122,122 results match your criteria Unilateral Nevoid Telangiectasia


Ruptured Renal Artery Aneurysm in a Pregnant Woman: Case Report and Literature Review.

Rev Bras Ginecol Obstet 2018 Dec 12. Epub 2018 Dec 12.

Universidade Positivo, Curitiba, PR, Brazil.

Renal artery aneurysms (RAAs) are rare and usually asymptomatic; ∼ 90% of them are unilateral. Once diagnosed during pregnancy, they may rupture, presenting a high maternal-fetal risk. The present study reports the case of a 32-year-old pregnant woman with a 30-week gestational age and a ruptured unilateral RAA. Read More

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December 2018

Sh3rf2 Haploinsufficiency Leads to Unilateral Neuronal Development Deficits and Autistic-Like Behaviors in Mice.

Cell Rep 2018 Dec;25(11):2963-2971.e6

State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; Parkinson's Disease Center, Beijing Institute for Brain Disorders, Beijing 100101, China. Electronic address:

Autism spectrum disorders (ASDs) include a variety of developmental brain disorders with clinical findings implicating the dysfunction of the left hemisphere. Here, we generate mice lacking one copy of Sh3rf2, which was detected in ASD patients, to determine whether Sh3rf2 is involved in brain development and whether mutation of SH3RF2 is causative for ASD and the mechanisms linking it to ASD traits. We find that mice with Sh3rf2 haploinsufficiency display significant deficits in social interaction and communication, as well as stereotyped or repetitive behaviors and hyperactivity and seizures. Read More

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December 2018

Education and work participation among adults with congenital unilateral upper limb deficiency in Norway: A cross-sectional study.

PLoS One 2018 12;13(12):e0207846. Epub 2018 Dec 12.

Innlandet Hospital Trust, Department of Physical Medicine and Rehabilitation, Ottestad, Norway.

Objectives: To describe level of education and work participation among adults with congenital unilateral upper limb deficiency (CUULD) in Norway and to explore associations between work participation and demographic and clinical factors.

Methods: Cross-sectional study. In 2012, a postal questionnaire was sent to 186 persons with congenital limb deficiency (CLD), age ≥ 20 years, registered at the TRS National Resource Center for Rare Disorders. Read More

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December 2018

Relationship Between Tinnitus Loudness Measure by Visual Analogue Scale and Psychoacoustic Matching of Tinnitus Loudness.

Otol Neurotol 2019 Jan;40(1):16-21

World Hearing Center, Institute of Physiology and Pathology of Hearing, Warsaw/Kajetany.

Objective: The aim of the study was to assess the relationship between psychoacoustic matches of tinnitus loudness and tinnitus loudness measured with a visual analogue scale (VAS) in patients with normal hearing and patients with hearing loss.

Study Design: Cross-sectional study.

Patients: A clinical group of 140 adult patients (46. Read More

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January 2019

Orthostatic intolerance following hip arthroplasty: Incidence, risk factors and effect on length of stay: a prospective cohort study.

Eur J Anaesthesiol 2018 Dec 11. Epub 2018 Dec 11.

From the Department of Anaesthesiology and Perioperative Medicine, Waitemata District Health Board (MUS, DAR, MTK), Health and Rehabilitation Research Institute, Auckland University of Technology (DAR, PJM), and Faculty of Medical and Health Sciences, University of Auckland (MTK).

Background: Early postoperative mobilisation is important for enhanced recovery, but can be hindered by orthostatic intolerance, characterised by dizziness, nausea, vomiting, feeling of heat, blurred vision and ultimately syncope. Although the incidence of orthostatic intolerance following total hip arthroplasty has been identified, few studies have yet investigated potential risk factors for developing orthostatic intolerance after hip arthroplasty.

Objectives: The aim of this study was to assess the incidence of orthostatic intolerance on the first postoperative day after total hip arthroplasty, potential predisposing risk factors for developing orthostatic intolerance and its effect on length of stay. Read More

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December 2018

Bilateral Congenital Vertical Talus in Association with Beals Contractural Arachnodactyly: A Case Report.

JBJS Case Connect 2018 Dec 12. Epub 2018 Dec 12.

Southland Hospital/University of Otago, Invercargill, New Zealand.

Case: Congenital vertical talus (CVT) is a rare rigid flatfoot disorder with a rocker-bottom flatfoot appearance. It is characterized by hindfoot valgus and equinus, with associated midfoot dorsiflexion and forefoot abduction. We describe a patient who was born with dysmorphic features and subsequently was diagnosed with Beals contractural arachnodactyly. Read More

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December 2018

Comparative biomechanical evaluation of two technologically different microprocessor-controlled prosthetic knee joints in safety-relevant daily-life situations.

Biomed Tech (Berl) 2018 Dec 12. Epub 2018 Dec 12.

Ottobock SE & Co. KGaA, Clinical Research and Services, Research Biomechanics, 37075 Göttingen, Germany.

Safety-relevant gait situations (walking on stairs and slopes, walking backwards, walking with small steps, simulated perturbations of swing phase extension) were investigated in a motion analysis laboratory with six unilateral transfemoral amputees using two different microprocessor-controlled prosthetic knee joints (Rheo Knee XC, C-Leg). A randomized crossover design was chosen. The study results imply that the performance and safety potential of a microprocessor-controlled knee joint can be associated with the individual control algorithms and the technological concepts that are implemented to generate motion resistances for controlling flexion and extension movements. Read More

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December 2018

Variations in lower body stiffness during sports-specific tasks in well-trained female athletes.

Sports Biomech 2018 Dec 12:1-16. Epub 2018 Dec 12.

a School of Exercise Science, Faculty of Health Science , Australian Catholic University , Strathfield , Australia.

The present study aimed to assess the differences in leg stiffness and the associated performance variables between athletes from various training backgrounds during tasks relevant to athletic training. Forty-seven female participants (20 nationally identified netballers, 13 high-level endurance athletes and 14 age-matched controls) completed a sprint, anticipated sidestep change of direction and unilateral repetitive hopping task to assess leg stiffness and the relationship of stiffness between the different tasks. Leg stiffness and performance variables were evaluated with a 10-camera motion analysis system and force plate, and leg stiffness was derived through the McMahon and Cheng methodology (1990). Read More

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December 2018

Paratesticular rhabdomyosarcoma mimicking complicated epididymal cyst.

J Cancer Res Ther 2018 Dec;14(Supplement):S1241-S1243

Department of Urology, Faculty of Medicine, Kemerburgaz University, Medical Park Bursa Hospital, Bursa, Turkey.

Paratesticular rhabdomyosarcoma (RMS) is a rare nongerm cell intrascrotal malignant tumor in children and young adult/teens resulting from the mesenchymal tissues of the tunica vaginalis, epididymis, spermatic cord, and testis. RMS accounts for approximately 7% of all genitourinary tract RMSs and 12% of all pediatric scrotal neoplasms. Patients usually present with a painless unilateral scrotal mass. Read More

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December 2018

Periostin Induces Kidney Fibrosis after Acute Kidney Injury via the p38 MAPK Pathway.

Am J Physiol Renal Physiol 2018 Dec 12. Epub 2018 Dec 12.

Department of Internal Medicine, Seoul National University College of Medicine and Seoul National University Boramae Medical Center, Korea (South), Republic of.

Periostin plays a crucial role in fibrosis, and acute kidney injury results in a high risk of progression to chronic kidney disease. Therefore, we hypothesized that periostin was involved in the progression of acute kidney injury to kidney fibrosis. Unilateral ischemia-reperfusion injury (UIRI) was induced in 7- to 8-week-old male wild-type and periostin- null mice, and the animals were observed for 6 weeks. Read More

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December 2018

Evaluation of dual pathology among drug-resistant epileptic patients with hippocampal sclerosis.

Neurol Sci 2018 Dec 11. Epub 2018 Dec 11.

Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Purpose: Dual pathology (DP) is defined as simultaneous presence of hippocampal sclerosis (HS) and any other pathology in the brain. Since this is a less probed concept, we aimed to evaluate the frequency and characteristics of DP among drug-resistant epileptic patients with HS.

Methods: This is a cross-sectional study conducted during 2007-2016 in Kashani Comprehensive Epilepsy Center, Isfahan, Iran. Read More

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December 2018

Novel unilateral C1 double screw and ipsilateral C2 pedicle screw placement combined with contralateral laminar screw-rod fixation for atlantoaxial instability.

Eur Spine J 2018 Dec 11. Epub 2018 Dec 11.

Department of Orthopedics, The Second Affiliated Hospital of Chongqing Medical University, No. 76 Linjiang Road, Yuzhong District, Chongqing, 400010, People's Republic of China.

Purpose: To investigate the anatomical and biomechanical feasibility of the unilateral C1 double screw [pedicle screw (PS) + lateral mass screw (LMS)] and ipsilateral C2 PS combined with contralateral C2 laminar screw (LS)-rod fixation for atlantoaxial instability by comparison with traditional posterior fixation methods.

Methods: Fifteen sets of complete dry bony specimens of atlas were used for morphometric analysis. The working length, width and thickness of the C1 PSs and LMSs were manually measured. Read More

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December 2018

Unilateral Conditioning Contractions Enhance Power Output in Elite Short Track Speed Skaters.

Sports Med Int Open 2018 Nov 15;2(6):E185-E190. Epub 2018 Nov 15.

École de kinésiologie et des sciences de l'activité physique, Université de Montréal, Montréal, Canada.

The objective of the present study was to assess the effect of unilateral lower-body-conditioning muscle contractions during multiple sets of fatiguing repeated jumps in elite athletes. Five elite short-track speed-skating athletes performed 9 sets of 6 maximal consecutive jumps on 2 separate occasions: with (COND) and without (CTRL) preliminary voluntary conditioning contractions (CC) 5 min before the beginning of the sets. The CC consisted of 2 consecutive 3 s maximal unilateral isometric squats against a fixed bar, resulting in a 6 s overall isometric contraction per leg. Read More

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November 2018

Orbital compartment syndrome resulting in unilateral blindness in two dogs.

Open Vet J 2018 22;8(4):445-451. Epub 2018 Nov 22.

Department of Clinical Sciences, Companion and Equine Animals, Ophthalmology, University of Liège, Quartier Vallée 2, Avenue de Cureghem 3, 4000 Liège, Belgium.

Orbital compartment syndrome (OCS) is described in humans as an acute rise in intraorbital pressure following a severe and rapidly evolving orbital affection. It includes orbital oedema, haemorrhage or infection causing a marked reduction in local blood perfusion, and severely affecting the orbital neurovascular structures. If not promptly recognised and treated, it results in irreversible blindness. Read More

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November 2018

Osgood-Schlatter Disease Unveiled Under High-frequency Ultrasonogram.

Authors:
Md Abu B Siddiq

Cureus 2018 Oct 4;10(10):e3411. Epub 2018 Oct 4.

Physical Medicine and Rheumatology, Brahmanbaria Medical College, Brahmanbaria, BGD.

Osgood-Schlatter disease is a painful condition, affecting the tibial tuberosity of physically active children with a painful bump that aggravates with repetitive impacts over the affected area during exercise, sports, or even usual daily activities. The condition is usually unilateral; however, bilateral presentation is not unlikely. In addition to clinical features, a unique radiological finding appears worthy in terms of accurate diagnosis. Read More

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October 2018

Time Course of Upper Limb Function in Children with Unilateral Cerebral Palsy: A Five-Year Follow-Up Study.

Neural Plast 2018 14;2018:2831342. Epub 2018 Nov 14.

KU Leuven, University of Leuven, Department of Rehabilitation Sciences, Leuven, Belgium.

Knowledge on long-term evolution of upper limb function in children with unilateral cerebral palsy (CP) is scarce. The objective was to report the five-year evolution in upper limb function and identify factors influencing time trends. Eighty-one children (mean age 9 y and 11 mo, SD 3 y and 3 mo) were assessed at baseline with follow-up after 6 months, 1, and 5 years. Read More

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November 2018

Functional and Structural Brain Plasticity in Adult Onset Single-Sided Deafness.

Front Hum Neurosci 2018 27;12:474. Epub 2018 Nov 27.

Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, CA, United States.

Single-sided deafness (SSD) or profound unilateral hearing loss obligates the only serviceable ear to capture all acoustic information. This loss of binaural function taxes cognitive resources for accurate listening performance, especially under adverse environments or challenging tasks. We hypothesized that adults with SSD would manifest both functional and structural brain plasticity compared to controls with normal binaural hearing. Read More

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November 2018

Association between seizure freedom and default mode network reorganization in patients with unilateral temporal lobe epilepsy.

Epilepsy Behav 2018 Dec 8. Epub 2018 Dec 8.

Epilepsy Center, Medical Center - Faculty of Medicine, University of Freiburg, Germany; Faculty of Medicine, University of Freiburg, Germany; Freiburg Brain Imaging Center, Medical Center - Faculty of Medicine, University of Freiburg, Germany.

Rationale: The spontaneous synchronized activity and intrinsic organization of the Default Mode Network (DMN) has been found to be altered because of epileptic activity of temporal lobe origin. Thus, the aim of the present study was to compare DMN's topological properties in patients with seizure-free (SF) and not seizure-free (NSF) temporal lobe epilepsy (TLE).

Methods: Functional connectivity within the DMN was determined from an 8-minute resting state functional magnetic resonance imaging (fMRI) in 27 patients with TLE (12 SF, 15 NSF) and 15 healthy controls (HC). Read More

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December 2018
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Cold effect in median nerve conductions in clinical carpal tunnel syndrome with normal nerve conduction studies.

J Clin Neurosci 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurology, Kirikkale University, Faculty of Medicine, Yenişehir Mahallesi, Ankara Road 7.Km., Kırıkkale Üniversitesi Kampüsü, 71450 Yahşihan, Kırıkkale, Turkey. Electronic address:

Clinical diagnosis of carpal tunnel syndrome (CTS) is confirmed by nerve conduction studies (NCS). In some cases, NCS may be normal. We aimed to demonstrate changes of distal motor latency (DML) and nerve conduction velocity (NCV) pathology of demyelination in entrapment neuropathy with cold application in case of clinical CTS with normal NCS. Read More

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December 2018
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A three-dimensional scapular motion analysis in patients with arthroscopic anterior capsulolabral repair of the shoulder: The effect of scapular stabilization taping.

J Orthop Sci 2018 Dec 8. Epub 2018 Dec 8.

Hacettepe University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Ankara, Turkey.

Background: The aim of this study was to investigate the scapular kinematics during dynamic humeral movements in patients with arthroscopic anterior capsulolabral repair of the shoulder along with the potential biomechanical corrective effects of scapular stabilization taping.

Methods: Twenty patients with unilateral traumatic anterior shoulder instability and arthroscopic anterior capsulolabral repair participated in the study. Dynamic shoulder kinematics were assessed during the scapular plane shoulder elevation for both the operated and non operated shoulders and also under two conditions: no-taping and taping. Read More

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December 2018

Successful arterial switch operation for transposition of the great arteries with intact ventricular septum and congenital diaphragmatic hernia: A case report.

J Cardiol Cases 2014 Jul 17;10(1):39-41. Epub 2014 May 17.

Department of Cardiology, Aichi Children's Health and Medical Center, Obu, Japan.

We report performing a successful arterial switch operation on a full-term male infant with transposition of the great arteries and intact ventricular septum associated with a congenital diaphragmatic hernia. The patient developed severe persistent pulmonary hypertension after successful repair of a left congenital diaphragmatic hernia that restricted pulmonary blood flow into the hypoplastic left lung, and subsequent unilateral pulmonary congestion of the unaffected right lung occurred because of the hemodynamics generated by the transposition of the great arteries. Intravenous epoprostenol with nitric oxide inhalation and mechanical hypoventilation effectively controlled pulmonary vascular resistance before the arterial switch operation was performed. Read More

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In vivo cell type-specific CRISPR knockdown of dopamine beta hydroxylase reduces locus coeruleus evoked wakefulness.

Nat Commun 2018 12 6;9(1):5211. Epub 2018 Dec 6.

Department of Psychiatry and Behavioral Sciences, Stanford University, 1201 Welch Road, Stanford, CA, 94305, USA.

Locus coeruleus (LC) neurons in the brainstem have long been associated with attention and arousal. Optogenetic stimulation of LC-NE neurons induces immediate sleep-to-wake transitions. However, LC neurons also secrete other neurotransmitters in addition to NE. Read More

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December 2018

The Value of Unilateral CIs, CI-CROS and Bilateral CIs, with and without Beamformer Microphones, for Speech Understanding in a Simulation of a Restaurant Environment.

Audiol Neurootol 2018 Dec 11;23(5):270-276. Epub 2018 Dec 11.

Advanced Bionics, Valencia, California, USA.

Objective: Our primary aim was to determine, in a simulation of a crowded restaurant, the value to speech understanding of (i) a unilateral cochlear implant (CI), (ii) a CI plus CROS (contralateral routing of signals) aid system and (iii) bilateral CIs when tested with and without beamforming microphones.

Design: The listeners were 7 CI listeners who had used bilateral CIs for an average of 9 years. The listeners were tested with three device configurations (bilateral CI, unilateral CI + CROS, and unilateral CI), two signal processing conditions (without and with beamformers) and with speech either from +90°, -90°, or from the front. Read More

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December 2018

The association between Parkinson's disease symptom side-of-onset and performance on the MDS-UPDRS scale part IV: Motor complications.

J Neurol Sci 2018 Dec 4;396:262-265. Epub 2018 Dec 4.

Division of General Medicine and Geriatrics, Department of Medicine, Emory School of Medicine, 1648 Pierce Dr. NE, Atlanta, GA 30307, USA; Atlanta VA Center for Visual and Neurocognitive Rehabilitation, 1670 Clairmont Rd., Decatur, GA 30033, USA; Department of Rehabilitation Medicine, Emory School of Medicine, 1648 Pierce Dr. NE, Atlanta, GA 30307, USA. Electronic address:

Introduction: Parkinson's disease (PD) is a neurodegenerative condition associated with aging characterized by loss of dopamine-producing neurons in the substantia nigra pars compacta and a reduction in dopamine levels in the striatum. PD is commonly treated using dopamine-replacement medication called levodopa. Levodopa has decreasing efficacy over time. Read More

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December 2018

Postoperative antiplatelet therapy in the treatment of complex basilar apex aneurysms implementing Hunterian ligation and extracranial-to-intracranial bypass: review of the literature with an illustrative case report.

World Neurosurg 2018 Dec 8. Epub 2018 Dec 8.

Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

Large, broad-based basilar artery (BA) apex aneurysms involving multiple arterial origins are complex lesions commonly not amenable to direct clipping or endovascular management. BA proximal (Hunterian) occlusion with extracranial-to-intracranial bypass is a supported strategy if one or both posterior communicating arteries are small. Hunterian ligation risks sudden aneurysm thrombosis and thromboembolism in the perforator rich BA apex. Read More

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December 2018

Bilateral projections to the thalamus from individual neurons in the inferior colliculus.

J Comp Neurol 2018 Dec 11. Epub 2018 Dec 11.

Department of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio, USA.

The medial geniculate body (MG) receives a large input from the ipsilateral inferior colliculus (IC) and a smaller but substantial input from the contralateral IC. Both crossed and uncrossed inputs comprise a large percentage of glutamatergic cells and a smaller percentage of GABAergic cells. We used double labeling with fluorescent retrograde tracers to identify individual IC cells that project bilaterally to the MGs in adult guinea pigs. Read More

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December 2018
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Oncologic outcomes in patients with 1-cm to 4-cm differentiated thyroid carcinoma according to extent of thyroidectomy.

Head Neck 2018 Dec 10. Epub 2018 Dec 10.

Department of Surgery, Thyroid Cancer Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: Recent guidelines advocate unilateral thyroidectomy for low-risk 1-cm to 4-cm differentiated thyroid cancer (DTC). This study was designed to examine the association between the extent of thyroidectomy and oncologic outcomes in patients with 1-cm to 4-cm DTC.

Materials And Methods: From April 1978 to December 2011, 16 057 patients with DTC underwent thyroidectomy at Yonsei University Hospital. Read More

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December 2018

HGF alleviates renal interstitial fibrosis via inhibiting the TGF-β1/SMAD pathway.

Eur Rev Med Pharmacol Sci 2018 Nov;22(22):7621-7627

Department of Nephrology, Yancheng TCM Hospital Affiliated to Nanjing University of Chinese Medicine, Yancheng, China.

Objective: To study the role of HGF (stem cell growth factor) in renal interstitial fibrosis and to explore its underlying mechanism.

Materials And Methods: A unilateral ureteral obstruction (UUO) mouse model was first constructed, and kidney samples of mice were then collected. Fibrosis-related indicators in UUO mice kidney were detected by Western blot. Read More

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November 2018
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[Management of vestibular schwannomas].

Laryngorhinootologie 2018 Dec 10;97(12):875-896. Epub 2018 Dec 10.

Vestibular schwannomas are benign neoplasms originating from the Schwann cells of the vestibular vestibular nerve of the vestibulocochlear nerve, and rarely from the pars cochlearis. These are tumors that are in contact with the nerve but do not bind the fibers. Benign neoplasms of the Schwann cells of the auditory and equilibrium nerves can also occur primarily in the inner ear and are referred to as intralabyrinthine schwannomas (ILS). Read More

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December 2018
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The miRNA-184 drives renal fibrosis by targeting HIF1AN in vitro and in vivo.

Authors:
Bin Chen

Int Urol Nephrol 2018 Dec 10. Epub 2018 Dec 10.

Kidney Department, Zhenhai People's Hospital of Ningbo City (Ningbo No.7 Hospital), 718 Nanerxi Road, Luotuo Subdistrict, Zhenhai, Ningbo, People's Republic of China.

Progressive renal fibrosis is the last phase of chronic kidney disease and results in renal failure. Micro-RNA has been demonstrated as important agent to drive organ fibrosis. However, the precise mechanisms are not fully understood. Read More

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December 2018

Robotic-assisted versus laparoscopic unilateral inguinal hernia repair: a comprehensive cost analysis.

Surg Endosc 2018 Dec 7. Epub 2018 Dec 7.

Washington University School of Medicine, Box 8109, St. Louis, MO, 63110, USA.

Background: Cost-effectiveness of robotic-assisted surgery is still debatable. Robotic-assisted inguinal hernia repair has no clear clinical benefit over laparoscopic repair. We performed a comprehensive cost-analysis comparison between the two approaches for evaluation of their cost-effectiveness in a large healthcare system in the Western United States. Read More

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December 2018
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Minimally invasive internal fixator for unstable pelvic ring injuries with a pedicle screw-rod system: a retrospective study of 23 patients after 13.5 months.

Arch Orthop Trauma Surg 2018 Dec 8. Epub 2018 Dec 8.

Department of Orthopaedic Surgery, Physical Medicine and Rehabilitation, University of Munich (LMU), Munich, Germany.

Purpose: Pelvic ring fractures are challenging injuries and require effective treatment due to the frequently compromised patient condition. The aim of this study was to evaluate the outcome of unstable pelvic ring injuries treated with a minimally invasive pedicle screw-rod system.

Methods: Retrospective analysis was performed for patients with an unstable pelvic ring injury that were treated with a minimally invasive anterior internal pelvic fixator (INFIX) with or without a posterior pedicle screw-rod fixator (6/2012-4/2015). Read More

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December 2018

Age-associated hippocampal volume changes in childhood arterial ischemic stroke.

Childs Nerv Syst 2018 Dec 8. Epub 2018 Dec 8.

Department of Radiology, Children's Hospital Colorado, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA.

Purpose: Recent evidence suggests that recovery from secondary neurodegeneration following arterial ischemic stroke (AIS) may be related to age at injury and site of occlusion. We conducted a study of hippocampal volume (HCV) in a cohort of pediatric patients with middle cerebral artery (MCA) territory AIS to determine whether HCV would be preserved in younger children as compared to older children.

Methods: This single-center, HIPAA-compliant retrospective study was approved by the institutional review board. Read More

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December 2018

A novel seizure quality index based on ictal parameters for optimizing clinical decision-making in electroconvulsive therapy. Part 2: Validation.

Eur Arch Psychiatry Clin Neurosci 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health, Heidelberg University, J5, 68159, Mannheim, Germany.

Early identification of patients who are at a high risk for an unfavorable outcome to ECT during the treatment course might be beneficial because it provides an opportunity for timely intensification or optimization of stimulus conditions. We aimed to validate a previously developed seizure quality index (SQI) that delivers a clinically relevant outcome prediction early in the treatment course and can be used within common clinical setting. Therefore, a prospective study was conducted. Read More

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December 2018
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The clinical and imaging features of gray matter heterotopia: a clinical analysis on 15 patients.

Neurol Sci 2018 Dec 10. Epub 2018 Dec 10.

Department of Neurology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, China.

Objective: To investigate the clinical and imaging features of gray matter heterotopia (GMH) and improve the clinicians' understanding of the disease.

Methods: A retrospective study was performed on 15 patients with GMH diagnosed at The Affiliated Hospital of Xuzhou Medical University from November 2014 to November 2016. Their clinical and imaging features are also summarized. Read More

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December 2018

A non-invasive biomarker of type III collagen degradation reflects ischaemia reperfusion injury in rats.

Nephrol Dial Transplant 2018 Dec 7. Epub 2018 Dec 7.

Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.

Background: Maintenance of kidney function in kidney allografts remains a challenge, as the allograft often progressively develops fibrosis after kidney transplantation. Fibrosis is caused by the accumulation of extracellular matrix proteins like type I and III collagen (COL I and III) that replace the functional tissue. We assessed the concentrations of a neo-epitope fragment of COL III generated by matrix metalloproteinase-9 cleavage (C3M) in two rat models resembling the ischaemic injury taking place following kidney transplantation. Read More

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December 2018

Cerebrolysin increases motor recovery and decreases inflammation in a mouse model of autoimmune encephalitis.

Rom J Morphol Embryol 2018 ;59(3):755-762

Department of Research Methodology, University of Medicine and Pharmacy of Craiova, Romania;

Multiple sclerosis (MS) is a complex chronic neurodegenerative disease that involves an abnormal autoimmune response directed against the brain, nerves and spinal cord; it is considered the most frequent cause of neurological disability, because MS-associated inflammatory lesions can affect a wide range of systems to a varying degree and may cause a plethora of neurological comorbidities and symptoms. The symptoms are quite variable from patient to patient and depend on the spatial distribution of the central nervous system (CNS) lesions, but usually involve sensory disturbances, cognitive deficits, unilateral vision loss, bladder dysfunction, ataxia, fatigue, double vision, weakness of the limbs and intestinal disorders. Experimental autoimmune encephalitis (EAE) mouse model reproduces the pathological features of the human disease, and is a widely used model used for studying the pathology and different treatment options in the preclinical stage. Read More

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January 2018

Unilateral Chronic Lung Allograft Dysfunction Assessed by Biphasic Computed Tomographic Volumetry in Bilateral Living-donor Lobar Lung Transplantation.

Transplant Direct 2018 Nov 12;4(11):e398. Epub 2018 Oct 12.

Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Background: Early diagnosis of unilateral chronic lung allograft dysfunction (CLAD) is difficult because the unaffected contralateral lung functions as a reservoir in bilateral living-donor lobar lung transplantation (LDLLT). We previously reported the usefulness of Xe ventilation scintigraphy for detection of unilateral change, but the supply of Xe has been stopped globally. The present study aimed to examine the usefulness of inspiratory and expiratory computed tomography (I/E CT) volumetry for detection of unilateral change in CLAD patients. Read More

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November 2018

Facial Soft-tissue Mobility: Baseline Dynamics of Patients with Unilateral Facial Paralysis.

Plast Reconstr Surg Glob Open 2018 Oct 4;6(10):e1955. Epub 2018 Oct 4.

Department of Orthodontics, Tufts University School of Dental Medicine, Boston, Mass.

Background: The aims of this observational study were 2-fold: (1) To demonstrate a method and measures to quantify impaired facial soft-tissue movements in patients with facial paralysis; and (2) To quantify the differences in magnitude and velocity of facial soft-tissue movements between patients with facial paralysis and control participants.

Methods: The study sample that addressed both aims consisted of 20 adults with acute, unilateral, flaccid facial paralysis who presented at the onset of their paralysis, and a control group of 20 healthy adults. Dynamic 3D facial movement data were collected from each participant during 11 facial animations. Read More

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October 2018

Prepectoral Hammock and Direct-to-implant Breast Reconstruction in 10 Minutes: A Focus on Technique.

Plast Reconstr Surg Glob Open 2018 Oct 2;6(10):e1931. Epub 2018 Oct 2.

Odense University Hospital and Lillebaelt Hospital, Vejle, Denmark.

Background: Breast animation deformity has sparked a reappraisal of the prepectoral implant placement in breast reconstruction. Our approach for direct-to-implant breast reconstruction (DIR) has evolved from a dual plane muscle/mesh coverage to a simple prepectoral hammock covering just the inferolateral part of the implant without the muscle. The aim of this study was to test the procedure in a prospective case series with emphasis on reconstructive outcome. Read More

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October 2018

Muscular imbalances and balance capability in dance.

J Occup Med Toxicol 2018 3;13:36. Epub 2018 Dec 3.

2Department Sports Medicine and Training Science, Christian-Albrechts-Universität Kiel, Institute of Sports Science, Olshausenstrasse 74, 24098 Kiel, Germany.

Objective: A high unilateral load to the musculoskeletal system is specific for formation dance. Due to the lack of data the aim of this study was the side-related (right - left) analysis of strength- and balance capability subject to injuries, gender and performance standards.

Methods:  = 51 dancers (m:  = 24, f: m = 27) of two performance levels participated in this cross-sectional study. Read More

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December 2018

Cytology of the fallopian tube: A screening model for high-grade serous carcinoma.

Cytojournal 2018 12;15:28. Epub 2018 Nov 12.

Address: Department of Medical and Surgical Gynecology, Mayo Clinic, Jacksonville, FL, USA.

Ovarian cancer is a heterogeneous disease having the highest gynecologic fatality in the United States with a 5-year survival rate of 46.5%. Poor overall prognosis is mostly attributed to inadequate screening tools, and the majority of diagnoses occur at late stages of the disease. Read More

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November 2018
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Dataset of output impedances of current sources by analytical method and by experimental method.

Data Brief 2018 Dec 15;21:2063-2074. Epub 2018 Nov 15.

National Institute of Technology, Ashok Rajpath, Patna 800005, Bihar, India.

The dataset provided in this article are related to the research article entitled "The Journey of Universal Hybrid-pi model-from its Inception to Experimental Validation and its impact on Analog Circuit Design" (Sharma, in press). While analyzing dataset of the incremental output impedances of the BJT Current Sources, Conventional Hybrid-pi model, and Unilateral Model grossly underestimate the output impedances whereas Universal Hybrid-pi Model gives a much larger range of output impedances from ro to 40ro. The quest for these enhanced prediction led to the discovery of "Variable Latching Effect" (Sharma, 1990). Read More

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December 2018

MMP-9 inhibitors impair learning in spontaneously hypertensive rats.

PLoS One 2018 11;13(12):e0208357. Epub 2018 Dec 11.

Department of Neurology, University of New Mexico, Albuquerque, New Mexico, United States of America.

Vascular cognitive impairment dementia (VCID) is a major cause of cognitive loss in the elderly. Matrix metalloproteinases (MMPs) are a family of proteases involved in remodeling the extracellular matrix in development, injury and repair. Blood-brain barrier (BBB) disruption due to inflammation mediated by MMPs is a mechanism of white matter injury. Read More

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December 2018

A comparison of surgical outcomes between pre-and full-term patients with exotropia.

PLoS One 2018 7;13(12):e0208848. Epub 2018 Dec 7.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea.

Purpose: To compare the surgical outcomes between pre- and full-term patients with exotropia and to examine the factors associated with surgical outcomes.

Methods: This retrospective study included 48 pre- and 432 full-term patients with basic-type exotropia who underwent unilateral or bilateral lateral rectus muscle (ULR or BLR) recession. Preoperative characteristics and surgical outcomes were compared between the pre- and full-term infants. Read More

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December 2018

Otopathology of Unilateral Cochlear Implantation in Patients With Bilateral Temporal Bone Fracture.

Otol Neurotol 2019 Jan;40(1):e14-e19

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary.

Objective: Audiometric outcomes following cochlear implantation (CI) in patients with temporal bone fracture (TBF) are variable and the pathophysiology is not well understood. Herein, we describe otopathologic findings in two such cases to provide insight into pathophysiology and outcomes.

Patients: Two patients had a history of head trauma resulting in bilateral TBF and sudden, profound, sensorineural hearing loss. Read More

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January 2019

Outcome of Patients with Complete Unilateral Cleft Lip and Palate: 20-Years Follow-up of Treatment Protocol.

Plast Reconstr Surg 2018 Nov 26. Epub 2018 Nov 26.

Plastic & Reconstructive Surgery, and Craniofacial Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan. Email:

Background: The treatment plan for cleft lip and palate varies among centers, and requires long-term evaluation of its final outcome.

Methods: A consecutive patients born in 1994 to 1996 were reviewed. Inclusion criteria were complete unilateral cleft lip and palate, receiving all treatment procedures in the team and continuous follow-ups until 20 years of age. Read More

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November 2018

FLUORESCEIN ANGIOGRAPHY FINDINGS IN UNILATERAL PERSISTENT FETAL VASCULATURE.

Retina 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, Chang-Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.

Objective: This study aims to examine retinal vascular findings for affected eyes and contralateral eyes as well in typical cases of unilateral persistent fetal vasculature.

Methods: We retrospectively reviewed all patients evaluated at Chang Gung Memorial Hospital, Linkou, for unilateral persistent fetal vasculature between January 2008 and July 2017. All patients underwent fluorescein angiography (FA) examination under general anesthesia. Read More

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November 2018

Rapid Amelioration of Clozapine-Resistant Thought Broadcast in Schizophrenia With High-Dose Right Unilateral Ultrabrief Electroconvulsive therapy-A Single Case Report.

J ECT 2018 Dec 7. Epub 2018 Dec 7.

Mood Disorders UnitCumberland Hospital Riverview and Department of Psychiatry Westmead Clinical School University of Sydney Westmead, New South Wales Australia Department of PsychiatryWestmead Clinical SchoolUniversity of SydneyWestmead, New South WalesAustralia.

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December 2018

OPTIC DISK ASTROCYTOMA UNASSOCIATED WITH TUBEROUS SCLEROSIS COMPLEX MANAGED WITH SURGICAL EXCISION AND A 7-YEAR FOLLOW-UP.

Authors:
Yao Lu Yimin Xu

Retin Cases Brief Rep 2018 Nov 28. Epub 2018 Nov 28.

Department of Ophthalmology, Ministry of Education, Key Laboratory of Vision Loss and Restoration, Peking University Third Hospital, Beijing, China.

Purpose: Optic disk astrocytoma is a rare variant of congenital hamartoma, which is usually associated with tuberous sclerosis complex. Generally, it is stationary but in rare cases, it can show progressive growth and cause severe local complications.

Methods: Clinical-pathologic correlation. Read More

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November 2018