1,042 results match your criteria Tuberculosis Genitourinary Tract

Imaging Manifestations of Genitourinary Tuberculosis.

Radiographics 2021 May 28:200154. Epub 2021 May 28.

From the Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, Campus Box 8131, St Louis, MO 63110 (M.N., M.Z., A.S.S., C.S.); Department of Radiology, Division of Body Imaging, University of Missouri Health System, Columbia, Mo (M.A.S.); Department of Radiology, Division of Body Imaging, Sindh Institute of Urology and Transplantation, Civil Hospital, Karachi, Pakistan (A.H.); Department of Imaging, Division of Body Imaging, Clinica Davila, Recoleta, Chile (C.V.); and Department of Radiology, Division of Abdominal Imaging, Mayo Clinic Arizona, Scottsdale, Ariz (C.O.M.).

The genitourinary region is one of the most common sites of extrapulmonary tuberculosis (TB) involvement. The imaging features of genitourinary TB are protean and can mimic other entities, including malignancy, and pose a diagnostic dilemma. Hematogenous seeding and lymphatic spread of mycobacteria from pulmonary, tonsillar, and nodal TB are implicated in the pathogenesis of genitourinary TB. Read More

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The Differential Diagnosis of Sterile Pyuria in Pediatric Patients: A Review.

Donald W Bendig

Glob Pediatr Health 2021 6;8:2333794X21993712. Epub 2021 May 6.

CHOC Children's Hospital, Orange, CA, USA.

Sterile pyuria is a common finding in pediatric patients. Literature describing the diagnoses as well as clinical characteristics of children with sterile pyuria is lacking. This review was performed to establish an evidence-based approach to the differential diagnosis by way of an extensive literature search. Read More

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Engineering Vaccines for Tissue-Resident Memory T Cells.

Adv Ther (Weinh) 2021 Apr 20;4(4). Epub 2021 Jan 20.

Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee 37235, United States.

In recent years, tissue-resident memory T cells (T) have attracted significant attention in the field of vaccine development. Distinct from central and effector memory T cells, T cells take up residence in home tissues such as the lung or urogenital tract and are ideally positioned to respond quickly to pathogen encounter. T have been found to play a role in the immune response against many globally important infectious diseases for which new or improved vaccines are needed, including influenza and tuberculosis. Read More

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Abdominal Ascites of Unknown Origin: Diagnostic Accuracy of Adenosine Deaminase for Tuberculous Peritonitis.

Case Rep Gastroenterol 2021 Jan-Apr;15(1):418-423. Epub 2021 Apr 6.

Gastroenterology, BronxCare Health System, Bronx, New York, USA.

The occurrence of tuberculosis (TB) is exceedingly rare in the United States (US), and incidence has steadily declined since 1993, but the pace of decline has slowed in recent years. The US TB rate during 2019 declined to 2.7 cases per 100,000 persons, the lowest level on record. Read More

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Expanding the spectrum of reactive arthritis (ReA): classic ReA and infection-related arthritis including poststreptococcal ReA, Poncet's disease, and iBCG-induced ReA.

Rheumatol Int 2021 May 1. Epub 2021 May 1.

Department of Internal Medicine and Rheumatology, Juntendo University Koshigaya Hospital, Saitama, Japan.

Reactive arthritis (ReA) is a form of sterile arthritis that occurs secondary to an extra-articular infection in genetically predisposed individuals. The extra-articular infection is typically an infection of the gastrointestinal tract or genitourinary tract. Infection-related arthritis is a sterile arthritis associated with streptococcal tonsillitis, extra-articular tuberculosis, or intravesical instillation of bacillus Calmette-Guérin (iBCG) therapy for bladder cancer. Read More

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Diagnostic Value of PCR compared to Urine Culture for Urinary Tuberculosis in Adult Women: An Evidence-Based Case Report.

Acta Med Indones 2021 Jan;53(1):108-118

Department of Urology, Faculty of Medicine Universitas Indonesia - Cipto Mangunkusumo Hospital, Jakarta, Indonesia.

Background: genitourinary tuberculosis (GUTB) refers to a Mycobacterium tuberculosis infection of the urinary tract with clinical manifestation masquerading as various urological diagnostic entities. With an incidence rate of 192-232 per 100,000 individuals, current diagnoses have fallen short in comparison to the total incidence. Combined with an atypical and non-specific manifestation, a high false negative rate of acid-fast bacilli (AFB) staining, and long AFB culture duration has made diagnosis difficult. Read More

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January 2021

Biopsy-confirmed Genitourinary Tuberculosis in a Secondary Health Care Hospital: An Evidence-based Clinical Review.

Res Rep Urol 2021 17;13:133-137. Epub 2021 Mar 17.

Department of Urology, St. Carolus Hospital, Jakarta, Indonesia.

Introduction: Tuberculosis (TB) is a worldwide disease and remains a major public health problem in developing countries, with 95% of cases occurring in developing countries, including Indonesia. It is caused by , an acid-fast aerobic bacillus. When infects other than lung, it is called extrapulmonary tuberculosis (EPTB). Read More

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Genitourinary non-tuberculous mycobacterial (GU-NTM) infections: A single institution experience in South India.

Indian J Tuberc 2021 Jan 26;68(1):65-72. Epub 2020 Aug 26.

Former Senior Resident, Department of Urology, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham (Amrita University), Ponekkara, Cochin, Kerala, 682041, India.

Introduction: Non-tuberculous mycobacterial (NTM) infections are rarely reported, and more so with genitourinary infections. This retrospective study was designed to understand the proportion and behaviour of genitourinary non-tuberculous mycobacterial (GU-NTM) infections compared with genitourinary mycobacterial tuberculosis (GU-MTB) treated at a tertiary care hospital in South India.

Materials And Methods: The hospital records of every bacteriologically proved GU-MTB and GU-NTM infections treated at this centre from 2010 to 2016 were retrospectively reviewed. Read More

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January 2021

Unusual presentations of urogenital tuberculosis.

Int J Surg Case Rep 2020 25;77:769-772. Epub 2020 Nov 25.

Urology Department, Surgical Unit "Aghlabides" of Ibn Jazzar Hospital, Rue Hassan Ibn Nouaman, 3100, Kairouan, Tunisia. Electronic address:

Urogenital tuberculosis is a rare and severe disease since it causes serious consequences. Often, diagnosis may be delayed because of its multiple presentation forms and clinical features. Usually, the recognition is easy to hold, but in certain cases the presentation form can be misleading which can exclude the diagnosis. Read More

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November 2020

Diagnostic performance of EBUS-TBNA and its interrelation with PET-CT in patients with extra-thoracic malignancies.

Tuberk Toraks 2020 Sep;68(3):285-292

Department of Chest Diseases, Faculty of Medicine, Uludag University, Bursa, Turkey.

Introduction: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a well-established diagnostic tool for lung cancer, sarcoidosis, and suspected metastatic extra-thoracic malignancy (ETM). Patients with primary ETM often have hypermetabolic mediastinal/hilar lymph node enlargement in the PET-scan done for initial staging or post treatment followup. We aimed to determine the diagnostic performance of EBUS-TBNA and the relationship between PET-SUV values and diagnosis of malignancy metastasis in patients with ETM. Read More

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September 2020

Multimodality Imaging of Genitourinary Tuberculosis.

Curr Probl Diagn Radiol 2020 Nov 15. Epub 2020 Nov 15.

University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

Tuberculosis (TB) prevalence has increased over the past few decades, especially in the developing world. The genitourinary tract is the most common extra-pulmonary location of TB. Symptoms of genitourinary TB are often vague. Read More

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November 2020

[The features of the recurrence of urogenital tuberculosis].

Urologiia 2020 11(5):15-19

TB Research Institute of Ministry of Health of Russia, Novosibirsk, Russia.

Introduction: Tuberculosis is an infectious disease, which can result in self-cure, chronic process or relapse course.

Aim: To analyze the incidence of recurrence of urogenital tuberculosis and to identify the features of patients with recurrent disease.

Materials And Methods: Specially developed questionnaires on the structure of the incidence of extrapulmonary tuberculosis in the Siberian Federal District and the Far Eastern Federal District were analyzed. Read More

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November 2020

Length of hospital stay for TB varies with comorbidity and hospital location.

Int J Tuberc Lung Dis 2020 09;24(9):948-955

Lung Centre, Department of Pneumology and Sleep Medicine, Cantonal Hospital St Gallen, St Gallen, Tuberculosis Competence Centre, Swiss Lung Association, Berne, Switzerland.

Although most guidelines overwhelmingly recommend outpatient TB treatment, hospitalisations are common. We investigated the proportion of TB patients hospitalised and determined factors associated with length of stay (LOS) in Switzerland. Cases with TB as the primary diagnosis were retrieved from a nation-wide hospitalisation database and compared to TB notifications. Read More

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September 2020

Update on urogenital tuberculosis in Southern Tunisia: a review of a 26-year period.

Germs 2020 Sep 1;10(4):150-156. Epub 2020 Sep 1.

MD, Infectious Diseases Department and Extra-pulmonary Research Unity, Hedi Chaker University Hospital, University of Sfax, 3029, Tunisia.

Introduction: Tuberculosis affects commonly the lungs, but any other organs can be affected as well. Urogenital tuberculosis is usually misdiagnosed. In this perspective, we aimed to give an update on the epidemiological, clinical and evolutionary features of urogenital tuberculosis in Southern Tunisia. Read More

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September 2020

Male genital tract tuberculosis: A comprehensive review of imaging findings and differential diagnosis.

Abdom Radiol (NY) 2021 04 12;46(4):1677-1686. Epub 2020 Oct 12.

Department of Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Urogenital tuberculosis is the most common form of extrapulmonary tuberculosis. Genital organ involvement occurs as a continuum of urinary tract tuberculosis and often presents a diagnostic challenge due to the non-specific nature of the symptoms. Delay in diagnosis may lead to complications such as infertility and perineoscrotal sinuses. Read More

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Testicular tuberculosis: An uncommon complication after treatment of urothelial carcinoma.

Radiol Case Rep 2020 Nov 11;15(11):2285-2293. Epub 2020 Sep 11.

Morristown Medical Center, 100 Madison Avenue, Morristown, NJ 07960, USA.

Tuberculous epididymo-orchitis is an uncommon complication after intravesical bacilli Calmette-Guerin therapy for nonmuscle invasive bladder cancer. Spread of granulomatous disease through the genitourinary tract specifically to the testes occurs in 0.4% of treated patients. Read More

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November 2020

The best rules for antimicrobial stewardship in urogenital tract infections.

Curr Opin Urol 2020 11;30(6):838-844

Novosibirsk Research TB Institute, Novosibirsk, Russian Federation, Novosibirsk State Medical University Novosibirsk, Russian Federation.

Purpose Of Review: Urinary tract infections (UTIs) belong to the most common community-acquired and nosocomial infections, but therapy of UTIs is limited by resistance of pathogens and nonoptimal using of antibacterials. Narrative review of recent (2020-2018) literature dedicated to antimicrobial stewardship (AMS) in urological infections has been done.

Recent Findings: Analysis of recent 64 articles has shown following principles of AMS for UTIs: selecting the correct drug, correct dose, and shortest clinically effective duration of therapy whenever possible, is a base for optimal antimicrobial stewardship; symptomatic UTIs should be treated with antimicrobials to alleviate symptoms, and in the case of more serious infection, to prevent complications; in both symptomatic and asymptomatic infection, quantitative culture is the gold standard for diagnosis; we have to avoid prescriptions of antibiotics when possible; we have to follow European and National Guidelines; we must avoid prescription of fluoroquinolones as empiric therapy for UTIs by many reasons, one of these is urogenital tuberculosis; the choice of antibiotic for UTI should be based on local level of resistance of uropathogens. Read More

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November 2020

Tuberculosis: A granulomatous disease mediated by epigenetic factors.

Tuberculosis (Edinb) 2020 07 30;123:101943. Epub 2020 May 30.

Tropical Medicine Center, Faculty of Medicine, University of Brasília, Brazil; Morphology Area, Faculty of Medicine, University of Brasília, Brazil. Electronic address:

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis, which is transmitted via aerosol. TB is a secular fatal disease which still represents a health problem worldwide. TB has long incubation period and usually at first, affects the lungs. Read More

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A rare association of infection of kidney and urinary tract with immunoglobulin A nephropathy.

Indian J Med Microbiol 2019 Oct-Dec;37(4):587-589

Department of Nephrology, Madras Medical Mission, Chennai, Tamil Nadu, India.

Mycobacterium tuberculosis(MTB)-related secondary immunoglobulin A (IgA) nephropathy is reported in a 72-year-old male patient. The patient was diagnosed to have MTB infection of the kidney and genitourinary tract which was diagnosed by the demonstration of the organism by GeneXpert Ultra and culture. Concurrent kidney biopsy showed IgA nephropathy. Read More

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Urinary tuberculosis: still a challenge.

World J Urol 2020 Nov 21;38(11):2693-2698. Epub 2020 Mar 21.

Department of Urology, Istanbul Medipol University, Istanbul, Turkey.

Background: Urinary tuberculosis (TB) is a challenging disease to cope with, as there has been no noticeable difference in basic diagnostic and therapeutic options in clinical practice over time.

Purpose: The aim of the current review was the critical assessment and evaluation of TB, which remains a major global health problem.

Methods: The available literature regarding TB in the PubMed database was extensively searched. Read More

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November 2020

Female genital tuberculosis in light of newer laboratory tests: A narrative review.

Indian J Tuberc 2020 Jan 18;67(1):112-120. Epub 2020 Jan 18.

Department of Clinical Research, ICMR-National Institute for Research in Reproductive Health (NIRRH), JM Street, Parel, 400012, Mumbai, India. Electronic address:

Female genital tract tuberculosis (FGTB) is a chronic disease with varied presentation. The diagnosis of FGTB for early institution of treatment remains a clinical challenge. Its laboratory diagnosis is difficult because of paucibacillary nature of the condition and limitation of available diagnostic tests. Read More

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January 2020

Urological infections in the developing world: an increasing problem in developed countries.

World J Urol 2020 Nov 27;38(11):2681-2691. Epub 2020 Feb 27.

Department of Urology, All India Institute of Medical Sciences, New Delhi, India.

Purpose: Infectious diseases that often follow geographical distribution patterns are increasingly crossing such boundaries, aided by human travel and commerce. These pose a new challenge to physicians who are required to diagnose previously unseen conditions and address drug-resistant organisms. We review some such common infections. Read More

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November 2020

Vulvar tuberculosis.

BMJ Case Rep 2020 Feb 11;13(2). Epub 2020 Feb 11.

Pathology, King George Medical University, Lucknow, Uttar Pradesh, India.

Genital tuberculosis (TB) in women is a chronic disease with low-grade symptoms. Genital tract tuberculosis is usually secondary to extragenital TB. The fallopian tubes are most commonly affected, and along with endometrial involvement, it causes infertility in such patients. Read More

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February 2020

Application of whole-genome sequencing in a case study of renal tuberculosis in a child.

BMC Infect Dis 2020 Feb 5;20(1):105. Epub 2020 Feb 5.

Latvian Biomedical Research and Study Centre, Ratsupites Str 1, k-1, Riga, LV-1067, Latvia.

Background: Urogenital tuberculosis (TB) is rare in children and usually develops due to reactivation of the foci in the genitourinary tract after the latency period following initial infection. Urogenital TB in children has no pathognomonic clinical features that can result in overlooking or misdiagnosing this clinical entity. Here, we report important findings regarding the pathogenesis and transmission of TB by using genotyping and whole-genome sequencing (WGS) in a study of renal TB case in a child. Read More

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February 2020

Atypical manifestations of granulomatosis with polyangiitis: the diagnostic challenge for pulmonologists.

Adv Respir Med 2019 ;87(6):244-253

Department of Allergology, Medical University of Gdańsk, Gdańsk, Poland.

This is a review considering atypical manifestations of granulomatosis with polyangiitis (GPA). Virtually any organ can be affected, and in some patients, GPA can manifest unusually. Since thoracic involvement of GPA often predominates, the first who might be expected to establish a diagnosis are pulmonary specialists. Read More

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Is sterile pyuria another minor diagnostic criterion in urinary tuberculosis?

Indian J Tuberc 2019 Oct 15;66(4):468-473. Epub 2019 Aug 15.

Department of Urology, Institute of Nephrourology, Victoria Hospital Campus, Bangalore 560002, India. Electronic address:

Introduction: Composite reference standard (CRS) is used for diagnosis of urinary tract tuberculosis (UTB). We examined if addition of a new 'component test' as minor criterion in the form of SP could improve the yield.

Methods: We identified patients admitted with a diagnosis of UTB from January 2009 to February 2016 from our patient database. Read More

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October 2019

Evaluation of Multiplex PCR for Rapid Diagnosis of Female Genital Tuberculosis.

J Assoc Physicians India 2019 Dec;67(12):21-24

Department of Medical Microbiology.

Background: Female genital tract tuberculosis (FGTB) is a very common disease in developing countries. Rapid and specific diagnosis is of paramount importance.

Purpose: To evaluate Multiplex PCR using MPB 64 and IS6110 primers directed against M. Read More

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December 2019

Tuberculous prostatitis: a condition not confined to the immunocompromised.

S Afr J Surg 2019 Dec;57(4):43

Department of Urology, Helen Joseph Hospital, University of Witwatersrand, Johannesburg, South Africa.

Summary: Tuberculous (TB) prostatitis is rare; usually occurring in immunocompromised men. It can mimic benign prostatic hyperplasia (BPH), chronic prostatitis or prostate cancer. This report in an immunocompetent 72-year-old man adds to the clinical spectrum of the five prior reported cases. Read More

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December 2019

Peritoneal and upper genital tract tuberculosis.

Med Glas (Zenica) 2020 Feb;17(1):86-91

Gynecological Tumour Centre and European Competence Centre for Ovarian Cancer, Charité Universitätsmedizin Berlin, Germany.

Aim To present diagnostic and therapeutic possibilities for genital and peritoneal tuberculosis, mimicking to other pathological conditions, mainly, ovarian cancer. Methods Transabdominal and transvaginal ultrasound, computerized tomography, Ca125 and HE 4, ROMA- index (Risk of Ovarian Maligancy Algorithm index) and diagnostic laparoscopy were performed in order to diagnose genital tuberculosis in a female patient. Results: A 23-year-old woman from Morocco presented with intermitting abdominal pain, unintentional weight loss and primary infertility. Read More

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February 2020