1,320 results match your criteria Trichotillomania
J Psychiatr Res 2018 Nov 21;109:68-75. Epub 2018 Nov 21.
Department of Psychiatry, New York University School of Medicine, New York, NY, USA; Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA. Electronic address:
Sensory phenomena (SP) are aversive or uncomfortable sensations that accompany and/or drive repetitive behaviors in obsessive-compulsive disorder (OCD). Although SP are associated with significant distress and may respond less well to standard treatments than harm-related obsessions, little is known about their underlying neurobiology. The present study used functional magnetic resonance imaging (fMRI) to measure brain functioning related to severity of SP during a "body-focused" videos task designed to elicit activation in sensorimotor brain regions. Read More
Prim Care Companion CNS Disord 2018 Nov 22;20(6). Epub 2018 Nov 22.
Department of Psychiatry, Central Michigan University College of Medicine, Saginaw, Michigan, USA.
Trichotillomania (TTM) is a disorder characterized by recurrent episodes of hair pulling that affects a growing and diverse patient population. The behavior is a result of conscious or unconscious stimuli aimed at alleviating stress. TTM can be diagnosed, typically by a psychiatrist or dermatologist, with various assessment tools and scales. Read More
Clin Dermatol 2018 Nov - Dec;36(6):765-773. Epub 2018 Aug 16.
Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Antipsychotic drugs can be beneficial in dermatology because of their both central nervous system and peripheral effects. All antipsychotic drugs have a central postsynaptic dopamine D2 receptor blocking effect, which underlies their antipsychotic action. The antipsychotic drugs have varying degrees of histamine H1-receptor, cholinergic muscarinic receptor, and α1-adrenergic receptor blocking effects, which can affect cutaneous perception and the autonomic reactivity of the skin and can be potentially beneficial in the management of certain histamine or sympathetically mediated dermatologic manifestations (eg, urticaria, pruritus, hyperhidrosis). Read More
Clin Dermatol 2018 Nov - Dec;36(6):756-764. Epub 2018 Aug 16.
Department of Medicine, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Several antiepileptic drugs (AEDs) are approved by the US Food and Drug Administration for the treatment of bipolar disorder (valproic acid, divalproex, lamotrigine, carbamazepine) and some cutaneous neuropathic pain syndromes (carbamazepine, gabapentin, pregabalin). The AEDs may be effective in the management of (1) chronic pruritus, including pruritus due systemic disease, including uremia, neuropathic pain, neuropathic pruritus, and complex cutaneous sensory syndromes, especially where central nervous system (CNS) sensitization plays a role; (2) management of emotional dysregulation and the resultant repetitive self-excoriation or other cutaneous self-injury in patients who repetitively stimulate or manipulate their integument to regulate emotions (prurigo nodularis, lichen simplex chronicus, skin picking disorder, trichotillomania); (3) management of dermatologic clinical manifestations associated with autonomic nervous system activation (hyperhidrosis, urticaria, flushing; these often occur in conjunction with psychiatric disorders with prominent autonomic activation and dysregulation, eg, social anxiety disorder, posttraumatic stress disorder); and (4) when certain anticonvulsants have a direct therapeutic effect (eg, in psoriasis); currently the use of AEDs for such cases is largely experimental. Gabapentin (dosage range 300-3600 mg daily) is the most widely studied AED mood stabilizer in dermatology and is especially effective in situations where CNS sensitization is a mediating factor. Read More
Clin Dermatol 2018 Nov - Dec;36(6):728-736. Epub 2018 Sep 19.
The OCD and Related Disorders Program, Massachusetts General Hospital, Boston, Massachusetts, USA. Electronic address:
Recommendations are provided for the assessment and treatment of trichotillomania (hair pulling disorder, or HPD) and excoriation disorder (skin picking disorder, or SPD), two body-focused repetitive behavior (BFRB) disorders, based on their severity, comorbidities, and behavioral style. Habit reversal training (HRT) and stimulus control are first-line behavioral treatments that can be used in cases of all severity levels and may be particularly helpful when pulling or picking is performed with lowered awareness/intention. Acceptance and commitment therapy (ACT) and dialectical behavior therapy (DBT) are behavioral treatments that can be employed to augment HRT/stimulus control, especially when negative emotions trigger the pulling or picking. Read More
Clin Dermatol 2018 Nov - Dec;36(6):723-727. Epub 2018 Aug 16.
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA. Electronic address:
Body-focused repetitive behaviors (BFRBs) are psychiatric disorders that involve recurrent pulling and picking one's own body resulting in skin lesions with varying degrees of severity. For that reason, the interface with dermatology is important. Currently, the classified BFRBs are trichotillomania and excoriation disorder. Read More
Int J Trichology 2018 Jul-Aug;10(4):154-161
Department of Medicine, Faculty of Medicine, Mutah University, Mutah, Karak, Jordan.
Introduction: Hair loss is a common and distressing clinical complaint in the dermatology clinics. Common causes of hair loss in children include alopecia areata, tinea capitis, traction alopecia, and trichotillomania. Newly, trichoscopy allows differential diagnosis of hair loss in most cases and allows visualization of hair shafts and scalps without the need of removing hair. Read More
Clin Gastroenterol Hepatol 2018 Oct 18. Epub 2018 Oct 18.
Unversity of California Davis, Division of Gastroenterology and Hepatology, Sacramento, CA.
Prog Neuropsychopharmacol Biol Psychiatry 2019 Mar 16;89:446-455. Epub 2018 Oct 16.
Yale Child Study Center, New Haven, CT, United States; Department of Psychiatry, Yale University, New Haven, CT, United States. Electronic address:
Background: Symptom severity in trichotillomania clinical trials is typically rated using the Massachusetts General Hospital Hair Pulling Scale (MGH-HPS) and the National Institute of Mental Health Trichotillomania Severity Scale (NIMH-TSS). There are no universal definitions of treatment response on these scales. The absence of empirically supported definitions of treatment response hampers advances in trichotillomania treatment. Read More
Case Rep Gastroenterol 2018 Sep-Dec;12(3):559-565. Epub 2018 Sep 18.
Department of Radiology, Hospital Civil de Guadalajara "Fray Antonio Alcalde", Guadalajara, Mexico.
Bezoars are conglomerations of undigested foreign material retained in the gastrointestinal tract. Trichobezoar is a compact conglomeration of swallowed hair and constitutes less than 6% of all bezoars. Their most frequent location is in the stomach but they may extend through the pylorus into the small bowel. Read More
Psychiatry Res 2018 Dec 2;270:389-393. Epub 2018 Oct 2.
Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX, USA; Department of Psychology, Marquette University, Milwaukee, WI, USA.
Body-focused repetitive behaviors (BFRBs), such as hair pulling, skin picking, and nail biting are common habits, but their pathological manifestations have been considered rare. Growing evidence suggests pathological forms of these behaviors can be conceptualized as a class of related disorders. However, few previous studies have examined the collective prevalence of related pathological BFRBs. Read More
Indian J Dermatol Venereol Leprol 2018 Nov-Dec;84(6):652-659
Department of Dermatology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
N-acetylcysteine is a mucolytic drug which is commonly used as an antidote for acetaminophen toxicity. It is a thiol compound, which acts as a donor of cysteine, leading to replenishment of glutathione and thus acts as an antioxidant. It also has anti-inflammatory effects, alters the levels of neurotransmitters, inhibits proliferation of fibroblasts and keratinocytes and causes vasodilatation. Read More
BMJ Case Rep 2018 Sep 5;2018. Epub 2018 Sep 5.
Department of Psychiatry, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
An adolescent with autism spectrum disorder and improperly treated attention deficit hyperactivity disorder presented with recurrent hair pulling. Treatment with selective serotonin reuptake inhibitor and stimulant improved these conditions. Read More
Drugs R D 2018 Sep;18(3):167-189
Fairleigh Dickinson University School of Pharmacy and Health Sciences, Florham Park, NJ, USA.
Currently, all second-generation antipsychotics are approved for schizophrenia. Many are also approved for bipolar disorder, with some also approved as adjunctive treatment for depression and autism-related irritability. Second-generation antipsychotics are increasingly being prescribed for indications other than those approved by the Food and Drug Administration, such as in dementia, anxiety, and post-traumatic stress disorder to name a few. Read More
Dermatol Ther 2018 Aug 28:e12622. Epub 2018 Aug 28.
Università G Marconi, Rome, Italy.
Trichotillomania (hair pulling disorder) is a fairly common but underreported disorder characterized by recurrent episodes of pulling hair from different parts of the body. Currently classified in Diagnostic and Statistical Manual of Psychiatric Disorders (DSM-5) under the heading of the "Obsessive-compulsive spectrum and related disorders." The estimated prevalence data suggest that 0. Read More
J Neuropsychiatry Clin Neurosci 2018 Aug 24:appineuropsych18030038. Epub 2018 Aug 24.
From the Department of Psychiatry and Behavioral Neuroscience, University of Chicago (JEG); the Department of Medicine, Computational, Cognitive, and Clinical Neuroimaging Lab, Imperial College, London (RD, AH); the Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom (SRC); and Cambridge and Peterborough NHS Foundation Trust, London (SRC).
Trichotillomania is a relatively common psychiatric condition, although its neurobiological basis is unknown. Abnormalities of flexible responding have been implicated in the pathophysiology of obsessive-compulsive disorder and thus may be relevant in trichotillomania. The purpose of this study was to probe reversal learning and attentional set-shifting in trichotillomania. Read More
Behav Modif 2018 Aug 17:145445518794366. Epub 2018 Aug 17.
1 Utah State University, Logan, UT, USA.
The purpose of this study was to examine acceptance and commitment therapy (ACT) as a standalone treatment for trichotillomania in a randomized controlled trial of adults and adolescents. Participants consisted of a community sample of treatment seeking adults and adolescents with trichotillomania. Of the eligible 39 participants randomized into treatment and waitlist groups, 25 completed treatment and were included in the final analysis. Read More
Dermatol Ther (Heidelb) 2018 Sep 11;8(3):389-398. Epub 2018 Aug 11.
Department of Dermatology, University of Rzeszów, Rzeszów, Poland.
Trichotillomania is a chronic, mental disease of impulse control, characterized by repetitive, compulsive, and self-induced hair pulling. It can occur at any age but is observed more often in adolescents, with a strong predominance in females. Diagnosis of trichotillomania may be difficult, and its effective treatment challenging. Read More
Riv Psichiatr 2018 Jul-Aug;53(4):214-217
Cattedra di Psichiatria, Dipartimento di Medicina dei Sistemi, Università di Roma Tor Vergata.
In this paper we present a case of trichotillomania which lasted 33 years, starting with the patient's menarche at 12 years old, and lasting until her first and only pregnancy at 45 years old. We explore the psychodynamic meaning of the hair pulling, both in light of the problems related to introjective and projective processes which, in the kleinian view, gives structure to the internal world and, according to Margaret Mahler, individuation-separation theory. The hypotheses on the significance of this symptom are discovered in part in light of the material which emerged from the patient's intermittent participation in group psychotherapy for nearly five years prior to her pregnancy. Read More
Pediatr Rep 2018 May 27;10(2):7689. Epub 2018 Jun 27.
Maternal-Child Department, ASL Verbano-Cusio-Ossola.
Rapunzel syndrome is a rare form of tricobezoar with a tail extending from the stomach into the small bowel; surgical removal is generally required. About 60 cases have been reported and described in the literature since 1968. We present the case of an 8-year-old girl who, during the course of a genetic consultation, was initially assigned with a clinical suspicion of ectodermal dysplasia. Read More
Psychiatry Clin Neurosci 2018 Oct 23;72(10):801-802. Epub 2018 Aug 23.
INSERM Unit U1246, University of Nantes, University of Tours, Nantes, France.
Med Anthropol 2018 Oct 12;37(7):568-581. Epub 2018 Jul 12.
a Department of Social Anthropology , University of Edinburgh , Edinburgh , Scotland.
Trichotillomania (hair pulling) remains a relatively unknown form of body-focused repetitive behavior (BFRB). Sufferers tend to conceal both the action and its effects from others because of stigmatization, which is strong in both public and domestic spheres. Negative responses from close family members can add significantly to the suffering. Read More
Development 2018 07 4;145(13). Epub 2018 Jul 4.
Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
mutant mice show compulsive behavior similar to trichotillomania, a human obsessive-compulsive-spectrum disorder. The only lineage-labeled cells in the brains of mice are microglia, suggesting that defective microglia caused the disorder. What is the source of the microglia? It has been posited that all microglia progenitors arise at embryonic day (E) 7. Read More
Neuropsychobiology 2017 19;76(4):182-186. Epub 2018 Jun 19.
Department of Psychiatry, University of Cambridge, Cambridge and Peterborough NHS Foundation Trust, Cambridge, United Kingdom.
Background: Immune dysregulation has been hypothesized to be important in the development and pathophysiology of compulsive disorders such as obsessive compulsive disorder (OCD), which has a high comorbid overlap with trichotillomania (both are OC-related disorders). The role of inflammation in the pathophysiology of trichotillomania has garnered little research to date.
Methods: Individuals with trichotillomania provided saliva sample for analysis of inflammatory cytokines. Read More
Tidsskr Nor Laegeforen 2018 06 12;138(10). Epub 2018 Jun 12.
Trichotillomania, or hair-pulling disorder, is a mental disorder that typically strikes in adolescence and has a chronic course. The condition is frequently accompanied by significant limitations as life unfolds. Comorbidity with depression and anxiety disorders is common. Read More
Philos Trans R Soc Lond B Biol Sci 2018 Jul;373(1751)
Department of Anthropology and Center for Behavior, Evolution and Culture, University of California, Los Angeles, Los Angeles, CA 90095-1553, USA.
Currently, disgust is regarded as the main adaptation for defence against pathogens and parasites in humans. Disgust's motivational and behavioural features, including withdrawal, nausea, appetite suppression and the urge to vomit, defend effectively against ingesting or touching sources of pathogens. However, ectoparasites do not attack their hosts via ingestion, but rather actively attach themselves to the body surface. Read More
J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618776345. Epub 2018 May 18.
University of Toledo Medical center, Toledo, OH, USA.
One of the most commonly encountered medical problems affecting all age groups in health care is abdominal pain. There are many surgical and medical causes behind this symptom; however, a rare cause of abdominal pain and other unspecific abdominal complaints are gastric bezoars. Gastric bezoars are defined as the accumulation of undigested or partially digested foreign materials in the stomach. Read More
Am J Clin Hypn 2018 Jul;61(1):34-44
a University of South Florida , Tampa , FL, USA.
Mindfulness-based cognitive hypnotherapy integrates mindfulness, cognitive-behavioral therapy, and hypnotherapy to improve physical, emotional, mental, and/or spiritual aspects of skin disorders. Meditation, including mindfulness meditation, and hypnosis both utilize trance phenomena to help produce focalization and specific improvements in skin disorders through psycho-neuro-endocrine-immunologic mechanisms. Hypnosis, cognitive hypnotherapy, focused meditation, and mindfulness meditation are discussed with respect to improving various skin disorders including acne, acne excoriée, alopecia areata, atopic dermatitis, congenital ichthyosiform erythroderma, dyshidrotic dermatitis, erythema nodosum, erythromelalgia, furuncles, glossodynia, herpes simplex, hyperhidrosis, ichthyosis vulgaris, lichen planus, neurodermatitis, nummular dermatitis, postherpetic neuralgia, prurigo nodularis, pruritus, psoriasis, rosacea, trichotillomania, urticaria, verruca vulgaris, and vitiligo. Read More
Int J Trichology 2018 Mar-Apr;10(2):84-88
Department of Neurology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India.
Frontotemporal dementia (FTD) is the most common form of dementia in the younger age group and often exists with comorbid obsessions and compulsions in up to 80% of the patients. Trichotillomania or compulsive "hair-pulling" disorder is a rare manifestation of FTD and is a poorly evaluated symptom in this condition. The release of "grooming functions" due to frontal disinhibition is often attributed to the evolutionary perspective; however, recent findings also implicate the role of neurotransmitter dysfunction. Read More
Psychiatry Res 2018 07 5;265:221-223. Epub 2018 May 5.
Department of Psychiatry, University of Cambridge, UK; Cambridge and Peterborough NHS Foundation Trust, UK.
Trichotillomania is several times more common in women and has peak onset around puberty. The role of sex hormones, however, has received little research. 11 adolescent girls with trichotillomania, post-menarche and not taking birth control, were examined on a variety of clinical measures. Read More
PeerJ 2018 17;6:e4635. Epub 2018 Apr 17.
Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Background: Trichotillomania (TTM) is an impulse control disorder characterized by repetitive hair pulling/trimming. Barbering behavior (BB) observed in laboratory animals is proposed as a model of TTM. The neurobiological basis of TTM is unclear, but involves striatal hyperactivity and hypoactivation of the prefrontal cortex. Read More
G Ital Dermatol Venereol 2018 Aug 18;153(4):557-566. Epub 2018 Apr 18.
Department of Dermatology, Dell Medical School, University of Texas at Austin, Austin, TX, USA.
Habit reversal training (HRT) is a clinically effective treatment for body-focused repetitive disorders (BFRDs) such as trichotillomania, onychophagia, and dermatillomania. Despite many dermatology providers knowing the term HRT, very few understand what HRT is and how it actually works. In this article, we give a detailed explanation of HRT and walk the reader through a six-session HRT protocol. Read More
Rev Chil Pediatr 2018 Feb;89(1):98-102
Escuela de Medicina, Universidad Marista de Mérida, Mexico.
Resumen: Introduction: Trichobezoars are an intraluminal accumulation of ingested hair. The Rapunzel syndrome refers to the presence of gastric trichobezoars which extend to the small intestine together with trichotillomania and trichophagia, that occur predominantly in psychiatric patients of pediatric age.
Objective: To analyze the clinical course and resolution of this syndrome in a case report. Read More
BMJ Case Rep 2018 Apr 5;2018. Epub 2018 Apr 5.
Pediatric Surgery, Lady Hardinge Medical College, New Delhi, India.
BMC Pediatr 2018 04 4;18(1):125. Epub 2018 Apr 4.
Department of Pediatrics and Neonatology, Guglielmo da Saliceto Hospital, Cantone del Cristo 50, Piacenza, Italy.
Background: Iron deficiency anemia (IDA) and abdominal pain are commonly seen in a pediatric emergency department (8 and 18% incidence respectively in our center). They are manifestations of a wide variety of diseases ranging from benign to immediately life-threatening. Trichobezoar is an under-diagnosed entity that has to be considered in children and adolescents, expecially female, suffering from trichotillomania (compulsion to pull hair) and trichophagy (compulsion to swallow hair). Read More
J Obsessive Compuls Relat Disord 2018 Jan 31;16:14-20. Epub 2017 Oct 31.
University of Michigan, Department of Psychiatry.
Habit Reversal Therapy (HRT) is helpful for many persons suffering from trichotillomania. However successful habit reversal therapy requires awareness of hair pulling behaviors. Available methods to monitor hair pulling behaviors are less than ideal, particularly when sufferers are unaware of their pulling-related behaviors. Read More
Int J Surg Case Rep 2018 21;45:83-86. Epub 2018 Mar 21.
Department of General Surgery, Vijayanagar Institute of Medical Sciences, Ballari, Karnataka, 583104, India.
Introduction: Rapunzel syndrome is a rare condition predominantly found in trichophagic females that occurs when gastric trichobezoar extends beyond the pylorus and into duodenum, jejunum, ileum or even to colon. There are only five cases reported in literature. This case report has been reported in line with the SCARE criteria. Read More
J Dermatol 2018 Jun 22;45(6):692-700. Epub 2018 Mar 22.
Department of Dermatology, Medical University of Warsaw, Warsaw, Poland.
The diagnosis of alopecia areata is usually based on clinical manifestations. However, there are several hair and scalp disorders that share similar clinical features with alopecia areata, such as tinea capitis, trichotillomania or traction alopecia. Trichoscopy as a fast, non-invasive and easy-to-perform technique may help to identify subtle details and establish the correct diagnosis. Read More
Psychiatr Danub 2018 Mar;30(1):79-84
University Department of Paediatrics, Department of Child, and Adolescent Psychiatry, Children's Hospital Zagreb, Klaićeva 16, 10000 Zagreb, Croatia,
Background: The main goal of this study was to analyse and show clinical characteristics and psychiatric comorbidity in 38 participants aged between 10 and 17 with DSM-IV diagnoses of Trichotillomania (TTM) that we were treating at Children's Hospital Zagreb from 2008 to 2017.
Subjects And Methods: We analyzed the data obtained from semi-structured interviews by the criteria of DSM-IV, Youth Self Report (YSR) (Achenbach & Rescorla 2001) and survey that we created.
Results: From 38 participants 21 were girls. Read More
Pan Afr Med J 2017 14;28:142. Epub 2017 Oct 14.
Service d'Ophtalmologie, CHU Hassan II, Fès, Maroc.
Trichotillomania is a neglected psychiatric disorder characterized by the urge to pull out the hair, the eyebrows or any other hair, but rarely the eyelashes. In the Diagnostic and Statistical Manual of Mental Disorders it is defined as habits and pulses disturbance. We here report the case of a girl with trichotillomania involving her left eyelashes due to low self-esteem. Read More
Clin Neuropharmacol 2018 Mar/Apr;41(2):84-85
Department of Child and Adolescent Psychiatry Selçuk University Faculty of Medicine Konya, Turkey Department of Child and Adolescent Psychiatry Selçuk University Faculty of Medicine Konya, Turkey.
Neuroimage Clin 2018 22;17:893-898. Epub 2017 Dec 22.
Department of Psychiatry, University of Cambridge, UK.
Trichotillomania (hair-pulling disorder) is characterized by the repetitive pulling out of one's own hair, and is classified as an Obsessive-Compulsive Related Disorder. Abnormalities of the ventral and dorsal striatum have been implicated in disease models of trichotillomania, based on translational research, but direct evidence is lacking. The aim of this study was to elucidate subcortical morphometric abnormalities, including localized curvature changes, in trichotillomania. Read More
J Appl Behav Anal 2018 Apr 21;51(2):255-262. Epub 2018 Feb 21.
University of Nebraska Medical Center's Munroe-Meyer Institute.
We used a biobehavioral treatment consisting of melatonin and a standardized bed and wake time to decrease one girl's head and mouth touches associated with sleep-related trichotillomania and trichophagia. We remotely coached the girl's caregiver to implement all procedures and monitored response to treatment using a DropCam Pro video camera equipped with night-vision capabilities. Head and mouth touches decreased, and her sleep pattern improved with the combination of treatment strategies. Read More
Skin Appendage Disord 2018 Jan 24;4(1):15-17. Epub 2017 Jun 24.
Universitat Internacional de Catalunya, Barcelona, Spain.
Beard trichotillomania (TTM) is a rather uncommon entity. Hair is not easily plucked from the beard area, as patients need forceps or tweezers to perform their task. The diagnosis of beard TTM can be quite tricky as the location is not the most frequent one. Read More
Int J Surg Case Rep 2018 10;43:25-28. Epub 2018 Feb 10.
Department of Surgery, Mercy University Hospital, Cork, Ireland. Electronic address:
Introduction: Trichotillomania and trichotillophagia can result in huge intraluminal coagulations of hair. Rarely, these can present with gastric perforation. This work has been reported in line with the SCARE criteria (Agha et al. Read More
Psychiatry Res 2018 04 5;262:20-27. Epub 2018 Jan 5.
Department of Psychology, Marquette University, Milwaukee, WI, USA.
Evidence suggests that trichotillomania is characterized by impairment in response inhibition, which is the ability to suppress pre-potent/dominant but inappropriate responses. This study sought to test the feasibility of computerized response inhibition training for children with trichotillomania. Twenty-two children were randomized to the 8-session response inhibition training (RIT; n = 12) or a waitlisted control (WLT; n = 10). Read More
Compr Psychiatry 2018 04 27;82:45-52. Epub 2017 Dec 27.
Department of Psychology, Texas A&M University, 4235 TAMU, College Station, TX 77843-4235, United States; Department of Psychology, Marquette University, P.O. Box 1881, Milwaukee, WI 53201-0327, United States. Electronic address:
Objective: Several compulsive grooming habits such as hair pulling, skin picking, and nail biting are collectively known as body-focused repetitive behaviors (BFRBs). Although subclinical BFRBs are common and benign, more severe and damaging manifestations exist that are difficult to manage. Researchers have suggested that BFRBs are maintained by various cognitive, affective, and sensory contingencies. Read More
Cureus 2017 Nov 29;9(11):e1888. Epub 2017 Nov 29.
Department of Psychiatry, Sidra Medical and Research Center; Weill Cornell Medical College, Cornell University.
N-acetylcysteine (NAC) is a well-known antidote for acetaminophen toxicity and is easily available over the counter. It has antioxidant and anti-inflammatory properties and an established tolerance and safety profile. Owing to its neuroprotective effects, its clinical use has recently expanded to include the treatment of different psychiatric and non-psychiatric disorders. Read More