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J Orthop Surg (Hong Kong) 2022 May-Aug;30(2):10225536221109914

Department of Orthopedic Surgery, Uijeongbu Eulji Medical Center, 587171Eulji University School of Medicine, Uijeongbu, Korea.

Purpose: The aim of this study was to suggest treatment guidline for primary elbow OA with ulnar nerve neuropathy or high-grade stiffness by evaluating the effect of ulnar nerve decompression on the outcome of osteocapsular arthroplasty.

Methods: A total of 30 patients who underwent primary osteocapsular arthroplasty for elbow OA were retrospectively reviewed. The surgical outcomes were evaluated for pain score (visual analog scale; VAS), range of motion (ROM), and Mayo Elbow Performance Score (MEPS). Read More

Cureus 2022 May 21;14(5):e25179. Epub 2022 May 21.

Department of Neuroscience, University of the East Ramon Magsaysay Memorial Medical Center, Quezon City, PHL.

Multifocal motor neuropathy (MMN) is a progressive, multifocal weakness, which typically begins and predominates in the upper extremities with the absence of a sensory deficit and a hallmark electrophysiologic finding of conduction block. We describe a case of an adult male with MMN who developed both cranial nerve involvement and vocal cord paralysis. The patient presented with left shoulder weakness without sensory loss followed by hoarseness of voice and later developed tongue deviation and wasting of the left sternocleidomastoid and left trapezius muscle. Read More

Diagnostics (Basel) 2022 May 28;12(6). Epub 2022 May 28.

Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791 Bochum, Germany.

Echogenicity of peripheral nerves in high-resolution ultrasound (HRUS) provides insight into the structural damage of peripheral nerves in various polyneuropathies. The aim of this study was to compare nerve echogenicity in different primarily axonal or demyelinating polyneuropathies to examine the significance of this parameter. Performing semi-automated echogenicity analysis and applying Image J, we retrospectively used HRUS images of 19 patients with critical illness polyneuropathy (CIP), and 27 patients with chemotherapy-induced polyneuropathy (CIN) and compared them to 20 patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Read More

Strategies Trauma Limb Reconstr 2022 Jan-Apr;17(1):7-13

Department of Orthopaedic Surgery and Musculoskeletal Trauma, University Hospital of Larissa, Larissa, Greece.

Purpose: This is a retrospective cohort study of type C distal humeral fractures (AO classification system) aimed at evaluating the effectiveness of current operative treatment options.

Materials And Methods: Thirty-seven patients with type C distal humeral fractures, treated operatively from January 2002 to September 2016, were retrospectively studied. Thirty-two were eligible for inclusion. Read More

Spinal Cord Ser Cases 2022 Jun 22;8(1):61. Epub 2022 Jun 22.

Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Introduction: Entrapment neuropathies, typically carpal tunnel syndrome and ulnar neuropathy, frequently occur in patients with spinal cord injury (SCI). Upper limb impairments due to entrapment neuropathy can be particularly debilitating in this population. Anterior interosseous nerve (AIN) neuropathy has not been previously described in the SCI population. Read More

Neurol Sci 2022 Jun 20. Epub 2022 Jun 20.

Department of Neuroscience, Rehabilitation Unit, University of Padova, Padua, Italy.

Plast Reconstr Surg Glob Open 2022 Jun 14;10(6):e4378. Epub 2022 Jun 14.

Charleston Area Medical Center, Charleston, W.Va.

Various techniques exist for treating recurrent carpal and ulnar tunnel syndrome, but AxoGuard nerve wrap has shown promising results for treatment of compression neuropathies when used in conjunction with neurolysis and tenosynovectomy. Prior results demonstrate no safety concerns, and there have not been any reported cases of infection, persistent inflammation, or recurrent perineural fibrosis. A 41-year-old, right-hand-dominant woman experienced repeated bouts of carpal and ulnar tunnel syndromes, which were treated with a small intestine submucosa matrix wrap around the median and ulnar nerves in the wrist. Read More

J Plast Reconstr Aesthet Surg 2022 Apr 28. Epub 2022 Apr 28.

Department of Neurosurgery, Haaglanden Medical Center, The Hague, the Netherlands.

Background: Submuscular transposition (SMT) of the ulnar nerve is frequently performed as secondary procedure in patients with persistent or recurrent cubital tunnel syndrome (CuTS) despite previous surgery. Good results have been reported for this surgical strategy, but mainly in small retrospective case series. The goal of the present study is therefore to analyze the results prospectively using a patient-reported outcome measure (PROM): patient-rated ulnar nerve evaluation (PRUNE). Read More

Arch Phys Med Rehabil 2022 Jun 8. Epub 2022 Jun 8.

University of Health Sciences, Ankara Training and Research Hospital, Department of Physical Medicine and Rehabilitation, Ankara, Turkey.

Objective: To compare perineural dextrose injection efficacy in the treatment of ulnar neuropathy at the elbow with a control group.

Design: Prospective, double-blind, randomized, control study.

Settings: Training and Research Hospital Participants: The study was completed with 40 patients with ulnar neuropathy at the elbow Intervention: Normal saline (0. Read More

Handchir Mikrochir Plast Chir 2022 Jun 10;54(3):253-262. Epub 2022 Jun 10.

University of Western Ontario Roth|McFarlane Hand and Upper Limb Center.

Cubital tunnel syndrome is one of the most common upper extremity nerve entrapment conditions. Clinical examination and electrodiagnostic studies assist in the diagnosis. Mild cases can be successfully treated conservatively, aiming to reduce traction and compression on the nerve. Read More

J Clin Med 2022 May 27;11(11). Epub 2022 May 27.

Center for Mitochondrial Research and Medicine, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833, Taiwan.

Background: Growth differentiation factor (GDF15) is a superfamily of transforming growth factor-beta which has been suggested to be correlated with various pathological conditions. The current study aimed to investigate the predicted role of circulating GDF15 in diabetic metabolism characteristics and diabetic neuropathy.

Methods: 241 diabetic patients and 42 non-diabetic subjects were included to participate in the study. Read More

Ultrasound Med Biol 2022 Jun 3. Epub 2022 Jun 3.

Department of Neurology, Rostock University, Rostock, Germany.

Because of the insidious character and variations in presenting symptoms, Charcot-Marie-Tooth (CMT) disease is challenging to diagnose in children. Diagnosis is based on clinical and nerve conduction studies, as well as genetic examination. Therefore, competent nerve imaging techniques and non-invasive alternatives to nerve conduction studies are a necessity, especially in children. Read More

J Plast Reconstr Aesthet Surg 2022 Apr 27. Epub 2022 Apr 27.

Department of Orthopaedic Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea. Electronic address:

Guyon canal (GC) syndrome is a rare peripheral neuropathy involving the distal part of the ulnar nerve. Several causes are associated with GC syndrome, including anatomic variations, space-occupying tumors, and trauma. Because of disease rarity, the only reported studies of GC syndrome are case series with small sample size. Read More

Bull Hosp Jt Dis (2013) 2022 Jun;80(2):209-212

Background: Cubital tunnel syndrome and the resulting loss of hand dexterity and strength may necessitate surgical management. Studies have demonstrated no difference in outcome between surgical techniques. In an attempt to leave more ulnar nerves in situ while providing for stability within the cubital tunnel, we suggest a surgical treatment approach. Read More

Bull Hosp Jt Dis (2013) 2022 Jun;80(2):200-208

Introduction: Carpal tunnel syndrome and ulnar nerve compression at the elbow (e.g., cubital tunnel syndrome) are the most common upper extremity compressive neuropa- thies treated by hand surgeons. Read More

Skeletal Radiol 2022 May 30. Epub 2022 May 30.

Department of Radiology, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.

Background And Purpose: Fascicular targeting of longitudinal intrafascicular electrode (FAST-LIFE) interface enables hand dexterity with exogenous electrical microstimulation for sensory restoration, custom neural recording hardware, and deep learning-based artificial intelligence for motor intent decoding. The purpose of this technical report from a prospective pilot study was to illustrate magnetic resonance neurography (MRN) mapping of hand and nerve anatomy in amputees and incremental value of MRN over electrophysiology findings in pre-surgical planning of FAST-LIFE interface (robotic hand) patients.

Materials And Methods: After obtaining informed consent, patients with upper extremity amputations underwent pre-operative 3-T MRN, X-rays, and electrophysiology. Read More

Plast Reconstr Surg Glob Open 2022 May 24;10(5):e4352. Epub 2022 May 24.

Department of Orthopaedic Surgery, Tulane University School of Medicine, New Orleans, La.

Hamate fractures are an infrequent injury and are often missed or have a delayed diagnosis with potential for significant patient morbidity. There is a relative paucity in the literature involving large population studies of hamate fractures and subsequent complications. Gaining a better understanding of complications associated with nonoperative management will help guide the decision for operative intervention. Read More

Muscle Nerve 2022 May 26. Epub 2022 May 26.

Department of Neurology, Kawasaki Medical School, Okayama, Japan.

Introduction/aims: Posterior antebrachial cutaneous (PABC) nerve conduction studies could be useful for distinguishing PABC neuropathy from C7 radiculopathy. In the conventional method using an antidromic method, the sensory nerve action potential (SNAP) is sometimes followed by a large volume-conducted motor potential. In this report we describe a reliable nerve conduction study using an orthodromic method for recording SNAPs of the PABC nerve. Read More

Semin Musculoskelet Radiol 2022 Apr 24;26(2):123-139. Epub 2022 May 24.

Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Neuropathies of the elbow represent a spectrum of disorders that involve more frequently the ulnar, radial, and median nerves. Reported multiple pathogenic factors include mechanical compression, trauma, inflammatory conditions, infections, as well as tumor-like and neoplastic processes. A thorough understanding of the anatomy of these peripheral nerves is crucial because clinical symptoms and imaging findings depend on which components of the affected nerve are involved. Read More

J Clin Neuromuscul Dis 2022 Jun;23(4):175-182

Division of Neurology, Kobe University Graduate School of Medicine, Kobe, Japan.

Objectives: To evaluate the utility of repetitive nerve stimulation test (RNS) for differentiating multifocal motor neuropathy (MMN) and progressive muscular atrophy (PMA).

Methods: We retrospectively enrolled 20 patients with MMN or PMA. We extracted the results of the initial 3-Hz RNS in the ulnar and accessory nerves and compared the percentage and frequency of abnormal decremental responses between both groups. Read More

J Hand Surg Glob Online 2022 May 10;4(3):172-175. Epub 2021 Dec 10.

Department of Orthopaedic Surgery, Yodogawa Christian Hospital, Kunijima, Higashiyodogawa-ku, Osaka, Japan.

Leprosy is a chronic infection in humans that mainly affects the peripheral nerves and skin. Paraffin filling has been previously used for muscle atrophy treatment. However, the formation of paraffin granulomas (paraffinomas) can occur over the long term. Read More

Neurologia (Engl Ed) 2022 May 24;37(4):243-249. Epub 2021 Apr 24.

Servicio de Neurofisiología Clínica, Complejo Hospitalario de Navarra, Pamplona, Spain.

Introduction: Hereditary neuropathy with liability to pressure palsy (HNPP) is an autosomal dominant disorder, typically presenting with recurrent episodes of mononeuropathy in nerves susceptible to compression, with similar neurophysiological characteristics. However, other clinical and neurophysiological presentations have been reported.

Methods: We retrospectively analysed the clinical and neurophysiological characteristics of 20 patients with genetically confirmed HNPP. Read More

Int J Surg Case Rep 2022 Jun 11;95:107182. Epub 2022 May 11.

Department of Orthopaedics, University Medical Center Ho Chi Minh City, 201 Nguyen Chi Thanh Street, District 5, Ho Chi Minh City, Viet Nam. Electronic address:

Introduction: Compression of the ulnar nerve at the wrist is a rare condition. Clinical presentations of ulnar nerve compression at the wrist and hand can vary widely due to the complex anatomic course of ulnar nerve at the wrist. Lipoma is a common benign soft tissue tumor and rarely causes neuropathy. Read More

Cureus 2022 Apr 6;14(4):e23892. Epub 2022 Apr 6.

Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.

In Bangladesh, tuberculosis and leprosy are endemic mycobacterial diseases; however, co-infection is rarely seen. Our patient had a high-grade fever, symmetrical polyarthritis, polymorphous erythematous lesions, widespread lymphadenopathy, peripheral neuropathy, bilaterally thickened ulnar nerves, and claw hands. A lymph node biopsy revealed tuberculosis having acid-fast bacilli with caseating epithelioid histiocytic granuloma. Read More

Case Rep Orthop 2022 29;2022:6041577. Epub 2022 Apr 29.

Department of Orthopaedics and Traumatology, Venizeleio and Pananio General Hospital of Heraklion Crete, Greece.

Introduction: Neglected distal humerus fractures are rare injuries, which the orthopaedic surgeon will not deal many times in his career. We present a case of a young patient with such an injury, who was treated with a corrective osteotomy and fixation, resulting in a very good outcome. This case report highlights the importance of surgical intervention for distal humerus fracture malunion. Read More

PLoS Negl Trop Dis 2022 04 29;16(4):e0010393. Epub 2022 Apr 29.

Post-Graduate Program in Neurology, Federal University of the State of Rio de Janeiro, Rio de Janeiro, Brazil.

Leprosy is still a prevalent disease in Brazil, representing 93% of all occurrences in the Americas. Leprosy neuropathy is one of the most worrying manifestations of the disease. Acute neuropathy usually occurs during reaction episodes and is called neuritis. Read More

Trop Med Infect Dis 2022 Apr 16;7(4). Epub 2022 Apr 16.

Unit of Hand Surgery and Microsurgery, Department of Musculoskeletal System, University Hospital of Modena, 41125 Modena, Italy.

Coronavirus disease 2019 (COVID-19) is the most dramatic pandemic of the new millennium. To counter it, specific vaccines have been launched in record time under emergency use authorization or conditional marketing authorization and have been subjected to additional monitoring. The European Medicines Agency recommend reporting any suspected adverse reactions during this additional monitoring phase. Read More

J Hand Surg Asian Pac Vol 2022 Apr 19;27(2):394-397. Epub 2022 Apr 19.

Department of Orthopedic Surgery, Wonkwang University Hospital, Iksan, South Korea.

Lymphoma is a malignant tumour of the lymphatic system. Neurolymphomatosis occurs when lymphoma cells invade the peripheral nervous system (PNS). Neurolymphomatosis has been reported involving the sciatic nerve, nerve roots and within the axilla and the upper arm. Read More

J Hand Surg Asian Pac Vol 2022 Apr 19;27(2):408-412. Epub 2022 Apr 19.

Department of Orthopaedic Surgery, Suwa Central Hospital, Nagano, Japan.

A fracture of the distal radius with an associated injury to the ulnar nerve is rare. The management of the ulnar nerve lesion is unclear. We present a patient with a closed distal radius fracture related to an injury to the ulnar nerve associated with diminished sensation and a claw deformity. Read More

BMC Musculoskelet Disord 2022 Apr 20;23(1):369. Epub 2022 Apr 20.

Department of Trauma and Microreconstructive Surgery, the First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Background: Tardy ulnar nerve palsy is a common late complication of traumatic cubitus valgus. At present, the treatment of tardy ulnar nerve palsy associated with traumatic cubitus valgus is still controversial, whether these two problems can be corrected safely and effectively in one operation is still unclear. To investigate the supracondylar shortening wedge rotary osteotomy combined with in situ tension release of the ulnar nerve in the treatment of tardy ulnar nerve palsy associated with traumatic cubitus valgus. Read More