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Trials 2020 Jun 29;21(1):590. Epub 2020 Jun 29.

Harvard Medical School, Boston, MA, USA.

Background: Critically ill infants with congenital heart disease (CHD) are often prescribed stress ulcer prophylaxis (SUP) to prevent upper gastrointestinal bleeding, despite the low incidence of stress ulcers and limited data on the safety and efficacy of SUP in infants. Recently, SUP has been associated with an increased incidence of hospital-acquired infections, community-acquired pneumonia, and necrotizing enterocolitis. The objective of this pilot study is to investigate the feasibility of performing a randomized controlled trial to assess the safety and efficacy of withholding SUP in infants with congenital heart disease admitted to the cardiac intensive care unit. Read More

Gastroenterology 2020 Jun 20. Epub 2020 Jun 20.

Division of Gastroenterology, McGill University, Montreal, Quebec, Canada.

Description: The purpose of this AGA Institute Clinical Practice Update is to review the available evidence and expert recommendations regarding the use of endoscopic therapies in treating patients with non-variceal upper GI bleeding.

Methods: This expert review was commissioned and approved by the AGA Institute Clinical Practice Updates Committee (CPUC) and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership, and underwent internal peer review by the CPUC and external peer review through standard procedures of Gastroenterology. This review is framed around the 10 best practice advice points agreed upon by the authors, which reflect landmark and recent published manuscripts in this field. Read More

Lancet 2020 Jun;395(10241):1927-1936

Background: Tranexamic acid reduces surgical bleeding and reduces death due to bleeding in patients with trauma. Meta-analyses of small trials show that tranexamic acid might decrease deaths from gastrointestinal bleeding. We aimed to assess the effects of tranexamic acid in patients with gastrointestinal bleeding. Read More

Acta Radiol 2020 Jun 17:284185120933228. Epub 2020 Jun 17.

Department of Radiology, National Cancer Center, Goyang, Republic of Korea.

Background: Aortoesophageal fistula (AEF) is a rare but fatal condition causing massive upper gastrointestinal bleeding.

Purpose: To report our experiences in the management of life-threatening AEF.

Material And Methods: A total of eight patients (seven men, one woman; mean age = 59. Read More

Aliment Pharmacol Ther 2020 Jul 7;52(2):329-339. Epub 2020 Jun 7.

Freiburg, Germany.

Background: To evaluate medical versus interventional treatment (transjugular thrombus fragmentation, local thrombolysis with or without stent implantation) in patients with acute non-cirrhotic, non-malignant portal vein thrombosis (PVT).

Methods: This prospective, observational study enrolled 65 patients with acute (<28 days since begin of symptoms, no cavernoma) PVT in nine centres. Thirty patients received medical treatment and 35 patients received interventional treatment. Read More

Khirurgiia (Mosk) 2020 (5):100-101

Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow, Russia.

Two unusual cases of anastomotic ulcer complicated by bleeding after gastric resection are reported. There were retained antrum in one patient and long 'dry' intestinal loop after laparoscopic Roux resection in another one. Emergency gastric stump resection with Haberer procedure were successfully performed in both cases. Read More

Asian J Surg 2020 May 15. Epub 2020 May 15.

Department of General Surgery, Sarawak General Hospital, Kuching, Sarawak, Malaysia.

Background: To evaluate the clinical outcomes and satisfaction of patients following laparoscopic Heller myotomy for achalasia cardia in four tertiary centers.

Methods: Fifty-five patients with achalasia cardia who underwent laparoscopic Heller myotomy between 2010 and 2019 were enrolled. The adverse events and clinical outcomes were analyzed. Read More

Am J Case Rep 2020 May 11;21:e922007. Epub 2020 May 11.

Department of Internal Medicine, Division of Hematology and Oncology, University of Michigan, Ann Arbor, MI, USA.

BACKGROUND Primary squamous cell carcinoma of the testis (tSCC) is exceptionally rare. To date, only 5 cases have been described in the literature. We report the first case of upper gastrointestinal bleeding due to a duodenal metastasis from tSCC. Read More

Surg Endosc 2020 Apr 30. Epub 2020 Apr 30.

Department of Gastroenterological Surgery, Cancer Institute Hospital of JFCR, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan.

Background: Although laparoscopic gastrectomy (LG) is a widely accepted treatment for gastric cancer, conversion to laparotomy is sometimes required. The current study aimed to review the time trends of intraoperative conversions to open procedures during the decade in which the LG procedure was being developed.

Methods: Cases in which LG was attempted at the Cancer Institute Hospital from 2005 to 2018 were retrospectively reviewed, and the details regarding conversions to open surgery were examined. Read More

Khirurgiia (Mosk) 2020 (4):70-73

Sklifosovsky Research Institute of Emergency Care of the Moscow Healthcare Department, Moscow, Russia.

Gastric diverticulum is a rather rare disease. This lesion is diagnosed in about 0.01% of cases during contrast-enhanced X-ray examination and in 0. Read More

Vasc Endovascular Surg 2020 Jul 22;54(5):455-457. Epub 2020 Apr 22.

Upper Gastrointestinal and Hepatobiliary Surgery, St Vincent's Hospital, Melbourne, Victoria, Australia.

We report a case of a 54-year-old male presenting to a regional hospital with severe hematemesis and hemodynamic instability. His medical history was significant for a previous episode of alcoholic necrotizing pancreatitis and pseudocyst, requiring cystoenterostomy drainage and debridement 10 years prior. He underwent multiple gastroscopies and one emergency laparotomy which failed to definitively treat the bleeding. Read More

Medicine (Baltimore) 2020 Apr;99(16):e19885

Department of Gastroenterology.

Rationale: Gastrointestinal stromal tumor (GIST) is one of the most common malignant mesenchymal tumors of the gastrointestinal tract. They generally arise from the fourth layer (muscularis propria) and rarely from the second or third layer. Although the manifestations of gastric stromal tumors are diverse, to our knowledge, there are only several cases of an extra-gastric stromal tumor in the literature appearing with a pedunculation. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Apr;23(4):384-389

Department of General Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, China.

To explore the safety and feasibility of da Vinci robot surgical systems in natural orifice specimen extraction surgery (NOSES) for rectal neoplasms. A descriptive cohort study was used. Inclusion criteria: (1) age ≥18 years old; (2) diagnosis of rectal cancer by biopsy via colonoscopy or benign neoplasm locating in rectum that could not be resected locally through the anus; (3) R0 resection can be achieved by preoperative evaluation; (4) the CDmax (maximum circumferential diameter) was ≤5 cm or specimens could still be extracted from the anus despite a CDmax exceeding 5 cm but was along the longitudinal axis of the rectum. Read More

BMC Gastroenterol 2020 Apr 15;20(1):105. Epub 2020 Apr 15.

Division of Gastroenterological, Department of Surgery, General and Transplant Surgery, Jichi Medical University, 3311-1, Tochigi, Yakushiji Shimotsuke, 329-0498, Japan.

Background: Capicua transcriptional repressor (CIC) -rearranged sarcoma is characterized by small round cells, histologically similar to Ewing sarcoma. However, CIC-rearranged sarcoma has different clinical, histological, and immunohistochemical features from Ewing sarcoma. It is important to differentiate between these tumors. Read More

Medicine (Baltimore) 2020 Apr;99(15):e19630

Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul.

To investigate computed tomography and angiography findings and clinical outcomes after transcatheter arterial embolization for acute upper gastrointestinal bleeding from advanced gastric cancers.From January 2005 to December 2014, 58 patients with pathologically proven gastric cancer were treated at our institution with transcatheter arterial embolization due to acute upper gastrointestinal bleeding recalcitrant to endoscopic treatment. The electronic medical records for each patient were reviewed for clinical presentation, endoscopy history, computed tomography and angiographic findings, blood transfusion requirements, and follow-up results. Read More

Mol Clin Oncol 2020 May 5;12(5):461-467. Epub 2020 Mar 5.

Department of Surgery, Faculty of Medicine, Thammasat University, Pathumthani 12120, Thailand.

Recently, there have been important developments in minimally invasive full-thickness resection of subepithelial tumors (SETs) of the upper gastrointestinal tract. However, there remain challenges with techniques such as laparoscopy-endoscopy cooperative surgery (LECS) and non-exposed endoscopic wall-inversion surgery (NEWS). The aim of the present study was to further investigate the feasibility, efficacy and safety of laparoscopy-assisted endoscopic full-thickness resection (ETFR) of SETs and to evaluate the clinical outcomes. Read More

Internist (Berl) 2020 May;61(5):513-517

Klinik Innere Medizin, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz.

This article presents the case of a 75-year-old male patient, who underwent a percutaneous abscess puncture of a liver abscess. A few days after the puncture and drainage there was a sudden onset of right upper quadrant abdominal pain accompanied by hematochezia. The patient presented with markedly elevated liver enzyme levels and a significant drop in hemoglobin concentration. Read More

J Clin Med 2020 Mar 21;9(3). Epub 2020 Mar 21.

Gastroenterology and Digestive Endoscopy Unit, AOU Città della Salute e della Scienza, University of Turin, 10126 Turin, Italy.

Endoscopic injection of glues, clotting factors, or sclerosing agents is a well-known therapy for the treatment of non-variceal upper gastrointestinal bleeding (NVUGIB), but less is known about endoscopic ultrasound (EUS)-guided treatments. In this setting, literature data are scarce, and no randomized controlled trials are available. We performed a review of the existing literature in order to evaluate the role of EUS-guided therapies in the management of NVUGIB. Read More

N Engl J Med 2020 04;382(14):1361-1363

From Yale School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven - both in Connecticut.

N Engl J Med 2020 04;382(14):1299-1308

From the Institute of Digestive Disease, the Chinese University of Hong Kong, Shatin, Hong Kong.

Background: It is recommended that patients with acute upper gastrointestinal bleeding undergo endoscopy within 24 hours after gastroenterologic consultation. The role of endoscopy performed within time frames shorter than 24 hours has not been adequately defined.

Methods: To evaluate whether urgent endoscopy improves outcomes in patients predicted to be at high risk for further bleeding or death, we randomly assigned patients with overt signs of acute upper gastrointestinal bleeding and a Glasgow-Blatchford score of 12 or higher (scores range from 0 to 23, with higher scores indicating a higher risk of further bleeding or death) to undergo endoscopy within 6 hours (urgent-endoscopy group) or between 6 and 24 hours (early-endoscopy group) after gastroenterologic consultation. Read More

Cureus 2020 Feb 21;12(2):e7068. Epub 2020 Feb 21.

Internal Medicine, Texas Tech University Health Sciences Center of the Permian Basin, Odessa, USA.

Enteritis associated with systemic lupus erythematosus (SLE) is a rare and unusual manifestation of the gastrointestinal (GI) consequences of SLE itself. Complications of the enteritis component include mesenteric vasculitis, intestinal pseudo-obstruction, and protein-losing enteropathy. Lupus enteritis is very responsive to treatment with pulse steroids in almost 70% of the patients, but it is critical to diagnose it early to prevent devastating organ damage. Read More

Sichuan Da Xue Xue Bao Yi Xue Ban 2020 Mar;51(2):236-244

West China School of Medicine, Sichuan University, Chengdu 610041, China.

Objective: To present our institutional experience in laparoscopic spleen-preserving distal pancreatectomy (Lap-SPDP) using Kimura technique with or without early occlusion of the root of the splenic artery. In addition, to explore the safety and feasibility of this occlusion technique, especially its advantages in intraoperative hemorrhage control and spleen preservation.

Methods: From February 2011 to May 2019, 54 consecutive patients who were diagnosed as benign or low-grade malignant space-occupying lesions at the body and the tail of pancreas underwent Lap-SPDP using Kimura technique in our institution. Read More

World J Gastrointest Surg 2020 Mar;12(3):104-115

First Department of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens 11527, Greece.

Background: Acute esophageal necrosis (AEN) is a rare entity with multifactorial etiology, usually presenting with signs of upper gastrointestinal bleeding.

Aim: To systematically review all available data on demographics, clinical features, outcomes and management of this medical condition.

Methods: A systematic literature search was performed with respect to the PRISMA statement (end-of-search date: October 24, 2018). Read More

Clin J Gastroenterol 2020 Mar 20. Epub 2020 Mar 20.

DASA-Diagnósticos da América SA/Laboratório Salomão Zoppi, Av. Juruá, 434. Alphaville, Barueri, SP, 06455-010, Brazil.

Primary mucosal malignant melanomas of the gastrointestinal tract are rare tumors associated to poor prognosis. Primary duodenal involvement by pigmented lesions is even more uncommon, and only a few reports exist in the literature. We report the case of a patient with large primary duodenal melanoma that presented with upper intestinal obstruction and bleeding that was submitted to urgent pancreaticoduodenectomy followed by adjuvant systemic therapy with an oral alkylating agent (temozolomide) plus intravenous cisplatin. Read More

J Radiol Case Rep 2019 Nov 30;13(11):18-23. Epub 2019 Nov 30.

Department of Radiology, San Vicente Fundación University Hospital, Medellin, Colombia.

Colopericardial fistulae constitute a condition with a very low prevalence and a high morbidity and mortality rate. In this case report, we discuss an 80-year-old male patient who presented to emergency services for massive rectal bleeding and signs of hypovolemic shock. Abdominal arteriography and upper gastrointestinal endoscopy were negative for bleeding. Read More

Medicine (Baltimore) 2020 Mar;99(11):e19485

Liver Cirrhosis Diagnosis and Treatment Center, the Fifth Medical Center of Chinese PLA General Hospital.

Urgent endoscopy (UE) is important to the diagnosis and treatment of liver cirrhosis patients with esophageal variceal bleeding (EVB). It was reported that a second-look endoscopy may benefit acute upper gastrointestinal bleeding (UGIB) caused by peptic ulcer, while whether it could improve UGIB caused by liver cirrhosis associated EVB remains unclear. This study aimed to investigate the characteristics of second UE for liver cirrhosis with EVB and further examined the potential prognostic factors. Read More

Gan To Kagaku Ryoho 2019 Dec;46(13):2380-2382

Dept. of Gastroenterological, Breast and Endocrine Surgery, Yamaguchi University Graduate School of Medicine.

An 80-year-old woman with anemia presented to our hospital. Upper gastrointestinal endoscopy revealed a 4 cm submucosal tumor(SMT)with a delle and 2 cm SMT in the upper part of the stomach. CT revealed sustained enhancement of both tumors. Read More

Isr Med Assoc J 2020 03;22(3):164-168

Institute of Gastroenterology, Nutrition, and Liver Disease, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Background: The number of investigative esophagogastroduodenoscopies (EGD) in children has increased over several decades, despite their unclear diagnostic yields.

Objectives: To evaluate the indications for performing EGD, their diagnostic yields, and consequences on pediatric patient management.

Methods: A retrospective chart review was performed of consecutive pediatric patients aged 0-18 years, who underwent EGD between January and August 2014. Read More

Am Fam Physician 2020 03;101(5):294-300

Medical College of Georgia at Augusta University, Augusta, GA, USA.

Upper gastrointestinal (GI) bleeding is defined as hemorrhage from the mouth to the ligament of Treitz. Common risk factors for upper GI bleeding include prior upper GI bleeding, anticoagulant use, high-dose nonsteroidal anti-inflammatory drug use, and older age. Causes of upper GI bleeding include peptic ulcer bleeding, gastritis, esophagitis, variceal bleeding, Mallory-Weiss syndrome, and cancer. Read More

Gastroenterology Res 2020 Feb 1;13(1):25-31. Epub 2020 Feb 1.

Department of Gastroenterology, Topiwala National Medical College and B.Y.L. Nair Charitable Hospital,Mumbai, India.

Background: Splanchnic venous system thrombosis is a well recognized local vascular complication of acute pancreatitis (AP). It may involve thrombosis of splenic vein (SplV), portal vein (PV) and superior mesenteric vein (SMV), either separately or in combinations, and often detected incidentally, indeed some cases present with upper gastrointestinal bleed, bowel ischemia and hepatic decompensation. Incidence is variable depending on study subjects and diagnostic modalities. Read More

Biosci Trends 2020 Mar 25;14(1):56-63. Epub 2020 Feb 25.

Oncology Surgery Department, Beijing Shijitan Hospital, Capital Medical University (Peking University Ninth School of Clinical Medicine), Beijing, China.

The current study describes the technical details of and the clinical prognosis for the "China stitch", a novel technique for hand-sewn esophagojejunostomy in totally laparoscopic total gastrectomy. This study also explores the feasibility and safety of the technique. Clinical data of 20 patients with esophagogastric junction cancer in Beijing Shijitan Hospital, Capital Medical University from January 2017 to April 2018 were retrospectively analyzed. Read More

Intest Res 2020 Apr 25;18(2):238-244. Epub 2020 Feb 25.

Department of Gastroenterology, Dayanand Medical College and Hospital, Ludhiana, India.

Background/aims: Opioid-induced bowel dysfunction includes nausea, vomiting, constipation and abdominal distension. We describe patients presenting with gastrointestinal (GI) ulcers and ulcerated strictures secondary to opioid abuse, an entity not well described in literature.

Methods: This retrospective observational study included patients with opioid abuse gastroenteropathy presenting to Dayanand Medical College and Hospital, Ludhiana, India between January 2013 and December 2018. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2020 Feb;23(2):177-182

Department of Gastrointestinal Surgery, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450001, China.

To investigate short-term efficacy of laparoscopic spleen-preserving splenic hilus lymphadenectomy and left epigastrium mesogastric excision for advanced proximal gastric cancer based on mesangial anatomy. A case series study was carried out. Case inclusion criteria: (1) patient was confirmed as gastric adenocarcinoma by gastroscopic biopsy before operation; (2) locally advanced gastric cancer was confirmed by abdominal CT before operation; (3) no distant metastases such as liver, lung, and posterior peritoneal lymph nodes, and no tumor directly invading the pancreas, spleen, liver, and colon were verified by superficial lymph node ultrasound, chest and abdominal CT before operation;(4) total gastrectomy or proximal gastrectomy plus D2 lymphadenectomy were performed, and R0 resection was confirmed by postoperative pathology. Read More

Zhonghua Yi Xue Za Zhi 2020 Feb;100(5):387-390

Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt(TIPS) for the treatment of patients with cavernous transformation of portal vein (CTPV) with vareceal bleeding. From September 2016 to June 2018, a total of 21 patients suffered CTPV complicated with vareceal bleeding were admitted to First Affiliated Hospital of Zhengzhou University. TIPS were performed combined with percutaneous transhepatic portal vein assist. Read More

Ann Otol Rhinol Laryngol 2020 Jul 10;129(7):689-694. Epub 2020 Feb 10.

Department of Otolaryngology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.

Objectives: Surgical procedure is considered in patients with severe dysphagia when conservative treatment fails. This study aimed to evaluate laryngeal suspension (LS) and upper esophageal sphincter (UES) myotomy for treating severe dysphagia due to brain disease.

Methods: Fourteen patients underwent LS and UES myotomy, with a median follow-up of 5 years and 6 months when conservative treatment failed. Read More

Ann Otol Rhinol Laryngol 2020 Jul 10;129(7):657-661. Epub 2020 Feb 10.

Department of Otolaryngology, Loma Linda University, Loma Linda, CA, USA.

Background: Medullary thyroid carcinoma (MTC) accounts for 1% to 2% of thyroid cancers in the United States. When identified early, total thyroidectomy is most often curative. However, in advanced disease, more aggressive treatment such as laryngectomy and esophagectomy may be indicated. Read More

Medicine (Baltimore) 2020 Jan;99(3):e18806

Department of Critical Care Medicine, Suzhou Kowloon Hospital, Shanghai Jiao tong University School of Medicine, Suzhou, China.

Rationale: Esophagopleural fistula (EPF) is a rare critical life-threatening condition that features high misdiagnosis rate. Although various surgical and conservative techniques have been developed for the treatment of EPF, the mortality rate of EPF remains high.

Patient Concerns: An 81-year-old man with hepatic cirrhosis caused by schistosomiasis was admitted with upper gastrointestinal bleeding. Read More

Cancer Radiother 2020 Feb 21;24(1):60-63. Epub 2020 Jan 21.

Department of Radiotherapy, Erasmus MC cancer Centre, Groene Hilledijk 301, Rotterdam, Netherlands.

Hemosuccus Pancreaticus (HP) is a very rare upper gastro-intestinal haemorrhagic event whose causes can be aneurismal lesions, acute and chronic pancreatic inflammatory conditions, and pancreatic masses. We present 2 cases of patients who underwent stereotactic radiotherapy for pancreatic lesions who manifested signs of HP after treatment. Two male patients were diagnosed with an inoperable locally advanced pancreatic cancer and underwent 8 cycles of chemotherapy followed by stereotactic radiotherapy to the pancreatic lesion delivering 40Gy in 8 fractions. Read More

J Ayub Med Coll Abbottabad 2019 Oct-Dec;31(4):634-635

Bassett Medical Center, United States.

Chronic Mesenteric ischemia is an episodic hypoperfusion of small intestine due to atherosclerotic narrowing of mesenteric vessels. Typically, patients report postprandial epigastric pain. The association of abdominal pain with eating results in fear of eating and weight loss. Read More

Am J Surg 2020 Aug 6;220(2):428-431. Epub 2019 Dec 6.

Department of Surgery, The University of Virginia Health System, Charlottesville, Virginia, USA.

Background: Though hemorrhoids commonly cause minor gastrointestinal bleeding, major hemorrhage requiring blood transfusion is believed to be rare. We sought to identify the prevalence and risk factors for preoperative transfusion in surgical hemorrhoidectomy patients.

Methods: Patients undergoing surgical hemorrhoidectomy at a single institution (2012-2017) were evaluated for preoperative bleeding requiring transfusion. Read More

BMC Neurol 2020 Jan 11;20(1):16. Epub 2020 Jan 11.

Department of Emergency, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1095 Jiefang Road, Wuhan, 430030, China.

Background: Cerebral arterial air embolism is a life-threatening complication that can result in neurologic deficits or death. Sometimes it is iatrogenic, presented as a complication of invasive medical procedures. Here we describe a case of cerebral arterial air embolism secondary to iatrogenic left atrial-esophageal fistula, of which the diagnosis might be covered up by the complicated pathophysiologic changes. Read More

Am Heart J 2020 03 9;221:19-28. Epub 2019 Dec 9.

Department of Cardiology, Quebec Heart and Lung Institute, Laval University, Quebec City, Canada. Electronic address:

Background: Although there have been several reports documenting complications related with transesophageal echocardiography (TEE) manipulation following cardiac surgery, there is a paucity of data regarding the safety of TEE used to guide catheter-based interventions. The aim of this study was to determine the prevalence, types and risk factors of complications associated with procedures requiring active TEE guidance.

Methods: This study included 1249 consecutive patients undergoing either transcatheter aortic valve implantation (TAVI), Mitraclip, left atrial appendage occlusion (LAAO) or paravalvular leak closure (PVLC). Read More

Am J Case Rep 2019 Dec 30;20:1966-1968. Epub 2019 Dec 30.

Division of Endocrinology, Saint George Hospital, Hadath, Lebanon.

BACKGROUND Ectopic or heterotopic pancreas is relatively rare pathology described as pancreatic tissue lacking communication with the normal pancreas. Ectopic pancreatic tissue can be found along the gastrointestinal tract, with the most common location the stomach along the greater curvature. This congenital condition could be identified incidentally, or present with symptoms that range from pain and bleeding to obstruction and malignant transformation. Read More

J Med Case Rep 2019 Dec 26;13(1):383. Epub 2019 Dec 26.

Department of General Surgery, Honjou Daiichi Hospital, 110 Iwabuchishita, Yurihonnjou, Akita, 015-8567, Japan.

Background: Edoxaban is an orally administered anticoagulant treatment that is used in patients with cerebral infarction, venous thrombosis, or other conditions, with a reported incidence of gastrointestinal hemorrhage at approximately 1%. We encountered the rare case of a patient who developed a gallbladder hemorrhage after the administration of edoxaban.

Case Presentation: An 86-year-old Japanese woman visited our gastrointestinal department due to the chief complaint of melena lasting for a week. Read More

Zhonghua Yi Xue Za Zhi 2019 Dec;99(47):3737-3740

Department of Interventional Radiology, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221006, China.

To investigate the feasibility, efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) in the individualized treatment of patients with refractory ascites and variceal hemorrhage caused by portal hypertension. Prospective study of clinical data of 47 patients with portal hypertension and refractory ascites and variceal bleeding admitted to the Affiliated Hospital of Xuzhou Medical University from August 2017 to December 2018, 26 males and 21 females, aged 23-75 (52±14) years old. The Viabahn stent was used to control the diameter of the shunt and the preoperative interval of PPG after individualized TIPS was determined according to the preoperative liver function Child-Pugh classification. Read More

Clin J Gastroenterol 2019 Dec 20. Epub 2019 Dec 20.

Department of Surgery for Inflammatory Bowel Disease, Yokohama Municipal Citizen's Hospital, 56, Okazawacho Hodogaya-ku, Yokohama City, 240-8555, Japan.

The incidence of postoperative esophageal ulcers has been rarely reported associated with severe ulcerative colitis (UC). We report two cases of esophageal ulcers accompanied by acute necrotizing esophagitis after undergoing surgery for severe UC. Both patients, 47- and 53-year-old, were diagnosed with severe UC and underwent subtotal colectomy with sigmoid mucous fistula and ileostomy. Read More

Rev Chilena Infectol 2019 Jun;36(3):387-391

Hospital Regional Lambayeque, Perú.

Primary duodenal tuberculosis is rare, even in endemic regions. The diagnosis poses a major challenge and requires a high index of suspicion, supported by imaging studies, microbiology, and histopatology obtained by endoscopic or surgical biopsy. We report the case of a 31-year-old man, without HIV infection or any previous history of tuberculosis, who presented with duodenal obstruction. Read More

Z Gastroenterol 2019 Dec 11;57(12):1476-1480. Epub 2019 Dec 11.

Clinic for Internal Medicine IV (Gastroenterology, Hepatology and Infectious Diseases), Jena University Hospital, Jena, Germany.

Aim:  We tried to identify a possible correlation between meteorological factors and the frequency of gastrointestinal bleeding (GIB).

Methods:  We analyzed all endoscopic examinations performed because of suspected GIB from 2013 to 2016 at Jena University Hospital, Germany. Confirmed bleeding events were correlated with local meteorological data and meteorological season using multivariate analysis. Read More

J Gastrointestin Liver Dis 2019 Dec 9;28(4):381. Epub 2019 Dec 9.

Gastroenterology Department, Hospital de São João, Porto, Portugal.

Med Arch 2019 Oct;73(5):359-361

Department of Gynaecology and Obstetrics, Sestre Milosrdnice University Hospital Center, Zagreb, Croatia.

Introduction: Hemiperitoneum caused by venous bleeding from the hilum of the spleen is a rare cause of acute abdomen in the last trimester of pregnancy.

Material And Methods: We are presenting a case of a twenty-nine-year-old primipara with the clinical picture of acute abdomen.

Case Report: Primipara in the 36th week of pregnancy presented with the clinical picture of acute abdomen with the ultrasound finding of free fluid in the abdominal cavity and foetal bradycardia. Read More