383,546 results match your criteria Upper Respiratory Tract Infection


Incidence of Staphylococcus aureus Infections after Elective Surgeries in U.S. Hospitals.

Clin Infect Dis 2020 Jul 8. Epub 2020 Jul 8.

Departments of Medicine and Surgery; Washington University School of Medicine; St. Louis, MO, USA.

Background: Although S. aureus is a leading cause of postsurgical infections, national estimates of these infections after elective surgeries based on microbiology data are limited. This study assessed cumulative 180-day postsurgical S. Read More

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http://dx.doi.org/10.1093/cid/ciaa913DOI Listing

Renin-angiotensin system inhibitors in management of hypertension during the COVID-19 pandemic.

J Physiol Pharmacol 2020 Apr 2;71(2). Epub 2020 Jul 2.

Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, London, UK.

COVID-19, which is caused by the single-stranded RNA severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has introduced significant therapeutic dilemmas in several areas. One of these is concern regarding the use of renin-angiotensin system (RAS) inhibitors. Dysfunction of the RAS has been observed in COVID-19 patients, but whether RAS inhibitors, such as angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type-1 receptor blockers (ARBs), are associated with improved or worse clinical outcomes, remains unclear. Read More

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http://dx.doi.org/10.26402/jpp.2020.2.01DOI Listing

Incidence and clinical profiles of COVID-19 pneumonia in pregnant women: A single-centre cohort study from Spain.

EClinicalMedicine 2020 Jun 15;23:100407. Epub 2020 Jun 15.

Unit of Infectious Diseases, Hospital Universitario "12 de Octubre", Instituto de Investigación Sanitaria Hospital "12 de Octubre" (imas12), Complutense University, 2ª planta, bloque D. Avda. de Córdoba, s/n. Madrid, Spain.

Background: Information regarding the incidence and characteristics of COVID-19 pneumonia amongst pregnant women is scarce.

Methods: Single-centre experience with 32 pregnant women diagnosed with COVID-19 between March 5 to April 5, 2020 at Madrid, Spain.

Findings: COVID-19 pneumonia was diagnosed in 61·5% (32/52) women. Read More

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http://dx.doi.org/10.1016/j.eclinm.2020.100407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7295514PMC

Failure of early extubation among cases of coronavirus disease-19 respiratory failure: Case report and clinical experience.

Medicine (Baltimore) 2020 Jul;99(27):e20843

Department of Emergency, the First Affiliated Hospital, Zhejiang University, Hangzhou, China.

Rationale: Extubation strategy for mechanically ventilated patients with Coronavirus Disease 19 is different from that for patients with other viral pneumonia. We reported 2 cases of Coronavirus Disease 19 receiving tracheal intubation twice during the hospitalization.

Patient Concerns: Two elderly patients with onset of fever and upper respiratory tract infection were confirmed as Coronavirus Disease 19, 1 of whom had chronic obstructive pulmonary disease previously. Read More

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http://dx.doi.org/10.1097/MD.0000000000020843DOI Listing

Efficacy and safety of low-dose glucocorticoids combined with methotrexate and hydroxychloroquine in the treatment of early rheumatoid arthritis: A single-center, randomized, double-blind clinical trial.

Medicine (Baltimore) 2020 Jul;99(27):e20824

Department of Rheumatology.

Introduction: Glucocorticoids (GCs), especially low-dose GCs, are commonly prescribed for rheumatoid arthritis (RA), although the risk/benefit ratio is controversial. A randomized, double-blind clinical trial was performed to evaluate the efficacy and safety of low-dose oral GCs combined with methotrexate (MTX) and hydroxychloroquine (HCQ) in early RA (ERA).

Methods: Eighty untreated ERA patients were randomized into the trial (GCs + MTX + HCQ) and control (placebo + MTX + HCQ) groups, for 1-year treatment. Read More

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http://dx.doi.org/10.1097/MD.0000000000020824DOI Listing

Inflammatory Cell Infiltration of Adrenals in COVID-19.

Horm Metab Res 2020 Jul 6. Epub 2020 Jul 6.

Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was originated in November-December 2019 in Wuhan, China, and has rapidly spread around the world causing severe health and socioeconomical damage to the entire civilization. The key feature of coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is upper respiratory tract infection, which may be complicated by bilateral pneumonia. Angiotensin converting enzyme 2 (ACE2) has been identified as a key host factor, required for virus entry into cells. Read More

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http://dx.doi.org/10.1055/a-1191-8094DOI Listing

In-vitro diagnostic point-of-care tests in paediatric ambulatory care: A systematic review and meta-analysis.

PLoS One 2020 6;15(7):e0235605. Epub 2020 Jul 6.

Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, United Kingdom.

Introduction: Paediatric consultations form a significant proportion of all consultations in ambulatory care. Point-of-care tests (POCTs) may offer a potential solution to improve clinical outcomes for children by reducing diagnostic uncertainty in acute illness, and streamlining management of chronic diseases. However, their clinical impact in paediatric ambulatory care is unknown. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235605PLOS

Association Between Oral Corticosteroid Bursts and Severe Adverse Events: A Nationwide Population-Based Cohort Study.

Ann Intern Med 2020 Jul 7. Epub 2020 Jul 7.

Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan (Y.H., S.T., H.T.).

Background: Long-term use of oral corticosteroids has known adverse effects, but the risk from brief oral steroid bursts (≤14 days) is largely unknown.

Objective: To examine the associations between steroid bursts and severe adverse events, specifically gastrointestinal (GI) bleeding, sepsis, and heart failure.

Design: Self-controlled case series. Read More

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http://dx.doi.org/10.7326/M20-0432DOI Listing

[The risk and prevention of bio-aerosol transmission in dental clinics].

Shanghai Kou Qiang Yi Xue 2020 Apr;29(2):127-132

Department of General Dentistry, College of Stomatology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China.

Corona virus disease 2019 (COVID-19) has become a Public Health Emergency of International Concern since its outbreak, and whether COVID-19 can transmit by aerosol remains controversial. The problem of bio-aerosol transmission in the relatively confined dental clinics has aroused wide attention in the field of dentistry. This review provided a most updated summary on the relation between bio-aerosols and dental clinics, which included the microorganisms in bio-aerosols, the bio-aerosol transmission and the sources testing methods, temporal and spatial distribution of dental bio-aerosols and summarized how to reduce the exposure to bio-aerosols in dental clinics. Read More

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[Management and prevention of dental emergency during corona virus disease 2019 (COVID-19) epidemic].

Shanghai Kou Qiang Yi Xue 2020 Apr;29(2):123-126

Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China.

The outbreak of corona virus disease 2019 (COVID-19) has developed rapidly and the situation of prevention and control is severe. During the epidemic period of COVID-19, due to the particularity of diagnosis and treatment of oral diseases, there is great challenges for how to deal with various types of dental emergency. In order to prevent and control the epidemic situation strictly, and to perform a scientific and orderly clinical diagnosis and treatment of dental emergency, this article provided suggestions on personnel management training, procedures and treatment, protection and disinfection of dental emergency during COVID-19 epidemic, and reference for dental institutions and medical staff. Read More

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[Experts recommendation on the diagnosis and treatment of oral mucosal diseases during prevention and control stage of the novel coronavirus infection].

Authors:
Guo-Yao Tang

Shanghai Kou Qiang Yi Xue 2020 Apr;29(2):118-122

Society of Oral Medicine Shanghai Stomatological Association; Oral Mucosal Disease Specialist Alliance Organization of Shanghai Ninth People's Hospital Group.

The announcement of National Health Commission on January 20, 2020 (No. 1 of 2020) has included Novel Coronavirus Pneumonia(NCP) into the B class infectious diseases according to the law of the People's Republic of China on the prevention and control of infectious diseases, and has been managed as A class infectious diseases. People's governments at all levels and health administration departments have been paying high attention to it, and medical and health institutions have taken a series of prevention and control measures according to the law to prevent and control the spread of NCP. Read More

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[Instructions for clinical research of oral diseases under the first level response to public health emergencies].

Shanghai Kou Qiang Yi Xue 2020 Apr;29(2):113-117

National Clinical Research Center for Oral Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China.

Corona virus disease 2019(COVID-19) has swept across our country and local governments have successively initiated first level response to public health emergencies. The outbreak of COVID-19 poses a huge challenge to the implementation of various clinical researches including oral diseases. In view of the specialty of oral diseases, it is particularly necessary to protect the health and rights of the participators and related practitioners, and to standardize the implementation of clinical trials. Read More

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COVID-19 infection and diffusion among the healthcare workforce in a large university-hospital in northwest Italy.

Med Lav 2020 Jun 26;111(3):184-194. Epub 2020 Jun 26.

University of Torino, Department of Public Health and Pediatrics - Città della Salute e della Scienza di Torino University Hospital, Occupational Health Service.

Backgroud: Since the beginning of the coronavirus disease 2019 (COVID-19) outbreak, healthcare workers (HCWs) have been the workers most likely to contract the disease. Intensive focus is therefore needed on hospital strategies that minimize exposure and diffusion, confer protection and facilitate early detection and isolation of infected personnel.

Methods: To evaluate the early impact of a structured risk-management for exposed COVID-19 HCWs and describe how their characteristics contributed to infection and diffusion. Read More

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http://dx.doi.org/10.23749/mdl.v111i3.9767DOI Listing

Caring for the Carers of COVID-19.

Authors:
Anthony Seaton

Med Lav 2020 Jun 26;111(3):166-169. Epub 2020 Jun 26.

Emeritus Professor of Environmental and Occupational Medicine at Aberdeen University and Senior Consultant to the Edinburgh Institute of Occupational Medicine.

none. Read More

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http://dx.doi.org/10.23749/mdl.v111i3.9871DOI Listing

Australia's national COVID-19 primary care response.

Med J Aust 2020 Jul 4. Epub 2020 Jul 4.

College of Health and Medicine, Australian National University, Canberra, ACT.

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http://dx.doi.org/10.5694/mja2.50693DOI Listing

Reusing N95 (or P2) masks: current evidence and urgent research questions.

Med J Aust 2020 Jul 4. Epub 2020 Jul 4.

University of Sydney, Sydney, NSW.

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http://dx.doi.org/10.5694/mja2.50694DOI Listing

Genetic analysis and long-term treatment monitoring of 11 children with glycogen storage disease type IIIa.

J Pediatr Endocrinol Metab 2020 Jul 5. Epub 2020 Jul 5.

Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030,China.

Objectives To investigate the clinical and genetic characteristics of children with glycogen storage disease type IIIa (GSD IIIa) and to explore the muscle involvement and manifestations of GSD IIIa patients. Methods The clinical data of 11 patients with GSD IIIa diagnosed by genetic testing from 2003 to 2019 were retrospectively analyzed. Results Twenty variants of AGL gene were detected in 11 patients, eight of which were novel variants. Read More

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http://dx.doi.org/10.1515/jpem-2019-0453DOI Listing

The Risk of Respiratory Tract Infections in Psoriasis Patients Treated With IL-23-pathway Inhibiting Biologics: A Meta-Estimate of Pivotal Trials Relevant to Decision-Making During the COVID-19 Pandemic.

J Am Acad Dermatol 2020 Jul 2. Epub 2020 Jul 2.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.06.1014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7331500PMC

Reply to: "Do IL-17 Inhibitors Increase Risk of Respiratory Tract Infections?"

J Am Acad Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Department of Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.06.1001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7329655PMC

Do IL-17 Inhibitors Increase Risk of Respiratory Tract Infections?

J Am Acad Dermatol 2020 Jul 1. Epub 2020 Jul 1.

Oregon Medical Research Center, Portland, Oregon, USA.

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http://dx.doi.org/10.1016/j.jaad.2020.06.1000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328562PMC

Maternal respiratory infections in early pregnancy increases the risk of type 1 diabetes.

Pediatr Diabetes 2020 Jul 4. Epub 2020 Jul 4.

Crown Princess Victoria's Children's Hospital and Division of Pediatrics, Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.

Background/objective: Is exposure to maternal infections and use of antibiotics in the prenatal period associated with increased risk of T1D, regardless of genetic risk?

Methods: Data on infections and use of antibiotics during pregnancy were collected from questionnaires at birth from parents to 16292 children in the All Babies in Southeast Sweden (ABIS) cohort and validated against national diagnosis registers. As of November 2017, 137 ABIS children had developed T1D, 72 boys and 65 girls (0.8 % of the original cohort). Read More

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http://dx.doi.org/10.1111/pedi.13075DOI Listing

Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure Among Evacuees from Wuhan, China, 2020.

Emerg Infect Dis 2020 Jul 3;26(9). Epub 2020 Jul 3.

Current affiliation: Department of Health, Providence, Rhode Island, USA.

To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. Overall, 193 of 195 evacuees completed exposure surveys and submitted upper respiratory or serum specimens or both at arrival in the United States. Nearly all evacuees had taken preventive measures to limit potential exposure while in Wuhan, and none had detectable SARS-CoV-2 in upper respiratory tract specimens, suggesting the absence of asymptomatic respiratory shedding among this group at the time of testing. Read More

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http://dx.doi.org/10.3201/eid2609.201590DOI Listing

The role of NTHi colonization and infection in the pathogenesis of neutrophilic asthma.

Respir Res 2020 Jul 3;21(1):170. Epub 2020 Jul 3.

Department of Pathogen Biology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, China.

Asthma is a complex heterogeneous disease. The neutrophilic subtypes of asthma are described as persistent, more severe and corticosteroid-resistant, with higher hospitalization and mortality rates, which seriously affect the lives of asthmatic patients. With the development of high-throughput sequencing technology, an increasing amount of evidence has shown that lower airway microbiome dysbiosis contributes to the exacerbation of asthma, especially neutrophilic asthma. Read More

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http://dx.doi.org/10.1186/s12931-020-01438-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7333292PMC

A Community Hospital's Response to the COVID-19 Pandemic.

J Nurses Prof Dev 2020 Jul/Aug;36(4):253-255

Mirinda Brown Tyo, PhD, RN, TCRN, is a Nurse Residency Transitions Program Coordinator and Corporate Educator at Cape Cod Hospital, Hyannis, MA and Falmouth Hospital, Falmouth, Massachusetts. Kathleen Tardy, MSN, RN, is the Director of Clinical Education at Cape Cod Hospital, Hyannis, MA and Falmouth Hospital, Falmouth, Massachusetts. Kaitlyn Kerwin, MSN, RN, ONC, is a Medical-Surgical Clinical Educator at Cape Cod Hospital, Hyannis, Massachusetts.

The novel coronavirus 2019-nCoV (COVID-19) has disrupted and altered the way health care is delivered in the United States and across the world. Patient care guidelines and isolation recommendations continue to hastily change, demonstrating the key role of nursing professional development practitioners in educating and preparing frontline staff to provide safe patient care during the COVID-19 pandemic. This article describes a community hospital's strategic educational response to a highly contagious respiratory pandemic. Read More

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http://dx.doi.org/10.1097/NND.0000000000000656DOI Listing

Impact of Oral Care and Antisepsis on the Prevalence of Ventilator-Associated Pneumonia.

Oral Health Prev Dent 2020 Apr 1;18(2):331-336. Epub 2020 Apr 1.

Purpose: This study aimed to evaluate the impact of oral care and use of chlorhexidine gluconate on the prevention of ventilator-associated pneumonia (VAP) in patients admitted to an intensive care unit (ICU).

Materials And Methods: An evaluation was performed on 229 patients admitted to ICU in 2012 (before implementation of oral care protocol) and 329 in 2013 (after the protocol). Oral care was based on the removal of secretions from the oral cavity with 0. Read More

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http://dx.doi.org/10.3290/j.ohpd.a44443DOI Listing

Kinetics of single and dual simultaneous infection of pigs with swine influenza A virus and porcine reproductive and respiratory syndrome virus.

J Vet Intern Med 2020 Jul 3. Epub 2020 Jul 3.

Department of Preclinical Sciences and Infectious Diseases, Faculty of Veterinary Medicine and Animal Sciences, Poznan University of Life Sciences, Poznań, Poland.

Background: Simultaneous viral infections exhibit the phenomenon of viral interference, but understanding of the effect of one virus on another is limited.

Objective: Evaluate and compare clinical characteristics, immune and acute phase response, viral shedding and viral load in pigs singly and doubly inoculated with swine influenza A virus (swIAV) and porcine reproductive and respiratory syndrome virus (PRRSV).

Animals: Fifty-four 7-week-old piglets. Read More

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http://dx.doi.org/10.1111/jvim.15832DOI Listing

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population.

Open Forum Infect Dis 2020 Jun 26;7(6):ofaa194. Epub 2020 May 26.

Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA.

Background: Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately identify bacterial and viral ARI in cohorts of European and African descent. We determined classifier performance in a South Asian cohort. Read More

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http://dx.doi.org/10.1093/ofid/ofaa194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314590PMC

Staphylococcus lugdunensis: Review of Epidemiology, Complications, and Treatment.

Cureus 2020 Jun 24;12(6):e8801. Epub 2020 Jun 24.

Internal Medicine, University of Louisville, Louisville, USA.

is a species of coagulase-negative staphylococci (CNS) that induces a variety of infectious diseases, including skin and soft tissue infection (SSTI), infective endocarditis (IE), and bone and PJI. This review article underscores the important points in the literature about infections, including its epidemiology, diagnosis, and treatment, as well as specific types of infections it can cause. Anatomical and age-related distributions of SSTIs have been noted, though they most commonly occur as abscesses. Read More

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http://dx.doi.org/10.7759/cureus.8801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325404PMC

Hydroxychloroquine-induced Stevens-Johnson syndrome in COVID-19: a rare case report.

Oxf Med Case Reports 2020 Jun 25;2020(6):omaa042. Epub 2020 Jun 25.

Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

The international outbreak of respiratory illness termed coronavirus disease 2019 (COVID-19) began in December 2019 that has affected >0.8 million individuals. Self-limiting respiratory tract involvement, severe pneumonia, multiorgan failure and death are the spectrum of COVID-19. Read More

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http://dx.doi.org/10.1093/omcr/omaa042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315925PMC

Antimicrobial Susceptibility of Complex Clinical Isolates from a Chinese Tertiary Hospital.

Infect Drug Resist 2020 26;13:2001-2010. Epub 2020 Jun 26.

Department of Laboratory Medicine, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200082, People's Republic of China.

Introduction: complex (MABC) is a group of important infectious agents that are highly associated with drug resistance, and antibiotic treatment is usually ineffective. This study investigated the characteristics of antimicrobial susceptibility of MABC isolates and the synergy between certain β-lactam combinations against MABC infection.

Methods: We collected 129 MABC isolates from patients with lower respiratory tract infections and categorized them into three subspecies. Read More

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http://dx.doi.org/10.2147/IDR.S252485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326206PMC

Influence of Renin-Angiotensin System Inhibitors on Lower-Respiratory Tract Infections in Type 2 Diabetes: The Fremantle Diabetes Study Phase II.

Diabetes Care 2020 Jul 2. Epub 2020 Jul 2.

Medical School, University of Western Australia, and Fremantle Hospital, Fremantle, Western Australia, Australia.

Objective: To determine whether ACE inhibitors (ACEi) and angiotensin receptor blockers (ARB) protect against lower-respiratory tract infections complicating type 2 diabetes.

Research Design And Methods: Of 1,732 participants with diabetes recruited to the longitudinal observational Fremantle Diabetes Study Phase II (FDS2) between 2008 and 2011, 1,482 had confirmed type 2 diabetes (mean age 65.8 years and median diabetes duration 9. Read More

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http://dx.doi.org/10.2337/dc20-0895DOI Listing

Telehealth in Urology: A Systematic Review of the Literature. How Much Can Telemedicine Be Useful During and After the COVID-19 Pandemic?

Eur Urol 2020 Jun 18. Epub 2020 Jun 18.

Department of Human and Pediatric Pathology "Gaetano Barresi", Urologic Section, University of Messina, Italy.

Context: Coronavirus disease 2019 (COVID-19) pandemic has caused increased interest in the application of telehealth to provide care without exposing patients and physicians to the risk of contagion. The urological literature on the topic is sparse.

Objective: To perform a systematic review of the literature and evaluate all the available studies on urological applications of telehealth. Read More

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http://dx.doi.org/10.1016/j.eururo.2020.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301090PMC

Lung Ultrasound findings in COVID-19 Pneumonia.

Authors:
Mathias Schmid

Dtsch Arztebl Int 2020 05;117(19):335

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http://dx.doi.org/10.3238/arztebl.2020.0335DOI Listing

[Preliminary Study on Clinical Features and CT Findings of Common-type Coronavirus Disease 2019 Patients in Peking Union Medical College Hospital].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Jun;42(3):376-382

Department of Radiology.

To summarize the clinical characteristics and chest CT findings of coronavirus disease 2019(COVID-19)patients in Peking Union Medical College Hospital(PUMCH). A total of 13 patients with COVID-19 confirmed at PUMCH from January 20 to February 6,2020 were selected as the research subjects.Their epidemiological histories,clinical characteristics,laboratory tests,and chest CT findings were analyzed retrospectively. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.12588DOI Listing

[Comparison of Recovery Phase CT Features between Mild/moderate and Severe/critical Coronavirus Disease 2019 Patients].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Jun;42(3):370-375

Department of Thoracic Surgery.

To investigate the computed tomographc(CT)features of mild/moderate and severe/critical cases of coronavirus disease 2019(COVID-19)in the recovery phase. Totally 63 discharged patients in Wuhan,China,who underwent both chest CT and reverse transcription-polymerase chain reaction(RT-PCR)from February 1 to February 29,2020,were included.With RT-PCR as a gold standard,the performance of chest CT in diagnosing COVID-19 was assessed. Read More

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http://dx.doi.org/10.3881/j.issn.1000-503X.12691DOI Listing

Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis.

Crit Care 2020 Jul 2;24(1):389. Epub 2020 Jul 2.

Department of Medicine and Ageing Sciences, "G. d'Annunzio" University, Chieti-Pescara, Italy.

Background: The incidence of acute complications and mortality associated with COVID-19 remains poorly characterized. The aims of this systematic review and meta-analysis were to summarize the evidence on clinically relevant outcomes in hospitalized patients with COVID-19.

Methods: MEDLINE, EMBASE, PubMed, and medRxiv were searched up to April 20, 2020, for studies including hospitalized symptomatic adult patients with laboratory-confirmed COVID-19. Read More

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http://dx.doi.org/10.1186/s13054-020-03022-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330272PMC

Emergence of multidrug-resistant non-fermentative gram negative bacterial infection in hospitalized patients in a tertiary care center of Nepal.

BMC Res Notes 2020 Jul 2;13(1):319. Epub 2020 Jul 2.

Department of Clinical Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.

Objective: This study was designed for the characterization and establishment of antibiotic susceptibility profiles of non-fermentative gram negative bacteria isolated from hospitalized patients in a tertiary care hospital of Nepal.

Results: A total of 402 non-fermentative gram negative bacteria was isolated in 1486 culture-positive cases from 6216 different clinical samples obtained from hospitalized patients. Among total non-fermentative gram negative bacterial isolates, the highest number was recovered from specimens collected from lower respiratory tract infections (n = 173, 43. Read More

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http://dx.doi.org/10.1186/s13104-020-05163-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7330544PMC

Health assessment of harbour porpoises (PHOCOENA PHOCOENA) from Baltic area of Denmark, Germany, Poland and Latvia.

Environ Int 2020 Jun 29;143:105904. Epub 2020 Jun 29.

Department of Pathology, University of Veterinary Medicine Hannover, Foundation, Bünteweg 17, 30559 Hannover, Germany.

Harbour porpoise (Phocoena phocoena), the only resident cetacean species of the Baltic Sea is formed of two subpopulations populations, occurring in the western Baltic, Belt Seas and Kattegat and the Baltic Proper, respectively. Harbour porpoises throughout these areas are exposed to a large number of human activities causing direct and indirect effects on individuals, that might also harm this species on a population level. From Latvia, Poland, Germany and Denmark 385 out of 1769 collected dead harbour porpoises were suitable for extensive necropsy. Read More

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http://dx.doi.org/10.1016/j.envint.2020.105904DOI Listing

SARS-CoV-2 Detection, Viral Load and Infectivity over the Course of an Infection: SARS-CoV-2 Detection, Viral Load and Infectivity.

J Infect 2020 Jun 29. Epub 2020 Jun 29.

Health Information and Quality Authority, Smithfield, Dublin 7, Ireland.

Objectives: To summarise the evidence on the detection pattern and viral load of SARS-CoV-2 over the course of an infection (including any asymptomatic or pre-symptomatic phase), and the duration of infectivity.

Methods: A systematic literature search was undertaken in PubMed, Europe PubMed Central and EMBASE from 30 December 2019 to 12 May 2020.

Results: We identified 113 studies conducted in 17 countries. Read More

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http://dx.doi.org/10.1016/j.jinf.2020.06.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323671PMC

Screening of gastrointestinal cancers during COVID-19: a new emergency.

Authors:
Maida Marcello

Lancet Oncol 2020 07;21(7):e338

Gastroenterology and Endoscopy Unit, S. Elia-M. Raimondi Hospital, 93100 Caltanissetta, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(20)30341-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324111PMC

Serial Laboratory Testing for SARS-CoV-2 Infection Among Incarcerated and Detained Persons in a Correctional and Detention Facility - Louisiana, April-May 2020.

MMWR Morb Mortal Wkly Rep 2020 Jul 3;69(26):836-840. Epub 2020 Jul 3.

Transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), by asymptomatic and presymptomatic persons poses important challenges to controlling spread of the disease, particularly in congregate settings such as correctional and detention facilities (1). On March 29, 2020, a staff member in a correctional and detention facility in Louisiana developed symptoms and later had a positive test result for SARS-CoV-2. During April 2-May 7, two additional cases were detected among staff members, and 36 cases were detected among incarcerated and detained persons at the facility; these persons were removed from dormitories and isolated, and the five dormitories that they had resided in before diagnosis were quarantined. Read More

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http://dx.doi.org/10.15585/mmwr.mm6926e2DOI Listing

Screening for SARS-CoV-2 Infection Within a Psychiatric Hospital and Considerations for Limiting Transmission Within Residential Psychiatric Facilities - Wyoming, 2020.

MMWR Morb Mortal Wkly Rep 2020 Jul 3;69(26):825-829. Epub 2020 Jul 3.

In the United States, approximately 180,000 patients receive mental health services each day at approximately 4,000 inpatient and residential psychiatric facilities (1). SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), can spread rapidly within congregate residential settings (2-4), including psychiatric facilities. On April 13, 2020, two patients were transferred to Wyoming's state psychiatric hospital from a private psychiatric hospital that had confirmed COVID-19 cases among its residents and staff members (5). Read More

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http://dx.doi.org/10.15585/mmwr.mm6926a4DOI Listing

COVID-19 Outbreak Among College Students After a Spring Break Trip to Mexico - Austin, Texas, March 26-April 5, 2020.

Authors:

MMWR Morb Mortal Wkly Rep 2020 Jul 3;69(26):830-835. Epub 2020 Jul 3.

On March 27, 2020, a University of Texas at Austin student with cough, sore throat, and shortness of breath had a positive test result for SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19). On March 28, two more symptomatic students had positive test results, alerting the COVID-19 Center at the University of Texas Health Austin (UTHA) to a potential outbreak; the center initiated an outbreak investigation the same day. UTHA conducted contact tracing, which linked the students' infections to a spring break trip to Cabo San Lucas, Mexico, during March 14-19. Read More

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http://dx.doi.org/10.15585/mmwr.mm6926e1DOI Listing

Characteristics of Adult Outpatients and Inpatients with COVID-19 - 11 Academic Medical Centers, United States, March-May 2020.

MMWR Morb Mortal Wkly Rep 2020 Jul 3;69(26):841-846. Epub 2020 Jul 3.

Descriptions of coronavirus disease 2019 (COVID-19) in the United States have focused primarily on hospitalized patients. Reports documenting exposures to SARS-CoV-2, the virus that causes COVID-19, have generally been described within congregate settings, such as meat and poultry processing plants (1) and long-term care facilities (2). Understanding individual behaviors and demographic characteristics of patients with COVID-19 and risks for severe illness requiring hospitalization can inform efforts to reduce transmission. Read More

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http://dx.doi.org/10.15585/mmwr.mm6926e3DOI Listing

Exposures Before Issuance of Stay-at-Home Orders Among Persons with Laboratory-Confirmed COVID-19 - Colorado, March 2020.

MMWR Morb Mortal Wkly Rep 2020 Jul 3;69(26):847-849. Epub 2020 Jul 3.

On March 26, 2020, Colorado instituted stay-at-home orders to reduce community transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19). To inform public health messaging and measures that could be used after reopening, persons with laboratory-confirmed COVID-19 during March 9-26 from nine Colorado counties comprising approximately 80% of the state's population (Adams, Arapahoe, Boulder, Denver, Douglas, El Paso, Jefferson, Larimer, and Weld) were asked about possible exposures to SARS-CoV-2 before implementation of stay-at-home orders. Among 1,738 persons meeting the inclusion criteria in the Colorado Electronic Disease Surveillance System, 600 were randomly selected and interviewed using a standardized questionnaire by telephone. Read More

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http://dx.doi.org/10.15585/mmwr.mm6926e4DOI Listing

Epidemiological and molecular characterization of a novel adenovirus of squirrel monkeys after fatal infection during immunosuppression.

Microb Genom 2020 Jul 2. Epub 2020 Jul 2.

Keeling Center for Comparative Medicine Research, Department of Comparative Medicine, The University of Texas MD Anderson Cancer Center, Bastrop, TX, USA.

Adenoviruses are a frequent cause of acute upper respiratory tract infections that can also cause disseminated disease in immunosuppressed patients. We identified a novel adenovirus, squirrel monkey adenovirus 1 (SqMAdV-1), as the cause of fatal infection in an immunocompromised squirrel monkey () at the Keeling Center for Comparative Medicine and Research (KCCMR). Sequencing of SqMAdV-1 revealed that it is most closely related (80. Read More

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http://dx.doi.org/10.1099/mgen.0.000395DOI Listing

Pulmonary Hydatidosis - An Abandoned Surgical Approach.

Chirurgia (Bucur) 2020 May-Jun;115(3):394-403

Over the years, hydatidosis as a medical-surgical problem, has been researched by many surgeons, trying to find an optimal treatment method that produces as few as possible lung parenchyma lesions and that has as many benefits as possible for the patient. In this article, the authors are bringing to attention, an abandoned surgical method due to its possible complications but which has adapted perfectly to the case describe bellow. We present the case of a 59-year-old patient, with no significant personal pathological history for the underlying disease, who presented with minimal nonspecific symptomatology and with whom the surgical treatment performed was successful practicing the Perez-Fontana technique. Read More

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http://dx.doi.org/10.21614//chirurgia.115.3.394DOI Listing