8,033 results match your criteria Trichomoniasis


Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study.

BMJ Open 2019 Feb 19;9(2):e026888. Epub 2019 Feb 19.

Centre for the AIDS Programme in South Africa (CAPRISA), Durban, South Africa.

Objectives: Syndromic management of sexually transmitted infections (STIs) omits asymptomatic infections, particularly among women. Accurate point-of-care assays may improve STI care in low- and middle-income countries (LMICs). We aimed to evaluate the diagnostic performance of the Xpert / (CT/NG) and OSOM (TV) Test as part of a STI care model for young women in South Africa. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02688
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http://dx.doi.org/10.1136/bmjopen-2018-026888DOI Listing
February 2019
2 Reads

Trichomonas vaginalis virus (TVV) among women with trichomoniasis and associations with demographics, clinical outcomes, and metronidazole resistance.

Clin Infect Dis 2019 Feb 15. Epub 2019 Feb 15.

Division of Infectious Diseases, University of Alabama at Birmingham.

Background: Trichomonas vaginalis virus (TVV) is a non-segmented, 4.5-5.5 kbp, double-stranded RNA virus infecting T. Read More

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http://dx.doi.org/10.1093/cid/ciz146DOI Listing
February 2019
1 Read

Does Male Circumcision Reduce Women's Risk of Sexually Transmitted Infections, Cervical Cancer, and Associated Conditions?

Front Public Health 2019 31;7. Epub 2019 Jan 31.

Department of Urology, University of Washington School of Medicine, Seattle, WA, United States.

Male circumcision (MC) is proven to substantially reduce men's risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to determine the relationship between MC and risk of STIs and associated conditions in women. Database searches by "circumcision women" and "circumcision female" identified 68 relevant articles for inclusion. Read More

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http://dx.doi.org/10.3389/fpubh.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365441PMC
January 2019
2 Reads

The prevalence of Mycoplasma genitalium and association with HIV infection in symptomatic patients, Johannesburg, South Africa, 2007-2014.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

Centre for HIV & STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.

Background: Mycoplasma genitalium is associated with genital discharge syndrome, but limited prevalence data is available in South Africa. The prevalence rates of M. genitalium infection and HIV co-infection were determined in urogenital specimens collected from male and female patients presenting with genital discharge syndrome to a primary health care centre in Johannesburg, South Africa from 2007 through 2014. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000984DOI Listing
February 2019
2 Reads

Acceptability and feasibility of sexually transmissible infection screening among pregnant women in Hanoi, Vietnam.

Sex Health 2019 Feb 11. Epub 2019 Feb 11.

Vietnam currently has no antenatal screening program for curable sexually transmissible infections (STIs). The aim of this study was to determine the prevalence of curable STIs, correlates of infections and assess the acceptability and feasibility of antenatal STI screening in Hanoi, Vietnam. A study involving 800 pregnant women visiting Ha Dong Hospital in Hanoi, Vietnam from June 2016 to July 2017, was conducted. Read More

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http://dx.doi.org/10.1071/SH18041DOI Listing
February 2019
1 Read

Female sex workers in Kigali, Rwanda: a key population at risk of HIV, sexually transmitted infections, and unplanned pregnancy.

Int J STD AIDS 2019 Feb 6:956462418817050. Epub 2019 Feb 6.

1 Projet San Francisco, Rwanda Zambia HIV Research Group, Kigali, Rwanda.

Female sex workers (FSWs) were recruited from known hotspots in Kigali, Rwanda, and offered free, anonymous human immunodeficiency virus (HIV) counseling and testing, diagnosis and treatment of sexually transmitted infections (STIs) and long-acting reversible contraception (LARC). From September 2012 to March 2015, 1168 FSWs sought services, including 587 (50%) who were HIV-positive. More than 90% had previously tested for HIV, and 26% who reported previously testing negative had seroconverted. Read More

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http://dx.doi.org/10.1177/0956462418817050DOI Listing
February 2019
1 Read

Screening for Sexually Transmitted Diseases.

Prim Care 2019 Mar 24;46(1):157-173. Epub 2018 Dec 24.

Residency in General Preventive Medicine and Public Health, Florida Department of Health, Palm Beach County, 800 Clematis, West Palm Beach, FL 33401, USA.

This article discusses sexually transmitted infections (STI) screening and focuses on reportable STIs. This includes gonorrhea, chlamydia, syphilis, and human immunodeficiency virus. Hepatitis B and C, trichomonas, and herpes are covered as well. Read More

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http://dx.doi.org/10.1016/j.pop.2018.10.013DOI Listing
March 2019
4 Reads

Ligand-Efficient Inhibitors of Trichomonas vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase.

ACS Infect Dis 2019 Feb 1. Epub 2019 Feb 1.

Department of Chemistry , Adelphi University , 1 South Avenue , Garden City , New York 11530 , United States.

Trichomoniasis is caused by the parasitic protozoan Trichomonas vaginalis and is the most prevalent, nonviral sexually transmitted disease. The parasite has shown increasing resistance to the current 5-nitroimidazole therapies indicating the need for new therapies with different mechanisms. T. Read More

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http://dx.doi.org/10.1021/acsinfecdis.8b00346DOI Listing
February 2019

Accuracy of the BD MAX™ vaginal panel in the diagnosis of infectious vaginitis.

Eur J Clin Microbiol Infect Dis 2019 Jan 26. Epub 2019 Jan 26.

Servicio de Microbiología, Hospital Universitario de Álava, Instituto de Investigación Biosanitaria, BioAraba, Osakidetza-Servicio Vasco de Salud. c/ Francisco Leandro de Viana, s/n., 01009, Vitoria-Gasteiz, Álava, Spain.

The aim of this study was to evaluate the BD MAX™ vaginal panel in the diagnosis of bacterial vaginosis (BV), vulvovaginal candidiasis (VVC), and trichomoniasis by comparing it with conventional methods: (i) combination of Hay criteria and presence of clue cells with predominant growth of Gardnerella vaginalis, (ii) yeast culture, and (iii) combination of culture, wet mount microscopic examination, and an alternative molecular assay. One thousand vaginal samples of women ≥ 14 years were analyzed; 5% of the samples belonged to pregnant women. 19. Read More

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http://dx.doi.org/10.1007/s10096-019-03480-8DOI Listing
January 2019
2 Reads

Therapeutic uses of metronidazole and its side effects: an update.

Eur Rev Med Pharmacol Sci 2019 Jan;23(1):397-401

Área Académica de Medicina, Instituto de Ciencias de la Salud, Universidad Autónoma del Estado de Hidalgo, Circuito Ex Hacienda, Pachuca de Soto Hidalgo, México.

Objective: Metronidazole is an antibiotic widely used in different medical conditions such as trichomoniasis, amoebiasis, and giardiasis among others. Its use has been associated with toxicity; however, it is not well characterized. In this review, we discuss the different therapeutic uses of metronidazole and its side effects in order to aid future investigation in this field. Read More

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http://dx.doi.org/10.26355/eurrev_201901_16788DOI Listing
January 2019
3 Reads

Is It Time to Stop Using Single Dose Oral Metronidazole for the Treatment of Trichomoniasis in Women?

Sex Transm Dis 2018 Dec 5. Epub 2018 Dec 5.

Tulane University School of Public Health and Tropical Medicine - Department of Epidemiology.

The 2015 Centers for Disease Control STD Treatment Guidelines currently recommend a single 2-gram dose of oral metronidazole (MTZ) as the preferred regimen for treatment of trichomoniasis in HIV-negative women. Mounting recent evidence has shown that the 7-day oral MTZ dosing regimen is more efficacious than the single 2-gram dose. This commentary reviews the implications associated with these new data and discusses issues surrounding it that should be considered moving forward. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000959DOI Listing
December 2018

Trichomonas Vaginalis Infection among Women Attending laboratory Centers in Ilam, Iran.

Infect Disord Drug Targets 2019 Jan 17. Epub 2019 Jan 17.

Department of Parasitology, school of medicine, Ilam University of Medical Sciences, Ilam. Iran.

Trichomoniasis is known as a common venereal disease. It is estimated that 180 million people in the world are infected with this disease. The present study was conducted to estimate the prevalence of (Trichomonas vaginalis) T. Read More

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http://www.eurekaselect.com/169077/article
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http://dx.doi.org/10.2174/1871526519666190117120705DOI Listing
January 2019
3 Reads

Hormonal contraceptives and the acquisition of sexually transmitted infections: an updated systematic review.

Sex Transm Dis 2019 Jan 8. Epub 2019 Jan 8.

City University of New York, Graduate School of Public Health & Health Policy, New York, USA.

Background: Evidence suggests that some forms of hormonal contraception (HC) increase women's risk of non-HIV sexually transmitted infections (STIs), yet evidence has not been reviewed since 2008. We conducted an updated systematic review to incorporate studies published between January 2009 and June 2017 to examine the relationship between HCs and incident and/or recurrent STIs.

Methods: We searched PubMed and EMBASE to identify prospective studies comparing risk of Chlamydia trachomatis, Neisseria gonorrhoeae, human papillomavirus (HPV), herpes simplex virus type 2 (HSV-2), Treponema pallidum, or Trichomonas vaginalis, between women using HC vs. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000975DOI Listing
January 2019
1 Read

Trichomonas vaginalis virus: a review of the literature.

Int J STD AIDS 2019 Jan 9:956462418809767. Epub 2019 Jan 9.

1 Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

Trichomonas vaginalis (TV) is a parasitic protozoan responsible for the sexually transmitted infection trichomoniasis. Trichomonas vaginalis virus (TVV) is a nonsegmented, 4.5-5 kbp, double-stranded RNA virus, from the Totiviridae family, which inhabits TV. Read More

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http://dx.doi.org/10.1177/0956462418809767DOI Listing
January 2019

Retrospective Chart Analysis of Child and Adolescent Trichomonas vaginalis Infection in Houston, Texas.

J Pediatric Infect Dis Soc 2019 Jan 8. Epub 2019 Jan 8.

Section of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

Background: Trichomonas vaginalis infection causes significant morbidity in the United States. Despite its high national disease burden, the epidemiologic characteristics of child and adolescent cases are not well understood. In this study, we aimed to describe the socioeconomic, transmission risk factors, clinical manifestations, and geospatial variables associated with cases of T vaginalis infection in the Houston, Texas, metropolitan area. Read More

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http://dx.doi.org/10.1093/jpids/piy134DOI Listing
January 2019

Trichomonas vaginalis and Mycoplasma hominis: new tales of two old friends.

Parasitology 2019 Jan 8:1-6. Epub 2019 Jan 8.

Department of Biomedical Sciences,University of Sassari,Sassari,Italy.

Trichomonas vaginalis is an anaerobic protist, responsible for the most prevalent non-viral sexually transmitted infection in humans. One of the most intriguing aspects of T. vaginalis pathobiology is the complex relationship with intracellular microbial symbionts: a group of dsRNA viruses belonging to family of Totiviridae (T. Read More

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http://dx.doi.org/10.1017/S0031182018002135DOI Listing
January 2019

Chemotherapeutic options for the treatment of human trichomoniasis.

Int J Antimicrob Agents 2019 Feb 27;53(2):116-127. Epub 2018 Oct 27.

Institute of Specific Prophylaxis and Tropical Medicine, Centre for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, A-1090 Vienna, Austria. Electronic address:

Trichomonas vaginalis is the causative agent of the most common non-viral sexually transmitted disease worldwide. The infection may be associated with severe complications, including infertility, preterm labour, cancer and an increased risk of human immunodeficiency virus (HIV) transmission. Treatment remains almost exclusively based on 5-nitroimidazoles, but resistance is on the rise. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09248579183030
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http://dx.doi.org/10.1016/j.ijantimicag.2018.10.016DOI Listing
February 2019
3 Reads

Prevalence, clinical features, and diagnosis of among female STI clinic attendees in Trinidad.

J Family Med Prim Care 2018 Sep-Oct;7(5):1054-1057

Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Background: (TV) is one of the most common pathogens causing sexually transmitted infections (STIs) in both men and women. Since there are no accurate prevalence data available on TV infection among women for Trinidad and Tobago and in the Caribbean region, there is a great need for research to study the dynamics of the infection and its transmission.

Objectives: To determine the prevalence and diagnose TV infection in women attending the STI clinic and to provide recommendations for control and prevention of trichomoniasis in the community. Read More

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http://dx.doi.org/10.4103/jfmpc.jfmpc_102_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6259553PMC
January 2019
2 Reads

Antiparasitic activity of synthetic curcumin monocarbonyl analogues against Trichomonas vaginalis.

Biomed Pharmacother 2018 Dec 26;111:367-377. Epub 2018 Dec 26.

Laboratory of Lipidomics and Bioorganic, Bioforensics Research Group, Federal University of Pelotas, RS, 96010-900, Brazil.

Trichomoniasis is a parasitic infection caused by Trichomonas vaginalis and it is considered to be the most common non-viral sexually transmitted infection in the world. Since the 1960s, nitroimidazoles such as metronidazole are the drugs of choice for the treatment of trichomoniasis, but many adverse effects and allergic reactions may result from their use. Reports of metronidazole-resistant infections also highlight the importance for the search of new anti-T. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.12.058DOI Listing
December 2018
5 Reads

A novel 6-pyrophosphorylating IP6 kinase (IP6-6K) discovered in the protozoon Trichomonas vaginalis.

Mol Biochem Parasitol 2019 Jan 26;227:53-63. Epub 2018 Dec 26.

Department of Biochemistry and Signal Transduction, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany.

The parasitic protozoon Trichomonas vaginalis is the pathogen of trichomoniasis, the most common non-viral, sexually transmitted disease in humans. Inositol phosphates function in the pathomechanisms of a number of human pathogenic protozoa. Recent findings point to a role of inositol phosphates in T. Read More

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http://dx.doi.org/10.1016/j.molbiopara.2018.12.004DOI Listing
January 2019

Trichomonas vaginalis infection and the diagnostic significance of detection tests among Ghanaian outpatients.

BMC Womens Health 2018 Dec 27;18(1):206. Epub 2018 Dec 27.

Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences, University of Ghana, Korle-bu, Accra, Ghana.

Background: There is little data on Trichomonas vaginalis infection in Ghana. This study evaluated the prevalence of trichomoniasis using different diagnostic methods and determined the risk factors for infection in patients.

Methods: A structured questionnaire was administered. Read More

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http://dx.doi.org/10.1186/s12905-018-0699-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307156PMC
December 2018
1 Read
1.657 Impact Factor

Treatment recommendations for trichomoniasis in women.

Lancet Infect Dis 2019 Jan;19(1):20-21

Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1016/S1473-3099(18)30720-5DOI Listing
January 2019
1 Read

Trichomonicidal activity of a new anthraquinone isolated from the roots of Morinda panamensis Seem.

Drug Dev Res 2019 Feb 20;80(1):155-161. Epub 2018 Dec 20.

Posgrado de Ciencias Genómicas, Universidad Autónoma de la Ciudad de México, Mexico, D.F., Mexico.

Trichomoniasis, caused by the protozoan parasite Trichomonas vaginalis, is the most common nonviral sexually transmitted infection worldwide. Although drug treatment is available, unpleasant side effects and increased resistance to the nitroimidazole family have been documented. Hence, there is a need for the identification of new and safe therapeutic agents against T. Read More

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http://doi.wiley.com/10.1002/ddr.21504
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http://dx.doi.org/10.1002/ddr.21504DOI Listing
February 2019
15 Reads

Motility-based label-free detection of parasites in bodily fluids using holographic speckle analysis and deep learning.

Light Sci Appl 2018 12;7:108. Epub 2018 Dec 12.

1Electrical and Computer Engineering Department, University of California, Los Angeles, CA 90095 USA.

Parasitic infections constitute a major global public health issue. Existing screening methods that are based on manual microscopic examination often struggle to provide sufficient volumetric throughput and sensitivity to facilitate early diagnosis. Here, we demonstrate a motility-based label-free computational imaging platform to rapidly detect motile parasites in optically dense bodily fluids by utilizing the locomotion of the parasites as a specific biomarker and endogenous contrast mechanism. Read More

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http://dx.doi.org/10.1038/s41377-018-0110-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290798PMC
December 2018
5 Reads

Epinecidin-1: A marine fish antimicrobial peptide with therapeutic potential against Trichomonas vaginalis infection in mice.

Peptides 2019 Feb 12;112:139-148. Epub 2018 Dec 12.

Department and Graduate Institute of Aquaculture, National Kaohsiung University of Science and Technology, Kaohsiung 811, Taiwan. Electronic address:

Trichomoniasis is caused by infection with the protozoan parasite Trichomonas vaginalis, and prolonged persistence may lead to serious ill effects in patients. Thus, the development of new therapeutic strategies to combat drug-resistant T. vaginalis would be clinically beneficial. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01969781183024
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http://dx.doi.org/10.1016/j.peptides.2018.12.004DOI Listing
February 2019
13 Reads

Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV/AIDS.

AIDS Rev 2018 ;20(4):187-204

Sexually Transmitted infections Unit, Centro Sanitario Sandoval. Madrid, Spain.

Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Read More

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http://www.aidsreviews.com/resumen.php?id=1448
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http://dx.doi.org/10.24875/AIDSRev.18000034DOI Listing
January 2018
14 Reads

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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http://dx.doi.org/10.1007/s12639-018-1043-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261132PMC
December 2018
16 Reads

The Protozoan Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases.

MBio 2018 12 11;9(6). Epub 2018 Dec 11.

School of Biological Sciences, University of Auckland, Auckland, New Zealand

The human eukaryotic pathogen causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota, but key aspects of the complex interactions between the parasite and the vaginal bacteria remain elusive. We report that has acquired, by lateral gene transfer from bacteria, genes encoding peptidoglycan hydrolases of the NlpC/P60 family. Read More

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http://mbio.asm.org/lookup/doi/10.1128/mBio.01784-18
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http://dx.doi.org/10.1128/mBio.01784-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299479PMC
December 2018
7 Reads

Anti-Trichomonas vaginalis activity of chalcone and amino-analogues.

Parasitol Res 2019 Feb 7;118(2):607-615. Epub 2018 Dec 7.

Laboratório de Pesquisa em Parasitologia, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, RS, 90610-000, Brazil.

Trichomoniasis is the most common non-viral sexually transmitted disease worldwide and can lead to serious consequences in reproductive health, cancer, and HIV acquisition. The current approved treatment present adverse effects and drug resistance data on this neglected parasitic infection is underestimated. Chalcones are a family of molecules that present biological applications, such as activity against many pathogenic organisms including protozoan pathogens. Read More

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http://link.springer.com/10.1007/s00436-018-6164-4
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http://dx.doi.org/10.1007/s00436-018-6164-4DOI Listing
February 2019
6 Reads

Understanding the burden of bacterial sexually transmitted infections and Trichomonas vaginalis among black Caribbeans in the United Kingdom: Findings from a systematic review.

PLoS One 2018 7;13(12):e0208315. Epub 2018 Dec 7.

Institute for Global Health, University College London, London, United Kingdom.

Background: In the UK, people of black Caribbean (BC) ethnicity continue to be disproportionately affected by bacterial sexually transmitted infections (STIs) and Trichomonas vaginalis (TV). We systematically reviewed evidence on the association between bacterial STIs/TV and ethnicity (BC compared to white/white British (WB)) accounting for other risk factors; and differences between these two ethnic groups in the prevalence of risk factors associated with these STIs, sexual healthcare seeking behaviours, and contextual factors influencing STI risk.

Methods: Studies presenting relevant evidence for participants aged ≥14 years and living in the UK were eligible for inclusion. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208315PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6285827PMC
December 2018

Contraceptive use and the risk of sexually transmitted infection: systematic review and current perspectives.

Open Access J Contracept 2018 12;9:91-112. Epub 2018 Nov 12.

Global Health, Population and Nutrition, FHI 360, Durham, NC, USA,

Purpose: Evidence on the association between contraceptive use and risk of sexually transmitted infections (STIs) and bacterial vaginosis (BV) is lacking, with few prospective studies. We systematically reviewed the last 10 years' evidence on the association between contraception and STI/BV, building on the most recent systematic reviews published in 2006 and 2009.

Methods: We searched the MEDLINE and POPLINE databases for peer-reviewed articles p ublished between January 1, 2008 and January 31, 2018 reporting prospective studies that assessed the association between contraceptive use and incident STI and/or incident or recurrent BV. Read More

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http://dx.doi.org/10.2147/OAJC.S135439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239113PMC
November 2018
14 Reads

New treatment recommendations for trichomoniasis in women.

Lancet Infect Dis 2018 Dec;18(12):1307-1308

National Center for Sexually Transmitted Disease Control, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Dermatology, Nanjing 210042, China. Electronic address:

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http://dx.doi.org/10.1016/S1473-3099(18)30666-2DOI Listing
December 2018

Comparative effect of manuka honey on anaerobic parasitic protozoans with standard drug therapy under conditions: A preliminary study.

Indian J Pharmacol 2018 Jul-Aug;50(4):197-203

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: From the past five decades, metronidazole and tinidazole have been used for treating nonresistant and resistant giardiasis and trichomoniasis. However, due to the occurrence of drug resistance to standard therapy idealizes us to explore some additional therapies which is cost-effective, easy accessibility, and natural which has least side effects. Manuka honey obtained from is well known for its antibacterial and wound healing properties and is thought to be a better option as an additional therapy. Read More

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http://dx.doi.org/10.4103/ijp.IJP_227_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234710PMC
December 2018
1 Read
0.679 Impact Factor

Etiology of Vaginal/Cervical Discharge Syndrome: Analysis of Data from a Referral Laboratory in Eastern India.

Indian J Dermatol 2018 Nov-Dec;63(6):484-489

Department of VD Serology and Department of STD, Institute of Serology, Kolkata, West Bengal, India.

Context: Sexually transmitted infections (STIs) and reproductive tract infections (RTIs) constitute important public health problem worldwide. Syndromic diagnosis of vaginal/cervical discharge (VCD) is often inaccurate leading to over- or under-treatment.

Aims: This study aimed to ascertain the laboratory-confirmed diagnosis of VCD and their relative frequency in a group of patients presenting to a STI clinic in eastern India and to determine the sensitivity and specificity of clinical diagnosis. Read More

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http://dx.doi.org/10.4103/ijd.IJD_296_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233047PMC
December 2018
2 Reads

Sexual risk behaviour in a cohort of HIV-negative and HIV-positive Rwandan women.

Epidemiol Infect 2018 Dec 3:1-9. Epub 2018 Dec 3.

Department of Pharmacology,University of Gothenburg,Gothenburg,Sweden.

Here we wanted to assess whether sexual risk behaviour differs dependent by human immunodeficiency virus (HIV) status by following 100 HIV- and 137 HIV+ women recruited at two university teaching hospitals in Rwanda. Women were tested for sexually transmitted infections (STIs; trichomoniasis, syphilis, hepatitis B and C) and for reproductive tract infections (RTIs; candidiasis, bacterial vaginosis (BV)) and were interviewed at baseline and 9 months later. BV was the most prevalent infection, while syphilis was the most common STI with a 9-month incidence of 10. Read More

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http://dx.doi.org/10.1017/S0950268818003023DOI Listing
December 2018
3 Reads

Incidence and predictors of reinfection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients.

Int J STD AIDS 2018 Nov 28:956462418807115. Epub 2018 Nov 28.

1 Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

Trichomonas vaginalis infection contributes to HIV transmission. The study objective was to determine the incidence and predictors of T. vaginalis reinfection among HIV-infected women in Birmingham, Alabama. Read More

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http://dx.doi.org/10.1177/0956462418807115DOI Listing
November 2018

Reaching key populations through key venues: Insights from the Jamaica HIV Prevention Program.

PLoS One 2018 26;13(11):e0206962. Epub 2018 Nov 26.

Department of Medicine, University of North Carolina, North Carolina, United States of America.

Introduction: HIV prevention strategies often include outreach to female sex workers at social venues identified as places where people meet new sexual partners. Patrons and staff at these venues may include female sex workers, their clients, as well as others who have high rates of new sexual partnerships. Few studies have compared HIV/STI among venue-based and general populations, across types of venues, or by sub-group of the venue population. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206962PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261031PMC
November 2018
10 Reads

A retrospective epidemiological analysis of shared risk factors for bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina).

Prev Vet Med 2018 Dec 29;161:109-114. Epub 2018 Oct 29.

Department of Animal Production, School of Veterinary, University of Cordoba, 14071, Spain.

The venereal diseases bovine trichomoniasis (BT) and bovine genital campylobacteriosis (BGC) cause economic losses in endemic areas like La Pampa province in Argentina, where beef cattle are usually managed extensively. The eradication of both diseases is a priority in Argentine. The aim of this case-control study was to identify shared and specific risk factors of both diseases from the data obtained from the Provincial Program for the Control and Eradication of BT and BGC in La Pampa (PCE). Read More

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http://dx.doi.org/10.1016/j.prevetmed.2018.10.022DOI Listing
December 2018
7 Reads

Calophyllum inophyllum in vaginitis treatment: Stimulated by electroporation with an in vitro approach.

Adv Clin Exp Med 2018 Nov 22. Epub 2018 Nov 22.

Department of Molecular and Cellular Biology, Faculty of Pharmacy with Division of Laboratory Diagnostics, Wroclaw Medical University, Poland.

Background: Vaginitis is one of the most common problems in clinical medicine and is cited most often during visits to obstetricians and gynecologists. Most of the inflammation cases are caused by candidiasis trichomoniasis and bacterial vaginosis. Therefore, treatment of vaginal infections must use antibiotic or antifungal drugs, which often provide quick relief to the patient. Read More

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http://dx.doi.org/10.17219/acem/87045DOI Listing
November 2018
12 Reads

WHO laboratory validation of Xpert CT/NG and Xpert TV on the GeneXpert system verifies high performances.

APMIS 2018 Dec;126(12):907-912

WHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Effective tests for diagnosis of sexually transmitted infections (STIs), used point of care to inform treatment and management decisions, are urgently needed. We evaluated the analytical sensitivity and specificity of the Xpert CT/NG and Xpert TV tests, examining 339 samples spiked with phenotypically and/or genetically diverse strains of Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis, and other related species that may cross-react. The APTIMA Combo 2 test and APTIMA TV test were used as reference tests. Read More

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http://doi.wiley.com/10.1111/apm.12902
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http://dx.doi.org/10.1111/apm.12902DOI Listing
December 2018
7 Reads

Synthesis and modification of crystalline SBA-15 nanowhiskers as a pH-sensitive metronidazole nanocarrier system.

Int J Pharm 2019 Jan 15;555:28-35. Epub 2018 Nov 15.

Young Researchers and Elite Club, Urmia Branch, Islamic Azad University, Urmia, Iran; Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

Clinical resistance to drugs and diminution in their side effects have become great issues for pharmacologists. In veterinary medicine, parasites like Trichomonas gallinae are of veterinary, hygienic and economic importance and can be treated by metronidazole. Unfortunately, scientific evidence has been reported about its resistance and serious side effects in trichomoniasis. Read More

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http://dx.doi.org/10.1016/j.ijpharm.2018.11.034DOI Listing
January 2019
2 Reads

Transmission electron microscopy revealing the mechanism of action of photodynamic therapy on Trichomonas vaginalis.

Acta Trop 2019 Feb 14;190:112-118. Epub 2018 Nov 14.

Faculty of Pharmacy, Universidade de Itaúna, Rodovia MG 431 Km 45, s/n, Itaúna, Brazil. Electronic address:

Trichomonas vaginalis is an amitochondrial parasite that causes human trichomoniasis. Despite metronidazole effectiveness, resistant cases are becoming more frequent. This scenario reveals the need to develop new therapeutic options. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0001706X183105
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http://dx.doi.org/10.1016/j.actatropica.2018.11.005DOI Listing
February 2019
10 Reads

Associations between county-level voter turnout, county-level felony voter disenfranchisement, and sexually transmitted infections among women in the Southern United States.

Ann Epidemiol 2019 Jan 29;29:67-73.e1. Epub 2018 Oct 29.

Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and Department of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Purpose: Voting may play a critical role in the allocation of social and structural resources to communities, which in turn shapes neighborhood environments, and ultimately, an individual's sexually transmitted infection (STI) risk. We assessed relationships among county-level voter turnout and felony voter disenfranchisement, and STIs.

Methods: This cross-sectional multilevel analysis included 666 women in Alabama, Florida, Georgia, Mississippi, and North Carolina enrolled in the Women's Interagency HIV Study between 2013 and 2015. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10472797183026
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http://dx.doi.org/10.1016/j.annepidem.2018.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344302PMC
January 2019
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Trichomonas vaginalis triggers the release of THP-1 extracellular traps.

Parasitol Res 2019 Jan 13;118(1):267-274. Epub 2018 Nov 13.

Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.

Trichomonas vaginalis is responsible for the prevalence of trichomoniasis, which may be one of the most epidemic nonviral sexually transmitted pathogens. Extracellular traps (ET) are a unique form of innate immunity against infection; they bind to and kill microorganisms. However, the effect of T. Read More

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http://dx.doi.org/10.1007/s00436-018-6139-5DOI Listing
January 2019
3 Reads

Highly Potent 1-1,2,3-Triazole-Tethered Isatin-Metronidazole Conjugates Against Anaerobic Foodborne, Waterborne, and Sexually-Transmitted Protozoal Parasites.

Front Cell Infect Microbiol 2018 30;8:380. Epub 2018 Oct 30.

Department of Chemistry, Guru Nanak Dev University, Amritsar, India.

Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in tropical and subtropical regions of the world. Metronidazole (MTZ) is the current drug of choice for amebiasis, giardiasis, and trichomoniasis but it has several adverse effects and potential resistance is a concern. In order to develop alternative antimicrobials, a library of 1-1,2,3-triazole-tethered metronidazole-isatin conjugates was synthesized using Huisgen's azide-alkyne cycloaddition reaction and evaluated for their amebicidal, anti-trichomonal, and anti-giardial potential. Read More

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https://www.frontiersin.org/article/10.3389/fcimb.2018.00380
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http://dx.doi.org/10.3389/fcimb.2018.00380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218680PMC
October 2018
6 Reads

Risk of sexually transmitted infections following depressive disorder: A nationwide population-based cohort study.

Medicine (Baltimore) 2018 Oct;97(43):e12539

Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi.

Depressive disorder is a severe mental disorder associated with functional and cognitive impairment. Numerous papers in the literature investigated associations between sexually transmitted infections (STIs) and psychiatric illnesses. However, the results of these studies are controversial. Read More

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http://dx.doi.org/10.1097/MD.0000000000012539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221703PMC
October 2018
5 Reads

Urogenital pathogens, associated with Trichomonas vaginalis, among pregnant women in Kilifi, Kenya: a nested case-control study.

BMC Infect Dis 2018 Nov 6;18(1):549. Epub 2018 Nov 6.

Laboratory Bacteriology Research, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan, 185, Ghent, Belgium.

Background: Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with similar urogenital syndromes, remain undiagnosed and/or untreated. Some of these pathogens are associated with adverse pregnancy outcomes.

Methods: In a nested case-control study, vaginal swabs from 79 pregnant women, i. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3455-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219184PMC
November 2018
19 Reads

Home Self-Collection by Mail to Test for Human Papillomavirus and Sexually Transmitted Infections.

Obstet Gynecol 2018 Dec;132(6):1412-1420

Departments of Epidemiology and Health Behavior, Gillings School of Global Public Health, the School of Medicine, and the Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina; Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China; the Department of Biological and Biomedical Sciences, College of Arts and Science, North Carolina Central University, Durham, North Carolina; and the American Sexual Health Association, Durham, North Carolina.

Objective: To evaluate the validity and acceptability of at-home self-collection to test for high-risk human papillomavirus (HPV) and sexually transmitted infections among women overdue for cervical cancer screening by national guidelines.

Methods: Low-income, infrequently screened women were recruited from the general population in North Carolina to participate in an observational study. Participants provided two self-collected cervicovaginal samples (one at home and one in the clinic) and a clinician-collected cervical sample. Read More

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http://Insights.ovid.com/crossref?an=00006250-900000000-9787
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http://dx.doi.org/10.1097/AOG.0000000000002964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249061PMC
December 2018
8 Reads

Acceptability and efficacy of partner notification for curable sexually transmitted infections in sub-Saharan Africa: A systematic review.

Int J STD AIDS 2018 Nov 5:956462418803983. Epub 2018 Nov 5.

1 Department of Infectious Disease, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Comprehensive case management of sexually transmitted infections (STIs) includes partner notification. We reviewed the recent literature evaluating the acceptability and efficacy of partner notification strategies (i.e. Read More

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http://dx.doi.org/10.1177/0956462418803983DOI Listing
November 2018
6 Reads