8,058 results match your criteria Trichomoniasis


Supplemental testing is required to maintain control following a transition from Pap smear to HPV DNA testing for cervical screening: a mathematical modelling study.

Sex Transm Infect 2019 Apr 16. Epub 2019 Apr 16.

Kirby Institute, UNSW Sydney, Sydney, New South Wales, Australia.

Objectives: Using mathematical modelling, we have previously shown that the prevalence of infection with (TV) is likely to increase in the general population in Australia with the transition from Pap smear-based cervical screening to human papillomavirus (HPV) DNA testing. Here we use the existing model to estimate the level of supplemental testing required to maintain TV control.

Methods: A compartmental mathematical model describing the transmission of TV in the general heterosexual population in Australia was used to evaluate the impact of a range of screening scenarios on TV prevalence over time following the transition to HPV DNA testing for cervical screening. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053845DOI Listing

Borderline personality disorder is associated with an increased risk of sexually transmitted infections: A nationwide population-based cohort study in Taiwan.

Sex Transm Infect 2019 Apr 13. Epub 2019 Apr 13.

Department of Psychiatry, Tzu Chi General Hospital, and School of Medicine, Tzu Chi University, Hualien, Taiwan

Background: Several features of borderline personality disorder (BPD) are likely to be associated with sexual health problems, such as unstable attachment, unstable sexual identity and sexual impulsivity. Since the issue of sex is not openly discussed in Taiwanese society, sexual health needs, including screening and prevention of sexually transmitted infections (STI), are often neglected in this population.

Objective: The study aims to determine whether BPD is associated with an increased risk of subsequent STI in Taiwan. Read More

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http://sti.bmj.com/lookup/doi/10.1136/sextrans-2018-053812
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http://dx.doi.org/10.1136/sextrans-2018-053812DOI Listing
April 2019
6 Reads

Captive Agamid lizards in Germany: Prevalence, pathogenicity and therapy of gastrointestinal protozoan and helminth infections.

Comp Immunol Microbiol Infect Dis 2019 Apr 15;63:74-80. Epub 2019 Jan 15.

Exomed GbR, Schönhauserstr. 62, 13127 Berlin, Germany.

Reptiles are becoming popular pets in many parts of the world. They are also known to harbor numerous gastrointestinal parasites. We used faecal smears to examine 748 stool samples from 14 different agamid lizard species. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01479571193000
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http://dx.doi.org/10.1016/j.cimid.2019.01.005DOI Listing
April 2019
1 Read

Evaluation of the 'Colli-Pee', a first-void urine collection device for self-sampling at home for the detection of sexually transmitted infections, versus a routine clinic-based urine collection in a one-to-one comparison study design: efficacy and acceptability among MSM in Belgium.

BMJ Open 2019 Apr 3;9(4):e028145. Epub 2019 Apr 3.

Department of Clinical Sciences, HIV/STI Reference Laboratory, Institute of Tropical Medicine, Antwerp, Belgium.

Objectives: Pre-exposure prophylaxis (PrEP) users are screened bi-annual for sexually transmitted infections (STIs). A novel device, called the Colli-Pee, collects first-void urine in a standardised way and the collector tube can be easily delivered by regular post to a certified laboratory. The aim of the study was a one-to-one comparison between the STI test results obtained with the urine collected in the clinic, versus urine collected at home in a real-life setting by Men who have Sex with Men (MSM) in Belgium. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-028145DOI Listing
April 2019
1 Read

Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection.

PLoS One 2019 4;14(4):e0213975. Epub 2019 Apr 4.

Institute of Infectious Disease and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.

The genital tract of African women has been shown to differ from what is currently accepted as 'normal', defined by a pH≤4.5 and lactobacilli-dominated microbiota. Adolescent girls and young women (AGYW) from sub-Saharan Africa are at high risk for HIV, and we hypothesized that specific biological factors are likely to be influential. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213975PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448899PMC
April 2019
2 Reads

Sexually Transmitted Diseases in the Emergency Department.

Emerg Med Clin North Am 2019 May;37(2):165-192

Prisma Health, University of South Carolina School of Medicine Greenville, 701 Grove Road, Greenville, SC 29605, USA. Electronic address:

Sexually transmitted diseases (STDs) continue to be underrecognized leading to devastating health and economic consequences. Emergency clinicians play an important role in diagnosing and managing STDs and in improving health care outcomes for both the patient and their partners. In addition, antibiotic resistance and emerging infections continue to challenge providers in clinical practice. Read More

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http://dx.doi.org/10.1016/j.emc.2019.01.001DOI Listing
May 2019
1 Read

Evaluation of the BD MAX™ Vaginal Panel for the detection of vaginal infections in a sexual health service in the UK.

Authors:
Jackie Sherrard

Int J STD AIDS 2019 Mar 8;30(4):411-414. Epub 2019 Jan 8.

Department of Sexual Health, Buckinghamshire Healthcare NHS Trust, Wycombe General Hospital, Wycombe, UK.

The aim of this study is to compare the performance of the BD MAX™ Vaginal Panel (Becton, Dickinson and company, Franklin Lakes, NJ, USA) in the diagnosis of bacterial vaginosis (BV), candidiasis and trichomoniasis with current standard tests in a UK specialist sexual health service. Women with abnormal vaginal discharge attending the service who had not used douches or vaginal treatment in the preceding 48 hours had two vulvovaginal swabs taken: one for Chlamydia and gonorrhoea nucleic acid amplification test (NAAT) and one for testing on the BD MAX™ Vaginal Panel on the BD MAX System. Speculum examination was then performed and vaginal swabs taken for vaginal pH, and microscopy of vaginal secretions: Gram stain for Candida and BV using the Hay-Ison score and wet-mount for clue cells and Trichomonas vaginalis (TV). Read More

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http://dx.doi.org/10.1177/0956462418815284DOI Listing
March 2019
2 Reads

Performance Evaluation of a New Culture Colorimetric Detection Assay.

Eurasian J Med 2019 Feb 30;51(1):5-7. Epub 2018 Nov 30.

Department of Clinical Microbiology and Virology, Polyclinic Tor Vergata Foundation, Rome, Italy.

Objective: To evaluate the performance of the culture colorimetric detection assay MYCO WELL D-ONE (MWD-ONE), designed to detect sexually transmitted infections using real-time polymerase chain reaction (PCR) as a reference method.

Materials And Methods: One hundred and ten urogenital samples were screened for (GV), (TV), (MH), , and (UU)/ (UP) using the MWD-ONE and real-time PCR assays species Real-TM Quant and Anyplex II STI-7 Detection, respectively.

Results: GV was detected in 33 samples by both the MWD-ONE and real-time PCR, while 6 samples gave discordant results. Read More

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http://dx.doi.org/10.5152/eurasianjmed.2018.17364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422620PMC
February 2019
1 Read

Sexually Transmitted Infection Among Adolescents and Young Adults With Bipolar Disorder: A Nationwide Longitudinal Study.

J Clin Psychiatry 2019 Mar 12;80(2). Epub 2019 Mar 12.

Department of Psychiatry, No. 201, Shih-Pai Rd, Sec. 2, 11217, Taipei, Taiwan.

Background: Evidence has shown a significant association between bipolar disorder and prevalence of risky sexual behaviors. However, the relationship between bipolar disorder and risk for sexually transmitted infections (STIs) requires further investigation, as do the effects of bipolar disorder medications on STI risk.

Methods: In the present study, data from 26,028 adolescents and young adults with bipolar disorder (ICD-9-CM code 296 except 296. Read More

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http://dx.doi.org/10.4088/JCP.18m12199DOI Listing
March 2019
4 Reads
5.498 Impact Factor

Evaluation of the vaginal microbiome in clinical diagnosis and management of vaginal infectious diseases.

Chin Med J (Engl) 2019 Mar 19. Epub 2019 Mar 19.

Department of Microecological Laboratory, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Objective: The Vaginal Microecology Evaluation System (VMES) is a technical and economically feasible tool to assess the vaginal microbiomes of gynecological outpatients. The aim of this review was to introduce knowledge on the potential changes that can occur in the vaginal microbiome and how to use the Evaluation System to diagnose and manage a broad range of vaginal infections.

Data Sources: This review was based on data in articles published in PubMed up to December 10, 2018, with the following keywords: "Vaginal microecosystem", "vaginal microbiome", "vaginal microbiota", and "vaginal flora". Read More

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http://dx.doi.org/10.1097/CM9.0000000000000211DOI Listing
March 2019
1 Read

Infection with Trichomonas vaginalis increases the risk of psychiatric disorders in women: a nationwide population-based cohort study.

Parasit Vectors 2019 Mar 12;12(1):88. Epub 2019 Mar 12.

Department of Laboratory Medicine, Linkou Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Background: Trichomonas vaginalis is a protozoan parasite that causes trichomoniasis and annually infects approximately 276 million people worldwide. We observed an ambiguously higher probability of trichomoniasis in patients from the psychiatric department of Tri-Service General Hospital. Herein, we aimed to investigate the association between trichomoniasis and the risk of developing psychiatric disorders. Read More

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http://dx.doi.org/10.1186/s13071-019-3350-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417068PMC
March 2019
4 Reads
3.430 Impact Factor

Sexually transmitted infections, the silent partner in HIV-infected women in Zimbabwe.

South Afr J HIV Med 2019 23;20(1):849. Epub 2019 Jan 23.

Newlands Clinic, Zimbabwe.

Background: Coinfection rates of HIV and sexually transmitted infections (STIs) are not widely reported in Zimbabwe and no local guidelines regarding the screening of STIs in people living with HIV exist.

Objectives: This cross-sectional study was conducted to determine the prevalence and associated risk factors for STI coinfection in a cohort of HIV-infected women.

Methods: Between January and June 2016, 385 HIV-infected women presenting for routine cervical cancer screening were tested for five STIs: (NG), (CT), (TV), Herpes Simplex Virus (HSV) type 2 and (TP). Read More

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http://dx.doi.org/10.4102/sajhivmed.v20i1.849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407315PMC
January 2019
2 Reads

Addressing the constraints of Tritrichomonas foetus sample collection in remote areas: lyophilized modified Diamond's media as a substitute for liquid medium.

Parasitology 2019 Mar 12:1-4. Epub 2019 Mar 12.

Sydney School of Veterinary Science, Faculty of Science, University of Sydney,New South Wales, 2006,Australia.

Bovine trichomoniasis is a notifiable, reproductive disease of cattle caused by the parasite Tritrichomonas foetus. Culturing with modified Diamond's medium (MDM) is required to increase the low number of organisms received from a preputial sample, but is limited in application to remote areas as it requires continuous cold chain storage. This study utilized lyophilization to sustain the viability of MDM during transport in lieu of a continuous cold chain. Read More

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http://dx.doi.org/10.1017/S0031182019000258DOI Listing

Cooperative interactions between and associated bacteria enhance paracellular permeability of the cervicovaginal epithelium by dysregulating tight junctions.

Infect Immun 2019 Mar 11. Epub 2019 Mar 11.

School of Biological Science, University of Auckland, Auckland, New Zealand

The human protozoan is the causative agent of trichomoniasis, a prevalent sexually transmitted infection, which is accompanied by a species-diversified vaginal microbiota named community state type IV (CST-IV). Coincidently, CST-IV includes species associated with bacterial vaginosis (e.g. Read More

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http://dx.doi.org/10.1128/IAI.00141-19DOI Listing
March 2019
2 Reads

Immune Response of BALB/c Mice toward Putative Calcium Transporter Recombinant Protein of Trichomonas vaginalis.

Korean J Parasitol 2019 Feb 26;57(1):33-38. Epub 2019 Feb 26.

Laboratorio de Bioquímica y Genética Molecular, Facultad de Química de la Universidad Autónoma de Yucatán, Mérida 97069, México.

Trichomoniasis is a common sexually transmitted infection caused by Trichomonas vaginalis, which actually does not exist a vaccine for control or prevention. Thus, the identification of new and potent immunogens in T. vaginalis, which can contribute to the development of a vaccine against this parasite, is necessary. Read More

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http://dx.doi.org/10.3347/kjp.2019.57.1.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409216PMC
February 2019
2 Reads

Comparison of Two PCR Assays for Trichomonas vaginalis.

Korean J Parasitol 2019 Feb 26;57(1):27-31. Epub 2019 Feb 26.

Department of Environmental Biology and Medical Parasitology, Hanyang University College of Medicine, Seoul 04763, Korea.

PCR is known to be the most sensitive method for diagnosing Trichomonas vaginalis infections. This study aimed to compare the sensitivity of a PCR assay for trichomoniasis (HY-PCR) developed in Hanyang University with the use of a Seeplex Ace Detection Kit®, using urine collected from four Korean men with prostatic disease. Overall, HY-PCR was more sensitive than the Seeplex Kit. Read More

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http://dx.doi.org/10.3347/kjp.2019.57.1.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409213PMC
February 2019

Comparison of Seropositivity to Trichomonas vaginalis between Men with Prostatic Tumor and Normal Men.

Korean J Parasitol 2019 Feb 26;57(1):21-25. Epub 2019 Feb 26.

Department of Urology, Hanyang University College of Medicine, Seoul 04763, Korea.

Trichomoniasis is the most common curable sexually-transmitted infection. Most Trichomonas vaginalis-infected men are asymptomatic and can remain undiagnosed and untreated, and this has been thought to result in chronic persistent prostatic infection. Chronic inflammation is regarded as the major factor in the pathogenesis and progression of benign prostatic hyperplasia (BPH) and prostatic cancer (PCa). Read More

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http://dx.doi.org/10.3347/kjp.2019.57.1.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409223PMC
February 2019
1 Read

Acquisition of Sexually Transmitted Infections among Women Using a Variety of Contraceptive Options: A prospective Study among High-risk African Women.

J Int AIDS Soc 2019 Feb;22(2):e25257

University of Washington, Seattle, WA, USA.

Introduction: In many African settings, women concurrently face substantial risk of human immunodeficiency virus type 1 (HIV-1) infection, sexually transmitted infections (STIs) and unintended pregnancies. Few studies have evaluated STI risk among users of hormonal implants and copper intrauterine devices (IUDs) although these long-acting reversible contraceptive methods are being promoted widely because of their benefits. Within a prospective study of women at risk for HIV-1, we compared the risk of acquisition of Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis among women using different contraceptive methods. Read More

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http://dx.doi.org/10.1002/jia2.25257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393855PMC
February 2019
4 Reads

Primary HIV prevention in pregnant and lactating Ugandan women: A randomized trial.

PLoS One 2019 25;14(2):e0212119. Epub 2019 Feb 25.

Department of Medicine, Johns Hopkins University, Baltimore, MD, United States of America.

Background: The 'Primary HIV Prevention among Pregnant and Lactating Ugandan Women' (PRIMAL) study aimed to assess the effectiveness of an enhanced HIV counseling intervention for preventing HIV acquisition among HIV-uninfected mothers during pregnancy and throughout the breastfeeding period.

Methods: We conducted an unblinded randomized control trial between 22 February 2013 and 22 April 2016 to assess the effectiveness of an extended repeat HIV testing and enhanced counseling (ERHTEC) intervention aimed at preventing primary HIV infection among HIV-uninfected pregnant and lactating women in Uganda. HIV-uninfected pregnant women aged 15-49 were enrolled 1:1 individually or in couples together with their partner. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212119PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388930PMC
February 2019
3 Reads

Perceived stress and incident sexually transmitted infections in a prospective cohort.

Ann Epidemiol 2019 Apr 26;32:20-27. Epub 2019 Jan 26.

Department of Epidemiology and Biostatistics, University of Maryland School of Public Health, College Park, MD.

Purpose: Psychosocial stress has been associated with susceptibility to many infectious pathogens. We evaluated the association between perceived stress and incident sexually transmitted infections (STIs; Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis genital infections) in a prospective study of women. Stress may increase vulnerability to STIs by suppressing immune function and altering the protective vaginal microbiota. Read More

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http://dx.doi.org/10.1016/j.annepidem.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446572PMC

Age-related variation in the oral microbiome of urban Cooper's hawks (Accipiter cooperii).

BMC Microbiol 2019 Feb 21;19(1):47. Epub 2019 Feb 21.

School of Plant Sciences, The University of Arizona, Tucson, USA.

Background: Bird species worldwide are affected by trichomoniasis caused by the protist Trichomonas gallinae. In avivorous raptors such as Cooper's hawks (Accipiter cooperii), nestlings are more susceptible than fledglings and adults. Previous research suggested a link between oral pH and susceptibility: the oral pH of fledgling and adult hawks is more than seven times more acidic than that of nestlings. Read More

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http://dx.doi.org/10.1186/s12866-019-1413-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385412PMC
February 2019

Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study.

BMJ Open 2019 Feb 19;9(2):e026888. Epub 2019 Feb 19.

Centre for the AIDS Programme in South Africa (CAPRISA), Durban, South Africa.

Objectives: Syndromic management of sexually transmitted infections (STIs) omits asymptomatic infections, particularly among women. Accurate point-of-care assays may improve STI care in low- and middle-income countries (LMICs). We aimed to evaluate the diagnostic performance of the Xpert / (CT/NG) and OSOM (TV) Test as part of a STI care model for young women in South Africa. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02688
Publisher Site
http://dx.doi.org/10.1136/bmjopen-2018-026888DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367982PMC
February 2019
10 Reads
2.063 Impact Factor

Trichomonas vaginalis virus (TVV) among women with trichomoniasis and associations with demographics, clinical outcomes, and metronidazole resistance.

Clin Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Division of Infectious Diseases, University of Alabama at Birmingham.

Background: Trichomonas vaginalis virus (TVV) is a non-segmented, 4.5-5.5 kbp, double-stranded RNA virus infecting T. Read More

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http://dx.doi.org/10.1093/cid/ciz146DOI Listing
February 2019
6 Reads

Does Male Circumcision Reduce Women's Risk of Sexually Transmitted Infections, Cervical Cancer, and Associated Conditions?

Front Public Health 2019 31;7. Epub 2019 Jan 31.

Department of Urology, University of Washington School of Medicine, Seattle, WA, United States.

Male circumcision (MC) is proven to substantially reduce men's risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to determine the relationship between MC and risk of STIs and associated conditions in women. Database searches by "circumcision women" and "circumcision female" identified 68 relevant articles for inclusion. Read More

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http://dx.doi.org/10.3389/fpubh.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365441PMC
January 2019
4 Reads

The prevalence of Mycoplasma genitalium and association with HIV infection in symptomatic patients, Johannesburg, South Africa, 2007-2014.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

Centre for HIV & STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.

Background: Mycoplasma genitalium is associated with genital discharge syndrome, but limited prevalence data is available in South Africa. The prevalence rates of M. genitalium infection and HIV co-infection were determined in urogenital specimens collected from male and female patients presenting with genital discharge syndrome to a primary health care centre in Johannesburg, South Africa from 2007 through 2014. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000984DOI Listing
February 2019
3 Reads

Acceptability and feasibility of sexually transmissible infection screening among pregnant women in Hanoi, Vietnam.

Sex Health 2019 Feb 11. Epub 2019 Feb 11.

Vietnam currently has no antenatal screening program for curable sexually transmissible infections (STIs). The aim of this study was to determine the prevalence of curable STIs, correlates of infections and assess the acceptability and feasibility of antenatal STI screening in Hanoi, Vietnam. A study involving 800 pregnant women visiting Ha Dong Hospital in Hanoi, Vietnam from June 2016 to July 2017, was conducted. Read More

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http://dx.doi.org/10.1071/SH18041DOI Listing
February 2019
3 Reads

Female sex workers in Kigali, Rwanda: a key population at risk of HIV, sexually transmitted infections, and unplanned pregnancy.

Int J STD AIDS 2019 Feb 6:956462418817050. Epub 2019 Feb 6.

1 Projet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.

Female sex workers (FSWs) were recruited from known hotspots in Kigali, Rwanda, and offered free, anonymous human immunodeficiency virus (HIV) counseling and testing, diagnosis and treatment of sexually transmitted infections (STIs) and long-acting reversible contraception (LARC). From September 2012 to March 2015, 1168 FSWs sought services, including 587 (50%) who were HIV-positive. More than 90% had previously tested for HIV, and 26% who reported previously testing negative had seroconverted. Read More

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http://dx.doi.org/10.1177/0956462418817050DOI Listing
February 2019
1 Read

Screening for Sexually Transmitted Diseases.

Prim Care 2019 Mar 24;46(1):157-173. Epub 2018 Dec 24.

Residency in General Preventive Medicine and Public Health, Florida Department of Health, Palm Beach County, 800 Clematis, West Palm Beach, FL 33401, USA.

This article discusses sexually transmitted infections (STI) screening and focuses on reportable STIs. This includes gonorrhea, chlamydia, syphilis, and human immunodeficiency virus. Hepatitis B and C, trichomonas, and herpes are covered as well. Read More

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http://dx.doi.org/10.1016/j.pop.2018.10.013DOI Listing
March 2019
6 Reads

Ligand-Efficient Inhibitors of Trichomonas vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase.

ACS Infect Dis 2019 Mar 1;5(3):345-352. Epub 2019 Feb 1.

Department of Chemistry , Adelphi University , 1 South Avenue , Garden City , New York 11530 , United States.

Trichomoniasis is caused by the parasitic protozoan Trichomonas vaginalis and is the most prevalent, nonviral sexually transmitted disease. The parasite has shown increasing resistance to the current 5-nitroimidazole therapies indicating the need for new therapies with different mechanisms. T. Read More

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http://dx.doi.org/10.1021/acsinfecdis.8b00346DOI Listing
March 2019
1 Read

Accuracy of the BD MAX™ vaginal panel in the diagnosis of infectious vaginitis.

Eur J Clin Microbiol Infect Dis 2019 May 26;38(5):877-882. Epub 2019 Jan 26.

Servicio de Microbiología, Hospital Universitario de Álava, Instituto de Investigación Biosanitaria, BioAraba, Osakidetza-Servicio Vasco de Salud. c/ Francisco Leandro de Viana, s/n., 01009, Vitoria-Gasteiz, Álava, Spain.

The aim of this study was to evaluate the BD MAX™ vaginal panel in the diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis by comparing it with conventional methods: (i) combination of Hay criteria and presence of clue cells with predominant growth of Gardnerella vaginalis, (ii) yeast culture, and (iii) combination of culture, wet mount microscopic examination, and an alternative molecular assay. One thousand vaginal samples of women ≥ 14 years were analyzed; 5% of the samples belonged to pregnant women. 19. Read More

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http://dx.doi.org/10.1007/s10096-019-03480-8DOI Listing
May 2019
4 Reads

Therapeutic uses of metronidazole and its side effects: an update.

Eur Rev Med Pharmacol Sci 2019 Jan;23(1):397-401

Área Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Ex Hacienda, Pachuca de Soto Hidalgo, México.

Objective: Metronidazole is an antibiotic widely used in different medical conditions such as trichomoniasis, amoebiasis, and giardiasis among others. Its use has been associated with toxicity; however, it is not well characterized. In this review, we discuss the different therapeutic uses of metronidazole and its side effects in order to aid future investigation in this field. Read More

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http://dx.doi.org/10.26355/eurrev_201901_16788DOI Listing
January 2019
4 Reads

Is It Time to Stop Using Single-dose Oral Metronidazole for the Treatment of Trichomoniasis in Women?

Sex Transm Dis 2019 May;46(5):e57-e59

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA.

The 2015 Centers for Disease Control Sexually Transmitted Disease treatment guidelines currently recommend a single 2-g dose of oral metronidazole as the preferred regimen for treatment of trichomoniasis in human immunodeficiency virus (HIV)-negative women. Mounting recent evidence has shown that the 7-day oral metronidazole dosing regimen is more efficacious than the single 2-g dose. This commentary reviews the implications associated with these new data and discusses issues surrounding it that should be considered moving forward. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6465136PMC

Trichomonas Vaginalis Infection among Women Attending laboratory Centers in Ilam, Iran.

Infect Disord Drug Targets 2019 Jan 17. Epub 2019 Jan 17.

Department of Parasitology, school of medicine, Ilam University of Medical Sciences, Ilam. Iran.

Trichomoniasis is known as a common venereal disease. It is estimated that 180 million people in the world are infected with this disease. The present study was conducted to estimate the prevalence of (Trichomonas vaginalis) T. Read More

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http://www.eurekaselect.com/169077/article
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http://dx.doi.org/10.2174/1871526519666190117120705DOI Listing
January 2019
8 Reads

Hormonal Contraceptives and the Acquisition of Sexually Transmitted Infections: An Updated Systematic Review.

Sex Transm Dis 2019 May;46(5):290-296

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA.

Background: Evidence suggests that some forms of hormonal contraception (HC) increase women's risk of non-human immunodeficiency virus sexually transmitted infections (STIs), yet evidence has not been reviewed since 2008. We conducted an updated systematic review to incorporate studies published between January 2009 and June 2017 to examine the relationship between HCs and incident or recurrent STIs.

Methods: We searched PubMed and EMBASE to identify prospective studies comparing risk of Chlamydia trachomatis, Neisseria gonorrhoeae, human papillomavirus (HPV), herpes simplex virus type 2 (HSV-2), Treponema pallidum, or Trichomonas vaginalis, between women using HC versus nonhormonal methods or no methods. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000975DOI Listing
May 2019
2 Reads

Trichomonas vaginalis virus: a review of the literature.

Int J STD AIDS 2019 Apr 9;30(5):496-504. Epub 2019 Jan 9.

1 Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

Trichomonas vaginalis (TV) is a parasitic protozoan responsible for the sexually transmitted infection trichomoniasis. Trichomonas vaginalis virus (TVV) is a nonsegmented, 4.5-5 kbp, double-stranded RNA virus, from the Totiviridae family, which inhabits TV. Read More

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http://dx.doi.org/10.1177/0956462418809767DOI Listing
April 2019
1 Read

Retrospective Chart Analysis of Child and Adolescent Trichomonas vaginalis Infection in Houston, Texas.

J Pediatric Infect Dis Soc 2019 Jan 8. Epub 2019 Jan 8.

Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Background: Trichomonas vaginalis infection causes significant morbidity in the United States. Despite its high national disease burden, the epidemiologic characteristics of child and adolescent cases are not well understood. In this study, we aimed to describe the socioeconomic, transmission risk factors, clinical manifestations, and geospatial variables associated with cases of T vaginalis infection in the Houston, Texas, metropolitan area. Read More

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http://dx.doi.org/10.1093/jpids/piy134DOI Listing
January 2019

Trichomonas vaginalis and Mycoplasma hominis: new tales of two old friends.

Parasitology 2019 Jan 8:1-6. Epub 2019 Jan 8.

Department of Biomedical Sciences,University of Sassari,Sassari,Italy.

Trichomonas vaginalis is an anaerobic protist, responsible for the most prevalent non-viral sexually transmitted infection in humans. One of the most intriguing aspects of T. vaginalis pathobiology is the complex relationship with intracellular microbial symbionts: a group of dsRNA viruses belonging to family of Totiviridae (T. Read More

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http://dx.doi.org/10.1017/S0031182018002135DOI Listing
January 2019
3 Reads

Chemotherapeutic options for the treatment of human trichomoniasis.

Int J Antimicrob Agents 2019 Feb 27;53(2):116-127. Epub 2018 Oct 27.

Institute of Specific Prophylaxis and Tropical Medicine, Centre for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A-1090 Vienna, Austria. Electronic address:

Trichomonas vaginalis is the causative agent of the most common non-viral sexually transmitted disease worldwide. The infection may be associated with severe complications, including infertility, preterm labour, cancer and an increased risk of human immunodeficiency virus (HIV) transmission. Treatment remains almost exclusively based on 5-nitroimidazoles, but resistance is on the rise. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09248579183030
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http://dx.doi.org/10.1016/j.ijantimicag.2018.10.016DOI Listing
February 2019
3 Reads

Prevalence of Infectious Organisms Observed in Cervical Smears Between 1997-2014 at Mubarak Al-Kabeer Hospital, Kuwait.

Sultan Qaboos Univ Med J 2018 Aug 19;18(3):e324-e328. Epub 2018 Dec 19.

Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait.

Objectives: This study aimed to examine gynaecological infectious agents observed in conventional and modified Papanicolaou cervical smears (CS) at a tertiary care hospital in Kuwait.

Methods: This retrospective study analysed 121,443 satisfactory CS samples collected between 1997-2014 at the Mubarak Al-Kabeer Hospital, Kuwait. Conventional CS samples were obtained between 1997-2005, while modified CS were obtained between 2006-2014 following the introduction of ThinPrep testing (Hologic Corp. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307630PMC
August 2018
3 Reads

Prevalence, clinical features, and diagnosis of among female STI clinic attendees in Trinidad.

J Family Med Prim Care 2018 Sep-Oct;7(5):1054-1057

Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Background: (TV) is one of the most common pathogens causing sexually transmitted infections (STIs) in both men and women. Since there are no accurate prevalence data available on TV infection among women for Trinidad and Tobago and in the Caribbean region, there is a great need for research to study the dynamics of the infection and its transmission.

Objectives: To determine the prevalence and diagnose TV infection in women attending the STI clinic and to provide recommendations for control and prevention of trichomoniasis in the community. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_102_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259553PMC
January 2019
2 Reads

Antiparasitic activity of synthetic curcumin monocarbonyl analogues against Trichomonas vaginalis.

Biomed Pharmacother 2019 Mar 26;111:367-377. Epub 2018 Dec 26.

Laboratory of Lipidomics and Bioorganic, Bioforensics Research Group, Federal University of Pelotas, RS, 96010-900, Brazil.

Trichomoniasis is a parasitic infection caused by Trichomonas vaginalis and it is considered to be the most common non-viral sexually transmitted infection in the world. Since the 1960s, nitroimidazoles such as metronidazole are the drugs of choice for the treatment of trichomoniasis, but many adverse effects and allergic reactions may result from their use. Reports of metronidazole-resistant infections also highlight the importance for the search of new anti-T. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.12.058DOI Listing
March 2019
8 Reads

A novel 6-pyrophosphorylating IP6 kinase (IP6-6K) discovered in the protozoon Trichomonas vaginalis.

Mol Biochem Parasitol 2019 01 26;227:53-63. Epub 2018 Dec 26.

Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

The parasitic protozoon Trichomonas vaginalis is the pathogen of trichomoniasis, the most common non-viral, sexually transmitted disease in humans. Inositol phosphates function in the pathomechanisms of a number of human pathogenic protozoa. Recent findings point to a role of inositol phosphates in T. Read More

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http://dx.doi.org/10.1016/j.molbiopara.2018.12.004DOI Listing
January 2019
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Trichomonas vaginalis infection and the diagnostic significance of detection tests among Ghanaian outpatients.

BMC Womens Health 2018 12 27;18(1):206. Epub 2018 Dec 27.

Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Korle-bu, Accra, Ghana.

Background: There is little data on Trichomonas vaginalis infection in Ghana. This study evaluated the prevalence of trichomoniasis using different diagnostic methods and determined the risk factors for infection in patients.

Methods: A structured questionnaire was administered. Read More

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http://dx.doi.org/10.1186/s12905-018-0699-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307156PMC
December 2018
6 Reads
1.657 Impact Factor

Treatment recommendations for trichomoniasis in women.

Lancet Infect Dis 2019 Jan;19(1):20-21

Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1016/S1473-3099(18)30720-5DOI Listing
January 2019
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Trichomonicidal activity of a new anthraquinone isolated from the roots of Morinda panamensis Seem.

Drug Dev Res 2019 02 20;80(1):155-161. Epub 2018 Dec 20.

Posgrado de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico, D.F., Mexico.

Trichomoniasis, caused by the protozoan parasite Trichomonas vaginalis, is the most common nonviral sexually transmitted infection worldwide. Although drug treatment is available, unpleasant side effects and increased resistance to the nitroimidazole family have been documented. Hence, there is a need for the identification of new and safe therapeutic agents against T. Read More

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http://doi.wiley.com/10.1002/ddr.21504
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http://dx.doi.org/10.1002/ddr.21504DOI Listing
February 2019
22 Reads

Motility-based label-free detection of parasites in bodily fluids using holographic speckle analysis and deep learning.

Light Sci Appl 2018 12;7:108. Epub 2018 Dec 12.

1Electrical and Computer Engineering Department, University of California, Los Angeles, CA 90095 USA.

Parasitic infections constitute a major global public health issue. Existing screening methods that are based on manual microscopic examination often struggle to provide sufficient volumetric throughput and sensitivity to facilitate early diagnosis. Here, we demonstrate a motility-based label-free computational imaging platform to rapidly detect motile parasites in optically dense bodily fluids by utilizing the locomotion of the parasites as a specific biomarker and endogenous contrast mechanism. Read More

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http://dx.doi.org/10.1038/s41377-018-0110-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290798PMC
December 2018
6 Reads

Epinecidin-1: A marine fish antimicrobial peptide with therapeutic potential against Trichomonas vaginalis infection in mice.

Peptides 2019 Feb 12;112:139-148. Epub 2018 Dec 12.

Department and Graduate Institute of Aquaculture, National Kaohsiung University of Science and Technology, Kaohsiung 811, Taiwan. Electronic address:

Trichomoniasis is caused by infection with the protozoan parasite Trichomonas vaginalis, and prolonged persistence may lead to serious ill effects in patients. Thus, the development of new therapeutic strategies to combat drug-resistant T. vaginalis would be clinically beneficial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01969781183024
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http://dx.doi.org/10.1016/j.peptides.2018.12.004DOI Listing
February 2019
19 Reads

Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV/AIDS.

AIDS Rev 2018 ;20(4):187-204

Sexually Transmitted infections Unit, Centro Sanitario Sandoval. Madrid, Spain.

Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Read More

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http://www.aidsreviews.com/resumen.php?id=1448
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http://dx.doi.org/10.24875/AIDSRev.18000034DOI Listing
January 2018
21 Reads

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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http://dx.doi.org/10.1007/s12639-018-1043-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261132PMC
December 2018
17 Reads

The Protozoan Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases.

MBio 2018 12 11;9(6). Epub 2018 Dec 11.

School of Biological Sciences, University of Auckland, Auckland, New Zealand

The human eukaryotic pathogen causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota, but key aspects of the complex interactions between the parasite and the vaginal bacteria remain elusive. We report that has acquired, by lateral gene transfer from bacteria, genes encoding peptidoglycan hydrolases of the NlpC/P60 family. Read More

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http://mbio.asm.org/lookup/doi/10.1128/mBio.01784-18
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http://dx.doi.org/10.1128/mBio.01784-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299479PMC
December 2018
10 Reads