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Ulster Med J 2022 May 15;91(2):95-97. Epub 2022 Jun 15.

Consultant Gastroenterologist, Daisy Hill.

A female in her 80's presented to our Emergency Department following a fall. She reported general malaise, weight loss and raised inflammatory markers. Background included renal cell carcinoma 21 years previous, managed with radical nephrectomy. Read More

World J Gastroenterol 2022 May;28(20):2243-2247

Gastroenterology and Endoscopy Unit, Ospedale G. Mazzini, Teramo 64100, Italy.

Background: Intramural duodenal hematoma is a rare condition described for the first time in 1838. This condition is usually associated with blunt abdominal trauma in children. Other non-traumatic risk factors for spontaneous duodenal haematoma include several pancreatic diseases, coagulation disorders, malignancy, collagenosis, peptic ulcers, vasculitis and upper endoscopy procedures. Read More

World J Surg Oncol 2022 Jun 16;20(1):205. Epub 2022 Jun 16.

Department of Gastroenterology and Hepatology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Background: Testicular tumor is one of the common solid tumors in young men. Testicular choriocarcinoma is a non-spermatogonial germ cell tumor, which is the rarest of all testicular cancers. Choriocarcinoma usually shows bleeding at the metastatic site, while gastrointestinal involvement is rare. Read More

Arch Bronconeumol 2021 Jul 21;57(7):498. Epub 2021 May 21.

Servicio de Neumología, Hospital Universitario 12 de Octubre, Madrid, Spain.

Trials 2022 Jun 13;23(1):491. Epub 2022 Jun 13.

Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, China.

Background: Endoscopic submucosal dissection (ESD) is widely used as an effective treatment of early gastric and esophageal tumors, as it is minimally invasive, safe, and convenient. Epigastric pain is a common complication of ESD. In the traditional cognition, the postoperative pain of ESD is not serious and does not attach too much attention. Read More

Surg Laparosc Endosc Percutan Tech 2022 Jun 1;32(3):404-408. Epub 2022 Jun 1.

Division of GI, Trauma, and Endocrine Surgery, Department of Surgery.

Introduction: Data is limited on hybrid transoral incisionless fundoplication (TIF) and hiatal hernia repair in giant paraoesophageal hernia (GPEH). We aimed to assess the safety, patient satisfaction, and symptom resolution following a hybrid paraoesophageal hernia (PEH) repair and TIF in patients with GPEH.

Patients And Methods: All single-session hybrid TIF combined with minimally invasive PEH repair performed between February 2020 and June 2021 were evaluated. Read More

Sichuan Da Xue Xue Bao Yi Xue Ban 2022 May;53(3):404-408

Department of Gastroenterology, West China Hospital, Sichuan Univeristy, Chengdu 610041, China.

Objective: To summarize the clinical characteristics and treatment experience of gastric primary lymphoma with acute upper gastrointestinal bleeding as the primary manifestation, and to provide support for clinical treatment.

Methods: Information on gastric primary lymphoma patients admitted to the Department of Gastroenterology, West China Hospital of Sichuan University between January 2010 and March 2021 for acute upper gastrointestinal bleeding was retrospectively collected. Data on endoscopic morphology, tumor staging, pathology typing, severity of bleeding, risks of rebleeding, treatment and inhospital prognosis were documented and analyzed. Read More

Sichuan Da Xue Xue Bao Yi Xue Ban 2022 May;53(3):375-380

Department of Gastroenterology, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.

Non-variceal upper gastrointestinal bleeding (NVUGIB) is defined as bleeding proximal to the ligament of Treitz in the absence of varices. As a common clinical problem, NVUGIB entails a heavy burden on the healthcare system. In addition to endoscopic hemostasis, evaluation and treatment before and after endoscopy are also of critical importance for the clinical management of NVUGIB patients. Read More

Sichuan Da Xue Xue Bao Yi Xue Ban 2022 May;53(3):361-366

Department of Gastroenterology and Sichuan University-University of Oxford Huaxi Joint Centre for Gastrointestinal Cancer, West China Hospital, Sichuan University, Chengdu 610041, China.

Upper gastrointestinal bleeding (UGIB), a common medical emergency, causes significant morbidity and mortality. Endoscopic evaluation and treatment remain the standard care in patients who can be hemodynamically stabilized. However, severe bleeding despite conservative medication treatment or medication combined with endoscopic intervention occurs in 5%-10% of patients, requiring interventional or surgical treatment. Read More

JNMA J Nepal Med Assoc 2022 Apr 15;60(248):360-363. Epub 2022 Apr 15.

Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.

Introduction: Upper gastrointestinal bleeding is a common medical emergency with significant morbidity and mortality. Its causes can be classified under variceal bleeding or non-variceal bleeding. Peptic ulcer and variceal bleeding are common causes. Read More

Ann Med Surg (Lond) 2022 Jun 13;78:103778. Epub 2022 May 13.

General Surgery Department, La Rabta Hospital Tunis, Tunisia.

Introduction: Non-variceal upper gastrointestinal hemorrhage (NVUGIH) often leads to systematic hospitalization and emergency endoscopy. However, in most cases, it does not constitute an immediate life threat. This study aimed to evaluate the Glasgow-Blatchford Score (GBS) in predicting the need for transfusions, and/or endoscopic or surgical treatments. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2022 May;25(5):447-453

Department of Gastric Surgery, Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital) , Hangzhou 310022, China.

To investigate the functional outcomes and postoperative complications of Cheng's GIRAFFE reconstruction after proximal gastrectomy. A descriptive case series study was conducted. Clinical data of 100 patients with adenocarcinoma of the esophagogastric junction who underwent Cheng's GIRAFFE reconstruction after proximal gastrectomy in Cancer Hospital of University of Chinese Academy of Sciences (64 cases), Zhejiang Provincial Hospital of Chinese Medicine (24 cases), Lishui Central Hospital (10 cases), Huzhou Central Hospital (1 case) and Ningbo Lihuili Hospital (1 case) from September 2017 to June 2021 were retrospectively analyzed. Read More

Zhonghua Wei Chang Wai Ke Za Zhi 2022 May;25(5):440-446

Department of General Surgery, First Medical Center, Chinese PLA General Hospital, Beijing 100853, China.

To explore the feasibility and preliminary technical experience of the double-tract reconstruction combined with π-shaped esophagojejunal anastomosis after total laparoscopic proximal gastrectomy (TLPG) in the treatment of adenocarcinoma of esophagogastric junction (AEG). A descriptive case series study method was used. Clinical data of 12 AEG patients who underwent the double-tract reconstruction combined with π-shaped esophagojejunal anastomosis after TLPG from January 2021 to June 2021 at the Department of General Surgery, First Medical Center, PLA General Hospital were retrospectively analyzed. Read More

BMJ Case Rep 2022 May 19;15(5). Epub 2022 May 19.

Department of Medicine, Zayed Military Hospital, Abu Dhabi, UAE.

While gastrointestinal (GI) tuberculosis (TB) accounts for 1%-3% of all TB cases worldwide, TB of the stomach is extremely rare and accounts for 1%-2% of all GI TB. Little is known about this entity, and most data are obtained from case reports. We report a case of a woman in her 60s who presented with a 2-week history of generalised weakness, fatigue and shivering, with severe loss of appetite on background history of dyspepsia and significant weight loss for the preceding 2 years. Read More

World J Gastroenterol 2022 Apr;28(14):1455-1478

Section of Hepatobiliary-Pancreatic and GI Surgery, Washington University St. Louis, St. Louis, MO 63110, United States.

Background: Heterotopic pancreas (HP) is an aberrant anatomic malformation that occurs most commonly in the upper gastrointestinal tract. While the majority of heterotopic pancreatic lesions are asymptomatic, many manifest severe clinical symptoms which require surgical or endoscopic intervention. Understanding of the clinical manifestations and symptoms of HP is limited due to the lack of large volume studies in the literature. Read More

Clin Endosc 2022 May 28;55(3):339-346. Epub 2022 Apr 28.

Gastroenterology and Digestive Endoscopy Unit, General Hospital, Perugia, Italy.

Since the earliest reports, advanced clipping systems have been developed, and it is possible to choose among many models with different structural and technical features. The main drawback of through-the-scope clips is their small size, which allows the compression of limited amounts of tissue needed for large-size vessel treatment. Therefore, the over-the-scope clip system was realized, allowing a larger and stronger mechanical compression of large tissue areas, with excellent results in achieving a definitive hemostasis in difficult cases. Read More

BMC Gastroenterol 2022 May 9;22(1):226. Epub 2022 May 9.

Department of Hepatobiliary Surgery, Dongyang People's Hospital, Zhejiang Province, Jinhua, 322100, China.

Background: Primary duodenal cancer (PDC) is rare, especially signet-ring cell carcinoma (SRCC) of the duodenal bulb, and it is commonly misdiagnosed as an ulceration. Here, we report a rare case of SRCC of the duodenal bulb presenting with gastrointestinal hemorrhage in an 82-year-old man.

Case Presentation: An 82-year-old man was admitted for gastrointestinal hemorrhage. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2022 Apr;24(4):372-376

Department of Pediatric Gastroenterology, Shengjing Hospital Affiliated to China Medical University, Shenyang 110000, China.

Objectives: To study the clinical manifestations and gastroscopic characteristics of upper gastrointestinal ulcer in children.

Methods: A retrospective analysis was performed for the children who underwent gastroscopy and were found to have upper gastrointestinal ulcer for the first time at the Endoscopy Center of Shengjing Hospital, China Medical University, from January 2011 to May 2021. According to the cause of the disease, they were divided into primary ulcer group (primary group; =148) and secondary ulcer group (secondary group; =25). Read More

FP Essent 2022 May;516:11-16

University of Kansas School of Medicine-Wichita, 1010 North Kansas, Wichita, KS 67214-3199.

Occult gastrointestinal (GI) bleeding is bleeding from the GI tract that is not noticeable to patients or physicians. Patients with unexplained anemia (ie, not attributable to another cause such as menstrual bleeding), particularly iron deficiency anemia, should be evaluated for occult GI bleeding. Similarly, if fecal blood is detected during routine colorectal cancer screening, an evaluation for occult bleeding is indicated. Read More

Tech Coloproctol 2022 Jul 2;26(7):545-550. Epub 2022 May 2.

Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic Florida, Weston, FL, USA.

Background: Endoscopic mucosal resection (EMR) is the primary treatment modality for superficial gastrointestinal mucosal lesions > 2 cm. However, the procedure carries some risk of complications including bleeding, perforation, and local recurrence. This study aimed to examine factors associated with EMR outcomes, especially in terms of local recurrence. Read More

Rinsho Ketsueki 2022 ;63(4):265-270

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center.

A 73-year-old woman was hospitalized with sudden chest pain and hematemesis. Chest computed tomography and upper gastrointestinal endoscopy revealed an idiopathic submucosal hematoma from the cervical esophagus to the esophagogastric mucosal junction. Idiopathic esophageal submucosal hematoma is often prone to a bleeding tendency of an underlying disorder. Read More

Cir Pediatr 2022 Apr 1;35(2):57-62. Epub 2022 Apr 1.

La Fe University and Polytechnic Hospital. Valencia (Spain).

Introduction: Transjugular intrahepatic portosystemic shunt (TIPS) was designed to treat complications of portal hypertension (PH). The objective of this study was to analyze the results of the TIPS performed in pediatric patients in our institution as a previous step to liver transplantation (LT).

Material And Methods: A retrospective, descriptive study of pediatric patients with liver cirrhosis undergoing TIPS prior to LT from 2015 to 2020 was carried out. Read More

Pediatr Emerg Care 2022 May 23;38(5):e1245-e1250. Epub 2021 Dec 23.

Division of Neurogastroenterology and Motility, Department of Paediatric Gastroenterology, UCL Institute of Child Health and Great Ormond Street Hospital, London, United Kingdom.

Objectives: Infantile acute upper gastrointestinal bleeding involves a decision for therapeutic intervention that most pediatricians first coming into contact with the patient are, not unreasonably, unable to objectively provide. Therefore, some objective tools of individual risk assessment would seem to be crucial. The principal aim of the present study was to investigate the anamnestic and clinical parameters of infants with hematemesis, together with laboratory and instrumental findings, to create a scoring system that may help identify those infants requiring an appropriate and timely application of upper gastrointestinal (GI) endoscopy. Read More

Sci Rep 2022 04 27;12(1):6833. Epub 2022 Apr 27.

Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea.

The optimal timing of endoscopy in patients with acute upper gastrointestinal bleeding (UGIB) remains controversial. In this study, we investigated the clinical outcomes of urgent endoscopy in patients with UGIB compared with elective endoscopy. From January 2016 to December 2018, consecutive patients who visited the emergency department and underwent endoscopy for clinical manifestations of acute UGIB, including variceal bleeding, were eligible. Read More

Korean J Gastroenterol 2022 04;79(4):177-181

Department of Surgery, Inje University Haeundae Paik Hospital, Inje University College of Medicine, Busan, Korea.

Malignant gastrointestinal stromal tumors (GISTs) are rare neoplasms originating from the gastrointestinal tract that rarely occur in patients below 40 years of age. To our knowledge, there have been no previous reports of satellite and metastatic nodules in GIST. We present a case of a young patient with a huge malignant gastric GIST accompanied by spontaneous bleeding and satellite and metastatic nodules, successfully treated surgically, without preoperative chemotherapy administration. Read More

Curr Oncol 2022 03 30;29(4):2472-2482. Epub 2022 Mar 30.

Department of Vascular Surgery, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 12203 Berlin, Germany.

Purpose: To report and compare the results of endovascular and open surgical treatment for erosion bleeding of visceral arteries following pancreatitis and pancreatic surgery.

Materials And Methods: This retrospective study included 65 consecutive patients (46 males, mean age 63 ± 14 years) presenting with visceral artery erosions between January 2011 and December 2020. Endpoints were technical success, freedom from reintervention, stent-graft-related complications, and 30-day and one-year mortality. Read More

BMC Gastroenterol 2022 Apr 20;22(1):194. Epub 2022 Apr 20.

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, National Clinical Research Center for Digestive Diseases, Beijing Digestive Disease Center, Faculty of Gastroenterology of Capital Medical University, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Beijing, 100050, China.

Background: Delayed bleeding is an important adverse event after gastric endoscopic submucosal dissection (ESD). We aimed to externally validate the Bleeding after ESD Trend from Japan (BEST-J) score and subsequently develop a risk prediction model for bleeding in Chinese patients with early gastric cancer (EGC) after ESD.

Methods: The clinical data of patients who underwent ESD for EGC in Beijing Friendship Hospital from June 2013 to December 2019 were collected retrospectively. Read More

J Assoc Physicians India 2022 Apr;70(4):11-12

Vmmc and Sjh, New Delhi.

Esophageal variceal bleeding remains the leading cause of acute mortality in patients with cirrhosis. As per guidelines, upper gastrointestinal screening endoscopy is recommended for all patients with cirrhosis to rule out esophageal varices. However, only 50% of newly diagnosed patients with cirrhosis have Esophageal varices. Read More

J Assoc Physicians India 2022 Apr;70(4):11-12

Care Hospitals, Nampally, Hyderabad.

Acute upper gastrointestinal bleeding (UGIB) is a common emergency and can be a serious condition that requires hospitalization, rapid evaluation and management. The usual presentation is hematemesis (vomiting of blood or coffee ground-like material) and/or melena (black, tarry stools) 1. UGIB occurs more commonly in men and older subjects. Read More

Arq Gastroenterol 2022 Jan-Mar;59(1):157-158

Hospital 9 de Julho, Departamento de Endoscopia Gastrointestinal, São Paulo, SP, Brasil.