5,100 results match your criteria Trichinosis


Differentiation of Trichinella species (Trichinella spiralis/Trichinella britovi versus Trichinella pseudospiralis) using western blot.

Parasit Vectors 2018 Dec 12;11(1):631. Epub 2018 Dec 12.

European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, viale Regina Elena 299, 00161, Rome, Italy.

Background: Trichinellosis is a meat-borne zoonotic disease caused by parasites of the genus Trichinella. To date, 12 taxa have been described. The identification of Trichinella species is crucial in order to identify the possible source of infection, the geographical origin of the parasite and to assess risk of infection for domestic pigs and humans. Read More

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December 2018

Oral vaccination with Trichinella spiralis DNase II DNA vaccine delivered by attenuated Salmonella induces a protective immunity in BALB/c mice.

Vet Res 2018 Dec 5;49(1):119. Epub 2018 Dec 5.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

Trichinellosis is one of the most serious foodborne parasitic zoonosis with worldwide distribution, and it is necessary to develop a vaccine to interrupt transmission from animals to humans. Trichinella spiralis adult-specific DNase II-1 (TsDNase II) were identified by immunoproteomics in surface or excretory/secretory proteins of adult worms (AW) and intestinal infective larvae (IIL). The aim of this study was to investigate the systemic, mucosal responses and immune protection elicited by oral vaccination with TsDNase II DNA vaccine delivered by attenuated Salmonella typhimurium strain⊿cyaSL1344. Read More

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December 2018
1 Read
2.815 Impact Factor

Wild Boar: A Reservoir of Foodborne Zoonoses.

Foodborne Pathog Dis 2018 Nov 27. Epub 2018 Nov 27.

Department of Food Hygiene and Environmental Health, Faculty of Veterinary Medicine, University of Helsinki , Helsinki, Finland .

Wild boar populations around the world have increased dramatically over past decades. Climate change, generating milder winters with less snow, may affect their spread into northern regions. Wild boars can serve as reservoirs for a number of bacteria, viruses, and parasites, which are transmissible to humans and domestic animals through direct interaction with wild boars, through contaminated food or indirectly through contaminated environment. Read More

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November 2018
5 Reads

Characterization of Two Adult-Specific DNase II and Their Capacity to Induce Protective Immunity.

Front Microbiol 2018 5;9:2504. Epub 2018 Nov 5.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, China.

Deoxyribonuclease II (DNase II) is a widespread endonuclease, which can degrade the DNA. adult-specific DNase II-1 (TsDNase II-1) and DNase II-7 (TsDNase II-7) were identified in excretory-secretory (ES) or surface proteins of adult worm (AW) and intestinal infective larvae (IIL) using immunoproteomics with early infection sera. The aim of this study was to characterize the two DNase II enzymes and to investigate their role as potential vaccine candidate target molecules. Read More

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November 2018

Trichinella britovi muscle larvae and adult worms: stage-specific and common antigens detected by two-dimensional gel electrophoresis-based immunoblotting.

Parasit Vectors 2018 Nov 12;11(1):584. Epub 2018 Nov 12.

Witold Stefański Institute of Parasitology, Polish Academy of Sciences, Twarda 51/55, 00-818, Warsaw, Poland.

Background: Trichinella britovi is the second most common species of Trichinella that may affect human health. As an early diagnosis of trichinellosis is crucial for effective treatment, it is important to identify sensitive, specific and common antigens of adult T. britovi worms and muscle larvae. Read More

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November 2018
4 Reads

Trichinella spiralis prevalence among wildlife of a boreal region rapidly reduced in the absence of spillover from the domestic cycle.

Vet Parasitol 2018 Oct 9;262:1-5. Epub 2018 Sep 9.

European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

Carnivore and omnivore animals are the main reservoir hosts of nematodes of the genus Trichinella. Out of the twelve taxa identified so far in the world, four, namely Trichinella spiralis, Trichinella nativa, Trichinella britovi and Trichinella pseudospiralis, are circulating in Europe. All these four species were detected in Finnish wild animals and T. Read More

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October 2018
1 Read
2.460 Impact Factor

Multiplex TaqMan qPCR assay for specific identification of encapsulated Trichinella species prevalent in North America.

Mem Inst Oswaldo Cruz 2018 Oct 29;113(11):e180305. Epub 2018 Oct 29.

US Food and Drug Administration Center for Food Safety and Applied Nutrition, Office of Applied Nutrition and Safety Assessment, Laurel, MD, USA.

BACKGROUND Human trichinellosis is a foodborne parasitic zoonotic disease caused by ingestion of raw or undercooked meat infected with nematode larvae of the genus Trichinella. In the USA, sporadic cases and outbreaks caused by the consumption of wild game meat infected with Trichinella have been reported. The current methods for diagnosis such as serology and microscopy are not specific, may result in false negative results, and cannot differentiate encapsulated Trichinella larvae to species level. Read More

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October 2018
9 Reads

Killing the muscular larvae of Trichinella spiralis and the anti-fibrotic effect of the combination of Wortmannilatone F and recombinant G31P in a murine model of trichinellosis.

Biomed Pharmacother 2018 Dec 27;108:934-940. Epub 2018 Sep 27.

Department of Parasitology, Basic Medical College, Dalian Medical University, Dalian, 116044, Liaoning, China. Electronic address:

Although trichinosis is one of the global food-borne parasitic diseases and is considered an emerging/re-emerging disease that has been reported in 66 countries, the drugs for its prevention and treatment have not been thoroughly investigated. Wortmannilactone F (WF) has been reported as a blocker of the helminth mitochondria respiratory chain by inhibiting NADH-fumarate reductase in the mitochondrial inner membrane. CXCL8 (3-73) K11R/G31 P(G31 P) has been reported as a CXCL8 analogue that has the affinity to CXCR1 and CXCR2. Read More

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December 2018
1 Read

A Tricky Diagnosis.

N Engl J Med 2018 Oct;379(14):1364-1369

From the Departments of Emergency Medicine (A.S., B.F., B.P.) and Laboratory Medicine and Pathology (V.N.), Alameda Health System-Highland Hospital, Oakland, and the Department of Emergency Medicine and Division of Infectious Diseases, Olive View-UCLA Medical Center, Sylmar (D.A.T.) - both in California.

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October 2018
3 Reads

Use of ELISA and Western blot for serological detection of antibodies to E-S antigens of Trichinella spiralis muscle larvae in sera of swine experimentally infected with Trichinella spiralis.

Vet Immunol Immunopathol 2018 Sep 29;203:13-20. Epub 2018 Jul 29.

Department of Food Hygiene of Animal Origin, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Akademicka 12, 20-950 Lublin, Poland.

The aim of the present study was to evaluate the detection of trichinellosis using ELISA, and to determine the degree of variation of IgG antibodies against excretory-secretory (E-S) antigens of T. spiralis muscle larvae. Ten young Polish Large White native breed pigs were experimentally inoculated with a low dose of 300 invasive Trichinella spiralis (T. Read More

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September 2018
1 Read

Protective immunity against Trichinella spiralis in mice elicited by oral vaccination with attenuated Salmonella-delivered TsSP1.2 DNA.

Vet Res 2018 Sep 6;49(1):87. Epub 2018 Sep 6.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

Trichinellosis is a worldwide important food-borne zoonosis caused mainly by ingesting raw or undercooked pork infected with Trichinella spiralis larvae. The development of vaccine is needed for preventing swine from Trichinella infection to ensure pork safety. Previous studies showed that T. Read More

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September 2018
6 Reads
2.820 Impact Factor

Vaccination with DNA encoding ES 43-kDa /45-kDa antigens significantly reduces Trichinella spiralis infection in mice.

Res Vet Sci 2018 Oct 23;120:4-10. Epub 2018 Aug 23.

College of Animal Science and Technology and Jilin Provincial Engineering Research Center of Animal probiotics, Jilin Agricultural University, 2888 Xincheng Street, Changchun, Jilin 130118, China. Electronic address:

Trichinella spiralis is an intestinal nematode parasite that can cause trichinellosis in humans and animals worldwide. The most important known hosts of T. spiralis are pigs, horses, dogs and cats. Read More

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October 2018
15 Reads

No evidence of Trichinella spp. in domestic pig carcasses at a selected abattoir in southern Botswana.

Trop Anim Health Prod 2018 Aug 13. Epub 2018 Aug 13.

Department of Biomedical Sciences, School of Veterinary Medicine, Faculty of Agriculture and Natural Resources, University of Namibia, P. Bag 13301, Pioneerspark, Windhoek, Namibia.

Trichinellosis is a worldwide zoonosis with genotypes affecting different domestic and wild animals and is widely distributed throughout the world. Species and genotypes of this genus affecting different animals have been identified. Despite its occurrence in Sub-Saharan countries, the presence of trichinellosis in Botswana is yet to be confirmed. Read More

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Molecular characterization of Trichinella spiralis galectin and its participation in larval invasion of host's intestinal epithelial cells.

Vet Res 2018 08 2;49(1):79. Epub 2018 Aug 2.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

The aim of this study was to study the molecular characteristics of Trichinella spiralis galectin (Tsgal) and interactions between Tsgal and host's intestinal epithelial cells (IECs). The functional domain of Tsgal was cloned and expressed in an E. coli system. Read More

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August 2018
4 Reads

Outbreak of Trichinella T9 Infections Associated with Consumption of Bear Meat, Japan.

Emerg Infect Dis 2018 Aug;24(8):1532-1535

An outbreak of trichinellosis occurred in Japan in December 2016. All case-patients had eaten undercooked bear meat, from which Trichinella larvae were subsequently isolated. DNA sequencing analysis of the mitochondrial genes cytochrome c-oxidase subunit 1 and internal transcribed spacer 2 confirmed that Trichinella T9 had caused the outbreak. Read More

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August 2018
6 Reads

Molecular characterization of a putative serine protease from Trichinella spiralis and its elicited immune protection.

Vet Res 2018 07 13;49(1):59. Epub 2018 Jul 13.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

In our previous work, a Trichinella spiralis putative serine protease (TsSP) was identified from ES products of T. spiralis intestinal infective larvae (IIL) and adult worms (AW) by immunoproteomics: it was highly expressed in IIL compared with muscle larvae (ML). In this study, the TsSP biological characteristics in larval invasion and growth were identified and its potential as a vaccine target against Trichinella infection were investigated. Read More

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July 2018
3 Reads

Trichinella britovi in Game Meat Linked to Human Trichinellosis Outbreak in Serbia.

J Parasitol 2018 Oct 16;104(5):557-559. Epub 2018 Jul 16.

2   University of Belgrade, Faculty of Veterinary Medicine, Department of Food Hygiene and Technology, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia.

After a human trichinellosis outbreak in Zlatibor District, Serbia, in 2016, Trichinella larvae were found in wild boar ( Sus scrofa) meat products. One hundred and fourteen people were infected during the outbreak. The larvae were determined to be Trichinella britovi using the polymerase chain reaction method. Read More

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October 2018
15 Reads

Epizootic and Epidemiological Situation of sp. Infection in Poland in 2006-2015 in View of Wild Boar Population Dynamics.

J Vet Res 2017 Jun 6;61(2):181-187. Epub 2017 Dec 6.

Department of Zoology, Ecology and Wildlife Management, Lublin, Poland.

Introduction: The objective was to evaluate the epizootic and epidemiological situation of sp. infection in Poland between 2006 and 2015 against the dynamics of the wild boar population and its primary reservoir host.

Material And Methods: Boar and porcine trichinosis epizootic analysis was based on General Veterinary Inspectorate data from RRW-6 bulletins. Read More

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Multilocus genotype analysis outlines distinct histories for Trichinella britovi in the neighboring Mediterranean islands of Corsica and Sardinia.

Parasit Vectors 2018 Jun 19;11(1):353. Epub 2018 Jun 19.

European Union Reference Laboratory for Parasites, Istituto Superiore di Sanità, Rome, Italy.

Background: The zoonotic nematode Trichinella britovi was discovered in two neighboring Mediterranean islands of Corsica and Sardinia, almost simultaneously at the beginning of the 21st century. An epidemiological link between the two parasite populations was generally assumed. In 2015, an outbreak of trichinellosis in Nice, the South of France, was reportedly caused by the consumption of raw pork delicatessen imported from Corsica. Read More

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June 2018
2 Reads

Immunochromatographic test for rapid serological diagnosis of human angiostrongyliasis.

Int J Infect Dis 2018 Aug 13;73:69-71. Epub 2018 Jun 13.

Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia.

Objectives: The serological diagnosis of human infection with Angiostrongylus cantonensis remains problematic because there are no commercially available validated tests. Most laboratories use domestically prepared tests such as the enzyme-linked immunosorbent assay (ELISA) or immunoblotting. Since laboratory facilities are not always available in endemic areas, we developed and assessed a rapid lateral flow immunochromatographic assay (AcQuick Test) to detect anti-A. Read More

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August 2018
2 Reads

Cloning, expression and characterisation of a cysteine protease from Trichinella spiralis.

Folia Parasitol (Praha) 2018 May 29;65. Epub 2018 May 29.

Department of Parasitology, Medical College, Zhengzhou University, PR China.

Cysteine protease is a superfamily of widespread proteolytic enzymes and plays a major role in larval invasion, migration, exsheathing, survival and immune evasion in parasites. In the present study, the gene coding cysteine proteinase of the nematode Trichinella spiralis (Owen, 1835) was cloned into pQE-80L and subsequently expressed in E. coli JM109. Read More

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May 2018
10 Reads

Vaccines against Trichinella spiralis: Progress, challenges and future prospects.

Transbound Emerg Dis 2018 Dec 6;65(6):1447-1458. Epub 2018 Jun 6.

State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, China.

Trichinella spiralis, the causative agent of trichinellosis, is able to infect a wide range of carnivores and omnivores including human beings. In the past 30 years, a mass of vaccination efforts has been performed to control T. spiralis infection with the purpose of reduction in worm fecundity or decrease in muscle larval and adult burdens. Read More

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December 2018
7 Reads

Proteomic analysis of the response of Trichinella spiralis muscle larvae to exogenous nitric oxide.

PLoS One 2018 5;13(6):e0198205. Epub 2018 Jun 5.

Department of Microbiology and Parasitology, Anhui Key Laboratory of Infection and Immunity, Bengbu Medical College, Bengbu, China.

Trichinella spiralis mainly dwells in the muscle tissue of its host and is the main causative agent of trichinellosis in humans. Nitric oxide (NO), an important intracellular signaling molecule that may restrict pathogen growth in infected hosts, has been known for its anti-pathogenic activity, including resistance to T. spiralis. Read More

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December 2018
9 Reads

The impact of anthelminthic therapeutics on serological and tissues apoptotic changes induced by experimental trichinosis.

J Parasit Dis 2018 Jun 26;42(2):232-242. Epub 2018 Mar 26.

Medical Parasitology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Trichinosis is a sharable parasitic disease caused by spp., the disease occurred on eating inappropriate cooked pork infected by the parasite encysted larvae. This study aimed to evaluate experimentally the impact of treatment by thiabendazole, praziquantel (PZQ) and prednisone on induced parasitological, serological and apoptotic changes. Read More

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June 2018
1 Read

Ts-Hsp70 induces protective immunity against Trichinella spiralis infection in mouse by activating dendritic cells through TLR2 and TLR4.

PLoS Negl Trop Dis 2018 05 18;12(5):e0006502. Epub 2018 May 18.

Department of Medical Microbiology and Parasitology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.

Background: Trichinellosis is a serious food-borne parasitic zoonosis worldwide. In the effort to develop vaccine against Trichinella infection, we have identified Trichinella spiralis Heat shock protein 70 (Ts-Hsp70) elicits partial protective immunity against T. spiralis infection via activating dendritic cells (DCs) in our previous study. Read More

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May 2018
12 Reads

Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool.

PLoS Negl Trop Dis 2018 05 14;12(5):e0006485. Epub 2018 May 14.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, P. R. China.

Background: Trichinellosis is a serious zoonositc parasitosis worldwide. Because its clinical manifestations aren't specific, the diagnosis of trichinellosis is not easy to be made. Trichinella spiralis muscle larva (ML) excretory-secretory (ES) antigens are the most widely applied diagnostic antigens for human trichinellosis, but the major drawback of the ES antigens for assaying anti-Trichinella antibodies is the false negative in the early Trichinella infection period. Read More

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May 2018
4 Reads

The Golden jackal (Canis aureus) as an indicator animal for Trichinella britovi in Iran.

Parasite 2018 10;25:28. Epub 2018 May 10.

Department of Parasitology and Mycology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Nematodes of the genus Trichinella are zoonotic parasites causing trichinellosis. In Iran, these parasites occur in several animal species and rare cases have been recorded in humans. To monitor the epidemiological pattern of these parasites in the Khorasan-e-Razavi province, Northeastern Iran, muscle tissues were collected from the tongues of roadkill animals between 2016 and 2017: 295 stray dogs, one red fox (Vulpes vulpes), 12 golden jackals (Canis aureus), and one wild boar (Sus scrofa). Read More

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May 2018
0.820 Impact Factor

Correlates of Immune Response in Trichinella spiralis Infection.

Immunol Invest 2018 Aug 3;47(6):605-614. Epub 2018 May 3.

a Department of Medical Zoology , Kyung Hee University School of Medicine , Seoul , Korea.

Trichinella spiralis infection induces Trichinella-specific IgG antibody and high level of blood eosinophil. However, the kinetics induced by different parasite burdens during infectious periods remains unclear. In this study, rats were infected with 100, 1000, or 3000 larvae of T. Read More

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Possible case of trichinellosis associated with beaver (Castor fiber) meat.

J Helminthol 2018 May 3:1-3. Epub 2018 May 3.

Martsinovsky Institute of Medical Parasitology,Tropical and Vector Borne Diseases,Sechenov University,Moscow,Russia.

Although there have been occasional reports of rare and low-level trichinellae infestation in beavers, no human cases of beaver-associated trichinellosis have been described. This report presents a possible case of human trichinellosis linked to beaver meat. Increasing consumption of beaver meat necessitates raising awareness of this potential source of trichinellosis. Read More

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May 2018
2 Reads

First detection of Trichinella pseudospiralis infection in raccoon (Procyon lotor) in Central Europe.

Vet Parasitol 2018 Apr 14;254:114-119. Epub 2018 Mar 14.

Witold Stefański Institute of Parasitology, Polish Academy of Sciences, 00-818 Warsaw, Twarda 51/55, Poland.

The raccoon (Procyon lotor) is a North American carnivore introduced to Europe in the 20th Century. Raccoons are believed to be the potential hosts of many parasites, or to be involved in their transmission to other animals. Nematodes of the genus Trichinella can infect many carnivorous and omnivorous animals worldwide. Read More

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April 2018
2 Reads

Molecular cloning of enolase from Trichinella spiralis and the protective immunity in mice.

Acta Parasitol 2018 Jun;63(2):252-260

MOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China.

Trichinella spiralis, the main pathogen of trichinosis, infects a wide range of mammalian hosts and is one of the most widespread parasites worldwide. For parasites, glycolysis is the most important way to generate energy. Previous studies showed that some enzymes involved in the glycolytic pathway play roles in regulation the host immunity. Read More

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June 2018
3 Reads

A preliminary survey of Trichinella spp. in pigs raised under controlled housing conditions in Colombia: 2014-2016.

Parasite 2018 10;25:18. Epub 2018 Apr 10.

CIBAV research group, Veterinary Medicine School, Faculty of Agrarian Sciences, University of Antioquia, Carrera 75 No 65-87, Medellín, Colombia.

A preliminary survey of Trichinella spp. infection was conducted in Colombian swine herds between 2014 and 2016. A total of 1,773 pigs reared on farms under controlled housing conditions and processed in 34 slaughterhouses were tested either by the artificial digestion of pooled muscle samples (n = 1,173) or by serology (n = 600). Read More

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October 2018
21 Reads

Tongue has higher larval burden of Trichinella spp. than diaphragm in wolverines (Gulo gulo).

Vet Parasitol 2018 Apr 21;253:94-97. Epub 2018 Feb 21.

Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan, S7N 5B4, Canada.

Trichinella is an important zoonotic parasite found in a range of wildlife species harvested for food and fur in Canada. We compared larval intensity from tongue and diaphragm, the best predilection sites in other animal species, from naturally infected, wild wolverines (Gulo gulo) (n = 95). Muscle larvae of Trichinella spp. Read More

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April 2018
2.460 Impact Factor

Effects of iridoid-anthocyanin extract of Cornus mas L. on hematological parameters, population and proliferation of lymphocytes during experimental infection of mice with Trichinella spiralis.

Exp Parasitol 2018 May 27;188:58-64. Epub 2018 Mar 27.

Department of Internal Medicine and Clinic of Horses, Dogs and Cats, Division of Parasitology, Faculty of Veterinary Medicine, Wroclaw University of Environmental and Life Sciences, Norwida 31, 50-375 Wroclaw, Poland.

The influence of iridoid-anthocyanin aqueous extract of cornelian cherry fruits (CM) on hematological parameters, lymphocyte subsets and proliferation during Trichinella spiralis infection in mice was investigated. CM (100 mg/kg) was administered orally to T. spiralis-infected mice six times within a period encompassing three days prior to the infection and three days after the infection (dai). Read More

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May 2018
3 Reads

Characterization of a putative glutathione S-transferase of the parasitic nematode Trichinella spiralis.

Exp Parasitol 2018 Apr 26;187:59-66. Epub 2018 Feb 26.

Department of Parasitology, Medical College, Zhengzhou University, 40 Daxue Road, Zhengzhou 450052, PR China. Electronic address:

The aim of this study was to identify the biological characteristics and functions of a putative Trichinella spiralis glutathione S-transferase (TspGST). The results of real-time PCR and immunofluorescent test (IFT) showed that the TspGST gene was expressed at all of T. spiralis different developmental stages (muscle larvae, intestinal infective larvae, adult worms and newborn larvae). Read More

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April 2018
12 Reads

Trichinellosis Outbreak Linked to Consumption of Privately Raised Raw Boar Meat - California, 2017.

MMWR Morb Mortal Wkly Rep 2018 Mar 2;67(8):247-249. Epub 2018 Mar 2.

On January 15, 2017, a hospital physician notified the Alameda County Public Health Department (ACPHD) in California of a patient with a suspected diagnosis of trichinellosis, a roundworm disease transmitted by the consumption of raw or undercooked meat containing Trichinella spp. larvae (1). A family member of the initial patient reported that at least three other friends and family members had been evaluated at area hospitals for fever, myalgia, abdominal pain, diarrhea, and vomiting. Read More

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March 2018
7 Reads

Molecular identification of Sarcocystis lutrae in the European otter (Lutra lutra) and the European badger (Meles meles) from the Czech Republic.

Authors:
Ondřej Máca

Parasitol Res 2018 Mar 7;117(3):943-945. Epub 2018 Feb 7.

Department of Pathology and Parasitology, State Veterinary Institute Prague, Sídlištní 136/24, 165 00, Prague 6 - Lysolaje, Czech Republic.

Muscular sarcosporidial infections by Sarcocystis lutrae (Apicomplexa: Sarcocystidae) from the otter (Lutra lutra) and badger (Meles meles) (Carnivora: Mustelidae) were found in the Czech Republic. As part of a diversity evaluation of Sarcocystis in wild carnivores during 2016-2017, samples of diaphragm, tongue and hind-limb muscles were collected from nine districts, examined by compression and characterized molecularly. Cyst walls were thin, with no visible protrusions, and histological sections of infected muscle tissue showed no host responses. Read More

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March 2018
4 Reads

A Community-Based Study to Estimate the Seroprevalence of Trichinellosis and Echinococcosis in the Roma and Non-Roma Population of Slovakia.

Int J Environ Res Public Health 2018 02 2;15(2). Epub 2018 Feb 2.

Department of Internal Medicine, Hospital Poprad, 058 01 Poprad, Slovakia.

Trichinellosis and cystic and alveolar echinococcosis are serious parasitic diseases transmissible between animals and humans. Moreover, alveolar echinococcosis is considered one of the most dangerous of human helminthoses. Roma communities are particularly numerous in Central and Eastern Europe. Read More

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February 2018
6 Reads

The epidemiology of trichinellosis in the Arctic territories of a Far Eastern District of the Russian Federation.

J Helminthol 2018 Jan 31:1-8. Epub 2018 Jan 31.

Center of Parasitology, A.N. Severtsov's Institute of Ecology and Evolution,33 Leninsky prospekt,Moscow,119071,Russia.

Trichinellosis, a zoonotic disease caused by nematodes of the genus Trichinella, is still a public health concern in the Arctic. The aims of this study were to investigate the seroprevalence of anti-Trichinella IgG in aboriginal peoples of two settlements in the Chukotka Autonomous Okrug (Russian Federation) on the Arctic coast of the Bering Sea, and to evaluate the survival of Trichinella nativa larvae in local fermented and frozen meat products. A seroprevalence of 24. Read More

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January 2018
1 Read

Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization.

Front Immunol 2017 15;8:1844. Epub 2018 Jan 15.

Department of Clinical Immunology and Transplantology, Medical University of Gdańsk, Gdańsk, Poland.

Cellular therapies with CD4+ T regulatory cells (Tregs) hold promise of efficacious treatment for the variety of autoimmune and allergic diseases as well as posttransplant complications. Nevertheless, current manufacturing of Tregs as a cellular medicinal product varies between different laboratories, which in turn hampers precise comparisons of the results between the studies performed. While the number of clinical trials testing Tregs is already substantial, it seems to be crucial to provide some standardized characteristics of Treg products in order to minimize the problem. Read More

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January 2018
41 Reads

Therapeutic Effects of Resiniferatoxin Related with Immunological Responses for Intestinal Inflammation in Trichinellosis.

Korean J Parasitol 2017 Dec 31;55(6):587-599. Epub 2017 Dec 31.

Laboratory of Cell Biology and Microbiology, Academic Unit of Biological Sciences, Autonomous University of Zacatecas, Zacatecas, Zacatecas, México.

The immune response against Trichinella spiralis at the intestinal level depends on the CD4+ T cells, which can both suppress or promote the inflammatory response through the synthesis of diverse cytokines. During the intestinal phase, the immune response is mixed (Th1/Th2) with the initial predominance of the Th1 response and the subsequent domination of Th2 response, which favor the development of intestinal pathology. In this context, the glucocorticoids (GC) are the pharmacotherapy for the intestinal inflammatory response in trichinellosis. Read More

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December 2017
17 Reads

Comparative proteomics analysis of Trichinella spiralis muscle larvae exposed to albendazole sulfoxide stress.

Acta Trop 2018 Sep 26;185:183-192. Epub 2017 Dec 26.

Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; Key Clinical Laboratory of Henan Province, Zhengzhou 450052, China. Electronic address:

The drug albendazole (ABZ) has a positive effect against Trichinella spiralis infection and has been used for the treatment and prevention of trichinellosis in humans and animals. However, the molecular mechanism ofthe effects of ABZ on T. spiralis remains unknown. Read More

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September 2018
21 Reads

Prevalence of spp. Infections in Hunted Wild Boars in Northern Iran.

Iran J Public Health 2017 Dec;46(12):1712-1719

Dept. of Medical Parasitology & Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Trichinellosis is an important and neglected foodborne zoonotic infectious disease in worldwide. The most human outbreaks in recent years have been related to consumption of wild boar meat. This cross-sectional study determined the prevalence of spp. Read More

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December 2017
17 Reads

Border zone brain lesions due to neurotrichinosis.

Int J Infect Dis 2018 Feb 15;67:43-45. Epub 2017 Dec 15.

University of Medicine and Pharmacy "Victor Babes" Timisoara, Department of Neurology, Romania; Clinical Emergency County Hospital Timisoara, Department of Neurology, Romania.

Trichinosis is a parasitic disease that, due to variable clinical syndromes, is often underrecognized. We present the case of a patient with eosinophilia, focal neurological signs and multiple bilateral brain lesions, distributed mainly in the border zones. The diagnostic workup revealed neurotrichinosis, which should be suspected even without a clear history of consumption of poorly cooked meat. Read More

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February 2018
3 Reads

Trichinella spp. biomass has increased in raccoon dogs (Nyctereutes procyonoides) and red foxes (Vulpes vulpes) in Estonia.

Parasit Vectors 2017 Dec 16;10(1):609. Epub 2017 Dec 16.

Institute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Tartu, Estonia.

Background: Raccoon dogs and red foxes are well-adapted hosts for Trichinella spp. The aims of this study were to estimate Trichinella infection prevalence and biomass and to investigate which Trichinella species circulated in these indicator hosts in Estonia.

Methods: From material collected for evaluating the effectiveness of oral vaccination program for rabies eradication in wildlife, samples from 113 raccoon dogs and 87 red foxes were included in this study. Read More

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December 2017
1 Read

The tricky "trichs" in dermatology!

Indian J Dermatol Venereol Leprol 2018 Jan-Feb;84(1):109-113

Consultant Dermatologist and Trichologist, Eugenix Skin and Hair Sciences, Gurgaon, Haryana, India.

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November 2018
4 Reads

A novel antigenic cathepsin B protease induces protective immunity in Trichinella-infected mice.

Vaccine 2018 01 2;36(2):248-255. Epub 2017 Dec 2.

Sun Yat-sen University Zhongshan School of Medicine, Key Laboratory of Tropical Disease Control (Sun Yat-Sen University), Ministry of Education, Guangzhou 510080, China. Electronic address:

Trichinellosis is a foodborne disease that remains a public health hazard and an economic problem in food safety. Vaccines against the parasite can be an effective way to control this disease; however, commercial vaccines against Trichinella infection are not yet available. Trichinella cathepsin B proteins appear to be promising targets for vaccine development. Read More

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January 2018
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Immuno-proteomic analysis of Trichinella spiralis, T. pseudospiralis, and T. papuae extracts recognized by human T. spiralis-infected sera.

Parasitol Res 2018 Jan 30;117(1):201-212. Epub 2017 Nov 30.

Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

The present study explored potentially immunogenic proteins of the encapsulated (Trichinella spiralis) and non-encapsulated (T. pseudospiralis, T. papuae) species within the genus Trichinella. Read More

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January 2018
21 Reads

A competitive enzyme-linked immunosorbent assay for rapid detection of antibodies against Trichinella spiralis and T. britovi - one test for humans and swine.

J Helminthol 2017 Nov 23:1-9. Epub 2017 Nov 23.

Serbian National Reference Laboratory for Trichinellosis (NRLT),Institute for the Application of Nuclear Energy - INEP,University of Belgrade,Banatska 31b,11080 Belgrade,Serbia.

Infection with parasites from the Trichinella genus occurs in many vertebrates but disease only occurs in humans (trichinellosis). Humans are infected after the consumption of raw or undercooked meat from infected wild or domestic animals (usually swine or horses). Using the monoclonal antibody (mAb) 7C2C5, specific for an epitope unique to the muscle larvae of the genus Trichinella, we have developed a competitive enzyme-linked immunosorbent assay (c-ELISA) that enables the rapid detection of Trichinella-specific antibodies in sera originating from two different host species (human, swine) infected with either Trichinella spiralis or Trichinella britovi. Read More

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November 2017
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Detection of Experimental Swine Trichinellosis Using Commercial Elisa Test.

Pol J Vet Sci 2017 Sep;20(3):445-454

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The aim of the study carried out on ten young (10-week old) pigs of the native Polish Large White breed experimentally infected with a low dose of 300 invasive muscle larvae (ML) of Trichinella spiralis was intravital detection of trichinellosis using the E-S ELISA test, determination of a variation level of IgG antibodies against excretory-secretory (E-S) antigens of T. spiralis muscle larvae and finally, describing the intensity of T. spiralis larvae infection in selected muscles. Read More

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September 2017
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