14,071 results match your criteria Tumors Orbital


Iris varix: 10-year experience with 28 eyes.

Indian J Ophthalmol 2019 Mar;67(3):350-357

Department of Ocular Tumor, Orbital Disease and Ophthalmic Radiation Therapy, The New York Eye Cancer Center, New York City, New York, USA.

Purpose: The purpose of this study is to describe the clinical characteristics, multimodality imaging findings, and clinical course of iris varices.

Methods: Retrospective, noncomparative, observational case series of 28 eyes of 26 patients with iris varices, diagnosed between 2007 and 2017, has been used.

Results: The mean (±SD) age was 58. Read More

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http://dx.doi.org/10.4103/ijo.IJO_1253_18DOI Listing

[Magnetic Resonance Imaging of the Orbital Cavity: Indications and Diagnostic Possibilities].

Klin Monbl Augenheilkd 2019 Feb 18. Epub 2019 Feb 18.

Today, magnetic resonance imaging (MRI) is considered the diagnostic tool of choice for eye and orbital pathologies. In this article, the MR image characteristics of relevant pathologies are illustrated with case-based examples in the context of clinical findings. Vascular pathologies (such as capillary and cavernous hemangioma), inflammatory diseases (such as endocrine orbitopathy), and neoplasms (such as lymphoma, uveal melanoma, retinoblastoma, and ocular/orbital metastasis) are described. Read More

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http://dx.doi.org/10.1055/a-0849-0000DOI Listing
February 2019

Neurocytoma mimicking macroadenoma.

Surg Neurol Int 2019 21;10. Epub 2019 Jan 21.

Department of Surgery and Anatomy, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Background: Intraventricular and extraventricular central neurocytomas (CN) are equally frequent among 20-40-year-old men and women. However, sellar and suprasellar extraventricular CN are extremely rare, with only 12 reported cases.

Case Description: The authors report the case of a Brazilian 27-year-old man who presented with progressive vision loss during the last 4 years and serious bilateral keratoconus. Read More

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http://dx.doi.org/10.4103/sni.sni_387_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357540PMC
January 2019

Outcomes of decompressive surgery for cavernous sinus meningiomas: long-term follow-up in 50 patients.

J Neurosurg 2019 Feb 15:1-8. Epub 2019 Feb 15.

1Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah; and.

OBJECTIVECavernous sinus meningiomas are complex tumors that offer a perpetual challenge to skull base surgeons. The senior author has employed a management strategy for these lesions aimed at maximizing tumor control while minimizing neurological morbidity. This approach emphasizes combining "safe" tumor resection and direct decompression of the roof and lateral wall of the cavernous sinus as well as the optic nerve. Read More

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http://dx.doi.org/10.3171/2018.10.JNS181480DOI Listing
February 2019
1 Read

Recommendations for ultrasound examination in ophthalmology. Part II: Orbital ultrasound.

J Ultrason 2018 ;18(75):349-354

Imperial College NHS Trust, Western Eye Hospital , London , UK.

Pathological processes within the orbits are a heterogeneous group of diseases of various etiologies, clinical pictures and therapy models. Due to poor access to the orbits in a clinical examination, imaging plays a significant role in both diagnosis and treatment monitoring in patients with an orbital pathology. One of such imaging modalities is ultrasonography. Read More

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http://jultrason.pl/index.php/issues/volume-18-no-75/recomme
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http://dx.doi.org/10.15557/JoU.2018.0051DOI Listing
January 2018
4 Reads

Pseudocystic appearance of an orbital carcinoid metastasis.

Orbit 2019 Feb 12:1-4. Epub 2019 Feb 12.

a Department of Ophthalmology & Visual Sciences , University of Adelaide , Adelaide , Australia.

Carcinoid tumours are a low-grade neuroendocrine malignancy that infrequently metastisizes to orbital structures. The typical radiological appearance of carcinoid is a solid, well-circumscribed mass that enhances with contrast. We present a case of orbital carcinoid metastasis with pseudocystic radiological appearance and review of the literature. Read More

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http://dx.doi.org/10.1080/01676830.2019.1576739DOI Listing
February 2019

Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland.

Oncotarget 2019 Jan 11;10(4):480-493. Epub 2019 Jan 11.

Dr. Nasser Al-Rashid Orbital Vision Research Center, Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Identification of molecular targets is the first step in developing efficacious therapeutic strategies for tumors. A tumors' biological response to perturbagens yields important information on the molecular determinants for tumor growth. The aim of this study was to characterize the response of adenoid cystic carcinoma of the lacrimal gland (LGACC) to intra-arterial cytoreductive chemotherapy (IACC) in order to identify novel targets to enhance therapy. Read More

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http://dx.doi.org/10.18632/oncotarget.26558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355187PMC
January 2019

IgG4-related disease: what a hematologist needs to know.

Haematologica 2019 Jan 31. Epub 2019 Jan 31.

Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, Canada.

IgG4-related disease is a fibroinflammatory condition that can affect nearly any organ system. Common presentations include major salivary and lacrimal gland enlargement, orbital disease, autoimmune pancreatitis, retroperitoneal fibrosis and tubulointerstitial nephritis. This review focuses on the hematological manifestations of IgG4-related disease, including lymphadenopathy, eosinophilia, and polyclonal hypergammaglobulinemia. Read More

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http://dx.doi.org/10.3324/haematol.2018.205526DOI Listing
January 2019
2 Reads

[Orbital Manifestation of IgG4-Related Disease: Three Case Reports].

Klin Monbl Augenheilkd 2019 Jan 28;236(1):25-30. Epub 2019 Jan 28.

Klinik und Poliklinik für Neuroradiologie, Johannes Gutenberg-Universität Universitätsmedizin, Mainz.

IgG4-related orbital disease is rare. It belongs to an entity of a multisystemic disorder - IgG4-related disease - which has emerged recently. Differential diagnosis comprises idiopathic orbital inflammation, endocrine orbitopathy and orbital neoplasms. Read More

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http://dx.doi.org/10.1055/a-0825-6550DOI Listing
January 2019

Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14223

Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.

Rationale: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms with only a few reported cases affecting the nasal cavity, paranasal sinuses, and anterior skull base.

Patient Concerns: A 12-year-old girl with a mass in her nose was admitted to the Department of Otorhinolaryngology of Shenzhen Children's Hospital. She had a 4-month history of progressive, unilateral right nasal obstruction, unilateral mucopurulent rhinorrhea, foul nasal odor, snoring, hyposmia, occasional epistaxis, and no headache, no facial numbness, without eye swelling and vision loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358413PMC
January 2019
3 Reads
5.723 Impact Factor

Orbital paraganglioma in a dog.

Tierarztl Prax Ausg K Kleintiere Heimtiere 2018 Dec 18;46(6):410-415. Epub 2019 Jan 18.

A 10-year-old Rottweiler presented with right-sided moderately painful exophthalmia, blindness, absence of dazzle and pupillary light reflexes, a swollen optic nerve head and ventrolateral indentation of the globe. On magnetic resonance imaging, a 3 x 2 x 2 cm mass with a fluid filled center and contrast-enhancing periphery was noted posteriolateral of the globe. Orbital ultrasound was used for a guided fine needle aspirate of the mass. Read More

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http://dx.doi.org/10.1055/s-0038-1677406DOI Listing
December 2018
3 Reads

Conjuctival lesions - the relationship of papillomas and squamous cell carcinoma to HPV infection.

Cesk Slov Oftalmol 2018 ;74(3):92-97

The etiology of papilloma formation is multifactorial. There is a strong association between human papillomavirus (HPV) and the development of these conjunctival lesions. HPV is tumorigenic and commonly produces benign tumors with low malignant potential. Read More

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http://www.cs-ophthalmology.cz/en/journal/2018/3/2
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http://dx.doi.org/10.31348/2018/1/2-3-2018DOI Listing
January 2018
3 Reads

Proximal Branches of the Anterior Cerebral Artery: Anatomic Study and Applications to Endoscopic Endonasal Surgery.

Oper Neurosurg (Hagerstown) 2019 Jan 12. Epub 2019 Jan 12.

Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Background: The endoscopic endonasal approach is a surgical alternative for midline anterior skull base tumors. A detailed understanding of the proximal anterior cerebral artery (ACA) branches' anatomy from an endonasal perspective is essential for avoiding vascular complications.

Objective: To evaluate, from an endonasal perspective, the anatomic variations of the ACA and its proximal branches, specifically the recurrent artery of Heubner (RAH), and the fronto-orbital (FOA) and frontopolar (FPA) arteries. Read More

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http://dx.doi.org/10.1093/ons/opy308DOI Listing
January 2019

Eye-Sparing Treatment for Diffuse Invasive Conjunctival Melanoma.

Ocul Oncol Pathol 2018 Jun 1;4(4):261-266. Epub 2018 Feb 1.

Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.

The management of patients with diffuse invasive conjunctival melanoma focuses on local tumor control and screening for metastasis. Despite the lack of consensus on the benefit of sentinel lymph node biopsy for these neoplasms, the information obtained by histopathology is useful for tumor staging and treatment planning. Due to the lack of evidence of survival improvement, orbital exenteration is being performed with diminishing frequency. Read More

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http://dx.doi.org/10.1159/000485978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322084PMC
June 2018
1 Read

Sphenoid Wing Meningiomas: Surgical Outcomes in a Series of 141 Cases and Proposal of a Scoring System Predicting Extent of Resection.

World Neurosurg 2019 Jan 11. Epub 2019 Jan 11.

Department of Neurosurgery, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul, Turkey.

Objective: Sphenoid wing meningiomas are the third most common group of intracranial meningiomas. Their management is a challenge because of their bone invasion potential and their proximity to neurovascular structures and the cavernous sinus.

Methods: A cohort of 141 patients with sphenoid wing meningioma who were operated on and followed up between 1986 and 2018 were retrospectively analyzed. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.175DOI Listing
January 2019

Lacrimal gland pleomorphic adenoma: a review of 52 cases, 15-year experience.

Acta Otolaryngol 2019 Jan 10:1-5. Epub 2019 Jan 10.

a Department of Otolaryngology - Orbital Surgery , Clinica Clarós , Barcelona , Spain.

Background: Lacrimal gland (LG) tumours are rare neoplasms. Pleomorphic adenoma (PA) is the most common histologic variant, representing ∼20% of all LG tumours. PA tends to recur leading to great morbidity. Read More

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http://dx.doi.org/10.1080/00016489.2018.1541362DOI Listing
January 2019
2 Reads

Successful management of recurrent adenoid cystic carcinoma in the deep infratemporal fossa by maxillo-orbito-zygomatic approach.

Auris Nasus Larynx 2019 Jan 6. Epub 2019 Jan 6.

Department of Head and Neck Surgery. Electronic address:

Objective: In the case of deep invasion of an infratemporal fossa (ITF) tumor, surgeons find it difficult to gain sufficient visualization and working space by conventional surgical approaches. To overcome these limitations, we have developed a novel surgical technique, maxillo-orbito-zygomatic (MOZ) approach, by combining partial lateral maxillectomy with the conventional orbito-zygomatic approach.

Methods: A 63-year-old male presented with the fifth recurrent adenoid-cystic carcinoma in the right deep ITF. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03858146183026
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http://dx.doi.org/10.1016/j.anl.2018.12.010DOI Listing
January 2019
2 Reads

Transoral Finger-Retraction for Endonasal Endoscopic Resection of Masseteric and Buccal Space Lesions.

J Craniofac Surg 2018 Dec 29. Epub 2018 Dec 29.

Department of Otolaryngology - Head and Neck Surgery.

Lesions involving the masseteric and buccal spaces have traditionally required transoral or transcervical approaches. Herein, the authors describe the successful endonasal endoscopic resection of a juvenile nasopharyngeal angiofibroma (JNA) with significant extension into the masseteric and buccal spaces facilitated by transoral finger retraction. Juvenile nasopharyngeal angiofibromas are hypervascular tumors originating in the pterygopalatine fossa (PPF) with complex relationships to skull base and orbital structures. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004931DOI Listing
December 2018

A large primary orbital lymphoma with proptosis: A case report and review.

Surg Neurol Int 2018 4;9:249. Epub 2018 Dec 4.

Department of Neurosurgery, Max Superspeciality Hospital, Saket, New Delhi, India.

Background: Primary orbital lymphomas are a rare subset of tumors constituting 1-2% of non-Hodgkin's lymphoma. They are mostly indolent B-cell lymphomas presenting with gradual progressive proptosis, decreased visual acuity, restricted ocular mobility, and diplopia. The role of surgery is mainly for obtaining a biopsy. Read More

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http://dx.doi.org/10.4103/sni.sni_270_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293602PMC
December 2018
1 Read

Navigation-Guided Endoscopy Combined with Deep Lateral Orbitotomy for Removal of Small Tumors at the Lateral Orbital Apex.

J Ophthalmol 2018 25;2018:2827491. Epub 2018 Nov 25.

Minimally Invasive Surgical Center, The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.

Purpose: To evaluate the efficacy, feasibility, and safety of the navigation-guided endoscopy combined with deep lateral orbitotomy for removal of small tumors at the lateral orbital apex.

Design: A retrospective, noncomparative case series.

Methods: Retrospective analysis of ten patients (10 eyes) with small tumors at the lateral orbital apex comprised navigation-guided endoscopy combined with deep lateral orbitotomy at the Eye Hospital of Wenzhou Medical University from November 2015 to November 2017. Read More

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https://www.hindawi.com/journals/joph/2018/2827491/
Publisher Site
http://dx.doi.org/10.1155/2018/2827491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286765PMC
November 2018
4 Reads

Metalloporphyrin Complex-Based Nanosonosensitizers for Deep-Tissue Tumor Theranostics by Noninvasive Sonodynamic Therapy.

Small 2019 Feb 27;15(5):e1804028. Epub 2018 Dec 27.

Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab for Biomaterials, Shenzhen Engineering Laboratory of Nanomedicine and Nanoformulations, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences, Shenzhen, 518055, P. R. China.

Metal complexes are widely used as anticancer drugs, while the severe side effects of traditional chemotherapy require new therapeutic modalities. Sonodynamic therapy (SDT) provides a significantly noninvasive ultrasound (US) treatment approach by activating sonosensitizers and initiating reactive oxygen species (ROS) to damage malignant tissues. In this work, three metal 4-methylphenylporphyrin (TTP) complexes (MnTTP, ZnTTP, and TiOTTP) are synthesized and encapsulated with human serum albumin (HSA) to form novel nanosonosensitizers. Read More

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http://dx.doi.org/10.1002/smll.201804028DOI Listing
February 2019

Tumor Resection Guided by Intraoperative Indocyanine Green Dye Fluorescence Angiography Results in Negative Surgical Margins and Decreased Local Recurrence in an Orthotopic Mouse Model of Osteosarcoma.

Ann Surg Oncol 2019 Mar 27;26(3):894-898. Epub 2018 Dec 27.

Musculoskeletal Oncology Laboratory, Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA, USA.

Background: Surgical resection with negative margins is the foundation of extremity sarcoma management. Failure to achieve negative surgical margins can result in local recurrence (LR), a potentially devastating complication. Indocyanine green (ICG) is a US FDA-approved fluorophore previously used to guide carcinoma resections. Read More

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http://dx.doi.org/10.1245/s10434-018-07114-9DOI Listing
March 2019
1 Read
3.930 Impact Factor

Sino-orbital desmoid tumor in a pediatric patient - Case report with review of literature.

Orbit 2018 Dec 27:1-9. Epub 2018 Dec 27.

e Department of Pediatric Oncology , National University Health System , Singapore , Singapore.

We report a case of a 2-year-old female who presented with bilateral progressive proptosis, visual loss, nasal obstruction, and breathing difficulty. Magnetic resonance imaging revealed a large sino-orbital mass that was extending to the orbital apex and skull base. An initial diagnosis of rhabdomyosarcoma was made elsewhere on the basis of the presence of round and spindle cell tumor. Read More

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http://dx.doi.org/10.1080/01676830.2018.1556306DOI Listing
December 2018
2 Reads

Oral Hedgehog Pathway Inhibition as a Means for Ocular Salvage in Locally Advanced Intraorbital Basal Cell Carcinoma.

Dermatol Surg 2019 01;45(1):17-25

All authors are affiliated with the University of Rochester Medical Center, Rochester, New York.

Background: Basal cell cancer is the most common cutaneous malignancy. It rarely presents with locally advanced or metastatic disease. Rare presentations such as intraorbital invasion remain a difficult clinical problem with significant potential morbidity. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001640DOI Listing
January 2019
1 Read

Choroidal melanoma masquerading as orbital cellulitis.

BMJ Case Rep 2018 Dec 9;11(1). Epub 2018 Dec 9.

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.

Orbital cellulitis is the most common subset of orbital inflammatory disease. We describe a patient with necrotic choroidal melanoma who presented with orbital cellulitis. MRI revealed a mass lesion suggesting intraocular melanoma with no extrascleral extension. Read More

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http://dx.doi.org/10.1136/bcr-2018-227486DOI Listing
December 2018

Rhabdomyoblastic differentiation in rosai dorfman disease of the orbit in a 12-year-old male.

Niger J Clin Pract 2018 Dec;21(12):1670-1673

Department of Ophthalmology, Federal Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.

Extranodal Rosai-Dorfman disease involving the orbit has been reported severally with extensive discourse on management strategies. However, rhabdomyoblastic differentiation coexisting with the disease is yet unreported. We present the clinical and histopathological features of a 12-year-old boy presenting with both. Read More

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http://dx.doi.org/10.4103/njcp.njcp_262_17DOI Listing
December 2018
7 Reads

Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis.

BMC Cancer 2018 Dec 17;18(1):1262. Epub 2018 Dec 17.

Orbital Service, Moorfields Eye Hospital, City Road, London, EC1V 2PD, UK.

Background: Ocular melanoma is a rare but often deadly malignancy that arises in the uvea (commonest primary site), conjunctiva or the orbit. Primary orbital melanoma (POM) is exceedingly rare, with approximately 60 cases reported to date. Despite recent advances in our understanding of the genetics of primary uveal and conjunctival melanomas, this information is lacking for POM. Read More

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https://bmccancer.biomedcentral.com/articles/10.1186/s12885-
Publisher Site
http://dx.doi.org/10.1186/s12885-018-5190-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297940PMC
December 2018
1 Read

[Application of image-guided system in endoscopic sinus and skull base surgery].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1856-1859

Department of Otorhinolaryngology Head and Neck Surgery, Huadong Hospital, Fudan University, Shanghai, 200040,China.

To evaluate the applicative value of image-guided system in endoscopic sinus and skull base surgeries. A total of 103 endoscopic surgical procedures were performed.All these procedures were conducted with the utilization of image-guided system, among which there were 92 cases of sinonasal-skull base surgery(including nasal sinuses resection of benign and malignant tumors involving skull base lesions, the cumulative orbital lesion resection of nasal sinus lesions, etc. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.24.003DOI Listing
December 2018
2 Reads

Endoscopic transorbital surgery for Meckel's cave and middle cranial fossa tumors: surgical technique and early results.

J Neurosurg 2018 Nov 1:1-10. Epub 2018 Nov 1.

Departments of1Neurosurgery.

OBJECTIVETumors involving Meckel's cave remain extremely challenging because of the surrounding complex neurovascular structures and deep-seated location. The authors investigated a new minimal-access technique using the endoscopic transorbital approach (eTOA) through the superior eyelid crease to Meckel's cave and middle cranial fossa lesions and reviewed the most useful surgical procedures and pitfalls of this approach.METHODSBetween September 2016 and January 2018, the authors performed eTOA in 9 patients with tumors involving Meckel's cave and the middle cranial fossa. Read More

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http://dx.doi.org/10.3171/2018.6.JNS181099DOI Listing
November 2018
3 Reads

The treatment results in patients with lmphoma disease in the orbit.

Cesk Slov Oftalmol 2018 ;73(5-6):211-217

Introduction: Lymphoma is a malignant disease that can affect several structures of the orbit and eye adnexa. In the area of orbit the non-Hodgkins lymphoma (NHL) is typical, which may be indolent or aggressive. Indolent subtypes include MALT (mucosa-associated lymphoid tissue), follicular lymphoma (FL), lymphoplasmocytic lymphoma (LPL). Read More

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January 2018
2 Reads

Optic nerve orbital meningioma.

Cesk Slov Oftalmol 2018 ;74(1):23-30

Introduction: Orbital meningioma treatment has achieved significant success over the last period. Primary optic nerve sheath meningiomas by the clinically progressive finding, but still persistent sufficient visual acuity, can be treated by fractionated stereotactic radiotherapy. Surgery is indicated for secondary meningiomas of the orbit. Read More

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January 2018

The eye of the beholder: orbital metastases from midgut neuroendocrine tumors, a two institution experience.

Cancer Imaging 2018 Dec 6;18(1):47. Epub 2018 Dec 6.

Department of Internal Medicine, Stanford University Medical Center, Stanford, CA, USA.

Background: Metastases to the orbit occur rarely in midgut neuroendocrine tumor (NET) patients with only 20 cases reported to date. Patients typically present with bilateral involvement of the recti muscles and experience symptoms such as diplopia, proptosis, and decreased vision. Although orbital MRI remains the gold standard for imaging orbital disease, many orbital lesions are now detected on somatostatin-receptor (SSTR) based imaging such as 68Ga-DOTATATE PET-CT. Read More

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http://dx.doi.org/10.1186/s40644-018-0181-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282338PMC
December 2018
1 Read

Basal cell carcinoma and basosquamous carcinoma, two faces of the same condition?

Rom J Morphol Embryol 2018 ;59(3):989-996

Department of Microscopic Morphology, "Victor Babeş" University of Medicine and Pharmacy, Timişoara, Romania; Department of Otorhinolaryngology, "Victor Babeş" University of Medicine and Pharmacy, Timişoara, Romania;

Basal cell carcinoma (BCC) is the most common locally invasive malignant epidermal neoplasm. It is generally a tumor that runs a slow progressive course and can usually be cured by surgery. Basosquamous carcinoma is considered by some authors a rare subtype of BCC, while others describe it as independent tumor with different evolution from BCC. Read More

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January 2019
5 Reads

Mixed (nodular and morpheic) upper eyelid basal cell carcinoma with orbital invasion - histological and clinical features.

Rom J Morphol Embryol 2018 ;59(3):977-983

Department of Plastic Surgery, "Grigore T. Popa" University of Medicine and Pharmacy, Iaşi, Romania;

Basal cell carcinoma (BCC) is the most common type of cancer located in the periocular area. We will present the clinical case of a 63-year-old male patient who was admitted to the 2nd Clinic of Neurosurgery, "Prof. Dr. Read More

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January 2019
6 Reads

Long-term seizure outcome in frontal lobe epilepsy surgery.

Epilepsy Behav 2019 Jan 3;90:93-98. Epub 2018 Dec 3.

IRCCS "NEUROMED", Pozzilli, IS, Italy; Department of Neurology and Psychiatry, "Sapienza" University of Rome, Italy.

Purpose: The purpose of this study was to report long-term seizure outcome in patients who underwent frontal lobe epilepsy (FLE) surgery.

Method: This retrospective study included 44 consecutive subjects who underwent resective surgery for intractable FLE at IRCCS NEUROMED (period 2001-2014), followed up for at least 2 years (mean: 8.7 years). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15255050183074
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http://dx.doi.org/10.1016/j.yebeh.2018.10.033DOI Listing
January 2019
13 Reads
2.257 Impact Factor

An unusual orbital tumor in an adult: Granuloma annulare.

Am J Ophthalmol Case Rep 2019 Mar 14;13:9-12. Epub 2018 Nov 14.

MUHC - McGill University Ocular Pathology Laboratory, 1001 Boul Decarie, Block E, E02.6217, Montreal, QC, H4A 3J1, Canada.

Purpose: Granuloma annulare (GA) is a rare clinical entity that does not classically arise from the peri-orbital area in adults. The purpose of this case report is to present a 69-year-old female with GA of the orbit. As well, the pathological and immunohistochemical features of these tumors will be discussed. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247445PMC
March 2019
3 Reads

Gallbladder Metastasis From Conjunctival Melanoma.

Clin Nucl Med 2019 Feb;44(2):e107-e109

From the Department of Nuclear Medicine, Institut Curie, PSL Research University, Paris, France.

Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. Read More

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http://Insights.ovid.com/crossref?an=00003072-900000000-9732
Publisher Site
http://dx.doi.org/10.1097/RLU.0000000000002413DOI Listing
February 2019
8 Reads

Imaging predictors for malignant transformation of inverted papilloma.

Laryngoscope 2018 Dec 4. Epub 2018 Dec 4.

Department of Otolaryngology-Head and Neck Surgery, Stanford, California.

Objectives/hypothesis: Inverted papillomas (IPs) are benign tumors of the sinonasal tract with a malignant transformation potential. Predicting the transformation propensity of IPs and corresponding risk factors has long been a challenge. In this study, we aimed to use radiographic findings on magnetic resonance imaging (MRI) and computed tomography (CT) to help differentiate IP from IP-transformed squamous cell carcinomas (IP-SCC). Read More

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http://dx.doi.org/10.1002/lary.27582DOI Listing
December 2018
18 Reads

Impact of Unilateral Orbital Radiotherapy on the Structure and Function of Bilateral Human Meibomian Gland.

J Ophthalmol 2018 25;2018:9308649. Epub 2018 Oct 25.

Department of Radiotherapy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China.

Background: Radiotherapy (RT) has widely been used to treat ocular tumors, yet the impact of orbital radiation to the meibomian gland has rarely been studied. Our study aims at evaluating the bilateral meibomian gland structure and function 12 months after unilateral orbital RT in patients with ocular tumors.

Methods: An observational case-control study. Read More

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https://www.hindawi.com/journals/joph/2018/9308649/
Publisher Site
http://dx.doi.org/10.1155/2018/9308649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222211PMC
October 2018
5 Reads

Synchronous orbital and mandibular metastases from squamous cell carcinoma of lung as initial disease presentation in a young female: First report of a rare occurrence.

J Cancer Res Ther 2018 Oct-Dec;14(6):1425-1427

Department of Radiation Oncology, All India Institute of Medical Sciences, New Delhi, India.

Metastatic tumor to orbit or mandible as initial presentation is rare. According to the available literature, majority of these described cases had its origin from lung and breast. Adenocarcinoma is the most commonly described histology. Read More

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http://www.cancerjournal.net/preprintarticle.asp?id=199429
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http://dx.doi.org/10.4103/0973-1482.199429DOI Listing
February 2019
4 Reads

Asymmetric lacrimal gland enlargement: an indicator for detection of pathological entities other than thyroid eye disease.

Graefes Arch Clin Exp Ophthalmol 2019 Feb 28;257(2):405-411. Epub 2018 Nov 28.

Department of Oculoplastic, Orbital, and Lacrimal Surgery, Aichi Medical University Hospital, 1-1 Yazako-Karimata, Nagakute, Aichi, 480-1195, Japan.

Purpose: To examine the clinicopathological characteristics of patients with thyroid eye disease (TED) who showed asymmetric lacrimal gland enlargement.

Methods: Sixteen patients were included in this retrospective, observational case series. The following data were collected: sex, age, laterality, past medical history, laboratory results for thyroid function and other autoimmune disorders, pathological results, other systemic lesions related to lacrimal gland pathology, and the clinical course after treatment. Read More

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http://dx.doi.org/10.1007/s00417-018-4197-0DOI Listing
February 2019
1 Read

A rare case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma.

Ear Nose Throat J 2018 Oct-Nov;97(10-11):E32-E35

Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama 380-8550, Japan.

Lacrimal sac tumors are rare and difficult to diagnose. We present a case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma in a 73-year-old woman who presented with swelling of the inner canthus. Biopsy identified the growth as an adenocarcinoma. Read More

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November 2018
1 Read

Neonatal Teratoma: Craniofacial Treatment.

J Craniofac Surg 2019 Jan;30(1):e17-e19

Department of Plastic Surgery, Baby Memorial Hospital.

Teratomas are rare congenital neoplasms. Head and neck locations of the tumor are uncommon with combined intracranial and extracranial extensions being even more rare. The authors present a case of teratoma involving the temporal, buccal, maxillary, orbital and extending to the intracranial regions, which was successfully managed by surgical resection. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004906DOI Listing
January 2019
2 Reads

Erdheim Chester disease in a patient with Burkitt lymphoma: a case report and review of literature.

Diagn Pathol 2018 Nov 24;13(1):94. Epub 2018 Nov 24.

Department of Pathology, The Ohio State University Wexner Medical Center, 410 W. 10th Ave, N#308, Columbus, OH, 43210, USA.

Background: Erdheim Chester disease (ECD) is a rare, non-Langerhans cell histiocytosis characterized by widespread tissue infiltration by CD68-positive, CD1a-negative foamy histiocytes. ECD can be difficult to identify, and diagnosis relies on the presence of histiocytes with certain histologic and immunophenotypic features in an appropriate clinical and radiologic setting. Clinical signs and symptoms are variable depending on which organ systems are involved. Read More

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https://diagnosticpathology.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13000-018-0772-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260675PMC
November 2018
8 Reads

Chondrosarcoma in the Petrous Apex: Case Report and Review.

J Neurol Surg Rep 2018 Oct 18;79(4):e83-e87. Epub 2018 Oct 18.

Division of Neurosurgery, Department of Surgery, The Ottawa Hospital, Ottawa, Canada.

 Surgical treatment of petrous apex chondrosarcoma is challenging due to the location of the tumor. Using an endoscopic technique for tumor resection is favored since it provides a minimally invasive approach.  A 57 years old female was admitted for acute onset of left abducens nerve palsy and occasional headache mainly on the left side of the retro-orbital area with some radiation to the left occiput. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1673627
Publisher Site
http://dx.doi.org/10.1055/s-0038-1673627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193802PMC
October 2018
8 Reads

Giant cell tumour of frontal bone in a patient with bilateral retinoblastoma.

Arch Soc Esp Oftalmol 2018 Nov 15. Epub 2018 Nov 15.

Unidades de Oculoplastia-órbita, RETICS OftaRed, Instituto de Salud Carlos III, Madrid, España; Unidades de Retina y Oncología Ocular, UGC Oftalmología, Hospital Universitario Virgen Macarena, Sevilla, España.

A case is presented of a 5 year-old patient with bilateral hereditary retinoblastoma treated with radiotherapy in the right eye and enucleation of the left eye. After three years without evidence of progression, the patient presented with a right orbital mass that compromised the frontal bone. After surgical excision, the histology analysis was consistent with a diagnosis of giant cell tumour. Read More

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http://dx.doi.org/10.1016/j.oftal.2018.10.003DOI Listing
November 2018
1 Read

Fibromyxoma of the Orbit.

J Craniofac Surg 2019 Jan;30(1):e19-e21

Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Fibromyxomas are rare tumors that are not commonly seen in the orbit. The authors present a case of orbital fibromyxoma. A 42-year-old male presented with proptosis of the right eye that began 1 month prior. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004950DOI Listing
January 2019
2 Reads

[Ultrasound diagnosis and differential diagnosis of medium and small choroidal melanomas].

Zhonghua Yan Ke Za Zhi 2018 Nov;54(11):843-848

Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Lab., Beijing Key Lab. of Intraocular Tumor Diagnosis and Treatment, Beijing 100730, China.

To analyze the ultrasound diagnosis and differential diagnosis of medium and small choroidal melanomas. It was a retrospective case series study. Thirty-six cases (36 eyes) with medium or small choroidal melanoma were collected between January 2016 and January 2017 in Beijing Tongren Hospital, including 16 males and 20 females aged (50±12) years old. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2018.11.009DOI Listing
November 2018
9 Reads

Recurrent epibulbar dermoid cyst treated with amniotic membrane implant a case report.

BMC Surg 2018 Nov 14;18(1):98. Epub 2018 Nov 14.

Department of Cellular Biology and Tissue Engineering, Faculty of Medicine and Psychology, Autonomous University of Baja California, Av. Universidad no 14418, Parque Industrial Internacional Tijuana, CP. 22390, Tijuana, BC, Mexico.

Background: The dermoid cyst considered a cystic teratoma derived from embryonic germinal epithelium is a slow-growing benign tumour. Dermoid cysts may occur in the orbital and periorbital region in paediatric patients and are often recurrent. The surgical approach depends upon the site of the lesion, superficial or deep. Read More

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https://bmcsurg.biomedcentral.com/articles/10.1186/s12893-01
Publisher Site
http://dx.doi.org/10.1186/s12893-018-0426-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236942PMC
November 2018
10 Reads