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Indian J Med Microbiol 2019 Oct-Dec;37(4):536-541

Department of Dermatology, VMMC and Safdarjung Hospital, New Delhi, India.

Introduction: Over the past four decades, there has been an increase in the number of fatal opportunistic invasive trichosporonosis cases especially in immunocompromised hosts.

Objective: The objective of the study is to evaluate the epidemiological, clinical details and antifungal susceptibility pattern of the patients with Trichosporon infections.

Materials And Methods: Twenty-four clinical isolates of Trichosporon species isolated from blood, samples, pleural fluid and nail were included in this study, over a period of 12 years (2005-2016) in a tertiary hospital in North India. Read More

Curr Med Mycol 2020 ;6(1):30-35

Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background And Purpose: Organ transplant recipients are vulnerable to fungal infections. The aim of this study was to determine the prevalence of fungal colonization and infections among patients who underwent various transplantations and molecularly characterize the etiological agents.

Materials And Methods: This study was conducted on candidates for transplantation in Imam Khomeini Hospital, Tehran, Iran, from April 2017 to April 2018. Read More

Infect Drug Resist 2020 20;13:1133-1145. Epub 2020 Apr 20.

National Centre for Microbial Resource (NCMR), National Centre for Cell Science, NCCS Complex, S.P. Pune University, Pune 411 007, Maharashtra, India.

Introduction: Species of genus are part of the common microbiota of humans; however, some of the species are known opportunistic pathogens. Formation of biofilms, resistance to antifungal drugs, and increase in asymptomatic infections demands more studies on isolation, identification and characterization of from clinical samples.

Methods: The present manuscript deals with assessment of authentic yeast identification by three methods viz. Read More

Ann Clin Microbiol Antimicrob 2020 Mar 30;19(1):11. Epub 2020 Mar 30.

Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung City, Taiwan.

Background: Fungal keratitis (FK) has been shown to be a climate-sensitive disease. The differentiation between FK from bacterial keratitis (BK) was difficult. The purpose of this study was to compare the bacteriology and mycology between tropical and subtropical Taiwan and to investigate the independent risk factors for identification of fungi from bacteria. Read More

Sci Total Environ 2020 Jun 23;723:138166. Epub 2020 Mar 23.

Department of Evolutionary Ecology, National Museum of Natural Sciences, Spanish Research Council (CSIC), Madrid, Spain.

Vultures have evolved adaptive mechanisms to prevent infections associated with their scavenging lifestyle. However, food-borne exposure to antimicrobial pharmaceuticals can promote opportunistic infections with adverse outcomes. Here, we used multivariate and network analyses to increase understanding of the behavior of the yeast communities causing oral mycosis outbreaks recently reported in wild nestling cinereous (Aegypius monachus), griffon (Gyps fulvus) and Egyptian (Neophron percnopterus) vultures (CV, GV and EV, respectively) exposed to antibiotics from livestock farming. Read More

Microorganisms 2020 Mar 11;8(3). Epub 2020 Mar 11.

EA Dynamyc UPEC, EnvA, USC Anses, Faculté de Médecine de Créteil, 94000 Créteil, France.

The treatment of invasive fungal infections remains challenging and the emergence of new fungal pathogens as well as the development of resistance to the main antifungal drugs highlight the need for novel therapeutic strategies. Although in vitro antifungal susceptibility testing has come of age, the proper evaluation of therapeutic efficacy of current or new antifungals is dependent on the use of animal models. Mammalian models, particularly using rodents, are the cornerstone for evaluation of antifungal efficacy, but are limited by increased costs and ethical considerations. Read More

BMC Res Notes 2020 Mar 10;13(1):142. Epub 2020 Mar 10.

Department of Microbiology, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.

Objective: Trichosporon asahii is the major causative fungus of disseminated or deep-seated trichosporonosis and forms a biofilm on medical devices. Biofilm formation leads to antifungal drug resistance, so biofilm-related infections are relatively difficult to treat and infected devices often require surgical removal. Therefore, prevention of biofilm formation is important in clinical settings. Read More

Clin Lab 2020 Jan;66(1)

Background: Invasive candidiasis is the most important health-care-associated fungal infection worldwide. In the last two decades, the cause of the increase of fungal infections is immunosuppression or serious underlying diseases. Additionally, Rhodotorula species, Blastoschizomyces capitatus, and Trichosporon species are emerging as important human pathogens in immunocompromised patients with hematological malignancy. Read More

Mycopathologia 2020 Apr 18;185(2):377-388. Epub 2019 Dec 18.

Infectious Diseases, Internal Medicine, Hospital Universitario San Vicente Fundación Universidad de Antioquia, Cra. 51d#62-29, Medellín, Colombia.

Introduction: Cases of invasive Trichosporon infections have increasingly emerged; it is now the second leading cause of yeast bloodstream infections after Candida spp., particularly in the immunosuppressed population, where it often causes breakthrough fungemia with high mortality.

Methods: We present a case report of a breakthrough Trichosporon asahii infection in a patient with acute myeloid leukemia and review all of the cases of breakthrough Trichosporon spp. Read More

J Mycol Med 2020 Apr 6;30(1):100916. Epub 2019 Dec 6.

Departamento Micología, Instituto Nacional de Enfermedades Infecciosas Agudas "Dr. Carlos G. Malbrán", Av Vélez Sarsfield 563, C1282AFF Ciudad Autónoma de Buenos Aires, Argentina. Electronic address:

Here, we describe an invasive infection due to Trichosporon coremiiforme in an HIV positive patient with neutropenia. The strain was first erroneously identified as Trichosporon asahii by conventional methods, but correctly identified by mass spectrometry using matrix-assisted laser desorption/ionization time-of-flight technology (MALDI-TOF MS) and ribosomal DNA sequencing. The infection was successfully resolved after antifungal treatment with amphotericin B and fluconazole. Read More

BMC Res Notes 2019 Nov 29;12(1):779. Epub 2019 Nov 29.

Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Objective: Yeasts are unicellular microorganisms may cause systemic infection in immunocompromised patients. The aim of this study was to identify yeast strains isolated from clinical specimens using molecular techniques.

Results: A total of 202 yeast strains isolated from 341 clinical samples between February 2017 and May 2019. Read More

Front Microbiol 2019 29;10:2196. Epub 2019 Oct 29.

4th Department of Internal Medicine - Division of Hematology, Faculty of Medicine in Hradec Králové, Faculty Hospital in Hradec Králové, Charles University in Prague, Hradec Králové, Czechia.

Background: (formerly , now proposed as ) is a filamentous yeast-like fungus that has recently been described as an emerging pathogen mostly in patients with acute leukemia.

Methods: This is a retrospective study of patients diagnosed with proven and probable infection at the University Hospital, Hradec Králové, Czechia between March 2005 and December 2017. Previous cases were identified from the literature and FungiScope database. Read More

Rev Iberoam Micol 2019 Jul - Sep;36(3):129-138. Epub 2019 Nov 2.

Department of Medical Genetics, KTO Karatay University School of Medicine, Konya, Turkey.

Background: The prevalence of opportunistic yeast infections has increased in recent decades as the result of an increasing immunocompromised patient population.

Aims: To evaluate ribosomal RNA (rRNA) gene sequence to identify medically important yeast species, to investigate the performance of both the rRNA gene internal transcribed spacer (ITS) and D1/D2 region in identifying clinically relevant yeasts, and to compare these results with those of a standard phenotypic method.

Methods: Both regions from 50 yeast strains, comprising 45 clinical isolates and 5 reference strains, were amplified using PCR and then sequenced. Read More

Rev Med Inst Mex Seguro Soc 2019 Jul 31;57(2):74-81. Epub 2019 Jul 31.

Instituto Mexicano del Seguro Social, Hospital de Especialidades “Dr. Bernardo Sepúlveda”, Laboratorio de Investigación Médica en Dermatología y Micología. Ciudad de México, México

Background: Esophageal candidiasis (EC) is the most common cause of infectious esophagitis. So far, its main risk factor has been HIV infection; in recent years, EC has been favoured by the increasing of diabetes mellitus, wide-spread use of acid-lowering agents, broad-spectrum antibiotics, and inhaled steroids. In Mexico EC has been poorly studied. Read More

Med Mycol 2020 Jun;58(4):460-468

Department of Surgical Pathology, Toho University Graduate School of Medicine.

Trichosporon species are some of the most common pathogenic yeasts in Asia, and many are resistant to echinocandin antifungal drugs. Effective treatment of fungal infections requires the selection of appropriate antifungals and the accurate identification of the causal organism. However, in histopathological specimens Trichosporon spp. Read More

Indian J Dermatol 2019 Jul-Aug;64(4):261-265

Department of Microbiology, Gauhati Medical College, Guwahati, Assam, India.

Background: Superficial mycosis is the commonest infections affecting human globally. Though they do not cause mortality, their clinical significance lies in their morbidity, recurrence, and cosmetic disfigurement, thus creating a major public health problem. The infections are more prevalent in the tropical regions. Read More

Fungal Genet Biol 2019 12 9;133:103267. Epub 2019 Sep 9.

Laboratório Especial de Micologia, Disciplina de Infectologia, Universidade Federal de São Paulo, São Paulo, SP, Brazil. Electronic address:

Trichosporon asahii has recently been recognized as an emergent fungal pathogen able to cause invasive infections in neutropenic cancer patients as well as in critically ill patients submitted to invasive medical procedures and broad-spectrum antibiotic therapy. T. asahii is the main pathogen associated with invasive trichosporonosis worldwide. Read More

Future Microbiol 2019 09;14:1159-1170

Department of Microbial Biotechnology, Panjab University, Chandigarh 160014, India.

Staphylococci are common inhabitants at several human body sites and are also implicated in infections either as primary or opportunistic pathogens. These bacteria can thus both contribute to the host defense being a part of the commensalistic microbiota or synergize with the other microbes during the infection process. Among fungi, staphylococci interact synergistically with spp. Read More

BMC Pulm Med 2019 Aug 29;19(1):164. Epub 2019 Aug 29.

Department for Sustainability, Italian National Agency for New Technologies, Energy and Sustainable Economic Development, ENEA C.R Casaccia, 00123, Rome, Italy.

Background: Burkholderia contaminans is one of the 20 closely related bacterial of the Burkholderia cepacia complex, a group of bacteria that are ubiquitous in the environment and capable of infecting people with cystic fibrosis (CF). This species is an emerging pathogen and it has been widely isolated from CF patients in Argentina, Spain, Portugal, Australia, Canada, USA with a low prevalence in Ireland, France, Russia, Switzerland, Czech Republic, and Italy. This is the first report of B. Read More

Mycologia 2019 Sep-Oct;111(5):793-797. Epub 2019 Aug 6.

Núcleo de Ciências Biomédicas, Instituto Adolfo Lutz (IAL) , CLR II, Bauru , São Paulo , Brazil.

This is the first report of the yeast (formerly ) causing disease in humans; its virulence and in vitro behavior against antifungals were also studied. The sample was isolated from biopsy fragments of disseminated lesions on the skin of a pediatric patient with acute myeloid leukemia. The studied virulence factors evidenced that the strain tested negative for secretion of the enzymes proteinase, phospholipase, and hemolysin. Read More

Infect Drug Resist 2019 9;12:2015-2018. Epub 2019 Jul 9.

Department of Parasitology/Mycology, Rouen University Hospital, Rouen, France.

spp. are yeast-like microorganisms responsible for skin, urinary, pulmonary, or bloodstream infections. Due to intrinsic resistance to echinocandins, poor susceptibility to polyenes, and preferred occurrence in immunocompromised patients, such infections are often of poor prognosis. Read More

Vet Ophthalmol 2019 Nov 24;22(6):928-932. Epub 2019 Jul 24.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, California, USA.

A 6-year-old male leopard gecko (Eublepharis macularius) was presented with a 2-year history of recurrent dysecdysis involving the ocular surface of both eyes. Ophthalmic examination revealed ocular surface desiccation and multifocal superficial ulcerative keratitis with patchy remnants of retained shed. Other abnormalities included stomatitis and mandibular and maxillary osteomyelitis. Read More

Cornea 2019 Dec;38(12):1563-1567

Department of Ophthalmology, Cerrahpasa School of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.

Purpose: The purpose of this study was to evaluate the in vitro antifungal effects of n-butyl-2-cyanoacrylate (nB2CA; Histoacryl Blue; B. Braun, Melsungen, Germany) against a variety of different fungal species.

Methods: Inocula taken from suspensions prepared with Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Aspergillus ochraceus, Aspergillus oryzae, Fusarium solanii, Fusarium oxysporum, Trichoderma spp. Read More

Clin Exp Dermatol 2020 Mar 22;45(2):250-253. Epub 2019 Jul 22.

Department of Dermatology, Chelsea and Westminster Hospital, London, UK.

J Assoc Physicians India 2019 Mar;67(3):19-21

Consultant Microbiologist, PD Hinduja Hospital, Mumbai, Maharashtra.

Aim: Trichosporon species are the major emerging opportunistic pathogen in immunocompromised patients. Its diverse refractoriness to conventional antifungal drugs and association with high mortality rate is worrisome. The present study aims to determine the risk factors, treatment outcome and antifungal susceptibility pattern of Trichosporon species in blood stream infections. Read More

Biomed Res Int 2019 14;2019:1803278. Epub 2019 May 14.

The Military Institute of Injury and Reparation, The Seventh Medical Center of PLA General Hospital, Beijing 100700, China.

is the major pathogen causing invasive trichosporonosis. Conventional methods of its detection are time-consuming or costly and often require complex DNA extraction and purification steps, which hinders rapid clinical diagnosis. In this study, we evaluated colony PCR, which directly uses colonies or trace clinical samples as the template for amplification, for rapid detection of infection. Read More

BMJ Case Rep 2019 Jun 18;12(6). Epub 2019 Jun 18.

Respiratory Disease Center, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital, Osaka, Japan.

Association between pulmonary disease and IgA nephropathy (IgAN) has been previously reported. However, no association has been reported between hypersensitivity pneumonitis (HP) and IgAN. Here, we report about a patient with no particular medical history, who experienced worsening dyspnoea in the course of 1 month, with ground-glass opacity on chest CT and no improvement after antibiotic therapy. Read More

Braz J Biol 2020 Jan-Feb;80(1):112-114

Departamento de Zoologia, Universidade de Brasília - Unb, CEP , Brasília, DF, Brasil.

The tegu (Salvator merianae) is the largest lizard found in Brazil and has a wide distribution, occurring in several biomes. The presence of fungi on reptilian eggs initially occurs on infertile eggs, which leads to a subsequent infection in fertile eggs, causing damage and death of embryos. The objective of this study was to identify the fungi that caused lesions in the eggs of tegu in captivity. Read More

Braz J Microbiol 2019 Oct 28;50(4):969-978. Epub 2019 May 28.

Universidade Federal de Alagoas, Instituto de Ciências Biológicas e da Saúde (ICBS), Departamento de Microbiologia, Laboratório de Micologia (LabMicol), Maceió, AL, Brazil.

Superficial and cutaneous mycoses are common in tropical countries, caused by dermatophytes, yeast, and non-dermatophyte molds in different clinical specimens. In order to define the epidemiology of mycoses and the profile of their etiological agents in Alagoas (northeastern Brazil) between 2009 and 2016, we obtained data of patients from the main laboratories of Alagoas, by examining clinical samples with direct microscopy and culture on Sabouraud dextrose agar and ChromagarCandida. A total of 3316 patients were confirmed with mycoses (595 men/2716 women) and 40. Read More

BMC Microbiol 2019 05 28;19(1):113. Epub 2019 May 28.

Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, 611130, China.

Background: Trichosporon is the dominant genus of epidermal fungi in giant pandas (Ailuropoda melanoleuca) and causes local and deep infections. To provide the information needed for the diagnosis and treatment of trichosporosis in giant pandas, the sequence of ITS, D1/D2, and IGS1 loci in 29 isolates of Trichosporon spp. which were isolated from the body surface of giant pandas were combination to investigate interspecies identification and genotype. Read More

BMC Microbiol 2019 05 23;19(1):106. Epub 2019 May 23.

Departamento de Microbiología, Facultad de Ciencias, Unidad de Proteomica y Micosis Humanas, Grupo de Enfermedades Infecciosas, Pontificia Universidad Javeriana, Bogotá, Colombia.

Background: The introduction of MALDI-TOF MS in the clinical microbiology laboratory has modified the approaches for the identification of fungi. Thanks to this tool, it is possible to identify cryptic species, which possess critical susceptibility patterns. Clinical strains were identified using the MicroScan and MALDI-TOF MS systems. Read More

J Pediatric Infect Dis Soc 2019 Dec;8(6):574-577

Universite Claude Bernard Lyon 1, Hospices Civils de Lyon, France.

Med Mycol Case Rep 2019 Jun 28;24:86-89. Epub 2019 Apr 28.

Department of Microbiology, Sri Ramachandra Medical College and Research Institute, SRIHER, Chennai, 600116, India.

We report two cases of complicated Urinary Tract Infection, one with nephrostomy tube left and other with bladder outlet obstruction, caused by . Both patients responded well to antifungal treatment along with change/removal of catheters. In both the cases, correct identification of was done by IGS1 sequencing. Read More

Mycoses 2019 Sep 31;62(9):826-834. Epub 2019 May 31.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Febrile neutropaenia (FNP) is a common cause of morbidity and mortality in immunocompromised patients. Although most infections are caused by bacterial pathogens, fungal infections are becoming increasingly more common. Due to its rarity, the diagnosis of fungal infections in febrile neutropenic patients is often delayed. Read More

J Microbiol Immunol Infect 2019 08 13;52(4):676-678. Epub 2019 Apr 13.

Division of Infectious Diseases, Departments of Internal Medicine, Wan Fang Medical Center, Taipei Medical University, Taipei, Taiwan; Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address:

Int J Trichology 2019 Mar-Apr;11(2):82-85

Department of Microbiology, IGMC, Shimla, Himachal Pradesh, India.

White piedra is a superficial fungal infection of the hair shaft, caused by , a noncandidal yeast characterized by the presence of numerous, discrete, asymptomatic nodules attached to the infected hair shafts. White piedra is considered a disease of tropical regions and occasionally reported from temperate countries. Although such as is well known to cause cutaneous infections, it has been reported as a co-isolate for white piedra along with . Read More

Immun Inflamm Dis 2019 09 20;7(3):125-129. Epub 2019 Apr 20.

Department of Infectious Disease, Medanta The Medicity, Gurgaon, Haryana, India.

Introduction: Trichosporon asahii is an emerging cause of systemic fungal infection in an immunocompromised host. Several life threatening disseminated T. asahii infection in single solid organ (liver or kidney) transplant recipients, in neutropenic and hematological malignancy patients have been reported. Read More

Clin Microbiol Infect 2019 Jul 13;25(7):909.e1-909.e5. Epub 2019 Apr 13.

Laboratório Especial de Micologia, Disciplina de Infectologia, Universidade Federal de São Paulo, Barretos, São Paulo, Brazil. Electronic address:

Objectives: To provide species distribution and antifungal susceptibility profiles of 358 Trichosporon clinical isolates collected from 24 tertiary-care hospitals.

Methods: Species identification was performed by sequencing the IGS1 region of rDNA. Antifungal susceptibility testing for amphotericin B, fluconazole, voriconazole and posaconazole followed the Clinical and Laboratory Standards Institute reference method. Read More

J Mycol Med 2019 Jun 18;29(2):120-126. Epub 2019 Mar 18.

Department of Clinical Laboratory, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China. Electronic address:

Apiotrichum mycotoxinivorans (formerly Trichosporon mycotoxinivorans) has long been used to degrade fungal toxins in livestock feed. However, clinic reports about this type of fungus are rare. In this study, we report the morphology, biochemistry, and molecular characteristics of an A. Read More

Infez Med 2019 Mar;27(1):93-96

Dipartimento Scienze di Laboratorio e Infettivologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy; Istituto di Clinica delle Malattie Infettive, Universitá Cattolica del Sacro Cuore, Rome, Italy.

Trichosporon urinary tract infection (UTI) is an unusual emerging infection, caused mostly by Trichosporon asahii, described especially in hospitalized patients. To date the interpretation and management of Trichosporon positive urinary culture remains a diagnostic and therapeutic dilemma for which there are no precise indications, and the challenge can be even more complicated in comorbid frail elderly patients. Triazoles are known to be the most effective antifungal drugs but can raise concerns about pharmacological interaction. Read More

Microb Pathog 2019 May 14;130:219-225. Epub 2019 Mar 14.

Department of Pathology and Legal Medicine, School of Medicine, Specialized Medical Mycology Center, Postgraduate Program in Medical Microbiology, Federal University of Ceará, Fortaleza-CE, Brazil; School of Veterinary, Postgraduate Program in Veterinary Science, State University of Ceará, Fortaleza-CE, Brazil.

Trichosporon spp. have been increasingly recognized as an important pathogen of invasive and disseminated infections in immunocompromised patients. These species are prone to form biofilms in medical devices such as catheters and prosthesis, which are associated with antifungal resistance and therapeutic failure. Read More

J Pediatr Hematol Oncol 2020 Apr;42(3):e193-e194

Department of Pharmacy Practice, Amrita School of Pharmacy.

Trichosporon asahii is a rare opportunistic fungal pathogen that causes fatal systemic infection in immunocompromised patients. Neutropenia developing due to malignancies is an important risk factor for fungal infection. Invasive infections due to T. Read More

Med Mycol 2019 Nov;57(8):1038-1045

Faculty of Medicine, Post Graduate Program in Medical Microbiology, Federal University of Ceará, Brazil.

Trichosporon species have been considered important agents of opportunistic systemic infections, mainly among immunocompromised patients. Infections by Trichosporon spp. are generally associated with biofilm formation in invasive medical devices. Read More

Braz J Microbiol 2019 Jan 4;50(1):99-105. Epub 2018 Dec 4.

Department of Clinical Microbiology Laboratory, The First Affiliated Hospital of Soochow University, No. 188 Shizi Street, Soochow, 215006, China.

In this multicenter study, we compared the performance of the Bruker Biotyper MS system and VITEK 2 YST systems for invasive yeast identification, investigated the distribution of isolated species, and evaluated the antifungal susceptibility profiles of Candida albicans, Candida parapsilosis, and Candida tropicalis. In cases of discrepant results lack of identification with either method, molecular identification techniques were employed. We tested 216 clinical isolates, and concordance between the two methods was observed for 192/216 isolates (88. Read More

Med Mycol Case Rep 2019 Mar 26;23:26-28. Epub 2018 Oct 26.

Brooke Army Medical Center, 3551 Roger Brooke Drive, San Antonio, TX, USA.

Patients with toxic epidermal necrolysis, a condition that causes full thickness epidermal necrosis that affects over 30% of the skin surface and mucosal membranes, often develop comorbid infections throughout the recovery of the disease [1]. While most commonly these are related to a bacterial source, infections due to viral, mycobacterial, and rarely fungal organisms occur. We present a case of a patient who developed a deep cutaneous fungal infection caused by Trichosporon asahii and discuss the management. Read More

J Lab Physicians 2018 Oct-Dec;10(4):464-470

Department of Microbiology, Jagadguru Sri Shivarathreeshwara Medical College, Mysore, Karnataka, India.

Urinary tract infections (UTIs) caused by fungi, frequently associated with medical devices, have increased and caused great morbidity and mortality among hospitalized patients. Difficulties on different species identification as well as the lack of standardized sensitivity tests , contribute to the limited information available on epidemiology, diagnosis, and therapeutics of infections. There are only sporadic reports of UTI caused by reported from India. Read More

J Lab Physicians 2018 Oct-Dec;10(4):380-386

Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Background: Invasive infections due to spp. have increased recently and are frequently associated with indwelling medical devices. Such infections which are associated with biofilm formation do not respond to the routinely used antifungal agents and are often persistent, associated with high mortality rate. Read More

J Med Microbiol 2019 Jan 27;68(1):81-86. Epub 2018 Nov 27.

National Institute of Health Dr. Ricardo Jorge - Reference Unit for Parasitic and Fungal Infections - Infectious Diseases Department, Lisbon, Portugal.

Purpose: Tissue samples from patients with suspicion of deep or subcutaneous fungal infections were analysed at the Portuguese Reference Mycology Laboratory according to a proposed diagnostic approach, which aims to constitute a rapid and accurate diagnosis for these fungal infections.

Methodology: Forty-six tissue biopsy samples were analysed over a period of 26 months, using a diagnostic approach that includes culture, panfungal PCR and Aspergillus-directed PCR.Results/Key findings. Read More

J Cutan Pathol 2019 Feb 18;46(2):159-161. Epub 2018 Dec 18.

Department of Dermatology, Columbia University Medical Center, New York, New York.

We report a case of disseminated Trichosporon asahii in a patient on systemic antifungal therapy who presented with multiple cutaneous nodules suggestive of fungal infection. Histologic features resembled neutrophilic eccrine hidradenitis but staining with periodic acid-Schiff and Gomori methenamine silver confirmed the clinical diagnosis. This case highlights the importance of maintaining suspicion for trichosporonosis and contextualizing histologic findings within the underlying clinical picture. Read More

J Clin Microbiol 2019 02 30;57(2). Epub 2019 Jan 30.

Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China

A total of 133 clinical isolates were collected in the National China Hospital Invasive Fungal Surveillance Net (CHIF-NET) program in 2009 to 2016. Accurate identification was performed by sequencing of the intergenic spacer 1 (IGS1) region. Among these isolates, (108 isolates [81. Read More