3,208 results match your criteria Ureaplasma Infection


Prevalence of Ureaplasma urealyticum, Chlamydia trachomatis, Neisseria gonorrhoeae and herpes simplex virus in Beijing, China.

Epidemiol Infect 2018 Dec 3:1-5. Epub 2018 Dec 3.

Department of Infection Control,Affiliated Hospital of Academy of Military Medical Sciences,Beijing,China.

The prevalence of sexually transmitted infection (STI) pathogens in Beijing, China, is rarely reported. In this study, 34 911 symptomatic outpatients with suspected genital infections who attended outpatient clinics in a tertiary care hospital were included to investigate the updated prevalence of Ureaplasma urealyticum (UU), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) and herpes simplex virus (HSV) from 1 January 2013 to 31 December 2016 in Beijing, China. Results indicated that a decrease trend (UU, CT, NG and HSV) in male and an increase trend (UU, CT and NG) in female were observed during the period. Read More

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December 2018

Anti-inflammatory effect of a curcumin-aspirin derivative on Ureaplasma-induced cytokine expressions in neonatal monocytes.

Cell Mol Biol (Noisy-le-grand) 2018 Nov 30;64(14):61-65. Epub 2018 Nov 30.

Obstetrics, Baoji Traditional Chinese Medicine Hospital, Baoji City, Shaanxi Province, 721000, China.

One of the major contributors to death in infants is infant respiratory distress syndrome (IRDS). The transition from early acute inflammation to fibrotic hyperplasia is important in the development of IRDS. However, there are no available and effective remedies for suppression of the early inflammation. Read More

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November 2018

Adverse pregnancy and neonatal outcomes associated with a systematic review and meta-analysis protocol.

BMJ Open 2018 Nov 28;8(11):e024175. Epub 2018 Nov 28.

Public Health Interventions Research Group, Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia.

Introduction: Several bacterial sexually transmitted and genital mycoplasma infections during pregnancy have been associated with poor pregnancy and perinatal outcomes. Comprehensive and systematic information about associations between sexually transmitted infections (STI) and genital infections in pregnancy and adverse perinatal outcomes is needed to improve understanding about the evidence for causal associations between these infections and adverse pregnancy and neonatal outcomes. Our primary objective is to systematically review the literature about associations between: (1) in pregnancy and preterm birth; (2) in pregnancy and preterm birth; (3) and/or in pregnancy and preterm birth. Read More

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November 2018
1 Read

Ureaplasma urealyticum pyelonephritis presenting with progressive dysuria, renal failure and neurologic symptoms in an immunocompromised patient.

Transpl Infect Dis 2018 Nov 25:e13032. Epub 2018 Nov 25.

Washington University School of Medicine, Department of Pediatrics, Division of Infectious Diseases, Saint Louis, MO, USA.

Ureaplasma urealyticum is a bacterial species correlated with urethritis in healthy individuals and invasive infections in immunocompromised patients. We describe a 20-year-old female with history of remote heart transplant on everolimus, mycophenolate and rituximab presenting with progressive urinary tract symptoms, renal failure and neurologic symptoms. An extensive workup ultimately identified Ureaplasma urealyticum infection and the patient successfully recovered after a course of azithromycin and doxycycline. Read More

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November 2018
1 Read

Screening for Mollicutes microorganisms in perinatal calf mortality cases in Polish dairy herds.

Pol J Vet Sci 2018 Sep;21(3):441-444

Department of Immunology, Pathophysiology and Veterinary Preventive Medicine, Wroclaw University of Environmental and Life Sciences, C.K. Norwida 31 str., 50-375 Wroclaw, Poland.

Perinatal calf mortality in dairy herds has been reported worldwide. The etiology of stillbirth is multifactorial, and can be caused by various species of bacteria and environmental factors. Among them some potential pathogens from the Mollicutes class such as Mycoplasma (M. Read More

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September 2018
1 Read

Culture- and PCR-based detection of BV associated microbiological profile of the removed IUDs and correlation with the time period of IUD in place and the presence of the symptoms of genital tract infection.

Ann Clin Microbiol Antimicrob 2018 Nov 22;17(1):40. Epub 2018 Nov 22.

Institute of Clinical Microbiology, Albert Szent-Györgyi Clinical Center, Faculty of Medicine, University of Szeged, Semmelweis St. 6, Szeged, 6725, Hungary.

Objectives: The long-term use of intrauterine devices (IUDs) may lead to biofilm formation on the surface. The aim of this study was to perform the culture- and PCR-based detection of bacteria/fungi from the biofilm of the removed IUDs with different time periods in place.

Methods: For a 2-year period, 100 IUD users were involved in the study. Read More

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November 2018
4 Reads

Evaluation of the associations between cervical microbiota and HPV infection, clearance, and persistence in cytologically normal women.

Cancer Prev Res (Phila) 2018 Nov 21. Epub 2018 Nov 21.

Beijing Obstetrics and Gynecology Hospital of Capital Medical University

The aim of this study was to investigate the associations between cervical microbiota and different HPV (Human Papillomavirus) infection statuses in cytologically normal women. The cervical microbiota of HPV-positive or -negative women with a normal cytologic diagnosis was characterized and compared using 16S rDNA-based high-throughput sequencing, and the differences in cervical microbiota associated with new acquisition, persistence, and clearances of HPV genotypes were analyzed via one-year follow-up. The results showed that the cervical microbial richness of HPV-positive women was lower than for HPV-negative women, and the difference was more significant in the post-menopausal group relative to the pre-menopausal group. Read More

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November 2018
2 Reads

Effects of antenatal azithromycin for Ureaplasma spp. on neonatal outcomes.

Pediatr Int 2018 Nov 20. Epub 2018 Nov 20.

Department of Pediatrics, Hallym University Medical Center, Seoul, Korea.

Background: Ureaplasma spp. in the maternal genitourinary tract has come to the attention for is becoming more evident as a cause of preterm labor, spontaneous abortion, chorioamnionitis and adverse outcomes. However, a few controversies still remain, namely, whether it should be treated aggressively or not. Read More

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November 2018
7 Reads

[Sexually transmitted infections and male fertility].

Hautarzt 2018 Dec;69(12):1006-1013

Klinik und Poliklinik für Dermatologie und Venerologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Deutschland.

Background: Sexually transmitted infections (STI) are common worldwide and can cause impairment of fertility. In women pelvic inflammatory disease with subsequent tubal sterility is well-documented but the influence of STI on male fertility is still controversely discussed OBJECTIVE: The effects of various bacterial and viral STI on male fertility are discussed.

Material And Methods: An evaluation of the international literature up to 30 April 2018 was carried out including studies on larger collectives from the Asiatic region. Read More

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December 2018
3 Reads

Initial microbial community of the neonatal stomach immediately after birth.

Gut Microbes 2018 Nov 7:1-9. Epub 2018 Nov 7.

c Department of Bioinformatics and Genomics , University of North Carolina at Charlotte , Charlotte , USA.

The purpose of this prospective cross-sectional cohort pilot study is to explore the initial microbial community of gastric aspirate fluid as collected immediately after birth and its relationships with mode of delivery and preterm birth. Twenty-nine gastric aspirate samples collected immediately after birth from infants born between 24-40 weeks gestation were analyzed for microbial composition. Total microbial content was low in many samples, with a substantial number sharing taxonomic composition with negative controls. Read More

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November 2018
1 Read

Antibiotics for amniotic-fluid colonization by Ureaplasma and/or Mycoplasma spp. to prevent preterm birth: A randomized trial.

PLoS One 2018 7;13(11):e0206290. Epub 2018 Nov 7.

Inserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in pregnancy, Paris Descartes University, Paris, France.

Objective: To assess whether antibiotics used for treatment in asymptomatic second-trimester women positive for Mycoplasma or Ureaplasma spp. detected by amniotic-fluid PCR prevents preterm delivery.

Design: A randomized, double-blind, placebo-controlled trial. Read More

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November 2018
5 Reads

Successful treatment of Ureaplasma-induced hyperammonemia syndrome post-lung transplant.

Transpl Infect Dis 2018 Nov 7:e13022. Epub 2018 Nov 7.

Division of Allergy, Pulmonary, and Critical Care, Department of Internal Medicine, University of Wisconsin Hospital and Clinics, University of Wisconsin School of Medicine-Madison School of Medicine and Public Health, Madison, Wisconsin.

Hyperammonemia, in the absence of significant liver dysfunction, is an uncommon but often fatal occurrence following orthotopic lung transplant. Prior reports have provided evidence to support Ureaplasma species as an etiology for this syndrome. This case report describes an individual post-lung transplant, treated emperically with doxycycline along with other measures to lower ammonia levels, at the time hyperammonemia with encephalopathy was recognized. Read More

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November 2018
5 Reads

Urogenital pathogens, associated with Trichomonas vaginalis, among pregnant women in Kilifi, Kenya: a nested case-control study.

BMC Infect Dis 2018 Nov 6;18(1):549. Epub 2018 Nov 6.

Laboratory Bacteriology Research, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan, 185, Ghent, Belgium.

Background: Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with similar urogenital syndromes, remain undiagnosed and/or untreated. Some of these pathogens are associated with adverse pregnancy outcomes.

Methods: In a nested case-control study, vaginal swabs from 79 pregnant women, i. Read More

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November 2018
9 Reads

Comparison between DiaPlexQ™ STI6 and GeneFinder™ STD I/STD II multiplex Real-time PCR Kits in the detection of six sexually transmitted disease pathogens.

J Clin Lab Anal 2018 Nov 2:e22703. Epub 2018 Nov 2.

Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: The DiaPlexQ™ STI6 Detection Kit (DiaPlexQ; Solgent Co., Ltd., Daejeon, South Korea) is a multiplex real-time PCR assay for the detection of the following sexually transmitted disease (STD) pathogens: Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma hominis, Trichomonas vaginalis, Ureaplasma urealyticum, and Mycoplasma genitalium. Read More

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November 2018
5 Reads

Potential of Maintaining a Healthy Vaginal Environment by Two Strains Isolated from Cocoa Fermentation.

Biomed Res Int 2018 30;2018:7571954. Epub 2018 Sep 30.

Departamento de Ciências Biológicas, Laboratório de Imunologia, Centro de Biotecnologia e Genética, Universidade Estadual de Santa Cruz (UESC), Campus Soane Nazaré de Andrade, Salobrinho, Rodovia Jorge Amado, Km 16, 45662-900 Ilhéus, BA, Brazil.

Bacteria in the genera and do not have cell walls and therefore interact with host cells through lipid-associated membrane proteins (LAMP). These lipoproteins are important for both surface adhesion and modulation of host immune responses. and have been implicated in cases of bacterial vaginosis (BV), which can cause infertility, abortion, and premature delivery. Read More

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September 2018
6 Reads

Mycoplasma genitalium Infections in Women Attending a Sexually Transmitted Disease Clinic in New Orleans.

Clin Infect Dis 2018 Oct 23. Epub 2018 Oct 23.

Department of Medicine, Section of Infectious Diseases, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, USA.

Background: Several studies have reported statistically significant associations of Mycoplasma genitalium with cervicitis, urethritis, or vaginal discharge, although non-significant associations have also been reported. This study examined the associations of M. genitalium with selected sexually transmitted infections (STIs), demographic, behavioral, and clinical factors among women attending a sexually transmitted disease (STD) clinic in New Orleans. Read More

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October 2018
1 Read

Prevalence of Ureaplasma spp. and Mycoplasma hominis in healthy women and patients with flora alterations.

Diagn Microbiol Infect Dis 2018 Oct 4. Epub 2018 Oct 4.

Femicare Clinical Research for Women, 3300, Gasthuismolenstraat 31, Tienen, Belgium; Department of Obstetrics and Gynecology, Antwerp University, 2000, Prinsstraat 13, Antwerp, Belgium.

The objective was to estimate the prevalence of Mycoplasma hominis, Ureaplasma parvum, and Ureaplasma urealyticum in healthy women and patients with altered vaginal microflora. Vaginal samples from 2594 unselected female patients were divided into normal, bacterial vaginosis (BV), and aerobic vaginitis (AV) groups and tested for U. parvum, U. Read More

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October 2018
1 Read

Association of cervical microbial community with persistence, clearance and negativity of Human Papillomavirus in Korean women: a longitudinal study.

Sci Rep 2018 Oct 19;8(1):15479. Epub 2018 Oct 19.

Division of Cancer Epidemiology and Management, Center for Uterine Cancer, National Cancer Center, Ilsandong-gu, Goyang, Republic of Korea.

The present study aimed to identify the cervical microbes that are associated with HPV negativity, HPV clearance and HPV persistence and to assess the microbes' longitudinal associations as related to HPV infection dynamics among Korean women. We enrolled 41 women with 107 samples, and classified them according to the HPV infection dynamics: HPV negativity (21 samples, 10 subjects), HPV clearance (42 samples, 15 subjects), and HPV persistence (44 samples, 16 subjects). Cervical swabs were collected at the baseline and six-month-interval follow-up visits. Read More

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October 2018
1 Read

Correction to: Phylogenetic framework for the phylum Tenericutes based on genome sequence data: proposal for the creation of a new order Mycoplasmoidales ord. nov., containing two new families Mycoplasmoidaceae fam. nov. and Metamycoplasmataceae fam. nov. harbouring Eperythrozoon, Ureaplasma and five novel genera.

Antonie Van Leeuwenhoek 2018 Dec;111(12):2485-2486

Department of Plant and Environmental Sciences, The Alexander Silberman Institute of Life Sciences, The Hebrew University of Jerusalem, The Edmond J. Safra Campus, 9190401, Jerusalem, Israel.

In Tables 9, 10 and 11 of this paper, a few minor errors were noticed in the information for the type strains of the following new name combinations proposed in our paper. Read More

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December 2018
2 Reads

Type II restriction modification system in Ureaplasma parvum OMC-P162 strain.

PLoS One 2018 16;13(10):e0205328. Epub 2018 Oct 16.

Department of Developmental Medicine, Research Institute, Osaka Women's and Children's Hospital, Izumi City, Osaka, Japan.

Ureaplasma parvum serovar 3 strain, OMC-P162, was isolated from the human placenta of a preterm delivery at 26 weeks' gestation. In this study, we sequenced the complete genome of OMC-P162 and compared it with other serovar 3 strains isolated from patients with different clinical conditions. Ten unique genes in OMC-P162, five of which encoded for hypothetical proteins, were identified. Read More

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October 2018
9 Reads

Clinical Chorioamnionitis at Term: New Insights into the Etiology, Microbiology, and the Fetal, Maternal and Amniotic Cavity Inflammatory Responses.

Nogyogyaszati Szuleszeti Tovabbkepzo Szemle 2018 Jun;20(3):103-112

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U. S. Department of Health and Human Services, Bethesda, Maryland, and Detroit, Michigan, USA.

Clinical chorioamnionitis is the most common infection related diagnosis made in labor and delivery units worldwide. It is traditionally believed to be due to microbial invasion of the amniotic cavity, which elicits a maternal inflammatory response characterized by maternal fever, uterine tenderness, maternal tachycardia and leukocytosis. The condition is often associated with fetal tachycardia and a foul smelling amniotic fluid. Read More

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June 2018
12 Reads

Human papilloma virus genotype distribution and risk factor analysis amongst reproductive-age women in urban Gambia.

J Med Microbiol 2018 Nov 9;67(11):1645-1654. Epub 2018 Oct 9.

2​School of Life Sciences, University of Westminster, 115 New Cavendish Street, London, W1W 6UW, UK.

Purpose: Cervical cancer is the most frequently diagnosed female cancer in The Gambia, representing approximately 30 % of cases. In 2014, the quadrivalent human papilloma virus (HPV) vaccine was introduced, which offers protection against HPV genotypes 6, 11, 16 and 18. To evaluate the potential effectiveness of this vaccine, genotype distribution and risk factor analysis were assessed. Read More

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November 2018
13 Reads
2.250 Impact Factor

Airway Microbiome and Development of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review.

J Pediatr 2018 Oct 5. Epub 2018 Oct 5.

Division of Neonatology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL.

Objectives: To summarize evidence regarding microbial dysbiosis of the airway associated with bronchopulmonary dysplasia (BPD) and to explore heterogeneity among studies.

Study Design: We included studies that evaluated the airway microbiome in preterm infants who developed BPD using culture-independent molecular techniques and reported alpha- and beta-diversity metrics and microbial profiles.

Results: The 6 included studies had substantial clinical and methodological heterogeneity. Read More

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October 2018
5 Reads

Acridine-based (thio)semicarbazones and hydrazones: Synthesis, in vitro urease inhibition, molecular docking and in-silico ADME evaluation.

Bioorg Chem 2018 Sep 22;82:6-16. Epub 2018 Sep 22.

Center for Advanced Drug Research, COMSATS Institute of Information Technology, Abbottabad 22060, Pakistan. Electronic address:

Urease is a bacterial enzyme that is responsible for virulence of various pathogenic bacteria such as Staphylococcus aureus, Proteus mirabilis, Klebsiella pneumoniae, Ureaplasma urealyticum, Helicobacter pylori and Mycobacterium tuberculosis. Increased urease activity aids in survival and colonization of pathogenic bacteria causing several disorders especially gastric ulceration. Hence, urease inhibitors are used for treatment of such diseases. Read More

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September 2018
1 Read
2.150 Impact Factor

Vaginal Ureaplasma species increase chorioamnionitis in very preterm infants with preterm premature rupture of the membranes at < 28 weeks of gestation.

Eur J Clin Microbiol Infect Dis 2018 Dec 22;37(12):2371-2380. Epub 2018 Sep 22.

Department of Obstetrics and Gynecology, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.

Our aim was to investigate the association between vaginal Ureaplasma species (spp.) and the subsequent occurrence of chorioamnionitis (CAM), perinatal death, neonatal morbidity, and long-term neurodevelopmental impairments (NDIs) at 3 years of age. We analyzed 55 pregnant women with singleton pregnancy who had preterm premature rupture of the membranes (pPROM) at < 28 weeks of gestation, and delivered between 22 and 31 weeks at our tertiary hospital in 2007-2016. Read More

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December 2018
3 Reads

The gut of the finch: uniqueness of the gut microbiome of the Galápagos vampire finch.

Microbiome 2018 Sep 19;6(1):167. Epub 2018 Sep 19.

Colegio de Ciencias Biológicas y Ambientales, Universidad San Francisco de Quito, Diego de Robles y Pampite, Quito, Ecuador.

Background: Darwin's finches are a clade of 19 species of passerine birds native to the Galápagos Islands, whose biogeography, specialized beak morphologies, and dietary choices-ranging from seeds to blood-make them a classic example of adaptive radiation. While these iconic birds have been intensely studied, the composition of their gut microbiome and the factors influencing it, including host species, diet, and biogeography, has not yet been explored.

Results: We characterized the microbial community associated with 12 species of Darwin's finches using high-throughput 16S rRNA sequencing of fecal samples from 114 individuals across nine islands, including the unusual blood-feeding vampire finch (Geospiza septentrionalis) from Darwin and Wolf Islands. Read More

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September 2018

Sexually Transmitted Infections Detected by Multiplex Real Time PCR in Asymptomatic Women and Association with Cervical Intraepithelial Neoplasia.

Rev Bras Ginecol Obstet 2018 Sep 19;40(9):540-546. Epub 2018 Sep 19.

Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Objective:  To determine the frequency of sexually transmitted infections (STIs) in asymptomatic women and the association of STIs with cervical intraepithelial neoplasia (CIN).

Methods:  A cross-sectional study was performed, enrolling women examined in a general gynecology clinic and in a colposcopy referral center from October 2014 to October 2015. The colposcopy group consisted of 71 women, and the general gynecology group consisted of 55 women. Read More

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September 2018
4 Reads

Male infertility: the intracellular bacterial hypothesis.

New Microbes New Infect 2018 Nov 22;26:37-41. Epub 2018 Aug 22.

Fertility Medicine and Gynaecological Endocrinology Unit, Department Woman-Mother-Child, Lausanne University Hospital, Switzerland.

Infertility is a disease that affects one in seven couples. As male infertility affects approximately 30% of these couples with an unknown cause in half the cases, it represents a major public health concern. The classic treatment of male infertility involves intrauterine insemination, with modest outcome, and fertilization with intracytoplasmic sperm injection, which is known to be invasive and expensive, without treating the specific cause of infertility. Read More

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November 2018
1 Read

[Zhibai Dihuang Decoction improves sperm mitochondrial permeability transition in rats with ureaplasma urealyticum infection].

Zhonghua Nan Ke Xue 2018 Jun;24(6):540-546

Hunan University of Chinese Medicine, Changsha, Hunan 410208, China.

Objective: To investigate the effects of Zhibai Dihuang Decoction (ZDD) on sperm mitochondrial permeability transition (MPT) in the rat model of ureaplasma urealyticum (UU) infection (UUI).

Methods: Ninety male SD rats were randomly divide into five groups: normal control, UUI model control, ZDD, doxycycline, and ZDD + doxycycline. The UUI model was established in the latter four groups of rats by UU injection into the bladder. Read More

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June 2018
7 Reads

[Bacterial culture of donor semen: Analysis of results].

Zhonghua Nan Ke Xue 2018 Jun;24(6):504-508

Zhejiang Research Institute for Family Planning Science and Technology, Hangzhou, Zhejiang 310012, China.

Objective: To investigate bacterial infection and the distribution of different bacterial species in the donor semen and the influence of different bacterial counts on semen quality.

Methods: Bacterial colonies in the semen samples from 1 126 donors were counted with the Synbiosis Protocol 3 Automatic Colony Counter and the bacterial species with a colony count ≥10⁴ cfu/ml identified with the VITEK2 Compact Automatic Biochemical Analyzer. The Makler Sperm Counting Board was used to examine the semen quality of the semen samples with a colony count = 0 cfu/ml (n = 22, group A), those with a colony count <10⁴ cfu/ml (n = 22, group B) and those with a colony count ≥10⁴ cfu/ml (n = 22, group C). Read More

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June 2018
16 Reads

[Association of Ureaplasma urealyticum with the types of antisperm antibody in infertile men].

Zhonghua Nan Ke Xue 2018 Feb;24(2):147-151

Center of Reproductive Medicine, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu 215002, China.

Objective: To investigate the prevalence of Ureaplasma urealyticum (UU) infection in infertile men, its influence on routine semen parameters and the distribution of antisperm antibody (AsAb) and its types in infertile patients with UU infection.

Methods: We detected the positive rate of UU infection, semen parameters, and the distribution of AsAb and its types in 662 infertile men and 25 normal fertile male controls followed by comparison of the obtained data between the two groups of subjects.

Results: The positive rate of UU infection was significantly higher in the infertile men than in the normal controls (52. Read More

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February 2018
12 Reads

The Role of Polymorphonuclear Leukocyte Counts from Urethra, Cervix, and Vaginal Wet Mount in Diagnosis of Nongonococcal Lower Genital Tract Infection.

Infect Dis Obstet Gynecol 2018 26;2018:8236575. Epub 2018 Jul 26.

Oslo University Hospital, Department of Venereology, The Olafia Clinic, Norwegian National Advisory Unit on Sexually Transmitted Infections, Oslo, Norway.

Objective: The aim of this study was to evaluate whether the polymorphonuclear leukocyte (PMNL) inflammatory response in women with nongonococcal lower genital tract infection (LGTI) can be used to optimize criteria for syndromic treatment.

Methods: A cross-sectional study of 375 women attending the STI clinic in Oslo. Urethral, cervical, and vaginal specimens underwent microscopy for PMNLs. Read More

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July 2018
4 Reads

Establishment of Multiplex Loop-Mediated Isothermal Amplification for Rapid Detection of Genitourinary Mycoplasma.

Clin Lab 2018 Jul;64(7):1217-1224

Background: Genitourinary Mycoplasma (Ureaplasma urealyticum, Mycoplasma hominis, and Mycoplasma genitalium) is a common pathogen among women, which can cause funisitis, spontaneous abortion, and low birth weight. However, current laboratory testing methods for genitourinary mycoplasma normally need complex processes, expensive devices, and qualified staffs, and there are many limits for application. Up to now, the LAMP method is a rapidly developing field because of the significance for clinical application and commercial value. Read More

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Sexually transmitted agents and their association with leucocytospermia in infertility clinic patients.

Andrologia 2018 Dec 20;50(10):e13127. Epub 2018 Aug 20.

Department of Medical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

In this study, the presence of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum and Ureaplasma parvumDNA were investigated using real-time multiplex PCR detection kit in the urine samples of 50 patients who presented to the infertility polyclinic. Patients were classified into two groups in accordance with the WHO leucocytospermia criteria as over 1 × 10 /ml (n = 25) and below 1 × 10 /ml (controls; n = 25). In addition, the semen sample results of the patients were evaluated. Read More

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December 2018
9 Reads

Gut Microbiome in BALB/c and C57BL/6J Mice Undergoing Experimental Thyroid Autoimmunity Associate with Differences in Immunological Responses and Thyroid Function.

Horm Metab Res 2018 Dec 14;50(12):932-941. Epub 2018 Aug 14.

Faculty of Life Sciences & Medicine, King's College London, London, UK.

Experimental models of hyperthyroid Graves' disease (GD) and Graves' orbitopathy (GO) are efficiently developed by genetic immunisation by electroporation with human thyrotropin hormone receptor (hTSHR) A-subunit plasmid in female BALB/c (H-2d) mice. We investigated susceptibility in C57BL/6 J (H-2b) animals to allow studies on disease mechanisms in transgenic and immune response gene knock-out mice. Higher numbers of female C57BL/6 J were positive for pathogenic thyroid stimulating antibodies, but induced hyperthyroidism remained at a low frequency compared to BALB/c animals. Read More

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December 2018
1 Read

Activities of the Benzoquinolizine Fluoroquinolone Levonadifloxacin (WCK 771) and Other Antimicrobial Agents against Mycoplasmas and Ureaplasmas in Humans, Including Isolates with Defined Resistance Mechanisms.

Antimicrob Agents Chemother 2018 Nov 24;62(11). Epub 2018 Oct 24.

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA

Levonadifloxacin (WCK 771) was evaluated against 68 type strains and clinical isolates of , , , and spp. in comparison with moxifloxacin, levofloxacin, tetracycline, and azithromycin or clindamycin. Levonadifloxacin MICs were ≤0. Read More

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November 2018
5 Reads

A novel mba-based Real time PCR approach for genotyping of Ureaplasma parvum validated in a cohort of Mongolian mothers and offspring.

Int J Med Microbiol 2018 Oct 6;308(7):865-871. Epub 2018 Aug 6.

Institute of Medical Microbiology and Hospital Hygiene, University Hospital, Heinrich-Heine-University Düsseldorf, University Street, Düsseldorf, 40225, Germany. Electronic address:

The role of Ureaplasma parvum in abnormal outcomes of human pregnancy has been discussed controversially in the past. Of the 14 known ureaplasma serovars, the Ureaplasma parvum serovars 1, 3, 6 and 14, have been found to derive from smaller genomes. Serovars 3 and 6 have been described more often to cause complications in pregnancy. Read More

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October 2018

Accreditation of a multiplex real time PCR assay for detection and semi-quantitative determination of pathogens responsible of sexually-transmitted infections.

Ann Biol Clin (Paris) 2018 Aug;76(4):459-476

Laboratoire de microbiologie, Eurofins Labazur, Nice, France.

Preliminary evaluation of qualitative and semi-quantitative clinical laboratory measurements is a prerequisite for the accreditation of clinical laboratories, according to the French committee of accreditation guidelines following the European reference standard EN ISO 15189. Numerous papers have been published regarding biochemistry, hematology or immunology. However, data are still lacking for molecular biology. Read More

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August 2018
8 Reads

Investigation on silent bacterial infections in specimens from pregnant women affected by spontaneous miscarriage.

J Cell Physiol 2018 Jan 5;234(1):100-107. Epub 2018 Aug 5.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara, Ferrara, Italy.

Miscarriage is one of the main complications occurring in pregnancy. The association between adverse pregnancy outcomes and silent bacterial infections has been poorly investigated. Ureaplasma parvum and urealiticum, Mycoplasma genitalium and hominis and Chlamydia trachomatis DNA sequences have been investigated by polymerase chain reaction (PCR) methods in chorionic villi tissues and peripheral blood mononuclear cells (PBMCs) from females with spontaneous abortion (SA, n = 100) and females who underwent voluntary interruption of pregnancy (VI, n = 100). Read More

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January 2018
8 Reads

Ureaplasma urealyticum-derived lipid-associated membrane proteins introduce IL-6, IL-8, and TNF-α cytokines into human amniotic epithelial cells via Toll-like receptor 2.

J Zhejiang Univ Sci B 2018 Aug.;19(8):654-661

Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

Objective: The purpose of this study was to determine the role of Ureaplasma urealyticum-derived lipid-associated membrane proteins (LAMPs) in the host innate immune system, specifically their effect on Toll-like receptors (TLRs).

Methods: LAMPs were derived from U. urealyticum strains, and human amniotic epithelial cells (HAECs) were isolated from healthy full-term placentas. Read More

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The bacterial microbiota in first-void urine from men with and without idiopathic urethritis.

PLoS One 2018 27;13(7):e0201380. Epub 2018 Jul 27.

Department of Bacteriology, Parasitology and Mycology, Research Unit for Reproductive Tract Microbiology, Statens Serum Institut, Copenhagen, Denmark.

Background: Non-gonococcal urethritis (NGU) is a common syndrome in men. NGU may have several causes, but many cases are caused by sexually transmitted infections that may also cause complications in their female partners. Chlamydia trachomatis and Mycoplasma genitalium are the most common causes of NGU, but in up to 35% of the cases, none of the known viral or bacterial causes are found. Read More

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July 2018
2 Reads

Clonal diversity of Ureaplasma species and its relationship with oligozoospermia and semen quality in Chinese infertile males.

Eur J Clin Microbiol Infect Dis 2018 Oct 26;37(10):1957-1963. Epub 2018 Jul 26.

Department of Clinical Laboratory, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, Zhejiang, People's Republic of China.

Whether Ureaplasma spp. are a causative agent of male infertility remains controversial. Previous studies concerning Ureaplasma spp. Read More

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October 2018
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and Its Membrane-Associated Lipoproteins Activate Inflammatory Genes Through the NF-κB Pathway via Toll-Like Receptor 4.

Front Microbiol 2018 12;9:1538. Epub 2018 Jul 12.

Department of Biointeraction, Multidisciplinary Institute of Health, Universidade Federal da Bahia, Vitória da Conquista, Brazil.

is a pathogen of cows that may cause intense inflammatory responses in the reproductive tract and interfere with bovine reproduction. The aims of this study were to evaluate the immune response of bovine blastocysts and macrophages to infection and to evaluate the invasion capacity of this microorganism in bovine blastocysts. Viable and heat-inactivated strains ATCC 49782 and CI-GOTA and their extracted membrane lipoproteins were inoculated in macrophages in the presence or absence of signaling blockers of Toll-Like Receptor (TLR) 4, TLR2/4, and Nuclear Factor KB (NF-κB). Read More

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July 2018
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Ureaplasma spp. lipid-associated membrane proteins induce human monocyte U937 cell cycle arrest through p53-independent p21 pathway.

Int J Med Microbiol 2018 Oct 17;308(7):819-828. Epub 2018 Jul 17.

Clinical Laboratory, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, China; Biomedical Research Center, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310016, China. Electronic address:

Ureaplasma spp. are known to be associated with human genitourinary tract diseases and perinatal diseases and Ureaplasma spp. Lipid-associated membrane proteins (LAMPs) play important roles in their related diseases. Read More

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October 2018
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Causes and incidence of community-acquired serious infections among young children in south Asia (ANISA): an observational cohort study.

Lancet 2018 07 6;392(10142):145-159. Epub 2018 Jul 6.

Johns Hopkins Bloomberg, School of Public Health, Johns Hopkins University, Baltimore, MD, USA.

Background: More than 500 000 neonatal deaths per year result from possible serious bacterial infections (pSBIs), but the causes are largely unknown. We investigated the incidence of community-acquired infections caused by specific organisms among neonates in south Asia.

Methods: From 2011 to 2014, we identified babies through population-based pregnancy surveillance at five sites in Bangladesh, India, and Pakistan. Read More

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July 2018
11 Reads
1 Citation
45.220 Impact Factor

Garlic clove applied as vaginal suppository - A case report.

Complement Ther Med 2018 Aug 11;39:97-100. Epub 2018 Jun 11.

University of Novi Sad, Faculty of Medicine, Department of Pharmacy, Novi Sad, Serbia.

Objective: Besides conventional drugs, various vaginal disorders are often treated with complementary and alternative medicines. Different natural products are often used in treatment of genital infections. The aim is to present a case of treatment of vaginal infection with a garlic clove. Read More

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August 2018
11 Reads

Co-infection Of And Human Papilloma Virus In Asymptomatic Sexually Active Individuals.

Int J Med Sci 2018 12;15(9):915-920. Epub 2018 Jun 12.

Department of Obstetrics and Gynecology, College of Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Republic of Korea.

This study aimed to determine the role of asymptomatic bacterial sexually transmitted infections (STIs), such as (), (), , and () in human papillomavirus (HPV) infection. In total, 264 asymptomatic outpatients aged between 21 and 80 years were prospectively enrolled in this study during routine gynecological screening tests. Specimens collected with a Cervex Brush were routinely analyzed with the Hybrid Capture 2 assay for HPV. Read More

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June 2018
8 Reads

Tetracycline and fluoroquinolone resistance in clinical Ureaplasma spp. and Mycoplasma hominis isolates in France between 2010 and 2015.

J Antimicrob Chemother 2018 Oct;73(10):2696-2703

Univ. Bordeaux, USC-EA 3671 Mycoplasmal and Chlamydial Infections in Humans, Bordeaux, France.

Objectives: As information on Ureaplasma spp. and Mycoplasma hominis resistance is currently limited, the aim of this study was to investigate the susceptibility of Ureaplasma spp. and M. Read More

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October 2018
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Hyperammonemia Presenting as Refractory Status Epilepticus after Lung Transplant in a Patient Positive for .

Indian J Crit Care Med 2018 Jun;22(6):463-465

Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, USA.

Hyperammonemia is a rare complication of lung transplant with a high mortality rate. It presents as encephalopathy and progresses to seizures, status epilepticus, coma, cerebral edema, and brain death. Multiple treatments have been documented including administration of medications, gut decontamination, and dialysis. Read More

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June 2018
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Ureaplasma urealyticum: the Role as a Pathogen in Women's Health, a Systematic Review.

Curr Infect Dis Rep 2018 Jun 29;20(9):33. Epub 2018 Jun 29.

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.

Purpose Of Review: To evaluate the role of Ureaplasma urealyticum as a genital pathogen in women's health. Three aspects were analyzed: (1) preterm delivery (PTD); (2) female infertility; and (3) lower genital tract pathology including pelvic inflammatory disease (PID), cervicitis, and genital discomfort (discharge, burning).

Recent Findings: A systematic review was performed. Read More

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June 2018
31 Reads