229 results match your criteria Tufted Angioma


Tufted angioma with Kasabach-Merritt syndrome: Two cases successfully treated with everolimus.

Pediatr Blood Cancer 2020 Jun 10;67(6):e28291. Epub 2020 Apr 10.

Department of Dermatology, Mohammed VI University Hospital Center, Cadi Ayyad University, Marrakech, Morocco.

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http://dx.doi.org/10.1002/pbc.28291DOI Listing

Immunohistochemical Analysis of mTOR Pathway-Related Proteins in Kaposiform Hemangioendothelioma.

Dermatology 2020 2;236(3):262-270. Epub 2020 Jan 2.

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China.

Background: Mammalian target of rapamycin (mTOR) inhibitors have been shown to have excellent effects in the management of kaposiform hemangioendothelioma (KHE); however, the mechanism of action is unclear. This study identified the expressions of mTOR pathway-related proteins in different vascular tumors to provide insight into the pathogenesis of KHE.

Methods: We retrospectively reviewed the pathologic specimens of 30 patients (KHE, 15; tufted angioma [TA], 5; infantile hemangioma [IH], 5; and lymphatic malformation [LM], 5). Read More

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http://dx.doi.org/10.1159/000503604DOI Listing
January 2020

Kaposiform hemangioendothelioma and tufted angioma - (epi)genetic analysis including genome-wide methylation profiling.

Ann Diagn Pathol 2020 Feb 10;44:151434. Epub 2019 Dec 10.

Department of Pathology, Radboud University Medical Center, Nijmegen, the Netherlands; Princess Màxima Center for Pediatric Oncology, Utrecht, the Netherlands. Electronic address:

Kaposiform hemangioendothelioma (KHE) is a locally aggressive vascular condition of childhood and is clinicopathologically related to tufted angioma (TA), a benign skin lesion. Due to their rarity molecular data are scarce. We investigated 7 KHE and 3 TA by comprehensive mutational analysis and genome-wide methylation profiling and compared the clustering, also with vascular malformations. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2019.151434DOI Listing
February 2020

Tufted angioma presenting with subclinical coagulopathy.

Dermatol Online J 2019 Sep 15;25(9). Epub 2019 Sep 15.

Department of Dermatology, Wake Forest Baptist Medical Center, Winston Salem, NC.

Tufted angioma is a rare, benign vascular tumor of uncertain pathogenesis, characterized histopathologically by "tufts" of capillaries within the dermis. A life-threatening coagulopathy, Kasabach-Merritt phenomenon, occurs in approximately 10% of cases of tufted angioma and is characterized by profound thrombocytopenia and fibrinogen consumption. We present an asymptomatic 10-month-old boy who presented with an erythematous patch of the right upper extremity and subsequently was diagnosed by biopsy with tufted angioma. Read More

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September 2019

Oral itraconazole for the treatment of giant tufted angioma with hair loss arising during pregnancy: A case report.

J Dermatol 2020 Feb 14;47(2):e35-e36. Epub 2019 Nov 14.

Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1111/1346-8138.15144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7027534PMC
February 2020

What is new in endothelial neoplasia?

Virchows Arch 2020 Jan 28;476(1):17-28. Epub 2019 Aug 28.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, USA.

The classification of vascular neoplasms continues to evolve as we accumulate more genetic and clinical data, particularly for rare tumor types. Because of tumor rarity, changes to classification schema, overlapping histologic features, and in some cases, lack of morphologic evidence of vasoformation, vascular neoplasms present a diagnostic challenge. Here, we discuss recent developments in our understanding of vascular tumors, with a detailed discussion of epithelioid hemangioma, tufted angioma, kaposiform hemangioendothelioma, composite hemangioendothelioma, pseudomyogenic hemangioendothelioma, epithelioid hemangioendothelioma, and angiosarcoma. Read More

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http://dx.doi.org/10.1007/s00428-019-02651-4DOI Listing
January 2020
1 Read

Tufted angioma with associated Kasabach-Merritt phenomenon caused by somatic mutation in GNA14.

Pediatr Dermatol 2019 Nov 18;36(6):963-964. Epub 2019 Aug 18.

Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA.

Tufted angioma (TA) is a rare vascular tumor characterized by histologic tufts of proliferating capillaries that occurs in infancy or early childhood, with a poorly understood pathogenesis. Though benign, TA can be associated with the Kasabach-Merritt phenomenon (KMP), a life-threatening consumptive coagulopathy and thrombocytopenia. Here, we explored the genetic mechanism underlying a case of TA associated with KMP via targeted sequencing of laser capture micro-dissected lesion and blood DNA, and identified a somatic, activating GNA14 mutation specific to the tumor. Read More

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http://dx.doi.org/10.1111/pde.13979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039697PMC
November 2019
2 Reads

A retrospective study: Clinicopathological and immunohistochemical analysis of 54 cases of tufted angioma.

Indian J Dermatol Venereol Leprol 2020 Jan-Feb;86(1):24-32

Department of Dermatology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi Province, China.

Background: Tufted angioma is a rare benign lesion with vascular proliferation.

Aim: To retrospectively analyze the clinicopathological manifestations and immunohistochemical features of tufted angioma.

Methods: Clinical and histopathological features of tufted angioma (n = 54) were evaluated and analyzed retrospectively in the Department of Dermatology, Xijing Hospital from 2003 to 2014. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_777_18DOI Listing
August 2019
4 Reads

Tacrolimus ointment for the treatment of superficial kaposiform hemangioendothelioma and tufted angioma.

J Dermatol 2019 Oct 2;46(10):898-901. Epub 2019 Aug 2.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) are rare infiltrative vascular tumors. Currently, no standard treatment regimens exist for KHE/TA. The purpose of our study was to evaluate the efficacy and safety of topical application of tacrolimus for superficial KHE/TA. Read More

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http://dx.doi.org/10.1111/1346-8138.15031DOI Listing
October 2019
1 Read

Ultrasonography and magnetic resonance imaging features of kaposiform hemangioendothelioma and tufted angioma.

J Dermatol 2019 Oct 2;46(10):835-842. Epub 2019 Aug 2.

Department of, Ultrasound, School of Medicine, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) primarily occurring in infants are difficult to distinguish. This study evaluated ultrasonography (US) and magnetic resonance imaging (MRI) features of KHE and TA. Pathologically proven TA (n = 21) and KHE (n = 40 [11 KHE + Kasabach-Merritt phenomenon [KMP]]) occurring between January 2015 and December 2017 were reviewed. Read More

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http://dx.doi.org/10.1111/1346-8138.15025DOI Listing
October 2019
3 Reads

Topical timolol maleate for treatment of tufted angioma.

J Dermatol 2019 Nov 27;46(11):e402-e403. Epub 2019 Jun 27.

Department of Dermatology, Beijing Children's Hospital, Capital Medical University (National Center for Children's Health, China), Beijing, China.

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http://dx.doi.org/10.1111/1346-8138.14984DOI Listing
November 2019
7 Reads
2.354 Impact Factor

Low dose sirolimus treatment for refractory tufted angioma and congenital kaposiform hemangioendothelioma, both with Kasabach-Merritt phenomenon.

Pediatr Blood Cancer 2019 08 14;66(8):e27810. Epub 2019 May 14.

Dermatology Service, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.

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http://dx.doi.org/10.1002/pbc.27810DOI Listing
August 2019
2 Reads

Pediatric facial kaposiform hemangioendothelioma: a case report and review of the literature.

J Surg Case Rep 2019 Apr 27;2019(4):rjz113. Epub 2019 Apr 27.

Department of Otolaryngology-Head and Neck Surgery, Wexner Medical Center at Ohio State University, Columbus, OH, USA.

Cutaneous kaposiform hemangioendothelioma (KHE) and tufted angioma (TA) are vascular tumors that are often misdiagnosed. Treatment urgency and type varies depending on which tumor-type is diagnosed, because of the differing rates of progression to Kasabach-Merritt phenomenon. An 11-month-old male presented with a facial mass and biopsy results favoring a diagnosis of TA. Read More

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https://academic.oup.com/jscr/article/doi/10.1093/jscr/rjz11
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http://dx.doi.org/10.1093/jscr/rjz113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486652PMC
April 2019
21 Reads

Surgical excision of a tufted angioma of the hand in an adult-a rare case report with a review of literature.

AME Case Rep 2019 14;3. Epub 2019 Mar 14.

Department of General and Thoracic Surgery, General and Thoracic Surgery Unit, S. Anna Hospital, University of Ferrara, Ferrara, Italy.

Tufted Angiomas, also known as angioblastomas/Angioblastoma of Nagakawa, are rare vascular neoplasms of both sexes localised to the skin and subcutaneous tissues with the upper trunk and neck being the most common sites. They are more common in children but a few cases in juveniles and adults have been reported. Typically, Tufted Angioma remains stable or can show rarely a spontaneous regression. Read More

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http://dx.doi.org/10.21037/acr.2019.02.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458349PMC
March 2019
8 Reads

Indurated Dusky Red Swelling on the Forearm of an Infant: Tufted Angioma.

Indian J Dermatol 2019 Mar-Apr;64(2):146-148

Department of Pathology, University College of Medical Sciences and GTB Hospital (University of Delhi), New Delhi, India.

Tufted angioma (TA) is a rare benign vascular tumor that may be congenital or acquired and generally presents as an asymptomatic or painful solitary erythematous to violaceous poorly defined plaque. Hyperhidrosis and hypertrichosis may be associated. The lesions have tendency to resolve spontaneously, in majority, within 2 years of disease onset. Read More

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http://dx.doi.org/10.4103/ijd.IJD_468_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440174PMC
April 2019
9 Reads

Tufted-angioma-like lesion associated with vascular endothelial growth factor and interleukin-6 in TAFRO syndrome: Is it a common histological feature of multicentric Castleman disease/POEMS syndrome?

J Cutan Pathol 2019 Apr 6;46(4):280-284. Epub 2019 Feb 6.

Department of General Medicine, Tenri Hospital, Nara, Japan.

The histology of skin lesions of TAFRO (thrombocytopenia, anasarca, reticulin fibrosis/renal failure, and organomegaly) syndrome has rarely been reported. We report herein two cases of TAFRO syndrome with characteristic vascular skin lesions. The lesions resembled a tufted angioma, although those of case 1 partially resembled a glomeruloid hemangioma, which was known as a specific lesion in POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes), a variant of multicentric Castleman disease (MCD). Read More

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http://dx.doi.org/10.1111/cup.13415DOI Listing
April 2019
7 Reads

Comparison of Corticosteroid and Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma: A Systematic Review and Meta-Analysis.

Eur J Pediatr Surg 2019 Oct 29;29(5):401-407. Epub 2018 Oct 29.

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, People's Republic of China.

Objective:  To evaluate the outcome and safety of corticosteroids and vincristine (VCR) in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA).

Materials And Methods:  Clinical studies involving corticosteroids and VCR therapies in treating KHE/TA were identified by using PubMed, Cochrane Library, OVID, EBSCO, CNKI, VIP, and Wanfang databases from their establishment date to December 2017. Randomized controlled trials, case-control, or case series with more than five cases were included. Read More

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http://dx.doi.org/10.1055/s-0038-1673708DOI Listing
October 2019
39 Reads

Tufted angioma arising at the site of hepatitis B vaccination: A case report.

Turk J Pediatr 2018 ;60(2):188-190

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F. Tufted angioma arising at the site of hepatitis B vaccination: A case report. Turk J Pediatr 2018; 60: 188-190. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2018.02.011DOI Listing
May 2019
50 Reads

Congenital tufted angioma: A multicenter retrospective study of 30 cases.

Pediatr Dermatol 2018 Nov 15;35(6):808-816. Epub 2018 Oct 15.

Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

Background: Recent reports indicate that tufted angioma is a rare vascular neoplasm that manifests more frequently at birth than previously thought. Few studies specifically address congenital presentation.

Objectives: We analyzed the clinicopathological characteristics, clinical course, and treatment of congenital tufted angioma (cTA) and evaluated variables that were indicative of problematic lesions. Read More

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http://doi.wiley.com/10.1111/pde.13683
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http://dx.doi.org/10.1111/pde.13683DOI Listing
November 2018
48 Reads

A rapidly growing violaceous tumor in a neonate.

JAAD Case Rep 2018 Oct 3;4(9):893-895. Epub 2018 Oct 3.

Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia.

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http://dx.doi.org/10.1016/j.jdcr.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172438PMC
October 2018
7 Reads

A Case Report on Acquired Tufted Angioma with Severe Pain after Healed Herpes Zoster.

Chin Med J (Engl) 2018 10;131(19):2378-2379

Department of Dermatology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.

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http://dx.doi.org/10.4103/0366-6999.241796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166449PMC
October 2018
9 Reads

Development of Kasabach-Merritt phenomenon following vaccination: More than a coincidence?

J Dermatol 2018 Oct 17;45(10):1203-1206. Epub 2018 Aug 17.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Kasabach-Merritt phenomenon (KMP) occurred uniquely in patients with kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). We report the clinical characteristics of two patients with KHE involving the right upper arm. The patients demonstrated rapid enlargement of the lesion with severe KMP shortly after vaccination. Read More

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http://doi.wiley.com/10.1111/1346-8138.14598
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http://dx.doi.org/10.1111/1346-8138.14598DOI Listing
October 2018
55 Reads

Retrospective study on the outcomes of infantile tufted angioma complicated by Kasabach-Merritt Phenomenon.

Clin Chim Acta 2018 Nov 7;486:199-204. Epub 2018 Aug 7.

Department of Hemangioma and Vascular Malformation Surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, 7 Weiwu Road, Zhengzhou 450003, China. Electronic address:

Objective: To analyze the clinical characteristics and treatment of pediatric tufted angiomas(TA)complicated by Kasabach-Merritt Phenomenon (KMP).

Method: A retrospective analysis was conducted on the clinical data and follow-up data of 13 patients diagnosed with TA complicated by KMP. Five male and 8 female patients with an average age of 5. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183039
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http://dx.doi.org/10.1016/j.cca.2018.07.044DOI Listing
November 2018
38 Reads

Topical rapamycin (sirolimus) for the treatment of uncomplicated tufted angiomas in two children and review of the literature.

Pediatr Dermatol 2018 Sep 17;35(5):e286-e290. Epub 2018 Jul 17.

Department of Dermatology, University of British Columbia, Vancouver, BC, Canada.

The mTOR inhibitor rapamycin is used systemically for the treatment of vascular lesions. We report the first use of topical rapamycin for the successful treatment of two cases of tufted angioma. The evidence for the use of topical rapamycin in other dermatologic conditions is summarized to aid in clinical decision making on preparations and anticipated side effects. Read More

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http://dx.doi.org/10.1111/pde.13596DOI Listing
September 2018
5 Reads

Sirolimus as initial therapy for kaposiform hemangioendothelioma and tufted angioma.

Pediatr Dermatol 2018 Sep 12;35(5):635-638. Epub 2018 Jul 12.

Department of Pediatric Surgery, Second Affiliated Hospital, Medical College of Xi'an, JiaoTong University, Xi'an, China.

Background: Sirolimus has been used to manage various complex vascular anomalies. Kaposiform hemangioendothelioma and tufted angioma may develop Kasabach-Merritt phenomenon in infancy.

Methods: We retrospectively reviewed the clinical and laboratory data of eight patients with kaposiform hemangioendothelioma and tufted angioma who were initially treated using oral sirolimus in our center, including six with Kasabach-Merritt phenomenon. Read More

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http://dx.doi.org/10.1111/pde.13600DOI Listing
September 2018
16 Reads

Frequent GNAQ and GNA14 Mutations in Hepatic Small Vessel Neoplasm.

Am J Surg Pathol 2018 09;42(9):1201-1207

Department of Pathology, University of California, San Francisco, San Francisco, CA.

Hepatic small vessel neoplasm (HSVN) is a recently described infiltrative vascular neoplasm of the liver, composed of small vessels. Although the infiltrative nature can mimic angiosarcoma, HSVN are thought to be benign or low-grade neoplasms because they lack cytologic atypia and increased proliferation. To characterize the molecular pathogenesis of HSVN, we performed both targeted panel sequencing and exome sequencing on 18 benign or low-grade vascular neoplasms in the liver including 8 HSVN, 6 classic cavernous hemangioma (CH), and 4 variant lesions (VL) with overlapping features between HSVN and CH. Read More

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http://dx.doi.org/10.1097/PAS.0000000000001110DOI Listing
September 2018
13 Reads

Acral nodule as a form of atypical presentation of a tufted angioma in adulthood.

Int J Dermatol 2018 08 5;57(8):e54-e55. Epub 2018 Jun 5.

Department of Dermatology, Hospital Arnau de Vilanova, Valencia, Spain.

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http://doi.wiley.com/10.1111/ijd.14077
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http://dx.doi.org/10.1111/ijd.14077DOI Listing
August 2018
8 Reads

Vascular Tumors in Infants: Case Report and Review of Clinical, Histopathologic, and Immunohistochemical Characteristics of Infantile Hemangioma, Pyogenic Granuloma, Noninvoluting Congenital Hemangioma, Tufted Angioma, and Kaposiform Hemangioendothelioma.

Am J Dermatopathol 2018 Apr;40(4):231-239

Professor, Department of Dermatology, Mayo Clinic, Rochester, MN.

Vascular tumors in infants present a diagnostic and treatment dilemma for both clinicians and pathologists. Infantile hemangioma, the most common vascular tumor in infants, can be confused for other less common vascular tumors in infants. Correct and timely diagnosis is important, as some vascular tumors can be associated with life-threatening coagulopathy. Read More

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http://Insights.ovid.com/crossref?an=00000372-201804000-0000
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http://dx.doi.org/10.1097/DAD.0000000000000983DOI Listing
April 2018
37 Reads
1.426 Impact Factor

Tufted angioma of the finger: A case of an uncommon location with unique dermoscopic features.

J Dermatol 2018 Aug 6;45(8):e236-e237. Epub 2018 Mar 6.

Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://doi.wiley.com/10.1111/1346-8138.14279
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http://dx.doi.org/10.1111/1346-8138.14279DOI Listing
August 2018
43 Reads

Immunoreactivity of Wilms tumor 1 (WT1) as an additional evidence supporting hemangiomatous rather than inflammatory origin in the etiopathogenesis of angiolymphoid hyperplasia with eosinophilia.

Dermatol Pract Concept 2018 Jan 31;8(1):28-32. Epub 2018 Jan 31.

Department of Dermatology Acibadem University School of Medicine, Istanbul, Turkey.

Background: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare vascular proliferative disorder mainly located in the periauricular region. The etiopathogenesis of ALHE is unknown, and it is still controversial as to whether the entity represents a benign vascular neoplasm or an inflammatory process.

Aim: Recently, the intracytoplasmic staining pattern of Wilms tumor 1 (WT1) on immunohistochemistry has highlighted true vascular neoplasms, such as microvenular hemangioma, tufted angioma, and spindle cell hemangioma, which has made it helpful to distinguish ALHE from vascular malformations, as there is a negative staining pattern in the other entities. Read More

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http://dx.doi.org/10.5826/dpc.0801a06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808368PMC
January 2018
15 Reads

Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus.

J Dermatol 2018 May 21;45(5):580-583. Epub 2018 Jan 21.

Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China.

Vascular tumors associated with Kasabach-Merritt phenomenon (KMP) are life-threatening and the mortality is as high as 10-30%. Steroids are considered the primary choice for drug therapy. However, there are many steroid-resistant cases. Read More

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http://doi.wiley.com/10.1111/1346-8138.14231
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http://dx.doi.org/10.1111/1346-8138.14231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947617PMC
May 2018
34 Reads

Congenital Vascular Tumors.

Otolaryngol Clin North Am 2018 Feb;51(1):89-97

Department of Plastic and Oral Surgery, Vascular Anomalies Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue Boston, MA, 02115, USA. Electronic address:

Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, congestive heart failure, and death. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00306665173015
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http://dx.doi.org/10.1016/j.otc.2017.09.008DOI Listing
February 2018
14 Reads

Tufted angioma.

An Bras Dermatol 2017 Sep-Oct;92(5):742-743

Dermatologic Surgery Service - Fundação Alfredo da Matta (FUAM) - Manaus (AM), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20175896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674719PMC
September 2018
11 Reads

Episode of Kasabach-Merritt phenomenon following Japanese encephalitis vaccination: Case report.

Vaccine 2017 12 16;35(48 Pt B):6594-6597. Epub 2017 Oct 16.

Department of Cardiac Surgery, The Children's Hospital of Zhejiang University School of Medicine, Zhejiang, China. Electronic address:

Kasabach-Merritt phenomenon (KMP) is a rare potentially life-threatening consumptive coagulopathy characterized by thrombocytopenia and hypofibrinogenemia occurring associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). A 10-month old male infant, diagnosed with KHE on his left leg, underwent a rapid increase of the lesion and severe thrombocytopenia, one day after the first dose of inactivated Japanese encephalitis (JE) vaccination. The episode of KMP was treated successfully by steroid. Read More

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http://dx.doi.org/10.1016/j.vaccine.2017.08.011DOI Listing
December 2017
14 Reads

Topical Rapamycin: An Additional Therapeutic Option for Tufted Angioma in Adults.

Actas Dermosifiliogr 2018 Mar 13;109(2):192-194. Epub 2017 Aug 13.

Servicio de Dermatología, Hospital Universitario Son Espases, Palma de Mallorca, España.

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https://linkinghub.elsevier.com/retrieve/pii/S00017310173038
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http://dx.doi.org/10.1016/j.ad.2017.04.026DOI Listing
March 2018
11 Reads

Clinical and sonographic features of pediatric soft-tissue vascular anomalies part 1: classification, sonographic approach and vascular tumors.

Pediatr Radiol 2017 Aug 4;47(9):1184-1195. Epub 2017 Aug 4.

Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Toronto, ON, M5G 1X8, Canada.

Sonography can be used in the management of pediatric soft-tissue vascular anomalies for diagnosing, for assessing lesion extent and for evaluating complications and response to therapy. The sonographic technique includes a combination of gray-scale imaging with color and spectral Doppler techniques. However the interpretation of the sonographic findings requires correlation with the clinical findings, some of which can be easily obtained at the time of scanning. Read More

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http://dx.doi.org/10.1007/s00247-017-3885-yDOI Listing
August 2017
50 Reads

[Tufted angiomas of the head and neck. German version].

HNO 2017 Dec;65(12):981-986

Klinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

Background: Tufted angiomas (TAs) are uncommon benign vascular tumors mostly located cutaneously or subcutaneously in the skin of the neck and upper trunk, which appear during childhood and grow slowly. TAs are a variant of lobular capillary hemangiomas. This is the first study to provide an overview of the current literature in combination with the authors' own clinical experience on this rare entity in the head and neck area with non-dermatological localization. Read More

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http://dx.doi.org/10.1007/s00106-017-0379-zDOI Listing
December 2017
3 Reads

Tufted angiomas of the head and neck.

HNO 2018 Jan;66(Suppl 1):1-6

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: Tufted angiomas (TAs) are uncommon benign vascular tumors mostly located cutaneously or subcutaneously in the skin of the neck and upper trunk, which appear during childhood and grow slowly. TAs are a variant of lobular capillary hemangiomas. This is the first study to provide an overview of the current literature in combination with the authors' own clinical experience on this rare entity in the head and neck area with non-dermatological localization. Read More

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http://dx.doi.org/10.1007/s00106-017-0375-3DOI Listing
January 2018
4 Reads

Successful treatment of tufted angioma with low-dose electron beam radiation therapy: Report of two cases.

J Dermatol 2017 Oct 17;44(10):e262-e263. Epub 2017 Jun 17.

Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, Yonago, Japan.

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http://doi.wiley.com/10.1111/1346-8138.13936
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http://dx.doi.org/10.1111/1346-8138.13936DOI Listing
October 2017
26 Reads

Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report.

Oncol Lett 2017 Jun 20;13(6):4887-4891. Epub 2017 Apr 20.

Department of Reconstructive Plastic Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China.

Kasabach-Merritt syndrome (KMS) is a rare type of vascular tumor associated with a severely decreased platelet count. No standard guidelines for the treatment of the disease have been established so far. In the present study, a 1-year-old pediatric patient with KMS arising from tufted angioma was successfully and variously treated with steroids, vincristine, surgery and propranolol for 18 months. Read More

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http://dx.doi.org/10.3892/ol.2017.6064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453004PMC
June 2017
60 Reads

Kasabach-Merritt Phenomenon: Classic Presentation and Management Options.

Clin Med Insights Blood Disord 2017 16;10:1179545X17699849. Epub 2017 Mar 16.

Department of Pediatrics, Baylor College of Medicine, Vascular Anomalies Center at Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Houston, TX, USA.

Kasabach-Merritt phenomenon (KMP) is a rare consumptive coagulopathy associated with specific vascular tumors, kaposiform hemangioendothelioma, and tufted angioma. Kasabach-Merritt phenomenon, characterized by profound thrombocytopenia, hypofibrinogenemia, elevated fibrin split products, and rapid tumor growth, can be life-threatening. Severe symptomatic anemia may also be present. Read More

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http://dx.doi.org/10.1177/1179545X17699849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428202PMC
March 2017
12 Reads

Cytotoxic-mediated spontaneous regression of eruptive tufted angioma in a teenage girl.

Authors:
C Tomasini

J Eur Acad Dermatol Venereol 2017 Dec 7;31(12):e522-e523. Epub 2017 Jul 7.

Department of Medical Sciences and Infectious Disease Dermatologic Clinic, IRCCS Policlinico San Matteo, 27100, Pavia, Italy.

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http://doi.wiley.com/10.1111/jdv.14382
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http://dx.doi.org/10.1111/jdv.14382DOI Listing
December 2017
6 Reads

Tufted angioma associated with hyperplasia of eccrine sweat glands.

Clin Exp Dermatol 2017 Jul 22;42(5):548-550. Epub 2017 May 22.

Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, Niigata, 951-8510, Japan.

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http://dx.doi.org/10.1111/ced.13122DOI Listing
July 2017
10 Reads

Sirolimus therapy for children with problematic kaposiform haemangioendothelioma and tufted angioma.

Br J Dermatol 2017 12 22;177(6):e344-e346. Epub 2017 Nov 22.

Department of Dermatology, Great Ormond Street Hospital For Children NHS Foundation Trust, London, U.K.

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http://doi.wiley.com/10.1111/bjd.15640
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http://dx.doi.org/10.1111/bjd.15640DOI Listing
December 2017
21 Reads

Histopathology of Spindle Cell Vascular Tumors.

Surg Pathol Clin 2017 Jun 31;10(2):345-366. Epub 2017 Mar 31.

Department of Pathology, Cleveland Clinic, 9500 Euclid Avenue, L25, Cleveland, OH 44195, USA. Electronic address:

Vascular tumors with a spindled morphology represent a diagnostic challenge in soft tissue pathology. It may be difficult to distinguish certain benign entities in this category from spindled vascular tumors of intermediate malignancy or even spindled variants of angiosarcoma. This article focuses on vascular tumors characterized by a predominantly spindled morphology, including spindle cell hemangioma, acquired tufted angioma (angioblastoma of Nakagawa), kaposiform hemangioendothelioma, Kaposi sarcoma, and spindle cell variants of angiosarcoma. Read More

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http://dx.doi.org/10.1016/j.path.2017.01.006DOI Listing
June 2017
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Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.

Pathology 2017 Jun 21;49(4):356-362. Epub 2017 Apr 21.

Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.

Kaposiform haemangioendothelioma (KHE) is a rare, locally aggressive/borderline vascular tumour primarily seen in neonates and children. KHE is occasionally associated with Kasabach-Merritt phenomenon and tends to have a poor clinical prognosis. While the histological features of tufted angiomas and KHE overlap, some believe tufted angiomas are a milder, benign, more localised counterpart of KHE. Read More

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http://dx.doi.org/10.1016/j.pathol.2017.03.001DOI Listing
June 2017
9 Reads
2.190 Impact Factor

Intracranial intraaxial cerebral tufted angioma: case report.

J Neurosurg 2018 02 24;128(2):524-529. Epub 2017 Feb 24.

Departments of1Neurological Surgery.

Tufted angioma (TA) is a rare, slow-growing, vascular lesion that commonly presents as a solitary macule, papule, or nodule arising in the soft tissues of the torso, extremities, and head and neck in children and young adults. Adult-onset cases have been infrequently reported. While typically benign, TAs may be locally aggressive. Read More

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http://dx.doi.org/10.3171/2016.10.JNS162207DOI Listing
February 2018
37 Reads