that could be responsible for urinary toxicity after Image-Guided Adaptive BrachyTherapy (IGABT) in Locally Advanced Cervical Cancer (LACC).

Methods: 105 LACC patients treated with radiochemotherapy and IGABT were selected. Sub-structures (bladder wall, trigone, bladder neck, urethra) were contoured on IGABT-planning MRIs. Read More

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http://dx.doi.org/10.1016/j.ejmp.2019.01.017DOI Listing
March 2019
2 Reads

A single-center, prospective, randomized clinical trial to investigate the optimal removal time of the urinary catheter after laparoscopic anterior resection of the rectum: study protocol for a randomized controlled trial.

Trials 2019 Feb 15;20(1):133. Epub 2019 Feb 15.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No.1 Shuai Fu Yuan, Dongcheng District, Beijing, 100730, People's Republic of China.

Background: Urinary catheter placement is essential before laparoscopic anterior resection for rectal cancer. Whether early removal of the catheter increases the incidence of urinary retention and urinary tract infection (UTI) is not clear. This study aims to determine the optimal time for removal of the urinary catheter after laparoscopic anterior resection of the rectum. Read More

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https://trialsjournal.biomedcentral.com/articles/10.1186/s13
Publisher Site
http://dx.doi.org/10.1186/s13063-019-3210-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377729PMC
February 2019
11 Reads
2.117 Impact Factor

[Urodynamics study in patients with urinary incontinence, after surgical treatment of localized prostate cancer].

Urologiia 2018 Dec(6):14-18

MBUZ Clinical and diagnostic Center Zdorovie, Rostov-on-Don, Russia.

Aim: Radical treatment of prostate cancer (PCa) is often associated with the development of urinary incontinence (UI). The etiology of UI after prostatectomy is multifactorial and can be caused by both urethral sphincter deficiency and bladder dysfunction. To date, there are no comparative studies of the development of UI in patients after either organ-preserving treatment or radical prostatectomy (RP). Read More

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December 2018
2 Reads

A Rare Case of Advanced Urethral Diverticular Adenocarcinoma and a Review of Treatment Modalities.

J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619828408

1 Brookdale University Hospitals and Medical Center, New York, NY, USA.

Female urethral diverticular cancer is a very rare entity with only around 100 cases reported so far in literature and accounts for <1% of all malignancies. In this article, we present a 47-year-old African American female with repeated hospital visits for urinary retention, hematuria, and urinary tract infections. Initial computed tomography imaging and cystoscopy was unremarkable except for a distended urinary bladder. Read More

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http://dx.doi.org/10.1177/2324709619828408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376544PMC
February 2019
4 Reads

Malignant lymphoma of the bladder with bilateral hydronephrosis.

Rare Tumors 2019 22;11:2036361318825165. Epub 2019 Jan 22.

Department of Urology, Kurume University School of Medicine, Kurume, Japan.

Lymphoma of the urinary bladder is uncommon, and upper urinary tract obstruction due to lymphoma is rare. Herein, we report a case of malignant lymphoma of the bladder with bilateral hydronephrosis in a 67-year-old female who presented with oliguria. Ultrasonography and computed tomography demonstrated a thickened posterior bladder wall and bilateral hydronephrosis. Read More

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http://dx.doi.org/10.1177/2036361318825165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348503PMC
January 2019
13 Reads

Optimized penile surface mold brachytherapy using latest stereolithography techniques: A single-institution experience.

Brachytherapy 2019 Feb 1. Epub 2019 Feb 1.

University of Toronto, Toronto, Ontario, Canada; Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada. Electronic address:

Purpose: To describe a technique of penile surface mold high-dose-rate (HDR) brachytherapy and early outcomes.

Methods And Materials: Five patients diagnosed with a T1aN0 squamous cell carcinoma of the penis were treated using a penile surface mold HDR brachytherapy technique. A negative impression of the penis was obtained using dental alginate. Read More

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http://dx.doi.org/10.1016/j.brachy.2019.01.002DOI Listing
February 2019
3 Reads
1.987 Impact Factor

Bevacizumab is associated with delayed anastomotic leak after low anterior resection with preoperative radiotherapy for rectal cancer: a case report.

Surg Case Rep 2019 Jan 31;5(1):14. Epub 2019 Jan 31.

Department of Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitamashi, Saitamaken, 330-8503, Japan.

Background: Bevacizumab is an anti-angiogenesis agent used to treat patients with metastatic colorectal cancer and is associated with a variety of complications. We present a patient with rectal cancer who developed a delayed anastomotic leak more than 5 years after undergoing low anterior resection.

Case Report: A 78-year-old man with hematochezia was diagnosed with two synchronous rectal cancers 7 years prior to presentation. Read More

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http://dx.doi.org/10.1186/s40792-019-0573-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357210PMC
January 2019
3 Reads

Positive Precystectomy Biopsies of the Prostatic Urethra or Bladder Neck Do Not Necessarily Preclude Orthotopic Bladder Substitution.

J Urol 2019 Jan 25:101097JU0000000000000034. Epub 2019 Jan 25.

Department of Urology, University Hospital of Bern, University of Bern , Bern , Switzerland.

Purpose: We investigated the influence of positive precystectomy biopsies of the prostatic urethra in males and the bladder neck in females on urethral recurrence, cancer specific and overall survival, and functional outcomes after orthotopic bladder substitution.

Materials And Methods: We retrospectively analyzed the records of 803 consecutive patients, including 703 males and 100 females, who underwent orthotopic bladder substitution as well as precystectomy biopsy of the prostatic urethra in males and the bladder neck in females, at our institution between April 1986 and December 2017.

Results: Precystectomy biopsies were negative in 755 of the 803 patients (94%) (group 1) and positive in 48 (6%) (group 2). Read More

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http://dx.doi.org/10.1097/JU.0000000000000034DOI Listing
January 2019
1 Read

Urethral metastasis with neuroendocrine differentiation in a patient with prostate cancer treated with hormone deprivation.

Indian J Urol 2019 Jan-Mar;35(1):75-77

Department of Histopathology, Max Super Speciality Hospital, New Delhi, India.

Adenocarcinoma prostate treated with hormone deprivation may evolve into a neuroendocrine differentiated tumor. Usually visceral metastasis are seen in neuroendocrine tumors. We present a case of neuroendocrine differentiated urethral metastasis from a hormone deprived prostate cancer. Read More

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http://dx.doi.org/10.4103/iju.IJU_175_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334586PMC
January 2019
1 Read

Association Between Preoperative Magnetic Resonance Imaging-based Urethral Parameters and Continence Recovery Following Robot-assisted Radical Prostatectomy.

Eur Urol Focus 2019 Jan 25. Epub 2019 Jan 25.

Royal Marsden Hospital, London, UK.

Background: Studies demonstrated the significance of membranous urethral length (MUL) as a predictor of continence following robot-assisted radical prostatectomy (RARP). There are other magnetic resonance imaging (MRI) parameters that might be linked to continence outcome.

Objective: To evaluate the association between preoperative urethral parameters on MRI and continence outcome, to estimate the risk of incontinence using different cut-off values, and to assess interobserver variability in measuring urethral parameters. Read More

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http://dx.doi.org/10.1016/j.euf.2019.01.011DOI Listing
January 2019
1 Read

Preliminary results of using a voice-controlled robotic camera driver during 3D laparoscopic radical prostatectomy.

Cent European J Urol 2018 27;71(4):394-398. Epub 2018 Dec 27.

Department of Urology, The Faculty of Medicine and Health Sciences, University of Zielona Góra, Zielona Góra, Poland.

Introduction: During laparoscopic procedures, the surgeon's control on target field visualization as well as optimal and steady vision can be achieved by using a camera holder. The article presents our preliminary experience with the use of a voice controlled robotic camera holder during 3D laparoscopic radical prostatectomy (3D LRP).

Material And Method: Thirty patients were prospectively enrolled and underwent either 3D LRP with the use of a voice controlled robotic camera holder (study group) or 3D LRP with the surgeon holding the camera (control group). Read More

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http://dx.doi.org/10.5173/ceju.2018.1800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338813PMC
December 2018
2 Reads

Radical prostatectomy performed via robotic, transperitoneal and extraperitoneoscopic approaches: functional and early oncological outcomes.

Cent European J Urol 2018 30;71(4):378-385. Epub 2018 Oct 30.

Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.

Introduction: Oncological remission along with high postoperative functionality [continence and erectile function (EF)] are the main aspects of prostate cancer (PCa) treatment. The aim of this study was to compare functional and oncological treatment results achieved after a nerve-sparing radical prostatectomy (RP) via transperitoneal (TPRP), extraperitoneal (EPRP) and robot-assisted (RARP) approach.

Material And Methods: From March 2015 to March 2016, 507 RP were performed at the Institute for Urology and Reproductive Health (Moscow, Russia). Read More

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http://dx.doi.org/10.5173/ceju.2018.1739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338822PMC
October 2018
2 Reads

Vesicourethral anastomosis including rhabdosphincter in retropubic radical prostatectomy: Technique and results.

Arch Ital Urol Androl 2019 Jan 18;90(4):249-253. Epub 2019 Jan 18.

Haydarpaşa Numune Training and Research Hospital, Department of Urology, Istanbul.

Objective: Retropubic radical prostatectomy (RRP) is still widely used in clinical practice in localized prostate cancer because of its high oncological success. The aim of this study was to define the continence status in patients where rhabdosphincter was included in the vesicourethral anastomosis.

Materials And Methods: Between November 2004 and September 2010, 90 cases who underwent RRP by the same surgeon in our clinic were taken into the study. Read More

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http://dx.doi.org/10.4081/aiua.2018.4.249DOI Listing
January 2019
1 Read

Primary urothelial carcinoma of the prostate: A rare case report.

Medicine (Baltimore) 2019 Jan;98(3):e14155

Department of Urology, The First Affiliated Hospital of Anhui Medical University.

Rationale: Prostatic urothelial carcinoma is a rare disease. Medical misdiagnosis rates remain high because there are no specific clinical symptoms or imaging features, which decreases patient survival. We report a case of prostatic urethral cancer confirmed by transrectal ultrasound-guided prostate biopsy because of an abnormal digital rectal exam. Read More

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http://dx.doi.org/10.1097/MD.0000000000014155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370032PMC
January 2019
3 Reads
5.723 Impact Factor

Primary Small Cell Neuroendocrine Tumor Within a Urethral Diverticulum.

Obstet Gynecol 2019 Feb;133(2):308-311

Department of Obstetrics and Gynecology, Saint Louis University School of Medicine, and Saint Louis University School of Medicine, St. Louis, Missouri.

Background: Primary small cell neuroendocrine carcinoma of the urinary tract is a very rare cancer, accounting for fewer than 0.5% of urinary tract tumors. These are aggressive neoplasms with high rates of metastases. Read More

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http://dx.doi.org/10.1097/AOG.0000000000003054DOI Listing
February 2019
3 Reads

Five-Year Outcomes of a Phase 1 Dose-Escalation Study Using Stereotactic Body Radiosurgery for Patients With Low-Risk and Intermediate-Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 May 4;104(1):42-49. Epub 2019 Jan 4.

Department of Radiation Medicine, Northwell Health, Lenox Hill Hospital, New York, New York.

Purpose: To report toxicity outcomes, prostate-specific antigen (PSA) relapse, and cumulative incidence posttreatment biopsy results among patients treated on a prospective dose escalation study using ultra-hypofractionated stereotactic body radiation therapy (SBRT) for patients with low- and intermediate-risk prostate cancer.

Methods And Materials: A total of 136 patients were enrolled in a phase 1 dose-escalation study to determine the tolerance of escalating radiation dose levels of SBRT for the treatment of localized prostate cancer. The initial dose level was 32. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.12.045DOI Listing
May 2019
12 Reads

Health-related Quality of Life and Toxicity After Single-fraction High-dose-rate Brachytherapy With External Beam Radiotherapy for Localized and Locally Advanced Prostate Cancer.

Anticancer Res 2019 Jan;39(1):477-486

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan

Background/aim: To evaluate the treatment outcomes, toxicity and health-related quality of life (HRQOL) in prostate cancer (PCa) patients who underwent single-fraction high-dose-rate brachytherapy (single-fraction HDR-BT) with external beam radiotherapy (EBRT).

Materials And Methods: From April 2014 to October 2017, treatment outcomes and toxicity of 85 patients who underwent single-fraction HDR-BT of 13 Gy, followed by 46 Gy EBRT in 23 fractions, were examined. HRQOL of 53 patients was evaluated using the Expanded Prostate Cancer Index Composite (EPIC), International Prostate Symptom Score (IPSS)/QOL index, International Index of Erectile Function 5 (IIEF-5), and 36-Item Short Form Survey (SF-36) scores through one year. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13137DOI Listing
January 2019
12 Reads

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

J Magn Reson Imaging 2018 Dec 25. Epub 2018 Dec 25.

Department of Radiation Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.

Background: Post-radiotherapy locally recurrent prostate cancer (PCa) patients are candidates for focal salvage treatment. Multiparametric MRI (mp-MRI) is attractive for tumor localization. However, radiotherapy-induced tissue changes complicate image interpretation. Read More

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http://dx.doi.org/10.1002/jmri.26581DOI Listing
December 2018
5 Reads

Prognosis of rare pathological primary urethral carcinoma.

Cancer Manag Res 2018 7;10:6815-6822. Epub 2018 Dec 7.

Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China,

Purpose: Urethral carcinoma (UC), as a rare tumor, is not widely studied. There have been no systematic studies of rare pathological types of UC. We conducted this study to further investigate rare pathological types of primary urethral carcinoma (PUC). Read More

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http://dx.doi.org/10.2147/CMAR.S184197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289122PMC
December 2018
3 Reads

Pelvic Complications After Prostate Cancer Radiation Therapy and Their Management: An International Collaborative Narrative Review.

Eur Urol 2019 03 17;75(3):464-476. Epub 2018 Dec 17.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Institute for Health Policy, Management & Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Context: Radiotherapy used for treating localized prostate cancer is effective at prolonging cancer-specific and overall survival. Still, acute and late pelvic toxicities are a concern, with gastrointestinal (GI) and genitourinary (GU) sequelae being most common as well as other pelvic complications.

Objective: To present a critical review of the literature regarding the incidence and risk factors of pelvic toxicity following primary radiotherapy for prostate cancer and to provide a narrative review regarding its management. Read More

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http://dx.doi.org/10.1016/j.eururo.2018.12.003DOI Listing
March 2019
6 Reads

Cystic metastasis of prostate cancer: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13697

Department of Radiology.

Rationale: Prostate cancer often metastasizes (most commonly to the pelvic lymph nodes and axial skeleton); however, metastases to the pelvic cavity as a solitary mass are unusual. While metastatic prostate cancer is unconventional in pelvic cavity, cystic pelvic lesions are even more scarce. Accurate identification of cystic metastasis can be helpful in management of prostate cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000013697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320181PMC
December 2018
5.723 Impact Factor

Urethra and Ejaculation Preserving Robot-assisted Simple Prostatectomy: Near-infrared Fluorescence Imaging-guided Madigan Technique.

Eur Urol 2019 03 12;75(3):492-497. Epub 2018 Dec 12.

Department of Urology, "Regina Elena" National Cancer Institute, Rome, Italy.

Background: With the increasing adoption of novel technologies and anatomical techniques, surgical management of benign prostatic hyperplasia (BPH) provides significant benefits in terms of obstruction relief, early urethral catheter removal, and faster return to daily activities. However, the main pitfall of BPH surgery in sexually active men remains ejaculatory dysfunction (EjD), which permanently affects quality of life.

Objective: To detail a novel technique for marking the intraprostatic urethra through a retrograde injection of indocyanine green to enhance selective dissection of prostatic lobes during urethra-sparing robot-assisted simple prostatectomy (US-RASP) with the use of near-infrared fluorescence imaging (NIFI). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183095
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http://dx.doi.org/10.1016/j.eururo.2018.11.051DOI Listing
March 2019
21 Reads

Pelvic magnetic resonance imaging parameters predict urinary incontinence after robot-assisted radical prostatectomy.

Low Urin Tract Symptoms 2018 Dec 12. Epub 2018 Dec 12.

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

Objective: Urinary incontinence (UI) is a major prostate cancer (PCa) treatment-related morbidity. It has been reported that post-prostatectomy UI is related to the width of the pelvic floor muscles (PFM) and the length of the urethra. However, the details of these anatomical parameters are unknown. Read More

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http://dx.doi.org/10.1111/luts.12245DOI Listing
December 2018
1 Read

Prostatic Urethral Lift (PUL) for obstructive median lobes: 12 month results of the MedLift Study.

Prostate Cancer Prostatic Dis 2018 Dec 12. Epub 2018 Dec 12.

Urology of Virginia, PLLC 225 Clearfield Ave, Virginia Beach, VA, 23462, USA.

Evidence indicating Prostatic Urethral Lift (PUL) delivers significant improvement in symptomatic BPH with low morbidity is based on subjects with lateral lobe (LL) enlargement only. MedLift was an FDA IDE extension of the L.I. Read More

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http://dx.doi.org/10.1038/s41391-018-0118-xDOI Listing
December 2018

Institutional patient accrual volume and the treatment quality of I‑125 prostate seed implantation in a Japanese nationwide prospective cohort study.

Strahlenther Onkol 2018 Dec 5. Epub 2018 Dec 5.

Japanese Foundation for Prostate Research, Tokyo, Japan.

Purpose: It is unclear whether experience at high-volume institute improves the treatment quality of prostate seed implantation. The aim of this study was to evaluate the effect of institutional experience on postimplant dosimetric parameters in a nationwide prospective cohort study.

Methods: From July 2005 to June 2007, 2354 patients were registered in the Japanese Prostate Cancer Outcome Study of Permanent I‑125 Seed Implantation (J-POPS), and 1126 patients treated with seed implantation alone were evaluated. Read More

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http://link.springer.com/10.1007/s00066-018-1407-y
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http://dx.doi.org/10.1007/s00066-018-1407-yDOI Listing
December 2018
12 Reads

Use of rectal mucosal grafts in substitution urethroplasty: an early series.

Transl Androl Urol 2018 Dec;7(6):907-911

1Department of Urology, 2Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.

Background: To evaluate the feasibility of use of rectal mucosal grafts for augmentation urethroplasty.

Methods: A series of five patients who underwent rectal mucosal graft urethroplasty for urethral stricture disease were identified. Descriptive statistics were used to describe these patients. Read More

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http://tau.amegroups.com/article/view/22220/21689
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http://dx.doi.org/10.21037/tau.2018.10.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256045PMC
December 2018
10 Reads

Posterior, Anterior, and Periurethral Surgical Reconstruction of Urinary Continence Mechanisms in Robot-assisted Radical Prostatectomy: A Description and Video Compilation of Commonly Performed Surgical Techniques.

Eur Urol 2018 Dec 2. Epub 2018 Dec 2.

VU University Medical Center, Amsterdam, The Netherlands.

Background: Robot-assisted radical prostatectomy (RARP) is hampered by side effects that may have a serious impact on quality of life, particularly stress urinary incontinence. Continence rates may be improved by surgical reconstruction of the pelvic floor.

Objective: Video illustrations of different surgical techniques may be particularly worthwhile for practicing urologists in understanding the pelvic-floor anatomy and in the training of residents and fellows in urology. Read More

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http://dx.doi.org/10.1016/j.eururo.2018.11.035DOI Listing
December 2018
10 Reads