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    Myocardial performance index in active and inactive paediatric systemic lupus erythematosus.
    Clin Exp Rheumatol 2017 Feb 3. Epub 2017 Feb 3.
    Department of Paediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University Bangkok, Thailand.
    Objectives: To evaluate cardiac structure and function in paediatric SLE patients without clinical evidence of cardiovascular disease in active and inactive diseases.

    Methods: Patients aged ≤20 years who fulfilled the diagnostic criteria of active SLE underwent transthoracic echocardiography to evaluate cardiac structure and function, and were then followed up echocardiographically every 3-4 months until SLE disease was inactive. Patients with heart failure, myocarditis, pericarditis, endocarditis, coronary artery disease, or abnormal structural heart disease were excluded. Read More

    Diagnosis of neonatal neuroblastoma with postmortem magnetic resonance imaging.
    Radiol Case Rep 2017 Mar 7;12(1):191-195. Epub 2016 Dec 7.
    Department of Diagnostic Radiology, Beaumont Hospital, Royal Oak, MI.
    Postmortem magnetic resonance imaging (MRI) is emerging as a valuable tool to accompany traditional autopsy and has potential for use in cases when traditional autopsy is not possible. This case report will review the use of postmortem MRI with limited tissue sampling to differentiate between metastatic neuroblastoma and hepatoblastoma which could not be clearly differentiated with prenatal ultrasound, prenatal MRI, or emergent postnatal ultrasound. The mother presented to our institution at 27 weeks gestation after an obstetric ultrasound at her obstetrician's office identified a large abdominal mass. Read More

    Systematic review of non-invasive cardiovascular imaging in the diagnosis of constrictive pericarditis.
    Indian Heart J 2017 Jan - Feb;69(1):57-67. Epub 2016 Jun 25.
    Department of Medicine, Division of Cardiology, University of Missouri School of Medicine, Columbia, MO, United States. Electronic address:
    Background: Diagnosis of constrictive pericarditis (CP) can be challenging. It can be nearly impossible to distinguish CP from other causes of right heart failure. Although various imaging modalities help in the diagnosis, no test is definitive. Read More

    Idiopathic dilatation of pulmonary artery: A review.
    Indian Heart J 2017 Jan - Feb;69(1):119-124. Epub 2016 Jul 15.
    Department of Cardiology, Northeastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong 18, Meghalaya, India. Electronic address:
    The diagnosis of idiopathic dilatation of pulmonary artery is challenging because its clinical recognition is difficult and various other causes of dilated pulmonary artery need to be excluded. The clinical findings mimic various common cardiac disorders and both invasive and non-invasive investigations should be done to arrive at the diagnosis. It is a known clinical entity but etiology and pathophysiology are largely unknown. Read More

    Cardiac metastasis from colon cancer effectively treated with 5-fluorouracil, leucovorin, and oxaliplatin (modified FOLFOX6) plus panitumumab: a case report.
    BMC Cancer 2017 Feb 23;17(1):152. Epub 2017 Feb 23.
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
    Background: Cardiac metastasis from colorectal cancer is rare. There is little evidence supporting the effectiveness of chemotherapy, and standard therapy for metastatic cardiac tumors has not been established.

    Case Presentation: A 76-year-old woman presented with a right ventricle tumor that was detected incidentally on screening cardiac ultrasonography. Read More

    Time and resources of peripherally inserted central catheter insertion procedures: a comparison between blind insertion/chest X-ray and a real time tip navigation and confirmation system.
    Clinicoecon Outcomes Res 2017 7;9:115-125. Epub 2017 Feb 7.
    Department of Diagnostic Imaging, Unity Hospital, Rochester, NY, USA.
    Background: The Sherlock 3CG™ Tip Confirmation System (TCS) provides real-time peripherally inserted central catheter (PICC) tip insertion information using passive magnetic navigation and patient cardiac electrical activity. It is an alternative tip confirmation method to fluoroscopy or chest X-ray for PICC tip insertion confirmation in adults. The purpose of this study was to evaluate time and cost of the Sherlock 3CG TCS and blind insertion with chest X-ray tip confirmation (BI/CXR) for PICC insertions. Read More

    Use of Model-based Iterative Reconstruction to Improve Detection of Congenital Cardiovascular Anomalies in Infants Undergoing Free-breathing Computed Tomographic Angiography.
    J Thorac Imaging 2017 Mar;32(2):127-135
    *Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD †Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA.
    Purpose: The aim of the study was to assess the detection of congenital cardiovascular anomalies (congenital heart disease) in neonates and infants using model-based iterative reconstruction (MBIR) algorithm compared with hybrid iterative reconstruction (HIR) and filtered back projection (FBP) reconstructions on axial computed tomography (CT) performed at minimum scanner dose.

    Materials And Methods: Over 1 year, all CT angiographies performed in infants below 3 months of age with congenital heart disease were assessed retrospectively. All were scanned on a 256-slice CT (Brilliance iCT) using single axial rotation at minimum allowable scanner dose (80 kV/10 mAs), with patients free-breathing. Read More

    A low prevalence of non alcoholic fatty liver disease in patients with type 1 diabetes is associated to decreased subclinical cardiovascular disease.
    J Diabetes 2017 Feb 20. Epub 2017 Feb 20.
    Service of Endocrinology and Nutrition, Department of Medicine, Institute of Research and Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, CIBERDEM and CIBERER, Instituto de Salud Carlos III, Spain.
    Background: Non-alcoholic fatty liver disease (NAFLD) has been proposed as an independent cardiovascular risk factor. This study evaluated the prevalence of NAFLD in a cohort of Type 1 Diabetic (T1D) patients and its potential relationship with subclinical cardiovascular disease (CVD).

    Methods: Cross-sectional study in which 100 T1D patients (39. Read More

    Assessing Cardiovascular Risk and Testing in Type 2 Diabetes.
    Curr Cardiol Rep 2017 Mar;19(3):19
    Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, 6565 Fannin St., M.S. A-601, Suite 656, Houston, TX, 77030, USA.
    Purpose Of Review: Type 2 diabetes confers approximately twofold-increased risk for cardiovascular disease. Early risk stratification of these patients may help reduce cardiovascular events. This review discusses the state of the art of risk factors, biomarkers, and subclinical disease parameters potentially useful in cardiovascular risk assessment in type 2 diabetes. Read More

    Synchronous cardiocerebral infarction in the era of endovascular therapy: which to treat first?
    J Thromb Thrombolysis 2017 Feb 20. Epub 2017 Feb 20.
    Division of Neurology, Department of Medicine, National University Health System, 1 E Kent Ridge Road, Singapore, 119228, Singapore.
    A cardiocerebral ischemic attack (CCI) or a concurrent acute ischemic stroke (AIS) and myocardial infarction (AMI) is a severe event with no clear recommendations for ideal management because of the rarity of the scenario. The narrow time window for treatment and complexity of the treatment decision puts immense pressure on the treating physician. We evaluated this challenging situation at our tertiary center. Read More

    Application of confocal laser scanning microscopy for the diagnosis of amyloidosis.
    Virchows Arch 2017 Feb 20. Epub 2017 Feb 20.
    Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Gabelli 61, 35100, Padova, Italy.
    We analysed specificity and sensitivity of confocal laser microscopy (CLSM) on tissue sections for a diagnosis of amyloidosis, in an attempt to reduce technical errors and better standardise pathological diagnosis. We first set up a protocol for the use of CLSM on this type of specimen, using a group of 20 amyloid negative and 20 positive samples. Of all specimens, 2, 4 and 8-μm sections were cut. Read More

    Results of Late Gadolinium Enhancement in Children Affected by Dilated Cardiomyopathy.
    Front Pediatr 2017 6;5:13. Epub 2017 Feb 6.
    Department of Imaging, Bambino Gesù - Children's Hospital IRCCS , Rome , Italy.
    Background: Little is known about the clinical value of late gadolinium enhancement (LGE), in children affected by dilated cardiomyopathy (DCM).

    Materials And Methods: We retrospectively evaluated 15 patients (8 ± 6 years, 6 males) with diagnosis of DCM who underwent cardiac magnetic resonance since 2014. All scans were performed with a 1. Read More

    Ultrasound-guided probe-generated artifacts stimulating ventricular tachycardia: A rare phenomenon.
    Saudi J Anaesth 2017 Jan-Mar;11(1):93-95
    Department of Neuroanaesthesiology, All India Institute of Medical Sciences, New Delhi, India.
    Electrocardiographic (ECG) artifacts may arise due to interference, faulty earthing, and current leakages in biomedical equipment which might create clinical dilemmas in the perioperative settings. Piezoelectric signals generated by ultrasonography probe are another uncommon source which might be sensed by the ECG electrodes and produce tracings similar to pathological arrhythmias triggering false alarms and avoidable therapies. Anesthesiologists should be familiar with these uncommon sources which might produce these artifacts and they should be identified swiftly. Read More

    Ultrasonography-guided pulsed radiofrequency of sciatic nerve for the treatment of complex regional pain syndrome Type II.
    Saudi J Anaesth 2017 Jan-Mar;11(1):83-85
    Department of Anesthesiology and Pain Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea.
    Although the major mechanism of complex regional pain syndrome (CRPS) involves dysfunctional central or sympathetic nervous system activation, the peripheral nervous system also contributes significantly to its clinical manifestations. Pulsed radiofrequency (PRF) is a recently developed treatment option for neuropathic pain syndromes. Here, we report a case of CRPS Type II after a femur fracture and sciatic nerve injury, in which the pain was treated successfully with ultrasonography-guided selective sciatic nerve PRF application. Read More

    Potassium Chloride Infusion as the Cause of Altered Bio Distribution of (18)F-Fluorodeoxyglucose on Whole-Body Positron Emission Tomography-Computed Tomography Scan.
    World J Nucl Med 2017 Jan-Mar;16(1):81-83
    Department of Nuclear Medicine and PET-CT, P.D. Hinduja National Hospital and MRC, Mumbai, Maharashtra, India.
    (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography is a standard diagnostic imaging tool in many types of cancer. Its physiological in vivo distribution includes the brain, liver, heart, kidneys, and urinary tract at 1 h after tracer injection. Skeletal muscle is known to show variable amounts of (18)F-FDG uptake because it has a relatively high-glucose metabolism. Read More

    [Clinical value of the evolution of left ventricular global strain in anterior myocardial infarction patients treated with emergency percutaneous coronary intervention].
    Zhong Nan Da Xue Xue Bao Yi Xue Ban 2017 Jan;42(1):41-48
    Department of Ultrasonography, Second Xiangya Hospital,
Central South University, Changsha 410011, China.
    Objective: To investigate the evolution of left ventricular global strain in anterior myocardial infarction patients treated with emergency percutaneous coronary intervention (PCI).
 Methods: A total of 54 patients with PCI were enrolled as a PCI group. Forty healthy subjects were enrolled as a control group. Read More

    Quantification of myocardial oxygenation in heart failure using blood-oxygen-level-dependent T2* magnetic resonance imaging: Comparison with cardiopulmonary exercise test.
    Magn Reson Imaging 2017 Feb 16. Epub 2017 Feb 16.
    Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
    Purpose: Quantification of myocardial oxygenation (MO) in heart failure (HF) has been less than satisfactory. This has necessitated the use of invasive techniques to measure MO directly or to determine the oxygen demand during exercise using the cardiopulmonary exercise (CPX) test. We propose a new quantification method for MO using blood-oxygen-level-dependent (BOLD) myocardial T2* magnetic resonance imaging (M-T2* MRI), and investigate its correlation with CPX results. Read More

    Diagnostic and Prognostic Value of Lead aVR During Exercise Testing in Patients Suspected of Having Myocardial Ischemia.
    Am J Cardiol 2017 Jan 5. Epub 2017 Jan 5.
    Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:
    We aimed to assess the diagnostic and prognostic value of ST-segment deviation in aVR, a lead often ignored in clinical practice, during exercise testing and to compare it to the most widely used criterion of ST-segment depression in V5. We enrolled 1,596 patients with suspected myocardial ischemia referred for nuclear perfusion imaging undergoing bicycle stress testing. ST-segment amplitudes in leads aVR and V5 were automatically measured. Read More

    Why Edema Is a Matter of the Heart.
    Circ Cardiovasc Imaging 2017 Feb;10(2)
    From the Departments of Medicine and Diagnostic Radiology, McGill University, Montréal, Québec, Canada; Department of Medicine, Heidelberg University, Germany; Département de radiologie, Université de Montréal, Montréal, Québec, Canada; and Departments of Cardiac Sciences and Radiology, University of Calgary, Canada.

    Point-of-care ultrasonography for evaluation of acute dyspnea in the emergency department.
    Chest 2017 Feb 14. Epub 2017 Feb 14.
    Emergency Department, Careggi University Hospital, Florence, Italy.
    Background: Acute dyspnea is a common symptom in the emergency department (ED). Standard approach to dyspnea often relies on radiologic and laboratoristic results, causing excessive delay before adequate therapy is started; an integrated point-of-care ultrasonography (PoCUS) approach can shorten the time needed to formulate a diagnosis maintaining an acceptable safety profile.

    Methods: Consecutive adult patients presenting with dyspnea and admitted after ED evaluation were prospectively enrolled. Read More

    Transthoracic Echocardiography: Pitfalls and Limitations as Delineated at Cardiac CT and MR Imaging.
    Radiographics 2017 Feb 17:160105. Epub 2017 Feb 17.
    From the Department of Diagnostic Imaging, Kaiser Permanente Los Angeles Medical Center, 1505 N Edgemont Ave, Basement, Los Angeles, CA 90027.
    Transthoracic echocardiography ( TTE transthoracic echocardiography ) is a critical tool in the field of clinical cardiology. It often serves as one of the first-line imaging modalities in the evaluation of cardiac disease owing to its low cost, portability, widespread availability, lack of ionizing radiation, and ability to evaluate both anatomy and function of the heart. Consequently, a large majority of patients undergoing a cardiac computed tomography (CT) or magnetic resonance (MR) imaging examination will have a TTE transthoracic echocardiography available for review. Read More

    Arterial-ventricular coupling and parameters of vascular stiffness in hypertensive patients: Role of gender.
    JRSM Cardiovasc Dis 2017 Jan-Dec;6:2048004017692277. Epub 2017 Feb 1.
    Department of Clinical and experimental Medicine, University of Pisa, Italy.
    Objective: Non-invasive estimation of arterial-ventricular coupling has been extensively used for the evaluation of cardiovascular performance, however, a relative small amount of data is available regarding arterial-ventricular coupling and its components in hypertension. The present study was designed to investigate the relationship between left ventricular elastance, arterial elastance, parameters of vascular stiffness and the influence of gender in a population of hypertensive individuals.

    Methods: In 102 patients, trans-thoracic cardiac ultrasound, parameters of aortic stiffness (carotid-femoral pulse wave velocity) and wave reflection (augmentation index) were recorded. Read More

    Acetylcholine versus cold pressor testing for evaluation of coronary endothelial function.
    PLoS One 2017 16;12(2):e0172538. Epub 2017 Feb 16.
    Cedars-Sinai Heart Institute, Los Angeles, California, United States of America.
    Background: Assessment of coronary endothelial function with intracoronary acetylcholine (IC-Ach) provides diagnostic and prognostic data in patients with suspected coronary microvascular dysfunction (CMD), but is often not feasible due in part to the time and expertise needed for pharmacologic mixing. Cold pressor testing (CPT) is a simple and safe stimulus useful for either invasive or non-invasive endothelial function testing and myocardial perfusion imaging but has not been specifically evaluated among symptomatic women with signs of ischemic heart disease (IHD) who have no obstructive coronary artery disease (CAD).

    Methods: 163 women with signs and symptoms of IHD and no obstructive CAD from the NHLBI- Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study underwent coronary reactivity testing with a Doppler flow wire (FloWire® Volcano, San Diego, CA) in the proximal left anterior descending artery. Read More

    Imaging cardiac SCN5A using the novel F-18 radiotracer radiocaine.
    Sci Rep 2017 Feb 16;7:42136. Epub 2017 Feb 16.
    Harvard Medical School, Massachusetts General Hospital, Martinos Center for Biomedical Imaging, 149 13th Street, 02129 Charlestown, MA, USA.
    The key function of the heart, a well-orchestrated series of contractions, is controlled by cardiac action potentials. These action potentials are initiated and propagated by a single isoform of voltage gated sodium channels - SCN5A. However, linking changes in SCN5A expression levels to human disease in vivo has not yet been possible. Read More

    Increased maximum common carotid intima-media thickness is associated with smoking and hypertension in Tochigi Prefecture residents.
    J Med Ultrason (2001) 2017 Feb 15. Epub 2017 Feb 15.
    Stroke Division, Department of Neurology, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsuga-gun, Tochigi, 322-0293, Japan.
    Objective: We investigated maximum intima-media thickness of the common carotid artery (IMT-Cmax) in residents of Tochigi Prefecture, who have been reported to have high stroke mortality.

    Method: Our study included 840 individuals. All participants underwent carotid ultrasonography and answered a questionnaire during participation in a health festival in Tochigi Prefecture. Read More

    A Recurrent Case of Pentalogy of Cantrell: A Rare Case with Sonological Findings and Review of Literature.
    Pol J Radiol 2017 18;82:28-31. Epub 2017 Jan 18.
    Department of Radiodiagnosis, Christian Medical College, Vellore, India.
    Background: Pentalogy of Cantrell (POC) is an extremely rare and complex congenital anomaly. Ultrasound is a valuable, safe, nonionizing, cost effective, widely available, and easily reproducible imaging tool and is indispensible in the diagnosis of POC. Despite the rarity of POC, it is imperative for a radiologist to be aware of its wide spectrum of presentation on ultrasound in first trimester of gestation. Read More

    Variability of radiation doses of cardiac diagnostic imaging tests: the RADIO-EVINCI study (RADIationdOse subproject of the EVINCI study).
    BMC Cardiovasc Disord 2017 Feb 16;17(1):63. Epub 2017 Feb 16.
    Fondazione Toscana G. Monasterio, via Moruzzi, 1, Pisa, Italy.
    Background: Patients with coronary artery disease can accumulate significant radiation dose through repeated exposures to coronary computed tomographic angiography, myocardial perfusion imaging with single photon emission computed tomography or positron emission tomography, and to invasive coronary angiography. Aim of the study was to audit radiation doses of coronary computed tomographic angiography, single photon emission computed tomography, positron emission tomography and invasive coronary angiography in patients enrolled in the prospective, randomized, multi-centre European study-EVINCI (Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease).

    Methods: We reviewed 1070 tests (476 coronary computed tomographic angiographies, 85 positron emission tomographies, 310 single photon emission computed tomographies, 199 invasive coronary angiographies) performed in 476 patients (mean age 60 ± 9 years, 60% males) enrolled in 12 centers of the EVINCI. Read More

    MR Imaging in Patients with Cardiac Pacemakers and Implantable Cardioverter Defibrillators.
    Rofo 2017 Feb 15. Epub 2017 Feb 15.
    Klinik für Innere Medizin/Kardiologie KMG-Kliniken Güstrow, Deutschland - Department of Internal Medicine/Kardiology, KMG Hospital Guestrow, Germany.
    This joint consensus paper of the German Roentgen Society and the German Cardiac Society provides physical and electrophysiological background information and specific recommendations for the procedural management of patients with cardiac pacemakers (PM) and implantable cardioverter defibrillators (ICD) undergoing magnetic resonance (MR) imaging. The paper outlines the responsibilities of radiologists and cardiologists regarding patient education, indications, and monitoring with modification of MR sequences and PM/ICD reprogramming strategies being discussed in particular. The aim is to optimize patient safety and to improve legal clarity in order to facilitate the access of SM/ICD patients to MR imaging. Read More

    Diagnostic Performance of T1 and T2 Mapping to Detect Intramyocardial Hemorrhage in Reperfused ST-Segment Elevation Myocardial Infarction (STEMI) Patients.
    J Magn Reson Imaging 2017 Feb 15. Epub 2017 Feb 15.
    Hatter Cardiovascular Institute, Institute of Cardiovascular Science University College London, UK.
    Purpose: To investigate the performance of T1 and T2 mapping to detect intramyocardial hemorrhage (IMH) in ST-segment elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PPCI).

    Materials And Methods: Fifty STEMI patients were prospectively recruited between August 2013 and July 2014 following informed consent. Forty-eight patients completed a 1. Read More

    Acute "Pseudoischemic" ECG Abnormalities after Right Pneumonectomy.
    Case Rep Surg 2017 18;2017:7872535. Epub 2017 Jan 18.
    Clinic for Pulmonary Diseases, Clinical Center of Serbia, Belgrade, Serbia.
    New onset of electrocardiographic (ECG) abnormalities can occur after lung surgery due to the changes in the position of structures and organs in the chest cavity. The most common heart rhythm disorder is atrial fibrillation. So-called "pseudoischemic" ECG changes that mimic classic ECG signs of acute myocardial ischemia are also often noticed. Read More

    Diagnostic Approach to Myocarditis Mimicking Myocardial Infarction at Initial Presentation.
    Cardiol Res 2016 Dec 31;7(6):209-213. Epub 2016 Dec 31.
    St John Hospital and Medical Center, Wayne State University School of Medicine, Detroit, MI, USA; University of Alabama at Birmingham (UAB) Medical Center, Birmingham, Alabama, AL, USA; Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA.
    We present a case of a 35-year-old male patient with a 12-hour history of sudden-onset, crushing chest pain and associated complaints of profuse diaphoresis, nausea and vomiting. The patient was transferred to our institution from an outside hospital for evaluation and possible emergent catheterization. Left heart catheterization was conclusive for normal coronary arteries and a ventriculogram revealed a left ventricular ejection fraction of approximately 45%. Read More

    Pulse Pressure and Upstroke Time Are Useful Parameters for the Diagnosis of Peripheral Artery Disease in Patients With Normal Ankle Brachial Index.
    Cardiol Res 2016 Oct 3;7(5):161-166. Epub 2016 Nov 3.
    Department of Cardiovascular Medicine, Toho University Faculty of Medicine, Tokyo, Japan.
    Background: Some peripheral artery disease (PAD) patients have normal ankle brachial index (ABI) (0.9 - 1.4), although ABI is a useful parameter for the diagnosis of PAD. Read More

    Cor triatriatum sinistrum: presentation of syncope and atrial tachycardia.
    BMJ Case Rep 2017 Feb 14;2017. Epub 2017 Feb 14.
    Papworth Hospital NHS Foundation Trust, Cambridge, UK.
    We present a rather unusual cause for syncope associated with atrial tachycardia. A man aged 39 years presented with an episode of syncope and narrow complex tachycardia. Further investigations, including transoesophageal echocardiography, identified cor triatriatum sinistrum (CTS), a rare congenital abnormality characterised by the atrium being divided by a fibrous membrane. Read More

    A Case Report of Onyx Pulmonary Arterial Embolism Contributing to Hypoxemia During Awake Craniotomy for Arteriovenous Malformation Resection.
    A A Case Rep 2017 Feb;8(4):86-88
    From the Departments of *Anesthesiology, †Neurology, and ‡Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill.
    A healthy 26-year-old man with cerebral arteriovenous malformation underwent staged endovascular embolization with Onyx followed by awake craniotomy for resection. The perioperative course was complicated by tachycardia and severe intraoperative hypoxemia requiring significant oxygen supplementation. Postoperative chest computed tomography (CT) revealed hyperattenuating Onyx embolization material within the pulmonary vasculature, and an electrocardiogram indicated possible right heart strain, supporting clinically significant embolism. Read More

    Preterm arteries in childhood: dimensions, intima-media thickness, and elasticity of the aorta, coronaries, and carotids in 6-y-old children born extremely preterm.
    Pediatr Res 2017 Feb 27;81(2):299-306. Epub 2016 Oct 27.
    Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
    Background: Preterm birth increases risk for adult cardiovascular disease. We hypothesized that arteries in 6-y-old children born preterm are narrower, with thicker intima-media and stiffer than in peers born at term.

    Methods: Children born extremely preterm (EXP, n = 176, birthweights: 348-1,161 g) and at term (CTRL, n = 174, birthweights: 2,430-4,315 g) were included. Read More

    Imaging of the Vasa Nervorum Using Contrast-Enhanced Ultrasound.
    J Neuroimaging 2017 Feb 14. Epub 2017 Feb 14.
    Zeenat Qureshi Stroke Institute, St. Cloud, MN.
    Introduction: We describe the use of intravenous contrast-enhanced ultrasonography to study vasa nervorum using contrast-enhanced ultrasound.

    Methods: We imaged the median, femoral, or sciatic nerves in 4 patients in longitudinal plane using high-resolution ultrasound after intravenous bolus of activated Perflutren lipid microspheres. The images were acquired as photopic images (in brown color) in real time using 2-dimensional B-Flow mode scan within a selected region of interest. Read More

    [(68)Ga]NOTA-Galactosyl Human Serum Albumin: a Tracer for Liver Function Imaging with Improved Stability.
    Mol Imaging Biol 2017 Feb 13. Epub 2017 Feb 13.
    Department of Nuclear Medicine, Medical University of Innsbruck, Anichstr. 35, 6020, Innsbruck, Austria.
    Purpose: Non-invasive techniques allowing quantitative determination of the functional liver mass are of great interest for patient management in a variety of clinical settings. Recently, we presented [(68)Ga]DTPA-GSA to target the hepatic asialoglycoprotein receptor for this purpose. Here, we introduce [(68)Ga]NOTA-GSA to improve metabolic stability of the radiopharmaceutical and compare the imaging properties with [(68)Ga]DTPA-GSA. Read More

    Intermittent auscultation (IA) of fetal heart rate in labour for fetal well-being.
    Cochrane Database Syst Rev 2017 Feb 13;2:CD008680. Epub 2017 Feb 13.
    Liggins Institute, The University of Auckland, Park Road, Grafton, Auckland, New Zealand, 1142.
    Background: The goal of fetal monitoring in labour is the early detection of a hypoxic baby. There are a variety of tools and methods available for intermittent auscultation (IA) of the fetal heart rate (FHR). Low- and middle-income countries usually have only access to a Pinard/Laënnec or the use of a hand-held Doppler device. Read More

    Self-inflicted Cardiac Injury with Nail Gun Without Hemodynamic Compromise: A Case Report.
    Cureus 2017 Jan 10;9(1):e971. Epub 2017 Jan 10.
    College of Medicine, University of Central Florida ; Florida Hospital-Orlando.
    Pneumatically powered nail guns have been used in construction since 1959. Penetrating injuries to the heart with nail guns have a wide range of presentations from asymptomatic to cardiac tamponade and exsanguination. Mortality related to cardiac nail gun injuries is similar to knife injuries, estimated at 25%. Read More

    Myocardial perfusion imaging with PET.
    Int J Cardiovasc Imaging 2017 Feb 10. Epub 2017 Feb 10.
    Department of Cardiology, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
    Noninvasive assessment of coronary artery disease remains a challenging task, with a large armamentarium of diagnostic modalities. Myocardial perfusion imaging (MPI) is widely used for this purpose whereby cardiac positron emission tomography (PET) is considered the gold standard. Next to relative radiotracer distribution, PET allows for measurement of absolute myocardial blood flow. Read More

    Contrast echocardiography for detection of myocardial perfusion abnormalities : A clinical perspective.
    Herz 2017 Feb 10. Epub 2017 Feb 10.
    Department of Echocardiography, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK.
    Myocardial contrast echocardiography (MCE) is a well-established imaging technique in the assessment of patients with known or suspected coronary artery disease. The use of ultrasound contrast agents has optimized the evaluation of left ventricular function and, moreover, permits simultaneous assessment of the myocardial perfusion. This technique utilizes microbubbles that remain in the intravascular space and the contrast intensity reflects the concentration of the microbubbles in the myocardium. Read More

    Transcranial Doppler-determined change in posterior cerebral artery blood flow velocity does not reflect vertebral artery blood flow during exercise.
    Am J Physiol Heart Circ Physiol 2017 Feb 10:ajpheart.00676.2016. Epub 2017 Feb 10.
    Toyo University
    We examined whether a change in posterior cerebral artery flow velocity (PCAv) reflected the posterior cerebral blood flow, in healthy subjects, during both static and dynamic exercise. PCAv and vertebral artery (VA) blood flow, as an index of posterior blood flow, were continuously measured during an exercise trial, using transcranial Doppler (TCD) ultrasonography and Doppler ultrasound, respectively. Static handgrip exercise significantly increased both PCAv and VA blood flow. Read More

    Cardiac diagnostic work-up for atrial fibrillation after transient ischaemic attacks in England and Wales: results from a cross-sectional survey.
    BMJ Open 2016 Nov 10;6(11):e012714. Epub 2016 Nov 10.
    Department of Stroke Medicine, Imperial College London, London, UK.
    Objectives: Transient ischaemic attacks (TIAs) are an important precursor of stroke. Atrial fibrillation (AF) is among the most dangerous aetiologies shared between TIAs and strokes. Detection of AF after TIAs is essential for the initiation of oral anticoagulants. Read More

    [Analysis of the cause of pregnancy failure with combined MLPA assay for subtelomeric regions and ultrasonography].
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2017 Feb;34(1):81-84
    Prenatal Diagnostic Center, Dongguan Mother and Child Healthcare Hospital, Dongguan, Guangdong 523000, China.
    Objective: To explore the value of multiplex ligation-dependent probe amplification (MLPA) for the detection of chromosome abnormalities in miscarriage tissues, and to correlate the result with ultrasound findings.

    Methods: A total of 421 cases of spontaneous abortions and fetal deaths were detected with the MLPA method.

    Results: Among the 421 samples, 232 (55. Read More

    [Combined G-banded karyotyping and multiplex ligation-dependent probe amplification for the detection of chromosomal abnormalities in fetuses with congenital heart defects].
    Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2017 Feb;34(1):1-5
    Center for Prenatal Diagnosis, Shenzhen Maternity and Child Healthcare Hospital Affiliated to Southern Medical University, Shenzhen, Guangdong 518017, China.
    Objective: To assess the value of G-banded karyotyping in combination with multiplex ligation-dependent probe amplification (MLPA) as a tool for the detection of chromosomal abnormalities in fetuses with congenital heart defects.

    Methods: The combined method was used to analyze 104 fetuses with heart malformations identified by ultrasonography. Abnormal findings were confirmed with chromosomal microarray analysis (CMA). Read More

    The diagnostic accuracy of myocardial perfusion scintigraphy in athletes with abnormal exercise test results.
    Eur J Prev Cardiol 2017 Jan 1:2047487317693135. Epub 2017 Jan 1.
    1 Department of Cardiology, Máxima Medical Center Veldhoven, The Netherlands.
    Background Previous studies revealed a relatively high prevalence of electrocardiographic findings indicative for myocardial ischemia in asymptomatic athletes undergoing pre-participation screening. Myocardial perfusion scintigraphy is generally considered a valuable diagnostic and prognostic modality and often used for further diagnostic evaluation in these subjects. However, data on the diagnostic accuracy of myocardial perfusion scintigraphy in athletes are scarce. Read More

    Multimodality molecular imaging in cardiac regenerative therapy.
    J Nucl Cardiol 2017 Feb 9. Epub 2017 Feb 9.
    Division of Cardiovascular Medicine, Department of Medicine, Stanford University, 300 Pasteur Drive, Stanford, CA, 94305, USA.
    Stem cell therapy holds great promise for the repair and regeneration of damaged myocardium. Disappointing results from recent large-scale randomized trials using adult stem cells, however, have led some to question the efficacy of this new therapeutic. Because most clinical stem cell trials have not incorporated molecular imaging to track cell fate, it may be premature to abandon this approach. Read More

    (18)F-FDG-PET/CT Angiography for the Diagnosis of Infective Endocarditis.
    Curr Cardiol Rep 2017 Feb;19(2):15
    Department of Nuclear Medicine, Hospital Universitari Vall d'Hebron, Passeig Vall d'Hebron 119-129, 08035, Barcelona, Spain.
    Purpose Of Review: This article reviews the current imaging role of (18)F-fluordeoxyglucose positron emission computed tomography ((18)F-FDG-PET/CT) combined with cardiac CT angiography (CTA) in infective endocarditis and discusses the strengths and limitations of this technique.

    Recent Findings: The diagnosis of infective endocarditis affecting prosthetic valves and intracardiac devices is challenging because echocardiography and, therefore, the modified Duke criteria have well-recognized limitations in this clinical scenario. The high sensitivity of (18)F-FDG-PET/CT for the detection of infection associated with the accurate definition of structural damage by gated cardiac CTA in a combined technique (PET/CTA) has provided a significant increase in diagnostic sensitivity for the detection of IE. Read More

    Cardiac and respiratory motion correction for simultaneous cardiac PET-MR.
    J Nucl Med 2017 Feb 9. Epub 2017 Feb 9.
    King's College London, Division of Imaging Sciences and Biomedical Engineering, United Kingdom.
    Cardiac Positron Emission Tomography (PET) is a versatile imaging technique providing important diagnostic information about ischemic heart diseases. Respiratory and cardiac motion of the heart can strongly impair image quality and therefore diagnostic accuracy of cardiac PET scans. The aim of this study is to investigate a new cardiac PET-Magnetic Resonance (MR) approach providing respiratory and cardiac motion-compensated MR and PET images in less than five minutes. Read More

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