168,665 results match your criteria Ultraviolet Keratitis


Preparation of pH-responsive avermectin/feather keratin-hyaluronic acid with anti-UV and sustained-release properties.

Colloids Surf B Biointerfaces 2018 Dec 6;175:291-299. Epub 2018 Dec 6.

School of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou, PR China. Electronic address:

In an effort to improve the utilization of pesticides, an environmentally friendly carrier material was prepared to encapsulate pesticides and to prevent pesticides from decomposing under natural conditions with sustained-release effect. The carrier of feather keratin-hyaluronic acid (FK-HA) was prepared by Maillard reaction. Using avermectin (AVM) as a model drug, AVM/FK-HA was obtained by heating. Read More

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December 2018

Synthesis and Properties of Magnetic Aryl-Imidazolium Ionic Liquids with Dual Brønsted/Lewis Acidity.

Materials (Basel) 2018 Dec 13;11(12). Epub 2018 Dec 13.

Department of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin 64002, Taiwan.

A series of unique tunable aryl-imidazolium magnetic ionic liquids (MILs) with dual acidity that contain both Brønsted and Lewis acidic sites (abbreviated as B-L MILs) were synthesized and characterized using nuclear magnetic resonance and mass spectrometry. Physical properties, such as thermal properties, magnetic susceptibility, and Brønsted and Lewis acidity, were measured. These properties were found to depend on the cation structure. Read More

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December 2018

Basic chemical peeling-superficial and medium-depth peels.

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Chemical peeling, or chemexfoliation, has been used for centuries to improve signs of ultraviolet light-induced sun damage. Over the last 30 years, the science behind chemical peeling has evolved, increasing our understanding of the role of peeling ingredients and treatment indications. The depth of peels is directly related to improved results and to the number of complications that can occur. Read More

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December 2018
2 Reads

Ultrahigh-Sensitive Broadband Photodetectors Based on Dielectric Shielded MoTe /Graphene/SnS p-g-n Junctions.

Adv Mater 2018 Dec 14:e1805656. Epub 2018 Dec 14.

Department of Physics, Southern University of Science and Technology, Shenzhen, 518055, China.

2D atomic sheets of transition metal dichalcogenides (TMDs) have a tremendous potential for next-generation optoelectronics since they can be stacked layer-by-layer to form van der Waals (vdW) heterostructures. This allows not only bypassing difficulties in heteroepitaxy of lattice-mismatched semiconductors of desired functionalities but also providing a scheme to design new optoelectronics that can surpass the fundamental limitations on their conventional semiconductor counterparts. Herein, a novel 2D h-BN/p-MoTe /graphene/n-SnS /h-BN p-g-n junction, fabricated by a layer-by-layer dry transfer, demonstrates high-sensitivity, broadband photodetection at room temperature. Read More

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December 2018

Visible light accelerates the ultraviolet A-induced degradation of eumelanin and pheomelanin.

Pigment Cell Melanoma Res 2018 Nov 22. Epub 2018 Nov 22.

Department of Chemistry, Fujita Health University School of Health Sciences, Toyoake, Japan.

Exposure to excess ultraviolet (UV) A radiation induces the degradation/modification of both eumelanin and pheomelanin that may be deleterious to pigmented tissues. Although the spectral distribution of solar energy comprises nearly half of visible light (VL), few studies have been conducted to examine the role of VL in the photodegradation of both types of melanin, either VL alone or in combination with UVA. In this study, we examined the effects of physiological doses of VL (150 to 300 J cm ) alone or in combination with a physiological dose of UVA (20 J cm ) in normal human epidermal melanocytes. Read More

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November 2018

Interaction of body mass index or waist-to-hip ratio and sun exposure associated with nonmelanoma skin cancer: A prospective study from the Women's Health Initiative.

Cancer 2018 Dec 11. Epub 2018 Dec 11.

Division of Dermatology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.

Background: The incidence of nonmelanoma skin cancer (NMSC) exceeds the incidence of all other types of cancers combined. Cumulative sun exposure and intermittent sun exposure are known risk factors for the development of NMSC. Because obesity has been shown to decrease the risk of NMSC incidence, this study investigated whether the risk of NMSC with sun exposure was consistent across different levels of body size. Read More

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December 2018

Organic Pollutant Degradation in Water by VUV/UV/H2O2 Process: Inhibition and Enhancement Roles of H2O2.

Environ Sci Technol 2018 Dec 14. Epub 2018 Dec 14.

A vacuum-ultraviolet/ultraviolet (VUV/UV) mercury lamp was found to be a highly efficient radiation source for UV-based advanced oxidation processes (AOPs). If this lamp could enhance the UV/H2O2 process, it would be very attractive. Hence, we have investigated sulfamethazine (SMN) degradation by the VUV/UV/H2O2 process based on a bench-scale mini-fluidic VUV/UV photoreaction system (MVPS), a pilot reactor, and a model analysis. Read More

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December 2018

Structure, Molecular Modification, and Anti-radiation Activity of Melanin from Lachnum YM156 on Ultraviolet B-Induced Injury in Mice.

Appl Biochem Biotechnol 2018 Dec 14. Epub 2018 Dec 14.

School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.

The purpose of this study was to examine the protective effects of intracellular homogeneous melanin produced by Lachnum YM156 (LIM) against ultraviolet B (UVB) induced damage in mice. The possible structural formula of the LIM was concluded based on elemental analysis, ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR), and mass spectrometry (MS). The LIM was modified by arginine to improve its water solubility and biological activities. Read More

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December 2018

Quantum dot-based fluorescent probes for targeted imaging of the EJ human bladder urothelial cancer cell line.

Exp Ther Med 2018 Dec 28;16(6):4779-4783. Epub 2018 Sep 28.

Department of Urology, Robert Debré Teaching Hospital, University of Reims, 51100 Reims, France.

QDs are a type of inorganic nanoparticle with unique optical properties. As a fluorescent label, QDs are widely used in biomedical fields. In the present study, fluorescent probes of quantum dots (QDs) conjugated with a prostate stem cell antigen (PSCA) monoclonal antibody (QD-PSCA) were prepared to study the targeted imaging of QD-PSCA probes in EJ human bladder urothelial cancer cells and analyze the feasibility of QD-based non-invasive tumor-targeted imaging . Read More

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December 2018

Corrigendum: UV-B Pre-treatment Alters Phenolics Response to Infection in a Structure-Dependent Way in Peach Skin.

Front Plant Sci 2018 29;9:1747. Epub 2018 Nov 29.

Department of Agriculture, Food and Environment, University of Pisa, Pisa, Italy.

[This corrects the article DOI: 10.3389/fpls.2018. Read More

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November 2018

Evaluation of remineralization potential and mechanical properties of pit and fissure sealants fortified with nano-hydroxyapatite and nano-amorphous calcium phosphate fillers: An study.

J Conserv Dent 2018 Nov-Dec;21(6):681-690

Department of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Objectives: The aim of this study was: (i) to formulate pit and fissure sealants (PFS) containing nano-hydroxyapatite (nHAP) filler; nHAP filler and silica co-filler; nHAP and nano-Amorphous Calcium Phosphate (nACP) co-filler, (ii) to evaluate physical properties; degree of conversion (DOC), curing depth (CD) and mechanical properties; microshear bond strength (MBS) of fortified PFS, and (iii) to assess remineralization potential and release of Ca and PO ions from newly synthesized sealants.

Materials And Methods: Four PFS were prepared using monomers with mixture of 35.5 wt % BisGMA, 35. Read More

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December 2018

The globular cluster-dark matter halo connection.

Mon Not R Astron Soc 2017 Dec 24;472(3):3120-3130. Epub 2017 Aug 24.

Department of Astronomy, The University of Texas at Austin, 2515 Speedway, Stop C1400, Austin, TX 78712-1205, USA.

I present a simple phenomenological model for the observed linear scaling of the stellar mass in old globular clusters (GCs) with = 0 halo mass in which the stellar mass in GCs scales linearly with halo mass at = 6 above a minimum halo mass for GC formation. This model reproduces the observed - relation at = 0 and results in a prediction for the minimum halo mass at = 6 required for hosting one GC: ( = 6) = 1.07 × 10 M. Read More

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December 2017

In vitro removal of anti-infective agents by a novel cytokine adsorbent system.

Int J Artif Organs 2018 Dec 13:391398818812601. Epub 2018 Dec 13.

1 Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Objectives:: The aim of this study is to describe the in vitro adsorption of anti-infective drugs onto an extracorporeal cytokine adsorber.

Methods:: Various anti-infective drugs (β-lactams, quinolones, aminoglycosides, glycopeptides, azole antimycotics) were prepared in normal saline 0.9% and human albumin 5%, and pumped through a cytokine cartridge (CytoSorb; CytoSorbents Corporation, Monmouth Junction, NJ, USA) at a flow rate of 1. Read More

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December 2018

Identification of lipids of the stratum corneum by high performance thin layer chromatography and mass spectrometry.

Eur J Mass Spectrom (Chichester) 2018 Dec 13:1469066718815380. Epub 2018 Dec 13.

3 Pierre Fabre Dermo-cosmétique, Pharmacology Unit, Toulouse, France.

The stratum corneum, the outermost layer of the epidermis, is the most important skin barrier against exogenous physical and chemical effects, in addition to protecting against dehydration. Ceramides are integral parts of the intercellular lipid lamellae of the stratum corneum and play an important role in the barrier function of mammalian skin. Ceramides are sphingolipids consisting of sphingoid bases linked to fatty acids by an amide bond. Read More

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December 2018

The Effect of Gamma and Beta Radiation on a UVTRON Flame Sensor: Assessment of the Impact on Implementation in a Mixed Radiation Field.

Sensors (Basel) 2018 Dec 12;18(12). Epub 2018 Dec 12.

Characterisation, Inspection & Decontamination Group, Sellafield Ltd., Cumbria CA20 1PG, UK.

Due to the short path length of alpha particles in air, a detector that can be used at a distance from any potential radiological contamination reduces the time and hazard that traditional alpha detection methods incur. This would reduce costs and protect personnel in nuclear power generation and decommissioning activities, where alpha detection is crucial to full characterisation and contamination detection. Stand-off alpha detection could potentially be achieved by the detection of alpha-induced radioluminescence, especially in the ultraviolet C (UVC) wavelength range (180⁻280 nm) where natural and artificial background lighting is less likely to interfere with detection. Read More

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December 2018

One-Step Synthesis of Ag@TiO₂ Nanoparticles for Enhanced Photocatalytic Performance.

Nanomaterials (Basel) 2018 Dec 12;8(12). Epub 2018 Dec 12.

National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China.

Polyamide network polymers (PNP) modified TiO₂ nanoparticles (NPs) were decorated with Ag NPs in hydrothermal gel method, forming one-step synthesized photocatalysts, Ag@TiO₂ NPs. The effect of PNP and the amount of Ag NPs added were investigated in this work. PNP acted as a nanocage to prevent TiO₂ aggregation and capture Ag accurately, which could effectively control product sizes and improve dispersibility in solvents. Read More

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December 2018

Simultaneous Dual-mode Emission and Tunable Multicolor in the Time Domain from Lanthanide-doped Core-shell Microcrystals.

Nanomaterials (Basel) 2018 Dec 7;8(12). Epub 2018 Dec 7.

The Institute of Spectroscopy of the Russian Academy of Sciences, 142190 Moscow, Russia.

The dual-mode emission and multicolor outputs in the time domain from core-shell microcrystals are presented. The core-shell microcrystals, with NaYF₄:Yb/Er as the core and NaYF₄:Ce/Tb/Eu as the shell, were successfully fabricated by employing the hydrothermal method, which confines the activator ions into a separate region and minimizes the effect of surface quenching. The material is capable of both upconversion and downshifting emission, and their multicolor outputs in response to 980 nm near-infrared (NIR) excitation laser and 252 nm, and 395 nm ultraviolet (UV) excitation light have been investigated. Read More

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December 2018

Evaluation of a Push-Pull System for the Management of Species (Thysanoptera: Thripidae) in Tomato.

Insects 2018 Dec 7;9(4). Epub 2018 Dec 7.

US Horticultural Research Laboratory, USDA-ARS, Fort Pierce, FL 34945, USA.

A push-pull strategy for reducing populations of the thrips (Pergande), (Morgan) and (Fitch) in tomato was evaluated. Push components consisted of ultraviolet (UV)-reflective mulch and foliar applications of kaolin and the pull component consisted of the companion plant (L.). Read More

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December 2018

A COMPARATIVE STUDY OF EPR AND TL SIGNALS IN GORILLA® GLASS.

Radiat Prot Dosimetry 2018 Dec 13. Epub 2018 Dec 13.

Department of Nuclear Engineering, Institute for Nuclear Security, University of Tennessee, Knoxville, TN, USA.

Electron Paramagnetic Resonance (EPR) and Thermoluminescence (TL) signals have been studied in samples of Gorilla® Glass (GG) from different smartphones as well as some online stores and vendors. Background, radiation-induced and ultraviolet-induced signals were compared between the samples. Significant variability of both EPR and TL signals (in shape and intensity) was observed between samples from different screens as well as over the surface of the same screen, from the same phone. Read More

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December 2018

High-performance gas sensors based on single-wall carbon nanotube random networks for the detection of nitric oxide down to the ppb-level.

Nanoscale 2018 Dec 13. Epub 2018 Dec 13.

Department of Electronic Materials Engineering, Kwangwoon University, Seoul 139-701, Republic of Korea.

We demonstrate highly sensitive and selective gas sensors based on solution-processed single-wall carbon nanotube (SWCNT) random networks for the detection of nitric oxide (NO) down to the ppb-level operating at room temperature. The proposed gas sensors exhibited a response of 50% under both inert and air atmospheres with a theoretical detection limit of 0.2 ppb and a selectivity toward different target gases of volatile organic compounds, including benzene, toluene, and ammonia. Read More

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December 2018
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Triplet Harvesting by a Fluorescent Emitter using a Phosphorescent Sensitizer for Blue Organic Light-Emitting Diodes.

ACS Appl Mater Interfaces 2018 Dec 13. Epub 2018 Dec 13.

Development of highly efficient blue organic light-emitting diodes (OLEDs) with good stability is currently the most important issue in OLED displays and lighting. This paper reports an efficient blue fluorescent OLED based on a deep-blue emitting phosphorescent sensitizer ((dfpysipy)2Ir(mpic)) and a conventional fluorescent emitter (TBPe). Efficient triplet harvesting by the fluorescent emitter occurs in the OLED due to sensitization even though the difference in emission energy between the phosphorescent and fluorescent dyes was only 0. Read More

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December 2018

Solid-phase extraction coupled with switchable hydrophilicity solvent-based homogeneous liquid-liquid microextraction for chloramphenicol enrichment in environmental water samples: a novel alternative to classical extraction techniques.

Anal Bioanal Chem 2018 Dec 12. Epub 2018 Dec 12.

School of Pharmacy, Shenyang Pharmaceutical University, P.O. Box 54, 103 Wenhua Road, Shenyang, 110016, Liaoning, China.

A simple and efficient method combining solid-phase extraction (SPE) with homogeneous liquid-liquid microextraction (HLLME) has been developed for fast pretreatment of chloramphenicol (CAP) from water samples prior to determination by high-performance liquid chromatography-ultraviolet detection. Oasis HLB sorbent was chosen for SPE. In HLLME, N,N-dimethylcyclohexylamine was used as a CO-triggered switchable solvent that could switch reversibly between hydrophilic and hydrophobic forms. Read More

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December 2018

Direct synthesis of aryl-annulated []carbazoles by gold(i)-catalysed cascade reaction of azide-diynes and arenes.

Chem Sci 2018 Nov 10;9(44):8416-8425. Epub 2018 Sep 10.

Graduate School of Pharmaceutical Sciences , Kyoto University , Sakyo-ku , Kyoto 606-8501 , Japan . Email:

The gold-catalysed annulation of conjugated alkynes bearing an azido group with arenes gave annulated []carbazoles. Using benzene, pyrrole, and indole derivatives as the nucleophiles, benzo[]-, pyrrolo[2,3-]-, and indolo[2,3-]carbazoles were produced, respectively. The reaction proceeded through pyrrole and benzene ring construction accompanied by the formation of two carbon-carbon and one carbon-nitrogen bond and the cleavage of two aromatic C-H bonds. Read More

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November 2018

Alternate Soaking Technique for Micropatterning Alginate Hydrogels on Wettability-patterned Substrates.

J Oleo Sci 2018 Dec 12. Epub 2018 Dec 12.

Department of Materials Science and Technology, Tokyo University of Science.

Techniques for patterning hydrogels are important for fabrication of cell culture, analytical, and actuator devices at the micro- and nanometer length scales. In this study, we fabricated alginate hydrogels cross-linked by divalent cations on wettability-patterned substrates by alternate soaking of precursor solutions of sodium alginate and divalent cations. The wettability-patterned substrates were fabricated on hydrophilic glass plates modified with hydrophobic self-assembled monolayers of hexamethyldisilazane followed by exposure to an ultraviolet/ozone atmosphere through a metal mask. Read More

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December 2018

Comparative transcriptome analysis revealed the improved β-carotene production in Sporidiobolus pararoseus yellow mutant MuY9.

J Gen Appl Microbiol 2018 Dec 13. Epub 2018 Dec 13.

College of Land and Environment, Shenyang Agricultural University.

Carotenoids are ubiquitous constituents of living organisms. These structurally diverse pigments have received considerable attention due to their biotechnological applications and potential beneficial effects on human health. In this study, we characterized an over-producing β-carotene mutant of Sporidiobolus pararoseus, obtained by ultraviolet mutagenesis, named MuY9. Read More

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December 2018

Participatory action research, mixed methods, and research teams: learning from philosophically juxtaposed methodologies for optimal research outcomes.

BMC Med Res Methodol 2018 Dec 12;18(1):167. Epub 2018 Dec 12.

School of Social Science, University of the Sunshine Coast, Room D1.32, Locked Bag 4, Maroochydore DC, QLD, 4558, Australia.

Background: Workplace health interventions incorporating qualitative and quantitative components (mixed methods) within a Participatory Action Research approach can increase understanding of contextual issues ensuring realistic interventions which influence health behaviour. Mixed methods research teams, however, face a variety of challenges at the methodological and expertise levels when designing actions and interventions. Addressing these challenges can improve the team's functionality and lead to higher quality health outcomes. Read More

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December 2018

5-Aminolevulinic Acid-Based Photodynamic Therapy Pretreatment Mitigates Ultraviolet A-Induced Oxidative Photodamage.

Oxid Med Cell Longev 2018 7;2018:9420745. Epub 2018 Nov 7.

Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.

Aim: To determine whether 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) is effective in combating ultraviolet A- (UVA-) induced oxidative photodamage of hairless mice skin and human epidermal keratinocytes .

Methods: In experiments, the human keratinocyte cell line (HaCaT cells) was divided into two groups: the experimental group was treated with ALA-PDT and the control group was left untreated. Then, the experimental group and the control group of cells were exposed to 10 J/m of UVA radiation. Read More

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November 2018

Measurement of UV radiation in commercial aircraft.

J Radiol Prot 2018 Nov 21. Epub 2018 Nov 21.

Lufthansa German Airlines, Lufthansa Basis, Frankfurt/Main, GERMANY.

Ultraviolet Radiation (UVR) is significantly higher at aviation altitudes with respect to sea level. Cockpit windshields protect pilots from UV-B radiation but studies have shown that this is not necessarily the case for UV-A radiation. This work investigates the spectral properties of several windshields under flight conditions. Read More

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November 2018

Preferentially Oriented TiO2 Nanotube Arrays on Non-Native Substrates and Their Improved Performance as Electron Transporting Layer in Halide Perovskite Solar Cells.

Nanotechnology 2018 Oct 19. Epub 2018 Oct 19.

Electrical and Computer Engineering, University of Alberta, Edmonton, Alberta, CANADA.

Anodically formed TiO2 nanotube arrays (TNTAs) constitute an optoelectronic platform that is being studied for use as a photoanode in photoelectrocatalytic cells, as an electron transport layer (ETL) in solar cells and photodetectors, and as an active layer for chemiresistive and microwave sensors. For optimal transport of charge carriers in these one-dimensional polycrystalline ordered structures, it is desirable to introduce a preferential texture with the grains constituting the nanotube walls aligned along the transport direction. Through X-ray diffraction analysis, we demonstrate that choosing the right water content in the anodization electrolyte and the use of a post-anodization zinc ion treatment can introduce a preferential texture in sub-micron length transparent TNTAs formed on non-native substrates. Read More

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October 2018

Toward facile broadband photodetectors based on self-assembled ZnO nanobridge/rubrene heterointerface.

Nanotechnology 2019 Feb;30(6):065202

School of Electronic Science and Engineering and Collaborative Innovation Center of Solid State Lighting and Energy-saving Electronics, Nanjing University, Nanjing 210093, People's Republic of China.

ZnO nanowire photodetectors have attracted much attention due to their excellent optoelectronic performance. However, operating speed remains a challenge, and scalability is also impeded by uncontrolled transfer methods and sophisticated fabrication process. In this paper, we have fabricated an excellent ZnO nanobridge ultraviolet photodetector array by using a simple one-step method. Read More

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February 2019

Single-channel UV/Vis dual-band detection with ZnCdS:Mn/ZnS core/shell quantum dots.

Nanotechnology 2018 Nov 26. Epub 2018 Nov 26.

Southeast University, Nanjing, 210096, CHINA.

In an ultraviolet detection system, the Si-based photodetector could be sensitized with some kinds of fluorescent materials to enhance its response in the short-wavelength range. Thick-shell ZnCdS:Mn/ZnS core/shell quantum dots (QDs) exhibit unique advantage in UV signal sensitization due to their long PL lifetime, as well as stable emission matched with CCD's response. Herein, a single-channel UV panoramic detection system based on these Mn-doped QDs has been proposed. Read More

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November 2018

Electronic structure of an Iron-Porphyrin derivative on Au(111).

J Phys Condens Matter 2018 Nov 21. Epub 2018 Nov 21.

Physikalisch-Chemisches Institut, Ruprecht-Karls-Universit¨at Heidelberg, Heidelberg, GERMANY.

Surface-bound porphyrins are promising candidates for molecular switches, electronics and spintronics. Here, we studied the structural and the electronic properties of Fe-tetra-pyridil-porphyrin adsorbed on Au(111) in the monolayer regime. We combined scanning tunneling microscopy/spectroscopy, ultraviolet photoemission, and two-photon photoemission to determine the energy levels of the frontier molecular orbitals. Read More

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November 2018

Treatment of actinic keratosis through inhibition of cyclooxygenase-2: Potential mechanism of action of diclofenac sodium 3% in hyaluronic acid 2.5.

Dermatol Ther 2018 Dec 6:e12800. Epub 2018 Dec 6.

DISSAL Section of Dermatology, University of Genoa-IRCCS, AOU San Martino-IST, Genoa, Italy.

Cyclooxygenase-2 (COX-2) and its metabolic product prostaglandin E (PGE ) are induced in response to growth factors, inflammatory cytokines, tumour promoters, activated oncogenes and, in the skin, ultraviolet (UV) radiation. Accumulating evidence suggests a role for the COX-2/PGE pathway in tumourigenesis in various tissue types including cutaneous squamous cell carcinoma. There is also strong evidence for a role in the development of actinic keratoses (AKs) - common dysplastic lesions of the skin associated with UV radiation overexposure - considered as part of a continuum with skin cancer. Read More

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December 2018

Merkel Cell Carcinoma in the HIV-1/AIDS Patient.

Cancer Treat Res 2019 ;177:211-229

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215, USA.

Merkel cell carcinoma (MCC) is a highly aggressive, primary neuroendocrine cancer of the skin. The majority of MCC cases are associated with the recently discovered Merkel cell polyomavirus (MCPyV), while the remaining are caused by ultraviolet (UV) light-induced mutations from excessive sunlight exposure. The risk of developing MCC is much higher in the white population relative to all other races. Read More

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January 2019

Do ultraviolet photos increase sun safe behavior expectations via fear? A randomized controlled trial in a sample of U.S. adults.

J Behav Med 2018 Dec 6. Epub 2018 Dec 6.

Huntsman Cancer Institute, University of Utah, Salt Lake City, USA.

Ultraviolet (UV) photos reveal the world in a different light spectrum, including damage that is caused by UV light. In the context of skin cancer control, UV photos have the potential to communicate fear because they reveal underlying skin damage. U. Read More

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December 2018

Ground-based detection of an extended helium atmosphere in the Saturn-mass exoplanet WASP-69b.

Science 2018 Dec 6. Epub 2018 Dec 6.

Centro de Astrobiología (Consejo Superior de Investigaciones Científicas - Instituto Nacional de Técnica Aeroespacial, CSIC-INTA), Crta. de Ajalvir km 4, E-28850 Torrejón de Ardoz, Madrid, Spain.

Hot gas giant exoplanets can lose part of their atmosphere due to strong stellar irradiation, affecting their physical and chemical evolution. Studies of atmospheric escape from exoplanets have mostly relied on space-based observations of the hydrogen Lyman-α line in the far ultraviolet which is strongly affected by interstellar absorption. Using ground-based high-resolution spectroscopy we detect excess absorption in the helium triplet at 1083 nm during the transit of the Saturn-mass exoplanet WASP-69b, at a signal-to-noise ratio of 18. Read More

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December 2018
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Spectrally resolved helium absorption from the extended atmosphere of a warm Neptune-mass exoplanet.

Science 2018 Dec 6. Epub 2018 Dec 6.

Institut d'Astrophysique de Paris, CNRS, UMR 7095, Sorbonne Université, 98 bis boulevard Arago, F-75014, Paris, France.

Stellar heating causes atmospheres of close-in exoplanets to expand and escape. These extended atmospheres are difficult to observe because their main spectral signature-neutral hydrogen at ultraviolet wavelengths-is strongly absorbed by interstellar medium. We report the detection of the near-infrared triplet of neutral helium in the transiting warm Neptune-mass exoplanet HAT-P-11b using ground-based, high-resolution observations. Read More

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December 2018

Incidence and Determinants of Intraocular Lens Implantation in Type 2 Diabetes: The Fremantle Diabetes Study Phase II.

Diabetes Care 2018 Dec 6. Epub 2018 Dec 6.

Medical School, University of Western Australia, Fremantle Hospital, Fremantle, Western Australia, Australia.

Objective: To compare the incidence of intraocular lens (IOL) implantation for cataracts between people with and without type 2 diabetes and to determine associated risk factors in those with type 2 diabetes.

Research Design And Methods: Participants with type 2 diabetes ( = 1,499) from the community-based observational Fremantle Diabetes Study Phase II (FDS2) were age, sex, and zip code matched 1:4 with residents without diabetes. IOL implantation status was ascertained between entry (2008-2011) and the end of 2016 using validated data linkage. Read More

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December 2018

Keratinocyte Carcinomas: Current concepts and future research priorities.

Clin Cancer Res 2018 Dec 6. Epub 2018 Dec 6.

Department of Cancer Biology and Genetics and Division of Human Genetics, Department of Internal Medicine, Ohio State University

Cutaneous squamous cell carcinoma (cSCC) and basal cell carcinoma (BCC) are keratinocyte carcinomas (KC), the most frequently diagnosed cancers in fair-skinned populations. Ultraviolet radiation (UVR) is the main driving carcinogen for these tumors but immunosuppression, pigmentary factors, and aging are also risk factors. Scientific discoveries have improved the understanding of the role of human papillomaviruses (HPV) in cSCC as well as the skin microbiome and a compromised immune system in the development of both cSCC and BCC. Read More

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December 2018
8.722 Impact Factor

Brahma deficiency in keratinocytes promotes UV carcinogenesis by accelerating the escape from cell cycle arrest and the formation of DNA photolesions.

J Dermatol Sci 2018 Nov 22. Epub 2018 Nov 22.

Dermatology, Central Clinical School, and Bosch Institute, University of Sydney, Sydney, NSW, Australia; Centenary Institute, Cancer Services, Royal Prince Alfred Hospital, Dermatology, Bosch Institute, University of Sydney, Camperdown, NSW 2050, Australia. Electronic address:

Background: Ultraviolet radiation (UVR) is the principal cause of keratinocyte skin cancers. Previous work found that levels of the chromatin remodelling protein, Brahma (Brm), are diminished during the progression from actinic keratoses to cutaneous squamous cell carcinomas in humans, and its loss in UV-irradiated mouse skin causes epidermal hyperplasia and increased tumour incidence.

Methods: The skins of mice and mouse and human keratinocytes deficient in Brm were exposed to UVR and evaluated for cell cycle progression and DNA damage response. Read More

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November 2018

Ultraviolet functionalization improved bone integration on titanium surfaces by fluorescent analysis in rabbits calvarium.

J Oral Implantol 2018 Dec 12. Epub 2018 Dec 12.

5 Stomatological Hospital, Southern Medical University, Guangzhou, China.

This study evaluated the effect of ultraviolet functionalization (UV) on bone integration ability in rabbit model, using epifluorescence microscopy. Each of twelve rabbits (n=6) received randomly four titanium domes prepared with or without ultraviolet for 48 hours (UVC,λ= 250 ± 20 nm; Philips, Tokyo, Japan): (1) turned surface (T), (2) turned surface with UV(T-UV), (3) sandblasted (120 μm aluminum oxide) and etched by 18% hydrochloric acid and 49% sulphuric acid at 60°C for 30 min (SLA) and (4) SLA surface with UV(SLA-UV). Fluorochrome bone labels were marked by oxytetracycline at 25 mg/kg on 13th days and 14th days and calcein at 5 mg/kg on 3th days and 4th days before euthanization. Read More

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December 2018

A new multistep purification method for simultaneously determining organic ultraviolet absorbents in fish tissue.

Environ Monit Assess 2018 Dec 11;191(1):16. Epub 2018 Dec 11.

Key Laboratory of Trace Element Nutrition of National Health Commission, National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, 100021, China.

More information is required to improve our understanding of the presence of organic ultraviolet absorbents (UVAs) in organisms and the risks posed to biota. Effective removal of lipids in the determination of UVAs in biological samples is a sample-processing bottleneck. In this study, we optimized a multistep purification method for fish tissue samples extracted using an ultrasonic-assisted extraction method. Read More

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December 2018

The Response of Somatic Embryos to UV-B Radiation Depends on the Phase of Maturation.

Front Plant Sci 2018 27;9:1736. Epub 2018 Nov 27.

Institute of Experimental Botany of the Czech Academy of Sciences, Prague, Czechia.

Ultraviolet-B (UV-B) radiation is a key environmental signal which initiates diverse responses that affect the metabolism, development, and viability of plants. In keeping with our previous studies, we concentrated primarily on how UV-B radiation affects Norway spruce [ (L.) Karst. Read More

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November 2018
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Biogenic pentagonal silver nanoparticles for safer and more effective antibacterial therapeutics.

Int J Nanomedicine 2018 21;13:7789-7799. Epub 2018 Nov 21.

Nanomedicine & Nanobiotechnology Lab, Department of Biosciences, Integral University, Dasauli, Lucknow, India,

Background: Biological synthesis of nanomaterials possesses unprecedented potential in the production of nanomaterials due to their ability to produce nanomaterials with improved biocompatibility in addition to eco-friendly synthetic procedures.

Methods: This article reports the isolation of an air-borne fungus from the campus of Integral University, Lucknow, with an exceptional ability to withstand very high concentrations of silver salt. The fungus was found to produce pentagonal silver nanoparticles (AgPgNps) when silver ions were reduced from silver nitrate. Read More

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November 2018

Structural and functional comparability study of anti-CD20 monoclonal antibody with reference product.

Biologics 2018 23;12:159-170. Epub 2018 Nov 23.

Sun Pharmaceutical Industries Limited, Tandalja, Vadodara 390 012, India,

Background: Cell surface protein, CD20, is extensively expressed on the surface of B cells. Antibodies targeting CD20 protein are being used to treat B-cell malignancies and B-cell mediated autoimmune diseases. Considering the cost of therapy with innovator monoclonal antibodies for these diseases, development of biosimilar products for the treatment of such diseases provides affordable solution to rising healthcare costs. Read More

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November 2018

Ultrathin Conductor Enabling Efficient IR Light CO2 Reduction.

J Am Chem Soc 2018 Dec 12. Epub 2018 Dec 12.

Concurrent transformation of carbon dioxide and water into hydrocarbons and oxygen by low-photonic-energy IR light still represents a huge challenge. Here, we design an ultrathin conductor system, in which the special partially occupied band serves as the mediator to simultaneously guarantee IR light harvesting and satisfied band-edge positions, while the ultrathin configuration improves charge separation rates and surface redox kinetics. Taking the low cost and earth abundant CuS as an example, we first fabricate ultrathin CuS layers, where temperature-dependent resistivities, valence-band spectrum and theoretical calculation affirm their metallic nature. Read More

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December 2018

A review of methods used for hazard identification and risk assessment of environmental hazards.

Environ Int 2018 Dec 8;123:231-239. Epub 2018 Dec 8.

Department of Innovation, Evidence and Research, World Health Organization, Av. Appia 20 CH-1211, Geneva 27, Switzerland. Electronic address:

Background: Approximately one quarter of all deaths globally are attributed to living or working in an unhealthy environment, with household and ambient air pollution, along with exposures to ultraviolet radiation and chemicals amongst the leading causes. At present there are no international standards for assessing the risks of these environmental hazards. The use of heterogeneous methods to identify health risks from environmental hazards may reduce the level of confidence the public has in the conclusions that are made. Read More

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December 2018

Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials.

Exp Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Integrative Stem Cell Center, China Medical University Hospital, China Medical University, Taichung, 40402, Taiwan.

Skin evolves essential appendages and indispensable types of cells that synergistically insulate the body from environmental insults. Residing in the specific regions in the skin such as epidermis, dermis and hair follicle, melanocytes perform an array of vital functions including defending the ultraviolet radiation and diversifying animal appearance. As one of the adult stem cells, melanocyte stem cells in the hair follicle bulge niche can proliferate, differentiate, and keep quiescence to control and coordinate tissue homeostasis, repair, and regeneration. Read More

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December 2018
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Quality, bioactivity study, and preclinical acute toxicity, safety pharmacology evaluation of PEGylated recombinant human endostatin (M ES).

J Biochem Mol Toxicol 2018 Dec 10:e22257. Epub 2018 Dec 10.

National Engineering Laboratory for Anti-Tumor Protein Therapeutics, School of Life Sciences, Tsinghua University, Beijing, China.

Endostar, a potent endogenous antiangiogenic factor, is wildly used in clinics. However, it was easily degraded by enzymes and rapidly cleared by the kidneys. To overcome these shortcomings, PEGylated recombinant human endostatin was developed. Read More

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December 2018

Risk of skin cancer in psoriasis patients receiving long-term narrowband ultraviolet phototherapy: results from a Taiwanese population-based cohort study.

Photodermatol Photoimmunol Photomed 2018 Dec 10. Epub 2018 Dec 10.

Department of Dermatology, Taichung Veterans General Hospital, Taichung.

Background: Narrow-band ultraviolet B (NB-UVB) phototherapy is a widely used treatment for various dermatoses. The risk of skin cancer following long term NB-UVB phototherapy has rarely been explored in skin phototypes III-V.

Methods: We conducted a nationwide matched cohort study and identified a total of 22,891 psoriasis patients starting NB-UVB phototherapy from the Taiwan National Health Insurance Database during the period 2000-2013. Read More

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December 2018
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