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J Matern Fetal Neonatal Med 2019 Apr 14:1-171. Epub 2019 Apr 14.

h Department of Child Health , Changning Maternal and Child Health Hospital , Shanghai , China.

Objective: The aim of this prospective observational study was to establish a suitable model for the postnatal follow-up and management of prenatal renal and urinary tract anomalies in Shanghai, China.

Methods: Minhang and Changning maternal child health care hospitals were selected to establish the integrated management model. Newborns with prenatal renal and urinary tract anomalies in these two centers were eligible to participate in the study from 2015 to 2017. Read More

Front Pediatr 2019 22;7:85. Epub 2019 Mar 22.

Department of Pediatric Urology, Children's Healthcare of Atlanta, Atlanta, GA, United States.

Robot-assisted laparoscopic (RAL) surgery is a safe, minimally invasive technique that has become more widely used in pediatric urology over recent decades. With several advantages over standard laparoscopy, robotic surgery is particularly well-suited to reconstructive surgery involving delicate structures like the ureter. A robotic approach provides excellent access to and visualization of the ureter at all levels. Read More

World J Urol 2019 Apr 5. Epub 2019 Apr 5.

Department of Urology, University of Texas Southwestern, Dallas, TX, USA.

Purpose: The introduction of robotic surgical technology into urological reconstruction, particularly pediatrics, has introduced new horizons for reducing the morbidity and enhancing the efficacy of surgical repair of congenital conditions in children. In reviewing the evolution of pediatric urological applications of robotic surgery, we wanted to address the different levels of reported utilization of pyeloplasty and ureteral reimplantation as two of the most common procedures.

Methods: Review of the published literature sought to explore the described variation in clinical application of these two common procedures, and the evolution of the practice over time. Read More

Front Pediatr 2019 19;7:83. Epub 2019 Mar 19.

Department of Pediatric Surgery and Urology, Wroclaw Medical University, Wroclaw, Poland.

Assessment of the efficacy of intraoperative diagnosis between extrinsic and intrinsic UPJO in children. Assessment of the efficacy of laparoscopic vascular-hitch procedure in UPJO caused by lower pole crossing vessels (CV). Between 2008 and 2017, 47 laparoscopic procedures were performed with the CV discovered intraoperatively. Read More

Adv Clin Exp Med 2019 Mar 27. Epub 2019 Mar 27.

Department of Pediatric Surgery and Urology, Wroclaw Medical University, Poland.

Background: A bundle of crossing vessels (CV) supplying the lower pole of the kidney and causing mechanical obstruction of the ureteropelvic junction (UPJ) has been the subject of many discussions. During pyeloplasty, it is possible to overlook the CV. This may result in recurrent dilatation of the kidney and the need for re-surgery. Read More

F1000Res 2019 15;8. Epub 2019 Mar 15.

Departement of Urology, University Hospital Aachen, Aachen, 52074, Germany.

Pyeloplasty is one of the most common urological reconstructive interventions. Since the presentation of the first open pyeloplasty by Anderson and Hynes in 1949, the management of ureteropelvic junction obstruction has dramatically developed. The most immense progress was made in the 1990s with the introduction of laparoscopy. Read More

Int J Urol 2019 Mar 18. Epub 2019 Mar 18.

Department of Pediatrics, Kansai Medical University, Hirakata, Osaka, Japan.

Objectives: To determine a follow-up plan for mild congenital hydronephrosis in Japanese individuals.

Methods: Neonates at Kansai Medical University Hospital (Hirakata, Osaka, Japan) who were diagnosed with mild congenital hydronephrosis - defined as a Society for Fetal Urology grade 1 or 2 - at 1-month old by abdominal ultrasonography between 2014 and 2016 were enrolled. These patients were encouraged to undergo repeated abdominal ultrasonography for 2 years every 3 months to investigate the course of congenital hydronephrosis. Read More

J Pediatr Urol 2019 Feb 11. Epub 2019 Feb 11.

Department of Pathology, Sri Ramachandra Institute of Higher Education and Reseach, Porur, Chennai 600116, India.

The etiology of ureterovesical junction obstruction (UVJO) and ureteropelvic junction obstruction (UPJO) is obscure with an adynamic narrow segment causing the obstruction. In this study, the authors compared interstitial cells of Cajal (ICC) and collagen-to-muscle ratio (CM ratio) between UVJO, UPJO, and fetal ureters to investigate whether a maturational arrest of the fetal ureter could explain both clinical pathologies.

Methods: Group 1 (control) involved specimens of the normal ureter (nephrectomy for trauma/tumor; n = 20), while group 2, specimens of UVJO (n = 14); group 2 was further divided into group 2a, the dilated megaureter above UVJO, and group 2b, UVJO narrow segment; group 3, UPJO narrow segment excised during pyeloplasty (n = 31); and group 4, normal fetal ureters (n = 12). Read More

J Pediatr Urol 2019 Feb 1. Epub 2019 Feb 1.

Department of Human Pathology in Adult and Developmental Age "Gaetano Barresi", University of Messina (ITALY), Messina - Viale Gazzi - AUO "Gaetano Martino", 98124 Messina, Italy.

Minerva Urol Nefrol 2019 Feb 14. Epub 2019 Feb 14.

Department of Urology, University of Florence, Careggi Hospital, Florence, Italy.

Background: The aim of the study was to describe the surgical outcomes of a series of consecutive patients treated with robot-assisted pyeloplasty (RAP) for ureteropelvic junction obstruction in a single tertiary referral centre.

Methods: We prospectively collected and retrospectively analysed data of 292 patients submitted to RAP performed from September 2011 to December 2016 by four experienced surgeons. The stenotic ureteropelvic junction was resected according to the Anderson-Hynes technique. Read More

Can Urol Assoc J 2019 Jan 21. Epub 2019 Jan 21.

Division of Urology, Department of Surgery, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada.

Introduction: Ureteropelvic junction obstruction (UPJO) is a condition characterized by partial or complete obstruction of urine transport from the renal pelvis to the ureter and can present with intermittent flank pain, recurrent urinary tract infections, renal stones, or renal dysfunction. While historically, open pyeloplasty was the gold standard for surgical management, laparoscopic methods to repair UPJO have largely taken over as the preferred approach for adolescent and adult patients. Despite near universal adoption of laparoscopic pyeloplasty among Canadian urologists, it remains a technically complex procedure and considerable variability exists in the procedural steps performed. Read More

Front Pediatr 2019 24;7. Epub 2019 Jan 24.

Division of Urology, Department of Surgery, University of Puerto Rico School of Medicine, San Juan, PR, United States.

Robotic surgery in pediatric urology has been gaining popularity since its introduction almost two decades ago. Robotic assisted pyeloplasty is the most common robotic procedure performed in pediatric urology. Advances in robotic technology, instrumentation, patient care and surgical expertise have allowed the correction of ureteropelvic junction (UPJ) obstruction in most patients using this minimally invasive technique. Read More

J Laparoendosc Adv Surg Tech A 2019 Apr 6;29(4):519-522. Epub 2019 Feb 6.

1 Urology and Nephrology Research Center, Shahid Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: The most difficult, time-consuming, and critical steps of laparoscopic pyeloplasty (LPP) are ureteral spatulation, apical ureteral stitch placement, and ureteropelvic anastomosis. To simplify these critical steps, avoid the risk of ureteral shortening, and also minimize ureteral manipulation, we present a modified dismembered technique for suturing with the outcome of patients who underwent LPP using this technique.

Materials And Methods: This study included 23 patients who were candidates for transperitoneal dismembered Anderson-Hynes LPP. Read More

Urology 2019 Apr 22;126:195-199. Epub 2019 Jan 22.

Division of Urology, McMaster University, Hamilton, ON, Canada. Electronic address:

Ureteropelvic junction obstruction (UPJO) is a common cause of upper urinary tract obstruction and consequent hydronephrosis. We present a case of right UPJO caused by a crossing vessel suspected to be the right second lumbar vein. While crossing vessels are a common cause of UPJO in older children and adults, they are usually attributed to lower pole vessels. Read More

Int Braz J Urol 2019 Jan 4;45. Epub 2019 Jan 4.

Department of Urology, Minimally Invasive Surgery Center, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.

Objective: Pyeloplasty is considered the gold standard treatment for ureteropelvic junction obstruction (UPJO). However, the failure rate of pyeloplasty is as high as 10% and repeat pyeloplasty is more difficult. This study aimed to evaluate the efficacy of balloon dilatation for failed pyeloplasty in children. Read More

World J Urol 2019 Jan 19. Epub 2019 Jan 19.

Department of Urology, The First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, 230022, Anhui Province, China.

Objective: To present our experience of combining transperitoneal robot-assisted laparoscopic pyeloplasty (RALP) and concomitant flexible cystoscope lithotomy for ureteropelvic junction obstruction (UPJO) complicated by renal caliceal stones in the same session.

Patients And Methods: Between October 2014 and November 2017, RALP combined with flexible cystoscope lithotomy was performed in 16 patients with UPJO and ipsilateral renal caliceal stones. Stone location and size were preoperatively assessed. Read More

Pediatr Int 2019 Mar 18;61(3):271-277. Epub 2019 Mar 18.

Department of Pediatric Nephrology, Dr Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey.

Background: The aim of this study was to identify the cut-offs of postnatal anteroposterior renal pelvic diameter (APRPD), according to the urinary tract dilation (UTD) classification system, to identify the predictors of final diagnosis of UTD and the need for surgery.

Methods: A total of 260 infants (336 renal units) with prenatally detected UTD were prospectively evaluated on serial ultrasonography by the same radiologist. Additional voiding cystourethrography and scintigraphy was done according to the clinical algorithm. Read More

Urol Int 2019 Jan 10:1-7. Epub 2019 Jan 10.

Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing, China.

Objective: To present our technique of laparoscopic pyeloplasty (LP) with concomitant pyelolithotomy in ureteropelvic junction obstruction (UPJO) complicated by renal calculi and compare outcome with a group of UPJO patients undergoing modified LP without coexistent calculi.

Materials And Methods: We retrospectively reviewed the charts of 51 UPJO patients undergoing modified LP from January 2013 to November 2016 at our institution. Sixteen patients were diagnosed as UPJO with coexistent ipsilateral renal calculi and underwent pyelolithotomy using our modified technique at the time of modified LP. Read More

J Laparoendosc Adv Surg Tech A 2019 Jan 7. Epub 2019 Jan 7.

Urology and Nephrology Research Center (UNRC), ShahidBeheshti University of Medical Sciences, Tehran, Iran.

Purpose: We retrospectively reviewed the perioperative outcomes of mini-laparoscopic procedure in the treatment of ureteropelvic junction obstruction (UPJO) in children and adults.

Methods: From August 2009 to March 2017, 229 patients referred to our center to repair UPJO by mini-laparoscopic operation. In 203 cases, dismembered pyeloplasty was accomplished, while in other 26 cases, crossing aberrant vein division and crossing artery upward transposition were performed. Read More

J Pediatr Urol 2019 Feb 22;15(1):18-26. Epub 2018 Nov 22.

Anatomy Lecturer, Selwyn College, University of Cambridge, Cambridge, UK.

Introduction: Robert Whitaker, inspired by Dr William W Scott at the Brady Institute at Johns Hopkins and by Sir David Innes Williams at Great Ormond Street Hospital for Children in the late 1960s, spent much of his career exploring the meaning of persistent dilatation of the upper urinary tract, in an attempt to define obstruction and to find a means of diagnosing it accurately.

Objective: This is a historical review of Bob Whitaker's journey from his definition of obstruction to the inception of his eponymous test.

Results: In 1975, he proposed a theory to explain the pathophysiology behind obstructive hydronephrosis and megaureter. Read More

J Pediatr Urol 2018 Nov 22. Epub 2018 Nov 22.

Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, Largo Gaslini 5, 16147, Genoa, Italy; DINOGMI, University of Genoa, Genoa, Italy. Electronic address:

Introduction: Ureteropelvic junction obstruction (UPJO) is one of the most common urological diseases in children. The etiology can be intrinsic, extrinsic (crossing vessel [CV] or adhesions), or mixed. To date, ultrasonography and scintigraphy are considered gold-standard imaging techniques for the study of UPJO. Read More

Urology 2019 Mar 5;125:111-117. Epub 2018 Dec 5.

Section of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, WA.

Objective: To assess the impact of presenting symptom or incidental finding on symptomatic and radiographic outcomes after robotic-assisted pyeloplasty (RAP).

Methods: We retrospectively reviewed the records of 143 patients at our institution who received pyeloplasty from 2001-2017. Patients without both pre- and postoperative radiographic data were excluded. Read More

Int Urol Nephrol 2019 Feb 5;51(2):193-199. Epub 2018 Dec 5.

Department of Urology, The Third Affiliated Hospital of Sun Yat-sen University, Tianhe Road 600, Guangzhou, 510630, Guangdong, China.

Purpose: To evaluate the effect and safety of modifying a threading cannula needle-assisted suspension fixation in retroperitoneal laparoscopic dismembered pyeloplasty (LDP) for children with congenital ureteropelvic junction obstruction (UPJO).

Methods: Between December 2012 and December 2017, 45 children (< 14 years of age) with congenital UPJO were divided into two groups. In Group A, children underwent conventional "no-suspension fixation" LDP; and in Group B, "4-point suspension fixation" LDP was performed to lower difficulties and shorten operative time. Read More

Urol Case Rep 2019 Mar 21;23:19-20. Epub 2018 Nov 21.

Departement of Urology, La Rabta Hospital, Tunisia.

Proteomics Clin Appl 2018 Nov 24:e1800101. Epub 2018 Nov 24.

Department of Pediatric Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 200092, Shanghai, China.

Purpose: Ureteropelvic junction obstruction (UPJO) is a common obstructive disease. To investigate useful urinary biomarkers in UPJO children, the urinary proteome in UPJO infants is analyzed and it is compared with normal controls.

Experimental Design: A tandem mass tag (TMT)-based quantitative proteomics study is performed to analyze the proteome of bladder urine (BU) and pelvis urine (PU) from unilateral UPJO infants with differential renal function less than 40% and they are compared with normal control urine (CON). Read More

J Indian Assoc Pediatr Surg 2018 Oct-Dec;23(4):186-191

Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India.

Aim: The aim of the study was to compare the efficacy and postoperative complications of stented and nonstented open pediatric dismembered pyeloplasty for ureteropelvic junction (UPJ) obstruction.

Settings And Design: A balanced, parallel group, prospective randomized controlled trial comparing stented and nonstented Anderson-Hynes Dismembered Pyeloplasty.

Subjects And Methods: It included 42 children who required Anderson-Hynes dismembered pyeloplasty for UPJ obstruction (UPJO). Read More

J Endourol Case Rep 2018 1;4(1):173-175. Epub 2018 Oct 1.

Heart of Florida Regional Medical Center, Davenport, Florida.

Urinary obstruction as a result of a late complication of a gunshot wound is rarely reported. Bullet shell fragments may migrate from their initial location into an area causing obstruction. In this study, we present a case of a left renal calculus surrounding a 9 mm gun shell in a patient with a solitary functioning left kidney. Read More

J Pediatr Urol 2019 Feb 17;15(1):44.e1-44.e7. Epub 2018 Oct 17.

Xinjiang Institute of Pediatrics, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China. Electronic address:

Introduction: In children with congenital ureteropelvic junction obstruction (UPJO), urinary biomarkers could assist in the diagnosis of renal damage or kidneys at risk for damage. Urinary levels of interleukin-6 (IL6), neutrophil gelatinase-associated lipocalin (LCN2), monocyte chemoattractant protein-1 (MCP1), and transforming growth factor-β1 (TGFB1) proteins have been correlated with renal damage in several contexts. Whether they might be useful non-invasive biomarkers of obstructive nephropathy due to unilateral and bilateral congenital UPJO was tested. Read More

J Pediatr Urol 2019 Feb 11;15(1):68.e1-68.e6. Epub 2018 Oct 11.

Department of Radiology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai 600116, India.

The main challenge in the management of antenatally diagnosed hydronephrosis and ureteropelvic junction obstruction (UPJO) is to differentiate the one that is likely to resolve from the pathological one. In this study, a new hydronephrosis severity score (HSS), combining ultrasonographic and renographic parameters, has been developed. Hydronephrosis severity score was analyzed with regard to its usefulness in assessing the severity of UPJO, postoperative resolution, and interobserver reliability. Read More

Cent European J Urol 2018 20;71(3):342-345. Epub 2018 Aug 20.

Department of Urology and Kidney Transplantation, Martin-Luther University, Halle (Saale), Germany.

Introduction: To prospectively compare the perioperative and functional outcomes of laparoscopic (LP) and open pyeloplasty (OP) in three academic institutions.

Material And Methods: Between September 2012 and September 2016, 102 patients with primary uteropelvic junction obstruction (UPJO) underwent pyeloplasty (51 LP and OP for the other 51 patients). Demographic data, perioperative parameters, including operative time, estimated blood loss, complications, length of hospital stay, and functional outcome were compared, and SF-8 Health Survey scoring was recorded for each group. Read More

Urol Ann 2018 Oct-Dec;10(4):358-362

Department of Urology, College of Medicine, Imam Abdulrahaman Bin Faisl University, Dammam, Saudi Arabia.

Purpose: A new minimally invasive approach for endopyelotomy for the treatment of ureteropelvic junction obstruction (UPJO) is described. The results are compared with those of other lines of treatment.

Materials And Methods: A total of 39 patients with UPJO underwent percutaneous retropelvic endopyelotomy. Read More

Urol Ann 2018 Oct-Dec;10(4):347-353

Department of Surgery, Division of Urology, College of Medicine and King Saud University Medical City, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Laparoscopic pyeloplasty (LP) is more beneficial than open procedures. However, studies on laparoscopic management of cases with secondary ureteropelvic junction obstruction (SUPJO) after previous failed pyeloplasty in the pediatric population are lacking. This meta-analysis aimed to assess the difference between redo LP (RLP) and redo open pyeloplasty (ROP) for children with SUPJO, focusing on certain criteria. Read More

J Urol 2018 Nov 6;200(5):931-933. Epub 2018 Aug 6.

J Pediatr Surg 2018 Oct 2. Epub 2018 Oct 2.

Pediatric Urology and Regenerative Medicine Research Center, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Objective: To assess the role of urinary carbohydrate antigen 19-9 (CA19-9) measurement in determining optimal management of ureteropelvic junction obstruction (UPJO) and predicting failure of conservative management.

Patients And Methods: Children with UPJO diagnosed between December 2012 and April 2015 were included. Depending on clinical and para-clinical findings, patients were divided into three groups: Group 1 consisted of patients who were considered for non-operative management with improvement of the condition during the course of follow-up. Read More

Dis Markers 2018 13;2018:1015726. Epub 2018 Sep 13.

Department of Pediatric Nephrology, Medical University of Lublin, Gębali 6, 20-093 Lublin, Poland.

Obstructive nephropathy (ON) secondary to the congenital hydronephrosis (HN) is one of the most common causes of chronic kidney disease in children. Neither currently used imaging techniques nor conventional laboratory parameters are sufficient to assess the onset and outcome of this condition; hence, there is a need to prove the usefulness of newly discovered biomarkers of kidney injury in this respect. The purpose of the study was to assess the urinary excretion of alpha-GST, pi-GST, NGAL, and KIM-1 and the serum level of NGAL in children with congenital unilateral hydronephrosis secondary to ureteropelvic junction obstruction. Read More

Pediatr Radiol 2019 02 8;49(2):175-186. Epub 2018 Oct 8.

Department of Radiology, The Children's Hospital of Philadelphia, 3401 Civic Center Blvd., Philadelphia, PA, 19104, USA.

Background: Ureteropelvic junction (UPJ) obstruction is a common cause of renal injury in children. Indications for surgery are still controversial. Currently, there is no threshold to differentiate patients with suspected UPJ obstruction requiring surgery from the ones that do not, or to predict renal outcome after surgery. Read More

Urol Case Rep 2018 Nov 24;21:110-112. Epub 2018 Sep 24.

College of Medicine, Qassim University, Saudi Arabia.

Ups J Med Sci 2018 Dec 8;123(4):216-224. Epub 2018 Oct 8.

e Department of Physiology and Pharmacology , Karolinska Institutet , Stockholm , Sweden.

Background: As much as 20% of all cases of hypertension are associated with kidney malfunctions. We have previously demonstrated in animals and in pediatric patients that hydronephrosis causes hypertension, which was attenuated by surgical relief of the ureteropelvic junction (UPJ) obstruction. This retrospective cohort study aimed to investigate: (1) the proposed link between hydronephrosis, due to UPJ obstruction, and elevated arterial pressure in adults; and (2) if elevated blood pressure in patients with hydronephrosis might be another indication for surgery. Read More

Pediatr Radiol 2019 01 3;49(1):105-113. Epub 2018 Oct 3.

Radiology Department, IRCCS Istituto Giannina Gaslini, University of Genoa, Largo Gaslini 5, 16147, Genoa, Italy.

Background: Knowing that ureteropelvic junction obstruction is due to a crossing renal vessel is essential in choosing the appropriate surgical treatment.

Objective: To evaluate the diagnostic accuracy of non-contrast magnetic resonance (MR) angiography in identifying crossing renal vessels in children younger than 4 years old with unilateral hydronephrosis.

Materials And Methods: A retrospective review of preoperative MR urography of children with unilateral hydronephrosis was conducted by two independent readers. Read More

Urol J 2018 Nov 17;15(6):339-343. Epub 2018 Nov 17.

Harran University Faculty of Medicine, Department of Urology.

Purpose: The study objective was to evaluate the safety and efficacy of mini-laparoscopic pyeloplasty (mLP) in an adult population and to demonstrate the functional and cosmetic results.

Methods: Data for 29 patients (19 men and 10 women) undergoing mLP for ureteropelvic junction obstruction (UPJO) from May 2014 to December 2016 in Turkey were collected in this prospective study. Inclusion criteria were age ? 18 years, body mass index (BMI) ? 30 kg/m2 and primary UPJO, and no previous surgery on the affected kidney or previous abdominal surgery. Read More

Urol Int 2018 19;101(3):337-344. Epub 2018 Sep 19.

Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing, China.

Objective: To compare the outcomes of modified laparoscopic pyeloplasty (LP) and robot-assisted pyeloplasty (RLP) for ureteropelvic junction obstruction (UPJO) in China patients.

Materials And Methods: We retrospectively reviewed the medical records of patients who underwent modified LP and RLP using a transperitoneal laparoscopic approach at 2 different medical institutions between October 2009 and November 2017.

Results: Seventy-six patients underwent modified LP and 140 patients underwent RLP. Read More

Intern Med 2019 Feb 12;58(4):615-616. Epub 2018 Sep 12.

Division of General Internal Medicine, Nagoya Red Cross Daini Hospital, Japan.

Eur J Pediatr 2018 Dec 12;177(12):1761-1765. Epub 2018 Sep 12.

Unit of Pediatric Surgery, Department of Human Pathology of Adult and Childhood "Gaetano Barresi", University of Messina, Messina, Italy.

The aim of the study was to retrospectively review the outcome of neonatal ureteropelvic junction obstruction with a good renal function and a poor drainage at a first diuretic renal scan, in cases where surgery was recommended on the basis of a loss of renal function, worsening of hydronephrosis or occurrence of clinical symptoms. Hydronephrosis was graded from 1 to 4 or as ureteral tract dilatation (UTD) P1 to UTD P3. During follow-up, 15 out of 38 patients (34. Read More

Turk J Urol 2018 Jul 27:1-5. Epub 2018 Jul 27.

Department of Pathology, Sakarya Training and Research Hospital, Sakarya, Turkey.

Objective: We compared the number of interstitial cells (ICs), nerves, presence of fibrosis and inflammation at the level of full-thickness human ureteropelvic junction (UPJ) tissues obtained from normal subjects, and patients with UPJ obstruction with and without crossing vessels.

Material And Methods: Normal UPJ tissues (n=12) histopathologically confirmed to be without tumor involvement were obtained from subjects who underwent radical nephrectomy for kidney mass. Additional UPJ tissues were obtained from patients who underwent pyeloplasty due to UPJ obstruction. Read More

Urology 2018 Dec 5;122:158-161. Epub 2018 Sep 5.

MUSC Department of Urology, Charleston, SC.

Objective: To assess national and regional practice patterns and rates of pathologic specimen identification sent at time of pyeloplasty, as well as project associated costs, we used a national administrative database. The rate at which the excised ureteropelvic junction obstruction (UPJO) is sent for pathologic identification is variable, arguably without a clear clinical purpose.

Materials / Methods: Utilizing a national administrative database of privately insured patients, 1496 individual cases were identified using international classification of diseases (ICD) and Current Procedural Terminology (CPT) coding. Read More

J Res Med Sci 2018 23;23:76. Epub 2018 Aug 23.

Department of Medical Physics, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: We assess the potency of different Doppler indices in the differentiation of obstructive and nonobstructive hydronephrosis.

Materials And Methods: In this study, infants and children who were referred for the evaluation of unilateral hydronephrosis were enrolled. Ultrasonography for the assessment of the degree of hydronephrosis and a voiding cystourethrogram for the exclusion of vesicoureteral reflux was performed. Read More

J Pediatr Urol 2018 Dec 2;14(6):570.e1-570.e10. Epub 2018 Aug 2.

Pediatric Surgery Department, University Teaching Hospital of Tours, Gatien de Clocheville Hospital, 37000 Tours, France.

Introduction: Few studies have evaluated the learning curve (LC) for robot-assisted laparoscopic pyeloplasty (RALP) for ureteropelvic junction obstruction in children. It was attempted to assess the LC of this procedure using a multi-outcome approach, accounting for patient complexity.

Material And Methods: Data on the first series of children undergoing RALP between November 2007 and December 2017 at the study institution were prospectively collected. Read More

BMJ Case Rep 2018 Aug 29;2018. Epub 2018 Aug 29.

Internal Medicine, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

A 25-year-old man with a history of left ureteropelvic junction (UPJ) obstruction that was corrected surgically at the age of 16 presented with a chief complaint of syncope. He was found to have severe hypertension with evidence of end organ damage on laboratory evaluation. His blood pressure was controlled with intravenous and oral antihypertensives with improvement in end organ dysfunction. Read More

J Pediatr Urol 2018 Dec 24;14(6):557.e1-557.e6. Epub 2018 Jul 24.

Division of Pediatric Urology, Riley Hospital for Children, Indiana University School of Medicine, 705 Riley Hospital Drive, Suite 4230, Indianapolis, IN, 46202, USA.

Introduction: Postobstructive diuresis (POD) after unilateral pyeloplasty or percutaneous nephrostomy (PCN) tube insertion for ureteropelvic junction obstruction (UPJO) in patients with a normal contralateral kidney is not well described.

Objective: The objective of this study was to determine the incidence and characteristics of POD after relief of unilateral UPJO in patients with a normal contralateral kidney.

Study Design: Children who underwent a unilateral pyeloplasty or PCN for UPJO from 2010 to 2017 with a normal contralateral kidney were retrospectively reviewed. Read More

Urology 2018 Nov 18;121:158-163. Epub 2018 Aug 18.

Department of Urology, Division of Pediatric Urology, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN. Electronic address:

Objective: To identify attributes of pediatric patients with hydronephrosis due to ureteropelvic junction obstruction and of their surgical encounters which are predictive of resolution of dilatation in order to provide more effective counseling about expected outcomes. This study was inspired by the suggestion in recent literature that greater than 20% improvement in anteroposterior diameter (APD) of the renal pelvis after pyeloplasty is indicative of resolution of obstruction. The remaining dilatation, however, is often distressing to caregivers, and there are no data to guide clinicians in counseling about its likelihood to resolve. Read More