Considerations in surgical management of a Buschke-Lowenstein tumor in Netherton syndrome: A case report.
Pediatr Dermatol 2017 Nov;34(6):e328-e330
Department of Dermatology, Great Ormond Street Hospital, London, UK.
Netherton syndrome is an autosomal recessive ichthyosis caused by mutations in SPINK5, with the classic triad of linearis circumflexa, trichorrhexis invaginata, and atopy. There are few reports of surgical management in individuals with Netherton syndrome and clinicians may be reluctant to operate for fear of wound-healing complications. This report describes a pediatric case of a Buschke-Lowenstein tumor of the natal cleft in a patient with Netherton syndrome that had failed to respond to medical management. Read More