253 results match your criteria Tumors of the Conus and Cauda Equina


Symptomatic mature teratoma of the lumbar spine: A case report.

Surg Neurol Int 2022 12;13:16. Epub 2022 Jan 12.

Department of Neurosurgery Allegheny General Hospital, Pittsburgh, Pennsylvania, United States.

Background: Teratomas are a unique family of tumors derived from two or more of the three embryonic layers: endoderm, mesoderm, and ectoderm. Mature teratomas are comprised the most well-differentiated tissue types and may contain skin, hair, teeth, smooth muscle, respiratory tissues, etc. Infrequently, mature teratomas may be found within the central nervous system and, in exceedingly rare cases, may be occur within the spinal cord itself (i. Read More

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January 2022

Elsberg Syndrome, Lumbosacral Radiculopathy, and Myelitis Due to Herpes Zoster in a Patient With Smoldering Myeloma.

J Investig Med High Impact Case Rep 2022 Jan-Dec;10:23247096211063348

Medical University of South Carolina, Charleston, USA.

Herpes zoster (HZ) is a common illness caused by the reactivation of latent varicella zoster virus (VZV) due to waning immunity, often secondary to old age or an underlying immunocompromised state. Its complications can manifest in variety of ways, including persistent neuralgias, vasculopathies, and stroke. Here, we describe a case of a 45-year-old man with a history of cryptogenic stroke and smoldering myeloma who was admitted with sacral HZ complicated by right lumbosacral radiculopathy and myelitis, otherwise known as Elsberg syndrome (ES). Read More

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January 2022

68Ga-FAPI PET/CT Findings in a Rare Presacral Myxopapillary Ependymoma.

Clin Nucl Med 2022 Apr;47(4):385-386

From the Department of Nuclear Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.

Abstract: Myxopapillary ependymoma is a rare tumor. Most of them occur exclusively in the conus medullaris, cauda equina, or filum terminale. Here, we present the 68Ga-FAPI PET/CT findings in a 37-year-old woman with presacral myxopapillary ependymoma. Read More

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Prognostic factors for progression-free survival of the filum terminale ependymomas in adults.

Neurochirurgie 2022 Apr 5;68(3):273-279. Epub 2022 Jan 5.

Service de Neurochirurgie, Hospices Civils de Lyon, Hôpital neurologique Pierre Wertheimer, 59, Bd Pinel, 69003 Lyon, France; Université de Lyon I, Université de Lyon, Lyon, France.

Objective: To define the prognostic factors for progression and to determine the impact of the histological grading (according to the World Health Organization) on the progression-free survival (PFS) of filum terminale ependymomas.

Methods: A retrospective chart review of 38 patients with ependymoma of the filum terminale was performed, focusing on demographic data, preoperative symptoms, tumor size, quality of resection, presence of a tumor capsule, and histological grade.

Results: Gross total resection (GTR) was achieved in 30 patients (78. Read More

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A critical analysis of surgery for occult tethered cord syndrome.

Childs Nerv Syst 2021 10 15;37(10):3003-3011. Epub 2021 Jul 15.

Department of Neurosurgery, Weill Cornell Medical Center, New York-Presbyterian Hospital, New York City, NY, USA.

Introduction: Tethered cord syndrome (TCS) is an amalgamation of neurological, urological, orthopedic, and dermatologic signs and symptoms with radiographic evidence of a thickened filum and low-lying conus. Surgical sectioning of the filum and disconnection of any tethering entities such as dermal sinus tracts or lipomas has been shown to improve outcomes. The manifestation of TCS symptoms in the absence of a low-lying conus has been referred to as occult tethered cord syndrome (OTCS) and is much less well reviewed in the literature. Read More

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October 2021

Two cases of myelin oligodendrocyte glycoprotein antibody-associated disease presenting with Cauda Equina Syndrome without conus myelitis.

Mult Scler Relat Disord 2021 Jul 8;52:103017. Epub 2021 May 8.

Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Guro-gu, Seoul 08308, Korea. Electronic address:

Myelin oligodendrocyte glycoprotein antibody-associated disorder (MOGAD) is a central nervous system inflammatory disorder associated with MOG antibodies. Two patients with clinical symptoms of cauda equina syndrome had positive serum MOG antibody tests, and spinal magnetic resonance imaging showed cauda equina enhancement. They were diagnosed with incomplete cauda equina syndrome associated with MOGAD. Read More

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Tumor Occupancy Ratio-An Imaging Characteristic Prognosticating the Surgical Outcome of Benign Intradural Extramedullary Spinal Cord Tumors.

Int J Spine Surg 2021 Jun 7;15(3):570-576. Epub 2021 May 7.

Department of Neurosurgery, Vivekananda Polyclinic and Institute of Medical Sciences, Lucknow, India.

Background: Intradural extramedullary (IDEM) spinal cord tumors are two thirds of all spinal tumors. We have prospectively analyzed the importance of the tumor occupancy ratio as a factor for predicting the course of the disease and in prognosticating the surgical outcome in patients with IDEM tumors.

Methods: We prospectively analyzed 44 consecutive cases of IDEM tumors, diagnosed as cervical, thoracic, and lumbar IDEM tumors (excluding conus/cauda equina lesion) by magnetic resonance imaging (MRI), that were operated on at our institution between 2014 and 2016. Read More

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Efficacy of intraoperative bulbocavernosus reflex monitoring for the prediction of postoperative voiding function in adult patients with lumbosacral spinal tumor.

J Clin Monit Comput 2022 04 8;36(2):493-499. Epub 2021 Mar 8.

Department of Neurology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82, Gumi-ro 173 Beon-gil, Bundang-Gu, Seongnam-Si, Geonggi-Do, Republic of Korea.

Lumbosacral spinal tumor surgery is associated with a relatively high risk of postoperative voiding dysfunction. This study aimed to investigate the correlation between intraoperative bulbocavernosus reflex (BCR) changes and postoperative voiding function in adult patients with lumbosacral spinal tumors. We retrospectively reviewed 63 patients who underwent intradural conus and cauda equina tumor surgeries with intraoperative BCR monitoring. Read More

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Lumbar Laminoplasty for Resection of Myxopapillary Ependymoma of the Conus Medullaris: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2021 04;20(5):E352

Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan, USA.

Myxopapillary ependymomas are slow-growing tumors that are located almost exclusively in the region of the conus medullaris, cauda equina, and filum terminale of the spinal cord. Surgical intervention achieving a gross total resection is the main treatment modality. If, however, a gross total resection cannot be achieved, surgery is augmented with radiation therapy. Read More

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Two cases of normal pressure hydrocephalus caused by ependymoma of the cauda equina.

Surg Neurol Int 2021 5;12. Epub 2021 Jan 5.

Department of Spinal Surgery, Kameda Medical Center, Kamogawa-Shi, Chiba, Japan.

Background: Normal pressure hydrocephalus (NPH) associated with tumors of the cauda equina is rare. Here, we report two cases of NPH attributed to cauda equina ependymomas.

Case Description: A 63-year-old male presented with progressive gait disturbance, dementia, and urinary incontinence. Read More

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January 2021

Familial tendency in patients with lipoma of the filum terminale.

Childs Nerv Syst 2021 05 7;37(5):1641-1647. Epub 2021 Jan 7.

Department of Neurosurgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata City, Osaka, 573-1010, Japan.

Purpose: Lipoma of the filum terminale (FL) is an abnormality in which fat is deposited in the filum terminale. This lipoma is often detected by skin abnormalities in the lumbosacral area such as a sacrococcygeal dimple. Some cases may develop tethered cord and become symptomatic. Read More

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Metastatic myxopapillary ependymoma treated with immunotherapy achieving durable response.

BMJ Case Rep 2020 Dec 17;13(12). Epub 2020 Dec 17.

Medical Oncology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia.

Myxopapillary ependymoma (MPE) is a rare glial tumour mainly located in the areas of the conus medullaris, cauda equina and filum terminale of the spinal cord. Ectopic MPE tends to behave more aggressively and distant metastases are often seen. Unfortunately, no standard treatment options are established as only small series of treated patients and a few reported cases are available in the literature. Read More

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December 2020

Whole-body 18-F-FDG-PET in patients with leptomeningeal disease and correlation with MRI.

Nucl Med Commun 2021 Feb;42(2):205-215

Department of Radiology, Nuclear Medicine Division, Mayo Clinic.

Objective: Studies evaluating leptomeningeal disease on whole-body 18F-FDG PET are lacking. The purpose was to evaluate PET imaging of leptomeningeal disease and investigate the incremental utility of newer PET reconstructions in leptomeningeal disease.

Methods: PET imaging of 56 patients with leptomeningeal disease detected initially on MRI (n = 53) or cytopathology (n = 35) were retrospectively reviewed. Read More

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February 2021

Atypical Imaging of Hemorrhagic Lumbosacral Myxopapillary Ependymoma with Histopathological Correlation: A Case Report.

Am J Case Rep 2020 Oct 21;21:e925449. Epub 2020 Oct 21.

Neurosurgery Division, Surgery Department, King Saud University Medical City (KSUMC), College of Medicine, King Saud University, Riyadh, Saudi Arabia.

BACKGROUND Spinal myxopapillary ependymoma (MPE) is a slow-growing tumor arising from ependymal cells of the central nervous system. MPE rarely presents with acute neurological compromise and most commonly occur in the filum terminale or conus medullaris region. To date, only a few cases have been reported of patients presenting acutely because of hemorrhagic MPE. Read More

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October 2020

Microsurgical resection of giant T11/T12 conus cauda equina schwannoma.

Bosn J Basic Med Sci 2021 Aug 1;21(4):383-385. Epub 2021 Aug 1.

Semmes Murphey Neurologic and Spine Institute, Memphis, TN, United States; Department of Neurosurgery, University of Tennessee Health Science Center, Memphis, TN, United States.

In this video, we highlight the anatomy involved with microsurgical resection of a giant T11/T12 conus cauda equina schwannoma. Spinal schwannoma remains the third most common intradural spinal tumor. Tumors undergoing gross total resection usually do not recur. Read More

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Primary intradural Hodgkin lymphoma of the conus medullaris and cauda equina: case report.

CNS Oncol 2020 09 29;9(3):CNS52. Epub 2020 Sep 29.

Department of Neurosurgery, Austin Health, Heidelberg, Victoria 3084, Australia.

Primary Hodgkin lymphoma of the central nervous system is an exceedingly rare condition with very few cases reported in the literature. Isolated intradural involvement of the spine is rarer still, with only two prior cases located in the extramedullary cervical and lumbosacral spine. We present a 48-year-old female who was presented with back pain, radiculopathy and a short history of sphincter disturbance and was subsequently found to have a lobulated homogenously enhancing exophytic lesion involving the conus medullaris and cauda equina on magnetic resonance imaging. Read More

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September 2020

[Clinical study of 21 cases of sacral cysts containing fila terminale].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Jun;52(3):582-585

Department of Neurosurgery, Peking University Third Hospital, Beijing 100191, China.

Objective: To summarize the characteristics of sacral cysts containing fila terminale and to explore the surgical treatment methods.

Methods: The clinical features, imaging characteristics and surgical methods of 21 cases of sacral cysts containing fila terminale from July 2010 to March 2017 were reviewed and analyzed. Lumbosacral and perineal pain, weakness of the lower limbs and bladder and bowel dysfunction were the common clinical symptoms. Read More

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Tailored therapy: Surgical and radiosurgical treatment for two distinct myxopapillary ependymomas in the same patient. A case report.

J Clin Neurosci 2020 Jul 20;77:237-239. Epub 2020 May 20.

Department of Neurosurgery, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Myxopapillary ependymomas are low grade neoplasms, which originate mostly from the medullary conus, cauda equina and the filum terminale. To date the principal treatment is surgical, total- or subtotal removal (GTR or STR), which can be associated with adjuvant radiotherapy. We report a patient with two tumor locations, one larger tumor at the L3 to S1 level and a smaller S2-S3 localized lesion. Read More

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Intramedullary-Extramedullary Breast Metastasis to the Caudal Neuraxis Two Decades after Primary Diagnosis: Case Report and Review of the Literature.

World Neurosurg 2020 08 11;140:26-31. Epub 2020 May 11.

Department of Neurosurgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

Background: Intramedullary metastases to the caudal neuraxis with exophytic extension to the extramedullary space are rare. We describe the unique case of a patient with locally recurrent breast cancer who developed an intramedullary-extramedullary metastasis to the conus medullaris and cauda equina 22 years after primary diagnosis, the longest interval between primary breast cancer and intramedullary spread to date. We also reviewed the published literature on focal breast metastases to the conus medullaris or cauda equina. Read More

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Sacral Extradural Angiolipoma Associated with Tight Filum Terminale and Spina Bifida Coexisting with Spinal Arteriovenous Fistula.

World Neurosurg 2020 08 11;140:37-45. Epub 2020 May 11.

Department of Radiology, Bumrungrad International Hospital, Bangkok, Thailand.

Background: Spinal arteriovenous fistula (AVF) may rarely associate with spinal dysraphism, that is, tethered spinal cord and spinal intradural lipoma. Spinal extradural angiolipoma coexisting with spinal AVF has not been reported in the literature. We reported an extremely rare case of sacral angiolipoma associated with tight filum terminale and sacral spina bifida coexisting with spinal AVF within this tumor. Read More

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Filum Terminale Ependymoma in an Infant with Meningocele.

Pediatr Neurosurg 2020 21;55(1):46-50. Epub 2020 Jan 21.

Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

This report describes a case of an ependymoma found in the setting of tethered cord syndrome. We present a 3-month-old girl with prenatal diagnosis of lumbar meningocele who later underwent tethered cord release. After birth, she was neurologically intact and only found to have a skin-covered meningocele. Read More

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November 2020

Natural reduction in acute intratumoral hemorrhage of spinal schwannoma in the cauda equina.

Nagoya J Med Sci 2019 Nov;81(4):701-705

Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

A 58-year-old woman presented with acute pain in her back and her left leg. Magnetic resonance imaging (MRI) revealed an intradural schwannoma with an intratumoral hemorrhage between the lower L4 vertebra and L5/S1 disk level. A follow-up MRI after one month revealed that the tumor had regressed from the middle of L5 to the L5/S1 disk level. Read More

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November 2019

Iatrogenic Lumbar Arachnoid Cyst Fenestration for Tethered Cord: 2-Dimensional Operative Video.

World Neurosurg 2020 Mar 12;135:130. Epub 2019 Dec 12.

Department of Neurological Surgery, Mayo Clinic Florida, Jacksonville, FL.

Iatrogenic lumbar arachnoid cysts are a rare occurrence after intradural surgery. To our knowledge, there is only 1 other previous case reported in the literature contributing to a symptomatic tethered cord. We present a surgical video (Video 1) demonstrating the history, preoperative workup, and operative technique for exploration and fenestration of a symptomatic iatrogenic lumbar arachnoid cyst with a tethered cord. Read More

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Filum terminale lipoma revealed by screening spinal ultrasonography in infants with simple sacral dimple.

Childs Nerv Syst 2020 05 5;36(5):1037-1042. Epub 2019 Dec 5.

Pediatrics, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Purpose: Spine ultrasound (US) examinations are widely performed in neonates and infants with sacral dimple to exclude associated congenital malformations. Increased utilization of, and improvements in, sonographic technology has resulted in the frequent identification of echogenic filum terminale (FT) containing fat below the conus medullaris, termed FT lipoma or fatty FT. We examined the value of screening US, especially for diagnosis of FT lipoma, in infants with "simple sacral dimple. Read More

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Ruptured dermoid cyst of the conus medullaris in the myelomeningocele sac revealed at the initial repair surgery.

Childs Nerv Syst 2020 05 28;36(5):1061-1065. Epub 2019 Nov 28.

Department of Neuropathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Dermoid cysts in the myelomeningocele (MMC) site are thought to arise in a delayed fashion because of iatrogenic implantation of dermoid elements at the time of the initial repair surgery. However, there have been few reports on dermoid elements already present at birth.

Clinical Presentation: We report a patient, in whom dermoid cyst was located at dorsal aspect of the conus medullaris in the MMC sac. Read More

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Intraoperative Neuromonitoring in Surgery of Cauda Equina and Conus Medullaris Tumors.

Turk Neurosurg 2019 ;29(6):909-914

Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Department of Neurology, Istanbul, Turkey.

Aim: To demonstrate the value of special intraoperative neuromonitoring techniques for cauda equina and conus medullaris tumors (CECMT) by describing standard methods used at our center.

Material And Methods: Neurophysiological records were retrospectively reviewed for 16 patients (eight females and eight males; age range: 27â€"60 years) who underwent surgery for CECMT at our department between 2016 and 2018.

Results: Motor and/or sensorial deficits were preoperatively identified in 10 patients; no patients had bladder or sexual dysfunction. Read More

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February 2020

Gangliocytic Paraganglioma of Dorsolumbar Spine: A Rare Tumor at Rare Site.

Asian J Neurosurg 2019 Jul-Sep;14(3):907-910

Department of Pathology, Mamata Medical College, Khammam, Telangana, India.

Spinal paragangliomas are rare benign tumors. The gangliocytic paragangliomas (GP) of spine are even rarer. The GPs are almost exclusively seen in duodenum. Read More

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September 2019

[Superficial siderosis of the central nervous system caused by myxopapillary ependymoma of conus medullaris and cauda equine: a case report and literature review].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Aug;51(4):769-774

Department of Neurology, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, Anhui, China.

Superficial siderosis of the central nervous system (SSCNS) is a rare disorder caused by hemosiderin deposits in the subpial layers of the brain and spinal cord due to prolonged or recurrent low-grade bleeding into the cerebrospinal fluid (CSF). Central nervous system tumor could be one of the sources of bleeding. Some problems exist at present regarding the diagnosis and treatment of SSCNS in China. Read More

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Intraoperative Triggered Electromyography Recordings from the External Urethral Sphincter Muscles During Spine Surgeries.

Cureus 2019 Jun 10;11(6):e4867. Epub 2019 Jun 10.

Neurosurgery, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, SAU.

Introduction: Bowel and bladder function are at risk during tumor resection and other surgeries of the conus, cauda equina, and nerve roots. This study demonstrates the ability to acquire triggered electromyography (t-EMG) from the external urethral sphincter (EUS) muscles by utilizing a urethral catheter with an electrode attached.

Methods: A retrospective analysis of neurophysiological monitoring data from two medical centers was performed. Read More

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