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BMC Gastroenterol 2021 Jun 6;21(1):250. Epub 2021 Jun 6.

Department of Gastroenterology, Xuanwu Hospital of Capital Medical University, 45 Chang-chun Street, Beijing, 100053, China.

Background: Few studies have reported whether a biopsy in emergency gastroscopy (EG) increased the risk of rebleeding in patients with Forrest I acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) combined with suspected malignant gastric ulcer (SMGU). This study aims to conduct a multicenter retrospective cohort study using propensity score matching to verify whether a biopsy in EG increases the risk of rebleeding in patients diagnosed with Forrest I ANVUGIB combined with SMGU.

Methods: Using the data for propensity-matched patients, logistic regression models were fitted using rebleeding as the dependent variable. Read More

Clin Endosc 2021 May 25. Epub 2021 May 25.

Department of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile.

The Roux-en-Y gastric bypass is one of the most extensive surgical treatments for obesity. The treatment of upper gastrointestinal bleeding after Roux-en-Y gastric bypass is complex due to the difficulty of accessing the excluded gastric antrum and duodenal bulb. There is no consensus regarding the management of this complication. Read More

Khirurgiia (Mosk) 2021 (6):38-44

State Novosibirsk Regional Clinical Hospital, Novosibirsk, Russia.

Objective: To evaluate the results of diagnosis and treatment of foreign bodies of the upper gastrointestinal tract.

Material And Methods: There were 1187 patients aged 15-99 years with suspected foreign body of the upper gastrointestinal tract. In 536 patients (266 men, 270 women), foreign bodies were detected. Read More

Medicine (Baltimore) 2021 May;100(20):e25785

Hepatic Surgery Center, Department of Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Rationale: Esophageal carcinoma is an aggressive cancer with extremely poor therapeutic outcomes due to its high metastatic potential and a significant risk of recurrence after radical resection. Liver is the most common metastatic target organ of esophageal carcinoma, followed by the lungs, bones, and brain. Few cases of solitary pancreatic and hepatic metastases of esophageal carcinoma have been reported. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2021 May;24(5):449-451

Department of Bariatric and Metabolic Surgery, China-Japan Union Hospital, Jilin University, Changchun 130033, China.

Single-anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) is simpler and has similar efficacy for obesity and obesity-associated metabolic diseases in comparison to biliopancreatic diversion with duodenal switch. We reported the first Da Vinci robot-assisted SADI-S in the treatment of severe obesity in China. This male patient was 27-year-old with height of 180 cm, body weight of 140 kg, waistline of 125 cm and body mass index of 43. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2021 May;24(5):420-425

Department of General Surgery, The Affiliated Tumor Hospital, Zhengzhou University, Zhengzhou 450008, China.

To compare the efficacy between laparoscopic and open proximal gastrectomy with double-tract reconstruction for Siewert type II and III adenocarcinoma of the esophagogastric junction (AEG). A retrospective cohort study was conducted. Inclusion criteria: (1) 18 to 80 years old; (2) Siewert II and III AEG was confirmed by preoperative gastroscopy and biopsy, which could not be resected by endoscopy; patients undergoing radical proximal gastrectomy with double-tract reconstruction; (3) contrast-enhanced abdominal CT staging was cT1-2N0M0; (4) Eastern Cooperative Oncology Group (ECOG) physical status score <2 points, American Association of Anesthesiologists (ASA) grade 1 to 2; (5) patients agreed to perform proximal gastrectomy and signed an informed consent. Read More

Cureus 2021 Apr 8;13(4):e14368. Epub 2021 Apr 8.

Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.

Bouveret's syndrome is a rare complication of cholelithiasis. It is characterized by a gallstone entering the intestine through a cholecystoenteric fistula, impacting the duodenum and causing gastric outlet obstruction. Rarely, it presents with hematemesis and melena. Read More

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(5):462-472

Department of Internal Medicine II, Shimane University.

A 57-year-old female with a history of Cowden's disease was referred to our hospital because of black stool, loss of consciousness, and severe anemia. Upper and lower gastrointestinal endoscopy findings could not confirm the source of hemorrhage. Capsule endoscopy (CE) of the small intestine showed an active exudative hemorrhagic site near the ileum, although a definitive diagnosis was difficult. Read More

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2021 Apr;43(2):222-229

Department of Gastroenterology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Objective To analyze clinical characteristics and short-term efficacy of endoscopic hemostasis in acute duodenal hemorrhage. Methods A retrospective study was conducted for the patients who received endoscopy in the PUMC Hospital due to upper gastrointestinal bleeding and were confirmed to be on account of duodenal lesions for bleeding from January 2011 to December 2018.Clinical information of patients was collected,including demographics,comorbidities,and medication use. Read More

BMC Gastroenterol 2021 May 7;21(1):205. Epub 2021 May 7.

Division of Digestive and Liver Diseases, University of Miami Miller School of Medicine, Miami, FL, USA.

Background And Aims: Gastrointestinal manifestations in patients with COVID-19 are common but the role of endoscopy in this patient population remains unclear. We investigated the need for endoscopic procedures, their findings, and impact on patient care in a systematic and geographically diverse sample of patients hospitalized with COVID-19.

Methods: As part of the North American Alliance for the Study of Digestive Manifestations of COVID-19, we identified consecutive patients hospitalized with COVID-19 at 36 medical centers in the USA and Canada. Read More

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Mar;46(3):278-282

Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Objectives: To study the risk factors for complications after endoscopic therapy for upper gastrointestinal subepithelial lesions (SELs).

Methods: Retrospective analysis was performed on 184 patients in the Department of Gastroenterology in the Third Xiangya Hospital, Central South University after therapeutic endoscopy [endoscopic submucosal dissection (ESD), endoscopic full-thickness resection (EFR), endoscopic submucosal excavation (ESE), and submucosal tunneling endoscopic resection (STER)] for the upper gastrointestinal SELs from 2014-09-01 to 2019-09-30. The clinic data were collected and risk factors for postoperative complications were analyzed. Read More

Esophagus 2021 Apr 23. Epub 2021 Apr 23.

Department of Surgery, Jikei University School of Medicine, 3-25-8 Nishishinbashi, Minato-ku, Tokyo, 105-8461, Japan.

Background And Objectives: The Lyon Consensus was conducted in 2017, leading to a revision of the diagnostic criteria of GERD. Conclusive GERD was defined as cases in which the distal esophageal acid exposure time (AET) is greater than 6% and there exists either peptic esophagitis, constriction, or long-segment Barrett's mucosa with a Los Angeles classification of grade C or D. Borderline GERD is defined as cases in which AET is between 4 and 6% and there exists peptic esophagitis with a Los Angeles classification of either grade A or B. Read More

Int J Surg Case Rep 2021 Apr 23;81:105802. Epub 2021 Mar 23.

Department of General Surgery, Qatif Central Hospital, Qatif, Saudi Arabia.

Introduction: Glomus tumors are rare neoplasms that aris-e from neuromyoarterial canal or glomus body. They are mainly found in the peripheral soft tissue, extremities and rarely developed inside the gastrointestinal tract. In the gastrointestinal tract, the stomach is the most common site for the development of glomus tumors, and most often found in the antrum. Read More

Gastrointest Endosc 2021 Apr 19. Epub 2021 Apr 19.

Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, Amsterdam Gastroenterology Endocrinology & Metabolism, Amsterdam, the Netherlands. Electronic address:

Background And Aims: Consensus regarding an optimal algorithm for endoscopic treatment of papillary adenomas has not been established. We aimed to assess the existing degree of consensus among international experts and develop further concordance by means of a Delphi process.

Methods: A total of 52 international experts in the field of endoscopic papillectomy were invited to participate. Read More

Ital J Pediatr 2021 Apr 21;47(1):98. Epub 2021 Apr 21.

Department of Translational Medical Science, Section of Pediatrics, University of Naples "Federico II", Via S. Pansini, 5, 80131, Naples, Italy.

Background: Despite ibuprofen widely recognized safety profile, an increase of suspected adverse events has been reported in the last decade in parallel with its growing over-the-counter use. The aims of this study were to assess the therapeutic approach to the feverish child and to evaluate the main indications and the most frequent adverse events related to ibuprofen administration in children.

Methods: A specific questionnaire-form regarding the management of ibuprofen therapy in children was distributed among a sample of pediatricians all over the Italian territory between September and October 2020. Read More

Medicine (Baltimore) 2021 Apr;100(16):e25347

Department of General and Gastroenterological Surgery.

Introduction: Gastric varices can be present in up to 20% of patients with portal hypertension. However, a varix of the left gastroepiploic vein (LGV) is extremely rare. Surgery is required if bleeding occurs; thus, precise diagnosis is crucial. Read More

Wounds 2021 Apr;33(4):99-105

Rubin Institute for Advanced Orthopedics, Baltimore, Maryland.

Introduction: The COVID-19 virus is caused by the new coronavirus, SARS-CoV-2. COVID-19 has drastically changed the medical landscape. Although predominantly impacting the respiratory system, COVID-19 has several non-respiratory symptoms associated with its presentation and course. Read More

BMJ Case Rep 2021 Apr 15;14(4). Epub 2021 Apr 15.

Department of General Surgery, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

Endoscopic procedures are the front-runner of the management of bleeding duodenal ulcer. Rarely, surgical intervention is sought for acute bleeding, not amenable to endoscopic procedures. Oversewing of the gastroduodenal artery at ulcer crater by transduodenal approach is the most acceptable and recommended method of treatment. Read More

Z Gastroenterol 2021 May 9;59(5):446-453. Epub 2021 Apr 9.

ALGK (Arbeitsgemeinschaft Leitende Gastroenterologische Krankenhausärzte; Working Group of Leading German Gastroenterologists in Hospitals).

Background And Study Aims:  Gastrointestinal bleeding is frequently observed in the German population. However, recent epidemiological data are not available. This study aimed to elucidate gastrointestinal bleeds under real-life conditions in 3 German hospitals. Read More

Vasc Health Risk Manag 2021 31;17:123-133. Epub 2021 Mar 31.

Faculty of Medicine, Department of Psychiatry, Medical University of Gdansk, Gdansk, Poland.

Background: The current ERC guidelines are the source of many positive changes, reduction of mortality, length of hospitalization and improvement of prognosis of STEMI patients. However, there is a small group of patients whose slight modification in guidelines would further reduce in-hospital mortality and hospitalization costs. These are patients with concomitant STEMI infarction and gastrointestinal bleeding. Read More

Gan To Kagaku Ryoho 2021 Mar;48(3):410-412

Dept. of Surgery, Sosa Municipal Hospital.

A 67-year-old man was admitted to our hospital because of nausea, anorexia and tarry stool. In the blood examination, serum α-fetoprotein(AFP)level was 1,650 ng/mL, and the upper gastrointestinal endoscopy showed a large hemorrhage tumor at the gastric body. Abdominal enhanced computed tomography(CT)showed a solitary mass in segment 4 of the liver. Read More

Eur J Case Rep Intern Med 2021 23;8(3):002134. Epub 2021 Feb 23.

Department of Internal Medicine, Clinic Barmelweid, Barmelweid, Switzerland.

Introduction: Arterio-oesophageal fistulae are a very uncommon cause of severe gastrointestinal bleeding, and mostly result from an aberrant right subclavian artery and mediastinal surgery or prolonged endotracheal/nasogastric intubation.

Material And Methods: We present the case of a patient with an oesophageal adenocarcinoma and haematemesis due to a subclavian arterio-oesophageal fistula after mediastinal radiotherapy.

Conclusion: We discuss the rare, life-threatening condition of acute erosion of the left subclavian artery caused by an oesophageal tumour and presenting with Chiari's triad. Read More

Medicine (Baltimore) 2021 Mar;100(12):e24697

Department of Pathology, Lanzhou University Second Hospital, Lanzhou, Gansu Province, China.

Rationale: Carcinosarcoma and sarcomatoid carcinoma of the stomach are rare, malignant, and biphasic tumors with high mortality. The differential diagnosis of these 2 diseases remains challenging. In the present study, we present 2 cases of carcinosarcoma and sarcomatoid carcinoma of the stomach. Read More

Zhonghua Zhong Liu Za Zhi 2021 Mar;43(3):329-334

Department of Endoscope, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To discuss the efficacy and safety of endoscopic papillectomy of major duodenal papilla neoplasms. The clinical-pathological data of 21 patients who were admitted to the Department of Endoscopy, Cancer Hospital, Chinese Academy of Medical Sciences and underwent endoscopic papillectomy of major duodenal papilla neoplasms from January 2014 to January 2020 were retrospectively studied, their postoperative outcomes and complication were also analyzed. Tweenty-one patients were successfully performed endoscopic papillectomy of major duodenal papilla neoplasms. Read More

Trauma Surg Acute Care Open 2021 4;6(1):e000570. Epub 2021 Mar 4.

Department of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Even though an acute care surgery (ACS) model has been implemented worldwide, there are still relatively few studies on its efficacy in developing countries, which often have limited capacity and resources. To evaluate ACS efficacy in a developin country, we compared mortality rates and intervention timeliness at a tertiary care center in Thailand among patients with an upper gastrointestinal hemorrhage (UGIH).

Methods: This retrospective study compared two 24-month periods between pre-ACS and post-ACS implementations from July 1, 2014, to June 30, 2018. Read More

JAMA Oncol 2021 May;7(5):735-738

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York.

Importance: Surgical resection has been considered the only curative option for patients with pancreatic cancer. Nonoperative local treatment options that can provide a similar benefit are needed. Emerging radiation techniques that address organ motion have enabled curative radiation doses to be given in patients with inoperable disease. Read More

J Nippon Med Sch 2021 ;88(1):17-24

Department of Gastroenterology and Hepatology, Nippon Medical School Hospital.

With advancements in the development of flexible endoscopes and endoscopic devices and the increased demand for minimally invasive treatments, the indications of therapeutic endoscopy have been expanded. Methods of endoscopic treatment used for tissue removal, hemostasis, and dilatation are as follows. Endoscopic submucosal dissection (ESD) is considered the gold standard curative method for removal of gastrointestinal node-negative neoplasms, regardless of their size or the presence of ulcer formation. Read More

BMC Gastroenterol 2021 Mar 6;21(1):113. Epub 2021 Mar 6.

Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, Korea.

Background: Risk stratification before endoscopy is crucial for proper management of patients suspected as having upper gastrointestinal bleeding (UGIB). There is no consensus regarding the role of nasogastric lavage for risk stratification. In this study, we investigated the usefulness of nasogastric lavage to identify patients with UGIB requiring endoscopic examination. Read More

Chirurgia (Bucur) 2021 Jan-Feb;116(1):89-101

The aim of our study was to explore the feasibility of a novel fluorescence-guided laparoscopic technique to localize the obscure GI haemorrhage, using the vascular wash-out properties of indocyanine green (ICG). Method: The feasability study included patients with previous surgical modifications of the gut architecture, qualified as an overt obscure GI bleeding with an urgent need to be localized and controlled. Five mL of ICG was injected intravenously and laparoscopic infrared inspection was performed 30 minutes after the dye was eliminated from the bloodstream. Read More

BMJ Open Gastroenterol 2021 02;8(1)

Department of Gastroenterology, Newcastle upon Tyne hospitals NHS Trust, Newcastle upon Tyne, UK.

Background: Although evidence suggests frequent gastrointestinal (GI) involvement during coronavirus disease 2019 (COVID-19), endoscopic findings are scarcely reported.

Aims: We aimed at registering endoscopic abnormalities and potentially associated risk factors among patients with COVID-19.

Methods: All consecutive patients with COVID-19 undergoing endoscopy in 16 institutions from high-prevalence regions were enrolled. Read More