8,003 results match your criteria Trichomoniasis


Epinecidin-1: A marine fish antimicrobial peptide with therapeutic potential against Trichomonas vaginalis infection in mice.

Peptides 2018 Dec 12. Epub 2018 Dec 12.

Department and Graduate Institute of Aquaculture, National Kaohsiung University of Science and Technology, Kaohsiung 811, Taiwan. Electronic address:

Trichomoniasis is caused by infection with the protozoan parasite Trichomonas vaginalis, and prolonged persistence may lead to serious ill effects in patients. Thus, the development of new therapeutic strategies to combat drug-resistant T. vaginalis would be clinically beneficial. Read More

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December 2018
2 Reads

Rebound in Sexually Transmitted Infections Following the Success of Antiretrovirals for HIV/AIDS.

AIDS Rev 2018 ;20(4):187-204

Sexually Transmitted infections Unit, Centro Sanitario Sandoval. Madrid, Spain.

Nearly 1 million people become infected every day with any of the four major curable sexually transmitted infections (STIs), namely trichomoniasis, chlamydia, gonorrhea, and syphilis. Despite huge global incidence, STIs remain as neglected diseases. The success of antiretrovirals for halting progression to AIDS in HIV-infected individuals and for stopping HIV transmission to uninfected contacts, either as pre- or post-exposure -prophylaxis, has to lead to increased risky sexual behaviors through risk compensation. Read More

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January 2018

Spectrum of parasitic infections in centrifuged urine sediments from a newly developed tertiary care centre in Central India.

J Parasit Dis 2018 Dec 29;42(4):608-615. Epub 2018 Oct 29.

3Department of Microbiology, All India Institute of Medical Sciences, Saket Nagar, Bhopal, MP 462024 India.

Detection of urinary parasites is relatively rare and incidental finding in routine urine examination. Common urinary parasitic infections as described in literature include Trichomonas, and Microfilaria. is known to cause vaginitis and urethritis, and may be found in urine sediments. Read More

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December 2018

The Protozoan Targets Bacteria with Laterally Acquired NlpC/P60 Peptidoglycan Hydrolases.

MBio 2018 Dec 11;9(6). Epub 2018 Dec 11.

School of Biological Sciences, University of Auckland, Auckland, New Zealand

The human eukaryotic pathogen causes trichomoniasis, a prevalent sexually transmitted infection. This extracellular protozoan is intimately associated with the human vaginal mucosa and microbiota, but key aspects of the complex interactions between the parasite and the vaginal bacteria remain elusive. We report that has acquired, by lateral gene transfer from bacteria, genes encoding peptidoglycan hydrolases of the NlpC/P60 family. Read More

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December 2018
1 Read

Anti-Trichomonas vaginalis activity of chalcone and amino-analogues.

Parasitol Res 2018 Dec 7. Epub 2018 Dec 7.

Laboratório de Pesquisa em Parasitologia, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, RS, 90610-000, Brazil.

Trichomoniasis is the most common non-viral sexually transmitted disease worldwide and can lead to serious consequences in reproductive health, cancer, and HIV acquisition. The current approved treatment present adverse effects and drug resistance data on this neglected parasitic infection is underestimated. Chalcones are a family of molecules that present biological applications, such as activity against many pathogenic organisms including protozoan pathogens. Read More

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December 2018
1 Read

Understanding the burden of bacterial sexually transmitted infections and Trichomonas vaginalis among black Caribbeans in the United Kingdom: Findings from a systematic review.

PLoS One 2018 7;13(12):e0208315. Epub 2018 Dec 7.

Institute for Global Health, University College London, London, United Kingdom.

Background: In the UK, people of black Caribbean (BC) ethnicity continue to be disproportionately affected by bacterial sexually transmitted infections (STIs) and Trichomonas vaginalis (TV). We systematically reviewed evidence on the association between bacterial STIs/TV and ethnicity (BC compared to white/white British (WB)) accounting for other risk factors; and differences between these two ethnic groups in the prevalence of risk factors associated with these STIs, sexual healthcare seeking behaviours, and contextual factors influencing STI risk.

Methods: Studies presenting relevant evidence for participants aged ≥14 years and living in the UK were eligible for inclusion. Read More

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December 2018

Contraceptive use and the risk of sexually transmitted infection: systematic review and current perspectives.

Open Access J Contracept 2018 12;9:91-112. Epub 2018 Nov 12.

Global Health, Population and Nutrition, FHI 360, Durham, NC, USA,

Purpose: Evidence on the association between contraceptive use and risk of sexually transmitted infections (STIs) and bacterial vaginosis (BV) is lacking, with few prospective studies. We systematically reviewed the last 10 years' evidence on the association between contraception and STI/BV, building on the most recent systematic reviews published in 2006 and 2009.

Methods: We searched the MEDLINE and POPLINE databases for peer-reviewed articles p ublished between January 1, 2008 and January 31, 2018 reporting prospective studies that assessed the association between contraceptive use and incident STI and/or incident or recurrent BV. Read More

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November 2018
2 Reads

New treatment recommendations for trichomoniasis in women.

Lancet Infect Dis 2018 Dec;18(12):1307-1308

National Center for Sexually Transmitted Disease Control, Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Dermatology, Nanjing 210042, China. Electronic address:

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December 2018

Comparative effect of manuka honey on anaerobic parasitic protozoans with standard drug therapy under conditions: A preliminary study.

Indian J Pharmacol 2018 Jul-Aug;50(4):197-203

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Background: From the past five decades, metronidazole and tinidazole have been used for treating nonresistant and resistant giardiasis and trichomoniasis. However, due to the occurrence of drug resistance to standard therapy idealizes us to explore some additional therapies which is cost-effective, easy accessibility, and natural which has least side effects. Manuka honey obtained from is well known for its antibacterial and wound healing properties and is thought to be a better option as an additional therapy. Read More

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December 2018

Etiology of Vaginal/Cervical Discharge Syndrome: Analysis of Data from a Referral Laboratory in Eastern India.

Indian J Dermatol 2018 Nov-Dec;63(6):484-489

Department of VD Serology and Department of STD, Institute of Serology, Kolkata, West Bengal, India.

Context: Sexually transmitted infections (STIs) and reproductive tract infections (RTIs) constitute important public health problem worldwide. Syndromic diagnosis of vaginal/cervical discharge (VCD) is often inaccurate leading to over- or under-treatment.

Aims: This study aimed to ascertain the laboratory-confirmed diagnosis of VCD and their relative frequency in a group of patients presenting to a STI clinic in eastern India and to determine the sensitivity and specificity of clinical diagnosis. Read More

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December 2018
2 Reads

Sexual risk behaviour in a cohort of HIV-negative and HIV-positive Rwandan women.

Epidemiol Infect 2018 Dec 3:1-9. Epub 2018 Dec 3.

Department of Pharmacology,University of Gothenburg,Gothenburg,Sweden.

Here we wanted to assess whether sexual risk behaviour differs dependent by human immunodeficiency virus (HIV) status by following 100 HIV- and 137 HIV+ women recruited at two university teaching hospitals in Rwanda. Women were tested for sexually transmitted infections (STIs; trichomoniasis, syphilis, hepatitis B and C) and for reproductive tract infections (RTIs; candidiasis, bacterial vaginosis (BV)) and were interviewed at baseline and 9 months later. BV was the most prevalent infection, while syphilis was the most common STI with a 9-month incidence of 10. Read More

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December 2018
2 Reads

Incidence and predictors of reinfection with trichomoniasis based on nucleic acid amplification testing results in HIV-infected patients.

Int J STD AIDS 2018 Nov 28:956462418807115. Epub 2018 Nov 28.

1 Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.

Trichomonas vaginalis infection contributes to HIV transmission. The study objective was to determine the incidence and predictors of T. vaginalis reinfection among HIV-infected women in Birmingham, Alabama. Read More

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November 2018

Reaching key populations through key venues: Insights from the Jamaica HIV Prevention Program.

PLoS One 2018 26;13(11):e0206962. Epub 2018 Nov 26.

Department of Medicine, University of North Carolina, North Carolina, United States of America.

Introduction: HIV prevention strategies often include outreach to female sex workers at social venues identified as places where people meet new sexual partners. Patrons and staff at these venues may include female sex workers, their clients, as well as others who have high rates of new sexual partnerships. Few studies have compared HIV/STI among venue-based and general populations, across types of venues, or by sub-group of the venue population. Read More

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November 2018
6 Reads

A retrospective epidemiological analysis of shared risk factors for bovine trichomoniasis and bovine genital campylobacteriosis in La Pampa province (Argentina).

Prev Vet Med 2018 Dec 29;161:109-114. Epub 2018 Oct 29.

Department of Animal Production, School of Veterinary, University of Cordoba, 14071, Spain.

The venereal diseases bovine trichomoniasis (BT) and bovine genital campylobacteriosis (BGC) cause economic losses in endemic areas like La Pampa province in Argentina, where beef cattle are usually managed extensively. The eradication of both diseases is a priority in Argentine. The aim of this case-control study was to identify shared and specific risk factors of both diseases from the data obtained from the Provincial Program for the Control and Eradication of BT and BGC in La Pampa (PCE). Read More

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December 2018
1 Read

Calophyllum inophyllum in vaginitis treatment: Stimulated by electroporation with an in vitro approach.

Adv Clin Exp Med 2018 Nov 22. Epub 2018 Nov 22.

Department of Molecular and Cellular Biology, Faculty of Pharmacy with Division of Laboratory Diagnostics, Wroclaw Medical University, Poland.

Background: Vaginitis is one of the most common problems in clinical medicine and is cited most often during visits to obstetricians and gynecologists. Most of the inflammation cases are caused by candidiasis trichomoniasis and bacterial vaginosis. Therefore, treatment of vaginal infections must use antibiotic or antifungal drugs, which often provide quick relief to the patient. Read More

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November 2018
5 Reads

WHO laboratory validation of Xpert CT/NG and Xpert TV on the GeneXpert system verifies high performances.

APMIS 2018 Dec;126(12):907-912

WHO Collaborating Centre for Gonorrhoea and Other Sexually Transmitted Infections, National Reference Laboratory for Sexually Transmitted Infections, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Effective tests for diagnosis of sexually transmitted infections (STIs), used point of care to inform treatment and management decisions, are urgently needed. We evaluated the analytical sensitivity and specificity of the Xpert CT/NG and Xpert TV tests, examining 339 samples spiked with phenotypically and/or genetically diverse strains of Neisseria gonorrhoeae, Chlamydia trachomatis, and Trichomonas vaginalis, and other related species that may cross-react. The APTIMA Combo 2 test and APTIMA TV test were used as reference tests. Read More

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December 2018
2 Reads

Synthesis and modification of crystalline SBA-15 nanowhiskers as a pH-sensitive metronidazole nanocarrier system.

Int J Pharm 2018 Nov 15;555:28-35. Epub 2018 Nov 15.

Young Researchers and Elite Club, Urmia Branch, Islamic Azad University, Urmia, Iran; Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

Clinical resistance to drugs and diminution in their side effects have become great issues for pharmacologists. In veterinary medicine, parasites like Trichomonas gallinae are of veterinary, hygienic and economic importance and can be treated by metronidazole. Unfortunately, scientific evidence has been reported about its resistance and serious side effects in trichomoniasis. Read More

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November 2018

Transmission electron microscopy revealing the mechanism of action of photodynamic therapy on Trichomonas vaginalis.

Acta Trop 2018 Nov 14;190:112-118. Epub 2018 Nov 14.

Faculty of Pharmacy, Universidade de Itaúna, Rodovia MG 431 Km 45, s/n, Itaúna, Brazil. Electronic address:

Trichomonas vaginalis is an amitochondrial parasite that causes human trichomoniasis. Despite metronidazole effectiveness, resistant cases are becoming more frequent. This scenario reveals the need to develop new therapeutic options. Read More

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November 2018
5 Reads

Associations between county-level voter turnout, county-level felony voter disenfranchisement, and sexually transmitted infections among women in the Southern United States.

Ann Epidemiol 2018 Oct 29. Epub 2018 Oct 29.

Institute for Global Health and Infectious Diseases, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA and Department of Health Sciences, Bouvé College of Health Sciences, Northeastern University, Boston, MA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.

Purpose: Voting may play a critical role in the allocation of social and structural resources to communities, which in turn shapes neighborhood environments, and ultimately, an individual's sexually transmitted infection (STI) risk. We assessed relationships among county-level voter turnout and felony voter disenfranchisement, and STIs.

Methods: This cross-sectional multilevel analysis included 666 women in Alabama, Florida, Georgia, Mississippi, and North Carolina enrolled in the Women's Interagency HIV Study between 2013 and 2015. Read More

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October 2018
4 Reads

Trichomonas vaginalis triggers the release of THP-1 extracellular traps.

Parasitol Res 2018 Nov 13. Epub 2018 Nov 13.

Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, 130062, China.

Trichomonas vaginalis is responsible for the prevalence of trichomoniasis, which may be one of the most epidemic nonviral sexually transmitted pathogens. Extracellular traps (ET) are a unique form of innate immunity against infection; they bind to and kill microorganisms. However, the effect of T. Read More

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November 2018
1 Read

Highly Potent 1-1,2,3-Triazole-Tethered Isatin-Metronidazole Conjugates Against Anaerobic Foodborne, Waterborne, and Sexually-Transmitted Protozoal Parasites.

Front Cell Infect Microbiol 2018 30;8:380. Epub 2018 Oct 30.

Department of Chemistry, Guru Nanak Dev University, Amritsar, India.

Parasitic infections like amebiasis, trichomoniasis, and giardiasis are major health threats in tropical and subtropical regions of the world. Metronidazole (MTZ) is the current drug of choice for amebiasis, giardiasis, and trichomoniasis but it has several adverse effects and potential resistance is a concern. In order to develop alternative antimicrobials, a library of 1-1,2,3-triazole-tethered metronidazole-isatin conjugates was synthesized using Huisgen's azide-alkyne cycloaddition reaction and evaluated for their amebicidal, anti-trichomonal, and anti-giardial potential. Read More

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October 2018
3 Reads

Risk of sexually transmitted infections following depressive disorder: A nationwide population-based cohort study.

Medicine (Baltimore) 2018 Oct;97(43):e12539

Department of Psychiatry, Chiayi Branch, Taichung Veterans General Hospital, Chiayi.

Depressive disorder is a severe mental disorder associated with functional and cognitive impairment. Numerous papers in the literature investigated associations between sexually transmitted infections (STIs) and psychiatric illnesses. However, the results of these studies are controversial. Read More

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October 2018
5 Reads

Urogenital pathogens, associated with Trichomonas vaginalis, among pregnant women in Kilifi, Kenya: a nested case-control study.

BMC Infect Dis 2018 Nov 6;18(1):549. Epub 2018 Nov 6.

Laboratory Bacteriology Research, Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan, 185, Ghent, Belgium.

Background: Screening of curable sexually transmitted infections is frequently oriented towards the diagnosis of chlamydia, gonorrhea, syphilis and trichomoniasis, whereas other pathogens, sometimes associated with similar urogenital syndromes, remain undiagnosed and/or untreated. Some of these pathogens are associated with adverse pregnancy outcomes.

Methods: In a nested case-control study, vaginal swabs from 79 pregnant women, i. Read More

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November 2018
10 Reads

Home Self-Collection by Mail to Test for Human Papillomavirus and Sexually Transmitted Infections.

Obstet Gynecol 2018 Dec;132(6):1412-1420

Departments of Epidemiology and Health Behavior, Gillings School of Global Public Health, the School of Medicine, and the Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina; Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China; the Department of Biological and Biomedical Sciences, College of Arts and Science, North Carolina Central University, Durham, North Carolina; and the American Sexual Health Association, Durham, North Carolina.

Objective: To evaluate the validity and acceptability of at-home self-collection to test for high-risk human papillomavirus (HPV) and sexually transmitted infections among women overdue for cervical cancer screening by national guidelines.

Methods: Low-income, infrequently screened women were recruited from the general population in North Carolina to participate in an observational study. Participants provided two self-collected cervicovaginal samples (one at home and one in the clinic) and a clinician-collected cervical sample. Read More

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December 2018
4 Reads

Acceptability and efficacy of partner notification for curable sexually transmitted infections in sub-Saharan Africa: A systematic review.

Int J STD AIDS 2018 Nov 5:956462418803983. Epub 2018 Nov 5.

1 Department of Infectious Disease, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

Comprehensive case management of sexually transmitted infections (STIs) includes partner notification. We reviewed the recent literature evaluating the acceptability and efficacy of partner notification strategies (i.e. Read More

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November 2018
2 Reads

Trichomonas vaginalis Induces NLRP3 Inflammasome Activation and Pyroptotic Cell Death in Human Macrophages.

J Innate Immun 2018 Nov 2:1-13. Epub 2018 Nov 2.

Division of Host-Microbe Systems and Therapeutics, Department of Pediatrics, University of California, San Diego, La Jolla, California,

Trichomonas vaginalis is a sexually transmitted, eukaryotic parasite that causes trichomoniasis, the most common nonviral, sexually transmitted disease in the USA and worldwide. Little is known about the molecular mechanisms involved in the host immune response to this widespread parasite. Here we report that T. Read More

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November 2018
5 Reads

Longitudinal association of gonorrhea and bacterial vaginosis with repeat chlamydia diagnoses among U.S. Army women: a retrospective cohort analysis.

Mil Med Res 2018 10 30;5(1):37. Epub 2018 Oct 30.

Armed Forces Health Surveillance Branch, Public Health Division, Defense Health Agency, Silver Spring, MD, USA.

Background: Historically, sexually transmitted infections have affected the health of the U.S. military. Read More

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October 2018
6 Reads

PROVISION OF STI SERVICES IN A MOBILE CLINIC REVEALS HIGH UNMET NEED IN REMOTE AREAS OF SOUTH AFRICA: A CROSS-SECTIONAL STUDY.

Sex Transm Dis 2018 Oct 22. Epub 2018 Oct 22.

Anova Health Institute, Johannesburg, South Africa.

Background: The burden of sexually transmitted infections (STIs) in areas of sub-Saharan Africa with poor access to healthcare services is not well documented. In remote areas of South Africa we investigated the prevalence of STIs and approaches to providing STI services through a mobile clinic.

Methods: We recruited 251 adult women visiting a mobile clinic that normally provides general health education and screening services, but not STI care. Read More

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October 2018
5 Reads

Mycoplasma genitalium Infections in Women Attending a Sexually Transmitted Disease Clinic in New Orleans.

Clin Infect Dis 2018 Oct 23. Epub 2018 Oct 23.

Department of Medicine, Section of Infectious Diseases, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, USA.

Background: Several studies have reported statistically significant associations of Mycoplasma genitalium with cervicitis, urethritis, or vaginal discharge, although non-significant associations have also been reported. This study examined the associations of M. genitalium with selected sexually transmitted infections (STIs), demographic, behavioral, and clinical factors among women attending a sexually transmitted disease (STD) clinic in New Orleans. Read More

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October 2018
1 Read

Elevated Serum Cytokines and Trichomonas vaginalis Serology at Diagnosis Are Not Associated With Higher Gleason Grade or Lethal Prostate Cancer.

Clin Genitourin Cancer 2018 Oct 4. Epub 2018 Oct 4.

Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA. Electronic address:

Background: Inflammation and infections have been associated with prostate cancer progression. We assessed whether elevated serum cytokines or T. vaginalis seropositivity at the time of diagnosis was associated with higher grade or lethal prostate cancer. Read More

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October 2018
8 Reads

and HIV infection acquisition: a systematic review and meta-analysis.

Sex Transm Infect 2018 Oct 19. Epub 2018 Oct 19.

HIV/STI Reference Laboratory, Department of Clinical Sciences, Institute of Tropical Medicine, Antwerpen, Belgium.

Objectives: Trichomoniasis is the most prevalent curable STI globally, with the highest incidence and prevalence in sub-Saharan Africa (sSA). STIs have largely been associated with an increase in HIV acquisition. Our objective was to assess the existing literature available in English regarding the association of Trichomoniasis and HIV-1 acquisition. Read More

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October 2018
4 Reads

Analysis of Sexually Transmitted Diseases Within the Patient Population at a Student-Run Free Clinic.

J Am Osteopath Assoc 2018 Oct;118(10):e86-e91

Context: Uninsured patients living in rural areas of North Carolina have been inordinately affected by the increasing prevalence of sexually transmitted diseases (STDs) in the midst of severe budget cuts to treatment programs and a shortage of rural primary care physicians. The Campbell University Community Care Clinic, a self-funded, student-run clinic, provides free health care to uninsured residents of rural Harnett County. As a relatively new clinic serving a unique population, epidemiologic research is paramount to the clinic's continued efficacy. Read More

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October 2018
3 Reads

[Sexually Transmitted Infections in the Tropics].

Authors:
C Bendick

Hautarzt 2018 Nov;69(11):945-959

Department of Dermatology, Preah Kossamak-Hospital, BP 1006, Phnom Penh, Kambodscha.

Sexually transmitted infections (STI) are common all over the world and the incidence of chlamydia, gonorrhea, syphilis and trichomoniasis alone is estimated at 500 million/year. Of these infections 75% occur in tropical countries in Latin America, sub-Saharan Africa and South as well as Southeast Asia. The bacterial infections chancroid, lymphogranuloma venereum (LGV) and granuloma inguinale (GI, Donovanosis) are termed tropical STI. Read More

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November 2018
7 Reads

Will an innovative connected AideSmart! app-based multiplex, point-of-care screening strategy for HIV and related coinfections affect timely quality antenatal screening of rural Indian women? Results from a cross-sectional study in India.

Sex Transm Infect 2018 Oct 15. Epub 2018 Oct 15.

Rural Unit for Health and Social Affairs (RUHSA), Christian Medical College, Vellore, Tamil Nadu, India.

Objectives: In rural pregnant Indian women, multiple missed antenatal screening opportunities due to inadequate public health facility-based screening result in undiagnosed HIV and sexually transmitted bloodborne infections (STBBIs) and conditions (anaemia). Untreated infections complicate pregnancy management, precipitate adverse outcomes and risk mother-to-child transmission. Additionally, a shortage of trained doctors, rural women's preference for home delivery and health illiteracy affect health service delivery. Read More

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October 2018
4 Reads

Single-dose versus 7-day-dose metronidazole for the treatment of trichomoniasis in women: an open-label, randomised controlled trial.

Lancet Infect Dis 2018 Nov 5;18(11):1251-1259. Epub 2018 Oct 5.

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA; Section of Infectious Diseases, Louisiana State University Health Sciences Center, New Orleans, LA, USA.

Background: Among women, trichomoniasis is the most common non-viral sexually transmitted infection worldwide, and is associated with serious reproductive morbidity, poor birth outcomes, and amplified HIV transmission. Single-dose metronidazole is the first-line treatment for trichomoniasis. However, bacterial vaginosis can alter treatment efficacy in HIV-infected women, and single-dose metronidazole treatment might not always clear infection. Read More

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November 2018
6 Reads

The need for new treatment recommendations for trichomoniasis among women.

Lancet Infect Dis 2018 Nov 5;18(11):1168-1169. Epub 2018 Oct 5.

Division of Infectious Diseases, Department of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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November 2018
5 Reads

A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts.

BMC Infect Dis 2018 Oct 3;18(1):499. Epub 2018 Oct 3.

Perinatal HIV Research Unit (PHRU), Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Background: Youth in southern Africa, particularly adolescent girls and young women, are a key population for HIV prevention interventions. Untreated genital tract infections (GTIs) increase both HIV transmission and acquisition risks. South African GTI treatment guidelines employ syndromic management, which relies on individuals to report GTI signs and symptoms. Read More

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October 2018
1 Read

Molecular identification of Trichomonas tenax in the oral environment of domesticated animals in Poland - potential effects of host diversity for human health.

Ann Agric Environ Med 2018 Sep 12;25(3):464-468. Epub 2018 Jul 12.

Department of Medical Biology, Medical University of Warsaw, Warsaw, Poland.

Introduction: The protozoan Trichomonas tenax is considered to be a human specific flagellate of the oral cavity, found in humans with poor oral hygiene and advanced periodontal disease. Morphological variability and great similarity between species occurring in humans and animals, complicate the specific identification of trichomonads, using microscopic examination and other standard parasitological techniques.

Objective: The aim of the study was to search for and identify T. Read More

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September 2018
1 Read

The Additive Value of Pelvic Examinations to History in Predicting Sexually Transmitted Infections for Young Female Patients With Suspected Cervicitis or Pelvic Inflammatory Disease.

Ann Emerg Med 2018 Dec 2;72(6):703-712.e1. Epub 2018 Jul 2.

Department of Emergency Medicine, Newark Beth Israel Medical Center, Newark, NJ; Children's Hospital of New Jersey, Newark, NJ. Electronic address:

Study Objective: We evaluate the additive value of pelvic examinations in predicting sexually transmitted infection for young female patients with suspected cervicitis or pelvic inflammatory disease in a pediatric emergency department (ED).

Methods: This was a prospective observational study of female patients aged 14 to 20 years who presented to an urban academic pediatric ED with a complaint of vaginal discharge or lower abdominal pain. Enrolled patients provided a urine sample for chlamydia, gonorrhea, and trichomonas testing, which served as the criterion standard for diagnosis. Read More

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December 2018
1 Read

Prevalence and treatment of sexually transmitted infections in men followed by urologists in Germany - a cross sectional study with 347,090 men.

Ger Med Sci 2018 13;16:Doc03. Epub 2018 Aug 13.

Epidemiology, QuintilesIMS, Frankfurt, Germany.

The goal of this retrospective analysis was to study the prevalence and treatment of the most common sexually transmitted infections (STI) in men followed by urologists in Germany. This study included a total of 347,090 men followed in 71 urology practices in Germany between 2013 and 2015. The first outcome was the prevalence of individuals diagnosed with STI between 2013 and 2015. Read More

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August 2018
2 Reads

ACOG Committee Opinion No. 754: The Utility of and Indications for Routine Pelvic Examination.

Authors:

Obstet Gynecol 2018 Oct;132(4):e174-e180

The pelvic examination has long been considered a fundamental component of the well-woman visit, and many women and gynecologic care providers view this visit as an opportunity to discuss sexual and reproductive health issues. Traditionally, a pelvic examination is performed for asymptomatic women as a screening tool for gynecologic cancer, infection, and asymptomatic pelvic inflammatory disease; some obstetrician-gynecologists and patients consider it important in detecting subclinical disease, despite evidence to the contrary. Given changes in screening recommendations and the ability to screen for sexually transmitted infections using less-invasive methods, reevaluation of the role of the pelvic examination for asymptomatic, nonpregnant women is warranted. Read More

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October 2018
2 Reads

ACOG Committee Opinion No. 754 Summary: The Utility of and Indications for Routine Pelvic Examination.

Authors:

Obstet Gynecol 2018 Oct;132(4):1080-1083

The pelvic examination has long been considered a fundamental component of the well-woman visit, and many women and gynecologic care providers view this visit as an opportunity to discuss sexual and reproductive health issues. Traditionally, a pelvic examination is performed for asymptomatic women as a screening tool for gynecologic cancer, infection, and asymptomatic pelvic inflammatory disease; some obstetrician-gynecologists and patients consider it important in detecting subclinical disease, despite evidence to the contrary. Given changes in screening recommendations and the ability to screen for sexually transmitted infections using less-invasive methods, reevaluation of the role of the pelvic examination for asymptomatic, nonpregnant women is warranted. Read More

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October 2018
1 Read

Educational Case: Infectious Diseases: Pathogenesis, Diagnosis, Treatment, and Prevention.

Acad Pathol 2018 Jan-Dec;5:2374289518794191. Epub 2018 Sep 14.

Montefiore Hospital and Medical Center, Bronx, NY, USA.

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals. Read More

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September 2018
1 Read

Association between Trichomonas vaginalis and prostate cancer mortality.

Int J Cancer 2018 Sep 22. Epub 2018 Sep 22.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.

We previously observed a positive association between seropositivity for the parasite Trichomonas vaginalis and risk of clinically significant prostate cancer at diagnosis. Here, we examined whether T. vaginalis seropositivity was associated with increased prostate cancer-specific or all-cause mortality among prostate cancer patients. Read More

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September 2018
3 Reads

Prevalence of Haemoproteus columbae (Apicomplexa: Haemoproteidae) and Trichomonas gallinae (Metamonada: Trichomonadidae) Infections Among Pigeons (Columba livia) in West Azerbaijan Province, Iran.

Arch Razi Inst 2018 Jun 1;73(2):147-152. Epub 2018 Mar 1.

Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

A cross-sectional survey was performed on domestic pigeons (Columba liviadomestica) to evaluate the prevalence of Haemoproteus columbae and Trichomonas gallinae in West Azerbaijan Province, northwest of Iran between July 2015 and September 2016. Five hundred and sixty oropharyngeal swab smears were examined, 297 (53%) of which were identified to be positive for T. gallinae. Read More

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June 2018
2 Reads

Association between unhygienic menstrual management practices and prevalence of lower reproductive tract infections: a hospital-based cross-sectional study in Odisha, India.

BMC Infect Dis 2018 Sep 21;18(1):473. Epub 2018 Sep 21.

School of Life Sciences, AIPH University, Bhubaneswar, Odisha, India.

Background: The extent to which reproductive tract infections (RTIs) are associated with poor menstrual hygiene management (MHM) practices has not been extensively studied. We aimed to determine whether poor menstrual hygiene practices were associated with three common infections of the lower reproductive tract; Bacterial vaginosis (BV), Candida, and Trichomonas vaginalis (TV).

Methods: Non-pregnant women of reproductive age (18-45 years) and attending one of two hospitals in Odisha, India, between April 2015 and February 2016 were recruited for the study. Read More

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September 2018
3 Reads

In-Depth Quantitative Proteomic Analysis of Trophozoites and Pseudocysts of Trichomonas vaginalis.

J Proteome Res 2018 Nov 3;17(11):3704-3718. Epub 2018 Oct 3.

Departamento de Medicina , Universidade Federal de São João del Rei , 36301-160 São João del Rei , Minas Gerais Brazil.

Trichomonas vaginalis is a sexually transmitted anaerobic parasite that infects humans causing trichomoniasis, a common and ubiquitous sexually transmitted disease. The life cycle of this parasite possesses a trophozoite form without a cystic stage. However, the presence of nonproliferative and nonmotile, yet viable and reversible spherical forms with internalized flagella, denominated pseudocysts, has been commonly observed for this parasite. Read More

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November 2018
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The UALE project: a cross-sectional approach for trends in HIV/STI prevalence among key populations attending STI clinics in Guatemala.

BMJ Open 2018 Sep 19;8(9):e022632. Epub 2018 Sep 19.

Fundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.

Objective: To describe and compare trends in prevalence, sexual behaviour and HIV transmission knowledge data related to sexually transmitted infections (STI) and HIV in patients attending three STI clinics over an 8-year period in Escuintla Department, Guatemala.

Methods: STI clinic attendees were classified into transmission groups as follows: female sex workers (FSW), men who have sex with men (MSM) and 'high-risk heterosexuals' (HRH). Annual cross-sectional analysis and multivariable Poisson regression adjusted for sociodemographic variables were used for prevalence comparisons and adjusted prevalence trends for HIV/STI outcomes and used for adjusted trends in proportions in sexual behaviour and HIV transmission knowledge outcomes. Read More

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September 2018
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Sexually transmitted infections during pregnancy and subsequent risk of stillbirth and infant mortality in Kenya: a prospective study.

Sex Transm Infect 2018 Sep 18. Epub 2018 Sep 18.

Department of Global Health, University of Washington, Seattle, Washington, USA

Objectives: We evaluated the relationship of sexually transmitted infections (STIs) and genital infections during pregnancy and subsequent risk for infant mortality and stillbirth.

Methods: This was a nested longitudinal analysis using data from a study of peripartum HIV acquisition in Kenya. In the parent study, HIV-uninfected women were enrolled during pregnancy and followed until 9 months postpartum. Read More

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September 2018
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