2,612 results match your criteria Tricuspid Valve Disease Imaging

The Relationship between Arterial Elasticity Parameters of Ascending Aorta, Abdominal Aorta and Carotid Arteries with Carotid Intima Media Thickness in Children with Bicuspid Aortic Valve.

Anatol J Cardiol 2022 06;26(6):466-475

Department of Pediatric Cardiology, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey.

Background: Bicuspid aortic valve is a congenital cardiac malformation that affects not only the valve and ascending aorta but also the abdominal aorta and large central arter-ies like carotid arteries by damaging the elasticity of the vessel resulting in increased stiffness and reduced distensibility. Deterioration of aortic compliance disturbs functions of the left ventricle and triggers atherosclerosis determined with carotid intima-media thickness. The aim of this study was to assess the effect of the bicuspid aortic valve on the elastic properties of these parts of the arterial system in children. Read More

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Prediction of Aortic Stenosis Progression by F-FDG and F-NaF PET/CT in Different Aortic Valve Phenotypes.

Front Pharmacol 2022 24;13:909975. Epub 2022 May 24.

Non-coronary Heart Disease Department, Almazov National Medical Research Centre, Saint Petersburg, Russia.

Different imaging techniques, such as echocardiography (ECHO) and CT, allow to assess aortic stenosis (AS) severity and could be used to study its progression. But only PET/CT open opportunities to assess activity of valvular inflammation and calcification . The aim of this study was to assess prognostic value of valvular inflammation and calcification measured by F-FDG and F-NaF PET/CT in patients with tricuspid (TAV) and bicuspid aortic valve (BAV). Read More

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Prevalence and Natural History of Mitral Annulus Calcification and Related Valve Dysfunction.

Mayo Clin Proc 2022 Jun;97(6):1094-1107

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address:

Objective: To evaluate the prevalence and natural history of mitral annulus calcification (MAC) and associated mitral valve dysfunction (MVD) in patients undergoing clinically indicated echocardiography.

Methods: A retrospective review was conducted of all adults who underwent echocardiography in 2015. Mitral valve dysfunction was defined as mitral regurgitation or mitral stenosis (MS) of moderate or greater severity. Read More

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CT in Transcatheter-delivered Treatment of Valvular Heart Disease.

Radiology 2022 Jul 31;304(1):4-17. Epub 2022 May 31.

From the Division of Cardiovascular Imaging, Department of Radiology and Radiological Science (P.N.R., U.J.S., J.R.B., T.E., A.V.S.), and Department of Cardiology (N.S.A., D.H.S., R.R.B.), Medical University of South Carolina, 25 Courtenay Dr, MSC 226, Charleston, SC 29425; Department of Coronary and Structural Heart Diseases, National Institute of Cardiology, Warsaw, Poland (P.N.R., M.D., C.K.); Department of Radiology for Providence Health Care, Vancouver Coastal Health, Vancouver, Canada (J.A.L.); Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland (D.D.); Maria Cecilia Hospital, GVM Care & Research, Cotignola (RA), Ravenna, Italy (D.D.); Department of Diagnostic and Interventional Radiology, Universitätsklinikum Augsburg, Augsburg, Germany (F.S.); Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria (M.A.); Department of Measurement and Electronics, AGH University of Science and Technology, Krakow, Poland (A.Z.H.); Department of Cardiology, Medizinische Klinik I, RoMed Klinikum Rosenheim, Rosenheim, Germany (C.T.); Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany (M.R.); and Department of Radiology, Poznan University of Medical Sciences, Poznan, Poland (P.P.).

Minimally invasive strategies to treat valvular heart disease have emerged over the past 2 decades. The use of transcatheter aortic valve replacement in the treatment of severe aortic stenosis, for example, has recently expanded from high- to low-risk patients and became an alternative treatment for those with prohibitive surgical risk. With the increase in transcatheter strategies, multimodality imaging, including echocardiography, CT, fluoroscopy, and cardiac MRI, are used. Read More

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Clinicopathological features of adult right-sided cardiac masses: Analysis of 19 cases.

Ann Med Surg (Lond) 2022 May 10;77:103613. Epub 2022 Apr 10.

Department of Cardiology, Laboratory of Epidemiology, Clinical Research and Public Health, Medical School, University Mohammed the First, Oujda, Morocco.

Background: Right sided cardiac masses are rare. The purpose of this study is to review the clinical experience and pathological characteristics of right-sided cardiac masses and to provide a prognostic analysis in our hospital.

Methods: We retrospectively reviewed 19 consecutive cases of right heart masses diagnosed in our institution from 2016 to February 2020. Read More

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Global Aortic Pulse Wave Velocity is Unchanged in Bicuspid Aortopathy With Normal Valve Function but Elevated in Patients With Aortic Valve Stenosis: Insights From a 4D Flow MRI Study of 597 Subjects.

J Magn Reson Imaging 2022 May 28. Epub 2022 May 28.

Radiology, Northwestern University, Chicago, Illinois, USA.

Background: Aortopathy is common with bicuspid aortic valve (BAV), and underlying intrinsic tissue abnormalities are believed causative. Valve-mediated hemodynamics are altered in BAV and may contribute to aortopathy and its progression. The contribution of intrinsic tissue defects versus altered hemodynamics to aortopathy progression is not known. Read More

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Infective Endocarditis Presenting with Embolic Splenic and Renal Infarcts and Spinal Discitis.

Case Rep Infect Dis 2022 14;2022:7183049. Epub 2022 May 14.

Department of Internal Medicine, Riverside University Health System Medical Center, Moreno Valley, California, USA.

(. ) is a Gram-positive, coagulase-negative bacteria that occurs as a normal commensal organism on the skin and may rarely cause native valve endocarditis (NVE). We present a 62-year-old male with type 2 diabetes mellitus, coronary artery disease, and hypertension presenting with fever and abdominal pain. Read More

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Mechanistic Insights into Tricuspid Regurgitation Secondary to Pulmonary Arterial Hypertension.

Am J Cardiol 2022 Jul 18;175:97-105. Epub 2022 May 18.

Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio. Electronic address:

The simultaneous presence of pulmonary arterial hypertension (PAH) and secondary tricuspid regurgitation (STR) portends particularly poor outcomes. However, not all patients with PAH develop significant STR, and the mechanisms and clinical implications underlying this phenomenon remain unclear. We sought to describe the functional, anatomic, hemodynamic, and clinical characteristics of patients with PAH with and without STR. Read More

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Moyamoya Disease Complicating Ebstein's Anomaly.

Intern Med 2022 May 14. Epub 2022 May 14.

Department of Cardiology and Nephrology, Mie University Graduate School of Medicine, Japan.

Ebstein's anomaly is an uncommon congenital disorder affecting the tricuspid valve. We herein report a 38-year-old woman who experienced consciousness and sensory disturbance during treatment for heart failure caused by Ebstein's anomaly. Urgent magnetic resonance imaging and cerebral angiography demonstrated acute cerebral infarction and internal carotid artery obstruction with the development of collateral arteries. Read More

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To repair or not to repair: the dilemma of tricuspid regurgitation associated with left-sided valvular heart disease.

Eur Heart J 2022 May;43(19):1792-1793

Department of Cardiovascular Science, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo A. Gemelli 8, Rome 00168, Italy.

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Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification.

JACC Basic Transl Sci 2022 Apr 23;7(4):333-345. Epub 2022 Mar 23.

Section of Cardiovascular Medicine and Cardiovascular Research Center, Yale University School of Medicine, New Haven, Connecticut, USA.

Expression of a neuropilin-like protein, DCBLD2, is reduced in human calcific aortic valve disease (CAVD). DCBLD2-deficient mice develop bicuspid aortic valve (BAV) and CAVD, which is more severe in BAV mice compared with tricuspid littermates. In vivo and in vitro studies link this observation to up-regulated bone morphogenic protein (BMP)2 expression in the presence of DCBLD2 down-regulation, and enhanced BMP2 signaling in BAV, indicating that a combination of genetics and BAV promotes aortic valve calcification and stenosis. Read More

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A Computational Framework for Atrioventricular Valve Modeling Using Open-Source Software.

J Biomech Eng 2022 Oct;144(10)

Department of Anesthesiology and Critical Care Medicine, Division of Pediatric Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA 19104.

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced substantially over the last decade and holds particular promise to inform valve repair in small and heterogeneous populations, which are less likely to be optimized through empiric clinical application. While an abundance of computational biomechanics studies has investigated mitral and tricuspid valve disease in adults, few studies have investigated its application to vulnerable pediatric and congenital heart populations. Read More

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October 2022

Approach to the Patient with a Murmur.

Med Clin North Am 2022 May 4;106(3):545-555. Epub 2022 Apr 4.

Department of Internal Medicine, UC Davis School of Medicine, 4150 V Street, Suite 2400, Sacramento, CA 95817, USA.

Patients with valvular heart disease may present with or without symptoms. A thorough cardiac physical examination can identify patients who require further evaluation and management. Although the utility of different cardiac findings varies widely, diastolic murmurs indicate important underlying valvular pathology requiring further investigation, typically with echocardiography. Read More

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Echocardiographic Indices in Pediatric Chronic Kidney Disease.

Iran J Kidney Dis 2022 03;16(2):88-95

Pediatric Cardiology Department, Mofid Children's Hospital, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Introduction: Cardiovascular disease (CVD) may accompany chronic kidney disease (CKD), resulting in additional complications and increased death rate. This study was performed to evaluate cardiac structure and function and several risk factors in hospitalized CKD children.

Methods: Seventy-four children with CKD were enrolled in this cross-sectional descriptive study. Read More

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[A Huge Aortic Root Aneurysm Nineteen Years After Aortic Valve Replacement:Report of a Case].

Kyobu Geka 2022 May;75(5):396-399

Department of Cardiovascular Surgery, Yokkaichi Municipal Hospital, Yokkaichi, Japan.

We report a case of huge aortic root aneurysm 19 years after aortic valve replacement. A 58-year-old woman was referred to us for aortic root dilatation. She underwent aortic valve replacement with mechanical valve due to severe aortic regurgitation of tricuspid aortic valve 19 years ago. Read More

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Incremental Prognosis by Left Atrial Functional Assessment: The Left Atrial Coupling Index in Patients With Floppy Mitral Valves.

J Am Heart Assoc 2022 May 26;11(9):e024814. Epub 2022 Apr 26.

Department of Cardiovascular Medicine Mayo Clinic Rochester MN.

Background Emerging data suggest important prognostic value to left atrial (LA) characteristics, but the independent impact of LA function on outcome remains unsubstantiated. Thus, we aimed to define the incremental prognostic value of LA coupling index (LACI), coupling volumetric and mechanical LA characteristics and calculated as the ratio of left atrial volume index to tissue Doppler imaging a', in a large cohort of patients with isolated floppy mitral valve. Methods and Results All consecutive 4792 patients (61±16 years, 48% women) with isolated floppy mitral valve in sinus rhythm diagnosed at Mayo Clinic from 2003 to 2011, comprehensively characterized and with prospectively measured left atrial volume index and tissue Doppler imaging a' in routine practice, were enrolled, and their long-term survival analyzed. Read More

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Surgical Correction of Carcinoid Heart Disease Improves Liver Function and 5-Hydroxyindoleacetic Acid Levels.

Front Surg 2022 8;9:791058. Epub 2022 Apr 8.

Department of Hepatology, Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

Introduction: Carcinoid heart disease (CHD) is a consequence of neuroendocrine tumors releasing 5-hydroxytryptamine (5-HT) into the systemic circulation, affecting right heart valves, causing fibrosis, and eventually right heart failure. The aim of this study was to determine the effect of valve-replacement on kidney function, liver function, and 5-hydroxyindoleacetic acid (5-HIAA) levels.

Methods: A Retrospective study of 17 patients with CHD who had undergone heart-valve replacement surgery between 2010 and 2019, from the Queen Elizabeth Hospital Birmingham. Read More

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Pre-operative 2-D transthoracic echocardiographic diagnosis with intra-operative findings of children with structural heart diseases: A comparative analysis.

Niger J Clin Pract 2022 Apr;25(4):478-482

Department of Paediatrics/Paediatric Cardiology Unit, University of Nigeria, Ituku Ozalla, Enugu, Nigeria.

Background: Structural heart disease is a major cause of morbidity and mortality in children. Echocardiography is accepted as the first line cost-effective diagnostic modality for pre-operative assessment of children with structural heart diseases. Two-dimensional transthoracic echocardiography (2-D TTE) may be the only diagnostic tool in a resource-poor environment where further investigations may be very expensive and not readily available. Read More

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Metastatic osteosarcoma tumor thrombus in a Cavalier King Charles Spaniel presenting with dyspnea.

J Vet Cardiol 2022 Mar 23;41:209-215. Epub 2022 Mar 23.

Langford Vets, University of Bristol, Stock Lane, Lower Langford, North Somerset, BS40 5DU, United Kingdom; Highcroft Veterinary Referrals, 615 Wells Road, Whitchurch, Bristol, Avon, BS14 9BE, United Kingdom. Electronic address:

A six-year-seven-month-old female neutered Cavalier King Charles Spaniel was referred for the investigation of progressive dyspnea and hyphema in the right eye with secondary glaucoma. Previous medical history included a high-grade soft tissue spindle cell sarcoma removed from the cranial sternal region one year before. On presentation at the referral hospital, the dog was tachypneic and dyspneic. Read More

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Tricuspid atresia with absent pulmonary valve: A rare form of single ventricle.

J Card Surg 2022 Jul 17;37(7):1854-1860. Epub 2022 Apr 17.

Department of Cardiothoracic Surgery, Division of Congenital Cardiothoracic Surgery, Hassenfeld Children's Hospital, New York University, New York, New York, USA.

Tricuspid atresia with an absent pulmonary valve is a rare congenital cardiac defect. Although extensive pathological reviews have been published in the past, there are only a handful of cases that have been successfully palliated to the stage of Fontan. We hereby describe the successful management of one such case and review the surgical strategies described in the literature. Read More

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Paravalvular Leak.

Methodist Debakey Cardiovasc J 2022 1;18(1):7-9. Epub 2022 Apr 1.

Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas, US.

Despite improvements and advancements in surgical technique, paravalvular leaks (PVL) continue to present a challenge when caring for patients with prosthetic valve disease. Paravalvular leaks result from dehiscence of the surgical ring from the mitral annulus. Some theories suggest that uneven distribution of collagen fibers in the mitral annulus leaves the posterior mitral annulus without a well-formed fibrous structure, which may predispose it to recurrent mechanical injury that leads to PVL. Read More

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Heritability of aortic valve stenosis and bicuspid enrichment in families with aortic valve stenosis.

Int J Cardiol 2022 Jul 13;359:91-98. Epub 2022 Apr 13.

l'institut du thorax, INSERM, CNRS, UNIV Nantes, Nantes, France.. Electronic address:

Background: Although a familial component of calcific aortic valve stenosis (CAVS) has been described, its heritability remains unknown. Hence, we aim to assess the heritability of CAVS and the prevalence of bicuspid aortic valve among CAVS families.

Methods: Probands were recruited following aortic valve replacement (AVR) for severe CAVS on either tricuspid (TAV) or bicuspid aortic valve (BAV). Read More

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Prevalence and Outcomes of Bicuspid Aortic Valve in Patients With Aneurysmal Sub-Arachnoid Hemorrhage: A Prospective Neurology Registry Report.

J Am Heart Assoc 2022 04 12;11(8):e022339. Epub 2022 Apr 12.

Department of Cardiovascular Medicine Mayo Clinic Rochester MN.

Background Intracranial aneurysms are reported in 6%-10% of patients with bicuspid aortic valve (BAV), and routine intracranial aneurysm surveillance has been advocated by some. We assessed the prevalence and features of the most important patient-outcome: aneurysmal sub-arachnoid hemorrhage (aSAH), as compared with controls without aSAH, and tricuspid aortic valve (TAV) with aSAH. Methods and Results Adult patients with accurate diagnosis of aSAH and at least one echocardiogram between 2000 and 2019 were identified from a consecutive prospectively maintained registry of aSAH admissions. Read More

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Risk of Coronary Obstruction During Redo-TAVR in Patients With Bicuspid Versus Tricuspid Aortic Valve Stenosis.

JACC Cardiovasc Interv 2022 04;15(7):712-724

Department of Cardiology, West China Hospital, Sichuan University, Chengdu, China. Electronic address:

Objectives: The aim of this study was to investigate the risk of coronary obstruction during redo-transcatheter aortic valve replacement (TAVR) within a previously implanted self-expanding valve in bicuspid aortic valve (BAV) versus tricuspid aortic valve (TAV) stenosis.

Background: The prevalence of BAV in TAVR patients is expected to increase as the indication expands; however, no study has investigated the risk of coronary obstruction for future redo-TAVR in these patients.

Methods: Computed tomography (CT) simulation analysis was performed in 86 type 0 BAV, 70 type 1 BAV, and 132 TAV patients who underwent TAVR with 1 VenusA-Valve (Venus Medtech) between January 2014 and December 2019. Read More

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Impact of serial measurements of tricuspid annular plane systolic excursion on mortality and morbidity after heart transplantation.

Clin Transplant 2022 Jun 26;36(6):e14662. Epub 2022 Apr 26.

Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.

The impact of right ventricular (RV) dysfunction on long-term post-HTx outcomes remains uncertain. We assessed the impact of serial measurements of Tricuspid Annular Plane Systolic Excursion (TAPSE) on post-HTx mortality and morbidity. This two-center retrospective cohort study included consecutive adult HTx recipients (2000-2017). Read More

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Cor triatriatum dexter of unusual morphology in a miniature schnauzer.

J Vet Cardiol 2022 Mar 4;41:165-171. Epub 2022 Mar 4.

Department of Small Animal Clinical Science, School of Veterinary Science, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, CH64 7TE, UK.

A five-year-nine-month-old, male entire, miniature schnauzer presented for further investigation of pleural effusion. Echocardiography revealed a perforated membrane dividing the right atrium into two chambers: the true right atrium (a small, lower-pressure, cranioventral chamber communicating with the tricuspid valve and right ventricle) and the accessory right atrium (a larger, higher-pressure, caudodorsal chamber), consistent with a cor triatriatum dexter. This was confirmed using computed tomography angiography. Read More

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Rotation characteristics and neo-commissural alignment of transcatheter heart valve in type-0 bicuspid aortic valve.

J Card Surg 2022 Jun 29;37(6):1486-1496. Epub 2022 Mar 29.

Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Aims: This study sought to characterize the rotation of the transcatheter heart valve (THV) and evaluate the neo-commissures overlap with coronary arteries in type-0 bicuspid aortic valve (BAV).

Methods And Results: This was a single-center, 10-patient, retrospective observational cohort. Pre-TAVI computed tomography and procedural fluoroscopy were analyzed. Read More

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Elevated tricuspid regurgitation velocity is associated with increased adverse haematologic events during pregnancy in women with sickle cell disease.

Br J Haematol 2022 Jun 24;197(6):795-801. Epub 2022 Mar 24.

Department of Internal Medicine, Division of Cardiovascular Medicine, The Ohio State University & Nationwide Children's Hospital, Columbus, Ohio, USA.

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Abnormal wire's trajectory during edge-to-edge mitral valve repair-a rare case report of inferior vena cava anomaly.

Eur Heart J Case Rep 2022 Feb 7;6(2):ytac060. Epub 2022 Feb 7.

Smidt Heart Institute, Cedars-Sinai Medical Center, 127 S. San Vicente Boulevard, Advanced Health Sciences Pavilion, Third Floor, Suite A3100, Los Angeles, CA 90048, USA.

Background: Inferior vena cava (IVC) anomalies are rare and diagnosed incidentally as most patients are asymptomatic. We present a case where an abnormal course of the wire during percutaneous mitral valve repair revealed abnormal IVC anatomy leading to procedure termination. We summarized all IVC anomalies relevant to cardiovascular physicians and designed a simplified tool to illustrate their course for differential diagnosis. Read More

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February 2022