4,484 results match your criteria Tuberculosis Gastrointestinal


Going Round in Circles with a Multisystemic Disease: A Unique Case of Parasitic Aortitis.

Eur J Case Rep Intern Med 2017 17;4(6):000601. Epub 2017 May 17.

Autoimmune Diseases Unit, Hospital Beatriz Ângelo, Loures, Portugal.

Aortitis results from aortic inflammation, frequent causes being infections and rheumatological disorders. The authors report the case of a 33-year-old black male with recent arterial hypertension, who presented with recurrent abdominal pain, jaundice, anorexia, weight loss and diarrhoea. Laboratory work-up was compatible with inflammatory anaemia and obstructive jaundice, while abdominal imaging revealed a dilated biliary tract, no visible gallstones, cephalic pancreatic globosity and aortic thickening. Read More

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http://dx.doi.org/10.12890/2017_000601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346790PMC

Addison's Disease Caused by Tuberculosis: Diagnostic and Therapeutic Difficulties.

Eur J Case Rep Intern Med 2018 28;5(8):000911. Epub 2018 Aug 28.

Department of Pulmonary Diseases and Tuberculosis, Diakonessenhuis Utrecht, Utrecht, The Netherlands.

Objectives: To demonstrate difficulties in diagnosing and treating Addison's disease caused by tuberculosis.

Materials And Methods: We present a clinical case and review of the literature.

Results: A 62-year-old man presented with gastrointestinal symptoms, weight loss and enlarged adrenal glands. Read More

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http://dx.doi.org/10.12890/2018_000911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346831PMC

When the Diagnosis is a Victim of the Circumstances.

Eur J Case Rep Intern Med 2018 26;5(6):000862. Epub 2018 Jun 26.

Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

Introduction: Haemoptysis is a common symptom which can sometimes mimic gastrointestinal bleeding.

Case Description: We describe the case of a 31-year-old man who presented to the emergency department after an episode of sudden nausea and presumed massive haematemesis. The situation was interpreted as gastrointestinal bleeding but clinical evolution and greater attention to the anamnesis resulted in a diagnosis of pulmonary tuberculosis and the provision of appropriate care. Read More

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http://dx.doi.org/10.12890/2018_000862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346879PMC

Infectious diseases at different stages of migration: an expert review.

J Travel Med 2019 Feb 6. Epub 2019 Feb 6.

JD MacLean Centre for Tropical Diseases at McGill, McGill University Health Centre, McGill University.

Background: Human migration is increasing in magnitude and scope. The majority of migrants arriving in high income countries originate from countries with a high prevalence of infectious diseases. The risk and burden of infectious diseases are not equally distributed among migrant groups and varies with migration stage. Read More

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http://dx.doi.org/10.1093/jtm/taz007DOI Listing
February 2019
4 Reads

Esophageal Stricture Caused by in a Patient with No Apparent Predisposing Factors.

Case Rep Gastrointest Med 2019 2;2019:7182976. Epub 2019 Jan 2.

Division of Gastroenterology and Hepatobiliary Diseases, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, 11215, USA.

species are Gram positive anaerobic or microaerophilic bacteria that are part of the human flora in the oropharyngeal, gastrointestinal, and genitourinary tract. In the presence of a mucosal injury, they can become pathogenic and infect the underlying tissue without respect for tissue planes, leading to abscesses, fistulas, and sinus tracts. Through contiguous and hematogenous spread, virtually any organ can become infected. Read More

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https://www.hindawi.com/journals/crigm/2019/7182976/
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http://dx.doi.org/10.1155/2019/7182976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334373PMC
January 2019
2 Reads

Protective Features of Autophagy in Pulmonary Infection and Inflammatory Diseases.

Cells 2019 Feb 3;8(2). Epub 2019 Feb 3.

Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND 58203, USA.

Autophagy is a highly conserved catabolic process involving autolysosomal degradation of cellular components, including protein aggregates, damaged organelles (such as mitochondria, endoplasmic reticulum, and others), as well as various pathogens. Thus, the autophagy pathway represents a major adaptive response for the maintenance of cellular and tissue homeostasis in response to numerous cellular stressors. A growing body of evidence suggests that autophagy is closely associated with diverse human diseases. Read More

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http://dx.doi.org/10.3390/cells8020123DOI Listing
February 2019
2 Reads

[A Case of Sigmoid Colon Cancer Identified by Gastric Perforation].

Gan To Kagaku Ryoho 2018 Dec;45(13):2384-2386

Dept. of Surgery, Tokyo Women's Medical University Medical Center East.

We report a case of sigmoid colon cancer that was incidentally found using CT that was performed for upper abdominal pain. An 83-year-old man with a long history of lung tuberculosis and idiopathic pulmonary fibrosis presented with upper abdominal pain. CT findings revealed free gas around the stomach. Read More

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December 2018
2 Reads

Delayed Diagnosis of Hereditary Angioedema with C1-inhibitor Deficiency in Iranian Children and Adolescents.

Pediatr Allergy Immunol 2019 Jan 28. Epub 2019 Jan 28.

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Hereditary angioedema is an autosomal dominant deficiency of C1-inhibitor (C1-INH-HAE). This rare but potentially fatal disease gives rise to episodes of bradykinin-mediated edema in face, trunk, extremities, genitalia, gastrointestinal tract and upper airway. This leads to severe outcomes including asphyxiation, unnecessary emergency abdominal surgeries, and a considerably diminished quality of life in addition to high economic burden for the health care system. Read More

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http://doi.wiley.com/10.1111/pai.13028
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http://dx.doi.org/10.1111/pai.13028DOI Listing
January 2019
2 Reads
3.397 Impact Factor

Gastric Tuberculosis Presenting as a Subepithelial Mass: A Rare Cause of Gastrointestinal Bleeding.

Korean J Gastroenterol 2018 Dec;72(6):304-307

Department of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Gastric tuberculosis accounts for approximately 2% of all cases of gastrointestinal tuberculosis. Diagnosis of gastric tuberculosis is challenging because it can present with various clinical, endoscopic, and radiologic features. Tuberculosis manifesting as a gastric subepithelial tumor is exceedingly rare; only several dozen cases have been reported. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2018.72
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http://dx.doi.org/10.4166/kjg.2018.72.6.304DOI Listing
December 2018
3 Reads

Phenotypical and functional evaluation of dendritic cells after exosomal delivery of miRNA-155.

Life Sci 2019 Feb 6;219:152-162. Epub 2019 Jan 6.

Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Aims: The clinical efficiency of dendritic cell (DC) therapy needs to be improved. Exosomes, as membrane nano-vesicles, carry bio-macromolecules and play essential roles in intercellular crosstalk. Here, it is proposed that tumor cell-derived exosomes could function as vehicles to deliver exogenous miRNA-155 into DCs, for simultaneous miRNA delivery and antigen priming of DCs. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.01.005DOI Listing
February 2019
2.702 Impact Factor

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection.

Front Immunol 2018 14;9:2893. Epub 2018 Dec 14.

Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.

Soil-transmitted helminths and frequently coincide geographically and it is hypothesized that gastrointestinal helminth infection may exacerbate tuberculosis (TB) disease by suppression of Th1 and Th17 responses. However, few studies have focused on latent TB infection (LTBI), which predominates globally. We performed a large observational study of healthy adults migrating from Nepal to the UK ( = 645). Read More

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http://dx.doi.org/10.3389/fimmu.2018.02893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302045PMC
December 2018

Case report: systemic tuberculosis caused by Mycobacterium bovis in a cat.

BMC Vet Res 2019 Jan 5;15(1). Epub 2019 Jan 5.

Department of Virology, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey.

Background: The diagnosis of previous cases of feline tuberculosis in Turkey has been made based solely on pathological changes without isolation of the causative agent. This case report details the first case of feline tuberculosis in Turkey for which the causative agent (Mycobacterium bovis) was confirmed with microbiological isolation, morphological evaluation, molecular (PCR) characterization and antibiotic sensitivity.

Case Presentation: Systemic tuberculosis was diagnosed via postmortem examination of a 5-year-old stray male cat. Read More

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http://dx.doi.org/10.1186/s12917-018-1759-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321719PMC
January 2019
3 Reads

Isolated pancreatic tuberculosis with elevated CA 19-9 levels masquerading as a malignancy: A rare case report and literature review.

Medicine (Baltimore) 2018 Dec;97(52):e13858

Department of Hepatobiliary Surgery, Weihai Central Hospital, Weihai, Shandong Province, People's Republic of China.

Rationale: Primary pancreatic tuberculosis is extremely rare, it presents with non-specific clinical symptoms and imaging features; it may be falsely identified as a malignancy of the pancreas.

Patient Concerns: A 41-year-old male with no history of tuberculosis presented to our hospital with a 2-week history of jaundice.

Diagnoses: Abdominal computed tomography (CT) showed a heterogeneous irregular hypodense mass in the head of the pancreas causing dilatation of the common bile duct (CBD), and it was enhanced after infusion of contrast material. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812280-0006
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http://dx.doi.org/10.1097/MD.0000000000013858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314711PMC
December 2018
2 Reads

Impact of Mycobacterium tuberculosis complex lineages as a determinant of disease phenotypes from an immigrant rich moderate tuberculosis burden country.

Respir Res 2018 Dec 27;19(1):259. Epub 2018 Dec 27.

Department of Infection and Immunity, MBC-03, King Faisal Specialist Hospital and Research Centre, Post Box # 3354, Riyadh, 11211, Saudi Arabia.

Background: Growing evidences suggested that the Mycobacterium tuberculosis complex (MTBC) lineages can determine the clinical outcome of pulmonary and extra-pulmonary tuberculosis. However, limited data only available revealing such association of bacterial genotypes and clinical phenotypes from immigrant rich countries.

Methods: A multicenter study has been carried out on a collection of 2092 (1003 extrapulmonary and 1089 pulmonary) MTBC isolates. Read More

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http://dx.doi.org/10.1186/s12931-018-0966-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307224PMC
December 2018

Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience.

BMC Infect Dis 2018 Dec 27;18(1):699. Epub 2018 Dec 27.

Department of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, 15, Jinju-daero 816 beon-gil, Jinju-si, Gyeongnam, 52727, Republic of Korea.

Background: Abdominal tuberculosis (TB) is an uncommon form of infection with Mycobacterium tuberculosis in Korea. In this study, we aimed to highlight the clinical features, diagnostic methods, and outcomes of abdominal TB over 12 years in Southeastern Korea.

Methods: A total of 139 patients diagnosed as having abdominal TB who received anti-TB medication from January 2005 to June 2016 were reviewed. Read More

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http://dx.doi.org/10.1186/s12879-018-3635-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307147PMC
December 2018
2 Reads

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report.

BMC Infect Dis 2018 Dec 27;18(1):693. Epub 2018 Dec 27.

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.

Background: Highly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.

Case Presentation: A 35-year-old male with a history of fever and back pain. Read More

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http://dx.doi.org/10.1186/s12879-018-3573-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307234PMC
December 2018
4 Reads

General contextual effects on neglected tropical disease risk in rural Kenya.

PLoS Negl Trop Dis 2018 12 21;12(12):e0007016. Epub 2018 Dec 21.

International Livestock Research Institute, Nairobi, Kenya.

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-based studies of NTD risk. We describe a general contextual analysis that uses multi-level models to partition and quantify variation in individual NTD risk at multiple grouping levels in rural Kenya. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007016
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http://dx.doi.org/10.1371/journal.pntd.0007016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342328PMC
December 2018
6 Reads

Anorectal tuberculosis as a chronic rectal mass mimicking rectal prolapse in a child-a case report.

Ann Med Surg (Lond) 2018 Dec 12;36:264-266. Epub 2018 Sep 12.

Division of Infectious Disease, Immunology and International Medicine, University of Illinois College of Medicine at Chicago, Chicago, USA.

Tuberculosis of the colon commonly involves the ascending,transverse, or sigmoid colon while rectal involvement in tuberculosis is uncommon and poorly characterized. We report a six-year-old male from Nepal who presented with abdominal pain and difficulty passing stool for two years. On per rectal examination, palpation revealed a circumferential rectal mass. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287574PMC
December 2018

Tuberculosis presenting as a pancreatic cystic neoplasm.

BMJ Case Rep 2018 Dec 9;11(1). Epub 2018 Dec 9.

Department of Surgery, Amsterdam UMC, University of Amsterdam, The Netherlands.

A 33-year-old Thai born woman was referred to our tertiary referral hospital with back and epigastric pain. Investigations included abdominal ultrasound and CT scan of the abdomen which demonstrated a 3 cm cystic lesion in the head of the pancreas, most likely a mucinous cystadenoma. Because of its malignant potential resection was advised. Read More

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http://dx.doi.org/10.1136/bcr-2018-225983DOI Listing
December 2018
2 Reads

Evaluation of microsatellite instability in tumor and tumor marginal samples of sporadic colorectal cancer using mononucleotide markers.

EXCLI J 2018 24;17:945-951. Epub 2018 Sep 24.

Department of Medical Genetics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Microsatellite instability (MSI) is a unique molecular alteration that is due to a defective DNA mismatch repair (MMR) system. Approximately, 15-20 % of sporadic colorectal cancers (CRC) display MSI. Determination of MSI status in CRC has prognostic and predictive implications. Read More

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http://dx.doi.org/10.17179/excli2018-1455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295640PMC
September 2018
0.857 Impact Factor

Tuberculous peritonitis diagnosed using laparoscopy with assistance of a central venous catheter.

Exp Ther Med 2018 Dec 12;16(6):5265-5271. Epub 2018 Oct 12.

Department of Gastroenterology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, Shenzhen, Guangdong 518020, P.R. China.

Laparoscopy with peritoneal biopsy is a tool for rapid and accurate diagnosis of tuberculous peritonitis (TBP). However, laparoscopic procedures are not risk-free; complications include injuries to the gastrointestinal tract and major blood vessels. The purpose of the present study was to introduce a novel method for safe and straightforward laparoscopic diagnosis of TBP. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.6854
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http://dx.doi.org/10.3892/etm.2018.6854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257215PMC
December 2018
6 Reads

An elderly man with gastric cancer, Saint's triad and Heyde's syndrome.

Rev Gastroenterol Peru 2018 Jul-Sep;38(3):289-292

Armed Forces Hospital. Brasília-DF, Brazil.

This case study describes a 71-year-old man with signet-ring cell gastric adenocarcinoma and malignant sigmoidal polyp; and typical features of Saint's triad and Heyde syndrome. He had digestive bleeding, two types of hernia, diverticulosis, arterial hypertension, malignant polyp, and antecedent of smoking, lung tuberculosis, and surgical correction of aortic valve stenosis. There is a hypothetical inverse relationship between herniosis and development of malignancy; however, the patient herein described presented gastric and sigmoidal cancers. Read More

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December 2018
2 Reads

Primary Appendicular Malignancy Presenting as Abdominal Wall Abscess with Secondary Tuberculosis Infection: an Interesting Case Report.

Indian J Surg Oncol 2018 Dec 7;9(4):613-617. Epub 2018 Aug 7.

Parvarish Nursing Home, Andheri, Mumbai, Maharashtra India.

Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Read More

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http://dx.doi.org/10.1007/s13193-018-0804-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265167PMC
December 2018
3 Reads

Esophageal tuberculosis: Uncommon of common.

JGH Open 2018 Apr 2;2(2):34-38. Epub 2018 Apr 2.

Department of Gastroenterology GB Pant Hospital New Delhi India.

Background And Aim: Esophageal involvement in tuberculosis (TB) is rare and is usually secondary. Data on esophageal TB are scarce. We aimed to analyze clinical and endoscopic features and outcomes of treatment in esophageal TB. Read More

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http://doi.wiley.com/10.1002/jgh3.12043
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http://dx.doi.org/10.1002/jgh3.12043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207044PMC
April 2018
8 Reads

Does long sleep duration increase risk of metabolic syndrome in Azar cohort study population?

Health Promot Perspect 2018 27;8(4):290-295. Epub 2018 Oct 27.

Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

We decided to assess the correlation between metabolic syndrome (MetS) risks,sleep and napping duration in Azar cohort population according to the increasing incidence of MetS in the world and inconsistence results about sleep duration and MetS. In this cross-sectional study, MetS and sleep habits of 14916 subjects (35-70 years old) who inhabited in Shabestar city were determined by ATPIII and Pittsburg questionnaire respectively. Inclusion criteria were subjects with 35-70 years old and living in Shabestar for at least 9 months of the year. Read More

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http://dx.doi.org/10.15171/hpp.2018.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249496PMC
October 2018
7 Reads

Heterologous Boost Following Reduces the Late Persistent, Rather Than the Early Stage of Intranasal Tuberculosis Challenge Infection.

Front Immunol 2018 30;9:2439. Epub 2018 Oct 30.

Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Adults are the leading population affected by tuberculosis (TB) epidemic and death. Developing an effective vaccine against adult TB is urgently needed. Bacillus Calmette-Guerin (BCG) prime-heterologous boost strategy has been explored extensively to protect adults against primary TB infection, but the majority of experimental regimens have not improved the protection primed by the BCG vaccine. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02439
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http://dx.doi.org/10.3389/fimmu.2018.02439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218689PMC
October 2018
10 Reads

[Gastric tuberculosis in an elderly patient:a case report].

Nihon Shokakibyo Gakkai Zasshi 2018 ;115(11):985-995

Department of Gastroenterology, Toyohashi Municipal Hospital.

A woman in her 70s presented to our hospital with epigastric pain, back pain, and weight loss. Esophagogastroduodenoscopy was performed, and numerous protuberances, which were suspected to be submucosal tumors, were found at the gastric corpus. The patient was diagnosed with gastric tuberculosis based on the biopsy results of these protuberances. Read More

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https://www.jstage.jst.go.jp/article/nisshoshi/115/11/115_98
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http://dx.doi.org/10.11405/nisshoshi.115.985DOI Listing
January 2018
6 Reads

Hepatitis C virus, directly acting antivirals and Guillain-Barré syndrome.

Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1237-1239

Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.

Guillain-Barré syndrome (GBS) has been associated with both infective and noninfective etiologies. It is usually preceded by acute gastrointestinal or respiratory infections. We report an unusual case of GBS in a hepatitis C virus-positive hemodialysis (HD)-dependent patient who was being treated with sofosbuvir and daclatasvir along with antitubercular drugs for pulmonary tuberculosis. Read More

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http://www.sjkdt.org/text.asp?2018/29/5/1237/243969
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http://dx.doi.org/10.4103/1319-2442.243969DOI Listing
November 2018
5 Reads

Acquired zinc deficiency in a renal transplant recipient with gastrointestinal tuberculosis responding promptly to oral correction.

Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1199-1202

Department of Dermatology, Jaslok Hospital and Research Center, Mumbai, Maharashtra, India.

Zinc deficiency is an uncommon condition, known to occur in two forms: inherited type, known as Acrodermatitis enteropathies and the acquired type. Cutaneous clinical manifestations observed include characteristic dermatitis on acral, periorificial, and anogenital areas through an unknown mechanism. The patient had a combination of causes which lead to a state of zinc deficiency. Read More

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http://www.sjkdt.org/text.asp?2018/29/5/1199/243962
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http://dx.doi.org/10.4103/1319-2442.243962DOI Listing
November 2018
14 Reads

Epidemiology and Outcomes of Nontyphoidal Bacteremias from England, 2004 to 2015.

J Clin Microbiol 2019 Jan 2;57(1). Epub 2019 Jan 2.

Tuberculosis, Acute Respiratory, Gastrointestinal, Emerging/Zoonotic Infections, and Travel and Migrant Health Division, National Infection Service, Public Health England, London, United Kingdom

Nontyphoidal (NTS) bacteremia causes hospitalization and high morbidity and mortality. We linked Gastrointestinal Bacteria Reference Unit (GBRU) data to the Hospital Episode Statistics (HES) data set to study the trends and outcomes of NTS bacteremias in England between 2004 and 2015. All confirmed NTS isolates from blood from England submitted to GBRU between 1 January 2004 and 31 December 2015 were deterministically linked to HES records. Read More

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http://dx.doi.org/10.1128/JCM.01189-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322475PMC
January 2019
5 Reads

Efficacy of acupressure to prevent adverse reactions to anti-tuberculosis drugs: Randomized controlled trials.

J Adv Nurs 2018 Oct 29. Epub 2018 Oct 29.

Institute of Clinical Nursing, National Yang-Ming University, Taipei, Taiwan.

Aim: To determine whether acupressure can prevent or relieve the adverse drug reactions (ADRs) of anti-tuberculosis drugs.

Background: People receiving drug treatment for TB often experience ADRs that may cause them to stop taking their medication. Acupressure is a form of traditional Chinese medicine that can be applied to alleviate or prevent disease symptoms. Read More

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http://doi.wiley.com/10.1111/jan.13881
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http://dx.doi.org/10.1111/jan.13881DOI Listing
October 2018
7 Reads

Cutaneous Infection With Mycobacterium haemophilum in an Immunocompromised Patient.

Iran J Kidney Dis 2018 Oct;12(5):312-314

Infectious Diseases and Tropical Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Mycobacterium haemophilum is a fastidious nontuberculosis Mycobacterium that must be considered in the differential diagnosis of infections in immunocompromised patients. Mycobacterium haemophilum typically is a pathogen of the cutaneous or subcutaneous tissue and also presents as septic arthritis, osteomyelitis, pulmonary disease, and lymphadenitis. We report a 32-year-old man with past medical history of kidney transplantation, endocarditis, gastrointestinal bleeding, and hypertension, complaining of multiple painful nodular lesions since 3 months earlier. Read More

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October 2018
14 Reads

Histochemistry in the diagnosis of non-neoplastic gastrointestinal disorders.

Semin Diagn Pathol 2018 Nov 16;35(6):370-380. Epub 2018 Oct 16.

Department of Pathology, St. Jude Medical Center, Fullerton, CA 92835, United States. Electronic address:

The alimentary tract serves as host to a large number of diseases. In the non-neoplastic group of disorders, conventional histochemistry continues to play an important diagnostic role. It is particularly important in recognizing specific infectious diseases, such as Helicobacter gastritis, Whipple disease, intestinal tuberculosis and other forms of mycobacteriosis, malakoplakia, intestinal spirochetosis, fungal enteritides, amebiasis, cryptosporidiosis, isosporiasis, and microsporidiosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07402570183009
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http://dx.doi.org/10.1053/j.semdp.2018.10.002DOI Listing
November 2018
21 Reads

Diagnostic point-of-care ultrasound (POCUS) for gastrointestinal pathology: state of the art from basics to advanced.

World J Emerg Surg 2018 15;13:47. Epub 2018 Oct 15.

2Department of Internal Medicine, College of Medicine and Health Sciences, UAE University, Al-Ain, 17666 United Arab Emirates.

The use of point-of-care ultrasound (POCUS) by non-radiologists has dramatically increased. POCUS is completely different from the routine radiological studies. POCUS is a Physiological, On spot, extension of the Clinical examination, that is Unique, and Safe. Read More

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https://wjes.biomedcentral.com/articles/10.1186/s13017-018-0
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http://dx.doi.org/10.1186/s13017-018-0209-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190544PMC
January 2019
10 Reads

Severe strongyloidiasis and systemic vasculitis: comorbidity, association or both? Case-based review.

Rheumatol Int 2018 Dec 23;38(12):2315-2321. Epub 2018 Oct 23.

Clinic of Allergology and Immunology, Clinical Center of Serbia, Belgrade, Serbia.

A possible association between strongyloidiasis and systemic vasculitis is rarely reported in the literature. We report the case of a patient with severe strongyloidiasis and an angiographic finding consistent with polyarteritis nodosa. Diagnosis of strongyloidiasis was made by finding of larvae and adult parasites in samples of the upper gastrointestinal tract mucosa and stool. Read More

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http://link.springer.com/10.1007/s00296-018-4178-y
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http://dx.doi.org/10.1007/s00296-018-4178-yDOI Listing
December 2018
13 Reads

[Clinical analysis of 50 cases of serous cavity effusion related with paragonimiasis].

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi 2018 Aug;30(4):452-454

Department of Respiratory Medicine, Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.

Objective: To analyze the clinical characteristics of serous cavity effusion related with paragonimiasis, so as to improve the physician's ability of the clinical diagnosis and treatment.

Methods: The clinical data of 50 cases of serous cavity effusion related with paragonimiasis diagnosed in a hospital in recent 3 years were collected and retrospectively analyzed.

Results: Among the 50 patients, there were 35 males and 15 females, and 35 children and 15 adults. Read More

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http://dx.doi.org/10.16250/j.32.1374.2017243DOI Listing
August 2018
11 Reads

Evaluation of treatment outcome and adverse drug reaction of directly observed treatment (DOT) plus regimen in multidrug-resistant tuberculosis (MDR-TB) patients at district tuberculosis centre Rajkot.

Perspect Clin Res 2018 Oct-Dec;9(4):165-169

Department of Pharmacology, P.D.U. Government Medical College, Rajkot, Gujarat, India.

Background: The emergence of drug-resistant mycobacteria becomes a significant public health problem globally creating an obstacle to effective tuberculosis (TB) control. Gujarat, Maharashtra, and Andhra Pradesh DRS survey estimated that the proportion of multidrug-resistant TB (MDR-TB) is 2.1% (in new TB cases) and 15% (in previously treated cases). Read More

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http://dx.doi.org/10.4103/picr.PICR_165_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176692PMC
October 2018
1 Read

Proof of concept in utilizing in-trans surface display system of Lactobacillus plantarum as mucosal tuberculosis vaccine via oral administration in mice.

BMC Biotechnol 2018 Oct 11;18(1):63. Epub 2018 Oct 11.

Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor Darul Ehsan, Malaysia.

Background: Tuberculosis is one of the most common and deadliest infectious diseases worldwide affecting almost a third of the world's population. Although this disease is being prevented and controlled by the Bacille Calmette Guérin (BCG) vaccine, the protective efficacy is highly variable and substandard (0-80%) in adults. Therefore, novel and effective tuberculosis vaccine that can overcome the limitations from BCG vaccine need to be developed. Read More

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https://bmcbiotechnol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12896-018-0461-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182793PMC
October 2018
2 Reads

Crohn's disease with positive Ziehl-Neelsen stain: Three case reports.

Niger J Clin Pract 2018 Oct;21(10):1387-1390

Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Because of the similarity of the clinical symptoms, endoscopic, and pathological features, the differential diagnosis between Crohn's disease (CD) and intestinal tuberculosis (ITB) remains difficult, especially in a high-incidence area of tuberculosis (TB). Here we reported three patients with positive Ziehl-Neelsen stain in endoscopic mucosal biopsy specimens. They had a poor response to anti-TB therapy but a good response to immunosuppresses, infliximab, or surgery, and were finally diagnosed as CD. Read More

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http://dx.doi.org/10.4103/njcp.njcp_31_18DOI Listing
October 2018
2 Reads

Tuberculosis in dialysis: Clinical spectrum and outcome from an endemic region.

Authors:
Sanjay Vikrant

Hemodial Int 2018 Oct 5. Epub 2018 Oct 5.

Department of Nephrology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

Introduction: Tuberculosis (TB) is a significant health problem in developing countries. There are limited data on TB among end stage renal disease (ESRD) patients on maintenance dialysis in India. Clinical profile and outcome of TB in dialysis were studied. Read More

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http://doi.wiley.com/10.1111/hdi.12693
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http://dx.doi.org/10.1111/hdi.12693DOI Listing
October 2018
15 Reads

Role of gut inhabitants on vectorial capacity of mosquitoes.

J Vector Borne Dis 2018 Apr-Jun;55(2):69-78

Communicable Disease Research Laboratory, Department of Zoology, St. Joseph's College, Irinjalakuda, Kerala, India.

Mosquito-borne diseases are spreading at an alarming rate. Globally millions of deaths occur due to the diseases transmitted by mosquitoes, next to AIDS and tuberculosis. Several methods have been used to control these vectors and the diseases caused by them. Read More

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http://www.jvbd.org/text.asp?2018/55/2/69/242567
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http://dx.doi.org/10.4103/0972-9062.242567DOI Listing
December 2018
2 Reads

Nanoencapsulation of Bacteriophages in Liposomes Prepared Using Microfluidic Hydrodynamic Flow Focusing.

Front Microbiol 2018 12;9:2172. Epub 2018 Sep 12.

Chemical Engineering Department, Loughborough University, Loughborough, United Kingdom.

Increasing antibiotic resistance in pathogenic microorganisms has led to renewed interest in bacteriophage therapy in both humans and animals. A "Trojan Horse" approach utilizing liposome encapsulated phages may facilitate access to phagocytic cells infected with intracellular pathogens residing therein, e.g. Read More

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http://dx.doi.org/10.3389/fmicb.2018.02172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6144953PMC
September 2018
2 Reads

Antibiotics for treating scrub typhus.

Cochrane Database Syst Rev 2018 09 24;9:CD002150. Epub 2018 Sep 24.

Department of Biomedical Informatics and Medical Statistics, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Background: Scrub typhus, an important cause of acute fever in Asia, is caused by Orientia tsutsugamushi, an obligate intracellular bacterium. Antibiotics currently used to treat scrub typhus include tetracyclines, chloramphenicol, macrolides, and rifampicin.

Objectives: To assess and compare the effects of different antibiotic regimens for treatment of scrub typhus. Read More

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http://dx.doi.org/10.1002/14651858.CD002150.pub2DOI Listing
September 2018
11 Reads

An autopsy case of TAFRO syndrome with membranoproliferative glomerulonephritis-like lesions.

CEN Case Rep 2019 Feb 22;8(1):48-54. Epub 2018 Sep 22.

Department of Pathology, Kitasato University School of Medicine, Sagamihara, Japan.

TAFRO syndrome (thrombocytopenia, anasarca, myelofibrosis, renal dysfunction, and organomegaly) is an atypical manifestation of multicentric Castleman's disease. Although overproduction of interleukin-6, vascular endothelial growth factor, and other cytokines may partially explain the pathophysiology of this rare syndrome, the precise mechanisms underlying the renal dysfunction associated with the condition remain unclear. Here, we describe a case of a 69-year-old male with TAFRO syndrome. Read More

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http://dx.doi.org/10.1007/s13730-018-0363-9DOI Listing
February 2019
3 Reads

Human β-defensin 1 update: Potential clinical applications of the restless warrior.

Int J Biochem Cell Biol 2018 Nov 17;104:133-137. Epub 2018 Sep 17.

Personalized Medicine National Laboratory (LAMPER), Medical and Pharmaceutical Biotechnology Unit, Research Center of Technology and Design Assistance of Jalisco State (CIATEJ), National Council of Science and Technology (CONACYT), Av. Normalistas 800, Col. Colinas de la Normal, Guadalajara, Mexico. Electronic address:

Human β-defensin 1 (hBD-1) is a multifaceted antimicrobial peptide being a tumour suppressor and, depending on call of duty, capable of inducing self-nets and neutrophil extracellular traps (NETs) to capture and/or kill bacteria, participates in inflammatory responses in chronic diseases including hBD-3 upregulation and also capable of up/downregulation in the presence of certain species of Lactobacillus sp. Thus, is regulated by host microbiota. Alleles, genotypes and/or altered gene expression of its coding gene, DEFB1, have been associated with several human diseases/conditions ranging from metabolic/chronic (e. Read More

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http://dx.doi.org/10.1016/j.biocel.2018.09.007DOI Listing
November 2018
1 Read

Atypical serious hematochezia and rare imaging feature in gastrointestinal tuberculosis.

Clin J Gastroenterol 2018 Sep 19. Epub 2018 Sep 19.

Department of gastroenterology, Peking University First Hospital, No. 7th, Xishiku Street, Xicheng District, Beijing, 100034, China.

A young patient had serious hematochezia for nearly 2 months without obvious cause. Abdominal CT images showed rare features such as serious hemorrhage and multiple miliary nodules in the small bowel. The colonoscopy showed multiple lymphoid follicles in the terminal ileum. Read More

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http://dx.doi.org/10.1007/s12328-018-0910-0DOI Listing
September 2018
2 Reads

Rifampicin Alters Metformin Plasma Exposure but Not Blood Glucose Levels in Diabetic Tuberculosis Patients.

Clin Pharmacol Ther 2018 Sep 17. Epub 2018 Sep 17.

Department of Pharmacology and Therapy, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.

The pharmacokinetic (PK) and clinical implications of combining metformin with rifampicin are relevant to increasing numbers of patients with diabetic tuberculosis (TB) across the world and are yet unclear. We assessed the impact of rifampicin on metformin PKs and its glucose-lowering effect in patients with diabetic TB by measuring plasma metformin and blood glucose during and after TB treatment. Rifampicin increased metformin exposure: plasma area under the plasma concentration-time curve from time point 0 to the end of the dosing interval (AUC ) and peak plasma concentration (C ) geometric mean ratio (GMR; during vs. Read More

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http://dx.doi.org/10.1002/cpt.1232DOI Listing
September 2018
8 Reads

Safety Profile of Baricitinib in Patients with Active Rheumatoid Arthritis with over 2 Years Median Time in Treatment.

J Rheumatol 2019 Jan 15;46(1):7-18. Epub 2018 Sep 15.

From the Division of Rheumatology, Department of Medicine, Medical University of Vienna, Vienna, Austria; Division of Immunology and Rheumatology, Stanford University Medical Center, Palo Alto, California, USA; Division of Rheumatology, Department of Internal Medicine, Keio University, Tokyo, Japan; Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana, USA; Lilly Research Laboratories, Eli Lilly and Co., Kobe, Japan; Oregon Health Sciences University, Portland, Oregon, USA.

Objective: Baricitinib is an oral, once-daily selective Janus kinase (JAK1/JAK2) inhibitor for adults with moderately to severely active rheumatoid arthritis (RA). We evaluated baricitinib's safety profile through 288 weeks (up to September 1, 2016) with an integrated database [8 phase III/II/Ib trials, 1 longterm extension (LTE)].

Methods: The "all-bari-RA" group included patients who received any baricitinib dose. Read More

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.171361
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http://dx.doi.org/10.3899/jrheum.171361DOI Listing
January 2019
20 Reads

Predictors for false-negative QuantiFERON-TB Gold assay results in patients with extrapulmonary tuberculosis.

BMC Infect Dis 2018 Sep 10;18(1):457. Epub 2018 Sep 10.

Department of Laboratory medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Backgrounds: Extrapulmonary tuberculosis (EPTB) is a heterogeneous disease, and diagnosis is sometimes difficult. We investigated the diagnostic performance of the QuantiFERON-TB Gold assay (QFT-GIT) according to sites of EPTB and predictors for false-negative QFT-GIT results.

Methods: A total of 2176 patients were registered with active TB from January 2012 to December 2016 in Seoul St. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
Publisher Site
http://dx.doi.org/10.1186/s12879-018-3344-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131843PMC
September 2018
8 Reads

Upper lip bite test for prediction of difficult airway: A systematic review.

Pak J Med Sci 2018 Jul-Aug;34(4):1019-1023

Sarvin Sanaie Assistant Professor, Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Background And Objective: Upper lip bite test (ULBT) is one of the various bedside tests used for prediction of difficult laryngoscopic intubation. However, its usefulness is not still very clear, and there is controversy regarding its accuracy. The aim of this systematic review was to determine the accuracy of the ULBT for predicting difficult airway including difficult laryngoscopy or difficult tracheal intubation. Read More

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http://dx.doi.org/10.12669/pjms.344.15364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115582PMC
September 2018
8 Reads