Clinical Characteristics of Connective Tissue Nevi in Tuberous Sclerosis Complex With Special Emphasis on Shagreen Patches.
- Michelle A Bongiorno,
- Neera Nathan,
- Oyetewa Oyerinde,
- Ji-An Wang,
- Chyi-Chia Richard Lee,
- G Thomas Brown,
- Joel Moss,
- Thomas N Darling
JAMA Dermatol 2017 Apr 26. Epub 2017 Apr 26.
Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, Maryland.
Importance: Patients with tuberous sclerosis complex (TSC) frequently develop collagenous connective tissue nevi. The prototypical lesion is a large shagreen patch located on the lower back, but some patients only manifest small collagenomas or have lesions elsewhere on the body. The ability to recognize these variable presentations can be important for the diagnosis of TSC. Read More