Exp Eye Res 2021 03 23;204:108450. Epub 2021 Jan 23.
Open FIESTA Center, International Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China; Biomanufacturing Engineering Laboratory, International Graduate School at Shenzhen, Tsinghua University, Shenzhen, 518055, PR China; Department of Mechanical Engineering, Biomanufacturing Center, Tsinghua University, Beijing, PR China. Electronic address:
Purpose: This study examined the patterned treatment of corneal collagen cross-linking (CXL) for keratoconus to reduce the complications caused by ultraviolet (UV) irradiation. By modifying the method of UV irradiation during the cross-linking process, cross-linking with a special structure is achieved, and the cross-linking effect is analyzed and compared to that of traditional cross-linking. By constructing an animal model of keratoconus, the process and effect of corneal cross-linking can be investigated more fundamentally. Read More