4,519 results match your criteria Tuberculosis Gastrointestinal


Intestinal Tuberculosis: A Rare Case of Massive Gastrointestinal Bleed in a Post-Renal Transplant Recipient.

Indian J Nephrol 2019 Mar-Apr;29(2):132-134

Department of Nephrology, PGIMER, Chandigarh, India.

Massive rectal bleeding is an uncommon presentation of ileal tuberculosis (TB). We report an uncommon cause of anemia in a post-renal transplant patient due to massive lower gastrointestinal (LGI) bleed. The index case had a normal upper and LGI endoscopy, but the technetium labeled red blood cell scan showed active bleeding from terminal ileum and caecum. Read More

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http://dx.doi.org/10.4103/ijn.IJN_360_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440334PMC

Expression and clinical significance of B and T lymphocyte attenuator on CD4 and CD8 T cells from patients with pulmonary tuberculosis.

Indian J Pathol Microbiol 2019 Apr-Jun;62(2):232-238

Department of Tuberculosis, The Affiliated Infectious Hospital of Soochow University, Suzhou, China.

Background: As an immune checkpoint, upregulation of B and T lymphocyte attenuator (BTLA) contributes to T-cell exhaustion in chronic infection. However, the characteristics of BTLA on T cells of patients with pulmonary tuberculosis (PTB) are still uncovered.

Aims: The aim of the study was to elucidate the dynamics and clinical significance of BTLA expression on circulating CD4 and CD8 T cells of PTB patients. Read More

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http://dx.doi.org/10.4103/IJPM.IJPM_727_17DOI Listing
April 2019
1 Read

Common and uncommon imaging features of abdominal tuberculosis.

J Med Imaging Radiat Oncol 2019 Apr 1. Epub 2019 Apr 1.

Department of Gastroenterology and Radiodiagnosis and Imaging, Postgraduate Institute of Medical Imaging and Research (PGIMER), Chandigarh, India.

Despite the advances in the medical care, tuberculosis (TB) still remains an important health problem. This is particularly relevant to the developing countries as well as the immunocompromised population in the developed world. Multidrug resistance poses another challenge and may be responsible for increasing incidence of TB, to some extent. Read More

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http://dx.doi.org/10.1111/1754-9485.12874DOI Listing
April 2019
1 Read

Home-based Anti-Tuberculosis Treatment Adverse Reactions (HATTAR) study: a protocol for a prospective observational study.

BMJ Open 2019 Mar 30;9(3):e027321. Epub 2019 Mar 30.

Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China.

Introduction: Tuberculosis (TB) continues to be an important public health problem throughout much of the world. Drug treatment is the only effective treatment method, but adverse drug events (ADEs) and adverse drug reactions (ADRs) can affect medication adherence. As the number of drug-resistant TB patients and the number of anti-TB drugs have increased, it is necessary to explore the risk factors for ADEs/ADRs to reduce their occurrence. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-027321DOI Listing
March 2019
2 Reads

Demographic risk factors for extra-pulmonary tuberculosis among adolescents and adults in Saudi Arabia.

PLoS One 2019 27;14(3):e0213846. Epub 2019 Mar 27.

Department of Infection and Immunity, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.

Despite low infectious potential of extrapulmonary tuberculosis (EPTB), it poses significant clinical challenges in terms of diagnosis and treatment monitoring. Understanding the main demographical risk factors for disease characteristics of EPTB plays a crucial role in speeding up diagnosis process and improving overall clinical experience. The aim of this study was to investigate the main demographical and clinical risk factors for EPTB among adults and adolescents for the first time in Saudi Arabia. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436801PMC
March 2019
3.234 Impact Factor

Evaluation of Adverse Reactions Induced by Anti-Tuberculosis Drugs in Hospital Pulau Pinang.

Malays J Med Sci 2018 Sep 30;25(5):103-114. Epub 2018 Oct 30.

Respiratory Department, Hospital Pulau Pinang, Jalan Residensi, 10990 Georgetown, Pulau Pinang, Malaysia.

Background: The use of multi-drug regimens in tuberculosis (TB) treatment has been associated with undesirable adverse drug reactions (ADRs). This study aims to assess the incidence and impact of ADRs on TB treatment in Hospital Pulau Pinang.

Methods: This cross-sectional study was conducted via retrospective review of outpatients' medical records. Read More

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http://dx.doi.org/10.21315/mjms2018.25.5.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419878PMC
September 2018

Common Infections and Target Organs Associated with Chronic Granulomatous Disease in Iran.

Int Arch Allergy Immunol 2019 Mar 22:1-12. Epub 2019 Mar 22.

Cell and Molecular Biology Group, Airways Disease Section, National Heart and Lung Institute, Imperial College London, London, United Kingdom,

Recurrent severe bacterial and fungal infections are characteristic features of the rare genetic immunodeficiency disorder chronic granulomatous disease (CGD). The disease usually manifests within the first years of life with an incidence of 1 in approximately 200,000 live births. The incidence is higher in Iran and Morocco where it reaches 1. Read More

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http://dx.doi.org/10.1159/000496181DOI Listing
March 2019
1 Read
2.673 Impact Factor

Multi-omics comparisons of p-aminosalicylic acid (PAS) resistance in folC mutated and un-mutated Mycobacterium tuberculosis strains.

Emerg Microbes Infect 2019 ;8(1):248-261

a Center for Tuberculosis Control of Guangdong Province , Guangzhou , People's Republic of China.

p-Aminosalicylic acid (PAS) is an important second-line antibiotic for treating multidrug-resistant tuberculosis (MDR-TB). Due to gastrointestinal disturbance and intolerance, its potent and efficacy in the treatment of extensively drug-resistant (XDR)-TB commonly are poor. Thus, it is important to reveal the mechanism of susceptibility and resistance of Mycobacterium tuberculosis (Mtb) to this drug. Read More

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https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1
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http://dx.doi.org/10.1080/22221751.2019.1568179DOI Listing
January 2019
2 Reads

Causes of eosinophilic ascites - a systematic review.

Rom J Intern Med 2018 Dec 1. Epub 2018 Dec 1.

Carol Davila School of Medicine, Bucharest, Romania.

Background: In the last years an uprising interest for a relatively unknown entity, eosinophilic ascites (EA), has been recorded. Our aim is to investigate the potential causes of EA development, as well as clinical, laboratory, endoscopic and radiologic features, management and outcome in these patients.

Methods: The following research was performed on PubMed (MEDLINE) database using the medical subject headings [Mesh] terms "Ascites" AND "Eosinophils". Read More

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http://content.sciendo.com/view/journals/rjim/ahead-of-print
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http://dx.doi.org/10.2478/rjim-2018-0041DOI Listing
December 2018
10 Reads

A new hypothesis to investigate bioequivalence of pharmaceutical inhalation products.

Daru 2019 Mar 7. Epub 2019 Mar 7.

Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: This short communication reports a new hypothesis regarding bioequivalence of inhalation products which can potentially provide a reliable means to compare pharmaceutical aerosol formulations and inhalers.

Methods: Available methods regarding the bioequivalence studies, inhaled drugs and advantages of exhaled breath condensate (EBC) samples were reviewed to develop this hypothesis.

Results: It is postulated that two inhalation products providing the same drug concentrations in airway lining fluid (ALF) could be considered bioequivalent. Read More

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http://dx.doi.org/10.1007/s40199-019-00250-xDOI Listing
March 2019
1 Read
1.111 Impact Factor

Multiplex Polymerase Chain Reaction for diagnosis of gastrointestinal tuberculosis.

JGH Open 2019 Feb 17;3(1):32-37. Epub 2018 Oct 17.

Department of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh India.

Background And Aim: To evaluate the role of multiplex polymerase chain reaction (PCR) for diagnosis of gastrointestinal tuberculosis (GITB).

Methods: This was a prospective observational study conducted from July 2015 to November 2016 at a tertiary care teaching institution in north India. Fifty individuals with clinically suspected GITB and older than 18 years of age were recruited. Read More

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http://doi.wiley.com/10.1002/jgh3.12100
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http://dx.doi.org/10.1002/jgh3.12100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6386748PMC
February 2019
4 Reads

Putting in harm to cure: Drug related adverse events do not affect outcome of patients receiving treatment for multidrug-resistant Tuberculosis. Experience from a tertiary hospital in Italy.

PLoS One 2019 28;14(2):e0212948. Epub 2019 Feb 28.

Respiratory Infectious Diseases Unit, National Institute for Infectious Diseases "L. Spallanzani" IRCCS, Rome, Italy.

Rationale: Treatment of multi-drug resistant Tuberculosis (MDR-TB) is challenging because it mostly relies on drugs with lower efficacy and greater toxicity than those used for drug-susceptible TB.

Objectives: Aim of the study was to describe the frequency and type of adverse drug reactions in a cohort of MDR-TB patients and their potential impact on treatment outcome.

Methods: We conducted a retrospective study in a cohort of MDR-TB patients enrolled at a tertiary referral hospital in Italy from January 2008 to December 2016. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212948PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394924PMC
February 2019
2 Reads

Monitoring Treatment of Childhood Tuberculosis and the Role of Therapeutic Drug Monitoring.

Indian J Pediatr 2019 Feb 28. Epub 2019 Feb 28.

Department of Pediatrics, Baylor College of Medicine, 1102 Bates Street, Houston, TX, 77030, USA.

Most children tolerate the first-line antibiotics used to treat Mycobacterium tuberculosis (TB) very well. The most common adverse effect is gastrointestinal distress unrelated to hepatotoxicity; the latter is seen in less than 1% of children. Despite the infrequency of hepatotoxicity, the potential long-term impact of hepatic insufficiency dictates that all children receiving antimycobacterial therapy should be evaluated periodically by symptom screening and physical examination. Read More

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http://dx.doi.org/10.1007/s12098-019-02882-yDOI Listing
February 2019
1 Read

[Gastric tuberculosis].

Rev Prat 2018 Feb;68(2):182

Service de gastro-entérologie.

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February 2018

Safety profile of baricitinib in Japanese patients with active rheumatoid arthritis with over 1.6 years median time in treatment: An integrated analysis of Phases 2 and 3 trials.

Mod Rheumatol 2019 Feb 20:1-8. Epub 2019 Feb 20.

g First Department of Internal Medicine, School of Medicine , University of Occupational and Environmental Health , Kitakyushu , Japan.

Objectives: Baricitinib is a selective oral inhibitor of JAK1/JAK2 for patients with moderately-to-severely active rheumatoid arthritis (RA). Baricitinib's safety profile in Japanese patients was evaluated using six studies (five Ph2/Ph3 trials, one long-term extension study through 01 September 2016) from an integrated database (nine RA studies).

Methods: Incidence rates (IRs) or exposure-adjusted IRs (EAIRs) of adverse events (AEs) per 100 patient-years (PY) were calculated using data which included RA patients exposed to any baricitinib dose. Read More

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http://dx.doi.org/10.1080/14397595.2019.1583711DOI Listing
February 2019
1 Read

A single-shot diagnostic platform based on copper nanoclusters coated with cetyl trimethylammonium bromide for determination of carbamazepine in exhaled breath condensate.

Mikrochim Acta 2019 02 18;186(3):194. Epub 2019 Feb 18.

Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, 51664, Iran.

A fluorescent nanoprobe is designed for the determination of carbamazepine (CBZ) in exhaled breath condensate (EBC) of patients receiving CBZ. The probe consists of copper nanoclusters (Cu NCs) coated with cetyl trimethylammonium bromide. The interaction of probe with CBZ results in blocking non-radiative e/h recombination defect sites on the surface of Cu NCs and consequently enhancing the blue-green fluorescence of Cu NCs (excitation/emission wavelengths: 290/480 nm). Read More

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http://dx.doi.org/10.1007/s00604-019-3278-zDOI Listing
February 2019
2 Reads
3.741 Impact Factor

Frequencies of Common Infectious Organisms Causing Chronic Diarrhea in Renal Transplant Patients.

Exp Clin Transplant 2019 01;17(Suppl 1):212-215

From the Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan.

Objectives: Gastrointestinal complications are common in kidney transplant patients, with the most frequent being diarrhea (60%). Chronic diarrhea affects the patient's quality of life, causes fatigue and weight loss and malabsorption, increases the number of hospitalizations, increases serum creatinine levels, and causes alterations in immunosuppressive drug levels. Diarrhea is also associated with an increased risk of graft failure and death. Read More

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http://dx.doi.org/10.6002/ect.MESOT2018.P69DOI Listing
January 2019
2 Reads
0.798 Impact Factor

The death of Charlotte Brontë from hyperemesis gravidarum and refeeding syndrome: A new perspective.

Clin Nutr 2019 Feb 10. Epub 2019 Feb 10.

Gastrointestinal Surgery, Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH, UK; MRC/ARUK Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UK, UK. Electronic address:

Many theories have been advanced concerning the cause of Charlotte Brontë's death, none of which fully explain all the symptoms she experienced in the course of her final illness. Her death certificate records the cause of death as phthisis (tuberculosis), but there is no evidence, other than circumstantial, to support this diagnosis. A diagnosis of Addison's disease, caused by tuberculosis of the adrenals, has been proposed, but this is unlikely, since it does not fit well with two and a half months of severe anorexia, nausea and vomiting, followed by remission of these symptoms and eventual death. Read More

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http://dx.doi.org/10.1016/j.clnu.2019.01.027DOI Listing
February 2019
1 Read

Avian mycobacteriosis in captive brolgas (Antigone rubicunda).

Aust Vet J 2019 Mar 17;97(3):81-86. Epub 2019 Feb 17.

Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia.

Case Series: Avian mycobacteriosis is a significant disease of a wide range of bird species worldwide. The most common causative agent, Mycobacterium avium, is reported to also infect a range of mammals, including humans. Of 11 brolgas (Antigone rubicunda) submitted to the University of Melbourne for postmortem examination over a 10-year period, 7 were diagnosed with mycobacteriosis. Read More

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http://dx.doi.org/10.1111/avj.12784DOI Listing
March 2019
1 Read

Addison's Disease Caused by Tuberculosis: Diagnostic and Therapeutic Difficulties.

Eur J Case Rep Intern Med 2018 28;5(8):000911. Epub 2018 Aug 28.

Department of Pulmonary Diseases and Tuberculosis, Diakonessenhuis Utrecht, Utrecht, The Netherlands.

Objectives: To demonstrate difficulties in diagnosing and treating Addison's disease caused by tuberculosis.

Materials And Methods: We present a clinical case and review of the literature.

Results: A 62-year-old man presented with gastrointestinal symptoms, weight loss and enlarged adrenal glands. Read More

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http://dx.doi.org/10.12890/2018_000911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346831PMC
August 2018
2 Reads

When the Diagnosis is a Victim of the Circumstances.

Eur J Case Rep Intern Med 2018 26;5(6):000862. Epub 2018 Jun 26.

Internal Medicine, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

Introduction: Haemoptysis is a common symptom which can sometimes mimic gastrointestinal bleeding.

Case Description: We describe the case of a 31-year-old man who presented to the emergency department after an episode of sudden nausea and presumed massive haematemesis. The situation was interpreted as gastrointestinal bleeding but clinical evolution and greater attention to the anamnesis resulted in a diagnosis of pulmonary tuberculosis and the provision of appropriate care. Read More

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http://dx.doi.org/10.12890/2018_000862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346879PMC

Infectious diseases at different stages of migration: an expert review.

J Travel Med 2019 Feb;26(2)

JD MacLean Centre for Tropical Diseases at McGill, McGill University Health Centre, McGill University, Montreal, Canada.

Background: Human migration is increasing in magnitude and scope. The majority of migrants arriving in high-income countries originate from countries with a high prevalence of infectious diseases. The risk and burden of infectious diseases are not equally distributed among migrant groups and vary with migration stage. Read More

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http://dx.doi.org/10.1093/jtm/taz007DOI Listing
February 2019
11 Reads

Esophageal Stricture Caused by in a Patient with No Apparent Predisposing Factors.

Case Rep Gastrointest Med 2019 2;2019:7182976. Epub 2019 Jan 2.

Division of Gastroenterology and Hepatobiliary Diseases, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY, 11215, USA.

species are Gram positive anaerobic or microaerophilic bacteria that are part of the human flora in the oropharyngeal, gastrointestinal, and genitourinary tract. In the presence of a mucosal injury, they can become pathogenic and infect the underlying tissue without respect for tissue planes, leading to abscesses, fistulas, and sinus tracts. Through contiguous and hematogenous spread, virtually any organ can become infected. Read More

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https://www.hindawi.com/journals/crigm/2019/7182976/
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http://dx.doi.org/10.1155/2019/7182976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334373PMC
January 2019
10 Reads

Protective Features of Autophagy in Pulmonary Infection and Inflammatory Diseases.

Cells 2019 Feb 3;8(2). Epub 2019 Feb 3.

Department of Biomedical Sciences, University of North Dakota, Grand Forks, ND 58203, USA.

Autophagy is a highly conserved catabolic process involving autolysosomal degradation of cellular components, including protein aggregates, damaged organelles (such as mitochondria, endoplasmic reticulum, and others), as well as various pathogens. Thus, the autophagy pathway represents a major adaptive response for the maintenance of cellular and tissue homeostasis in response to numerous cellular stressors. A growing body of evidence suggests that autophagy is closely associated with diverse human diseases. Read More

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http://dx.doi.org/10.3390/cells8020123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406971PMC
February 2019
5 Reads

Differentiating Crohn's disease from intestinal tuberculosis.

World J Gastroenterol 2019 Jan;25(4):418-432

Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi 110029, India.

Differentiating Crohn's disease (CD) and intestinal tuberculosis (ITB) has remained a dilemma for most of the clinicians in the developing world, which are endemic for ITB, and where the disease burden of inflammatory bowel disease is on the rise. Although, there are certain clinical (diarrhea/hematochezia/perianal disease common in CD; fever/night sweats common in ITB), endoscopic (longitudinal/aphthous ulcers common in CD; transverse ulcers/patulous ileocaecal valve common in ITB), histologic (caseating/confluent/large granuloma common in ITB; microgranuloma common in CD), microbiologic (positive stain/culture for acid fast-bacillus in ITB), radiologic (long segment involvement/comb sign/skip lesions common in CD; necrotic lymph node/contiguous ileocaecal involvement common in ITB), and serologic differences between CD and ITB, the only exclusive features are caseation necrosis on biopsy, positive smear for acid-fast bacillus (AFB) and/or AFB culture, and necrotic lymph node on cross-sectional imaging in ITB. However, these exclusive features are limited by poor sensitivity, and this has led to the development of multiple multi-parametric predictive models. Read More

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http://dx.doi.org/10.3748/wjg.v25.i4.418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350172PMC
January 2019
9 Reads
2.369 Impact Factor

[A Case of Sigmoid Colon Cancer Identified by Gastric Perforation].

Gan To Kagaku Ryoho 2018 Dec;45(13):2384-2386

Dept. of Surgery, Tokyo Women's Medical University Medical Center East.

We report a case of sigmoid colon cancer that was incidentally found using CT that was performed for upper abdominal pain. An 83-year-old man with a long history of lung tuberculosis and idiopathic pulmonary fibrosis presented with upper abdominal pain. CT findings revealed free gas around the stomach. Read More

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December 2018
5 Reads

Gastric Tuberculosis Presenting as a Subepithelial Mass: A Rare Cause of Gastrointestinal Bleeding.

Korean J Gastroenterol 2018 Dec;72(6):304-307

Department of Surgery, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Gastric tuberculosis accounts for approximately 2% of all cases of gastrointestinal tuberculosis. Diagnosis of gastric tuberculosis is challenging because it can present with various clinical, endoscopic, and radiologic features. Tuberculosis manifesting as a gastric subepithelial tumor is exceedingly rare; only several dozen cases have been reported. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.4166/kjg.2018.72
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http://dx.doi.org/10.4166/kjg.2018.72.6.304DOI Listing
December 2018
8 Reads

Phenotypical and functional evaluation of dendritic cells after exosomal delivery of miRNA-155.

Life Sci 2019 Feb 6;219:152-162. Epub 2019 Jan 6.

Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

Aims: The clinical efficiency of dendritic cell (DC) therapy needs to be improved. Exosomes, as membrane nano-vesicles, carry bio-macromolecules and play essential roles in intercellular crosstalk. Here, it is proposed that tumor cell-derived exosomes could function as vehicles to deliver exogenous miRNA-155 into DCs, for simultaneous miRNA delivery and antigen priming of DCs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00243205193000
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http://dx.doi.org/10.1016/j.lfs.2019.01.005DOI Listing
February 2019
3 Reads
2.702 Impact Factor

Human Hookworm Infection Enhances Mycobacterial Growth Inhibition and Associates With Reduced Risk of Tuberculosis Infection.

Front Immunol 2018 14;9:2893. Epub 2018 Dec 14.

Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, United Kingdom.

Soil-transmitted helminths and frequently coincide geographically and it is hypothesized that gastrointestinal helminth infection may exacerbate tuberculosis (TB) disease by suppression of Th1 and Th17 responses. However, few studies have focused on latent TB infection (LTBI), which predominates globally. We performed a large observational study of healthy adults migrating from Nepal to the UK ( = 645). Read More

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http://dx.doi.org/10.3389/fimmu.2018.02893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302045PMC
December 2018
3 Reads

Case report: systemic tuberculosis caused by Mycobacterium bovis in a cat.

BMC Vet Res 2019 Jan 5;15(1). Epub 2019 Jan 5.

Department of Virology, Faculty of Veterinary Medicine, Ataturk University, Erzurum, Turkey.

Background: The diagnosis of previous cases of feline tuberculosis in Turkey has been made based solely on pathological changes without isolation of the causative agent. This case report details the first case of feline tuberculosis in Turkey for which the causative agent (Mycobacterium bovis) was confirmed with microbiological isolation, morphological evaluation, molecular (PCR) characterization and antibiotic sensitivity.

Case Presentation: Systemic tuberculosis was diagnosed via postmortem examination of a 5-year-old stray male cat. Read More

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http://dx.doi.org/10.1186/s12917-018-1759-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321719PMC
January 2019
6 Reads

Isolated pancreatic tuberculosis with elevated CA 19-9 levels masquerading as a malignancy: A rare case report and literature review.

Medicine (Baltimore) 2018 Dec;97(52):e13858

Department of Hepatobiliary Surgery, Weihai Central Hospital, Weihai, Shandong Province, People's Republic of China.

Rationale: Primary pancreatic tuberculosis is extremely rare, it presents with non-specific clinical symptoms and imaging features; it may be falsely identified as a malignancy of the pancreas.

Patient Concerns: A 41-year-old male with no history of tuberculosis presented to our hospital with a 2-week history of jaundice.

Diagnoses: Abdominal computed tomography (CT) showed a heterogeneous irregular hypodense mass in the head of the pancreas causing dilatation of the common bile duct (CBD), and it was enhanced after infusion of contrast material. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812280-0006
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http://dx.doi.org/10.1097/MD.0000000000013858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314711PMC
December 2018
4 Reads

Impact of Mycobacterium tuberculosis complex lineages as a determinant of disease phenotypes from an immigrant rich moderate tuberculosis burden country.

Respir Res 2018 Dec 27;19(1):259. Epub 2018 Dec 27.

Department of Infection and Immunity, MBC-03, King Faisal Specialist Hospital and Research Centre, Post Box # 3354, Riyadh, 11211, Saudi Arabia.

Background: Growing evidences suggested that the Mycobacterium tuberculosis complex (MTBC) lineages can determine the clinical outcome of pulmonary and extra-pulmonary tuberculosis. However, limited data only available revealing such association of bacterial genotypes and clinical phenotypes from immigrant rich countries.

Methods: A multicenter study has been carried out on a collection of 2092 (1003 extrapulmonary and 1089 pulmonary) MTBC isolates. Read More

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http://dx.doi.org/10.1186/s12931-018-0966-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307224PMC
December 2018

Clinical features and outcomes of abdominal tuberculosis in southeastern Korea: 12 years of experience.

BMC Infect Dis 2018 Dec 27;18(1):699. Epub 2018 Dec 27.

Department of Internal Medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, 15, Jinju-daero 816 beon-gil, Jinju-si, Gyeongnam, 52727, Republic of Korea.

Background: Abdominal tuberculosis (TB) is an uncommon form of infection with Mycobacterium tuberculosis in Korea. In this study, we aimed to highlight the clinical features, diagnostic methods, and outcomes of abdominal TB over 12 years in Southeastern Korea.

Methods: A total of 139 patients diagnosed as having abdominal TB who received anti-TB medication from January 2005 to June 2016 were reviewed. Read More

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http://dx.doi.org/10.1186/s12879-018-3635-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307147PMC
December 2018
6 Reads

Rapid emergence of cryptococcal fungemia, Mycobacterium chelonae vertebral osteomyelitis and gastro intestinal stromal tumor in a young HIV late presenter: a case report.

BMC Infect Dis 2018 Dec 27;18(1):693. Epub 2018 Dec 27.

Division of Infectious Diseases, Department of Clinical and Experimental Medicine, ARNAS Garibaldi Hospital, University of Catania, Catania, Italy.

Background: Highly active antiretroviral therapy has significantly changed the natural history of HIV infection, leading to a dramatic reduction of HIV-related morbidity and mortality. Late Presenters, Very Late Presenters and AIDS presenters still represent, also in Europe, including Italy, a huge challenge in terms of diagnostic and therapeutic management.

Case Presentation: A 35-year-old male with a history of fever and back pain. Read More

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http://dx.doi.org/10.1186/s12879-018-3573-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307234PMC
December 2018
5 Reads

Primary enterolithiasis with intestinal tuberculosis: rare presentation of a common disease.

BMJ Case Rep 2018 Dec 22;11(1). Epub 2018 Dec 22.

Surgery, Lady Hardinge Medical College, New Delhi, India.

Enterolithiasis is the formation of intestinal calculi due to stasis. Tubercular strictures resulting in intestinal stasis provide a favourable environment for enterolith formation. Intestinal tuberculosis occurs commonly in India, but coexistent enterolithiasis has been reported rarely. Read More

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http://dx.doi.org/10.1136/bcr-2018-225469DOI Listing
December 2018

General contextual effects on neglected tropical disease risk in rural Kenya.

PLoS Negl Trop Dis 2018 12 21;12(12):e0007016. Epub 2018 Dec 21.

International Livestock Research Institute, Nairobi, Kenya.

The neglected tropical diseases (NTDs) are characterized by their tendency to cluster within groups of people, typically the poorest and most marginalized. Despite this, measures of clustering, such as within-group correlation or between-group heterogeneity, are rarely reported from community-based studies of NTD risk. We describe a general contextual analysis that uses multi-level models to partition and quantify variation in individual NTD risk at multiple grouping levels in rural Kenya. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007016
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http://dx.doi.org/10.1371/journal.pntd.0007016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342328PMC
December 2018
14 Reads

Anorectal tuberculosis as a chronic rectal mass mimicking rectal prolapse in a child-a case report.

Ann Med Surg (Lond) 2018 Dec 12;36:264-266. Epub 2018 Sep 12.

Division of Infectious Disease, Immunology and International Medicine, University of Illinois College of Medicine at Chicago, Chicago, USA.

Tuberculosis of the colon commonly involves the ascending,transverse, or sigmoid colon while rectal involvement in tuberculosis is uncommon and poorly characterized. We report a six-year-old male from Nepal who presented with abdominal pain and difficulty passing stool for two years. On per rectal examination, palpation revealed a circumferential rectal mass. Read More

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http://dx.doi.org/10.1016/j.amsu.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287574PMC
December 2018
1 Read

Tuberculosis presenting as a pancreatic cystic neoplasm.

BMJ Case Rep 2018 Dec 9;11(1). Epub 2018 Dec 9.

Department of Surgery, Amsterdam UMC, University of Amsterdam, The Netherlands.

A 33-year-old Thai born woman was referred to our tertiary referral hospital with back and epigastric pain. Investigations included abdominal ultrasound and CT scan of the abdomen which demonstrated a 3 cm cystic lesion in the head of the pancreas, most likely a mucinous cystadenoma. Because of its malignant potential resection was advised. Read More

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http://dx.doi.org/10.1136/bcr-2018-225983DOI Listing
December 2018
3 Reads

Evaluation of microsatellite instability in tumor and tumor marginal samples of sporadic colorectal cancer using mononucleotide markers.

EXCLI J 2018 24;17:945-951. Epub 2018 Sep 24.

Department of Medical Genetics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Microsatellite instability (MSI) is a unique molecular alteration that is due to a defective DNA mismatch repair (MMR) system. Approximately, 15-20 % of sporadic colorectal cancers (CRC) display MSI. Determination of MSI status in CRC has prognostic and predictive implications. Read More

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http://dx.doi.org/10.17179/excli2018-1455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295640PMC
September 2018
0.857 Impact Factor

Tuberculous peritonitis diagnosed using laparoscopy with assistance of a central venous catheter.

Exp Ther Med 2018 Dec 12;16(6):5265-5271. Epub 2018 Oct 12.

Department of Gastroenterology, Shenzhen People's Hospital, The Second Affiliated Hospital of Jinan University, Shenzhen, Guangdong 518020, P.R. China.

Laparoscopy with peritoneal biopsy is a tool for rapid and accurate diagnosis of tuberculous peritonitis (TBP). However, laparoscopic procedures are not risk-free; complications include injuries to the gastrointestinal tract and major blood vessels. The purpose of the present study was to introduce a novel method for safe and straightforward laparoscopic diagnosis of TBP. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.6854
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http://dx.doi.org/10.3892/etm.2018.6854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257215PMC
December 2018
12 Reads

An elderly man with gastric cancer, Saint's triad and Heyde's syndrome.

Rev Gastroenterol Peru 2018 Jul-Sep;38(3):289-292

Armed Forces Hospital. Brasília-DF, Brazil.

This case study describes a 71-year-old man with signet-ring cell gastric adenocarcinoma and malignant sigmoidal polyp; and typical features of Saint's triad and Heyde syndrome. He had digestive bleeding, two types of hernia, diverticulosis, arterial hypertension, malignant polyp, and antecedent of smoking, lung tuberculosis, and surgical correction of aortic valve stenosis. There is a hypothetical inverse relationship between herniosis and development of malignancy; however, the patient herein described presented gastric and sigmoidal cancers. Read More

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December 2018
7 Reads

Primary Appendicular Malignancy Presenting as Abdominal Wall Abscess with Secondary Tuberculosis Infection: an Interesting Case Report.

Indian J Surg Oncol 2018 Dec 7;9(4):613-617. Epub 2018 Aug 7.

Parvarish Nursing Home, Andheri, Mumbai, Maharashtra India.

Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Read More

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http://dx.doi.org/10.1007/s13193-018-0804-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265167PMC
December 2018
7 Reads

Esophageal tuberculosis: Uncommon of common.

JGH Open 2018 Apr 2;2(2):34-38. Epub 2018 Apr 2.

Department of Gastroenterology GB Pant Hospital New Delhi India.

Background And Aim: Esophageal involvement in tuberculosis (TB) is rare and is usually secondary. Data on esophageal TB are scarce. We aimed to analyze clinical and endoscopic features and outcomes of treatment in esophageal TB. Read More

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http://doi.wiley.com/10.1002/jgh3.12043
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http://dx.doi.org/10.1002/jgh3.12043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207044PMC
April 2018
13 Reads

Does long sleep duration increase risk of metabolic syndrome in Azar cohort study population?

Health Promot Perspect 2018 27;8(4):290-295. Epub 2018 Oct 27.

Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

We decided to assess the correlation between metabolic syndrome (MetS) risks,sleep and napping duration in Azar cohort population according to the increasing incidence of MetS in the world and inconsistence results about sleep duration and MetS. In this cross-sectional study, MetS and sleep habits of 14916 subjects (35-70 years old) who inhabited in Shabestar city were determined by ATPIII and Pittsburg questionnaire respectively. Inclusion criteria were subjects with 35-70 years old and living in Shabestar for at least 9 months of the year. Read More

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http://dx.doi.org/10.15171/hpp.2018.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249496PMC
October 2018
12 Reads

Heterologous Boost Following Reduces the Late Persistent, Rather Than the Early Stage of Intranasal Tuberculosis Challenge Infection.

Front Immunol 2018 30;9:2439. Epub 2018 Oct 30.

Department of Pathogen Biology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Adults are the leading population affected by tuberculosis (TB) epidemic and death. Developing an effective vaccine against adult TB is urgently needed. Bacillus Calmette-Guerin (BCG) prime-heterologous boost strategy has been explored extensively to protect adults against primary TB infection, but the majority of experimental regimens have not improved the protection primed by the BCG vaccine. Read More

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02439
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http://dx.doi.org/10.3389/fimmu.2018.02439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218689PMC
October 2018
24 Reads

[Gastric tuberculosis in an elderly patient:a case report].

Nihon Shokakibyo Gakkai Zasshi 2018;115(11):985-995

Department of Gastroenterology, Toyohashi Municipal Hospital.

A woman in her 70s presented to our hospital with epigastric pain, back pain, and weight loss. Esophagogastroduodenoscopy was performed, and numerous protuberances, which were suspected to be submucosal tumors, were found at the gastric corpus. The patient was diagnosed with gastric tuberculosis based on the biopsy results of these protuberances. Read More

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https://www.jstage.jst.go.jp/article/nisshoshi/115/11/115_98
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http://dx.doi.org/10.11405/nisshoshi.115.985DOI Listing
January 2018
10 Reads

Hepatitis C virus, directly acting antivirals and Guillain-Barré syndrome.

Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1237-1239

Department of Nephrology, Jawaharlal Nehru Medical College, Wardha, Maharashtra, India.

Guillain-Barré syndrome (GBS) has been associated with both infective and noninfective etiologies. It is usually preceded by acute gastrointestinal or respiratory infections. We report an unusual case of GBS in a hepatitis C virus-positive hemodialysis (HD)-dependent patient who was being treated with sofosbuvir and daclatasvir along with antitubercular drugs for pulmonary tuberculosis. Read More

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http://www.sjkdt.org/text.asp?2018/29/5/1237/243969
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http://dx.doi.org/10.4103/1319-2442.243969DOI Listing
November 2018
6 Reads

Acquired zinc deficiency in a renal transplant recipient with gastrointestinal tuberculosis responding promptly to oral correction.

Saudi J Kidney Dis Transpl 2018 Sep-Oct;29(5):1199-1202

Department of Dermatology, Jaslok Hospital and Research Center, Mumbai, Maharashtra, India.

Zinc deficiency is an uncommon condition, known to occur in two forms: inherited type, known as Acrodermatitis enteropathies and the acquired type. Cutaneous clinical manifestations observed include characteristic dermatitis on acral, periorificial, and anogenital areas through an unknown mechanism. The patient had a combination of causes which lead to a state of zinc deficiency. Read More

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http://www.sjkdt.org/text.asp?2018/29/5/1199/243962
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http://dx.doi.org/10.4103/1319-2442.243962DOI Listing
November 2018
21 Reads

Epidemiology and Outcomes of Nontyphoidal Bacteremias from England, 2004 to 2015.

J Clin Microbiol 2019 Jan 2;57(1). Epub 2019 Jan 2.

Tuberculosis, Acute Respiratory, Gastrointestinal, Emerging/Zoonotic Infections, and Travel and Migrant Health Division, National Infection Service, Public Health England, London, United Kingdom

Nontyphoidal (NTS) bacteremia causes hospitalization and high morbidity and mortality. We linked Gastrointestinal Bacteria Reference Unit (GBRU) data to the Hospital Episode Statistics (HES) data set to study the trends and outcomes of NTS bacteremias in England between 2004 and 2015. All confirmed NTS isolates from blood from England submitted to GBRU between 1 January 2004 and 31 December 2015 were deterministically linked to HES records. Read More

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http://dx.doi.org/10.1128/JCM.01189-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322475PMC
January 2019
7 Reads

Efficacy of acupressure to prevent adverse reactions to anti-tuberculosis drugs: Randomized controlled trials.

J Adv Nurs 2019 Mar 11;75(3):640-651. Epub 2019 Feb 11.

Institute of Clinical Nursing, National Yang-Ming University, Taipei, Taiwan.

Aim: To determine whether acupressure can prevent or relieve the adverse drug reactions (ADRs) of anti-tuberculosis drugs.

Background: People receiving drug treatment for TB often experience ADRs that may cause them to stop taking their medication. Acupressure is a form of traditional Chinese medicine that can be applied to alleviate or prevent disease symptoms. Read More

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http://doi.wiley.com/10.1111/jan.13881
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http://dx.doi.org/10.1111/jan.13881DOI Listing
March 2019
11 Reads