1,017 results match your criteria Tuberculosis Genitourinary Tract


A rare association of infection of kidney and urinary tract with immunoglobulin A nephropathy.

Indian J Med Microbiol 2019 Oct-Dec;37(4):587-589

Department of Nephrology, Madras Medical Mission, Chennai, Tamil Nadu, India.

Mycobacterium tuberculosis(MTB)-related secondary immunoglobulin A (IgA) nephropathy is reported in a 72-year-old male patient. The patient was diagnosed to have MTB infection of the kidney and genitourinary tract which was diagnosed by the demonstration of the organism by GeneXpert Ultra and culture. Concurrent kidney biopsy showed IgA nephropathy. Read More

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http://dx.doi.org/10.4103/ijmm.IJMM_19_482DOI Listing

Urological infections in the developing world: an increasing problem in developed countries.

World J Urol 2020 Feb 27. Epub 2020 Feb 27.

Department of Urology, All India Institute of Medical Sciences, New Delhi, India.

Purpose: Infectious diseases that often follow geographical distribution patterns are increasingly crossing such boundaries, aided by human travel and commerce. These pose a new challenge to physicians who are required to diagnose previously unseen conditions and address drug-resistant organisms. We review some such common infections. Read More

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http://dx.doi.org/10.1007/s00345-020-03120-3DOI Listing
February 2020

Application of whole-genome sequencing in a case study of renal tuberculosis in a child.

BMC Infect Dis 2020 Feb 5;20(1):105. Epub 2020 Feb 5.

Latvian Biomedical Research and Study Centre, Ratsupites Str 1, k-1, Riga, LV-1067, Latvia.

Background: Urogenital tuberculosis (TB) is rare in children and usually develops due to reactivation of the foci in the genitourinary tract after the latency period following initial infection. Urogenital TB in children has no pathognomonic clinical features that can result in overlooking or misdiagnosing this clinical entity. Here, we report important findings regarding the pathogenesis and transmission of TB by using genotyping and whole-genome sequencing (WGS) in a study of renal TB case in a child. Read More

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http://dx.doi.org/10.1186/s12879-020-4832-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003358PMC
February 2020

Atypical manifestations of granulomatosis with polyangiitis: the diagnostic challenge for pulmonologists.

Adv Respir Med 2019 ;87(6):244-253

Department of Allergology, Medical University of Gdańsk, Gdańsk, Poland.

This is a review considering atypical manifestations of granulomatosis with polyangiitis (GPA). Virtually any organ can be affected, and in some patients, GPA can manifest unusually. Since thoracic involvement of GPA often predominates, the first who might be expected to establish a diagnosis are pulmonary specialists. Read More

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http://dx.doi.org/10.5603/ARM.2019.0062DOI Listing
January 2019

Is sterile pyuria another minor diagnostic criterion in urinary tuberculosis?

Indian J Tuberc 2019 Oct 15;66(4):468-473. Epub 2019 Aug 15.

Department of Urology, Institute of Nephrourology, Victoria Hospital Campus, Bangalore 560002, India. Electronic address:

Introduction: Composite reference standard (CRS) is used for diagnosis of urinary tract tuberculosis (UTB). We examined if addition of a new 'component test' as minor criterion in the form of SP could improve the yield.

Methods: We identified patients admitted with a diagnosis of UTB from January 2009 to February 2016 from our patient database. Read More

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http://dx.doi.org/10.1016/j.ijtb.2019.08.004DOI Listing
October 2019

Evaluation of Multiplex PCR for Rapid Diagnosis of Female Genital Tuberculosis.

J Assoc Physicians India 2019 Dec;67(12):21-24

Department of Medical Microbiology.

Background: Female genital tract tuberculosis (FGTB) is a very common disease in developing countries. Rapid and specific diagnosis is of paramount importance.

Purpose: To evaluate Multiplex PCR using MPB 64 and IS6110 primers directed against M. Read More

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December 2019

Tuberculous prostatitis: a condition not confined to the immunocompromised.

S Afr J Surg 2019 Dec;57(4):43

Department of Urology, Helen Joseph Hospital, University of Witwatersrand, Johannesburg, South Africa.

Summary: Tuberculous (TB) prostatitis is rare; usually occurring in immunocompromised men. It can mimic benign prostatic hyperplasia (BPH), chronic prostatitis or prostate cancer. This report in an immunocompetent 72-year-old man adds to the clinical spectrum of the five prior reported cases. Read More

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December 2019

[Tuberculous vesicovaginal fistula complicated by bladder stones: about an exceptional case].

Pan Afr Med J 2019 19;33:126. Epub 2019 Jun 19.

Service d'Anatomopathologie, Centre Hospitalier Universitaire Hassan II de Fès, Fès, Maroc.

Vesicovaginal fistula (VVF) continues to be a major public health problem in developing countries. Given the particular association of VVF with stones, the question that arises is whether the fistula is primary or secondary to bladder stone and then whether to use single-stage or two-stage treatment. But what is special about this study is that these rare clinical features are due to tuberculosis. Read More

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http://dx.doi.org/10.11604/pamj.2019.33.126.16674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754842PMC
October 2019
5 Reads

[Urological infections and migration].

Urologe A 2019 Oct;58(10):1219-1230

Universität Basel, Basel, Schweiz.

In the context of refugee migrations infectious diseases are being more frequently diagnosed, which the responsible physicians as well as urologists have never seen before. This is due to the poorer health and hygiene conditions in the country of origin, during the flight and in the refugee camps. In Europe increasing incidences of tuberculosis, schistosomiasis and scabies have recently been observed. Read More

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http://dx.doi.org/10.1007/s00120-019-01040-8DOI Listing
October 2019
2 Reads

Urogenital tuberculosis - epidemiology, pathogenesis and clinical features.

Nat Rev Urol 2019 10 23;16(10):573-598. Epub 2019 Sep 23.

Department of Clinical Microbiology, University College London Hospitals NHS Foundation Trust, London, UK.

Tuberculosis (TB) is the most common cause of death from infectious disease worldwide. A substantial proportion of patients presenting with extrapulmonary TB have urogenital TB (UG-TB), which can easily be overlooked owing to non-specific symptoms, chronic and cryptic protean clinical manifestations, and lack of clinician awareness of the possibility of TB. Delay in diagnosis results in disease progression, irreversible tissue and organ damage and chronic renal failure. Read More

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http://dx.doi.org/10.1038/s41585-019-0228-9DOI Listing
October 2019
3 Reads

Epididymis tuberculosis: Case report and brief review of the literature.

Urol Case Rep 2019 Sep 16;26:100969. Epub 2019 Jul 16.

Department of Urology, Federal University of Espírito Santo, Vitória, ES, Brazil.

Tuberculosis (TB) is a secular disease caused by a bacillus, highly prevalent in Brazil. The genito-urinary tract involvement is rare, with the epididymis the most affected location. Treatment usually involves the combination of 3-4 drugs for TB for 6 months and surgery can be useful in complications. Read More

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http://dx.doi.org/10.1016/j.eucr.2019.100969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656682PMC
September 2019
3 Reads

Multicentre evaluation of Xpert MTB/RIF assay in detecting urinary tract tuberculosis with urine samples.

Sci Rep 2019 07 30;9(1):11053. Epub 2019 Jul 30.

School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 1/F, Patrick Manson Building (North), 7 Sassoon Road, Pokfulam, Hong Kong, Special Administrative Region, P.R. China.

Genitourinary tuberculosis (GUTB) accounts for up to 40% of extrapulmonary tuberculosis cases. Rapid tests for GUTB are urgently needed because it is often associated with delayed health-care seeking, leading to serious consequences. This study evaluated the performance of the Xpert MTB/RIF assay in the rapid diagnosis of urinary tract tuberculosis (UTB) and rifampicin-resistant tuberculosis with urine specimens. Read More

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http://dx.doi.org/10.1038/s41598-019-47358-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667469PMC
July 2019
3 Reads

Mycobacterium abscessus urinary tract infection: case report.

J Bras Nefrol 2020 Mar 30;42(1):124-126. Epub 2019 May 30.

Hospital das Forças Armadas, Brasília, DF, Brasil.

Urinary tract infection is a serious public health issue that predominantly affects women. In men, it is more often associated with prostatic hyperplasia and bladder catheterization. Urogenital tuberculosis presents with nonspecific with nonspecific symptoms and the diagnosis can be made in the presence of sterile leukocyturia and recurrent infection with acid urine. Read More

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http://dx.doi.org/10.1590/2175-8239-JBN-2018-0260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213923PMC
March 2020
6 Reads

The epidemiology of bacille Calmette-Guérin infections after bladder instillation from 2002 through 2017: a nationwide retrospective cohort study.

BJU Int 2019 12 31;124(6):910-916. Epub 2019 May 31.

Department of Infectious Diseases, Odense University Hospital, Odense, Denmark.

Objective: To describe incidence and clinical characteristics of bacille Calmette-Guérin (BCG) infections after BCG bladder instillation amongst patients with non-muscle-invasive bladder cancer in Denmark.

Patients And Methods: We conducted a nationwide register-based cohort study in Denmark between 2002 through 2017. Patients with BCG infection were identified by cross-linking data from the Danish National Hospital Registry on patients treated with BCG instillations and patients diagnosed with tuberculosis according to the International Classification of Diseases 10, and data obtained from International Reference Laboratory of Mycobacteriology. Read More

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http://dx.doi.org/10.1111/bju.14793DOI Listing
December 2019
4 Reads

Challenges in urogenital tuberculosis.

World J Urol 2020 Jan 17;38(1):89-94. Epub 2019 Apr 17.

Novosibirsk Research TB Institute, Urogenital Clinic, Novosibirsk, Russian Federation.

Purpose: For better understanding of urogenital tuberculosis (UGTB), its clinical spectrum and characteristic features need to be evaluated.

Materials And Methods: One hundred and forty-two cases of UGTB patients were analyzed retrospectively. We considered age, gender, symptoms, and diagnostic procedures. Read More

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http://dx.doi.org/10.1007/s00345-019-02767-xDOI Listing
January 2020
10 Reads

Demographic risk factors for extra-pulmonary tuberculosis among adolescents and adults in Saudi Arabia.

PLoS One 2019 27;14(3):e0213846. Epub 2019 Mar 27.

Department of Infection and Immunity, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Despite low infectious potential of extrapulmonary tuberculosis (EPTB), it poses significant clinical challenges in terms of diagnosis and treatment monitoring. Understanding the main demographical risk factors for disease characteristics of EPTB plays a crucial role in speeding up diagnosis process and improving overall clinical experience. The aim of this study was to investigate the main demographical and clinical risk factors for EPTB among adults and adolescents for the first time in Saudi Arabia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436801PMC
December 2019
1 Read
3.234 Impact Factor

Common Infections and Target Organs Associated with Chronic Granulomatous Disease in Iran.

Int Arch Allergy Immunol 2019;179(1):62-73. Epub 2019 Mar 22.

Cell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom,

Recurrent severe bacterial and fungal infections are characteristic features of the rare genetic immunodeficiency disorder chronic granulomatous disease (CGD). The disease usually manifests within the first years of life with an incidence of 1 in approximately 200,000 live births. The incidence is higher in Iran and Morocco where it reaches 1. Read More

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http://dx.doi.org/10.1159/000496181DOI Listing
May 2019
11 Reads
2.673 Impact Factor

Atypical testicular pain.

BMJ Case Rep 2019 Feb 19;12(2). Epub 2019 Feb 19.

Urological Surgery, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Frimley, UK.

Testicular tuberculosis (TB) is rare, and, because of this, the lack of pathognomonic clinical features and its tendency to mimic other commoner conditions, the diagnosis is frequently delayed or may be missed. In this case, the initial clinical presentation was typical for bacterial epididymo-orchitis in a 38-year-old man. When the patient failed to improve with standard treatment including broadening of antibiotics, the diagnosis was re-considered because some unusual signs suggested testicular malignancy or lymphoma. Read More

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http://dx.doi.org/10.1136/bcr-2018-226697DOI Listing
February 2019
13 Reads

Esophageal Stricture Caused by in a Patient with No Apparent Predisposing Factors.

Case Rep Gastrointest Med 2019 2;2019:7182976. Epub 2019 Jan 2.

Division of Gastroenterology and Hepatobiliary Diseases, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, 11215, USA.

species are Gram positive anaerobic or microaerophilic bacteria that are part of the human flora in the oropharyngeal, gastrointestinal, and genitourinary tract. In the presence of a mucosal injury, they can become pathogenic and infect the underlying tissue without respect for tissue planes, leading to abscesses, fistulas, and sinus tracts. Through contiguous and hematogenous spread, virtually any organ can become infected. Read More

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https://www.hindawi.com/journals/crigm/2019/7182976/
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http://dx.doi.org/10.1155/2019/7182976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334373PMC
January 2019
36 Reads

Medical treatment for urogenital tuberculosis (UGTB).

Authors:
Christian Wejse

GMS Infect Dis 2018 9;6:Doc04. Epub 2018 Aug 9.

Department of Infectious Diseases/Center for Global Health, Dept of Public Health, Aarhus University, Denmark.

Urogenital tuberculosis (UGTB) should in general be treated as pulmonary TB with a four-drug regimen of Isoniazid, Rifampicin, Ethambutol and Pyrazinamide for a total of 6 months, Ethambutol and Pyrazinamide only the first two months. Some patients may need longer treatment (cavitary disease, kidney abscess/malfunction, HIV co-infection). Treatment of multi-drug resistant tuberculosis (MDR-TB) requires use of long-term intravenous treatment with aminoglycosides and other drugs with considerable toxicity for 18-24 months. Read More

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http://dx.doi.org/10.3205/id000039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301712PMC
August 2018
13 Reads

Genitourinary Tract Infection Due to Mycobacterium avium intracellulare Complex Infection in Pretransplant Setting With Recurrence Following Transplant: A Case Report.

Transplant Proc 2018 Dec 8;50(10):3937-3939. Epub 2018 Sep 8.

Program in Adult Transplant Infectious Disease, Division of Infectious Disease and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

Genitourinary (GU) tract infection with Mycobacterium avium intracellulare complex (MAI) is very rare and, to our knowledge, has never been reported in the solid organ transplant literature. CASE DESCRIPTION: A 61-year-old Somali-born woman had a history of liver cirrhosis due to chronic hepatitis C infection. She was diagnosed as having and treated for latent tuberculosis infection and GU tract infection due to MAI. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00411345183116
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http://dx.doi.org/10.1016/j.transproceed.2018.09.007DOI Listing
December 2018
40 Reads

Primary cutaneous 'ulcerative' tuberculosis of the scrotum: a rare occurrence.

BMJ Case Rep 2018 Dec 19;11(1). Epub 2018 Dec 19.

General Surgery, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Tuberculosis (TB) is a global disease and if not adequately treated can lead to morbidity and mortality. Though genitourinary TB is common and only next to pulmonary TB, cutaneous 'ulcerative' tuberculosis of the scrotum is not reported so far in the literature. We present a 32-year-old man with a non-healing scrotal ulcer and underwent excision. Read More

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http://dx.doi.org/10.1136/bcr-2018-227177DOI Listing
December 2018
16 Reads

Curious case of fever of unknown origin.

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Professor, Department of Medicine, All India Institute of Medical Sciences, New Delhi.

A 58-year-old immunocompetent woman presented with fever and significant weight loss of 4-month duration. She had mild pallor; rest of the examination was unremarkable. Investigations revealed anaemia with raised inflammatory markers. Read More

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http://dx.doi.org/10.1136/bcr-2018-227258DOI Listing
December 2018
27 Reads

Tuberculous ureteritis.

QJM 2019 May;112(5):371-372

Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.

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http://dx.doi.org/10.1093/qjmed/hcy275DOI Listing

Genitourinary tuberculosis in Taiwan: A 15-year experience at a teaching hospital.

J Microbiol Immunol Infect 2019 Apr 9;52(2):312-319. Epub 2018 Nov 9.

Department of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital-Linkou Medical Center, Chang Gung University College of Medicine, Taoyuan, Taiwan. Electronic address:

Background: Genitourinary tuberculosis (GUTB) is rare but fatal if not diagnosed early. The purpose of this study was to investigate the outcomes of GUTB in Taiwan.

Methods: We retrospectively reviewed medical records of 57 patients who were diagnosed as GUTB from January 2002 to December 2016, over a 15-year period. Read More

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http://dx.doi.org/10.1016/j.jmii.2018.10.007DOI Listing
April 2019
10 Reads

[Urogenital tuberculosis and schistosomiasis (bilharzia) : Urological challenges in displaced persons].

Urologe A 2018 Oct;57(10):1191-1199

Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg - Standort Gießen, Gießen, Deutschland.

We are observing the largest worldwide wave of migration ever. Displaced persons usually do not have access to general health care and are faced with a lack of hygienic conditions and infection control while fleeing, which leads to an accumulation of "exotic" infectious diseases. The number of patients with tuberculosis (TB) had declined for many years in Germany; however, increasing numbers of cases have recently been observed. Read More

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http://dx.doi.org/10.1007/s00120-018-0760-xDOI Listing
October 2018
54 Reads

Recurrent bilateral Mycobacterium bovis necrotizing epididymitis: a case report.

BMC Res Notes 2018 May 18;11(1):308. Epub 2018 May 18.

Aix-Marseille Univ, IRD, MEPHI, IHU Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005, Marseille, France.

Background: Mycobacterium bovis causing tuberculosis in animals is responsible for zoonotic tuberculosis in patients. Veterinary control measures and milk pasteurization has led to a significant decrease in human cases of M. bovis infections in developed countries. Read More

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http://dx.doi.org/10.1186/s13104-018-3426-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960082PMC
May 2018
71 Reads

Surprising pathological and clinical manifestations of miliary tuberculosis.

BMJ Case Rep 2018 May 12;2018. Epub 2018 May 12.

Department of Medicine, University of Hawaii, Honolulu, Hawaii, USA.

We report a surprising pathological finding of miliary tuberculosis (TB) in a 49-year-old Chuukese, immunocompetent woman who was initially admitted to the hospital for a 1-month duration of chronic abdominal pain and intermittent fevers. Her clinical symptoms did not improve despite treatment with vancomycin and piperacillin-tazobactam. Based on the primary abdominal CT findings suggesting advanced ovarian cancer with omental metastatic disease, further workup with omental core biopsy was performed and demonstrated acute neutrophilic necrosis without malignant cells or granulomata. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2017-22336
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http://dx.doi.org/10.1136/bcr-2017-223360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965806PMC
May 2018
13 Reads

The Wrong Frame of Mind.

N Engl J Med 2018 05;378(18):1716-1721

From the William S. Middleton Memorial Veterans Hospital and the Department of Medicine (J.A.M., A.J.L., N.S.) and Department of Pediatrics (J.A.M.), University of Wisconsin-Madison School of Medicine, Madison; the Department of Internal Medicine, University of Michigan Medical School, and the Department of Veterans Affairs (VA) Health Services Research and Development Center of Excellence - both in Ann Arbor (S.S.); and the Medical Service, San Francisco VA Medical Center, and the Department of Medicine, University of California, San Francisco - both in San Francisco (G.D.).

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http://dx.doi.org/10.1056/NEJMcps1710814DOI Listing
May 2018
23 Reads

Urogenital tuberculosis, the cause of ineffective antibacterial therapy for urinary tract infections.

Ther Adv Urol 2018 Mar 22;10(3):95-101. Epub 2017 Dec 22.

Federal State Budgetary Institution 'The Novosibirsk Tuberculosis Research Institute (NTRI)' of the Ministry of Health of the Russian Federation, Russian Federation.

Background: Urogenital tuberculosis (UGTB) is one of the great imitators; it is commonly masked by urinary tract infections (UTIs). We aimed to estimate how many UGTB patients were among patients with a long history of UTIs.

Material And Methods: A total of 244 patients with recurrent UTIs and suspected UGTB were enrolled in an open, noncomparative prospective study. Read More

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http://dx.doi.org/10.1177/1756287217745772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896858PMC
March 2018
18 Reads

Tuberculosis of the Urogenital Tract in Adults in a Tertiary Referral Center.

Adv Exp Med Biol 2018 ;1040:29-37

Department of Family Medicine, Medical University of Warsaw, 1A Banacha Street, 02-097, Warsaw, Poland.

The genitourinary system is the main location of extrapulmonary tuberculosis. In Poland, it occupies the third place after tuberculosis of the pleura and lymph nodes. The aim of this study was to evaluate the prevalence and characteristics of tuberculosis in the urogenital tract in adult patients in a tertiary referral center in the years 2007-2015. Read More

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http://dx.doi.org/10.1007/5584_2017_103DOI Listing
October 2018
13 Reads

[Is there screening for urinary tuberculosis?]

Urologiia 2017 Dec(6):34-37

Novosibirsk Tuberculosis Research Institute of Minzdrav of Russia, 2Novosibirsk State Medical University of Minzdrav of Russia, Novosibirsk, Russia.

Introduction: Most of the patients with genitourinary tuberculosis are detected too late. One of the reasons for this is the lack of a simple, cheap, reliable screening. The purpose of this study was to investigate the possibility of using a recombinant tuberculosis allergen (diaskintest) as a screening test to detect patients with genitourinary tuberculosis. Read More

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December 2017
7 Reads

Tuberculosis epididymitis complicated by a cutaneous fistula.

BMJ Case Rep 2017 Nov 9;2017. Epub 2017 Nov 9.

Department of Surgery, Alta Bates Summit Medical Center, Berkeley, California, USA.

A 63-year-old man developed scrotal swelling that became bilateral over 2 months. His symptoms persisted after treatment for epididymitis, and he developed a scrotal fistula with drainage. grew from the urine and fistula. Read More

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http://dx.doi.org/10.1136/bcr-2017-221346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695325PMC
November 2017
6 Reads

Tuberculous pyelonephritis in children: three case reports.

Paediatr Int Child Health 2017 Nov 1;37(4):292-297. Epub 2017 Nov 1.

b Division of Pediatric Nephrology, Department of Pediatrics , Postgraduate Institute of Medical Education & Research and Associated Dr. Ram Manohar Lohia Hospital , New Delhi , India.

Tuberculous pyelonephritis is rare in children; three case reports are presented. Case 1 was an 11-year-old girl with a previous history of pulmonary tuberculosis who presented with flank pain and fever for 10 days. An ultrasound suggested focal pyelonephritis, and a contrast-enhanced computed tomography (CECT) scan demonstrated acute focal pyelonephritis and a perinephric collection. Read More

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http://dx.doi.org/10.1080/20469047.2017.1386847DOI Listing
November 2017
26 Reads

Obstructive uropathy as initial presentation of genitourinary tuberculosis and masquerading as a postsurgical complication.

BMJ Case Rep 2017 Oct 15;2017. Epub 2017 Oct 15.

Department of Internal Medicine, University Teaching Hospital of Kigali, Kigali, Rwanda.

A 46-year-old woman who had a recent total abdominal hysterectomy presented with a 1 month history of lower abdominal pain, 1 week of nausea and vomiting as well as decreased urinary output preceded by a year of significant unintentional weight loss. On renal imaging, she was found to have bilateral hydronephrosis and hydroureters in the setting of bilateral distal ureteric obstruction complicated with acute kidney injury and severe hyperkalaemia requiring haemodialysis. The initial concern was for ureteric injury, a known complication of abdominal hysterectomy procedures, however, a urological intervention, performed 9 months later to relieve the ureteric obstruction, revealed purulent material within the left ureter that was smear positive for acid fast bacilli. Read More

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http://dx.doi.org/10.1136/bcr-2017-221270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652372PMC
October 2017
29 Reads

Genital tuberculosis in females.

Indian J Med Res 2017 Apr;145(4):425-436

Department of Clinical Research, ICMR-National Institute for Research in Tuberculosis, Chennai, India.

The morbidity and mortality due to tuberculosis (TB) is high worldwide, and the burden of disease among women is significant, especially in developing countries. Mycobacterium tuberculosis bacilli reach the genital tract primarily by haematogenous spread and dissemination from foci outside the genitalia with lungs as the common primary focus. Genital TB in females is a chronic disease with low-grade symptoms. Read More

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http://dx.doi.org/10.4103/ijmr.IJMR_1550_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5663156PMC
April 2017
82 Reads

Urine trouble: genitourinary tuberculosis and subsequent DRESS syndrome.

BMJ Case Rep 2017 Aug 7;2017. Epub 2017 Aug 7.

Albert Einstein College of Medicine, Yeshiva University, Bronx, New York, USA.

A 40-year-old woman with HIV (CD4 270, viral load undetectable) from Zambia presented with fevers, urinary tract infection symptoms, sterile pyuria and haematuria. She was found to have genitourinary tuberculosis (TB) via mycobacterial culture of urine and ascites, and treated with rifabutin, isoniazid, pyrazinamide and ethambutol. She later had multiple episodes of asymptomatic transaminitis, triggering changes to both TB and HIV regimens. Read More

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http://dx.doi.org/10.1136/bcr-2017-220440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623288PMC
August 2017
10 Reads

The incidence of subclinical forms of urogenital tuberculosis in patients with pulmonary tuberculosis.

J Infect Public Health 2018 Mar - Apr;11(2):243-245. Epub 2017 Jul 27.

Department of Clinical Microbiology, Thomayer Hospital, Videnska 800, 140 59 Prague 4, Czech Republic; Department of Laboratory Medicine, 3rd Faculty of Medicine, Charles University, Prague, Czech Republic. Electronic address:

The aim of our study was to determine whether patients with pulmonary tuberculosis may have subclinical forms of urogenital tuberculosis. Between 2011 and 2012, a prospective study was conducted. Basic demographic parameters were recorded and the following investigations were performed: direct bacilloscopy of sputum, evaluation of affected lung fields and presence of cavities on chest X-ray, Mantoux tuberculin skin test II, and interferon gamma release assay. Read More

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http://dx.doi.org/10.1016/j.jiph.2017.07.005DOI Listing
November 2018
90 Reads

Etiologic and differential diagnostic significance of tumor location in the supraclavicular fossa.

Laryngoscope 2018 03 20;128(3):646-650. Epub 2017 Jul 20.

Department of Otorhinolaryngology, Head and Neck Surgery, Charite'-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

Objective: Patients presenting with a cervical mass are common for head and neck specialists and present a diagnostic challenge against the backdrop of a wide variety of etiologies. The objective of the present study was to evaluate the significance of a mass in the supraclavicular fossa for etiology, diagnostic procedure, and therapy.

Study Design: Individual retrospective cohort study. Read More

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http://doi.wiley.com/10.1002/lary.26775
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http://dx.doi.org/10.1002/lary.26775DOI Listing
March 2018
12 Reads

Does pyuria always suggest urinary tract infection with common microorganisms? Answers.

Pediatr Nephrol 2018 04 18;33(4):615-617. Epub 2017 Jul 18.

Department of Pulmonology, Ministry of Health, Bağcılar Education and Research Hospital, Istanbul, Turkey.

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http://dx.doi.org/10.1007/s00467-017-3734-0DOI Listing
April 2018
8 Reads

Does pyuria always suggest urinary tract infection with common microorganisms? Questions.

Pediatr Nephrol 2018 04 18;33(4):611-613. Epub 2017 Jul 18.

Department of Pulmonology, Ministry of Health, Bağcılar Education and Research Hospital, Istanbul, Turkey.

Genitourinary system tuberculosis (GUTB) is a chronic granulomatous infection in which tuberculous bacilli affect one or more organs in the genitourinary system. In this report, an unusual presentation of miliary tuberculosis was presented as GUTB. A 15-year-old girl presented with complaints of severe abdominal pain and dysuria. Read More

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http://dx.doi.org/10.1007/s00467-017-3727-zDOI Listing
April 2018
8 Reads

Omental actinomycosis imitating a foreign body infection.

Z Gastroenterol 2017 Jul 14;55(7):675-678. Epub 2017 Jul 14.

Actinomycosis is a rare chronic disease caused by a group of anaerobic Gram-positive bacteria that colonize the mouth, colon, and urogenital tract. Infection involving the cervicofacial area is the most common clinical presentation, followed by that of the pelvic and thoracic areas. The preoperative diagnosis of abdominal actinomycosis is difficult because the condition can be easily confused with malignancy, tuberculosis, or other inflammatory diseases. Read More

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http://dx.doi.org/10.1055/s-0043-110573DOI Listing
July 2017
33 Reads

Whole Genome Sequencing of Mycobacterium tuberculosis Isolates From Extrapulmonary Sites.

OMICS 2017 07;21(7):413-425

2 Institute of Bioinformatics , International Technology Park, Bangalore, India .

Tuberculosis (TB) remains one of the leading causes of morbidity and mortality worldwide. Extrapulmonary tuberculosis (EPTB) constitutes around 15-20% of TB cases in immunocompetent individuals. Extrapulmonary sites that are affected by TB include bones, lymph nodes, meningitis, pleura, and genitourinary tract. Read More

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http://www.liebertpub.com/doi/10.1089/omi.2017.0070
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http://dx.doi.org/10.1089/omi.2017.0070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436032PMC
July 2017
30 Reads

High incidence of fluoroquinolone resistance and effect of efflux pump inhibitors on moxifloxacin resistance among Mycobacterium tuberculosis isolates causing urinary tract infection in Taiwan.

Int J Antimicrob Agents 2017 Sep 28;50(3):491-495. Epub 2017 Jun 28.

Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

This study explored the prevalence of urinary tract tuberculosis (UTB) and whether efflux pump activation accounts for resistance to moxifloxacin in Taiwan. Of 3034 patients with culture-confirmed TB from 2005-2012, 47 patients (1.5%) with UTB were included in this study. Read More

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http://dx.doi.org/10.1016/j.ijantimicag.2017.04.010DOI Listing
September 2017
19 Reads

Diagnostic accuracy of nucleic acid amplification tests (NAATs) in urine for genitourinary tuberculosis: a systematic review and meta-analysis.

BMC Infect Dis 2017 06 5;17(1):390. Epub 2017 Jun 5.

Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia, Av. Honorio Delgado 430, Urb. Ingeniería, S.M, P, Lima, Perú.

Background: Genitourinary tuberculosis is the third most common form of extrapulmonary tuberculosis. Diagnosis is difficult because of unspecific clinical manifestations and low accuracy of conventional tests. Unfortunately, the delayed diagnosis impacts the urinary tract severely. Read More

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http://dx.doi.org/10.1186/s12879-017-2476-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460328PMC
June 2017
29 Reads

Laparoscopic Reconstruction in Post-Tubercular Urinary Tract Strictures: Technical Challenges.

J Laparoendosc Adv Surg Tech A 2017 Nov 10;27(11):1121-1126. Epub 2017 May 10.

Department of Urology, Institute of Post Graduate Medical Education and Research , Kolkata, India .

Background: Genitourinary tuberculosis still continues to plague developing countries and is a significant cause of morbidity as well as mortality in the developing world. At present, nearly 55% of the patients of genitourinary tuberculosis (GUTB) need surgical management. Owing to the presence of dense adhesions and loss of normal anatomical planes, GUTB was considered to be a contraindication to laparoscopic surgery. Read More

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http://dx.doi.org/10.1089/lap.2016.0609DOI Listing
November 2017
48 Reads

First reported case of fulminant TB with progression of infection from lungs to the genitourinary region.

Rev Inst Med Trop Sao Paulo 2017 04 13;59:e20. Epub 2017 Apr 13.

University of Belgrade, School of Medicine, Belgrade, Serbia.

Although tuberculosis (TB) is a curable disease, it continues to be one of the leading infections associated with death in the world. Extra-pulmonary TB (EPTB) occurs in approximately 10% of the total cases, presenting with lymph nodes, pleura, bone and genitourinary tract as the most common locations. Genitourinary tuberculosis, the second most common EPTB, is very difficult to diagnose unless there is a high index of suspicion. Read More

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http://dx.doi.org/10.1590/S1678-9946201759020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440999PMC
April 2017
23 Reads

Multidetector CT urography in urogenital tuberculosis: use of reformatted images for the assessment of the radiological findings. A pictorial essay.

Abdom Radiol (NY) 2017 09;42(9):2314-2324

Radiology Unit, Department of Diagnostic Medicine and Prevention, St. Orsola-Malpighi Hospital, Via Albertoni, 15, 40138, Bologna, Italy.

Urogenital tuberculosis (UGTB) is the most common form of extrapulmonary TB and is responsible for a destructive inflammation of the renal parenchyma and urinary tract often leading to the loss of kidney function. For these reasons, the early diagnosis of this disease, once considered disappeared in developed countries, is very important to establish a prompt and efficient treatment. However, the subtle and non-specific symptoms, often represented by recurrent and persistent lower urinary tract symptoms, can confound and delay the diagnosis. Read More

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http://dx.doi.org/10.1007/s00261-017-1129-0DOI Listing
September 2017
22 Reads

Gross Hematuria Is More Common in Male and Older Patients with Renal Tuberculosis in China: A Single-Center 15-Year Clinical Experience.

Urol Int 2017 25;99(3):290-296. Epub 2017 Mar 25.

Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, National Urological Cancer Center, Beijing, PR China.

Objectives: This study aimed to investigate the clinical features of renal tuberculosis and identify the age- and gender-related differences.

Methods: A total of 419 patients at the Peking University First Hospital from January 2000 to July 2015 were retrospectively reviewed. Data on demographic characteristics, clinical presentation, complications, laboratory results, radiologic imaging, surgical procedures, and pathology features were collected and compared between genders and 3 different age groups (under 40 years, 41-60, years and over 60 years). Read More

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http://dx.doi.org/10.1159/000464472DOI Listing
June 2018
22 Reads