8,351 results match your criteria Trigeminal Neuralgia


Executive Dysfunction After Fourth-Ventricle Epidermoid Cyst Resection.

Cogn Behav Neurol 2018 Dec;31(4):207-213

Neuropsychology Research Unit, The University of Queensland, Brisbane, Australia.

Intracranial epidermoid cysts are rare, comprising 0.2% to 1.8% of all primary intracranial expanding lesions, of which <5% occur within the fourth ventricle. Read More

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http://dx.doi.org/10.1097/WNN.0000000000000175DOI Listing
December 2018

Radiosurgery for multiple sclerosis-related trigeminal neuralgia: retrospective review of long-term outcomes.

Authors:

J Neurosurg 2018 Nov 1:1-8. Epub 2018 Nov 1.

OBJECTIVEThe objective of this study was to assess long-term outcomes of facial pain and numbness after radiosurgery for multiple sclerosis (MS)-related trigeminal neuralgia (MS-TN).METHODSThe authors conducted a retrospective review of their Gamma Knife radiosurgeries (GKRSs) to identify all patients treated for MS-TN (1998-2014) with at least 3 years of follow-up. Treatment and clinical data were obtained via chart review and mailed or telephone surveys. Read More

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http://dx.doi.org/10.3171/2018.5.JNS173194DOI Listing
November 2018

Endoscopic versus open microvascular decompression for trigeminal neuralgia: a systematic review and comparative meta-analysis.

Authors:

J Neurosurg 2018 Dec 1:1-9. Epub 2018 Dec 1.

OBJECTIVEMicrovascular decompression (MVD) is commonly used in the treatment of trigeminal neuralgia (TN) with positive clinical outcomes. Fully endoscopic MVD (E-MVD) has been proposed as an effective minimally invasive alternative, but a comparative review of the two approaches has not been conducted. The authors performed a meta-analysis of studies, comparing patient outcome rates and complications for the open versus the endoscopic technique. Read More

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http://dx.doi.org/10.3171/2018.6.JNS172690DOI Listing
December 2018

Medial Gamma Knife thalamotomy for intractable pain.

Authors:

J Neurosurg 2018 Dec;129(Suppl1):72-76

OBJECTIVEAblative procedures are still useful in the treatment of intractable pain despite the proliferation of neuromodulation techniques. In the paper the authors present the results of Gamma Knife thalamotomy (GKT) in various pain syndromes.METHODSBetween 1996 and 2016, unilateral GKT was performed in 30 patients suffering from various severe pain syndromes in whom conservative treatment had failed. Read More

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http://dx.doi.org/10.3171/2018.7.GKS181583DOI Listing
December 2018

Orofacial neuralgia associated with a middle cerebral artery aneurysm.

Aust Dent J 2018 Dec 7. Epub 2018 Dec 7.

Senior Lecturer, School of Dentistry, University of Adelaide, South Australia, Australia.

Chronic orofacial pain of neuropathic origin can present diagnostic and management dilemmas to dental practitioners and also affect the patient's quality of life. Intracranial aneurysms are a potential cause of stroke, with associated sub-arachnoid haemorrhage leading to high rates of mortality and morbidity. A patient who had been previously managed for symptoms of temporomandibular joint disorder (TMD) presented with sharp, shooting pain of moderate intensity. Read More

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http://dx.doi.org/10.1111/adj.12668DOI Listing
December 2018
1 Read

The role of the otolaryngologist in the evaluation and management of headaches.

Am J Otolaryngol 2019 Jan - Feb;40(1):115-120. Epub 2018 Jul 7.

Department of Otolaryngology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, United States.

Background: Headaches are commonly evaluated in otolaryngology and often represent a diagnostic dilemma. This review addresses rhinogenic headache as well as trigeminal neuralgia and migraine, both of which can masquerade as sinus headache and whose management increasingly involves otolaryngology intervention. Discussion considers diagnostic criteria and novel therapies and derives an algorithm for clinical decision-making. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.07.002DOI Listing

Altered spontaneous brain activity in classical trigeminal neuralgia as determined by changes in regional homogeneity: a resting-state functional MRI study.

Pain Pract 2018 Dec 11. Epub 2018 Dec 11.

Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Province Ocular Disease Clinical Research Center Nanchang 330006 Jiangxi, People's Republic of China.

Objective: Neuroimaging studies have reported that patients with pain-related conditions have altered neuronal activity and structural functions. The purpose of this study was to investigate whether classical trigeminal neuralgia (CTN) patients exhibit changes in corresponding neuronal activity via analysis of neuronal activity regional homogeneity (ReHo).

Methods: A total of 28 patients presenting with sore eyes (12 men and 16 women) were matched with 28 healthy controls (12 men and 16 women). Read More

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http://dx.doi.org/10.1111/papr.12753DOI Listing
December 2018

Unconventional Facial Entry Points Confirmed Using a 3D CT Reconstruction-Guided Stereotactic Approach to Radiofrequency Thermocoagulation for the Treatment of Trigeminal Neuralgia: A Series of Case Reports.

Pain Med 2018 Dec 7. Epub 2018 Dec 7.

Department of Neurosurgery.

Objectives: Patients with trigeminal neuralgia who are refractory to medical therapy may choose to undergo Gasserian ganglion percutaneous radiofrequency thermocoagulation. However, in cases where the foramen ovale is difficult to access due to various anatomical anomalies, the typical estimation of the facial entry point is suboptimal.

Methods: Three-dimensional computed tomography reconstruction imaging performed before surgery revealed anatomical variations in each of the four adult patient cases that made it more difficult to successfully access the foramen ovale (FO) for percutaneous radiofrequency thermocoagulation. Read More

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http://dx.doi.org/10.1093/pm/pny262DOI Listing
December 2018

CRC9: Management of Trigeminal Neuralgia in a Patient after Lower Tooth Extraction: A Case Report.

J Indian Prosthodont Soc 2018 Oct;18(Suppl 1):S39

Department of Prosthodontics, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.

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http://dx.doi.org/10.4103/0972-4052.244664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238492PMC
October 2018

Diffuse Large B Cell Lymphoma presented as trigeminal neuralgia: two cases reported and literatures review.

World Neurosurg 2018 Dec 5. Epub 2018 Dec 5.

Department of Neurosurgery, Xinhua hospital affiliated to Shanghai Jiaotong University School of Medicine. Electronic address:

Objective: Extra-axial lymphoma involving the trigeminal nerve, an uncommon condition that presents as a trigeminal schwannoma, resulted in misdiagnosis and a flawed surgical strategy. We report two cases: a primary lymphoma of Meckel's cave and a metastasis lymphoma in the prepontine cistern arising from the supraclavicular lymph node.

Cases Report: The first patient presented with a 3-month history of persistent, sharp facial pain across the area innervated by the V2 nerve. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.217DOI Listing
December 2018

AAPT Diagnostic Criteria for Peripheral Neuropathic Pain: Focal and Segmental Disorders.

J Pain 2018 Dec 4. Epub 2018 Dec 4.

Department of Anesthesiology and Washington University Pain Center, Washington University School of Medicine, St Louis, MO.

Peripheral neuropathic pain is among the most prevalent types of neuropathic pain. No comprehensive peripheral neuropathic pain classification system that incorporates contemporary clinical, diagnostic, biological, and psychological information exists. To address this need, this article covers the taxonomy for 4 focal or segmental peripheral neuropathic pain disorders, as part of the Analgesic, Anesthetic, and Addiction Clinical Trial Translations, Innovations, Opportunities, and Networks (ACTTION) public-private partnership and the American Pain Society (APS) collaborative to develop a standardized, evidence-based taxonomy initiative: the ACTTION-APS Pain Taxonomy (AAPT). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15265900183072
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http://dx.doi.org/10.1016/j.jpain.2018.10.002DOI Listing
December 2018
2 Reads

Evaluation of biochemical variables in patients with trigeminal neuralgia.

Br J Oral Maxillofac Surg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurology, Faculty of Medicine, Adıyaman University, 02000, Adiyaman, Turkey. Electronic address:

The aim of this study was to evaluate the calcium, sodium, potassium, serum iron, vitamin B12, and albumin concentrations, and alkaline phosphatase (ALP) activity, in samples of serum from patients with primary trigeminal neuralgia (TN), and investigate the associations between them. Results from 73 patients who had been diagnosed with primary TN between December 2015 and 2017 were compared with those of 70 healthy subjects. Calcium (p=0. Read More

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http://dx.doi.org/10.1016/j.bjoms.2018.11.012DOI Listing
December 2018

Study on the Therapeutic Effects of Trigeminal Neuralgia With Microvascular Decompression and Stereotactic Gamma Knife Surgery in the Elderly.

J Craniofac Surg 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurosurgery, The Second Hospital of Shandong University, Jinan, China.

Objective: The aim of the study was to evaluate the efficacy of microvascular decompression (MVD) and stereotactic gamma knife surgery (GKS) in the treatment of trigeminal neuralgia (TN) in the elderly.

Patients And Methods: Retrospective analysis of 137 elderly cases with TN underwent MVD, partial sensory rhizotomy (PR) treatment from August 2007 to March 2017 and 56 cases underwent GKS treatment from May 2014 to February 2017 was made, compared the efficacy of MVD and GKS in different age groups.

Results: In 125 patients of MVD alone, the responsible vessels included 60 cases of superior cerebellar artery, 55 cases of anterior inferior cerebellar artery, 4 cases of venous vascular compression, 13 cases of mixed arteriovenous compression and 3 cases of vertebral artery, and 2 cases of no responsible vessel. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004999DOI Listing
November 2018
2 Reads

Ring graft technique for microvascular decompression.

Neurol India 2018 Nov-Dec;66(6):1687-1691

Department of Neurosurgery, GIPMER and Maulana Azad Medical College, New Delhi, India.

Introduction: Various nerve compression syndromes, such as trigeminal neuralgia (TN), glossopharyngeal neuralgia (GN), and hemifacial spasm (HFS), are caused by compression of the concerned nerve by the adjacent vessel. Patients who do not respond to medical management are usually treated by "microvascular decompression (MVD) of the nerve." Teflon patch graft is the most commonly used material for MVD. Read More

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http://dx.doi.org/10.4103/0028-3886.246282DOI Listing
December 2018
2 Reads
1.084 Impact Factor

Efficacy and safety of CT-guided percutaneous pulsed radiofrequency treatment of the Gasserian ganglion in patients with medically intractable idiopathic trigeminal neuralgia.

J Pain Res 2018 19;11:2877-2885. Epub 2018 Nov 19.

Department of Anesthesiology and Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, PR China,

Background: There is a lack of prospective studies for the long-term results of percutaneous pulsed radiofrequency (PRF) of the Gasserian ganglion in the treatment of patients with medically refractory trigeminal neuralgia (TN).

Methods And Results: We prospectively observed the outcomes of 28 idiopathic TN patients (between July 2013 and July 2016) who received CT-guided percutaneous PRF treatment of the Gasserian ganglion. All of the patients had stopped responding to drug therapy before PRF treatment. Read More

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http://dx.doi.org/10.2147/JPR.S179228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250108PMC
November 2018
1 Read

Trigeminal Neuralgia Caused by Dural Arteriovenous Fistula in Meckel Cave Treated with Gamma Knife Radiosurgery: A Case Report.

World Neurosurg 2018 Nov 27. Epub 2018 Nov 27.

Department of Radiology, Mayo Clinic, 4500 San Pablo Road S, Jacksonville, Florida, USA, 32224; Department of Neurologic Surgery, Mayo Clinic, Jacksonville, FL, USA, 4500 San Pablo Road S, Jacksonville, Florida, USA. Electronic address:

Background: Classic trigeminal neuralgia is an often debilitating condition that frequently results from vascular compression at the root entry zone of the trigeminal nerve. Here, the authors report a case of dural arteriovenous fistula surrounding the trigeminal nerve from near the root entry zone extending as far ventral as Meckel cave treated solely with Gamma Knife radiosurgery.

Case Description: A 71-year-old woman presented with a history of persistent attacks of right facial pain after failed conservative management. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183273
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http://dx.doi.org/10.1016/j.wneu.2018.11.177DOI Listing
November 2018
7 Reads

Immunohistochemical analysis of histone H3 acetylation in the trigeminal root entry zone in an animal model of trigeminal neuralgia.

Authors:

J Neurosurg 2018 Nov 1:1-11. Epub 2018 Nov 1.

OBJECTIVEThe trigeminal root entry zone (TREZ) is a transitional zone between the central nervous system (CNS) and peripheral nervous system (PNS), adjacent to the brainstem. Microvascular compression of the TREZ has been considered to be the primary etiology in most cases of trigeminal neuralgia (TN), but whether epigenetic regulation is involved in the pathogenesis of TN is still unclear. Therefore, this study was designed to investigate the epigenetic regulation of histone H3 acetylation in the TREZ in an animal model of TN. Read More

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http://dx.doi.org/10.3171/2018.5.JNS172948DOI Listing
November 2018
1 Read

Surgical management of coexisting trigeminal neuralgia and hemifacial spasm.

Surg Neurol Int 2018 23;9:214. Epub 2018 Oct 23.

Department of Neurosurgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Coexisting hemifacial spasm (HFS) and trigeminal neuralgia (TN) without any mass lesion in the posterior fossa is a rare condition. Hence, the surgical strategy of coexisting HFS and TN has rarely been discussed.

Case Description: We present a rare case of coexisting HFS and TN without any mass lesion in posterior fossa having microvascular confliction of trigeminal nerve with superior cerebellar artery (SCA) and facial nerve with anterior inferior cerebellar artery (AICA). Read More

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http://dx.doi.org/10.4103/sni.sni_188_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213807PMC
October 2018

Repeat Gamma Knife radiosurgery versus microvascular decompression following failure of GKRS in trigeminal neuralgia: a systematic review and meta-analysis.

Authors:

J Neurosurg 2018 Oct 1:1-10. Epub 2018 Oct 1.

OBJECTIVEGamma Knife radiosurgery (GKRS) has emerged as a promising treatment modality for patients with classical trigeminal neuralgia (TN); however, considering that almost half of the patients experience post-GKRS failure or lesion recurrence, a repeat treatment is typically necessary. The existing literature does not offer clear evidence to establish which treatment modality, repeat GKRS or microvascular decompression (MVD), is superior. The present study aimed to compare the overall outcome of patients who have undergone either repeat GKRS or MVD after failure of their primary GKRS; the authors do so by conducting a systematic review and meta-analysis of the literature and analysis of data from their own institution. Read More

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http://dx.doi.org/10.3171/2018.5.JNS18583DOI Listing
October 2018

Long-term pain outcomes for recurrent idiopathic trigeminal neuralgia after stereotactic radiosurgery: a prospective comparison of first-time microvascular decompression and repeat stereotactic radiosurgery.

Authors:

J Neurosurg 2018 Oct 1:1-9. Epub 2018 Oct 1.

OBJECTIVEMicrovascular decompression (MVD) and stereotactic radiosurgery (SRS) are common surgical treatments for trigeminal neuralgia (TN). Many patients who receive SRS have pain recurrence; the ideal second intervention is unknown. The authors directly compared pain outcomes after MVD and repeat SRS in a population of patients in whom SRS failed as their first-line procedure for TN, and they identified predictors of pain control. Read More

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http://dx.doi.org/10.3171/2018.5.JNS172243DOI Listing
October 2018

[Neuronavigation-assisted percutaneous radiofrequency thermocoagulation of trigeminal gasserian ganglion for refractory craniofacial pain].

Zhonghua Yi Xue Za Zhi 2018 Nov;98(43):3519-3523

Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Neurological Center of Fujian Province, Fuzhou 350000, China.

Percutaneous radiofrequency thermocoagulation (RFT) of the Gasserian ganglion is an effective treatment for refractory trigeminal craniofacial pain.In the present study, we assessed the feasibility of accessing the Gasserian ganglion through the foramen ovale with neuronavigation guidance in the patients of trigeminal craniofacial pain. We retrospectively analyzed forty-four patients with type Ⅰ trigeminal neuralgia who had undergone percutaneous RFT treatment in our hospital from June 2014 to December 2016. Read More

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November 2018
4 Reads

Microsurgical Decompression of Trigeminal Neuralgia Caused by Simultaneous Double Arterial (SCA and AICA) and Petrosal Vein Complex Compression.

J Neurol Surg B Skull Base 2018 Dec 25;79(Suppl 5):S428-S430. Epub 2018 Sep 25.

Semmes Murphey Neurologic and Spine Institute, Memphis, Tennessee, United States.

Trigeminal neuralgia is a chronic pain disorder affecting the face. In approximately 80% of cases, it is most commonly caused, when the root entry zone (REZ) of the trigeminal nerve is compressed by the superior cerebellar artery (SCA). The etiology of the remaining 20% of cases is distributed among venous, arteriovenous malformations, posterior fossa tumors, multiple sclerosis plaque compressions, and other pathologies. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669968
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http://dx.doi.org/10.1055/s-0038-1669968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243231PMC
December 2018
6 Reads

Risk of radiation-associated intracranial malignancy after stereotactic radiosurgery: a retrospective, multicentre, cohort study.

Lancet Oncol 2018 Nov 22. Epub 2018 Nov 22.

Department of Neurosurgery, Laura and Isaac Perlmutter Cancer Center, NYU Langone Health System, New York University, New York, NY, USA. Electronic address:

Background: A major concern of patients who have stereotactic radiosurgery is the long-term risk of having a secondary intracranial malignancy or, in the case of patients with benign tumours treated with the technique, the risk of malignant transformation. The incidence of stereotactic radiosurgery-associated intracranial malignancy remains unknown; therefore, our aim was to estimate it in a population-based study to assess the long-term safety of this technique.

Methods: We did a population-based, multicentre, cohort study at five international radiosurgery centres (Na Homolce Hospital, Prague, Czech Republic [n=2655 patients]; Ruber International Hospital, Madrid, Spain [n=1080], University of Pittsburgh Medical Center, Pittsburgh, PA, USA [n=1027]; University of Virginia, Charlottesville, VA, USA [n=80]; and NYU Langone Health System, New York, NY, USA [n=63]). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183065
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http://dx.doi.org/10.1016/S1470-2045(18)30659-4DOI Listing
November 2018
9 Reads

A pain to the patient and to the doctor.

Pract Neurol 2018 Nov 21. Epub 2018 Nov 21.

Department of Neurology, Centro Hospitalar de Lisboa Central, Lisbon, Portugal.

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http://dx.doi.org/10.1136/practneurol-2018-002072DOI Listing
November 2018

Combined Presigmoid and Retrosigmoid Approach to Petroclival Meningiomas.

J Neurol Surg B Skull Base 2018 Dec 25;79(Suppl 5):S402-S403. Epub 2018 Sep 25.

Department of Neurosurgery, Evangelic University Hospital of Curitiba, Parana, Brazil.

 The management of petroclival meningiomas is among the most intimidating in neurosurgery, due to its difficult accessibility and close relationship with vital structures; therefore, an appropriate exposure is mandatory. We present a surgical video demonstrating a presigmoid transtentorial approach, associated with the opening of the retrosigmoid dura to a petroclival meningioma, performed by the senior surgeon (L.A. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669965
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http://dx.doi.org/10.1055/s-0038-1669965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240352PMC
December 2018
5 Reads

Resection of a Petroclival Meningioma via the Endoscope-Assisted Retrosigmoid Approach: 2-D Operative Video.

J Neurol Surg B Skull Base 2018 Dec 1;79(Suppl 5):S395-S396. Epub 2018 Oct 1.

Department of Neurological Surgery, Eberhard-Karls University, University Hospital Tübingen, Tübingen, Germany.

We present a case of a petroclival meningioma that was resected through an endoscope-assisted retrosigmoid approach via corridors above and below the facial-vestibulocochlear nerve complex. The patient is a 61-year-old female with complaints of left-sided hypesthesia and neuralgia of the infraorbital and zygomatic region, intermittent periorbital myokymia, and a slight facial palsy (HB II). This 2D video demonstrates the operative technique, anatomical and surgical nuances of the skull base approach and microdissection of the tumor from the critical neurovascular structures. Read More

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http://dx.doi.org/10.1055/s-0038-1669984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240343PMC
December 2018
1 Read

Surgical treatment of trigeminal neuralgia with no neurovascular compression: A retrospective study and literature review.

J Clin Neurosci 2018 Dec 24;58:42-48. Epub 2018 Oct 24.

Department of Skull Base Surgery Center, Department of Neurosurgery, XuanWu Hospital, Capital Medical University, Beijing, China.

The objective of the current study is to summarize the experiences of 360-degree circumferential arachnoid dissection for TN in patients without NVC. Clinical data from 19 TN patients without NVC who underwent 360-degree circumferential arachnoid dissection were retrospectively analyzed. All patients underwent preoperative examinations of three-dimensional time-of-flight magnetic resonance angiography (3D-TOF-MRA) and three-dimensional nuclear magnetic resonance of constructive interference in steady state (3D-CISS) to identify the neurovascular structures around the trigeminal nerve. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183044
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http://dx.doi.org/10.1016/j.jocn.2018.10.066DOI Listing
December 2018
3 Reads

Long-term pain relief at five years after medical, repeat surgical procedures or no management for recurrence of trigeminal neuralgia after microvascular decompression: analysis of a historical cohort.

Br J Neurosurg 2018 Nov 19:1-6. Epub 2018 Nov 19.

b Oral Medicine Unit, Eastman Dental Institute , UCLH NHS Foundation Trust , London , UK.

Background: Management strategies for the recurrence of trigeminal neuralgia after microvascular decompression include repeat procedures, medical management or no further therapy. No consensus exists as to which strategy is best for pain relief. The aim of this study was to determine the characteristics of patients with recurrences after microvascular decompression in the cohort, and to compare long-term pain relief between different management strategies. Read More

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http://dx.doi.org/10.1080/02688697.2018.1538484DOI Listing
November 2018

The Use of a Sub-Temporal Approach for a Salvage Placement of a Trigeminal Ganglion Stimulating Electrode for the Treatment of Trigeminal Neuropathic Pain.

World Neurosurg 2018 Nov 14. Epub 2018 Nov 14.

Emory University School of Medicine, Department of Neurosurgery; Georgia Institute of Technology, Department of Biomedical Engineering.

Background And Importance: Trigeminal ganglion stimulation can be effective for trigeminal neuralgia. For patients who respond well to neurostimulation delivered percutaneously through the foramen ovale but require extensive revision and removal of instrumentation, a sub-temporal approach for stimulation of the trigeminal ganglion is an alternative option as a salvage procedure.

Clinical Presentation: Here we report a 47-year old woman who responded well to neurostimulation for trigeminal neuropathic pain over a one-year period from 2008-2009. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.034DOI Listing
November 2018
4 Reads

Pain threshold monitoring during chronic constriction injury of the infraorbital nerve in rats.

Br J Neurosurg 2018 Nov 15:1-4. Epub 2018 Nov 15.

a Department of Neurosurgery, XinHua Hospital (The Cranial Nerve Disease Center of Shanghai) , Shanghai JiaoTong University School of Medicine , Shanghai , China.

Background: The chronic constriction injury (CCI) of the infraorbital nerve (ION) has been used to establish an animal mode of trigeminal neuralgia (TN), but key parameters of the model have not been quantified until now.

Objective: The aim of the study was to quantify a standard of pain threshold to evaluate a successful TN model in Sprague-Dawley (SD) rats.

Methods: Forty-eight adult SD rats (200-220 g) underwent chronic constriction injury of the infraorbital nerve. Read More

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http://dx.doi.org/10.1080/02688697.2018.1538483DOI Listing
November 2018
4 Reads

First Bite Syndrome After Trigeminal Radiosurgery: Case Report and Pathophysiology.

Headache 2018 Nov 15;58(10):1680-1681. Epub 2018 Nov 15.

Department of Evaluation and Treatment of Pain, Clinical Neuroscience Federation, La Timone Hospital, FHU INOVPAIN, Aix-Marseille University, INSERM U-1107, CHU de Clermont-Ferrand, Marseille, France.

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http://doi.wiley.com/10.1111/head.13449
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http://dx.doi.org/10.1111/head.13449DOI Listing
November 2018
2 Reads

Analysis of morphological measurements of the trigeminal nerve in the linac stereotactic radiosurgery simulation targeting the root entry zone in trigeminal neuralgia.

Neurocirugia (Astur) 2018 Nov 10. Epub 2018 Nov 10.

Department of Neurosurgery, National Institute of Neurology and Neurosurgery "Manuel Velasco Suarez", Mexico City, Mexico; Department of Radioneurosurgery, ABC Medical Center, Mexico City, Mexico. Electronic address:

Purpose: To describe the anatomical measurements of the trigeminal nerve in patients with trigeminal neuralgia (TN) during Linac (linear accelerator)-based stereotactic radiosurgery (SRS) simulation, targeting the root entry zone (REZ), with a 30% isodose line tangential to the pons, using 4-mm and 6-mm collimators.

Methods: In this retrospective study, 53 TN patients, who underwent Fiesta sequence scanning prior to any treatment modality, were assessed. Bilateral measurements were obtained from the cisternal segment of the trigeminal nerve, the trigeminal-pontine angle, and the lateral width of the pontine cistern on the Fiesta MRI sequence. Read More

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http://dx.doi.org/10.1016/j.neucir.2018.10.001DOI Listing
November 2018

An epidermoid cyst of the cerebellopontine angle presenting with the contralateral trigeminal neuralgia : An extremely rare case and the review of literature.

World Neurosurg 2018 Nov 7. Epub 2018 Nov 7.

Department of General Surgery, Sri Aurobindo Medical College and P.G. Institute, Indore, India.

An epidermoid cyst is a rare tumor of the cerebellopontine angle region. It usually presents with ipsilateral compressive symptoms. The contralateral trigeminal neuralgia is an unusual presentation in such cases. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.204DOI Listing
November 2018

The association between auditory nerve neurovascular conflict and sudden unilateral sensorineural hearing loss.

Laryngoscope Investig Otolaryngol 2018 Oct 6;3(5):384-387. Epub 2018 Oct 6.

Departments of Otolaryngology Head Neck and Maxillofacial Surgery.

Hypothesis: There may be an association between a neurovascular conflict (NVC) of the auditory nerve and unilateral sudden sensorineural hearing loss (SSNHL).

Background: Compression of cranial nerves by vascular structures can lead to significant symptomatology that may require surgical decompression. Notable examples are trigeminal neuralgia and hemifacial spasm. Read More

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http://doi.wiley.com/10.1002/lio2.209
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http://dx.doi.org/10.1002/lio2.209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209614PMC
October 2018
8 Reads

Outcome of Internal Neurolysis for Trigeminal Neuralgia without Neurovascular Compression and Its Relationship with Intraoperative Trigeminocardiac Reflex.

Stereotact Funct Neurosurg 2018 7;96(5):305-310. Epub 2018 Nov 7.

School of Medicine, Shandong University, Jinan,

Background: Internal neurolysis (IN) is an effective surgical treatment for trigeminal neuralgia (TN) without neurovascular compression (NVC) or postoperative recurrence. However, the trigeminal nerve is directly manipulated during the procedure, and there is a high incidence of trigeminocardiac reflex (TCR). The aim of this study was to retrospectively analyze the outcome of IN and to explore its relationship with the occurrence of intraoperative TCR. Read More

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https://www.karger.com/Article/FullText/493547
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http://dx.doi.org/10.1159/000493547DOI Listing
November 2018
7 Reads

Radiofrequency thermocoagulation combined with pulsed radiofrequency for gasserian ganglion blockage.

Agri 2018 Oct;30(4):179-182

Department of Anaesthesiology, Reanimation and Pain, Dr. Ersin Arslan Research and Training Hospital, Gaziantep, Turkey.

Objectives: Trigeminal neuralgia (TN) has been effectively treated by radiofrequency thermocoagulation (RFT) of the gasserian ganglion. Recently, pulsed radiofrequency (PRF) is becoming an alternative therapy for patients with trigeminal neuralgia. It is unclear whether the combination of RFT with PRF may decrease post-operative complications while maintaining longterm pain relief. Read More

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October 2018
3 Reads

Accuracy of the painDETECT screening questionnaire for detection of neuropathic components in hospital-based patients with orofacial pain: a prospective cohort study.

J Headache Pain 2018 Nov 6;19(1):103. Epub 2018 Nov 6.

Eastman Dental Institute, UCLH NHS Foundation Trust, London, UK.

Background: Better tools are required for the earlier identification and management of orofacial pain with different aetiologies. The painDETECT questionnaire is a patient-completed screening tool with utility for identification of neuropathic pain in a range of contexts. 254 patients, referred from primary care for management of orofacial pain and attending a secondary care centre, were prospectively recruited, and completed the painDETECT prior to consultation. Read More

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http://dx.doi.org/10.1186/s10194-018-0932-5DOI Listing
November 2018
6 Reads

Familial Trigeminal Neuralgia Cases Implicate Genetic Factors in Disease Pathogenesis.

JAMA Neurol 2018 Nov 5. Epub 2018 Nov 5.

Department of Neurosurgery, Yale School of Medicine, New Haven, Connecticut.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2018.3322DOI Listing
November 2018
4 Reads

Eslicarbazepine acetate reduces trigeminal nociception: Possible role of adrenergic, cholinergic and opioid receptors.

Life Sci 2018 Dec 27;214:167-175. Epub 2018 Oct 27.

Department of Pharmacology, Faculty of Pharmacy, University of Belgrade, Vojvode Stepe 450, P.O. Box 146, 11221 Belgrade, Serbia.

Aims: Eslicarbazepine acetate (ESL) is a novel dibenzazepine antiepileptic, that has demonstrated efficacy against trigeminal pain, both in preclinical and clinical studies. However, ESL's mechanism of antinociceptive action remains uncertain. Here, we aimed to examine the contribution of adrenergic/cholinergic/opioid receptors to the antinociceptive effects of ESL in a trigeminal pain model, as these neurotransmitter systems are known to have an important role in the modulation of trigeminal nociception. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00243205183069
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http://dx.doi.org/10.1016/j.lfs.2018.10.059DOI Listing
December 2018
7 Reads

Early postoperative carbamazepine-induced tetany in a patient with trigeminal neuralgia.

J Anaesthesiol Clin Pharmacol 2018 Jul-Sep;34(3):405-406

Department of Neuroanaesthesia, AIIMS, New Delhi, India.

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http://dx.doi.org/10.4103/joacp.JOACP_245_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194827PMC
November 2018
1 Read

Management of Great Auricular Neuralgia Confirmed by Electrophysiologic Examination: A Case Report.

J Oral Facial Pain Headache 2018 Fall;32(32):e53-e56

The great auricular nerve (GAN) is a sensory branch of the cervical plexus originating from the C2 and C3 nerve roots that innervates the external ear, mandibular angle, and parotid gland. Since idiopathic GAN neuralgia is a rare condition and branches of the GAN overlap with other cervical and cranial nerves, its diagnosis is challenging and can be confused with other facial neuralgias. This article describes the case of a 55-year-old woman with intractable unilateral periauricular and lateral head pain. Read More

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October 2018
15 Reads

Pediatric glossopharyngeal neuralgia: a comprehensive review.

Childs Nerv Syst 2018 Oct 25. Epub 2018 Oct 25.

Department of Anatomical Sciences, St. George's University, St. George, Grenada.

Introduction: Debilitating facial pain can seriously affect an individual's daily living. Given that the pathophysiology behind neuropathic and myofascial pain is not fully understood, when chronic facial pain goes undiagnosed, it has been proposed that one of the two is the likely cause. Since their discovery, glossopharyngeal neuralgia (GN) and Eagle's syndrome have been considered mostly conditions afflicting the adult population. Read More

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http://link.springer.com/10.1007/s00381-018-3995-3
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http://dx.doi.org/10.1007/s00381-018-3995-3DOI Listing
October 2018
5 Reads

Modulation of auditory sensory memory by chronic clinical pain and acute experimental pain: a mismatch negativity study.

Sci Rep 2018 Oct 23;8(1):15673. Epub 2018 Oct 23.

CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, 100101, P. R. China.

Pain, especially chronic pain, can lead to cognitive deficits. Mismatch negativity (MMN) is a change-specific component of the auditory event-related brain potential (ERP) that is thought to provide a unique window into sensory memory processes. The present study was designed to determine how chronic and acute pain affects auditory sensory memory. Read More

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http://dx.doi.org/10.1038/s41598-018-34099-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199271PMC
October 2018

Botulinum toxin-A for the treatment of neuralgia: a systematic review and meta-analysis.

J Pain Res 2018 12;11:2343-2351. Epub 2018 Oct 12.

Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China,

Aim: This meta-analysis was performed to evaluate the efficacy and safety of botulinum toxin-A (BTX-A) for the treatment of neuralgia.

Methods: We searched PubMed, EMBASE, and Cochrane databases to identify randomized controlled trials (RCTs) comparing BTX-A treatment with saline for alleviating neuropathic pain. Primary outcome measures were pain scores up to 24 weeks after treatment. Read More

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https://www.dovepress.com/botulinum-toxin-a-for-the-treatmen
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http://dx.doi.org/10.2147/JPR.S168650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6190814PMC
October 2018
9 Reads

Surgical Management of Trigeminal Neuralgia in Children.

World Neurosurg 2019 Jan 19;121:217-221. Epub 2018 Oct 19.

Section of Pediatric Neurosurgery, Riley Hospital for Children, Department of Neurological Surgery, Goodman Campbell Brain and Spine, Indiana University School of Medicine, Indianapolis, Indiana, USA. Electronic address:

Background: Trigeminal neuralgia (TN) is a well-recognized facial pain syndrome. Discrete forms with disparate pain symptoms include classic and atypical. However, atypical facial pain includes neuralgiform pain along a spectrum. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183237
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http://dx.doi.org/10.1016/j.wneu.2018.10.074DOI Listing
January 2019
15 Reads

Nationwide Shift From Percutaneous Rhizotomy to Microvascular Decompression for Treatment of Trigeminal and Other Cranial Nerve Neuralgias.

Headache 2018 Nov 18;58(10):1675-1679. Epub 2018 Oct 18.

Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, UT, USA.

Objective: The aim of this study was to report the trends in the use of common surgical interventions over the past decade to treat cranial nerve neuralgias.

Methods: The Centers for Medicare and Medicaid Services Part B National Summary Data File from 2000 to 2016 were studied.

Results: A total of 57. Read More

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http://dx.doi.org/10.1111/head.13425DOI Listing
November 2018
3 Reads

Different Pain States of Trigeminal Neuralgia Make Significant Changes in the Plasma Proteome and Some Biochemical Parameters: a Preliminary Cohort Study.

J Mol Neurosci 2018 Dec 17;66(4):524-534. Epub 2018 Oct 17.

Department of Statistics, Zanjan University of Medical Sciences, Zanjan, Iran.

Trigeminal neuralgia (TN) with chronic and severe neuropathic pain leads to remarkable interference in daily living activities of patients. Unknown molecular mechanisms involved in TN pathophysiology are a challenge for complete treatment of the disease. The present study was conducted to investigate changes in the plasma proteome beside biochemical parameters, including calcitonin gene-related peptide (CGRP), nitric oxide (NO), amino acids, and vitamin D (Vit D) in different pain states in TN patients. Read More

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http://dx.doi.org/10.1007/s12031-018-1183-2DOI Listing
December 2018

The Exacerbation of Hemicrania Continua Mimics Trigeminal Neuralgia.

Intern Med 2018 Oct 17. Epub 2018 Oct 17.

Department of Neurology and Cerebrovascular Medicine, Saitama Medical University International Medical Center, Japan.

We report the case of a 46-year-old man with hemicrania continua presenting as exacerbations mimicking trigeminal neuralgia. The patient was tentatively diagnosed with trigeminal neuralgia, and treatment with various combinations of drugs was performed after the onset of pain. However, when the condition of the patient did not improve, we suspected hemicrania continua, and treatment with indomethacin was initiated. Read More

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.1561-18DOI Listing
October 2018
11 Reads