212 results match your criteria Tufted Angioma


Tufted-angioma-like lesion associated with vascular endothelial growth factor and interleukin-6 in TAFRO syndrome: Is it a common histological feature of multicentric Castleman disease/POEMS syndrome?

J Cutan Pathol 2019 Jan 10. Epub 2019 Jan 10.

Department of General Medicine, Tenri Hospital, Nara, Japan.

The histology of skin lesions of TAFRO (thrombocytopenia, anasarca, reticulin fibrosis/renal failure, and organomegaly) syndrome has rarely been reported. We report herein two cases of TAFRO syndrome with characteristic vascular skin lesions. The lesions resembled a tufted angioma, although those of case 1 partially resembled a glomeruloid hemangioma, which was known as a specific lesion in POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes), a variant of multicentric Castleman disease (MCD). Read More

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http://dx.doi.org/10.1111/cup.13415DOI Listing
January 2019
1 Read

Comparison of Corticosteroid and Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma: A Systematic Review and Meta-Analysis.

Eur J Pediatr Surg 2018 Oct 29. Epub 2018 Oct 29.

Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, People's Republic of China.

Objective:  To evaluate the outcome and safety of corticosteroids and vincristine (VCR) in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA).

Materials And Methods:  Clinical studies involving corticosteroids and VCR therapies in treating KHE/TA were identified by using PubMed, Cochrane Library, OVID, EBSCO, CNKI, VIP, and Wanfang databases from their establishment date to December 2017. Randomized controlled trials, case-control, or case series with more than five cases were included. Read More

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http://dx.doi.org/10.1055/s-0038-1673708DOI Listing
October 2018
10 Reads

Tufted angioma arising at the site of hepatitis B vaccination: A case report.

Turk J Pediatr 2018 ;60(2):188-190

Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Sepaskhah M, Hajizadeh J, Sari-Aslani F, Jowkar F. Tufted angioma arising at the site of hepatitis B vaccination: A case report. Turk J Pediatr 2018; 60: 188-190. Read More

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http://www.turkishjournalpediatrics.org/doi.php?doi=10.24953
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http://dx.doi.org/10.24953/turkjped.2018.02.011DOI Listing
January 2018
18 Reads

Congenital tufted angioma: A multicenter retrospective study of 30 cases.

Pediatr Dermatol 2018 Nov 15;35(6):808-816. Epub 2018 Oct 15.

Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.

Background: Recent reports indicate that tufted angioma is a rare vascular neoplasm that manifests more frequently at birth than previously thought. Few studies specifically address congenital presentation.

Objectives: We analyzed the clinicopathological characteristics, clinical course, and treatment of congenital tufted angioma (cTA) and evaluated variables that were indicative of problematic lesions. Read More

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http://doi.wiley.com/10.1111/pde.13683
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http://dx.doi.org/10.1111/pde.13683DOI Listing
November 2018
12 Reads

A rapidly growing violaceous tumor in a neonate.

JAAD Case Rep 2018 Oct 3;4(9):893-895. Epub 2018 Oct 3.

Division of Dermatology, Medical College of Georgia at Augusta University, Augusta, Georgia.

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http://dx.doi.org/10.1016/j.jdcr.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172438PMC
October 2018
1 Read

A Case Report on Acquired Tufted Angioma with Severe Pain after Healed Herpes Zoster.

Chin Med J (Engl) 2018 Oct;131(19):2378-2379

Department of Dermatology, Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu 212001, China.

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http://dx.doi.org/10.4103/0366-6999.241796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166449PMC
October 2018

Development of Kasabach-Merritt phenomenon following vaccination: More than a coincidence?

J Dermatol 2018 Oct 17;45(10):1203-1206. Epub 2018 Aug 17.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Kasabach-Merritt phenomenon (KMP) occurred uniquely in patients with kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). We report the clinical characteristics of two patients with KHE involving the right upper arm. The patients demonstrated rapid enlargement of the lesion with severe KMP shortly after vaccination. Read More

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http://doi.wiley.com/10.1111/1346-8138.14598
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http://dx.doi.org/10.1111/1346-8138.14598DOI Listing
October 2018
21 Reads

Retrospective study on the outcomes of infantile tufted angioma complicated by Kasabach-Merritt Phenomenon.

Clin Chim Acta 2018 Nov 7;486:199-204. Epub 2018 Aug 7.

Department of Hemangioma and Vascular Malformation Surgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, 7 Weiwu Road, Zhengzhou 450003, China. Electronic address:

Objective: To analyze the clinical characteristics and treatment of pediatric tufted angiomas(TA)complicated by Kasabach-Merritt Phenomenon (KMP).

Method: A retrospective analysis was conducted on the clinical data and follow-up data of 13 patients diagnosed with TA complicated by KMP. Five male and 8 female patients with an average age of 5. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183039
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http://dx.doi.org/10.1016/j.cca.2018.07.044DOI Listing
November 2018
20 Reads

Topical rapamycin (sirolimus) for the treatment of uncomplicated tufted angiomas in two children and review of the literature.

Pediatr Dermatol 2018 Sep 17;35(5):e286-e290. Epub 2018 Jul 17.

Department of Dermatology, University of British Columbia, Vancouver, BC, Canada.

The mTOR inhibitor rapamycin is used systemically for the treatment of vascular lesions. We report the first use of topical rapamycin for the successful treatment of two cases of tufted angioma. The evidence for the use of topical rapamycin in other dermatologic conditions is summarized to aid in clinical decision making on preparations and anticipated side effects. Read More

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http://dx.doi.org/10.1111/pde.13596DOI Listing
September 2018

Sirolimus as initial therapy for kaposiform hemangioendothelioma and tufted angioma.

Pediatr Dermatol 2018 Sep 12;35(5):635-638. Epub 2018 Jul 12.

Department of Pediatric Surgery, Second Affiliated Hospital, Medical College of Xi'an, JiaoTong University, Xi'an, China.

Background: Sirolimus has been used to manage various complex vascular anomalies. Kaposiform hemangioendothelioma and tufted angioma may develop Kasabach-Merritt phenomenon in infancy.

Methods: We retrospectively reviewed the clinical and laboratory data of eight patients with kaposiform hemangioendothelioma and tufted angioma who were initially treated using oral sirolimus in our center, including six with Kasabach-Merritt phenomenon. Read More

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http://dx.doi.org/10.1111/pde.13600DOI Listing
September 2018
4 Reads

Frequent GNAQ and GNA14 Mutations in Hepatic Small Vessel Neoplasm.

Am J Surg Pathol 2018 Sep;42(9):1201-1207

Department of Pathology, University of California, San Francisco, San Francisco, CA.

Hepatic small vessel neoplasm (HSVN) is a recently described infiltrative vascular neoplasm of the liver, composed of small vessels. Although the infiltrative nature can mimic angiosarcoma, HSVN are thought to be benign or low-grade neoplasms because they lack cytologic atypia and increased proliferation. To characterize the molecular pathogenesis of HSVN, we performed both targeted panel sequencing and exome sequencing on 18 benign or low-grade vascular neoplasms in the liver including 8 HSVN, 6 classic cavernous hemangioma (CH), and 4 variant lesions (VL) with overlapping features between HSVN and CH. Read More

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http://dx.doi.org/10.1097/PAS.0000000000001110DOI Listing
September 2018
3 Reads

Acral nodule as a form of atypical presentation of a tufted angioma in adulthood.

Int J Dermatol 2018 08 5;57(8):e54-e55. Epub 2018 Jun 5.

Department of Dermatology, Hospital Arnau de Vilanova, Valencia, Spain.

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http://doi.wiley.com/10.1111/ijd.14077
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http://dx.doi.org/10.1111/ijd.14077DOI Listing
August 2018
2 Reads

Vascular Tumors in Infants: Case Report and Review of Clinical, Histopathologic, and Immunohistochemical Characteristics of Infantile Hemangioma, Pyogenic Granuloma, Noninvoluting Congenital Hemangioma, Tufted Angioma, and Kaposiform Hemangioendothelioma.

Am J Dermatopathol 2018 Apr;40(4):231-239

Professor, Department of Dermatology, Mayo Clinic, Rochester, MN.

Vascular tumors in infants present a diagnostic and treatment dilemma for both clinicians and pathologists. Infantile hemangioma, the most common vascular tumor in infants, can be confused for other less common vascular tumors in infants. Correct and timely diagnosis is important, as some vascular tumors can be associated with life-threatening coagulopathy. Read More

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http://Insights.ovid.com/crossref?an=00000372-201804000-0000
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http://dx.doi.org/10.1097/DAD.0000000000000983DOI Listing
April 2018
17 Reads

Tufted angioma of the finger: A case of an uncommon location with unique dermoscopic features.

J Dermatol 2018 Aug 6;45(8):e236-e237. Epub 2018 Mar 6.

Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://doi.wiley.com/10.1111/1346-8138.14279
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http://dx.doi.org/10.1111/1346-8138.14279DOI Listing
August 2018
18 Reads

Immunoreactivity of Wilms tumor 1 (WT1) as an additional evidence supporting hemangiomatous rather than inflammatory origin in the etiopathogenesis of angiolymphoid hyperplasia with eosinophilia.

Dermatol Pract Concept 2018 Jan 31;8(1):28-32. Epub 2018 Jan 31.

Department of Dermatology Acibadem University School of Medicine, Istanbul, Turkey.

Background: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare vascular proliferative disorder mainly located in the periauricular region. The etiopathogenesis of ALHE is unknown, and it is still controversial as to whether the entity represents a benign vascular neoplasm or an inflammatory process.

Aim: Recently, the intracytoplasmic staining pattern of Wilms tumor 1 (WT1) on immunohistochemistry has highlighted true vascular neoplasms, such as microvenular hemangioma, tufted angioma, and spindle cell hemangioma, which has made it helpful to distinguish ALHE from vascular malformations, as there is a negative staining pattern in the other entities. Read More

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http://dx.doi.org/10.5826/dpc.0801a06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808368PMC
January 2018
5 Reads

Successful management of steroid-resistant vascular tumors associated with the Kasabach-Merritt phenomenon using sirolimus.

J Dermatol 2018 May 21;45(5):580-583. Epub 2018 Jan 21.

Guangzhou Women and Children's Medical Center, Guangzhou Medical University, China.

Vascular tumors associated with Kasabach-Merritt phenomenon (KMP) are life-threatening and the mortality is as high as 10-30%. Steroids are considered the primary choice for drug therapy. However, there are many steroid-resistant cases. Read More

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http://doi.wiley.com/10.1111/1346-8138.14231
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http://dx.doi.org/10.1111/1346-8138.14231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947617PMC
May 2018
11 Reads

Congenital Vascular Tumors.

Otolaryngol Clin North Am 2018 Feb;51(1):89-97

Department of Plastic and Oral Surgery, Vascular Anomalies Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue Boston, MA, 02115, USA. Electronic address:

Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, congestive heart failure, and death. Read More

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http://dx.doi.org/10.1016/j.otc.2017.09.008DOI Listing
February 2018
7 Reads

Tufted angioma.

An Bras Dermatol 2017 Sep-Oct;92(5):742-743

Dermatologic Surgery Service - Fundação Alfredo da Matta (FUAM) - Manaus (AM), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20175896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674719PMC
September 2018
8 Reads

Episode of Kasabach-Merritt phenomenon following Japanese encephalitis vaccination: Case report.

Vaccine 2017 12 16;35(48 Pt B):6594-6597. Epub 2017 Oct 16.

Department of Cardiac Surgery, The Children's Hospital of Zhejiang University School of Medicine, Zhejiang, China. Electronic address:

Kasabach-Merritt phenomenon (KMP) is a rare potentially life-threatening consumptive coagulopathy characterized by thrombocytopenia and hypofibrinogenemia occurring associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). A 10-month old male infant, diagnosed with KHE on his left leg, underwent a rapid increase of the lesion and severe thrombocytopenia, one day after the first dose of inactivated Japanese encephalitis (JE) vaccination. The episode of KMP was treated successfully by steroid. Read More

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http://dx.doi.org/10.1016/j.vaccine.2017.08.011DOI Listing
December 2017
5 Reads

Topical Rapamycin: An Additional Therapeutic Option for Tufted Angioma in Adults.

Actas Dermosifiliogr 2018 Mar 13;109(2):192-194. Epub 2017 Aug 13.

Servicio de Dermatología, Hospital Universitario Son Espases, Palma de Mallorca, España.

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https://linkinghub.elsevier.com/retrieve/pii/S00017310173038
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http://dx.doi.org/10.1016/j.ad.2017.04.026DOI Listing
March 2018
5 Reads

Clinical and sonographic features of pediatric soft-tissue vascular anomalies part 1: classification, sonographic approach and vascular tumors.

Pediatr Radiol 2017 Aug 4;47(9):1184-1195. Epub 2017 Aug 4.

Department of Diagnostic Imaging, The Hospital for Sick Children, 555 University Ave., Toronto, ON, M5G 1X8, Canada.

Sonography can be used in the management of pediatric soft-tissue vascular anomalies for diagnosing, for assessing lesion extent and for evaluating complications and response to therapy. The sonographic technique includes a combination of gray-scale imaging with color and spectral Doppler techniques. However the interpretation of the sonographic findings requires correlation with the clinical findings, some of which can be easily obtained at the time of scanning. Read More

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http://dx.doi.org/10.1007/s00247-017-3885-yDOI Listing
August 2017
20 Reads

Successful treatment of tufted angioma with low-dose electron beam radiation therapy: Report of two cases.

J Dermatol 2017 Oct 17;44(10):e262-e263. Epub 2017 Jun 17.

Division of Dermatology, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, Tottori University, Yonago, Japan.

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http://doi.wiley.com/10.1111/1346-8138.13936
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http://dx.doi.org/10.1111/1346-8138.13936DOI Listing
October 2017
13 Reads

Multimodal treatment of Kasabach-Merritt syndrome arising from tufted angioma: A case report.

Oncol Lett 2017 Jun 20;13(6):4887-4891. Epub 2017 Apr 20.

Department of Reconstructive Plastic Surgery, The Children's Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310003, P.R. China.

Kasabach-Merritt syndrome (KMS) is a rare type of vascular tumor associated with a severely decreased platelet count. No standard guidelines for the treatment of the disease have been established so far. In the present study, a 1-year-old pediatric patient with KMS arising from tufted angioma was successfully and variously treated with steroids, vincristine, surgery and propranolol for 18 months. Read More

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http://dx.doi.org/10.3892/ol.2017.6064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453004PMC
June 2017
26 Reads

Kasabach-Merritt Phenomenon: Classic Presentation and Management Options.

Clin Med Insights Blood Disord 2017 16;10:1179545X17699849. Epub 2017 Mar 16.

Department of Pediatrics, Baylor College of Medicine, Vascular Anomalies Center at Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Houston, TX, USA.

Kasabach-Merritt phenomenon (KMP) is a rare consumptive coagulopathy associated with specific vascular tumors, kaposiform hemangioendothelioma, and tufted angioma. Kasabach-Merritt phenomenon, characterized by profound thrombocytopenia, hypofibrinogenemia, elevated fibrin split products, and rapid tumor growth, can be life-threatening. Severe symptomatic anemia may also be present. Read More

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http://dx.doi.org/10.1177/1179545X17699849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428202PMC
March 2017
9 Reads

Cytotoxic-mediated spontaneous regression of eruptive tufted angioma in a teenage girl.

Authors:
C Tomasini

J Eur Acad Dermatol Venereol 2017 Dec 7;31(12):e522-e523. Epub 2017 Jul 7.

Department of Medical Sciences and Infectious Disease Dermatologic Clinic, IRCCS Policlinico San Matteo, 27100, Pavia, Italy.

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http://doi.wiley.com/10.1111/jdv.14382
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http://dx.doi.org/10.1111/jdv.14382DOI Listing
December 2017
3 Reads

Tufted angioma associated with hyperplasia of eccrine sweat glands.

Clin Exp Dermatol 2017 Jul 22;42(5):548-550. Epub 2017 May 22.

Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata, Niigata, 951-8510, Japan.

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http://dx.doi.org/10.1111/ced.13122DOI Listing
July 2017
4 Reads

Sirolimus therapy for children with problematic kaposiform haemangioendothelioma and tufted angioma.

Br J Dermatol 2017 12 22;177(6):e344-e346. Epub 2017 Nov 22.

Department of Dermatology, Great Ormond Street Hospital For Children NHS Foundation Trust, London, U.K.

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http://doi.wiley.com/10.1111/bjd.15640
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http://dx.doi.org/10.1111/bjd.15640DOI Listing
December 2017
13 Reads

Histopathology of Spindle Cell Vascular Tumors.

Surg Pathol Clin 2017 Jun 31;10(2):345-366. Epub 2017 Mar 31.

Department of Pathology, Cleveland Clinic, 9500 Euclid Avenue, L25, Cleveland, OH 44195, USA. Electronic address:

Vascular tumors with a spindled morphology represent a diagnostic challenge in soft tissue pathology. It may be difficult to distinguish certain benign entities in this category from spindled vascular tumors of intermediate malignancy or even spindled variants of angiosarcoma. This article focuses on vascular tumors characterized by a predominantly spindled morphology, including spindle cell hemangioma, acquired tufted angioma (angioblastoma of Nakagawa), kaposiform hemangioendothelioma, Kaposi sarcoma, and spindle cell variants of angiosarcoma. Read More

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http://dx.doi.org/10.1016/j.path.2017.01.006DOI Listing
June 2017
6 Reads

Kaposiform haemangioendothelioma: a review with emphasis on histological differential diagnosis.

Pathology 2017 Jun 21;49(4):356-362. Epub 2017 Apr 21.

Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.

Kaposiform haemangioendothelioma (KHE) is a rare, locally aggressive/borderline vascular tumour primarily seen in neonates and children. KHE is occasionally associated with Kasabach-Merritt phenomenon and tends to have a poor clinical prognosis. While the histological features of tufted angiomas and KHE overlap, some believe tufted angiomas are a milder, benign, more localised counterpart of KHE. Read More

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http://dx.doi.org/10.1016/j.pathol.2017.03.001DOI Listing
June 2017
4 Reads
2.190 Impact Factor

Intracranial intraaxial cerebral tufted angioma: case report.

J Neurosurg 2018 Feb 24;128(2):524-529. Epub 2017 Feb 24.

Departments of1Neurological Surgery.

Tufted angioma (TA) is a rare, slow-growing, vascular lesion that commonly presents as a solitary macule, papule, or nodule arising in the soft tissues of the torso, extremities, and head and neck in children and young adults. Adult-onset cases have been infrequently reported. While typically benign, TAs may be locally aggressive. Read More

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http://dx.doi.org/10.3171/2016.10.JNS162207DOI Listing
February 2018
21 Reads

Efficiency of an mTOR Inhibitor in Kasabach-Merritt Phenomenon with Indolent Tufted Angioma: A Case Report.

Acta Derm Venereol 2017 Jul;97(7):851-852

Department of Dermatology, Centre Hospitalier Universitaire, FR-25000 Besancon, France.

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http://dx.doi.org/10.2340/00015555-2597DOI Listing
July 2017
13 Reads

An intermediate vascular tumour between kaposiform hemangioendothelioma and tufted angioma with regression of the skin lesion.

Eur J Dermatol 2017 04;27(2):175-176

Department of Dermatology Graduate School of Medicine and Pharmaceutical Sciences University of Toyama Japan.

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http://dx.doi.org/10.1684/ejd.2016.2922DOI Listing
April 2017
8 Reads

Tufted angioma with recurrent Kasabach-Merritt phenomenon.

Indian J Dermatol Venereol Leprol 2018 Jan-Feb;84(1):121

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.4103/0378-6323.193622DOI Listing
November 2018
12 Reads

The clinical spectrum of kaposiform hemangioendothelioma and tufted angioma.

Semin Cutan Med Surg 2016 Sep;35(3):147-52

Department of Pediatrics, Division of Dermatology, Seattle Children's Hospital/University of Washington School of Medicine, Seattle, Washington, USA.

Kasposiform hemoangioendothelioma (KHE) and tufted angioma (TA) are classifed as vascular tumors with locally aggressive and benign growth potential, respectively, within the classification schema proposed by the International Society for the Study of Vascular Anomalies. A unique feature of these vascular tumors is the risk of Kasabach-Merritt phenomenon (KMP), a severe thrombocytopenia with mild to moderate coagulopathy resulting from intralesional platelet trapping. As with many vascular anomalies, accurate description of clinical course, responses to therapy, and long-term outcomes have been hindered by lesion misidentification, imprecise nomenclature, and lack of prospective, randomized clinical trials to assess therapeutic efficacy. Read More

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http://dx.doi.org/10.12788/j.sder.2016.048DOI Listing
September 2016
18 Reads

Tufted Angioma of Eyelid in an Adult - A Case Report.

J Clin Diagn Res 2016 Jun 1;10(6):ED12-3. Epub 2016 Jun 1.

Director and Professor, Department of Ophthalmology, Regional Institute of Ophthalmology, M.L.N. Medical College , Allahabad, U.P., India .

Tufted Angiomas also known as angioblastomas /Angioblastoma of Nagakawa are rare vascular neoplasms localised to the skin and subcutaneous tissues with the upper trunk and neck being most common sites. They are mainly seen in children but a few cases in juveniles and adults have been reported. We hereby report this case, a 40-year-old male who presented with a right lower lid, painless, slowly progressive, firm swelling diagnosed as Tufted Angioma on histopathology and immunohistochemistry. Read More

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http://dx.doi.org/10.7860/JCDR/2016/19270.8015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963661PMC
June 2016
3 Reads

Treatment of kaposiform hemangioendothelioma and tufted angioma.

Int J Cancer 2016 10 28;139(7):1658-66. Epub 2016 Jun 28.

College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

This meta-analysis was to evaluate the efficacy of current treatment modalities for kaposiform hemangioendothelioma and tufted angioma. A systematic review was performed using PubMed (Medline), Web of Science and Embase for clinical studies. The outcome was measured by pooled response rate with 95% confidence intervals (CIs), together with heterogeneity, subgroup analysis, sensitivity analysis and publication bias. Read More

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http://dx.doi.org/10.1002/ijc.30216DOI Listing
October 2016
57 Reads

Clinical Outcomes for Systemic Corticosteroids Versus Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma.

Medicine (Baltimore) 2016 May;95(20):e3431

From the Department of Oral Surgery (XL, CY, SZ); and Department of Oral-Maxillofacial Head and Neck Surgery (JZ, LZ), Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China; Key Laboratory of Orthopedic Implant (XQ), Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine; Jining Medical University (JL), Jining, Shandong Province; Pudong Institute of Preventive Medicine (WY), Fudan University, Shanghai, China.

A meta-analysis was performed to evaluate the efficacy and safety of systemic corticosteroids versus those of vincristine in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA).A literature search of PubMed, Embase, and Web of Science was performed for clinical studies on systemic corticosteroid versus vincristine therapies in treating KHE/TA. Pooled relative risks (RRs) and response rate with 95% confidence intervals (CIs) were used to measure outcomes. Read More

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http://dx.doi.org/10.1097/MD.0000000000003431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902390PMC
May 2016
42 Reads
1 Citation
5.723 Impact Factor

[Clinicopathologic study of pediatric vascular anomalies: a report of 117 cases].

Zhonghua Bing Li Xue Za Zhi 2016 Apr;45(4):252-7

Department of Pathology, Guangzhou Women and Children's Medical Center, Guangzhou 510623, China.

Objective: To study the clinicopathologic features of pediatric vascular anomalies and application of ISSVA classification.

Methods: The clinical features, histopathologic findings and immunohistochemical results were analyzed in 117 cases of pediatric vascular anomalies encountered during the period from May 2014 to May 2015.

Results: A total of 117 cases of vascular anomalies were studied. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2016.04.008DOI Listing
April 2016
15 Reads

Port-Wine Stain-Like Presentation of a Tufted Angioma on the Face.

Pediatr Dermatol 2016 Mar-Apr;33(2):e166-7

Department of Pediatrics, Children's Hospital at London Health Science Centre, Western University, London, ON, Canada.

Tufted angioma is an uncommon benign vascular tumor that typically is noted during infancy or childhood, with variable clinical presentation. We report the case of an infant with a tufted angioma initially presenting as a port-wine stain-like patch of the left cheek. Read More

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http://dx.doi.org/10.1111/pde.12805DOI Listing
January 2017
4 Reads

A Critical Analysis of Eleven Periocular Lobular Capillary Hemangiomas in Adults.

Am J Ophthalmol 2016 May 10;165:164-73. Epub 2016 Mar 10.

David G. Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye & Ear Infirmary; and the Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts. Electronic address:

Purpose: To provide a critical analysis of a series of periocular lobular capillary hemangiomas in adults, outlining characteristic clinical and histopathologic patterns in comparison with those of other vascular tumors of adults and children.

Design: Retrospective observational case series.

Methods: Review of clinical data, hematoxylin-eosin-stained sections, and immunohistochemical studies of smooth muscle actin (SMA), D2-40, CD34, and glucose transporter 1 (GLUT-1). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394163010
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http://dx.doi.org/10.1016/j.ajo.2016.03.010DOI Listing
May 2016
8 Reads

Tufted angioma.

Indian Dermatol Online J 2016 Jan-Feb;7(1):62-3

Department of Dermatology, Seth GS Medical College, King Edward Memorial Hospital, Mumbai, Maharashtra, India.

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http://dx.doi.org/10.4103/2229-5178.174313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763590PMC
March 2016
5 Reads

Tufted angioma of the maxilla: a rare case with unique clinical presentation.

Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Sep 19;122(3):e93-8. Epub 2015 Dec 19.

Department of Oral Medicine and Pathology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.

Tufted angioma is an uncommon benign vascular tumor usually presenting in early childhood and affecting mainly the skin. It has been associated with Kasabach-Merritt syndrome, a severe coagulopathy of poor prognosis. There have been very few published cases of oral tufted angiomas, and maxillary bone involvement has not been hitherto reported. Read More

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http://dx.doi.org/10.1016/j.oooo.2015.11.017DOI Listing
September 2016
6 Reads

[Clinicopathologic features and differential diagnoses of non-involuting congenital hemangioma in children].

Zhonghua Bing Li Xue Za Zhi 2015 Jul;44(7):495-8

Department of Pathology, Jiangxi Children's Hospital, Nanchang 330006, China; E-mail:

Objective: To investigate the clinicopathologic features and differential diagnoses of non-involuting congenital hemangioma (NICH) in children.

Methods: The clinical, morphologic and immunophenotypic characteristics of 22 cases of NICH were retrospectively analyzed.

Results: The mean patients' age at diagnosis was 4. Read More

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July 2015
17 Reads

Somatic p.T771R KDR (VEGFR2) Mutation Arising in a Sporadic Angioma During Ramucirumab Therapy.

JAMA Dermatol 2015 Nov;151(11):1240-3

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut2Department of Pathology, Yale University School of Medicine, New Haven, Connecticut3Department of Genetics, Yale University School of Medicine, New Haven, Connecticut.

Importance: Inhibition of angiogenesis is an effective anticancer strategy because neoplasms require a rich blood supply. Ramucirumab, approved by the US Food and Drug Administration in 2014 to treat gastric adenocarcinomas and non-small cell lung carcinomas, targets vascular endothelial growth factor 2 (VEGFR2). We identified a patient prescribed a regimen of irinotecan hydrochloride, cetuximab, and ramucirumab for metastatic rectal cancer (diagnosed in November 2013 and treated through early January 2015) who developed a new-onset, expanding vascular lesion on his right leg. Read More

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http://dx.doi.org/10.1001/jamadermatol.2015.1925DOI Listing
November 2015
4 Reads

A case of acquired tufted angioma in adulthood.

An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):16-8

Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda, Milan, IT.

Tufted angioma is a rare vascular tumor whose name derives from its histopathological appearance, characterized by tufts of capillaries within the dermis. Its etiology and pathogenesis are uncertain. Tufted angioma typically occurs during infancy or early childhood and displays various clinical patterns. Read More

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http://www.scielo.br/pdf/abd/v90n3s1/0365-0596-abd-90-03-s1-
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
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http://dx.doi.org/10.1590/abd1806-4841.20153733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540497PMC
January 2016
2 Reads

Multifocal Annular Tufted Angioma: An Uncommon Clinical Entity.

Indian J Dermatol 2015 Jul-Aug;60(4):422

Department of Dermatology, Venereology, and Leprosy, Medical College, Kolkata, West Bengal, India.

Tufted angioma (TA) is a localized benign hamartomatous vascular proliferation usually presenting in the childhood as an erythematous plaque. We report here a rare case of multifocal TA in an 8-year-old boy who presented which two large annular lesions as well as multiple papules and nodules on the back for the duration of 4 years. Histology showed typical well circumscribed poorly canalized vascular lobules with 'cannon ball' configuration. Read More

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http://dx.doi.org/10.4103/0019-5154.160528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4533571PMC
August 2015
5 Reads
1 Citation

A tufted angioma.

Indian Dermatol Online J 2015 Jul-Aug;6(4):266-8

Department of Dermatology, Comprehensive Dermatology Centre, Hyderabad, Andhra Pradesh, India.

Tufted angioma (TA) is a rare, benign, cutaneous angiomatous proliferation. It is more common in children, usually presenting as red-purple painful plaques on the trunk. We describe here a TA observed at nine months of age, appearing initially over the retroauricular area, gradually extending to involve skin of neck and trunk by two years of age. Read More

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http://www.idoj.in/text.asp?2015/6/4/266/160259
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http://dx.doi.org/10.4103/2229-5178.160259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513407PMC
July 2015
3 Reads