8,926 results match your criteria Trigeminal Neuralgia


The Orofacial Pain Clinic Questionnaire (EDOF-HC) in the evaluation and diagnosis of orofacial pain.

Arq Neuropsiquiatr 2020 Jun;78(6):321-330

Universidade de São Paulo, Faculdade de Medicina, Departamento de Neurologia, Clínica de Dor Orofacial, São Paulo SP, Brazil.

Background: Diagnostic tools are necessary for the anamnesis and examination of orofacial pain, in order to fulfill diagnostic criteria and to screen potential causes of pain.

Objective: To evaluate the Orofacial Pain Clinic Questionnaire (EDOF-HC) in the assessment and diagnosis of orofacial pain.

Methods: Overall, 142 patients were evaluated and classified according to the criteria of the International Headache Society and International Association for the Study of Pain. Read More

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http://dx.doi.org/10.1590/0004-282X20200003DOI Listing

Pitfals in recognition and management of trigeminal neuralgia.

J Headache Pain 2020 Jun 30;21(1):82. Epub 2020 Jun 30.

IRCCS Mondino Foundation, Pavia, Italy.

Background: Trigeminal neuralgia (TN) is a severe, disabling form of painful cranial neuropathy. Even though TN has a typical clinical picture, diagnosis it is often missed or delayed in clinical practice. In order to investigate the occurrence of diagnostic and therapeutic errors in TN, we studied 102 patients suffering from TN recruited through a multicentric survey. Read More

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http://dx.doi.org/10.1186/s10194-020-01149-8DOI Listing

Natural dural defect of the posterior fossa dura as a risk factor for postoperative cerebrospinal fluid leakage.

World Neurosurg 2020 Jun 26. Epub 2020 Jun 26.

Department of Neurosurgery, Saitama Medical University Hospital, 38 Morohongo, Moroyama-cho, Iruma-gun, Saitama 350-0495, Japan.

Background: During microvascular decompression surgery (MVD), small (2-3 mm in diameter) natural dural defects have been noticed occasionally but never reported. These tiny dural defects cannot be detected by preoperative imaging studies or even in anatomical cadaver dissection, but may lead to complications including cerebrospinal fluid (CSF) leakage.

Objective: To analyze the features of these natural defects in the posterior fossa dura. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.165DOI Listing

Gamma knife radiosurgery for trigeminal neuralgia: role of trigeminal length and ponto-trigeminal angle on target definition and on clinical effects.

World Neurosurg 2020 Jun 26. Epub 2020 Jun 26.

Department of Neurosurgery and Gamma Knife Radiosurgery, IRCCS San Raffaele Scientific Institute and Vita-Salute University, Milan, Italy. Electronic address:

Objective: Gamma knife radiosurgery (GKRS) is a well-defined treatment for trigeminal neuralgia (TN). The aim of this study is to determine how the GKRS planning might change on the basis of the patient's own anatomy and how to best choose the target location.

Methods: Trigeminal cisternal length, ponto-trigeminal angle and distance between middle of the shot and emergence were evaluated in 112 consecutive GKRS plans for TN. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.147DOI Listing

Case of vago-glossopharyngeal neuralgia secondary to metastatic oropharyngeal cancer.

BMJ Case Rep 2020 Jun 28;13(6). Epub 2020 Jun 28.

Department of Critical Care Medicine, Mayo Clinic, Jacksonville, Florida, USA.

Glossopharyngeal neuralgia (GN) is a rare pain syndrome caused by compression of the glossopharyngeal nerve. It is typically idiopathic and often goes misdiagnosed because of its similarities to trigeminal neuralgia. Vago-glossopharyngeal neuralgia, an even rarer subset of GN, occurs when the pain is accompanied by syncope and/or arrhythmia. Read More

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http://dx.doi.org/10.1136/bcr-2019-232820DOI Listing

The treatment of V2 + V3 idiopathic trigeminal neuralgia using peripheral nerve radiofrequency thermocoagulation via the foramen rotundum and foramen ovale compared with semilunar ganglion radiofrequency thermocoagulation.

Clin Neurol Neurosurg 2020 Jun 17;196:106025. Epub 2020 Jun 17.

Department of Pain Clinic, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, 330006, People's Republic of China. Electronic address:

Objectives: To compare the advantages and disadvantages of V2 + V3 idiopathic trigeminal neuralgia using peripheral nerve radiofrequency (RF) thermocoagulation (PRF) via the foramen rotundum (FR) and foramen ovale (FO) with those of semilunar ganglion RF thermocoagulation (GRF) under local anesthesia, for exploring a new and available surgical method for patients with V2 + V3 idiopathic trigeminal neuralgia.

Patients And Methods: 102 patients with V2 + V3 idiopathic trigeminal neuralgia were enrolled in this prospective randomized controlled clinical trial, and they were divided into the PRF and GRF group randomly (n = 51 in both groups). The outcome of pain relief was assessed using the Barrow Neurological Institute (BNI) pain score, and grouped as good (BNI Class I or II, no medication required) and bad (BNI Class III-V, medication required or failed). Read More

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http://dx.doi.org/10.1016/j.clineuro.2020.106025DOI Listing

Factors associated with long-term risk of recurrence after percutaneous radiofrequency thermocoagulation of the gasserian ganglion for patients with trigeminal neuralgia involving the ophthalmic division: A retrospective study.

Pain Pract 2020 Jun 25. Epub 2020 Jun 25.

Department of Pain Management, Xuanwu Hospital of Capital Medical University, Beijing, China, 100053.

Objective: To evaluate risk factors associated with recurrence after radiofrequency thermocoagulation (RFT) of gasserian ganglion among patients with ophthalmic trigeminal neuralgia (TN) and prognostic factors in terms of recurrence-free survival (RFS) during a long-term follow-up.

Methods: From January 2005 to December 2017, 300 patients with ophthalmic TN underwent RFT. A retrospective analysis of 14-year outcomes was performed. Read More

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http://dx.doi.org/10.1111/papr.12930DOI Listing

Neuropathic pain: From mechanisms to treatment.

Physiol Rev 2020 Jun 25. Epub 2020 Jun 25.

Molecular Pharmacology, Institute for Pharmacology, Heidelberg University, Germany.

Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a common chronic pain condition with major impact on quality of life. Examples include trigeminal neuralgia, painful polyneuropathy, postherpetic neuralgia and central poststroke pain. Most patients complain of an ongoing or intermittent spontaneous pain of e. Read More

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http://dx.doi.org/10.1152/physrev.00045.2019DOI Listing

Postoperative Recurrence of Trigeminal Neuralgia with Brown Spots on the Nerve Root.

J Coll Physicians Surg Pak 2020 May;30(5):555

Department of Neurosurgery, Weihai Central Hospital, The Affiliated Hospital of Qingdao University Medical College, Weihai City, China.

Null. Read More

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http://dx.doi.org/10.29271/jcpsp.2020.05.555DOI Listing

Herbal medicine for the management of idiopathic trigeminal neuralgia: A protocol for a systematic review of controlled trials.

Medicine (Baltimore) 2020 Jun;99(25):e20779

Bogwang Korean Medical Clinic, Seoul, Republic of Korea.

Background: Trigeminal neuralgia is an oral facial pain that is limited to one or more parts of the trigeminal nerve. As it becomes chronic, it can seriously affect the quality of life of most patients, and it is expected to increase in incidence in modern aging society. The objective of this systematic review protocol is to provide methods for evaluating the effectiveness and safety of herbal medicines for idiopathic trigeminal neuralgia (ITN). Read More

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http://dx.doi.org/10.1097/MD.0000000000020779DOI Listing

Neuropathy mimicking dental pain on a patient diagnosed with Lyme disease.

J Endod 2020 Jun 17. Epub 2020 Jun 17.

Associate Professor, Department of Dental Clinical Sciences, Faculty of Dentistry, Dalhousie University, Halifax, NS, Canada.

This report documents a case of a patient who developed neuropathy, which presented as dental pain and was later diagnosed with Lyme disease. A healthy female patient presented to the endodontist with toothache symptoms. Her symptoms included intense pain in the left mandible irradiating into the temporalis area and through her neck, tingling on the lower left lip and left side of her tongue. Read More

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http://dx.doi.org/10.1016/j.joen.2020.06.011DOI Listing

Current application of cannabidiol (CBD) in the management and treatment of neurological disorders.

Neurol Sci 2020 Jun 16. Epub 2020 Jun 16.

Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.

Cannabidiol (CBD), which is nonintoxicating pharmacologically relevant constituents of Cannabis, demonstrates several beneficial effects. It has been found to have antioxidative, anti-inflammatory, and neuroprotective effects. As the medicinal use of CBD is gaining popularity for treatment of various disorders, the recent flare-up of largely unproven and unregulated cannabis-based preparations on medical therapeutics may have its greatest impact in the field of neurology. Read More

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http://dx.doi.org/10.1007/s10072-020-04514-2DOI Listing

Increased CSF levels of apolipoproteins and complement factors in trigeminal neuralgia patients - in depth proteomic analysis using mass spectrometry.

J Pain 2020 Jun 14. Epub 2020 Jun 14.

Department of Medical Sciences, Chemical Chemistry, Uppsala University, Uppsala, Sweden.

The main cause of trigeminal neuralgia (TN) is compression of a blood vessel at the root entry zone of the trigeminal nerve. However, a neurovascular conflict does not seem to be the only etiology and other mechanisms are implicated in the development of the disease. We hypothesized that TN patients may have distinct protein expression in the CSF. Read More

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http://dx.doi.org/10.1016/j.jpain.2020.03.002DOI Listing

A case report of microvascular decompression for cervical myelopathy and radiculopathy caused by tortuous and abnormal bilateral vertebral artery.

Surg Neurol Int 2020 30;11:136. Epub 2020 May 30.

Department of Neurosurgery, Tanabe Hospital, Fujiidera City, Osaka, Japan.

Background: Tortuous/abnormal vertebral arteries (VAs) sometimes cause neurovascular compression syndromes (NVCs), such as trigeminal neuralgia, hemifacial spasm, and, rarely, myelopathy/radiculopathy. Abnormalities/tortuosity of the VA at the level of the atlas and axis are of particular note; these may be characterized by a persistent first intersegmental artery (PFIA) and C2 segmental type of VA. Herein, we report a 72-year-old male who presented with cervical myelopathy/radiculopathy due to bilateral tortuosity of the PFIA resulting in spinal cord compression at the craniocervical junction. Read More

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http://dx.doi.org/10.25259/SNI_240_2020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294169PMC

Intraoperative CT for Neuronavigation Guidance and Confirmation of Foramen Ovale Cannulation for Glycerol Trigeminal Rhizotomy: A Technical Report and Case Series.

Cureus 2020 May 13;12(5):e8100. Epub 2020 May 13.

Neurosurgery, University of Louisville School of Medicine, Louisville, USA.

Glycerol rhizotomy was originally described as an initial surgical treatment for trigeminal neuralgia after the failure of medical therapy. Here we describe its use as a salvage procedure, typically after failure of multiple other modalities including microvascular decompression, stereotactic radiosurgery, and/or other percutaneous procedures. Foramen ovale cannulation as a "salvage procedure" may be complicated by lack of cerebrospinal fluid (CSF) return despite adequate cannulation of the foramen ovale, making conventional fluoroscopic confirmation of adequate needle placement less certain. Read More

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http://dx.doi.org/10.7759/cureus.8100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292704PMC

Imaging of orofacial pain.

J Oral Pathol Med 2020 Jun 12. Epub 2020 Jun 12.

Perth Radiological Clinic, Subiaco, WA, Australia.

Background: Orofacial pain is a common complaint, with an estimated 75% of cases caused by dental disease, specifically a diseased pulp. A small percentage of orofacial pain cases will require specialist referral most commonly to oral medicine specialists or oral and maxillofacial surgeons from a dental perspective, or otolaryngologists or neurologists from a medical perspective.

Imaging Modalities: Following a thorough history and clinical examination, imaging is often required to narrow the differential diagnosis or answer a specific query related to the final diagnosis. Read More

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http://dx.doi.org/10.1111/jop.13063DOI Listing

The historical evolution of microvascular decompression for trigeminal neuralgia: from Dandy's discovery to Jannetta's legacy.

Acta Neurochir (Wien) 2020 Jun 9. Epub 2020 Jun 9.

Department of Neurological Surgery, Neurological Institute of New Jersey, Rutgers New Jersey Medical School, 90 Bergen Street, Suite 8100, Newark, NJ, 07103, USA.

Although the symptoms of trigeminal neuralgia (TN) have been well described throughout the history of medicine, its etiology was initially not well understood by most surgeons. The standard procedure used to treat TN today, microvascular decompression (MVD), evolved due to the efforts of numerous neurosurgeons throughout the twentieth century. Walter Dandy was the first to utilize the cerebellar (suboccipital) approach to expose the trigeminal nerve for partial sectioning. Read More

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http://dx.doi.org/10.1007/s00701-020-04405-7DOI Listing

Acupuncture in the management of trigeminal neuralgia.

Acupunct Med 2020 Jun 10:964528420924042. Epub 2020 Jun 10.

School of Medical Sciences, Bangor University, Bangor, UK.

Background: We aimed to assess the standing of acupuncture as a clinical tool in the management of trigeminal neuralgia against the current first-line drug treatment (carbamazepine) and the most effective surgery (microvascular decompression (MVD)).

Methods: Data regarding efficacy, side effects and cost were compiled for each of these three modalities from the PubMed and Cochrane Library databases. Patient stress was estimated according to Holmes and Rahe's Social Readjustment Rating Scale (SRRS). Read More

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http://dx.doi.org/10.1177/0964528420924042DOI Listing

Computed Tomography-Guided Radiofrequency Thermocoagulation of the Gasserian Ganglion Using an Alternative to Hartel Anterior Approach: A Bicentral Study.

Pain Physician 2020 Jun;23(3):293-298

Department of Interventional Radiology, Athens Naval Hospital, Athens, Greece.

Background: Trigeminal neuralgia (TN) is associated with multiple mechanisms involving peripheral and central nervous system pathologies. Among percutaneous treatments offered, radiofrequency thermocoagulation (RFT) is associated with longer duration of pain relief. Mostly due to anatomic variation, cannulation of the foramen ovale using the Hartel approach has a failure rate of 5. Read More

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c-Abl-p38 signaling pathway mediates dopamine neuron loss in trigeminal neuralgia.

Mol Pain 2020 Jan-Dec;16:1744806920930855

Department of Pain, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Trigeminal neuralgia is a common neuropathic pain in the head and face. The pathogenesis of trigeminal neuralgia is complex, and so far, the pathogenesis of trigeminal neuralgia involving peripheral and central nervous inflammation theory has not been explained clearly. The loss of dopamine neurons in striatum may play an important role in the development of trigeminal nerve, but the reason is not clear. Read More

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http://dx.doi.org/10.1177/1744806920930855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7278317PMC

The Effect of Atropine on Trigeminocardiac Reflex-induced Hemodynamic Changes During Therapeutic Compression of the Trigeminal Ganglion.

J Neurosurg Anesthesiol 2020 Jun 2. Epub 2020 Jun 2.

Second Department of Neurosurgery, People's Hospital of China Medical University (Liaoning Provical People's Hospital).

Background: Percutaneous compression of the trigeminal ganglion (PCTG) can induce significant hemodynamic perturbations secondary to the trigeminocardiac reflex (TCR). The aim of this study was to investigate the effect of atropine pretreatment on hemodynamic responses during PCTG for trigeminal neuralgia.

Materials And Methods: A total of 120 patients who received PCTG were randomly assigned to control and atropine groups that were pretreated with saline (n=60) and atropine 0. Read More

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http://dx.doi.org/10.1097/ANA.0000000000000702DOI Listing
June 2020
2.990 Impact Factor

Anosmia and Ageusia as the Only Indicators of Coronavirus Disease 2019 (COVID-19).

Cureus 2020 May 1;12(5):e7918. Epub 2020 May 1.

Library Science, Abington Hospital-Jefferson Health, Abington, USA.

The patient is a 60-year-old woman with a history of vertigo and seasonal allergies who presented to the hospital with the chief complaint of headache. Radiological findings were negative for intracranial abnormalities. The headache was due to trigeminal neuralgia. Read More

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http://dx.doi.org/10.7759/cureus.7918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263711PMC

Surgical treatment of secondary trigeminal neuralgia induced by cerebellopontine angle tumors: A single-center experience.

World Neurosurg 2020 May 31. Epub 2020 May 31.

Department of Neurosurgery, PLA 960th hospital, 25 Shifan Road, Jinan 250031, Shandong Province, China.

Objective: Secondary trigeminal neuralgia (TN) caused by cerebellopontine angle (CPA) tumors are rare. However, TN may be a primary manifestation in the neurosurgery department. In this study, we aimed to retrospectively assess patients with CPA tumor-induced TN from a single center. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.226DOI Listing

CT-guided infiltration of greater occipital nerve for refractory craniofacial pain syndromes other than occipital neuralgia.

Diagn Interv Imaging 2020 May 29. Epub 2020 May 29.

Adult Radiology Department, Necker Hospital, Assistance-Publique-Hopitaux de Paris, Université de Paris, 75006 Paris, France.

Purpose: The purpose of this study was to evaluate the effectiveness of computed tomography (CT)-guided infiltration of greater occipital nerve (GON) for the treatment of refractory craniofacial pain syndromes other than occipital neuralgia.

Materials And Methods: Fifty-six patients suffering from refractory craniofacial pain syndromes were included between 2011 and 2017. There were 33 women and 23 men with a mean age of 50. Read More

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http://dx.doi.org/10.1016/j.diii.2020.05.006DOI Listing

Augmented Visualization Surgical Microscope Assisted Microvascular Decompression for Hemifacial Spasm.

Otol Neurotol 2020 May 28. Epub 2020 May 28.

University of Connecticut, School of Medicine, Farmington, Connecticut.

: Microvascular decompression (MVD) is curative treatment for primary Hemifacial Spasm, in cases where a vascular loop impinges on the facial nerve. Surgical techniques for MVD may be extended to MVD of the glossopharyngeal nerve and trigeminal nerve in cases of primary glossopharyngeal neuralgia and trigeminal neuralgia. Stroke is a rare complication of these procedures that may occur during the separation of a vascular loop from nervous tissue, particularly when materials such as Teflon are used to separate the structures. Read More

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http://dx.doi.org/10.1097/MAO.0000000000002717DOI Listing

Outcomes of Treatment for Elderly Patients With Trigeminal Neuralgia: Percutaneous Balloon Compression Versus Microvascular Decompression.

J Craniofac Surg 2020 May 28. Epub 2020 May 28.

Department of Emergency, Suqian People's Hospital of Nanjing Drum-Tower Hospital Group, Suqian, China.

Objective: The study aimed to evaluate the surgical outcomes of percutaneous balloon compression (PBC) and microvascular decompression (MVD) in the treatment of elderly patients with trigeminal neuralgia (TN).

Methods: A total of 30 patients who underwent PBC surgery (PBC group) and 30 patients who received MVD surgery (MVD group) were included. The treatment efficacy, Barrow Neurological Institute (BNI) pain intensity score, inflammatory response, the rates of complication and recurrence were analyzed respectively. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006544DOI Listing

Sporadic Creutzfeldt-Jakob Disease: Case Report and Literature Review.

Cureus 2020 Apr 21;12(4):e7767. Epub 2020 Apr 21.

Neurology, Marcus Neuroscience Institute, Boca Raton Regional Hospital, Boca Raton, USA.

The proverbial "zebras" in neurology are often times missed due to their low prevalence and incidence in the community. The number of misdiagnoses and improper therapeutic interventions that occur are further increased when patients with these rare diseases present with signs and symptoms of more common disorders. One such disease is sporadic Creutzfeldt-Jakob disease (sCJD), a prion disease that causes neuronal derangement and classically presents as a rapidly progressing dementia with extrapyramidal signs, ataxia, behavioural problems, and myoclonus in the advanced stage. Read More

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http://dx.doi.org/10.7759/cureus.7767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243655PMC

Intracranial Leiomyoma Associated with Epstein-Barr Virus: a cerebellopontine angle mass presenting with trigeminal neuralgia.

World Neurosurg 2020 May 22. Epub 2020 May 22.

Department of Neurosurgery, University of Illinois at Chicago.

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http://dx.doi.org/10.1016/j.wneu.2020.05.157DOI Listing
May 2020
2.417 Impact Factor

Development and Validation of a Free Carbamazepine Assay on an Automated Chemistry Analyzer.

J Appl Lab Med 2020 Mar;5(2):357-362

Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH.

Background: Carbamazepine is an effective drug for treating seizures and trigeminal neuralgia. Therapeutic drug monitoring of free carbamazepine in serum can be useful in situations that drug--protein binding is altered to guide regimen adjustment and to aid in the diagnosis of clinical toxicity.

Methods: Separation of the nonprotein bound carbamazepine was achieved via ultrafiltration through a molecular weight cut-off filter. Read More

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http://dx.doi.org/10.1093/jalm/jfz003DOI Listing

Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study.

Radiat Oncol 2020 May 22;15(1):115. Epub 2020 May 22.

Brain Radiosurgery, CDI Centro Diagnostico Italiano, Milan, Italy.

Background: Stereotactic radiosurgery (SRS) is an effective treatment for trigeminal neuralgia (TN). Nevertheless, a proportion of patients will experience recurrence and treatment-related sensory disturbances. In order to evaluate the predictors of efficacy and safety of image-guided non-isocentric radiosurgery, we analyzed the impact of trigeminal nerve volume and the nerve dose/volume relationship, together with relevant clinical characteristics. Read More

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http://dx.doi.org/10.1186/s13014-020-01535-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243318PMC

Efficacy and Safety of Percutaneous Ozone Injection Around Gasserian Ganglion for the Treatment of Trigeminal Neuralgia: A Multicenter Retrospective Study.

J Pain Res 2020 4;13:927-936. Epub 2020 May 4.

Department of Anesthesiology, Weifang Medical University, Weifang City 261000, Shangdong, People's Republic of China.

Background: Ozone injection around Gasserian ganglion (OIAGG) has been reported to be an effective treatment for trigeminal neuralgia (TN); however, there remain areas for improvement. To overcome one of these limitations, a multicenter examination of application would be extremely helpful.

Objective: The goal of this report was to assess the efficacy of OIAGG for refractory TN across multiple centers and to explore factors predictive of successful treatment. Read More

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http://dx.doi.org/10.2147/JPR.S232081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210028PMC

Diffusion tensor imaging reveals microstructural alteration of the trigeminal nerve root in classical trigeminal neuralgia without neurovascular compression and correlation with outcome after internal neurolysis.

Magn Reson Imaging 2020 May 19;71:37-44. Epub 2020 May 19.

Department of Neurosurgery, The First Affiliated Hospital of USTC (Anhui Provincial Hospital), Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, PR China; Anhui Provincial Stereotactic Neurosurgical Institute, Hefei, Anhui, 230001, PR China; Anhui Provincial Key Laboratory of Brain Function and Disease, Hefei, Anhui, 230001, PR China.

Objectives: Diffusion tensor imaging (DTI) has been used to detect microstructural alteration and effect of surgical treatment of the trigeminal nerve root (TR) in patients with classical trigeminal neuralgia (CTN) underwent microvascular decompression (MVD). Patients with CTN without neurovascular compression (woNVC) is a special population of TN, however, the pathogenesy of CTN woNVC and the mechanism of internal neurolysis (IN) remain unknown.

Materials And Methods: 21 patients with CTN woNVC who underwent IN and 20 healthy controls were included in this study. Read More

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http://dx.doi.org/10.1016/j.mri.2020.05.006DOI Listing

[Microvascular Decompression to Treat Abducens Nerve Paralysis Caused by Compression of the Anterior Inferior Cerebellar Artery:A Case Report].

No Shinkei Geka 2020 May;48(5):429-434

Department of Neurosurgery, Faculty of Medicine, Fukuoka University.

Microvascular decompression(MVD)is an effective treatment for hemifacial spasm and trigeminal neuralgia. However, there are few reports regarding its use with abducens nerve palsy. Here, we report the case of a 77-year-old male who presented with diplopia and was admitted to our facility for right abducens nerve palsy. Read More

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http://dx.doi.org/10.11477/mf.1436204205DOI Listing

Spontaneous Carotid Artery Dissection Presenting as Trigeminal Neuralgia in the Emergency Department.

Clin Pract Cases Emerg Med 2020 May 14;4(2):255-258. Epub 2020 Apr 14.

Midwestern University, Chicago College of Osteopathic Medicine, Department of Emergency Medicine, Downers Grove, Illinois.

Introduction: Carotid artery dissection (CAD) is a critical diagnosis in the emergency department (ED). Trigeminal neuralgia, while not uncommon, may cause the patient significant discomfort but generally is not attributed to severe morbidity and mortality.

Case Report: We present a case of spontaneous CAD presenting with the classic intermittent "lightning-like" jaw and head pain suggestive of trigeminal neuralgia that was ultimately diagnosed utilizing computed tomography angiogram after multiple visits to the ED. Read More

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http://dx.doi.org/10.5811/cpcem.2020.1.44664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220000PMC

MR-Guided Focused Ultrasound Central Lateral Thalamotomy for Trigeminal Neuralgia. Single Center Experience.

Front Neurol 2020 17;11:271. Epub 2020 Apr 17.

SoniModul, Center for Ultrasound Functional Neurosurgery, Solothurn, Switzerland.

Trigeminal neuralgia (TN) is a recognized pain condition the treatment of which can be very challenging. Various surgical interventions can be applied in cases of therapy-resistance to drug treatments. The central lateral thalamotomy (CLT) against neurogenic (or neuropathic) pain is based on multiarchitectonic histological as well as physiopathological studies, and integrates the nucleus in a large thalamocortical (TC) and corticocortical network responsible for the sensory, cognitive and affective/emotional components of pain. Read More

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http://dx.doi.org/10.3389/fneur.2020.00271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212452PMC

A systematic review on persistent trigeminal artery, in searching for a therapeutic solution to idiopathic and unresponsive trigeminal nerve inflammations and migraines.

J Biol Regul Homeost Agents 2019 Nov-Dec;33(6 Suppl. 2):155-169

Pham Ngoc Thac University of Medicine, Department of Histology, Embryology and Genetics, Ho Chi Minh City, Vietnam.

The rarely diagnosed persistent trigeminal artery (PTA) originates from the posterior bend or lateral wall of the intracavernous carotid artery and is the most common occurring type of remnant primitive fetal arteries. Even if PTA is uncommon, information and awareness about it could be of great help for clinicians dealing with cranial vascular imaging and operating this region. In addition, it could give a supporting response to the presence of a wide range of idiopathic and unresponsive disturbs that sometimes are erroneously interpreted and treated. Read More

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Trigeminal Trophic Syndrome Secondary to Refractory Trigeminal Neuralgia Treated with CyberKnife® Radiosurgery.

Cureus 2020 Apr 14;12(4):e7670. Epub 2020 Apr 14.

Radiation Oncology, Cyberknife Centre, Ruber Internacional, Madrid, ESP.

Trigeminal trophic syndrome (TTS) is a rare condition in which there is the involvement of the skin innervated by branches of the trigeminal nerve. Because of an alteration in the sensory function of the trigeminal nerve, an exaggerated manipulation of the skin by the patient occurs, with secondary ulcers in the affected areas. They are usually unilateral and located mainly at the beginning of the nose wing. Read More

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http://dx.doi.org/10.7759/cureus.7670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226666PMC

Mechanism underlying cranial nerve rhizopathy.

Med Hypotheses 2020 May 6;142:109801. Epub 2020 May 6.

Dept. Neurosurgery, XinHua Hospital, Shanghai JiaoTong University School of Medicine, 1665 KongJiang Rd., Shanghai 200092, China. Electronic address:

The cranial nerve rhizophathy, commonly presented with trigeminal neuralgia (TN) or hemifacial spasm (HFS), is a sort of hyperexcitability disorders with higher incidence in senior Asian. In this paper, a novel hypothesis on the pathogenesis is proposed and with which some clinical phenomena are explained. In those with crowded cerebellopontine angle in anatomy, the cranial nerve root and surrounding vessel are getting closer and closer to each other with aging and finally the neurovascular conflict happens. Read More

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http://dx.doi.org/10.1016/j.mehy.2020.109801DOI Listing

The risk of mastication weakness after percutaneous balloon compression for the treatment of trigeminal neuralgia.

Clin Neurol Neurosurg 2020 May 4;195:105880. Epub 2020 May 4.

Department of Neuroscience, Neurosurgery Section, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1016/j.clineuro.2020.105880DOI Listing

Delayed Contralateral Trigeminal Neuralgia After Microvascular Decompression and Postoperative Changes in Venous Outflow.

World Neurosurg 2020 May 12;140:107-108. Epub 2020 May 12.

Macquarie Neurosurgery, Department of Clinical Medicine, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia; Computational NeuroSurgery Laboratory, Department of Clinical Medicine, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia.

A 66-year-old woman had presented with a 3-month history of left trigeminal neuralgia. She had undergone successful microvascular decompression for right-sided trigeminal neuralgia 8 years previously. To optimize visualization, microvascular decompression for trigeminal neuralgia has been commonly associated with sacrifice of the superior petrosal vein during surgery. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.041DOI Listing

The Successful Treatment of Severe Trigeminal Neuralgia by a Single Mandibular Nerve Block and Subsequent Natalizumab Administration in a Patient with Multiple Sclerosis.

Cureus 2020 Apr 12;12(4):e7646. Epub 2020 Apr 12.

Neurology, Tokyo Metropolitan Neurological Hospital, Tokyo, JPN.

We report the case of a middle-aged woman who developed trigeminal neuralgia as a sequela of multiple sclerosis (MS). The trigeminal neuralgia was refractory to medications and persisted for two years. Eventually, it was resolved by a mandibular nerve block followed by natalizumab administration. Read More

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http://dx.doi.org/10.7759/cureus.7646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217241PMC

Cerebellopontine Angle Lipoma Manifesting as Trigeminal Neuralgia.

J Pediatr 2020 Jul 6;222:250. Epub 2020 May 6.

Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.

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http://dx.doi.org/10.1016/j.jpeds.2020.03.037DOI Listing

Orofacial pain secondary to acoustic neuroma-A case report.

Spec Care Dentist 2020 May 8;40(3):303-307. Epub 2020 May 8.

Department of Restorative Dentistry, Federal University of Ceará, Fortaleza, Ceará, Brazil.

Aim: The present study aimed to report a case of orofacial pain secondary to acoustic neuroma (AN).

Methods And Results: A 66-year-old female presented with unilateral facial pain and odontalgia. The pain was described as throbbing, dull, and constant. Read More

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http://dx.doi.org/10.1111/scd.12461DOI Listing

Predictors of the Analgesic Efficacy of CT-Guided Percutaneous Pulsed Radiofrequency Treatment of Gasserian Ganglion in Patients With Idiopathic Trigeminal Neuralgia.

Pain Pract 2020 May 7. Epub 2020 May 7.

Department of Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Aims: Although pulsed radiofrequency (PRF) has few postoperative adverse reactions, its analgesic efficacy for trigeminal neuralgia (TN) is not always guaranteed. The response rate of PRF targeting the Gasserian ganglion for patients with TN varies. This study aims to identify the predictors of the analgesic efficacy of CT-guided percutaneous PRF in patients with idiopathic TN. Read More

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http://dx.doi.org/10.1111/papr.12910DOI Listing

Increased risk of tinnitus following a trigeminal neuralgia diagnosis: a one-year follow-up study.

J Headache Pain 2020 May 6;21(1):46. Epub 2020 May 6.

Department of Health Care Administration, Taipei Medical University, 250 Wu-Hsing St, Taipei, 110, Taiwan.

Background: Tinnitus due to hyperactivity across neuronal ensembles along the auditory pathway is reported. We hypothesized that trigeminal neuralgia patients may subsequently suffer from tinnitus. Using nationwide, population-based data and a retrospective cohort study design, we investigated the risk of tinnitus within 1 year following trigeminal neuralgia. Read More

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http://dx.doi.org/10.1186/s10194-020-01121-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203585PMC

Local Administration of Methylcobalamin for Subacute Ophthalmic Herpetic Neuralgia: A Randomized, Phase III Clinical Trial.

Pain Pract 2020 May 6. Epub 2020 May 6.

Rehabilitation Medicine Department, Chongming Branch of Shanghai Tenth People's Hospital, Shanghai, China.

Objectives: The ophthalmic branch of the trigeminal nerve is one of the most frequently involved sites of postherpetic neuralgia. A single-center randomized controlled study was conducted to evaluate the efficacy of local methylcobalamin injection for subacute ophthalmic herpetic neuralgia (SOHN).

Methods: One hundred and five patients with a pain score of 4 or greater were randomized to receive a combination of methylcobalamin and lidocaine via local injection (LM group, n = 35), intramuscular methylcobalamin and local lidocaine injection (IM group, n = 35), and oral methylcobalamin tablet and lidocaine local injection (OM group, n = 35) for 4 weeks. Read More

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http://dx.doi.org/10.1111/papr.12909DOI Listing
May 2020
2.361 Impact Factor

Microvascular decompression: incidence and prevention of postoperative CSF leakage in a consecutive series of 134 patients.

Br J Neurosurg 2020 May 2:1-3. Epub 2020 May 2.

James Cook University Hospital, Middlesbrough, United Kingdom of Great Britain and Northern Ireland.

Microvascular decompression (MVD) is an established procedure for treating Trigeminal Neuralgia and Hemifacial Spasm. Postoperative CSF leakage is still a common complication after MVD. We did a retrospective study of 134 patients who underwent microvascular decompression, mainly for Trigeminal Neuralgia and Hemifacial Spasm in our unit. Read More

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http://dx.doi.org/10.1080/02688697.2020.1749989DOI Listing

Ruptured dermoid cyst in the Meckel's cave presenting with trigeminal neuralgia in a pediatric patient: a case report.

Childs Nerv Syst 2020 May 2. Epub 2020 May 2.

Division of Pediatric Neurosurgery, Hospital de Pediatría Juan P. Garrahan, Combate de los Pozos 1881, 1245, Buenos Aires, Argentina.

Intracranial dermoid cysts are benign congenital slow growing masses. They account for less than 1% of all primary intracranial lesions. They can be asymptomatic and appear incidentally on brain images. Read More

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http://dx.doi.org/10.1007/s00381-020-04646-yDOI Listing

Surgical Treatment of Symptomatic Small Medial Petrous Meningiomas Causing Trigeminal Neuralgia.

World Neurosurg 2020 Apr 29. Epub 2020 Apr 29.

Department of Neurosurgery, University of Arkansas Medical Sciences, Little Rock, Arkansas, USA. Electronic address:

Background: Symptomatic trigeminal neuralgia caused by small (<3 cm) skull base meningiomas is treated by radiosurgery or surgical resection. Although radiosurgery is less invasive, surgical resection provides more rapid resolution of symptoms. We reviewed a short series of patients who underwent an anterior transpetrosal approach for surgical resection of meningiomas causing trigeminal neuralgia. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.04.127DOI Listing

Surgical Management of the Trigeminocerebellar Artery in Microvascular Decompression for Trigeminal Neuralgia.

Oper Neurosurg (Hagerstown) 2020 May 1. Epub 2020 May 1.

Department of Neurosurgery, Koto Memorial Hospital, Higashiohmi, Japan.

Background: The trigeminocerebellar artery (TCA) is a variant branch of the basilar artery supplying the trigeminal nerve root and cerebellar hemisphere, which may contribute to trigeminal neuralgia (TGN). Despite its unique anatomic description, information regarding the preoperative diagnosis and surgical management of TCA is lacking.

Objective: To evaluate our preoperative diagnosis of TCA using 3-dimensional (3D) images and surgical management of TGN cases with TCA involvement. Read More

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http://dx.doi.org/10.1093/ons/opaa097DOI Listing