208,224 results match your criteria Upper GI Tract


Type II enteropathy-associated T cell lymphoma in the duodenum: A rare case report.

Medicine (Baltimore) 2020 Jun;99(23):e20050

Department of Gastroenterological Surgery.

Introduction: Enteropathy-associated T-cell lymphoma (EATL) is a very rare form of lymphoma in the gastrointestinal tract. The proximal jejunum and ileum are the most common sites of EATL, whereas EATL rarely arises in the duodenum, and EATL involving metastasis of the bilateral ovaries is even rarer.

Patient Concerns: A 43-year-old female suffered from upper abdominal pain and weight loss for 3 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000020050DOI Listing

An Unusual Cause of Lower Gastrointestinal Bleeding: Cecal Dieulafoy's Lesion.

Cureus 2020 May 2;12(5):e7928. Epub 2020 May 2.

Internal Medicine: Gastroenterology, Tufts Medical Center, Boston, USA.

Colonic Dieulafoy's lesions are an exceptionally rare cause of lower gastrointestinal (GI) bleeding. These lesions are almost exclusively found in the upper GI tract based on previous reviews. We present a case of an 81-year-old man who presented with melena progressing to hematochezia and was found to have a cecal Dieulafoy's lesion on colonoscopy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7928DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265779PMC

Endoscopic Management of Clinically Severe Obesity: Primary and Secondary Therapeutic Procedures.

Curr Obes Rep 2020 Jun 3. Epub 2020 Jun 3.

Department of Gastroenterology, Mayo Clinic Rochester, Rochester, MA, USA.

Purpose Of Review: In the treatment of epidemic obesity and metabolic disorders, conservative approaches often fail to achieve the treatment goal in patients with very high BMI. To date, bariatric surgery accomplishes the most sustainable results in patients with morbid obesity. This leads to a treatment gap for lower and middle classes of obesity defined by BMI. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s13679-020-00385-yDOI Listing

Dysphagia as an Initial Manifestation of Eosinophilic Esophagitis.

Cureus 2020 Apr 30;12(4):e7898. Epub 2020 Apr 30.

Hematology and Oncology, Ashland Bellefonte Cancer Center, Ashland, USA.

Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7759/cureus.7898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263406PMC

Efficacy and Safety of Evocalcet Evaluated by Dialysate Calcium Concentration in Patients with Secondary Hyperparathyroidism Undergoing Hemodialysis.

Int J Nephrol Renovasc Dis 2020 12;13:97-106. Epub 2020 May 12.

Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

Purpose: Evocalcet is a novel oral calcimimetic drug that has demonstrated similar efficacy to cinacalcet in regulating serum parathyroid hormone (PTH), calcium, and phosphate levels, with fewer upper gastrointestinal tract-related adverse drug reactions (ADRs) in patients with secondary hyperparathyroidism undergoing hemodialysis in Japan. We investigated the efficacy and safety of once-daily oral evocalcet under different dialysate calcium concentrations.

Patients And Methods: A post hoc analysis by dialysate calcium concentration (2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/IJNRD.S243210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229806PMC

Enteral versus parenteral nutrition in the conservative treatment of upper gastrointestinal fistula after surgery: a multicenter, randomized, parallel-group, open-label, phase III study (NUTRILEAK study).

Trials 2020 Jun 2;21(1):448. Epub 2020 Jun 2.

Department of Digestive and Oncological Surgery, Lille University Hospital, Lille, France.

Background: Postoperative upper gastrointestinal fistula (PUGIF) is a devastating complication, leading to high mortality (reaching up to 80%), increased length of hospital stay, reduced health-related quality of life and increased health costs. Nutritional support is a key component of therapy in such cases, which is related to the high prevalence of malnutrition. In the prophylactic setting, enteral nutrition (EN) is associated with a shorter hospital stay, a lower incidence of severe infectious complications, lower severity of complications and decreased cost compared to total parenteral nutrition (TPN) following major upper gastrointestinal (GI) surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13063-020-04366-3DOI Listing

[Solitary Langerhans cell histiocytosis of the stomach: report of a case].

Zhonghua Bing Li Xue Za Zhi 2020 Jun;49(6):631-633

Department of Pathology, the Affiliated Hospital of Qingdao University, Qingdao 266003, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112151-20191008-00545DOI Listing

Experience with Esophago-Gastro-Intestinal Transit Scintigraphy - Initial 229 patients: Multiple Regions of Dysmotility are Common.

J Nucl Med 2020 Jun 1. Epub 2020 Jun 1.

Johns Hopkins University, United States.

The purpose of this investigation was to review our experience with our "Comprehensive Gastrointestinal Transit Study" in the first 229 patients. This scintigraphic study analyzes motility of the entire gut, from esophagus through the rectosigmoid colon. Data were reviewed for our first two years of experience (184 females, 45 males), age 20-79 (mean 44±16) with this exam. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.120.243527DOI Listing

Tailoring assembly behavior of starches to control insulin release from layer-by-layer assembled colloidal particles.

Int J Biol Macromol 2020 May 29. Epub 2020 May 29.

Teagasc Food Research Centre, Moorepark, Fermoy, Co. Cork, Ireland.

Self-assembly behavior of charged-starches significantly influenced core-shell structures of layer-by-layer assembled particles. In this study, insulin (IN)-loaded nanoparticles with structured shell features were fabricated to investigate how the interactions of carboxymethyl starch (CMS) with spermine-modified starch (SS) influenced IN release properties of the particles (IN/CMS/SS/CMS) within the gastrointestinal tract (GIT). Results indicated that the assembly action of CMS and SS could be controlled by simply tailoring the ratio of CMS/SS content. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijbiomac.2020.05.237DOI Listing

Quality indicators in diagnostic upper gastrointestinal endoscopy.

Therap Adv Gastroenterol 2020 15;13:1756284820916693. Epub 2020 May 15.

Department of Gastroenterological Oncology, the Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.

Upper gastrointestinal (UGI) endoscopy contributes a major clinical service with consistently growing demand around the world. Its utility corresponds to varying epidemiological issues throughout the globe, with cancer screening and surveillance being of the utmost priority. Despite high accuracy in neoplasia detection, UGI endoscopy remains a highly operator-dependent procedure, characterized by a substantial rate of missed pathology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1756284820916693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232050PMC

Optical Biopsy of the Upper GI Tract Using Fluorescence Lifetime and Spectra.

Front Physiol 2020 13;11:339. Epub 2020 May 13.

School of Biomedical Engineering, Faculty of Engineering, McMaster University, Hamilton, ON, Canada.

Screening and surveillance for gastrointestinal (GI) cancers by endoscope guided biopsy is invasive, time consuming, and has the potential for sampling error. Tissue endogenous fluorescence spectra contain biochemical and physiological information, which may enable real-time, objective diagnosis. We first briefly reviewed optical biopsy modalities for GI cancer diagnosis with a focus on fluorescence-based techniques. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphys.2020.00339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237753PMC

Successful endoscopic treatment of a large impacted gallstone in the duodenum using laser lithotripsy, Bouveret's syndrome: A case report.

World J Gastroenterol 2020 May;26(19):2458-2463

Department of Gastroenterology, Franciscus Gasthuis & Vlietland, Rotterdam 3045 PM, Zuid-Holland, Netherlands.

Background: Bouveret´s syndrome is defined as a gastric outlet obstruction after passage of a gallstone through a fistula into the duodenum. Due to its rarity, the diagnosis of Bouveret's syndrome is often delayed and causes a high morbidity and mortality rate.

Case Summary: A 93-year-old female presented with worsening pain in the right upper abdomen and vomiting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3748/wjg.v26.i19.2458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243648PMC

Pharmacokinetics of imipenem in both plasma and peritoneal draining liquid in elder patients with perforated upper gastrointestinal tract.

Eur J Clin Pharmacol 2020 May 30. Epub 2020 May 30.

Department of Emergency Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu, 233004, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00228-020-02904-1DOI Listing

Ergothioneine, a metabolite of the gut bacterium Lactobacillus reuteri, protects against stress-induced sleep disturbances.

Transl Psychiatry 2020 May 28;10(1):170. Epub 2020 May 28.

Affective Disorders Research Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan.

The relationships between depression and gut microbiota, particularly those involving the immune system, have become a major focus of recent research. Here, we analyzed changes in gut microbiota and their sulfur metabolites in the feces of a depression rat model using the modified 14-day social defeat stress (SDS) paradigm. Our results showed that SDS increased fecal Lactobacillus reuteri in correlation with ergothioneine levels at around day 11, which continued for at least 1 month following SDS administration. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41398-020-0855-1DOI Listing

Anthocyanins: New techniques and challenges in microencapsulation.

Food Res Int 2020 Jul 11;133:109092. Epub 2020 Feb 11.

School of Food Engineering, University of Campinas - UNICAMP, 13083-862 Campinas, SP, Brazil. Electronic address:

Anthocyanins are a bioactive compound belonging to the flavonoid classthatis present in human nutrition through plant-based foods. Due to their antioxidant properties, several health benefits related to their consumption are reported in the literature. The stability of the color and the properties of anthocyanins is strongly affected by pH, solvent, temperature, and other environmental conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.foodres.2020.109092DOI Listing

The effect of reduced gastric acid secretion on the gastrointestinal disposition of a ritonavir amorphous solid dispersion in fasted healthy volunteers: an in vivo - in vitro investigation.

Eur J Pharm Sci 2020 May 24:105377. Epub 2020 May 24.

Drug Delivery and Disposition, KU Leuven, Gasthuisberg O&N II, Herestraat 49 - box 921, 3000 Leuven, Belgium. Electronic address:

This paper summarizes efforts to (i) better understand the behavior of amorphous solid dispersions (ASDs) under real-life dosing conditions and (ii) evaluate the capability of in vitro methodologies to capture gastro-intestinal drug disposition. In a first part of the study, five healthy volunteers participated in a two-way crossover trial in which one Norvir® tablet (100 mg ritonavir) was dosed under fasted and fasted + PPI conditions. Gastrointestinal aspirates were collected from both the stomach and duodenum as a function of time to map the gastrointestinal drug disposition of the ritonavir ASD formulation and to evaluate the impact of reduced gastric acid secretion on formulation performance. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejps.2020.105377DOI Listing

[Human infection in esophagus: a case report].

Authors:
Q Q Zhang

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2020 Mar;32(2):217-218

Department of Laboratory Medicine, Tengzhou Central People's Hospital Affiliated to Xuzhou Medical University, Shandong Province, Tengzhou 277500, China.

This paper reports a female patient with Gongylonema pulchrum parasitizing in the esophagus, with aims to call for the attention to the role of parasite detection in the diagnosis of human diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.16250/j.32.1374.2019289DOI Listing

Assessment of pediatric Crohn's disease activity: validation of the magnetic resonance enterography global score (MEGS) against endoscopic activity score (SES-CD).

Abdom Radiol (NY) 2020 May 26. Epub 2020 May 26.

Department of Pathology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.

Objective: The aim of this study is to evaluate the ability of magnetic resonance enterography global score (MEGS) to diagnose the activity of pediatric Crohn's disease (CD) and its correlation with endoscopic activity score.

Materials And Methods: 70 pediatric CD patients (between the ages of 6 and 17) were enrolled who underwent ileocolonoscopy and magnetic resonance enterography (MRE) within 7 days. The simplified endoscopic activity score for Crohn's disease (SES-CD) and MEGS were acquired in the terminal ileum. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-020-02590-8DOI Listing

Segmental Hepatic Steatosis Due to Portal Vein Stricture After Pediatric Living Donor Liver Transplantation: A Case Report.

Transplant Proc 2020 May 23. Epub 2020 May 23.

Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Background And Objective: Liver transplantation (LT) is the gold-standard treatment for end-stage liver disease; however, late-onset complications such as fatty liver can occur in the absence of metabolic comorbidities. We report a unique case of post-transplant hepatic steatosis developing in only a part of the liver graft.

Case Report: A 1-year-old boy underwent ABO-incompatible living donor liver transplantation (LDLT) with a left lateral liver graft donated from his mother for biliary atresia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.transproceed.2020.01.149DOI Listing

[Acupoint catgut embedding improves gastric mucosal injury by down-regulating expression of HIF-1α and VEGF in chronic atrophic gastritis rats].

Zhen Ci Yan Jiu 2020 May;45(5):384-8

Renhe Chinese Medicine Hospital, Foshan 528244, Guangdong Province.

Objective: To observe the effect of acupoint catgut embedding on histopathological changes of gastric mucosa and expression of mucosal hypoxia inducible factor (HIF)-1α and vascular endothelial growth factor (VEGF) proteins in chronic atrophic gastritis (CAG) rats, so as to explore its mechanisms underlying improvement of CAG.

Methods: Male SD rats were divided into blank group (=10) and model group (=9) and catgut embedment group (=10). The CAG model was established by free drinking of N-methyl-N'-nitro-N-nitroso-guanidine solution (100 μg/mL) and irregular diet. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.13702/j.1000-0607.190189DOI Listing

Esophageal variceal hemorrhage: the role of MDCT characteristics in predicting the presence of varices and bleeding risk.

Abdom Radiol (NY) 2020 May 23. Epub 2020 May 23.

Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center (ADIR), Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: To investigate the associated Multi-Detector Computed Tomography (MDCT) features for esophageal varices (EVs) and esophageal variceal hemorrhage (EVH), with particular emphasis on different collateral veins.

Materials And Methods: All cirrhotic patients who had undergone both Upper Gastrointestinal Tract (UGIT) endoscopy and contrast-enhanced MDCT within 6 months from 2013 to 2019 were included in the study. MDCT of 124 patients, 76 males and 48 females, aged between 21 and 73 years old were evaluated for presence of EV and presence and size of different collaterals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00261-020-02585-5DOI Listing

An Unusual Dysphagia for Solids in a 17-Year-Old Girl Due To a Lusoria Artery: A Case Report and Review of the Literature.

Int J Environ Res Public Health 2020 May 20;17(10). Epub 2020 May 20.

Paediatric Clinic, Pietro Barilla Children's Hospital, Department of Medicine and Surgery, University of Parma, 43121 Parma, Italy.

Dysphagia is a condition that can have many underlying causes, often different between adults and children and its early diagnosis is crucial especially during childhood and adolescence, given the importance of proper nutritional intake to ensure adequate growth and development. We described the case of a 17-year-old girl reporting dysphagia for solids for approximately one month. No symptoms were previously referred. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijerph17103581DOI Listing

Clinical and Epidemiological Features of a Family Cluster of Symptomatic and Asymptomatic SARS-CoV-2 Infection.

J Pediatric Infect Dis Soc 2020 May 22. Epub 2020 May 22.

German Center for Infection Research, Munich Partner Site.

This report describes the clinical and virological characteristics of three children in a family cluster experiencing infection with SARS-CoV2. While the youngest child was not infected, both parents and the two 2- and 5 years-old children became infected. The children were only briefly symptomatic with predominant gastrointestinal symptoms. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jpids/piaa060DOI Listing

Neonatal Aerodigestive Disorders: Epidemiology and Economic Burden.

Clin Perinatol 2020 Jun 19;47(2):211-222. Epub 2020 Feb 19.

Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Division of Neonatology, Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA; Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA. Electronic address:

Aerodigestive disorders, those affecting the upper and lower airway or upper gastrointestinal tract, are interrelated anatomically during fetal development and functionally after birth. Successful respiration and feeding requires careful coordination to promote effective swallowing and prevent aspiration. I describe the epidemiology, including the prevalence of the most common aerodigestive disorders. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clp.2020.02.003DOI Listing

Primary extramedullary plasmacytoma of the eyelid conjunctiva - A case report and review of the literature.

Ann Med Surg (Lond) 2020 Jul 7;55:1-4. Epub 2020 May 7.

Ophthalmology Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Extramedullary plasmacytomas (EMPs) are uncommon plasma cell tumors that develop in soft tissue as isolated tumors without osseous involvement while secondary lesions are associated with systemic multiple myeloma (MM). Primary extramedullary lesions are most commonly found in upper respiratory tract, gastrointestinal tract and lymph nodes. They can be found either in patients with history of MM or preceding the manifestation of a systemic disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.amsu.2020.04.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229271PMC

A randomized Controlled Trial of Different Young Child Formulas on Upper Respiratory and Gastrointestinal Tract Infections in Chinese Toddlers.

Pediatr Allergy Immunol 2020 May 19. Epub 2020 May 19.

FrieslandCampina, Amersfoort, the Netherlands.

Background: Bioactive proteins and human milk oligosaccharides (HMOs), important ingredients in breastmilk, that protect against infections are lacking in young child formula (YCF). This study investigated the effects of new YCFs on respiratory and gastrointestinal infections in toddlers.

Methods: 461 healthy Chinese children aged 1-2. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pai.13276DOI Listing

Advances in Oral Drug Delivery for Regional Targeting in the Gastrointestinal Tract - Influence of Physiological, Pathophysiological and Pharmaceutical Factors.

Authors:
Susan Hua

Front Pharmacol 2020 28;11:524. Epub 2020 Apr 28.

Therapeutic Targeting Research Group, School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, NSW, Australia.

The oral route is by far the most common route of drug administration in the gastrointestinal tract and can be used for both systemic drug delivery and for treating local gastrointestinal diseases. It is the most preferred route by patients, due to its advantages, such as ease of use, non-invasiveness, and convenience for self-administration. Formulations can also be designed to enhance drug delivery to specific regions in the upper or lower gastrointestinal tract. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fphar.2020.00524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212533PMC

Peritoneal carcinomatosis of unknown primary site, a study of 25 patients over 30 years.

Eur J Surg Oncol 2020 Apr 28. Epub 2020 Apr 28.

Program in Peritoneal Surface Malignancies, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address:

Introduction: Peritoneal carcinomatosis may be diagnosed by cytology or CT-guided biopsy, but routine radiologic and endoscopic workup not reveal a primary site. The clinical condition is referred to as peritoneal carcinomatosis of unknown primary site.

Methods: Over a 30-year time interval all patients treated with an initial diagnosis of carcinomatosis of unknown primary site were managed on a special clinical pathway. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejso.2020.03.217DOI Listing

An unusual cause of upper gastrointestinal bleeding due to recurrent hepatocellular carcinoma: A case report.

Int J Surg Case Rep 2020 11;70:83-86. Epub 2020 May 11.

Department of Surgery, The Chinese University of Hong Kong, Hong Kong.

Introduction: Upper gastrointestinal bleeding (UGIB) in patients suffering from hepatocellular carcinoma (HCC) is usually due to oesophageal or gastric varices secondary to portal hypertension. Very rarely, HCC can directly invade into the stomach or duodenum resulting in UGIB.

Presentation Of Case: A 62-year-old man presented to the emergency department for haematemesis and tarry stool. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijscr.2020.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226638PMC

Innovative Therapeutic Endoscopy in the Upper Gastrointestinal Tract: A Review of the JGES Core Sessions.

Dig Endosc 2020 May 16. Epub 2020 May 16.

Digestive Diseases Center, Showa University Koto-Toyosu Hospital, Tokyo, Japan.

Workshops on "Innovative Therapeutic Endoscopy" for upper gastrointestinal tract diseases were held four times as the Japan Gastroenterological Endoscopic Society (JGES) Core Sessions at the 93rd to 96th Biannual Meetings of the JGES. A total of 48 research presentations (including 2 invited lectures) were reported , and various discussions were held on these topics. When the research presentations were categorized according to the therapeutic procedure, endoscopic submucosal dissection (ESD) was the most frequent with 28 presentations (58. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/den.13722DOI Listing

Infections are associated with increased risk of giant cell arteritis - a population-based case-control study from Southern Sweden.

J Rheumatol 2020 May 15. Epub 2020 May 15.

From the Department of Clinical Sciences, Rheumatology, Lund University, Helsingborg, Sweden; Department of Clinical Sciences, Clinical Epidemiology Unit, Lund University, Lund, Sweden; Department of Clinical Sciences, Infection Medicine, Lund University, Lund, Sweden; Department of Clinical Sciences, Rheumatology, Lund University, Lund, Sweden; Department of Clinical Sciences Malmö, Rheumatology, Lund University, Malmö, Sweden; Department of Medicine, University of Cambridge, Cambridge, UK. This study was supported by grants from the Swedish Research Council (Vetenskapsrådet - 2019-01655). Address correspondence to Pavlos Stamatis, MD, Department of Internal Medicine, Rheumatology Section, SE-254 37 Helsingborg, Sweden.

Objective: To investigate the association of infections with the subsequent development of giant cell arteritis (GCA) in a large population-based cohort from a defined geographic area in Sweden.

Methods: Patients diagnosed with biopsy-confirmed GCA between 2000 and 2016 were identified through the database of the Department of Pathology in Skåne, the southernmost region of Sweden. For each GCA case, 10 controls matched for age, sex, and area of residence were randomly selected from the general population. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3899/jrheum.200211DOI Listing

Long-Term Outcomes of Pancreas-Sparing Duodenectomy for Duodenal Polyposis in Familial Adenomatous Polyposis Syndrome.

J Gastrointest Surg 2020 May 14. Epub 2020 May 14.

Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A100, Cleveland, OH, 44195, USA.

Background: Pancreas-sparing duodenectomy (PSD) offers definitive therapy for duodenal polyposis associated with familial adenomatous polyposis (FAP). We reviewed the long-term complications of PSD and evaluated the incidence of high-grade dysplasia (HGD) and cancer in the remaining upper gastrointestinal tract.

Methods: Forty-seven FAP patients with duodenal polyposis undergoing PSD from 1992 to 2019 were reviewed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11605-020-04621-7DOI Listing

Follow-up of skin lesions during the evolution of COVID-19: a case report.

Arch Dermatol Res 2020 May 14. Epub 2020 May 14.

Medical Faculty of Recife, Centro de Ciências Médicas, Federal University of Pernambuco, Av. da Engenharia, 531-611 - Cidade Universitária, Recife, 50730-120, PE, Brazil.

The disease caused by the new coronavirus (COVID-19) has many systemic manifestations affecting the upper airways, lungs, gastrointestinal tract and inducing hematological repercussions. With the evolution of the pandemic, skin lesions were observed. However, there is little information about the evolution of the lesions at this moment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00403-020-02091-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221337PMC

[A Case of Gastric Schwannoma Diagnosed Preoperatively].

Gan To Kagaku Ryoho 2020 May;47(5):835-837

Dept. of Surgery, Tokyo Metropolitan Geriatric Medical Center.

The patient was a 52-year-old woman, who was found to have an abnormality in the upper gastrointestinal(UGI)tract, via a contrast-imaging study; she had no symptoms.Computed tomography(CT)revealed a tumor, measuring approximately 100mm in diameter, in the antrum of the stomach.The tumor was diagnosed as gastric schwannoma using endoscopic ultrasonography-guided fine-needle aspiration(EUS-FNA). Read More

View Article

Download full-text PDF

Source

Lasting Symptoms After Esophageal Resection (LASER): European Multicenter Cross-sectional Study.

Ann Surg 2020 May 11. Epub 2020 May 11.

Department Surgery and Cancer, Imperial College London, UK.

Objective: To identify the most prevalent symptoms and those with greatest impact upon health-related quality of life (HRQOL) among esophageal cancer survivors.

Background: Long-term symptom burden after esophagectomy, and associations with HRQOL, are poorly understood.

Patients And Methods: Between 2010 and 2016, patients from 20 European Centers who underwent esophageal cancer surgery, and were disease-free at least 1 year postoperatively were asked to complete LASER, EORTC-QLQ-C30, and QLQ-OG25 questionnaires. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SLA.0000000000003917DOI Listing
May 2020
8.327 Impact Factor

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes.

Sci Immunol 2020 05;5(47)

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA. Key Laboratory of Marine Drugs, Ministry of Education, Ocean University of China, Qingdao, China. Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO, USA. Program in Virology, Harvard Medical School, 200 Longwood Ave, Boston, MA, USA. Department of Medicine, Division of Gastroenterology, Washington School of Medicine, St. Louis, MO, USA. Department of Pathology, Stanford School of Medicine, Stanford, CA, USA. VA Palo Alto Health Care System, Department of Veterans Affairs, Palo Alto, CA, USA. Department of Medicine, Division of Gastroenterology and Hepatology, and Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA, USA. Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.

Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA are frequently observed in COVID-19 patients. However, it is unclear whether SARS-CoV-2 replicates in the human intestine and contributes to possible fecal-oral transmission. Here, we report productive infection of SARS-CoV-2 in ACE2 mature enterocytes in human small intestinal enteroids. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciimmunol.abc3582DOI Listing

[Laparoscopic gastroduodenostomy with manual suture for Billroth Ⅰ anastomosis: a report of 36 cases].

Zhonghua Wai Ke Za Zhi 2020 May;58(5):383-387

Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China.

To examine the clinical efficiency of laparoscopic gastroduodenostomy with BillrothⅠanastomosis with manual suture. The clinic data of 36 patients with gastric cancer who underwent laparoscopic gastroduodenostomy with Billroth Ⅰ anastomosis from November 2017 to September 2019 in Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital were analyzed retrospectively.There were 22 males and 14 females, aged (64. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3760/cma.j.cn112139-20191119-00566DOI Listing

Ulcerative reflux esophagitis associated with Clostridium ventriculi following hiatoplasty - is antibiotic treatment necessary? A case report.

Z Gastroenterol 2020 May 11;58(5):456-460. Epub 2020 May 11.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.

Clostridium (C.) ventriculi (known as Sarcina ventriculi) is a ubiquitous gram-positive, anaerobic, acidophilic coccus found in patients with gastric motility disorders. The microorganisms can be identified histologically by their characteristic presentation in tetrads or packets of 8 in hematoxylin and eosin stains. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/a-1123-7984DOI Listing

Pay More Attention to the Follow-Up of Remnant Stomach.

Am Surg 2020 04;86(4):e219

View Article

Download full-text PDF

Source

Fundectomy as a Modified Technique for One Anastomosis Gastric Bypass.

Authors:
Hung-Chieh Lo

Am Surg 2020 Apr;86(4):e194-e195

View Article

Download full-text PDF

Source

[A Case of Esophageal Neuroendocrine Carcinoma(NEC)Treated with Collective Treatment].

Gan To Kagaku Ryoho 2020 Apr;47(4):722-724

Dept. of Gastroenterological Surgery, Kawasaki Medical School.

A 68-year-old man presented to our hospital. An upper gastrointestinal tract endoscopy performed elsewhere revealed an elevated lesion with a circumferential esophageal cancer(identified as small cell carcinoma). Perthe treatment forsmall cell cancer and the standard treatment for esophageal neuroendocrine carcinoma, 7 courses of CBDCA(5mg/m2)plus ETP (100mg/m2)were administered. Read More

View Article

Download full-text PDF

Source

Clinical remission of ulcerative colitis after different modes of faecal microbiota transplantation: a meta-analysis.

Int J Colorectal Dis 2020 Jun 9;35(6):1025-1034. Epub 2020 May 9.

Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China.

Background: Ulcerative colitis (UC) is a chronic, recurrent and destructive disease of the gastrointestinal tract. Faecal microbiota transplantation (FMT) is a therapeutic measure in which faecal microbiota from healthy people is transplanted into patients.

Aim: To systematically evaluate the safety and effectiveness of treating UC with different modes of FMT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00384-020-03599-7DOI Listing

Anticholinergic, anti-depressant and other medication use is associated with clinically relevant oesophageal manometric abnormalities.

Aliment Pharmacol Ther 2020 Jun 7;51(11):1130-1138. Epub 2020 May 7.

Department of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Background: Medications can affect gastrointestinal tract motility. However, their effects on oesophageal motility in particular are often not as widely known or may be underestimated.

Aim: To review the effect of existing medication use on high-resolution oesophageal manometry (HRM) in a 'real-world' setting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/apt.15758DOI Listing
June 2020
5.727 Impact Factor

A Case Report: Neonatal Torsional Ovarian Cyst.

Sisli Etfal Hastan Tip Bul 2019 26;53(4):430-432. Epub 2019 Nov 26.

Department of Neonatal, Istanbul Health Sciences University, Sariyer Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

The majority of abdominal masses detected in the neonatal period are benign (85%) and usually originate in the urinary tract (50%), genital system (15%), gastrointestinal system (15%), or the hepatobiliary tract (5%). Ovarian cysts comprise one-third of the masses with a genital origin. Presently described is a case of an ovarian cyst that developed during the antenatal period and transformed into a hemorrhagic cystic mass as a result of torsion. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14744/SEMB.2018.48154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192291PMC
November 2019

What are the Particularities of Gastric and Bariatric Surgery in the Cirrhotic Patient.

Chirurgia (Bucur) 2020 Mar-Apr;115(2):161-168

The objective of this work was to review the entire literature on gastric and bariatric surgery in order to best define the surgical indications and the specifics of their management. A literature review from 1995 to August 2015 was conducted in Pubmed and Google Scholar, using French and English as publication languages. 21 studies were included (level 3 and 4) over 128 identified. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21614/chirurgia.115.2.161DOI Listing

What are the Particularities of Oesophageal Surgery in Cirrhotic Patients.

Chirurgia (Bucur) 2020 Mar-Apr;115(2):155-160

The aim of this paper was to review the entire literature on esophageal surgery to best define the surgical indications and the specifics of their management. The bibliographic research was carried out on Pubmed between January 1995 and June 2015, using French and English as publication languages. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21614/chirurgia.115.2.155DOI Listing

Mucosa-associated lymphoid tissue lymphoma simulating Crohn's disease: A case report.

World J Clin Cases 2020 Apr;8(8):1454-1462

Centre of Hepatology, Gastroenterology and Dietetics, Faculty of Medicine, Vilnius University, Vilnius 03101, Lithuania.

Background: Differential diagnosis between extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue and inflammatory bowel disease is mainly based on histopathologic evaluation of intestinal biopsies, although there is no single definitive diagnostic investigation and that circumstance can lead to misdiagnosis in particular cases. Herein we present a rare, ulcerative form of marginal zone lymphoma which mimics the Crohn's disease (CD) of upper digestive tract.

Case Summary: A 50-year-old man was presented with recurrent episodes of malaise and melena also weight loss. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12998/wjcc.v8.i8.1454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190957PMC

Room Costs for Common Pediatric Hospitalizations and Cost-Reducing Quality Initiatives.

Pediatrics 2020 Jun 4;145(6). Epub 2020 May 4.

Department of Pediatrics, Children's Mercy Kansas City and School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.

Background: Improvement initiatives promote safe and efficient care for hospitalized children. However, these may be associated with limited cost savings. In this article, we sought to understand the potential financial benefit yielded by improvement initiatives by describing the inpatient allocation of costs for common pediatric diagnoses. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1542/peds.2019-2177DOI Listing