23,857 results match your criteria Tricuspid Atresia


Pulmonary embolectomy in a case of subacute pulmonary embolism, with previous unsuccessful fibrinolysis

Rev Med Inst Mex Seguro Soc 2018 11 30;56(4):418-423. Epub 2018 Nov 30.

Universidad Nacional Autónoma de México, Facultad de Medicina, División de Estudios de Posgrado. Ciudad de México, México

Background: Pulmonary embolism is a potentially fatal heart condition that requires prompt restoration of blood flow in the pulmonary vascular bed and prevention of recurrent events. Mortality is associated to the degree of hemodynamic repercussion, complications and opportunity in the treatment.

Case Report: Male 33 years of age who began with sudden dyspnea, chest pain of moderate intensity, sweating and syncope. Read More

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November 2018

Value of tissue-tracking tricuspid annular plane by speckle-tracking echocardiography for the assessment of right ventricular systolic dysfunction.

Echocardiography 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.

Background: Assessment of right ventricular (RV) function remains challenging because of its complex geometry. Application of speckle-tracking echocardiography (STE) to the tricuspid annulus provides rapid and automated assessment of the midpoint of the tricuspid annular plane displacement (TAD). The aim of this study was to investigate the value of tissue-tracking TAD for the assessment of RV systolic dysfunction. Read More

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December 2018

Characteristics, Mechanism and Long-Term Ablation Outcome of Atrial Tachycardias After Mitral Valvular Surgery and Concomitant Cox-MAZE IV Procedure.

Int Heart J 2018 Dec 5. Epub 2018 Dec 5.

Department of Cardiology, Atrial Fibrillation Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences.

The incidence of atrial tachycardia (AT) after rheumatic mitral valvular (RMV) surgery has been well described. However, there have been few reports on the characteristics, mechanism, and long-term ablation outcome of ATs after RMV surgery and concomitant Cox-MAZE IV procedure.The present study reviewed consecutive patients who underwent AT ablation between May 2008 and July 2013. Read More

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December 2018

Natural history of bivalvular functional regurgitation.

Eur Heart J Cardiovasc Imaging 2018 Dec 1. Epub 2018 Dec 1.

Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

Aims: Bivalvular functional regurgitation (BVFR) defined as concomitant mitral and tricuspid insufficiency has not been described or systematically assessed before. Therefore, this study sought to define incidence, impact and natural history of BVFR in heart failure with reduced ejection fraction (HFrEF) to provide the foundation for risk assessment and directions for potential treatment strategies.

Methods And Results: We enrolled 1021 consecutive patients with HFrEF under guideline-directed medical therapy and performed comprehensive echocardiographic and neurohumoral profiling. Read More

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December 2018

Altered biventricular hemodynamic forces in patients with repaired tetralogy of Fallot and right ventricular volume overload because of pulmonary regurgitation.

Am J Physiol Heart Circ Physiol 2018 Dec 28;315(6):H1691-H1702. Epub 2018 Sep 28.

Lund University, Department of Clinical Sciences, Lund, Clinical Physiology, Skåne University Hospital , Sweden.

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed to quantify the hemodynamic forces in patients with repaired tetralogy of Fallot (rToF) to further understand the pathophysiological mechanisms as this could be a potential marker for pulmonary valve replacement (PVR) in these patients. Patients with rToF and pulmonary regurgitation (PR) > 20% ( n = 18) and healthy control subjects ( n = 15) underwent MRI, including four-dimensional flow. Read More

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December 2018

A Pathogenic Homozygous Mutation in The Pleckstrin Homology Domain of RASA1 Is Responsible for Familial Tricuspid Atresia in An Iranian Consanguineous Family.

Cell J 2019 Apr 18;21(1):70-77. Epub 2018 Nov 18.

Department of Pediatrics Cardiology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic Address:

Objective: Tricuspid atresia (TA) is a rare life-threatening form of congenital heart defect (CHD). The genetic mechanisms underlying TA are not clearly understood. According to previous studies, the endocardial cushioning event, as the primary sign of cardiac valvulogenesis, is governed by several overlapping signaling pathways including Ras/ ERK pathway. Read More

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Snow and Reindeer: Large Tricuspid Valve Mobile Vegetation.

J Invasive Cardiol 2018 Dec;30(12):E155

Staten Island University Hospital-Northwell Health, 475 Seaview Avenue, Staten Island, NY 10305 USA.

A 20-year-old female with history of polysubstance abuse presented with fevers and lightheadness. Blood cultures grew out Streptococcus constellatus, which is known to form purulent infections when introduced in the body. Evaluation with transesophageal echocardiogram showed a definite large, irregular, loosely organized, highly mobile vegetation. Read More

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December 2018

Surgical treatment of right-sided infective endocarditis.

J Thorac Cardiovasc Surg 2018 Sep 25. Epub 2018 Sep 25.

Heart and Vascular Institute, Department of Thoracic and Cardiovascular Surgery. Electronic address:

Objective: Right-sided infective endocarditis is increasing because of increasing prevalence of predisposing conditions, and the role and outcomes of surgery are unclear. We therefore investigated the surgical outcomes for right-sided infective endocarditis.

Methods: From January 2002 to January 2015, 134 adults underwent surgery for right-sided infective endocarditis. Read More

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September 2018

Transcatheter Tricuspid Valve Repair With a Novel Cinching System.

JACC Cardiovasc Interv 2018 Nov 23. Epub 2018 Nov 23.

Interventional Cardiology Unit, AZ Sint-Jan Hospital, Brugge, Belgium. Electronic address:

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November 2018

Multiplane Intracardiac Echocardiography: A Novel System to Guide Percutaneous Tricuspid Repair.

JACC Cardiovasc Interv 2018 Nov 23. Epub 2018 Nov 23.

Heart and Vascular Center, University of Virginia, Charlottesville, Virginia; Advanced Cardiac Valve Center, University of Virginia, Charlottesville, Virginia.

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November 2018

Mid-term results of a randomized trial of tricuspid annuloplasty for less-than-severe functional tricuspid regurgitation at the time of mitral valve surgery†.

Eur J Cardiothorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Cardiac Surgery Department, Universitair Clinique St. Luc, Brussel, Belgium.

Objectives: The optimal management of functional tricuspid regurgitation (FTR) in the setting of mitral valve operations remains controversial. The current practice is both centre specific and surgeon specific with guidelines based on non-randomized data. A prospective randomized trial was performed to evaluate the worth of less-than-severe FTR repair during mitral valve procedures. Read More

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December 2018
1 Read

Male-female differences in characteristics and early outcomes of patients undergoing tricuspid valve surgery: a national cohort study in the Netherlands.

Eur J Cardiothorac Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Cardiothoracic Surgery, Erasmus MC, Rotterdam, Netherlands.

Objectives: This study aims to explore male-female differences in baseline and procedural characteristics, and outcomes of patients undergoing isolated or concomitant tricuspid valve (TV) surgery.

Methods: All TV procedures registered between 2007 and 2016 in the database of the Netherlands Association for Cardio-Thoracic Surgery were analysed. Logistic regression analyses with interaction terms were used to determine whether sex was associated with hospital mortality. Read More

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December 2018

Transcatheter Closure of Perimembranous Ventricular Septal Defects in Children using a Wire-Drifting Technique.

Clinics (Sao Paulo) 2018 Nov 29;73:e371. Epub 2018 Nov 29.

Department of Structural Heart Disease, The First Affiliated Hospital of Xi'an Jiaotong University, Shaanxi Province, China.

Objective: Explore the feasibility and safety of transcatheter closure of perimembranous ventricular septal defects using a wire-drifting technique (WT) in children.

Methods: We retrospectively analyzed 121 pediatric patients diagnosed with perimembranous ventricular septal defects who underwent interventional treatment at the First Affiliated Hospital of Xi'an Jiaotong University from Dec 2011 to Dec 2014. Based on the method used for arteriovenous loop establishment during the procedure, the patients were divided into a conventional technique (CT) group and a WT group. Read More

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November 2018

Primary Cardiac Angiosarcoma with Rare Presenting Feature and Successful Surgical Treatment.

Braz J Cardiovasc Surg 2018 Sep-Oct;33(5):525-527

Department of Cardiovascular Surgery, Kartal Kosuyolu Heart Research and Training Hospital, Istanbul, Turkey.

Primary angiosarcoma is a rare clinical entity, it's typically located within the right atrium and known to be rapidly fatal. A 37-year-old female was presented with a history of recurrent facial paralysis and left hemiparesis. A cranial mass was identified at cranial magnetic resonance imaging and she underwent neurosurgery operation. Read More

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December 2017
1 Read

Assessment of right ventricular systolic function in children with repaired tetralogy of fallot by multiple-view from single acoustic window with speckle tracking echocardiography.

Echocardiography 2018 Dec 4. Epub 2018 Dec 4.

Department of Pediatric Cardiology, Shanghai Children's Medical Center, Shanghai Jiao-Tong University School of Medicine, Shanghai, China.

Background: Challenges remain in quantitative evaluation of right ventricular (RV) function by echocardiography. Multiple-view assessment is believed to provide a more comprehensive quantification of RV function than conventional single-view analysis. Peak systolic longitudinal RV strain (RVLS) measured by speckle tracking echocardiography (STE) has clinical and prognostic value. Read More

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December 2018
1 Read

Impact of Tricuspid Regurgitation and Right Ventricular Dysfunction on Outcomes After Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-Analysis.

Clin Cardiol 2018 Dec 4. Epub 2018 Dec 4.

Zhejiang University School of Medicine, Hangzhou, People's Republic of China.

Background: Far less attention has been paid to the prognostic effect of right-side heart disease on outcomes after transcatheter aortic valve replacement (TAVR) when compared with the left side. Therefore, we performed a systematic review and meta-analysis on the impact of tricuspid regurgitation (TR) and right ventricular (RV) dysfunction on outcomes after TAVR.

Hypothesis: We hypothesized that TR and RV dysfunction may have a deleterious effect on outcomes after TAVR. Read More

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December 2018

An investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets.

J Biomech 2018 Nov 16. Epub 2018 Nov 16.

Biomechanics and Biomaterials Design Laboratory (BBDL), School of Aerospace and Mechanical Engineering, The University of Oklahoma, Norman, OK 73019, USA; Institute for Biomedical Engineering, Science and Technology, The University of Oklahoma, Norman, OK 73019, USA. Electronic address:

The facilitation of proper blood flow through the heart depends on proper function of heart valve components, and alterations to any component can lead to heart disease or failure. Comprehension of these valvular diseases is reliant on thorough characterization of healthy heart valve structures for use in computational models. Previously, computational models have treated these leaflet structures as a structurally and mechanically homogenous material, which may not be an accurate description of leaflet mechanical response. Read More

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November 2018

[Surgical management of atrioventricular valve regurgitation in functional single ventricle].

Zhonghua Wai Ke Za Zhi 2018 Dec;56(12):922-927

Department of Cardiac Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China.

To evaluate the early- and mid-term outcomes of surgical atrioventricular valve (AVV) intervention in patients with functional single ventricle (FSV). The clinical data of 40 consecutive FSV patients who underwent surgical AVV intervention between January 2008 and December 2017 at Department of Cardiac Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University were reviewed retrospectively. There were 25 male and 15 female patients. Read More

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December 2018

An atypical case of pulmonary embolism from a jugular vein.

Echo Res Pract 2018 Dec;5(4):K67-K72

University of Medicine and Pharmacy, Carol Davila, Bucharest, Romania.

Neck venous malformations and their potentially life-threatening complications are rarely reported in the available literature. Cases of aneurysmal or hypo-plastic jugular vein thrombosis associated with systemic embolization have not been frequently reported. We present the case of a 60-year-old male, without any known risk factors for thromboembolic disease, admitted for sudden onset dyspnea. Read More

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December 2018
5 Reads

Embolization of Endocardial Vegetation With Stroke Presentation.

Am J Forensic Med Pathol 2018 Nov 27. Epub 2018 Nov 27.

Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC.

This case report details the unique cause of death of a 37-year-old Caucasian woman with a history significant for intravenous drug abuse. Before her death, she complained of extremity weakness and pain. Although her death was discovered to be the result of endocarditis, her symptoms were similar to that of a stroke. Read More

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November 2018
3 Reads

Atrial Tachycardia with Fibrillatory Activity in the Superior Vena Cava.

J Cardiovasc Electrophysiol 2018 Nov 29. Epub 2018 Nov 29.

Department of Cardiology, The Jikei University of Medicine, Tokyo, Japan.

A 59-year-old man who had undergone catheter ablations for paroxysmal atrial fibrillation (AF) twice was referred for a third procedure due to atrial tachycardia (AT) recurrence. In addition to pulmonary vein (PV) isolation, linear ablation (roof/mitral isthmus lines), cavo-tricuspid isthmus ablation and superior vena cava (SVC) isolation had been conducted in the previous procedures. The intracardiac electrograms showed AT with irregular cycle length, and a circular mapping catheter obliquely placed in the SVC showed both fibrillatory activation and organized activation simultaneously. Read More

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November 2018
3 Reads

Aortic stiffness in aortic stenosis assessed by cardiovascular MRI: a comparison between bicuspid and tricuspid valves.

Eur Radiol 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiovascular Sciences, University of Leicester and Cardiovascular Theme, NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Groby road, Leicester, LE3 9QP, UK.

Objectives: To compare aortic size and stiffness parameters on MRI between bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) patients with aortic stenosis (AS).

Methods: MRI was performed in 174 patients with asymptomatic moderate-severe AS (mean AVAI 0.57 ± 0. Read More

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November 2018

Early and Late Outcomes of Isolated Tricuspid Valve Surgery Following Valvular Surgery.

Ann Thorac Cardiovasc Surg 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital, Kobe, Hyogo, Japan.

Purpose: Isolated tricuspid valve surgery (TVS) following valvular surgery has been still challenging. We reviewed our experience to determine early and late outcomes.

Methods: We retrospectively analyzed 14 patients (mean age, 57. Read More

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November 2018

The relationship between serum apelin levels and aortic dilatation in bicuspid aortic valve patients.

Congenit Heart Dis 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiology, Katip Çelebi University Atatürk Training and Research Hospital, Izmir, Turkey.

Objective: The bicuspid aortic valve (BAV) is the most common congenital heart disease. The process of aortic dilatation is not completely clear in patients with the BAV. Apelin is a peptide found at high levels in vascular endothelial cells which has a role in vascular regulation and cardiovascular function. Read More

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November 2018
2 Reads

Peak systolic velocity of tricuspid annulus is inferior to tricuspid annular plane systolic excursion for 30 days prediction of adverse outcome in acute pulmonary embolism.

Cardiol J 2018 Nov 28. Epub 2018 Nov 28.

Department of Internal Medicine and Cardiology, Medical University of Warsaw, Warsaw Lindleya str 4, 02-005 Warsaw, Poland.

Background: Tricuspid annular plane systolic excursion (TAPSE) is an established index of right ventricular (RV) systolic function and a significant predictor in normotensive patients with pulmonary embolism (PE). Recently, Doppler tissue imaging-derived tricuspid annular systolic velocity (TV S'), a modern parameter of RV function was reported to be useful in the diagnosis and prognosis of a broad spectrum of heart diseases. Therefore, herein, is an analysis of the prognostic value of both parameters in normotensive PE patients. Read More

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November 2018

High tumour burden, delayed diagnosis and history of cardiovascular disease may be associated with carcinoid heart disease.

Ecancermedicalscience 2018 25;12:879. Epub 2018 Oct 25.

Instituto do Câncer do Estado de São Paulo, University of São Paulo, São Paulo, Brazil.

Background: Patients with carcinoid syndrome (CS) may present carcinoid heart disease (CHD) but prognostic factors are not entirely understood.

Patients And Methods: Retrospective study of patients with metastatic neuroendocrine tumours (NETs) and CS and/or abnormal 24-hour-urinary 5-hydroxiindolacetic acid. CHD was defined as moderate to severe tricuspid or pulmonary regurgitation in the echocardiogram. Read More

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October 2018

Right ventricular load adaptability metrics in patients undergoing left ventricular assist device implantation.

J Thorac Cardiovasc Surg 2018 Sep 25. Epub 2018 Sep 25.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, Calif.

Objective: Several right load adaptability metrics have been proposed as predictors of right heart failure (RHF) following left ventricular assist device implantation. This study sought to validate and compare the prognostic value of these indices.

Methods: This retrospective study included 194 patients undergoing continuous-flow left ventricular assist device implantation. Read More

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September 2018

Noninvasive mapping before surgical ablation for persistent, long-standing atrial fibrillation.

J Thorac Cardiovasc Surg 2018 Sep 25. Epub 2018 Sep 25.

Washington Adventist Hospital, Takoma Park, Md; West Virginia University, Morgantown, WVa.

Objective: The study objective was to study the electrophysiologic mechanism of atrial fibrillation using a noninvasive, beat-by-beat, 3-dimensional mapping technique in patients with persistent and long-standing persistent atrial fibrillation undergoing concomitant surgical ablation.

Methods: In this pilot trial, 10 patients (6 male; mean age, 70 ± 10 years) with persistent atrial fibrillation were mapped preoperatively with a noninvasive surface system (ECVUE, CardioInsight, Medtronic Inc, Minneapolis, Minn). Eight patients were candidates for mitral valve surgery, 1 patient was a candidate for aortic valve and ascending aortic replacement, and 1 patient was a candidate for coronary bypass surgery. Read More

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September 2018
2 Reads

Novel transcatheter therapies for treating tricuspid regurgitation.

Minerva Cardioangiol 2018 Nov 26. Epub 2018 Nov 26.

Heart Valve Clinic, University Hospital of Zurich, Zurich, Switzerland -

Until recently, tricuspid valve (TV) disease has been relatively neglected for a long time, but recently tricuspid regurgitation (TR) has attracted attention. Although the prognosis of patients with these disorders is poor, the high mortality and morbidity associated with TV surgery have resulted in many patients not receiving surgical therapy. Current guidelines recommend that TV surgery should be considered in patients with severe TR who are symptomatic or have progressive right ventricle (RV) dilatation or dysfunction. Read More

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November 2018
3 Reads

Impact of concurrent tricuspid regurgitation on mortality after transcatheter aortic-valve implantation.

Catheter Cardiovasc Interv 2018 Nov 25. Epub 2018 Nov 25.

Department of Cardiology, Detroit Medical Center, Detroit, Michigan.

Objectives: To determine whether concomitant tricuspid regurgitation (TR) is associated with increased mortality in patients with severe aortic stenosis (AS) undergoing transcatheter aortic-valve implantation (TAVI), we performed a meta-analysis of currently available studies.

Methods: MEDLINE and EMBASE were searched through May 2018. We included comparative or cohort studies enrolling patients with AS undergoing TAVI and reporting early (in-hospital or 30-day) and late (including early) all-cause mortality in patients stratified by baseline TR grade. Read More

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November 2018
1 Read

The Conundrum of Tricuspid Regurgitation Grading.

Front Cardiovasc Med 2018 9;5:164. Epub 2018 Nov 9.

Department of Cardiology, University Hospital Sart Tilman, Heart Valve Clinic, University of Liège, Liège, Belgium.

Findings from early percutaneous tricuspid intervention trials have shown that the severity of tricuspid regurgitation (TR) far exceeded the current definition of severe TR. Also, the improvement in the amount of TR following tricuspid intervention is not accounted for by the current definition of TR as different degrees of severity at the severe end was grouped under the same umbrella term of "severe." There has been a recent call to expand the TR grading system, encompassing two more grades, namely "massive" and "torrential" TR, in the order of increasing severity. Read More

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November 2018
8 Reads

Right ventricular and pulmonary vascular function are influenced by age and volume expansion in healthy humans.

J Card Fail 2018 Nov 22. Epub 2018 Nov 22.

Dept. of Cardiology, Odense University Hospital, Odense, Denmark.

Background: Patients with heart failure (HF) often show signs of RV dysfunction. The function of RV coupled with the pulmonary circulation (tricuspid annular plane systolic excursion [TAPSE]: pulmonary artery systolic pressure [PASP]) has been shown to divide HF patients into distinct prognostic strata, however less is known about which factors influence this prognostic marker, and whether these factors can be modified. We sought to obtain normative values and discern the individual effects of age, gender, and fluid overload on right ventricular (RV) function. Read More

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November 2018
2 Reads

What echocardiographic findings suggest a pericardial effusion is causing tamponade?

Am J Emerg Med 2018 Nov 17. Epub 2018 Nov 17.

Department of Emergency Medicine, Rutgers New Jersey Medical School, 150 Bergen Street, Newark, NJ 07103, USA.

Background: Pericardial tamponade is neither a clinical nor an echocardiographic diagnosis alone. The echocardiogram carries diagnostic value and should be performed when there is suspicion for tamponade based on the history and physical exam. A pericardial effusion uncovered on point-of-care ultrasound (POCUS) may be mistaken for tamponade and thereby lead to inappropriate and invasive management with pericardiocentesis. Read More

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November 2018
4 Reads

Assessment of lateral mitral, septal and tricuspid myocardial performance indices by tissue Doppler imaging in asthmatic children.

Clin Respir J 2018 Nov 24. Epub 2018 Nov 24.

Masters pediatrics, Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Introduction: Recurrent hypoxia makes asthmatics at risk for pulmonary hypertension and ventricular dysfunction. Early stages of these cardiovascular diseases cannot be detected by conventional echocardiography. Tissue Doppler imaging has been introduced recently as a more sensitive & more accurate tool for investigating cardiovascular diseases. Read More

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November 2018
3 Reads

Echocardiographic evaluation of prevalence of pulmonary hypertension in β-thalassemia major: A cross sectional study.

Pediatr Hematol Oncol 2018 Nov 23:1-9. Epub 2018 Nov 23.

c Oncology Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.

Introduction: Pulmonary hypertension is a common complication associated with thalassemia syndromes and it may play an important role in the pathogenesis of right ventricle failure. The true prevalence of pulmonary hypertension in patients with thalassemia major remains unclear and has been reported to be between 2 and 79%.

Materials And Methods: In total, 70 patients with thalassemia major were initially examined. Read More

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November 2018
2 Reads

Tricuspid regurgitation: from physiopathology to transcatheter interventions.

Minerva Cardioangiol 2018 Dec;66(6):671-672

Unit of Cardiovascular Interventions, Humanitas Research Hospital, Rozzano, Milan, Italy -

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December 2018
1 Read

Evaluation of Electrophysiological Mechanisms of Post-Surgical Atrial Tachycardias Using an Automated Ultra-High-Density Mapping System.

JACC Clin Electrophysiol 2018 Nov 29;4(11):1460-1470. Epub 2018 Aug 29.

Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China; Guangdong Provincial Key Laboratory of Clinical Pharmacology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China. Electronic address:

Objectives: This study aimed to evaluate the electrophysiological mechanisms of post-surgical atrial tachycardias (ATs) during mapping with an automated high-resolution mapping system (Rhythmia, Boston Scientific, Marlborough, Massachusetts).

Background: Mapping and ablation of post-operative ATs following previous open-heart surgery is often challenging because the potential mechanisms remain incompletely understood.

Methods: Fifty-one consecutive patients underwent mapping and ablation of post-surgical ATs. Read More

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November 2018
3 Reads

Transvenous Extraction of Pacemaker and Defibrillator Leads and the Risk of Tricuspid Valve Regurgitation: Making a Case for Thoughtful Lead Management.

JACC Clin Electrophysiol 2018 Nov;4(11):1429-1430

Division of Cardiology, University of California-San Diego, La Jolla, California.

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November 2018
2 Reads

Transvenous Extraction of Pacemaker and Defibrillator Leads and the Risk of Tricuspid Valve Regurgitation.

JACC Clin Electrophysiol 2018 Nov 26;4(11):1421-1428. Epub 2018 Sep 26.

Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio. Electronic address:

Objectives: The aims of this study were to detect and quantify acute increases in tricuspid regurgitation (TR) severity following transvenous lead extraction (TLE) and to evaluate the associated risk factors.

Background: Although established as a safe and effective method for lead removal, TLE is sometimes complicated by TR.

Methods: In 208 consecutive patients undergoing TLE, acute changes in TR severity were assessed by transesophageal echocardiography. Read More

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November 2018
5 Reads

Left ventricular diastolic function influences right ventricular - Pulmonary vascular coupling in premature infants.

Early Hum Dev 2018 Nov 19;128:35-40. Epub 2018 Nov 19.

Department of Pediatrics, Washington University School of Medicine, Saint Louis, MO, USA; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA. Electronic address:

Introduction: Reduced left ventricular (LV) diastolic function can exert significant load to the right ventricle (RV) that can affect RV-pulmonary vasculature (PV) coupling. RV-PV can be assessed with the RV length-force relationship (tricuspid annular plane systolic excursion [TAPSE] to pulmonary artery acceleration time [PAAT] ratio). We aimed to determine the association between LV diastolic function measured using tissue Doppler imaging (TDI) and TAPSE/PAAT. Read More

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November 2018

Comparison Of The Efficacy Of Sildenafil Alone Versus Sildenafil Plus Bosentan In Newborns With Persistent Pulmonary Hypertension.

J Ayub Med Coll Abbottabad 2018 Jul-Sep;30(3):333-336

Forensic Medicine Ayub Medical College, Abbottabad, Pakistan.

Background: Persistent pulmonary hypertension is a serious disease among new-borns. Inhaled nitric oxide is first line of therapy along with extracorporeal membrane oxygenation. Pulmonary vasodilators such as sildenafil, bosentan and milrinone are also used to treat persistent pulmonary hypertension especially in resource limited centres where inhaled nitric oxide is not available. Read More

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November 2018
1 Read

Atrial Fibrillation Predicts Long-Term Outcome after Transcatheter Edge-to-Edge Mitral Valve Repair by MitraClip Implantation.

Biomolecules 2018 Nov 19;8(4). Epub 2018 Nov 19.

Department of Internal Medicine II, University of Ulm, 89081 Ulm, Germany.

: Atrial fibrillation is common in patients with mitral regurgitation (MR) and has a negative impact on the clinical outcome of patients with valvular heart disease. We aimed to evaluate the impact of pre-procedural atrial fibrillation on the long-term clinical outcomes of patients with MR undergoing transcatheter mitral valve repair by MitraClip implantation. : We analysed 355 consecutive patients with and without atrial fibrillation with symptomatic, severe MR and inoperability or high surgical risk undergoing MitraClip implantation in a three-year follow-up. Read More

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November 2018
1 Read

Infertility in a man with oligoasthenozoospermia associated with mosaic chromosome 22q11 deletion.

Mol Genet Genomic Med 2018 Nov 20. Epub 2018 Nov 20.

SCU-CUHK Joint Laboratory for Reproductive Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, China.

Background: A 30-year-old oligoasthenozoospermia man was found to have unbalance mosaic translocation between chromosome 22 and four other chromosomes (5, 6, 13, and 15) during the investigations for a couple with infertility for 3 years, which is a rare event in human pathology.

Methods: Classical cytogenetics analysis, fluorescence in situ hybridization (FISH), and chromosome microarray analyses (CMA) were performed on peripheral blood lymphocytes; copy number variation sequencing (CNV-Seq) analysis was performed on sperm DNA.

Results: Classical cytogenetics analysis showed the presence of six cell lines on peripheral blood lymphocytes: 45, XY, der (13) t(13;22),-22[10]/46, XY, t(13;22)[6]/45, XY, der(15)t(15;22),-22[4]/46, XY, t(13;22)[1]/45, XY, der(5)t(5;22),-22[1]/45, XY, der(6)t(6;22)[1]. Read More

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November 2018
5 Reads

Insight on patient specific computer modeling of transcatheter aortic valve implantation in patients with bicuspid aortic valve disease.

Catheter Cardiovasc Interv 2018 Nov 20. Epub 2018 Nov 20.

St Antonius Hospital, Nieuwegein, The Netherlands.

Objective: The aim of this study was to describe the early use of dedicated patient specific computer modeling in patients with bicuspid aortic valve (BAV) undergoing transcatheter aortic valve implantation (TAVI), in predicting procedure feasibility and patient related outcome.

Background: Dedicated patient specific computer modeling, used for optimizing TAVI procedures, is currently validated for the prediction of contact pressure, valve morphology and paravalvular leakage (PVL). The simulation of TAVI procedures is increasingly used in patients with tricuspid aortic valve stenosis. Read More

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November 2018
2 Reads

Optimal exposure for closure of ventricular septal defects through the tricuspid valve.

Transl Pediatr 2018 Oct;7(4):367-368

Division of Pediatric and Congenital Heart Surgery, Children's Memorial Hermann Hospital, Houston, TX, USA.

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October 2018

Echocardiographic Assessment of the Tricuspid Annulus: The Effects of the Third Dimension and Measurement Methodology.

J Am Soc Echocardiogr 2018 Nov 17. Epub 2018 Nov 17.

Cardiac Imaging Center, University of Chicago Medical Center, Chicago, Illinois.

Background: Evaluation of the tricuspid annulus is crucial for the decision making at the time of left heart surgery. Current recommendations for tricuspid valve repair are based on two-dimensional (2D) transthoracic echocardiography (TTE), despite the known underestimation compared with three-dimensional (3D) echocardiography. However, little is known about the differences in 3D tricuspid annular (TA) sizing using TTE versus transesophageal echocardiography (TEE). Read More

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November 2018
2 Reads

Prognostic Value of Atrial Fibrillation Inducibility in Patients Without History of Clinical Atrial Fibrillation.

J Atr Fibrillation 2018 Jun-Jul;11(1):1837. Epub 2018 Jun 30.

Department of Cardiology and Cardiovascular Diseases, Eberhard Karls University, Tübingen, Germany.

Purpose: During invasive electrophysiological studies (EPS), atrial fibrillation (AF) can be induced in patients without a history of AF. However, the prognostic value is not well evaluated in this population. Our aim was to investigate whether AF inducibility in those patients is associated with future clinical episodes of AF; whether non-inducibility is predictive of freedom from new-onset AF and finally, to examine clinical factors associated with inducibility. Read More

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June 2018
5 Reads

Coronary Sinus Electrograms May Predict New-onset Atrial Fibrillation After Typical Atrial Flutter Radiofrequency Ablation (CSE-AF).

J Atr Fibrillation 2018 Jun-Jul;11(1):1809. Epub 2018 Jun 30.

Division of Cardiology, Heart Rhythm Service, Queen's University, Kingston, Ontario, Canada.

Background: Complex fractionated electrograms (EGMs) of the coronary sinus electrograms (CSEs) are employed as a target during radiofrequency ablations (RFA) of atrial fibrillation (AF). Anatomically, CSEs includes both of left atrium (LA), coronary sinus musculature and right atrium (RA) electrograms.

Aim: To determine the significance of fractionated CSE and delayed potentials as a predictor of new-onset AF after radiofrequency ablation (RFA) of isolated atrial flutter (AFL). Read More

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June 2018
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Tricuspid annular plane systolic excursion (TAPSE) in pediatric pulmonary hypertension: Integrating right ventricular ejection efficiency (RVEe) into advanced multi-parametric imaging.

Int J Cardiol 2019 Jan 3;274:296-298. Epub 2018 Jul 3.

Department of Pediatric Cardiology and Critical Care, Hannover Medical School, Germany.

The tricuspid annular plane systolic excursion (TAPSE) has evolved into one of the major echocardiographic indicators of systolic right ventricular (RV) longitudinal function in pediatric pulmonary hypertension (PH). Current RV function research in children with PH focusses on multi-parametric approaches that include TAPSE. The RV ejection efficiency (RVEe) is one of the new variables that reflects the relationship of TAPSE divided by the indexed pulmonary vascular resistance (PVRi) measured by cardiac catheterization. Read More

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January 2019
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