1,334 results match your criteria Trichotillomania


Plucking, Picking, and Pulling: The Hair-Raising History of Trichotillomania.

Int J Trichology 2018 Nov-Dec;10(6):289-290

Department of Dermatology, Wrexham Maelor Hospital, Wrexham, UK.

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http://dx.doi.org/10.4103/ijt.ijt_69_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369640PMC
February 2019

Trichoscopy features of trichotillomania.

Pediatr Dermatol 2019 Feb 11. Epub 2019 Feb 11.

Department of Dermatology, Hospital Clinico Universitario, Valencia, Spain.

Trichotillomania is a form of traction alopecia resulting from repetitive and compulsive hair pulling and plucking. Trichotillomania and patchy alopecia areata may have similar clinical and dermoscopic features in some cases. On trichoscopic examination, the presence of black dots, coiled or hook hair, shafts of varying lengths with fraying or split ends (trichoptilosis), and an absence of exclamation mark hairs and yellow dots are suggestive of trichotillomania. Read More

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http://dx.doi.org/10.1111/pde.13756DOI Listing
February 2019
1 Read

Trichotillomania (hair pulling disorder).

Authors:
Jon E Grant

Indian J Psychiatry 2019 Jan;61(Suppl 1):S136-S139

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.

Trichotillomania is characterized by the repetitive pulling out of one's own hair leading to hair loss and possibly functional impairment. Trichotillomania has been documented in the medical literature since the 19 century. Prevalence studies suggest that trichotillomania is a common disorder (point prevalence estimates of 0. Read More

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http://dx.doi.org/10.4103/psychiatry.IndianJPsychiatry_529_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343418PMC
January 2019
1 Read

A Study of the Histopathological Features of Alopecias on Transverse Sections of Scalp Biopsies.

Indian J Dermatol 2019 Jan-Feb;64(1):47-54

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

Background: Transverse sections of scalp biopsies are performed for the assessment of alopecias and are considered advantageous over vertical sections.

Aim: The aim was to study the histopathological features of alopecias on transverse sections of scalp biopsies.

Methods: It was a descriptive study. Read More

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http://dx.doi.org/10.4103/ijd.IJD_477_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340243PMC
February 2019
2 Reads

Milk Thistle Treatment for Children and Adults with Trichotillomania: A Double-Blind, Placebo-Controlled, Crossover Negative Study.

J Clin Psychopharmacol 2019 Jan 28. Epub 2019 Jan 28.

Background: Data on the pharmacological treatment of trichotillomania are limited. Milk thistle has antioxidant properties and showed promise in trichotillomania in a prior case report. The goal of the current study was to determine the efficacy and tolerability of silymarin in children and adults with trichotillomania. Read More

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http://dx.doi.org/10.1097/JCP.0000000000001005DOI Listing
January 2019

A retrospective review of twelve patients with trichotillomania treated in a psychodermatology service.

Clin Exp Dermatol 2019 Jan 28. Epub 2019 Jan 28.

Dermatology Department, Solihull Hospital, Lode Lane, Solihull, B91 2JL.

Trichotillomania is a condition characterised by the pulling of hair from anywhere on the body and is classified as an obsessive-compulsive and related disorder. Patients with hair disorders are commonly referred to psychodermatology services, and can represent a management challenge. Few publications exist that report outcomes for patients with trichotillomania in real clinical practice. Read More

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http://dx.doi.org/10.1111/ced.13931DOI Listing
January 2019
1 Read

A review of N-acetylcysteine in the treatment of grooming disorders.

Int J Dermatol 2019 Jan 22. Epub 2019 Jan 22.

Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.

Background: Pathologic grooming disorders can lead to clinically significant distress and functional impairment. Studies on treatment of these disorders with selective serotonin reuptake inhibitors (SSRIs) and anticonvulsants have led to inconsistent findings. N-acetylcysteine (NAC) has shown promise in treatment of obsessive-compulsive and related disorders. Read More

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http://doi.wiley.com/10.1111/ijd.14371
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http://dx.doi.org/10.1111/ijd.14371DOI Listing
January 2019
7 Reads

Confirmatory factor analysis of the SLEEP-50 Questionnaire in Trichotillomania (Hair-Pulling Disorder) and Excoriation (Skin-Picking) Disorder.

Psychiatry Res 2019 Jan 7;273:197-205. Epub 2019 Jan 7.

Division of Child and Adolescent Psychiatry, University of California, Los Angeles, CA, USA.

The study objective was to perform a confirmatory factor analysis of the SLEEP-50 Questionnaire (SLEEP-50) in Trichotillomania (Hair-Pulling Disorder) and Excoriation (Skin-Picking) Disorder and compare sleep complaints in adults with Trichotillomania, Excoriation Disorder and non-affected controls. Participants were 234 adults with Trichotillomania, 170 with Excoriation Disorder, and 146 non-affected controls. Participants rated sleep using the SLEEP-50 and Pittsburgh Sleep Quality Index (PSQI). Read More

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http://dx.doi.org/10.1016/j.psychres.2019.01.022DOI Listing
January 2019
2 Reads

Trichotillomania Triggered by Vitamin D Deficiency and Resolving Dramatically With Vitamin D Therapy.

Authors:
İsmail Akaltun

Clin Neuropharmacol 2019 Jan/Feb;42(1):20-21

Gaziantep Dr. Ersin Arslan Training and Research Hospital, Department of Child and Adolescent Psychiatry, Gaziantep, Turkey.

Trichotillomania (TTM) is a disorder characterized by the individual pulling out his hair in a repetitive manner, resulting in significant hair loss, a feeling of tension before the hair pulling, and pleasure during it. Our understanding of the neurobiological basis of TTM is limited. However, the condition in all likelihood involves multiple pathways and a complex interaction between various genetic, psychological, and social factors. Read More

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http://dx.doi.org/10.1097/WNF.0000000000000317DOI Listing
January 2019
1 Read
1.836 Impact Factor

A Pilot Examination of Oxidative Stress in Trichotillomania.

Psychiatry Investig 2018 Dec 7;15(12):1130-1134. Epub 2018 Dec 7.

Department of Psychiatry, University of Cambridge, UK; & Cambridge and Peterborough NHS Foundation Trust, Cambridge, UK.

Objective: Trichotillomania is a relatively common illness whose neurobiology is poorly understood. One treatment for adult trichotillomania, n-acetyl cysteine (NAC), has antioxidative properties, as well as effects on central glutamatergic transmission. Preclinical models suggest that excessive oxidative stress may be involved in its pathophysiology. Read More

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http://dx.doi.org/10.30773/pi.2018.09.07.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6318485PMC
December 2018

The efficacy of biofeedback approaches for obsessive-compulsive and related disorders: A systematic review and meta-analysis.

Psychiatry Res 2018 Dec 20;272:237-245. Epub 2018 Dec 20.

Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; ICVS/3B's - PT Government Associate Laboratory, Braga/Guimarães, Portugal. Electronic address:

Biofeedback is applied to target excessive and/or deficient physiological signals to help patients identifying and self-managing their symptoms. Biofeedback has been employed in psychiatric disorders, including obsessive-compulsive disorder (OCD), mainly by using neural signals - neurofeedback. Recently, OCD has been integrated into the obsessive-compulsive and related disorders (OCD&RD) category (body dysmorphic, hoarding, trichotillomania/hair-pulling, and excoriation/skin-picking disorders). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183163
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http://dx.doi.org/10.1016/j.psychres.2018.12.096DOI Listing
December 2018
8 Reads

Comprehensive behavioral treatment for an adult with sensory-based trichotillomania: An illustrative case study.

Bull Menninger Clin 2018 ;82(4):288-307

Post-doctoral fellow, Medical University of South Carolina, Charleston.

Trichotillomania (TTM) is a poorly understood condition that causes significant impairment, but effective behavioral management strategies exist. The phenomenology of TTM is complex and requires an individualized treatment approach, and there are some important facets of TTM that have only recently been recognized. Specifically, contemporary research indicates that hair pulling is often performed to regulate aversive sensations and provide somatosensory reward. Read More

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http://dx.doi.org/10.1521/bumc.2018.82.4.288DOI Listing
January 2018
1 Read

Best management modality of trichobezoar: A case report.

Int J Surg Case Rep 2018 22;53:458-460. Epub 2018 Nov 22.

King Fahad Military Medical Complex, Dharan, Saudi Arabia.

Introduction: Trichobezoar is a rare condition, usually diagnosed in children and young female especially with psychiatric illness. Diagnosis of trichbezoar is usually dependent on the disease history, examination, diagnostic modality including CT scan. Generally this condition can be treated by endoscopy, laparoscopy or laparotomy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183053
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http://dx.doi.org/10.1016/j.ijscr.2018.11.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275210PMC
November 2018
7 Reads

ISMP Adverse Drug Reactions: Lithium-Induced Cardiomyopathy Fixed Drug Eruption Due to Cetirizine, Levocetirizine, and Hydroxyzine Nivolumab-Induced Myasthenia Gravis Nivolumab-Induced Cholangitic Liver Disease Torsade de Pointes Caused by Psychiatric Polypharmacy Trichotillomania Associated With Aripiprazole.

Hosp Pharm 2018 Dec 27;53(6):371-375. Epub 2018 Aug 27.

Temple University School of Pharmacy, Philadelphia, PA, USA.

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. E-mail Dr. Read More

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http://dx.doi.org/10.1177/0018578718795225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293386PMC
December 2018
2 Reads

Functional neural mechanisms of sensory phenomena in obsessive-compulsive disorder.

J Psychiatr Res 2019 Feb 21;109:68-75. Epub 2018 Nov 21.

Department of Psychiatry, New York University School of Medicine, New York, NY, USA; Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA. Electronic address:

Sensory phenomena (SP) are aversive or uncomfortable sensations that accompany and/or drive repetitive behaviors in obsessive-compulsive disorder (OCD). Although SP are associated with significant distress and may respond less well to standard treatments than harm-related obsessions, little is known about their underlying neurobiology. The present study used functional magnetic resonance imaging (fMRI) to measure brain functioning related to severity of SP during a "body-focused" videos task designed to elicit activation in sensorimotor brain regions. Read More

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http://dx.doi.org/10.1016/j.jpsychires.2018.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347462PMC
February 2019
1 Read

Therapeutic Aspects of Trichotillomania: A Review of Current Treatment Options.

Prim Care Companion CNS Disord 2018 Nov 22;20(6). Epub 2018 Nov 22.

Department of Psychiatry, Central Michigan University College of Medicine, Saginaw, Michigan, USA.

Trichotillomania (TTM) is a disorder characterized by recurrent episodes of hair pulling that affects a growing and diverse patient population. The behavior is a result of conscious or unconscious stimuli aimed at alleviating stress. TTM can be diagnosed, typically by a psychiatrist or dermatologist, with various assessment tools and scales. Read More

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http://www.psychiatrist.com/PCC/article/Pages/2018/v20n06/18
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http://dx.doi.org/10.4088/PCC.18nr02344DOI Listing
November 2018
11 Reads

Use of antipsychotic drugs in dermatology.

Clin Dermatol 2018 Nov - Dec;36(6):765-773. Epub 2018 Aug 16.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Antipsychotic drugs can be beneficial in dermatology because of their both central nervous system and peripheral effects. All antipsychotic drugs have a central postsynaptic dopamine D2 receptor blocking effect, which underlies their antipsychotic action. The antipsychotic drugs have varying degrees of histamine H1-receptor, cholinergic muscarinic receptor, and α1-adrenergic receptor blocking effects, which can affect cutaneous perception and the autonomic reactivity of the skin and can be potentially beneficial in the management of certain histamine or sympathetically mediated dermatologic manifestations (eg, urticaria, pruritus, hyperhidrosis). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183017
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http://dx.doi.org/10.1016/j.clindermatol.2018.08.006DOI Listing
August 2018
20 Reads

Use of antiepileptic mood stabilizers in dermatology.

Clin Dermatol 2018 Nov - Dec;36(6):756-764. Epub 2018 Aug 16.

Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

Several antiepileptic drugs (AEDs) are approved by the US Food and Drug Administration for the treatment of bipolar disorder (valproic acid, divalproex, lamotrigine, carbamazepine) and some cutaneous neuropathic pain syndromes (carbamazepine, gabapentin, pregabalin). The AEDs may be effective in the management of (1) chronic pruritus, including pruritus due systemic disease, including uremia, neuropathic pain, neuropathic pruritus, and complex cutaneous sensory syndromes, especially where central nervous system (CNS) sensitization plays a role; (2) management of emotional dysregulation and the resultant repetitive self-excoriation or other cutaneous self-injury in patients who repetitively stimulate or manipulate their integument to regulate emotions (prurigo nodularis, lichen simplex chronicus, skin picking disorder, trichotillomania); (3) management of dermatologic clinical manifestations associated with autonomic nervous system activation (hyperhidrosis, urticaria, flushing; these often occur in conjunction with psychiatric disorders with prominent autonomic activation and dysregulation, eg, social anxiety disorder, posttraumatic stress disorder); and (4) when certain anticonvulsants have a direct therapeutic effect (eg, in psoriasis); currently the use of AEDs for such cases is largely experimental. Gabapentin (dosage range 300-3600 mg daily) is the most widely studied AED mood stabilizer in dermatology and is especially effective in situations where CNS sensitization is a mediating factor. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183017
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http://dx.doi.org/10.1016/j.clindermatol.2018.08.005DOI Listing
August 2018
17 Reads

Assessment and treatment of trichotillomania (hair pulling disorder) and excoriation (skin picking) disorder.

Clin Dermatol 2018 Nov - Dec;36(6):728-736. Epub 2018 Sep 19.

The OCD and Related Disorders Program, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address:

Recommendations are provided for the assessment and treatment of trichotillomania (hair pulling disorder, or HPD) and excoriation disorder (skin picking disorder, or SPD), two body-focused repetitive behavior (BFRB) disorders, based on their severity, comorbidities, and behavioral style. Habit reversal training (HRT) and stimulus control are first-line behavioral treatments that can be used in cases of all severity levels and may be particularly helpful when pulling or picking is performed with lowered awareness/intention. Acceptance and commitment therapy (ACT) and dialectical behavior therapy (DBT) are behavioral treatments that can be employed to augment HRT/stimulus control, especially when negative emotions trigger the pulling or picking. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183017
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http://dx.doi.org/10.1016/j.clindermatol.2018.08.008DOI Listing
September 2018
7 Reads

Body-focused repetitive behaviors and the dermatology patient.

Clin Dermatol 2018 Nov - Dec;36(6):723-727. Epub 2018 Aug 16.

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA. Electronic address:

Body-focused repetitive behaviors (BFRBs) are psychiatric disorders that involve recurrent pulling and picking one's own body resulting in skin lesions with varying degrees of severity. For that reason, the interface with dermatology is important. Currently, the classified BFRBs are trichotillomania and excoriation disorder. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0738081X183017
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http://dx.doi.org/10.1016/j.clindermatol.2018.08.004DOI Listing
August 2018
14 Reads

Clinical Significance of Trichoscopy in Common Causes of Hair Loss in Children: Analysis of 134 Cases.

Authors:
Khitam Al-Refu

Int J Trichology 2018 Jul-Aug;10(4):154-161

Department of Medicine, Faculty of Medicine, Mutah University, Mutah, Karak, Jordan.

Introduction: Hair loss is a common and distressing clinical complaint in the dermatology clinics. Common causes of hair loss in children include alopecia areata, tinea capitis, traction alopecia, and trichotillomania. Newly, trichoscopy allows differential diagnosis of hair loss in most cases and allows visualization of hair shafts and scalps without the need of removing hair. Read More

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http://dx.doi.org/10.4103/ijt.ijt_101_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192235PMC
November 2018
6 Reads

Identifying standardized definitions of treatment response in trichotillomania: A meta-analysis.

Prog Neuropsychopharmacol Biol Psychiatry 2019 Mar 16;89:446-455. Epub 2018 Oct 16.

Yale Child Study Center, New Haven, CT, United States; Department of Psychiatry, Yale University, New Haven, CT, United States. Electronic address:

Background: Symptom severity in trichotillomania clinical trials is typically rated using the Massachusetts General Hospital Hair Pulling Scale (MGH-HPS) and the National Institute of Mental Health Trichotillomania Severity Scale (NIMH-TSS). There are no universal definitions of treatment response on these scales. The absence of empirically supported definitions of treatment response hampers advances in trichotillomania treatment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02785846183052
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http://dx.doi.org/10.1016/j.pnpbp.2018.10.009DOI Listing
March 2019
7 Reads

Small-Bowel Obstruction Secondary to Ileal Trichobezoar in a Patient with Rapunzel Syndrome.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):559-565. Epub 2018 Sep 18.

Department of Radiology, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Mexico.

Bezoars are conglomerations of undigested foreign material retained in the gastrointestinal tract. Trichobezoar is a compact conglomeration of swallowed hair and constitutes less than 6% of all bezoars. Their most frequent location is in the stomach but they may extend through the pylorus into the small bowel. Read More

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https://www.karger.com/Article/FullText/492810
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http://dx.doi.org/10.1159/000492810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180255PMC
September 2018
12 Reads

Body-focused repetitive behaviors: More prevalent than once thought?

Psychiatry Res 2018 12 2;270:389-393. Epub 2018 Oct 2.

Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX, USA; Department of Psychology, Marquette University, Milwaukee, WI, USA.

Body-focused repetitive behaviors (BFRBs), such as hair pulling, skin picking, and nail biting are common habits, but their pathological manifestations have been considered rare. Growing evidence suggests pathological forms of these behaviors can be conceptualized as a class of related disorders. However, few previous studies have examined the collective prevalence of related pathological BFRBs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183087
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http://dx.doi.org/10.1016/j.psychres.2018.10.002DOI Listing
December 2018
6 Reads

N-acetylcysteine in dermatology.

Indian J Dermatol Venereol Leprol 2018 Nov-Dec;84(6):652-659

Department of Dermatology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

N-acetylcysteine is a mucolytic drug which is commonly used as an antidote for acetaminophen toxicity. It is a thiol compound, which acts as a donor of cysteine, leading to replenishment of glutathione and thus acts as an antioxidant. It also has anti-inflammatory effects, alters the levels of neurotransmitters, inhibits proliferation of fibroblasts and keratinocytes and causes vasodilatation. Read More

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http://www.ijdvl.com/text.asp?2018/84/6/652/241953
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http://dx.doi.org/10.4103/ijdvl.IJDVL_33_18DOI Listing
January 2019
9 Reads

Rapunzel syndrome: a rare form of trichobezoar in the stomach with some extension into the small intestine.

Acta Dermatovenerol Alp Pannonica Adriat 2018 09;27(3):155-157

Department of Gastroenterology, Hepatology, and Nutrition, University Children's Hospital, Ljubljana, Slovenia.

Trichobezoars are gastric foreign bodies rarely found in children. They are mainly composed of swallowed hair. Rapunzel syndrome is a very rare form of trichobezoar characterized by extension of the ingested hair from the stomach into the small intestine or even beyond. Read More

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September 2018
2 Reads

Autism and trichotillomania in an adolescent boy.

Authors:
Ruziana Masiran

BMJ Case Rep 2018 Sep 5;2018. Epub 2018 Sep 5.

Department of Psychiatry, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.

An adolescent with autism spectrum disorder and improperly treated attention deficit hyperactivity disorder presented with recurrent hair pulling. Treatment with selective serotonin reuptake inhibitor and stimulant improved these conditions. Read More

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http://dx.doi.org/10.1136/bcr-2018-226270DOI Listing
September 2018
3 Reads

Critical Review of the Use of Second-Generation Antipsychotics in Obsessive-Compulsive and Related Disorders.

Drugs R D 2018 Sep;18(3):167-189

Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA.

Currently, all second-generation antipsychotics are approved for schizophrenia. Many are also approved for bipolar disorder, with some also approved as adjunctive treatment for depression and autism-related irritability. Second-generation antipsychotics are increasingly being prescribed for indications other than those approved by the Food and Drug Administration, such as in dementia, anxiety, and post-traumatic stress disorder to name a few. Read More

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http://dx.doi.org/10.1007/s40268-018-0246-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131117PMC
September 2018
4 Reads

Trichotillomania (hair pulling disorder): Clinical characteristics, psychosocial aspects, treatment approaches, and ethical considerations.

Dermatol Ther 2018 Aug 28:e12622. Epub 2018 Aug 28.

Università G Marconi, Rome, Italy.

Trichotillomania (hair pulling disorder) is a fairly common but underreported disorder characterized by recurrent episodes of pulling hair from different parts of the body. Currently classified in Diagnostic and Statistical Manual of Psychiatric Disorders (DSM-5) under the heading of the "Obsessive-compulsive spectrum and related disorders." The estimated prevalence data suggest that 0. Read More

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http://dx.doi.org/10.1111/dth.12622DOI Listing
August 2018
17 Reads

An fMRI Pilot Study of Cognitive Flexibility in Trichotillomania.

J Neuropsychiatry Clin Neurosci 2018 Aug 24:appineuropsych18030038. Epub 2018 Aug 24.

From the Department of Psychiatry and Behavioral Neuroscience, University of Chicago (JEG); the Department of Medicine, Computational, Cognitive, and Clinical Neuroimaging Lab, Imperial College, London (RD, AH); the Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom (SRC); and Cambridge and Peterborough NHS Foundation Trust, London (SRC).

Trichotillomania is a relatively common psychiatric condition, although its neurobiological basis is unknown. Abnormalities of flexible responding have been implicated in the pathophysiology of obsessive-compulsive disorder and thus may be relevant in trichotillomania. The purpose of this study was to probe reversal learning and attentional set-shifting in trichotillomania. Read More

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http://dx.doi.org/10.1176/appi.neuropsych.18030038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276993PMC
August 2018
18 Reads

Acceptance and Commitment Therapy for Trichotillomania: A Randomized Controlled Trial of Adults and Adolescents.

Behav Modif 2018 Aug 17:145445518794366. Epub 2018 Aug 17.

1 Utah State University, Logan, UT, USA.

The purpose of this study was to examine acceptance and commitment therapy (ACT) as a standalone treatment for trichotillomania in a randomized controlled trial of adults and adolescents. Participants consisted of a community sample of treatment seeking adults and adolescents with trichotillomania. Of the eligible 39 participants randomized into treatment and waitlist groups, 25 completed treatment and were included in the final analysis. Read More

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http://dx.doi.org/10.1177/0145445518794366DOI Listing
August 2018
8 Reads

Trichotillomania and Trichophagia: Modern Diagnostic and Therapeutic Methods.

Dermatol Ther (Heidelb) 2018 Sep 11;8(3):389-398. Epub 2018 Aug 11.

Department of Dermatology, University of Rzeszów, Rzeszów, Poland.

Trichotillomania is a chronic, mental disease of impulse control, characterized by repetitive, compulsive, and self-induced hair pulling. It can occur at any age but is observed more often in adolescents, with a strong predominance in females. Diagnosis of trichotillomania may be difficult, and its effective treatment challenging. Read More

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http://dx.doi.org/10.1007/s13555-018-0256-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109030PMC
September 2018
1 Read

The psychodynamic significance of trichotillomania: a case study.

Riv Psichiatr 2018 Jul-Aug;53(4):214-217

Cattedra di Psichiatria, Dipartimento di Medicina dei Sistemi, Università di Roma Tor Vergata.

In this paper we present a case of trichotillomania which lasted 33 years, starting with the patient's menarche at 12 years old, and lasting until her first and only pregnancy at 45 years old. We explore the psychodynamic meaning of the hair pulling, both in light of the problems related to introjective and projective processes which, in the kleinian view, gives structure to the internal world and, according to Margaret Mahler, individuation-separation theory. The hypotheses on the significance of this symptom are discovered in part in light of the material which emerged from the patient's intermittent participation in group psychotherapy for nearly five years prior to her pregnancy. Read More

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http://dx.doi.org/10.1708/2954.29698DOI Listing
February 2019

Rapunzel syndrome: how to orient the diagnosis.

Pediatr Rep 2018 May 27;10(2):7689. Epub 2018 Jun 27.

Maternal-Child Department, ASL Verbano-Cusio-Ossola.

Rapunzel syndrome is a rare form of tricobezoar with a tail extending from the stomach into the small bowel; surgical removal is generally required. About 60 cases have been reported and described in the literature since 1968. We present the case of an 8-year-old girl who, during the course of a genetic consultation, was initially assigned with a clinical suspicion of ectodermal dysplasia. Read More

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http://dx.doi.org/10.4081/pr.2018.7689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050472PMC
May 2018
2 Reads

Hair-pulling disorder complicated by skin-picking disorder: An unknown side-effect of dopamine replacement therapy?

Psychiatry Clin Neurosci 2018 Oct 23;72(10):801-802. Epub 2018 Aug 23.

INSERM Unit U1246, University of Nantes, University of Tours, Nantes, France.

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http://dx.doi.org/10.1111/pcn.12769DOI Listing
October 2018
2 Reads

Disentangling Family Life and Hair Pulling: Trichotillomania and Relatedness.

Med Anthropol 2018 10 12;37(7):568-581. Epub 2018 Jul 12.

a Department of Social Anthropology , University of Edinburgh , Edinburgh , Scotland.

Trichotillomania (hair pulling) remains a relatively unknown form of body-focused repetitive behavior (BFRB). Sufferers tend to conceal both the action and its effects from others because of stigmatization, which is strong in both public and domestic spheres. Negative responses from close family members can add significantly to the suffering. Read More

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http://dx.doi.org/10.1080/01459740.2018.1476509DOI Listing
October 2018

Two distinct ontogenies confer heterogeneity to mouse brain microglia.

Development 2018 07 4;145(13). Epub 2018 Jul 4.

Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA

mutant mice show compulsive behavior similar to trichotillomania, a human obsessive-compulsive-spectrum disorder. The only lineage-labeled cells in the brains of mice are microglia, suggesting that defective microglia caused the disorder. What is the source of the microglia? It has been posited that all microglia progenitors arise at embryonic day (E) 7. Read More

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http://dx.doi.org/10.1242/dev.152306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053660PMC
July 2018
10 Reads

Salivary Inflammatory Markers in Trichotillomania: A Pilot Study.

Neuropsychobiology 2017 19;76(4):182-186. Epub 2018 Jun 19.

Department of Psychiatry, University of Cambridge, Cambridge and Peterborough NHS Foundation Trust, Cambridge, United Kingdom.

Background: Immune dysregulation has been hypothesized to be important in the development and pathophysiology of compulsive disorders such as obsessive compulsive disorder (OCD), which has a high comorbid overlap with trichotillomania (both are OC-related disorders). The role of inflammation in the pathophysiology of trichotillomania has garnered little research to date.

Methods: Individuals with trichotillomania provided saliva sample for analysis of inflammatory cytokines. Read More

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https://www.karger.com/Article/FullText/489865
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http://dx.doi.org/10.1159/000489865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098693PMC
June 2018
4 Reads

[Trichotillomania].

Tidsskr Nor Laegeforen 2018 06 12;138(10). Epub 2018 Jun 12.

Trichotillomania, or hair-pulling disorder, is a mental disorder that typically strikes in adolescence and has a chronic course. The condition is frequently accompanied by significant limitations as life unfolds. Comorbidity with depression and anxiety disorders is common. Read More

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http://dx.doi.org/10.4045/tidsskr.17.0599DOI Listing
June 2018
6 Reads

Ectoparasite defence in humans: relationships to pathogen avoidance and clinical implications.

Philos Trans R Soc Lond B Biol Sci 2018 Jul;373(1751)

Department of Anthropology and Center for Behavior, Evolution and Culture, University of California, Los Angeles, Los Angeles, CA 90095-1553, USA.

Currently, disgust is regarded as the main adaptation for defence against pathogens and parasites in humans. Disgust's motivational and behavioural features, including withdrawal, nausea, appetite suppression and the urge to vomit, defend effectively against ingesting or touching sources of pathogens. However, ectoparasites do not attack their hosts via ingestion, but rather actively attach themselves to the body surface. Read More

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http://dx.doi.org/10.1098/rstb.2017.0207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000138PMC
July 2018
1 Read

Trichobezoar-Induced Heartburn in a Teenage Girl: A Case Report.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618776345. Epub 2018 May 18.

University of Toledo Medical center, Toledo, OH, USA.

One of the most commonly encountered medical problems affecting all age groups in health care is abdominal pain. There are many surgical and medical causes behind this symptom; however, a rare cause of abdominal pain and other unspecific abdominal complaints are gastric bezoars. Gastric bezoars are defined as the accumulation of undigested or partially digested foreign materials in the stomach. Read More

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http://dx.doi.org/10.1177/2324709618776345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960857PMC
May 2018
3 Reads

Mindfulness-Based Cognitive Hypnotherapy and Skin Disorders.

Am J Clin Hypn 2018 Jul;61(1):34-44

a University of South Florida , Tampa , FL, USA.

Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo. Read More

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https://www.tandfonline.com/doi/full/10.1080/00029157.2017.1
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http://dx.doi.org/10.1080/00029157.2017.1419457DOI Listing
July 2018
44 Reads

Trichotillomania Ranging from "Ritual to Illness" and as a Rare Clinical Manifestation of Frontotemporal Dementia: Review of Literature and Case Report.

Int J Trichology 2018 Mar-Apr;10(2):84-88

Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.

Frontotemporal dementia (FTD) is the most common form of dementia in the younger age group and often exists with comorbid obsessions and compulsions in up to 80% of the patients. Trichotillomania or compulsive "hair-pulling" disorder is a rare manifestation of FTD and is a poorly evaluated symptom in this condition. The release of "grooming functions" due to frontal disinhibition is often attributed to the evolutionary perspective; however, recent findings also implicate the role of neurotransmitter dysfunction. Read More

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http://dx.doi.org/10.4103/ijt.ijt_100_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939009PMC
May 2018
6 Reads

Salivary sex hormones in adolescent females with trichotillomania.

Psychiatry Res 2018 07 5;265:221-223. Epub 2018 May 5.

Department of Psychiatry, University of Cambridge, UK; Cambridge and Peterborough NHS Foundation Trust, UK.

Trichotillomania is several times more common in women and has peak onset around puberty. The role of sex hormones, however, has received little research. 11 adolescent girls with trichotillomania, post-menarche and not taking birth control, were examined on a variety of clinical measures. Read More

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http://dx.doi.org/10.1016/j.psychres.2018.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985958PMC
July 2018
1 Read

Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania.

PeerJ 2018 17;6:e4635. Epub 2018 Apr 17.

Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Background: Trichotillomania (TTM) is an impulse control disorder characterized by repetitive hair pulling/trimming. Barbering behavior (BB) observed in laboratory animals is proposed as a model of TTM. The neurobiological basis of TTM is unclear, but involves striatal hyperactivity and hypoactivation of the prefrontal cortex. Read More

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https://peerj.com/articles/4635
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http://dx.doi.org/10.7717/peerj.4635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909682PMC
April 2018
7 Reads

Habit reversal training for body-focused repetitive behaviors: a practical guide for the dermatologist.

G Ital Dermatol Venereol 2018 Aug 18;153(4):557-566. Epub 2018 Apr 18.

Department of Dermatology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.

Habit reversal training (HRT) is a clinically effective treatment for body-focused repetitive disorders (BFRDs) such as trichotillomania, onychophagia, and dermatillomania. Despite many dermatology providers knowing the term HRT, very few understand what HRT is and how it actually works. In this article, we give a detailed explanation of HRT and walk the reader through a six-session HRT protocol. Read More

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http://dx.doi.org/10.23736/S0392-0488.18.05949-7DOI Listing
August 2018
3 Reads

Rapunzel syndrome with double simultaneous trichobezoar in a teenager: Clinical Case Report.

Rev Chil Pediatr 2018 Feb;89(1):98-102

Escuela de Medicina, Universidad Marista de Mérida, Mexico.

Resumen: Introduction: Trichobezoars are an intraluminal accumulation of ingested hair. The Rapunzel syndrome refers to the presence of gastric trichobezoars which extend to the small intestine together with trichotillomania and trichophagia, that occur predominantly in psychiatric patients of pediatric age.

Objective: To analyze the clinical course and resolution of this syndrome in a case report. Read More

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http://dx.doi.org/10.4067/S0370-41062018000100098DOI Listing
February 2018
3 Reads

Rapunzel syndrome: a tail too long to tell!

BMJ Case Rep 2018 Apr 5;2018. Epub 2018 Apr 5.

Pediatric Surgery, Lady Hardinge Medical College, New Delhi, India.

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http://dx.doi.org/10.1136/bcr-2018-224756DOI Listing
April 2018
10 Reads

Corrigendum.

Authors:

Behav Modif 2018 Sep 5;42(5):806. Epub 2018 Apr 5.

Keuthen, N.J., Tung, E. Read More

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http://dx.doi.org/10.1177/0145445518769737DOI Listing
September 2018
5 Reads