223,633 results match your criteria Ultrasonography Cardiac


The POCUS Pulse Check: A Case Series on a Novel Method for Determining the Presence of a Pulse Using Point-of-Care Ultrasound.

J Emerg Med 2019 Apr 16. Epub 2019 Apr 16.

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.

Background: During cardiopulmonary resuscitation, pulse checks must be rapid and accurate. Despite the importance placed on the detection of a pulse, several studies have shown that health care providers have poor accuracy for detection of central pulses by palpation. To date, the use of point-of-care ultrasound (POCUS) in cardiac arrest has focused on the presence of cardiac standstill and diagnosing reversible causes of the arrest. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07364679193010
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http://dx.doi.org/10.1016/j.jemermed.2019.02.013DOI Listing
April 2019
1 Read

ST-segment elevation and cardiac magnetic resonance imaging findings in myocardial infarction with non-obstructive coronary arteries.

Int J Cardiol 2019 Apr 10. Epub 2019 Apr 10.

Soter Center for Women's Cardiovascular Research, Leon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, NY, United States of America. Electronic address:

Purpose: Patients with myocardial infarction and non-obstructive coronary arteries (MINOCA) may present with or without ST-elevation (STE) on the electrocardiogram (ECG). Previous studies have shown that STE was associated with higher risk of early mortality and long-term major adverse coronary events, and that cardiac magnetic resonance imaging (CMR) can help to determine whether the cause of a MINOCA presentation is ischemic or non-ischemic. We set out to determine the relationship between STE and CMR findings in patients presenting with MINOCA. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.04.028DOI Listing

Association of Echocardiographic Parameters of Right Ventricular Remodeling and Myocardial Performance With Modified Task Force Criteria in Adolescents With Arrhythmogenic Right Ventricular Cardiomyopathy.

Circ Cardiovasc Imaging 2019 Apr;12(4):e007693

Department of Pediatrics, Labatt Family Heart Centre (G.E.P., L.G.-W., M.H., M.F., P.C., C.S., W.H., C.-P.S.F., C.M., L.M., R.H., M.K.F.), Hospital for Sick Children, University of Toronto, ON, Canada.

Background: The usefulness of echocardiographic indices, including those already used by modified Task Force Criteria (mTFC), and others such as strain imaging, to identify arrhythmogenic right ventricular cardiomyopathy (ARVC) in adolescence is not well established.

Methods: Echocardiograms from 120 adolescents investigated for ARVC (13±4 years) were retrospectively analyzed. According to the mTFC, patients were classified into definite (n=38), borderline (n=39), or possible (n=43) ARVC. Read More

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http://dx.doi.org/10.1161/CIRCIMAGING.118.007693DOI Listing

Left Ventricular Twist Mechanics to Identify Left Ventricular Noncompaction in Childhood.

Circ Cardiovasc Imaging 2019 Apr;12(4):e007805

Department of Paediatric Cardiology, Royal Brompton Hospital, London, United Kingdom (J.S., G.D.S., S.K., A.F., C.P., V.B., M.J., J.P., D.S., I.V., S.P., P.D.).

Background: Left ventricular noncompaction cardiomyopathy (LVNC) is associated with poor clinical outcome in childhood. Standard diagnostic criteria are still controversial, especially in young patients. Recent studies in adults demonstrated that left ventricular (LV) twist is abnormal in LVNC, but it has not been investigated in pediatric patients to date. Read More

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.118.0078
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http://dx.doi.org/10.1161/CIRCIMAGING.118.007805DOI Listing
April 2019
1 Read

Effect of IL-6-mediated STAT3 signaling pathway on myocardial apoptosis in mice with dilated cardiomyopathy.

Eur Rev Med Pharmacol Sci 2019 Apr;23(7):3042-3050

Department of Geriatrics, Quanzhou First Hospital of Fujian Medical University, Quanzhou, China.

Objective: To investigate the effect of interleukin-6 (IL-6) gene knockout on apoptosis of myocardial cells in mice with Coxsackievirus B3 (CVB3)-induced dilated cardiomyopathy (DCM) and its potential mechanism, so as to provide certain references for the clinical prevention and treatment of DCM.

Materials And Methods: A total of 40 male C57 mice were randomly divided into Sham group (n=20) and DCM group (n=20) using a random number table. Another 20 mice with IL-6 gene knockout were enrolled into DCM+IL-6 KO group (n=20). Read More

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http://www.europeanreview.org/article/17586
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http://dx.doi.org/10.26355/eurrev_201904_17586DOI Listing
April 2019
2 Reads

Early signs of middle cerebral artery infarction on multidetector computed tomography: Review of 20 cases.

Brain Circ 2019 Jan-Mar;5(1):27-31. Epub 2019 Mar 27.

Department of Diagnostic Radiologic Technology, College of Applied Medical Sciences, Taibah University, Almadinah Almunawarah, Medina, Saudi Arabia.

Objective: This study intended to assess the occurrence of early signs of middle cerebral artery (MCA) on multidetector computed tomography (MDCT) in correlation with duration of the clinical features of stroke.

Patients And Methods: This retrospective study analyzed the electronic records of 20 patients with MCA infarction. The detected signs studied according to the onset of the clinical features of stroke to the time of CT imaging. Read More

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http://dx.doi.org/10.4103/bc.bc_28_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458774PMC

Right Heart Mass in Transit with a Hemorrhagic Pericardial Effusion: A Diagnostic Dilemma.

Cureus 2019 Feb 4;11(2):e4009. Epub 2019 Feb 4.

Cardiology, Washington University, Saint Louis, USA.

Metastatic disease to the heart is more often a post-mortem diagnosis due to non-specific symptoms and a low index of suspicion. Our case is a unique presentation of a rare case of cardiac metastasis from oropharyngeal cancer, which eluded echocardiographic diagnosis despite the presence of a hemorrhagic pericardial effusion. The cardiac metastasis, in fact, starts as pericardial seeding, as illustrated by the positron emission tomography (PET) imaging. Read More

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http://dx.doi.org/10.7759/cureus.4009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450589PMC
February 2019

Sampling Rate Effects on Resting State fMRI Metrics.

Front Neurosci 2019 2;13:279. Epub 2019 Apr 2.

Oulu Functional NeuroImaging Group, Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland.

Low image sampling rates used in resting state functional magnetic resonance imaging (rs-fMRI) may cause aliasing of the cardiorespiratory pulsations over the very low frequency (VLF) BOLD signal fluctuations which reflects to functional connectivity (FC). In this study, we examine the effect of sampling rate on currently used rs-fMRI FC metrics. Ultra-fast fMRI magnetic resonance encephalography (MREG) data, sampled with TR 0. Read More

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https://www.frontiersin.org/article/10.3389/fnins.2019.00279
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http://dx.doi.org/10.3389/fnins.2019.00279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454039PMC
April 2019
2 Reads

Ultrasonography and X-Ray guided drain placement to evacuate a pneumopericardium/pneumomediastinum in a 1-day-old infant.

Indian J Radiol Imaging 2019 Jan-Mar;29(1):94-97

Children's Hospital Cardiology Center, Women's and Children's Hospital, University of Missouri Health Care, Columbia, USA.

Ultrasonographic (US) guided procedures have wide range of application in the abdomen and pelvis, however their role is somewhat limited in the chest due to complete reflection of the ultrasound beam by the air in the lungs, preventing the direct imaging of the tissues deep to the air-sound interface. Most of the chest procedures, other than the exception of thoracentesis, rely on the use of CT (computed tomography) scan. The disadvantages of using CT scan is the cost, lack of portability, and most importantly the radiation involved, particularly in case of infants and children, whose tissues are more radiosensitive than the adults. Read More

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http://dx.doi.org/10.4103/ijri.IJRI_447_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467035PMC

The Netherlands Arrhythmogenic Cardiomyopathy Registry: design and status update.

Neth Heart J 2019 Apr 17. Epub 2019 Apr 17.

Durrer Centre for Cardiovascular Research, Netherlands Heart Institute, Utrecht, The Netherlands.

Background: Clinical research on arrhythmogenic cardiomyopathy (ACM) is typically limited by small patient numbers, retrospective study designs, and inconsistent definitions.

Aim: To create a large national ACM patient cohort with a vast amount of uniformly collected high-quality data that is readily available for future research.

Methods: This is a multicentre, longitudinal, observational cohort study that includes (1) patients with a definite ACM diagnosis, (2) at-risk relatives of ACM patients, and (3) ACM-associated mutation carriers. Read More

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http://link.springer.com/10.1007/s12471-019-1270-1
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http://dx.doi.org/10.1007/s12471-019-1270-1DOI Listing
April 2019
1 Read

Cardiovascular health technology assessment: recommendations to improve the quality of evidence.

Open Heart 2019 27;6(1):e000930. Epub 2019 Feb 27.

BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

The aim of this article is to review the role of Health Technology Assessment (HTA) organisations in appraising and recommending innovative cardiovascular technologies. We consider how bias impairs the quality of evidence from clinical trials involving cardiovascular healthcare technologies. Finally, we provide recommendations to HTA organisations to take account of bias when making guideline recommendations. Read More

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http://dx.doi.org/10.1136/openhrt-2018-000930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443128PMC
February 2019

Appearance of myocardial fibrosis during long-term follow up in a patient with apical hypertrophy.

J Cardiol Cases 2019 Apr 21;19(4):115-116. Epub 2018 Dec 21.

Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.

A 67-year-old man without symptoms presented with significant negative T wave on electrocardiography. No significant abnormality was detected by echocardiography. Cardiac magnetic resonance imaging (CMR) showed trivial hypertrophied myocardium in apex. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18785409183011
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http://dx.doi.org/10.1016/j.jccase.2018.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451050PMC
April 2019
1 Read

Non-Invasive Imaging in Diabetic Cardiomyopathy.

Authors:
Ify R Mordi

J Cardiovasc Dev Dis 2019 Apr 16;6(2). Epub 2019 Apr 16.

Division of Molecular and Clinical Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK.

There is increasing recognition of a specific diabetic cardiomyopathy beyond ischemic cardiomyopathy, which leads to structural and functional myocardial abnormalities. The aim of this review is to summarize the recent literature on diagnostic findings and prognostic significance of non-invasive imaging including echocardiography, nuclear imaging, computed tomography and cardiovascular magnetic resonance in diabetic cardiomyopathy. Read More

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https://www.mdpi.com/2308-3425/6/2/18
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http://dx.doi.org/10.3390/jcdd6020018DOI Listing
April 2019
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Role of Cardiac Computed Tomography in the Diagnosis of Left Ventricular Myocardial Diseases.

J Cardiovasc Imaging 2019 Apr;27(2):73-92

Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Multimodality imaging is indicated for the evaluation of left ventricular (LV) myocardial diseases. Cardiac magnetic resonance (CMR) allows morphological and functional assessment of the LV along with soft tissue characterization. Technological advances in cardiac computed tomography (CT) have led to the development of techniques for diagnostic acquisition in LV myocardial disease. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4250/jcvi.2019.2
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http://dx.doi.org/10.4250/jcvi.2019.27.e17DOI Listing
April 2019
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MRI Evaluation of Suspected Pathologic Fracture at the Extremities from Metastasis: Diagnostic Value of Added Diffusion-Weighted Imaging.

Korean J Radiol 2019 May;20(5):812-822

Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Objective: To assess the diagnostic value of combining diffusion-weighted imaging (DWI) with conventional magnetic resonance imaging (MRI) for differentiating between pathologic and traumatic fractures at extremities from metastasis.

Materials And Methods: Institutional Review Board approved this retrospective study and informed consent was waived. This study included 49 patients each with pathologic and traumatic fractures at extremities. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3348/kjr.2018.05
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http://dx.doi.org/10.3348/kjr.2018.0545DOI Listing
May 2019
1 Read

Diagnostic accuracy of left atrial remodelling and natriuretic peptide levels for preclinical heart failure.

ESC Heart Fail 2019 Apr 16. Epub 2019 Apr 16.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.

Aims: Left atrial (LA) remodelling is an important predictor of cardiovascular events of heart failure (HF) and atrial fibrillation. Data regarding diagnostic value of LA remodelling on diastolic dysfunction (DD) and preclinical HF remain largely unexplored.

Methods And Results: We assessed LA dimension (LAD) in 8368 consecutive asymptomatic Asians (mean age: 49. Read More

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http://dx.doi.org/10.1002/ehf2.12430DOI Listing
April 2019
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Multimodality Imaging for the Assessment of Pericardial Diseases.

Curr Cardiol Rep 2019 Apr 16;21(5):41. Epub 2019 Apr 16.

Heart and Vascular Institute, Center for the Diagnosis and Treatment of Pericardial Disease, Cleveland Clinic, Cleveland, OH, USA.

Purpose Of Review: The diagnosis of pericardial syndromes, while occasionally straightforward, includes a wide range of pathologies and is often a well-recognized clinical challenge. The aim of this review is to highlight the key role of the various imaging modalities for the diagnosis and management of the spectrum of pericardial diseases.

Recent Findings: Cardiac imaging has become an integral part of the diagnostic process often beginning with echocardiography and supported by advanced imaging modalities including computed tomography, magnetic resonance imaging, and positive emission tomography. Read More

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http://link.springer.com/10.1007/s11886-019-1115-y
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http://dx.doi.org/10.1007/s11886-019-1115-yDOI Listing
April 2019
2 Reads

Visit-to-visit fasting plasma glucose variability is an important risk factor for long-term changes in left cardiac structure and function in patients with type 2 diabetes.

Cardiovasc Diabetol 2019 Apr 16;18(1):50. Epub 2019 Apr 16.

Department of Endocrinology & Metabosim, Guangdong Provincial Key Laboratory of Diabetology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, China.

Background: To investigate the effect of visit-to-visit fasting plasma glucose (FPG) variability on the left cardiac structure and function in patients with type 2 diabetes mellitus (T2DM).

Methods: In this prospective cohort study, 455 T2DM patients were included and follow-up for a median of 4.7 years. Read More

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https://cardiab.biomedcentral.com/articles/10.1186/s12933-01
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http://dx.doi.org/10.1186/s12933-019-0854-9DOI Listing
April 2019
1 Read

[The Clinical use of Stress Echocardiography in Ischemic Heart Disease Cardiovascular Ultrasound (2017)15:7. Translation authors: Arystan A.Zh., Fettser D.V.]

Kardiologiia 2019 Apr 13;59(3):78-96. Epub 2019 Apr 13.

City Clinical Hospital №52 Moscow.

Stress echocardiography is an established technique for the assessment of extent and severity of coronary artery disease. The combination of echocardiography with a physical, pharmacological or electrical stress allows detecting myocardial ischemia with an excellent accuracy. A transient worsening of regional function during stress is the hallmark of inducible ischemia. Read More

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https://lib.ossn.ru/jour/article/view/579
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http://dx.doi.org/10.18087/cardio.2019.3.10244DOI Listing
April 2019
2 Reads

Heart failure in cardiomyopathies: a position paper from the Heart Failure Association of the European Society of Cardiology.

Eur J Heart Fail 2019 Apr 16. Epub 2019 Apr 16.

Berlin-Brandenburg Center for Regenerative Therapies, Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) Berlin, Department of Cardiology, Campus Virchow Klinikum, Charite - Universitaetsmedizin Berlin, Berlin, Germany.

Cardiomyopathies are a heterogeneous group of heart muscle diseases and an important cause of heart failure (HF). Current knowledge on incidence, pathophysiology and natural history of HF in cardiomyopathies is limited, and distinct features of their therapeutic responses have not been systematically addressed. Therefore, this position paper focuses on epidemiology, pathophysiology, natural history and latest developments in treatment of HF in patients with dilated (DCM), hypertrophic (HCM) and restrictive (RCM) cardiomyopathies. Read More

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http://dx.doi.org/10.1002/ejhf.1461DOI Listing
April 2019
2 Reads
6.526 Impact Factor

CONTEMPORARY RADIATION DOSES IN INTERVENTIONAL CARDIOLOGY: A NATIONWIDE STUDY OF PATIENT DOSES IN FINLAND.

Radiat Prot Dosimetry 2019 Apr 16. Epub 2019 Apr 16.

Department of Medical Physics, Turku University Hospital, Turku, Finland.

The amount of interventional procedures such as percutaneous coronary intervention (PCI), transcatheter aortic valve implantation (TAVI), pacemaker implantation (PI) and ablations has increased within the previous decade. Simultaneously, novel fluoroscopy mainframes enable lower radiation doses for patients and operators. Therefore, there is a need to update the existing diagnostic reference levels (DRLs) and propose new ones for common or recently introduced procedures. Read More

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http://dx.doi.org/10.1093/rpd/ncz041DOI Listing
April 2019
1 Read

High-Sensitivity Cardiac Troponin I Assay for Early Diagnosis of Acute Myocardial Infarction.

Clin Chem 2019 Apr 15. Epub 2019 Apr 15.

Cardiovascular Research Institute Basel (CRIB) and Department of Cardiology, University Hospital Basel, University of Basel, Basel, Switzerland;

Background: The aim of this study was to validate the clinical performance of the Beckman Access high-sensitivity cardiac troponin I (hs-cTnI) assay.

Methods: We enrolled patients presenting to the emergency department with symptoms suggestive of acute myocardial infarction (AMI). Final diagnoses were centrally adjudicated by 2 independent cardiologists with all clinical information including cardiac imaging twice: first, using serial hs-cTnT (Elecsys, primary analysis), and second, using hs-cTnI (Architect, secondary analysis) measurements in addition to the clinically used hs-cTn. Read More

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http://dx.doi.org/10.1373/clinchem.2018.300061DOI Listing
April 2019
1 Read

Non-ST elevation myocardial infarction induced by carbon monoxide poisoning: A case report.

Medicine (Baltimore) 2019 Apr;98(15):e15151

Department of Cardiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing.

Rationale: Acute myocardial infarction is a rare complication of carbon monoxide poisoning. there is often no chest pain and other typical manifestations. We report a patient with mild carbon monoxide poisoning who had acute dyspnea as the earliest symptom and was later diagnosed with non-ST elevation myocardial infarction (NSTEMI) and acute left heart failure. Read More

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http://Insights.ovid.com/crossref?an=00005792-201904120-0005
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http://dx.doi.org/10.1097/MD.0000000000015151DOI Listing
April 2019
4 Reads

Impact of a decreasing pre-test probability on the performance of diagnostic tests for coronary artery disease.

Eur Heart J Cardiovasc Imaging 2019 Apr 14. Epub 2019 Apr 14.

Turku PET Centre, University of Turku and Turku University Hospital, Kiinamyllynkatu 4-8, 20520, Turku, Finland.

Aims: To provide a pooled estimation of contemporary pre-test probabilities (PTPs) of significant coronary artery disease (CAD) across clinical patient categories, re-evaluate the utility of the application of diagnostic techniques according to such estimates, and propose a comprehensive diagnostic technique selection tool for suspected CAD.

Methods And Results: Estimates of significant CAD prevalence across sex, age, and type of chest pain categories from three large-scale studies were pooled (n = 15 815). The updated PTPs and diagnostic performance profiles of exercise electrocardiogram, invasive coronary angiography, coronary computed tomography angiography (CCTA), positron emission tomography (PET), stress cardiac magnetic resonance (CMR), and SPECT were integrated to define the PTP ranges in which ruling-out CAD is possible with a post-test probability of <10% and <5%. Read More

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https://academic.oup.com/ehjcimaging/advance-article/doi/10.
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http://dx.doi.org/10.1093/ehjci/jez054DOI Listing
April 2019
2 Reads

Coronary Microvascular Dysfunction: Clinical Considerations and Noninvasive Diagnosis.

JACC Cardiovasc Imaging 2019 Apr 11. Epub 2019 Apr 11.

University of Maryland School of Medicine, Department of Diagnostic Radiology and Nuclear Medicine, Baltimore, Maryland.

Chest pain in patients without obstructive coronary artery disease has been realized as a frequent problem encountered in clinical practice. Invasive flow investigations have suggested that up to two-thirds of patients with nonobstructive coronary atherosclerosis may have microvascular dysfunction (MVD). Positron emission tomography myocardial perfusion imaging in conjunction with tracer-kinetic modeling enables the concurrent quantification of myocardial blood flow (MBF) in milliliters per minute per gram of tissue. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.11.036DOI Listing
April 2019
1 Read

Impact of nuclear imaging on diagnosis and management of infective endocarditis.

Acta Cardiol 2019 Apr 13:1-5. Epub 2019 Apr 13.

b Department of Cardiovascular Medicine , University Hospitals Leuven , Leuven , Belgium.

Background: Embolisation and metastatic infection occur frequently in infective endocarditis (IE). We aimed to evaluate the impact of nuclear imaging on diagnosis, therapy and mortality.

Methods: All patients hospitalised for definite IE at the University Hospitals of Leuven in 2001 and in 2015 were retrospectively included. Read More

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http://dx.doi.org/10.1080/00015385.2019.1595268DOI Listing
April 2019
1 Read

Anticoagulation therapy and the risk of perioperative brain injury in neonates with congenital heart disease.

J Thorac Cardiovasc Surg 2019 Feb 26. Epub 2019 Feb 26.

Division of Neurology, Department of Pediatrics, The Hospital for Sick Children and The University of Toronto, Toronto, Ontario, Canada; British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada. Electronic address:

Objective: There is considerable variability in anticoagulation use in neonates with transposition of the great arteries (TGA) and single ventricle physiology (SVP) for secondary stroke prevention and primary cardiovascular indications. Leveraging cross-center differences in anticoagulation use, we compared the risk of new postoperative brain injury in neonates with TGA and SVP treated with anticoagulation relative to untreated neonates.

Methods: Two-center observational cohort study of 118 term-born neonates with TGA (n = 83) and SVP (n = 35), undergoing cardiopulmonary bypass surgery and pre- and postoperative brain magnetic resonance imaging. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2019.02.029DOI Listing
February 2019
1 Read

Trends in mass spectrometry imaging for cardiovascular diseases.

Anal Bioanal Chem 2019 Apr 12. Epub 2019 Apr 12.

Maastricht MultiModal Molecular Imaging (M4I) Institute, Division of Imaging Mass Spectrometry, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

Mass spectrometry imaging (MSI) is a widely established technology; however, in the cardiovascular research field, its use is still emerging. The technique has the advantage of analyzing multiple molecules without prior knowledge while maintaining the relation with tissue morphology. Particularly, MALDI-based approaches have been applied to obtain in-depth knowledge of cardiac (dys)function. Read More

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http://dx.doi.org/10.1007/s00216-019-01780-8DOI Listing

Letter in response to the article entitled "Prognosis of severe congenital heart diseases: Do we overestimate the impact of prenatal diagnosis?" by Vincenti et al.

Arch Cardiovasc Dis 2019 Apr 9. Epub 2019 Apr 9.

Paediatric and congenital cardiology unit, Bordeaux university hospital, 33604 Pessac, France; IHU Lyric, electrophysiology and heart modelling institute, Fondation Bordeaux université, 33600 Pessac, France.

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http://dx.doi.org/10.1016/j.acvd.2019.03.002DOI Listing

Histopathological comparison of intramural coronary artery remodeling and myocardial fibrosis in obstructive versus end-stage hypertrophic cardiomyopathy.

Int J Cardiol 2019 Mar 28. Epub 2019 Mar 28.

Cardiovascular Pathology Unit, Department of Pathology, Sant'Orsola-Malpighi University Hospital, Bologna, Italy.

Background: Although imaging techniques have demonstrated the existence of microvascular abnormalities in hypertrophic cardiomyopathy (HCM), a detailed histopathological assessment is lacking as well as a comparison between different phases of the disease. We aimed to compare microvasculopathy and myocardial fibrosis in hypertrophic obstructive cardiomyopathy (HOCM) versus end-stage (ES) HCM.

Methods: 27 myectomy specimens of HOCM patients and 30 ES-HCM explanted hearts were analyzed. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.03.060DOI Listing
March 2019
2 Reads

Risk Analysis of Perioperative Death in Lung Transplant Patients With Severe Idiopathic Pulmonary Hypertension.

Transplant Proc 2019 Apr 8;51(3):875-879. Epub 2019 Jan 8.

Department of Lung Transplantation, Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province, China. Electronic address:

Objective: To investigate the risk factors for perioperative mortality in patients with severe idiopathic pulmonary hypertension (IPAH) undergoing lung transplantation (LTx).

Methods: Twenty-two IPAH patients were included in the study and were divided 2 groups: a case group with early death post LTx (n = 5, 22.7%) and the remaining 17 recipients (87. Read More

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http://dx.doi.org/10.1016/j.transproceed.2019.01.024DOI Listing
April 2019
1 Read

Cardiac left ventricular myocardial tissue density, evaluated by computed tomography and autopsy.

BMC Med Imaging 2019 04 12;19(1):29. Epub 2019 Apr 12.

Section of Forensic Pathology, Department of Forensic Medicine, University of Copenhagen, Frederik V's vej 11, 1 sal, 2100, Copenhagen, Denmark.

Background: Left ventricular mass (LVM) is an independent risk factor for the prediction of cardiac events. Its assessment is a clinically important diagnostic procedure in cardiology and may be performed by Computed Tomography (CT). The aim of this study was to assess the correlation between the cardiac left ventricular shell volume (LVShV) determined by postmortem Computed Tomography (PMCT) and the anatomic LVM obtained at autopsy and to calculate the myocardial tissue density. Read More

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https://bmcmedimaging.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12880-019-0326-4DOI Listing
April 2019
2 Reads

Caffeine Accelerates Cystic Kidney Disease in a Pkd1-Deficient Mouse Model.

Cell Physiol Biochem 2019 ;52(5):1061-1074

Nephrology Division, Universidade Federal de São Paulo, São Paulo, Brazil.

Background/aims: Autosomal dominant polycystic kidney disease (ADPKD) is characterized by progressive cyst formation and growth, leading to end-stage renal disease. A higher kidney volume is predictive of a more accelerated decline in renal function. This study aimed to examine the effects of caffeine, a phosphodiesterase inhibitor, on the progression of cystic kidney disease in a mouse model orthologous to human disease (Pkd1:Nestin). Read More

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http://dx.doi.org/10.33594/000000072DOI Listing
January 2019
1 Read

Effect of cardiac resynchronization therapy on septal perfusion and septal thickening: Association with left ventricular function, reverse remodelling and dyssynchrony.

J Nucl Cardiol 2019 Apr 11. Epub 2019 Apr 11.

Emory University, Atlanta, United States of America.

Background: We evaluated the effect of cardiac resynchronization therapy (CRT) on septal perfusion and thickening at 6 months post implantation assessed on Tc99m-MIBI Gated myocardial perfusion SPECT (GMPS).We also studied the association of change in septal perfusion and thickening with primary outcome defined as at least one [improvement in ≥1NYHA class, left ventricular ejection fraction (LVEF) by ≥ 5%, reduction of end-systolic volume (ESV) by ≥ 15%, and improvement ≥ 5 points in Minnesota living with heart failure questionnaire (MLHFQ)].

Method: One hundred and five patients underwent clinical and GMPS evaluation before and at 6 months post CRT. Read More

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http://dx.doi.org/10.1007/s12350-019-01704-0DOI Listing

High shear stress on the coronary arterial wall is related to computed tomography-derived high-risk plaque: a three-dimensional computed tomography and color-coded tissue-characterizing intravascular ultrasonography study.

Heart Vessels 2019 Apr 11. Epub 2019 Apr 11.

Division of Cardiology, Department of Medicine, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho Itabashi-ku, Tokyo, 173-8610, Japan.

Low wall shear stress (WSS) is associated with plaque formation. However, the relationship between WSS and coronary plaque vulnerability remains unclear. Therefore, this study aimed to clarify the in vivo relationship between luminal WSS derived from three-dimensional (3D) computed tomography (CT) and plaque vulnerability within the coronary artery. Read More

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http://dx.doi.org/10.1007/s00380-019-01389-yDOI Listing

Uninterrupted edoxaban vs. vitamin K antagonists for ablation of atrial fibrillation: the ELIMINATE-AF trial.

Eur Heart J 2019 Apr 11. Epub 2019 Apr 11.

Department of Cardiology, Institute for Clinical and Experimental Medicine, Videnska 1958/9, 140 21 Prague, Czech Republic.

Aims: Edoxaban is a direct factor Xa inhibitor approved for stroke prevention in atrial fibrillation (AF). Uninterrupted edoxaban therapy in patients undergoing AF ablation has not been tested.

Methods And Results: The ELIMINATE-AF trial, a multinational, multicentre, randomized, open-label, parallel-group study, was conducted to assess the safety and efficacy of once-daily edoxaban 60 mg (30 mg in patients indicated for dose reduction) vs. Read More

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http://dx.doi.org/10.1093/eurheartj/ehz190DOI Listing
April 2019
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Diagnosis of infective endocarditis with cardiac CT in an adult.

Radiol Case Rep 2019 May 25;14(5):544-547. Epub 2019 Feb 25.

Department of Cardiology, Chiba-Nishi General Hospital, 107-1 Kanegasaku, Matsudo, Chiba 270-2251, Japan.

The diagnosis of infective endocarditis is based on modified Duke's criteria, which includes clinical, biological, and echocardiographic findings. However, computed tomography (CT) has not been mentioned as a diagnostic tool in the criteria. We report a case of infective endocarditis confirmed by cardiac CT in which we could identify vegetations and perivalvular abscess not on transthoracic echocardiography and transesophageal echocardiography. Read More

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http://dx.doi.org/10.1016/j.radcr.2019.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443909PMC
May 2019
1 Read

Efficacy of endovascular thrombectomy in patients with M2 segment middle cerebral artery occlusions: meta-analysis of data from the HERMES Collaboration.

J Neurointerv Surg 2019 Apr 11. Epub 2019 Apr 11.

Department of Diagnostic Imaging, University of Calgary, Calgary, Alberta, Canada.

Background: The Society of Neurointerventional Surgery revised its operational definition of emergent large vessel occlusion (ELVO) recently to include proximal M2 segment middle cerebral artery (MCA) occlusions. We sought to assess the benefit of endovascular thrombectomy (EVT) over best medical care for M2 segment MCA occlusion.

Methods: Patient level data from trials in the HERMES Collaboration were included. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014678DOI Listing
April 2019
1 Read

Overview of complications of acute and chronic myocardial infarctions: revisiting pathogenesis and cross-sectional imaging.

Postgrad Med J 2019 Apr 11. Epub 2019 Apr 11.

Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

Myocardial infarction (MI) remains one of the leading contributors to overall mortality and morbidity in the modern world, even with recent advances in medicine. Various complications can arise following an MI, particularly with delayed or inadequate treatment. Even though many of these complications are uncommon, they can have a significant impact on patient outcomes. Read More

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http://dx.doi.org/10.1136/postgradmedj-2018-136279DOI Listing
April 2019
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The Effects of Equine Assisted Therapy on Plasma Cortisol and Oxytocin Concentrations and Heart Rate Variability in Horses and Measures of Symptoms of Post-Traumatic Stress Disorder in Veterans.

J Equine Vet Sci 2018 May 12;64:17-26. Epub 2018 Feb 12.

Rutgers Equine Science Center and the Department of Animal Sciences, Rutgers, The State University of New Jersey, New Brunswick, NJ.

With the increase in the number of horses being used in Equine-Assisted Activities and Therapies (EAAT) programs and with the increasing concern for animal welfare, it is important to understand the impact of such interventions on the stress level and quality of life for the horses involved. The purpose of the present pilot study was to test the hypothesis that participation in EAAT would acutely alter physiological markers of stress and well-being, including plasma cortisol, plasma oxytocin, and heart rate variability (HRV), in horses and that symptoms of posttraumatic stress disorder (PTSD) would be reduced after five sessions of EAAT in veterans who had previously been diagnosed with PTSD. Nine healthy geldings, of various breeds, ages 10-23 years, conditioned and experienced as therapeutic riding horses, were selected to participate in the study. Read More

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http://dx.doi.org/10.1016/j.jevs.2018.01.011DOI Listing
May 2018
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Type 2 Autoimmune Pancreatitis (Idiopathic Duct-Centric Pancreatitis) Highlighting Patients Presenting as Clinical Acute Pancreatitis: A SingleCenter Experience.

Gut Liver 2019 Apr 17. Epub 2019 Apr 17.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background/aims: : Type 2 autoimmune pancreatitis (AIP) has been considered extremely rare in East Asia. This study aimed to clarify the prevalence, clinical characteristics and radiological findings of type 2 AIP highlighting patients presenting as acute pancreatitis in a single center.

Methods: : Type 2 AIP patients were classified according to International Consensus Diagnostic Criteria. Read More

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http://dx.doi.org/10.5009/gnl18429DOI Listing
April 2019
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Metabolism of hyperpolarized C-acetoacetate to β-hydroxybutyrate detects real-time mitochondrial redox state and dysfunction in heart tissue.

NMR Biomed 2019 Apr 10:e4091. Epub 2019 Apr 10.

Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, Texas.

Mitochondrial dysfunction is considered to be an important component of many metabolic diseases yet there is no reliable imaging biomarker for monitoring mitochondrial damage in vivo. A large prior literature on inter-conversion of β-hydroxybutyrate and acetoacetate indicates that the process is mitochondrial and that the ratio reflects a specifically mitochondrial redox state. Therefore, the conversion of [1,3- C]acetoacetate to [1,3- C]β-hydroxybutyrate is expected to be sensitive to the abnormal redox state present in dysfunctional mitochondria. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/nbm.4091
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http://dx.doi.org/10.1002/nbm.4091DOI Listing
April 2019
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Effect of uric acid serum levels on carotid arterial stiffness and intima-media thickness: A high resolution Echo-Tracking Study.

Monaldi Arch Chest Dis 2019 Mar 27;89(1). Epub 2019 Mar 27.

Highly Specialized Rehabilitation Hospital in Motta Di Livenza, Cardiac Prevention and Rehabilitation Unit.

Serum uric acid (UA) has been shown to be a predictor of cardiovascular (CV) morbidity and mortality, and it may play a role in the pathogenesis of CV disease affecting vascular structure and function. However, there is limited evidence of its specific association with carotid artery stiffness and structure. The aim of our study was to evaluate whether UA is associated with early signs of atherosclerosis, namely local carotid arterial stiffness and intima-media thickening. Read More

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http://dx.doi.org/10.4081/monaldi.2019.1007DOI Listing
March 2019
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Cardiac amyloidosis: A case report and review of literature.

World J Clin Cases 2019 Mar;7(6):742-752

Department of Cardiovascular Sciences, East Carolina Heart Institute, East Carolina University, Greenville, NC 27834, United States.

Background: Cardiac amyloidosis, a disease caused by the precipitation of amyloid proteins in the myocardial extracellular matrix has been historically difficult to diagnose due to lack of specific clinical manifestations and necessity of biopsy to demonstrate amyloid deposition. However, advances in cardiovascular imaging techniques have facilitated earlier recognition of this disease. In addition, while once thought of as incurable, treatment strategies are emerging for cardiac amyloidosis, making early diagnosis essential. Read More

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http://dx.doi.org/10.12998/wjcc.v7.i6.742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448069PMC
March 2019
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"Acing" the Hidden Spade: Review of Diagnosis, Follow-up, Prognosis, and Various Associations of Apical Variant Hypertrophic Cardiomyopathy.

Cureus 2019 Jan 29;11(1):e3979. Epub 2019 Jan 29.

Internal Medicine, University of Central Florida College of Medicine, Orlando, USA.

Apical variant hypertrophic cardiomyopathy (AHCM) is a known entity since its first introduction by Sakamoto and Yamaguchi. However, unlike classical hypertrophic cardiomyopathy (HCM), it is less explored in terms of its associated diagnosis and long-term outcomes. Through this case presentation, we aim to have an in-depth review to help physicians identify and better understand several aspects of AHCM. Read More

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https://www.cureus.com/articles/16639-acing-the-hidden-spade
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http://dx.doi.org/10.7759/cureus.3979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440565PMC
January 2019
3 Reads

Mesalamine-induced Myocarditis in a Young Athlete: Can He Run Again?

Cureus 2019 Jan 29;11(1):e3978. Epub 2019 Jan 29.

Cardiology, State University of New York at Buffalo, Buffalo, USA.

Mesalamine is often used in the treatment of inflammatory bowel disease (IBD). Mesalamine-induced cardiotoxicity has been reported in the literature and is a rare entity. The mechanism of cardiotoxicity remains unclear, however, it is believed to be due to a humoral-mediated hypersensitivity reaction. Read More

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http://dx.doi.org/10.7759/cureus.3978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440563PMC
January 2019
3 Reads

Cardiovascular effects of two adenosine constant rate infusions in anaesthetized dogs.

Vet Anaesth Analg 2019 Feb 8. Epub 2019 Feb 8.

Department of Clinical Diagnostics and Services, Division of Anaesthesiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

Objective: Adenosine induces vasodilatation. The aim of this study was to investigate cardiovascular effects of two adenosine constant rate infusion (CRI) doses in dogs.

Study Design: Experimental, longitudinal repeated measure design. Read More

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http://dx.doi.org/10.1016/j.vaa.2018.12.007DOI Listing
February 2019

Corticosteroid-induced immunodeficiency in a patient with gliomatosis cerebri: Are corticosteroids indicated in all brain tumors?

Clin Neuropathol 2019 Apr 9. Epub 2019 Apr 9.

An elderly male was admitted to the Department of Neurology for slowly progressive dysarthria and right-sided atactic hemiparesis. Magnetic resonance imaging (MRI) revealed a small contrast-enhanced focus of malignant glioma in the left parietal lobe - with the growth pattern of cerebral gliomatosis - involving the whole left cerebral hemisphere, the corpus callosum, and spreading into the right frontal hemisphere. Diagnostic biopsy was deferred until the exclusion of other possible causes of the brain lesion. Read More

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http://dx.doi.org/10.5414/NP301167DOI Listing
April 2019
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Inspiratory collapse of the inferior vena cava and the kissing ventricle sign: markers of poor prognosis in emergency gastrointestinal bleeding.

Emergencias 2019 Abr;31(2):79-85

Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, España.

Objectives: Gastrointestinal bleeding, one of the main reasons for emergency department visits, is associated with significant mortality, complications, and high health care spending. Studies have shown the usefulness of hemodynamic monitoring by ultrasound of the inferior vena cava (IVC), imaging of systolic obstruction of the left ventricle (the kissing sign), changes in cardiac output, or surrogates for cardiac output such as the left ventricular velocity time integral before and after a passive leg raise. There is currently no evidence for applying this approach to evaluating hypovolemia due to gastrointestinal bleeding. Read More

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