5,227 results match your criteria Trichinosis


-associated myocarditis mimicking acute myocardial infarction.

Acta Clin Belg 2020 Jul 4:1-6. Epub 2020 Jul 4.

Department of Cardiology, Brugmann University Hospital , Brussels, Belgium.

Background Trichinellosis is a parasitic infection caused by nematodes of the genus , and its principal mode of transmission is the consumption of raw or undercooked contaminated meat. Cardiac involvement in trichinellosis is unusual, yet it represents the most frequent cause of death. Here, we report a case in which -associated myocarditis simulated a myocardial infarction. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17843286.2020.1790867DOI Listing

Celebrating the 60th Anniversary of the International Commission on Trichinellosis: An early example of Franco-German collaboration to study the Trichinellosis outbreak of Emersleben (1883).

Vet Parasitol 2020 Jun 25:109175. Epub 2020 Jun 25.

Faculté de Médecine, Paris University, 15 rue de l'Ecole de médecine, 75006, Paris, France. Electronic address:

Two prominent physicians, Grancher and Brouardel, were sent by the French Health authorities to study the severe ongoing outbreak of trichinellosis in Emersleben, Germany (1883). They produced a highly accurate description of the outbreak and confirmed that they had never observed such cases in France. Grancher performed two necropsies and very precisely described the histological lesions provoked by the larvae entering and transforming muscular fibers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109175DOI Listing

Early days of the International Commission on Trichinellosis (1958-1972).

Ann Parasitol 2020 ;66(2):259-263

USDA, ARS, Animal Parasitic Diseases Lab, B1180 BARC-East, Beltsville, MD 20705, USA.

Herein we describe the origin of the International Commission on Trichinellosis more than 60 years after its foundation. We attempt to clarify previous debate over the founding presidents and particularly the role of Polish parasitologist, Zbigniew Kozar. Seminal and core proceedings of the Commission published in Wiadomości Parazytologiczne and other records were used to advance this goal. Read More

View Article

Download full-text PDF

Source
January 2020

Changes in the Expression of TLR2 During the Intestinal Phase of Trichinellosis.

J Vet Res 2020 Jun 21;64(2):269-274. Epub 2020 Apr 21.

Department of Biology and Medical Parasitology, Poznan University of Medical Sciences, 61-701 Poznań, Poland.

Introduction: Toll-like receptors (TLRs) play an important role in fast activation of the immune response to a variety of pathogens, including parasites. In this study, we focused on TLR2, because this receptor is one of the best known and most frequently analysed members of the TLR family. The aim of this study was to assess the effect of on expression of TLR2 during the intestinal stage of infection. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2478/jvetres-2020-0027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305650PMC

A common source for a trichinellosis outbreak reported in France and Serbia in 2017.

Euro Surveill 2020 Jun;25(24)

Reference Laboratory for Human Trichinellosis, Hôpital Cochin, Hôpitaux Universitaires Paris centre, APHP, Faculty of Medicine, Université Paris Descartes, Paris, France.

Trichinellosis is a rare parasitic zoonosis in the European Union. Meat from backyard pigs was the common source for a trichinellosis outbreak caused by , which occurred in France and Serbia in the beginning of 2017. An epidemiological study was conducted in France and Serbia to determine the extent of the outbreak, to identify its source and to implement control measures. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2807/1560-7917.ES.2020.25.24.1900527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315721PMC

Lipid profile of Trichinella papuae muscle-stage larvae.

Sci Rep 2020 Jun 23;10(1):10125. Epub 2020 Jun 23.

Department of Molecular Tropical Medicine and Genetics, Faculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand.

Outbreaks of trichinellosis caused by Trichinella papuae have been reported in South-East Asia. Mebendazole and thiabendazole are the treatments of choice for trichinellosis; however, both drugs result in significant side effects and are less effective for muscle-stage larvae (L1). An alternative therapeutic agent is needed to improve treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-67297-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311410PMC

The first analysis of Trichinella spiralis and Trichinella britovi adult worm excretory-secretory proteins by two-dimensional electrophoresis coupled with LC-MS/MS.

Vet Parasitol 2020 May 17:109096. Epub 2020 May 17.

Witold Stefański Institute of Parasitology, Polish Academy of Sciences, Twarda 51/55, 00-818 Warszawa, Poland. Electronic address:

The two most common Trichinella species present in European countries are Trichinella spiralis and Trichinella britovi. The consumption of raw or undercooked meat with invasive larvae results in trichinellosis. Currently, the most commonly used sources for detecting specific anti-Trichinella antibodies is ELISA with the muscle larvae (ML) excretory-secretory (E-S) proteins. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109096DOI Listing

Study of Trichinella patagoniensis in wild boars.

Vet Parasitol 2020 Jun 9:109166. Epub 2020 Jun 9.

Universidad de Buenos Aires. Facultad de Ciencias Veterinarias, Cátedra de Parasitología y Enfermedades Parasitarias, Av Chorroarín 280, C1427CWO CABA, Buenos Aires, Argentina; CONICET - Universidad de Buenos Aires. Facultad de Ciencias Veterinarias, Instituto de Investigaciones en Producción Animal (INPA). Buenos Aires, Argentina.

Trichinellosis is a zoonotic disease, which represents a significant public health concern in some South American countries, such as Argentina and Chile. Its impact is essentially due to absence of adequate control measures on meat from game animals, as well as the presence of illegal slaughterhouses and the trade of meat products without being tested for this parasite. In Argentina, trichinellosis is an endemic disease. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109166DOI Listing

Effects of TLR agonists on immune responses in Trichinella spiralis infected mice.

Parasitol Res 2020 Jun 13. Epub 2020 Jun 13.

Key Laboratory for Zoonoses Research, Ministry of Education, Institute of Zoonoses, College of Veterinary Medicine, OIE Collaborating Center on Foodborne Parasites in Asian-Pacific Region, Jilin University, Changchun, 130062, People's Republic of China.

Human trichinellosis is acquired by eating raw or undercooked meats carrying muscle larvae of Trichinella spp. Toll-like receptors (TLRs) are essential components of the innate immune system. However, little is known about the potential application of TLR agonists for immunotherapy against Trichinella spiralis (T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00436-020-06747-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292931PMC
June 2020
2.327 Impact Factor

Effect of Genotype and Sex of the Host on the Bioavailability of Novel Albendazole Microcrystals Based on Chitosan and Cellulose Derivatives.

AAPS PharmSciTech 2020 May 20;21(5):149. Epub 2020 May 20.

IQUIR-CONICET, Suipacha 570, S2002LRK, Rosario, Argentina.

Albendazole (ABZ), an anthelmintic compound widely used in the treatment of systemic nematode infections, is included in the list of class II drugs based on the Biopharmaceutical Classification System. ABZ has limited effectiveness due to its poor water solubility and consequent low bioavailability. Bioavailability of novel ABZ microcrystals based on hydroxyethylcellulose (S4A) or chitosan (S10A) was studied in male and female mice of two inbred lines, from the murine CBi-IGE model of trichinellosis, differing in susceptibility to this parasitosis (line CBi/L, resistant; line CBi+, susceptible). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1208/s12249-020-01692-2DOI Listing

Molecular characterization of a Trichinella spiralis aspartic protease and its facilitation role in larval invasion of host intestinal epithelial cells.

PLoS Negl Trop Dis 2020 04 27;14(4):e0008269. Epub 2020 Apr 27.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, PR China.

Background: T. spiralis aspartic protease has been identified in excretion/secretion (ES) proteins, but its roles in larval invasion are unclear. The aim of this study was to characterize T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0008269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205320PMC

Protection against Trichinella spiralis in BALB/c mice via oral administration of recombinant Lactobacillus plantarum expressing murine interleukin-4.

Vet Parasitol 2020 Apr 2;280:109068. Epub 2020 Mar 2.

College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of Animal Production and Product Quality Safety of Ministry of Education, Jilin Agricultural University, Changchun, Jilin Province, 130118, PR China. Electronic address:

Interleukin-4 (IL-4), an immunomodulatory cytokine derived from activated T lymphocytes were shown to regulate Th2-type immune responses. It plays an important role in anti-parasitic infections. In this study, a recombinant plasmid was designed using murine IL-4 co-expressed with pgsA anchor system of Lactobacillus plantarum NC8 and was delivered by live Lactobacillus plantarum NC8, which exhibited an enhanced immunogenicity in protection of BALB/c mice from infection with Trichinella spiralis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109068DOI Listing

Species identification of Trichinella originated from various host and different geographical location by MALDI-TOF.

Exp Parasitol 2020 Jun 6;213:107890. Epub 2020 Apr 6.

JRU BIPAR, ANSES, Alfort National Veterinary School, INRA, Animal Health Laboratory, 14 Rue Pierre et Marie Curie, 94701, Maisons-Alfort Cedex, France.

The foodborne zoonotic nematode Trichinella spp. can cause human trichinellosis when raw or undercooked contaminated meat is ingested. To date, twelve Trichinella species/genotypes have been described. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2020.107890DOI Listing

Resveratrol reduces oxidative damage and inflammation in mice infected with .

J Helminthol 2020 Apr 2;94:e140. Epub 2020 Apr 2.

Pathology Department, Faculty of Medicine, Tanta University, Egypt.

Trichinellosis is a serious food-borne zoonotic infection of cosmopolitan distribution. Currently, treatment for trichinellosis is far from ideal. Given the important role of oxidative stress and immune-mediated inflammation in the pathogenesis of trichinellosis, this study was designed to evaluate the possible protective effects of resveratrol (RSV) during the intestinal and muscular phases of Trichinella spiralis infection in mice. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S0022149X20000206DOI Listing

Early diagnosis of experimental Trichinella spiralis infection by nano-based enzyme-linked immunosorbent assay (nano-based ELISA).

Authors:
Maha M Gomaa

Exp Parasitol 2020 May 24;212:107867. Epub 2020 Feb 24.

Department of Medical Parasitology, Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address:

Trichinellosis is a serious foodborne zoonotic disease. It is an important threat to public health all over the world. Although anti-Trichinella IgG detection is the most widely used method for diagnosis of trichinellosis, but there is an obvious window between clinical symptoms and positive serology. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2020.107867DOI Listing

Clinical and epidemiological descriptions from trichinellosis outbreaks in Bulgaria.

Exp Parasitol 2020 May 13;212:107874. Epub 2020 Mar 13.

Parasitology Lab, Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Adamstuen Campus, PO Box 369 Sentrum, 0102, Oslo, Norway.

Bulgaria is one of European countries where trichinellosis continues to be regularly diagnosed and registered. The clinical and epidemiological features of 72 cases of trichinellosis associated with five outbreaks caused by Trichinella spiralis and Trichinella britovi between 2009 and 2011, are described. At hospital admission, patients were often initially treated with antibiotics, without any improvement. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2020.107874DOI Listing

The Disease Ecology, Epidemiology, Clinical Manifestations, and Management of Trichinellosis Linked to Consumption of Wild Animal Meat.

Wilderness Environ Med 2020 Jun 10;31(2):235-244. Epub 2020 Mar 10.

Program in Environmental and Occupational Health Sciences, School of Public Health, Louisiana State University Health Sciences Center (LSUHSC), New Orleans, LA; Louisiana State University School of Veterinary Medicine, Baton Rouge, LA.

Historically, human trichinellosis was caused by Trichinella spiralis and transmitted to humans by consumption of undercooked domestic pork. Today, most cases of trichinellosis are caused by other Trichinella species and transmitted by consumption of raw or undercooked wild game meats. Given the increasing global prevalence of wild animal meat-linked trichinellosis, the objectives of this review are: 1) to describe the life cycle and global distribution of Trichinella worms; 2) to describe the changing epidemiology of trichinellosis; 3) to describe the clinical phases of trichinellosis; 4) to recommend the latest diagnostic tests; and 5) to recommend treatment and prevention strategies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.wem.2019.12.003DOI Listing

Alternative Activation of Macrophages in Mice Peritoneal Cavities and Diaphragms by Newborn Larvae of .

Yonago Acta Med 2020 Feb 24;63(1):34-41. Epub 2020 Jan 24.

Division of Medical Zoology, Department of Microbiology and Immunology, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.

Background: Trichinellosis is a serious zoonosis with a worldwide distribution. Fecund adult worms in the intestine release newborn larvae (NBL) that enter the general circulation from 4 days post infection (dpi). Alternatively activated macrophages in the peritoneal cavities and the diaphragms in infected mice have been reported. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.33160/yam.2020.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028538PMC
February 2020

Vaccination with a DNase II recombinant protein against Trichinella spiralis infection in pigs.

Vet Parasitol 2020 Mar 5:109069. Epub 2020 Mar 5.

Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, China. Electronic address:

Trichinellosis caused by Trichinella spiralis (T. spiralis) is an important public health problem. DNase II is an acidic endonuclease that catalyzes the degradation of DNA into oligonucleotides. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.vetpar.2020.109069DOI Listing

Comparative expression profiles of host circulating miRNAs in response to Trichinella spiralis infection.

Vet Res 2020 Mar 11;51(1):39. Epub 2020 Mar 11.

Department of Clinical Laboratory, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.

Trichinellosis is an important food-borne parasitic zoonosis throughout the world. At present, the mechanisms of Trichinella spiralis infection remain unclear. Acquiring detailed information on the host-Trichinella interaction would be beneficial for the development of new strategies for trichinellosis control. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13567-020-00758-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7065375PMC

Towards a better understanding of the benefits and risks of country food consumption using the case of walruses in Nunavik (Northern Quebec, Canada).

Sci Total Environ 2020 Jun 13;719:137307. Epub 2020 Feb 13.

Département de médecine sociale et préventive, Université Laval, Québec City, Québec, Canada; Axe Santé des populations et pratiques optimales en santé, Centre de recherche du CHU de Québec, Université Laval, 1050 Chemin Ste-Foy, Québec City, Québec G1S 4L8, Canada.

Food insecurity affects Inuit communities. One solution is to consume locally harvested foods, named country foods. However, some country foods are not eaten as often as before, and pressures including contaminants and environmental changes threaten the health of Arctic fauna, thus its suitability for local consumption. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scitotenv.2020.137307DOI Listing

Preface: International Commission on Trichinellosis recommendations for the detection and control of .

Food Waterborne Parasitol 2019 Dec 14;17:e00063. Epub 2019 Aug 14.

United States Department of Agriculture, Agricultural Research Service, Animal Parasitic Diseases Lab, B1180 BARC-East, Beltsville, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2019.e00063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034006PMC
December 2019

International Commission on Trichinellosis: Recommendations for quality assurance in digestion testing programs for .

Food Waterborne Parasitol 2019 Sep 5;16:e00059. Epub 2019 Jun 5.

National Academy of Sciences, 500 Fifth Street NW, Washington, DC 20001, USA.

Effective performance of digestion testing methods for , and their use for the detection of infected animals and the prevention of human trichinellosis require system-wide incorporation of appropriate quality assurance (QA) practices. The recommendations of the International Commission on Trichinellosis (ICT) aim to facilitate reliable test results when laboratories operate within a quality management system (QMS) which includes: 1) a quality manual (or similar documentation of the QMS); 2) a validated test method with identified critical control points; 3) a training program; 4) procedures utilizing proficiency testing and other methods to confirm technical capability of analysts; 5) equipment calibration and maintenance; 6) standard operating procedures, related documentation and reporting; 7) procedures to enable continuous monitoring and improvements; and 8) regular internal and third party audits. The quality manual or similar documentation describes the QMS within a testing laboratory, and lists the QA policies and good laboratory practices. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2019.e00059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033998PMC
September 2019

International Commission on Trichinellosis: Recommendations on pre-harvest control of in food animals.

Food Waterborne Parasitol 2019 Jun 18;15:e00039. Epub 2019 Mar 18.

Centre for Food-borne and Animal Parasitology, Canadian Food Inspection Agency, 116 Veterinary Road, Saskatoon, SK S7N 2R3, Canada.

Transmission of to domestic livestock, notably pigs, is limited to certain risk factors including feeding of raw meat-containing waste products or animal carcasses and exposure to infected rodents and wildlife. Prevention of infection in food animals is dependent on eliminating risk of exposure to these potential sources of By implementing conditions of controlled management, pig herds can be considered to pose a negligible risk for , and groups of herds which follow these same conditions can be considered to be a compartment with negligible risk for . Pork from pigs originating from a negligible risk herd or compartment would not require further testing or processing to protect consumers from this parasite. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2019.e00039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034043PMC

International Commission on Trichinellosis: Recommendations for genotyping Trichinella muscle stage larvae.

Food Waterborne Parasitol 2019 Jun 10;15:e00033. Epub 2019 Mar 10.

Agricultural Research Service, Animal Parasitic Diseases Lab, Beltsville, MD, USA.

Being able to identify the species or genotype of is of paramount importance not only for epidemiological studies but to better ascertain the source of outbreaks that still occur worldwide. This has become more critical in recent years given the increase in imported meat products and the relationship that wild animals play in the domestic and sylvatic transmission cycles. In contrast to a time when the genus was considered monospecific, research in recent years has revealed that the genus consists of 9 species and at least 3 additional genotypes which have yet to be named. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2018.e00033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034036PMC

International Commission on Trichinellosis: Recommendations on post-harvest control of in food animals.

Food Waterborne Parasitol 2019 Mar 21;14:e00041. Epub 2019 Feb 21.

National Academy of Sciences, 500 Fifth Street NW, Washington, DC 20001, United States of America.

Domestic and wild animals which consume meat are at risk of becoming infected with and therefore may pose a public health risk. Among domestic livestock, pigs are most commonly associated with infection, but human outbreaks have also resulted from consumption of horsemeat, wild boar, bear, walrus and other wild animals. For animals that are not produced under controlled management conditions and for wild animals, specific steps should be taken to prevent human exposure to . Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2019.e00041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033995PMC

International Commission on Trichinellosis: Recommendations on the use of serological tests for the detection of infection in animals and humans.

Food Waterborne Parasitol 2019 Mar 5;14:e00032. Epub 2019 Feb 5.

USDA, ARS, ANRI, APDL, BARC-East, Beltsville, MD 20705, USA.

Serological methods are widely used for detection of infections in animals and humans. The recommendations provided here take into account the best current methods for the serological detection of infection. They are based on current scientific information including unpublished data from laboratories with relevant expertise in this field. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.fawpar.2018.e00032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034015PMC

Molecular characterization of a Trichinella spiralis elastase-1 and its potential as a diagnostic antigen for trichinellosis.

Parasit Vectors 2020 Feb 24;13(1):97. Epub 2020 Feb 24.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

Background: Trichinella spiralis muscle larval (ML) excretion/secretion (ES) antigen is the most widely used diagnostic antigen of trichinellosis, but preparation of ES antigen requires collecting worms from infected animals, and detection of specific IgG against ML ES antigen may result in a false negative at the early stage of infection. The aim of the study was to characterize T. spiralis elastase-1 (TsEla) and to evaluate its potential as diagnostic antigen for trichinellosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13071-020-3981-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7041205PMC
February 2020

Primary characterization of the immune response in pigs infected with Trichinella spiralis.

Vet Res 2020 Feb 21;51(1):17. Epub 2020 Feb 21.

Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin University, Changchun, 130000, China.

Trichinellosis, which is caused by Trichinella spiralis (T. spiralis), is a serious zoonosis. Pigs play an important role in the transmission of human trichinellosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13567-020-0741-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035712PMC
February 2020
2.815 Impact Factor

Development of genome-wide polymorphic microsatellite markers for Trichinella spiralis.

Parasit Vectors 2020 Feb 11;13(1):58. Epub 2020 Feb 11.

Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine, Jilin University, Changchun, 130062, Jilin, People's Republic of China.

Background: Trichinella nematodes are globally distributed food-borne pathogens, in which Trichinella spiralis is the most common species in China. Microsatellites are a powerful tool in population genetics and phylogeographic analysis. However, only a few microsatellite markers were reported in T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13071-020-3929-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014596PMC
February 2020
3.430 Impact Factor

Chitosan coated nanostructured lipid carriers for enhanced in vivo efficacy of albendazole against Trichinella spiralis.

Carbohydr Polym 2020 Mar 7;232:115826. Epub 2020 Jan 7.

Department of Pharmaceutical Technology, Faculty of Pharmacy, Tanta University, Tanta, Egypt. Electronic address:

The study investigated chitosan coated nanostructured lipid carriers (NLCs) for oral delivery of albendazole in treatment of trichinellosis. NLCs comprised precirol and oleic acid with Tween and Span 80. Dicetylphosphate was used as charging agent to allow chitosan coating. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.carbpol.2019.115826DOI Listing

Regulation of host immune cells and cytokine production induced by Trichinella spiralis infection.

Parasite 2019 19;26:74. Epub 2019 Dec 19.

College of Animal Science and Technology, Inner Mongolia University for Nationalities, Inner Mongolia, 028042 Tongliao, PR China - Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis/College of Veterinary Medicine, Jilin University, 130000 Changchun, PR China.

The nematode Trichinella spiralis can cause immunoregulation during the early phase of infection. However, previous studies are still insufficient for a full understanding of this phenomenon and its underlying mechanism. In this study, immune cells and cytokine profiles of T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/parasite/2019074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921962PMC
May 2020
0.822 Impact Factor

Human trichinosis mimicking polymyositis.

Int J Infect Dis 2020 03 13;92:19-20. Epub 2019 Dec 13.

Servicio de infectología, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Gonzalitos y Madero SN, Mitras Centro, 64460 Monterrey, NL, Mexico. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijid.2019.12.014DOI Listing

Vaccination of mice with a recombinant novel cathepsin B inhibits Trichinella spiralis development, reduces the fecundity and worm burden.

Parasit Vectors 2019 Dec 11;12(1):581. Epub 2019 Dec 11.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

Background: Trichinella spiralis is a major zoonotic tissue-dwelling nematode, which is a public health concern and a serious hazard to animal food safety. It is necessary to exploit an anti-Trichinella vaccine to interrupt the transmission of Trichinella infection among animals and from animals to humans. The purpose of the present study was to characterize the novel T. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13071-019-3833-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907330PMC
December 2019
3.430 Impact Factor

Zoonoses and potential zoonoses of bears.

Zoonoses Public Health 2020 Feb 12;67(1):3-13. Epub 2019 Dec 12.

Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, California.

Captive and free-ranging wild bears can carry and transmit several zoonotic pathogens. A review of nearly 90 years of scientific publications concerning confirmed and potential zoonotic diseases that can be present in any of the eight species of bears in the world was conducted. The findings were organized amongst the following disease sections: bacterial, viral, protozoal, mycotic, helminth and arthropod-borne. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/zph.12674DOI Listing
February 2020

Molecular characterization of a Trichinella spiralis enolase and its interaction with the host's plasminogen.

Vet Res 2019 Dec 5;50(1):106. Epub 2019 Dec 5.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

The binding and activation of host plasminogen (PLG) by worm surface enolases has been verified to participate in parasite invasion, but the role of this processes during Trichinella spiralis infection has not been clarified. Therefore, the expression and immunolocalization of a T. spiralis enolase (TsENO) and its binding activity with PLG were evaluated in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13567-019-0727-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894503PMC
December 2019

Risk-based surveillance for meat-borne parasites.

Exp Parasitol 2020 Jan 22;208:107808. Epub 2019 Nov 22.

Section of Epidemiology, Vetsuisse Faculty, University of Zürich, Switzerland.

There is a plethora of meat-borne hazards - including parasites - for which there may be a need for surveillance. However, veterinary services worldwide need to decide how to use their scarce resources and prioritise among the perceived hazards. Moreover, to remain competitive, food business operators - irrespective of whether they are farmers or abattoir operators - are preoccupied with maintaining a profit and minimizing costs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exppara.2019.107808DOI Listing
January 2020

Genotyping and Phylogenetic Position of Isolates from Different Geographical Locations in China.

Front Genet 2019 31;10:1093. Epub 2019 Oct 31.

Department of Parasitology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou, China.

In China, the nematode is the main aetiological agent of human trichinellosis. We performed multi-locus microsatellite typing of isolates to improve the current knowledge of the evolution and population diversity. First, seven polymorphic microsatellite loci were used to infer the genetic diversity of collected in 10 endemic regions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2019.01093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834790PMC
October 2019

Trichinella britovi outbreak: Epidemiological, clinical, and biological features.

Med Mal Infect 2019 Nov 12. Epub 2019 Nov 12.

School of Medicine, University of Belgrade, Belgrade, Serbia.

Objectives: We aimed to describe the first cases of human trichinellosis due to Trichinella britovi in Serbia. A large trichinellosis outbreak due to the consumption of wild boar meat products took place during the 2015-2016 winter.

Patients And Methods: In January 2016, the Department of Infectious Diseases in Uzice examined 111 individuals with clinical and biological signs of trichinellosis, of whom 19 were hospitalized. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.medmal.2019.10.008DOI Listing
November 2019
0.912 Impact Factor

Effect of Wortmannilactone F on Enteral in Mice.

Vector Borne Zoonotic Dis 2020 03 11;20(3):205-211. Epub 2019 Nov 11.

Department of Parasitology, Dalian Medical University, Dalian, China.

Trichinosis is a worldwide zoonotic disease closely related to cultural and dietary habits caused by a nematode spp. The drugs for its prevention and treatment are still not thoroughly defined. Wortmannilactone F was used to value the therapeutic effects on the worm reduction rates, change of the intestinal mucosa, and the host's body's immune activity in this experiment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/vbz.2019.2482DOI Listing

The Immunological Properties of Recombinant Multi-Cystatin-Like Domain Protein From Produced in Yeast.

Front Immunol 2019 11;10:2420. Epub 2019 Oct 11.

Witold Stefanski Institute of Parasitology, Polish Academy of Sciences, Warsaw, Poland.

Trichinellosis is a globally-distributed zoonotic parasitic disease caused by nematode worms of the genus . One of the most common species of known to affect human health is ; however, it is relatively poorly investigated. A thorough knowledge of the proteins expressed by is important when developing immunological detection methods and vaccines and studying its interactions with the host. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.02420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797592PMC
October 2019

Biomolecular Changes and Cortical Neurodegenerative Lesions in Infected BALB/c Mice: A Preliminary Study Elucidating a Potential Relationship Between Systemic Helminthic Infections and Idiopathic Parkinson's.

Helminthologia 2018 Dec 27;55(4):261-274. Epub 2018 Oct 27.

Pathology, Tanta University, Faculty of Medicine, Tanta, Egypt.

Idiopathic Parkinson's (IP) is a neurodegenerative disease that is suspected to be due to exposure to infections during early life. Toxoplasmosishas been the only suspected parasitic infection in IP (Celik et al., 2010). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2478/helm-2018-0029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662001PMC
December 2018

A Simple and Rapid Staining Technique for Sex Determination of Larvae Parasites by Confocal Laser Scanning Microscopy.

Microsc Microanal 2019 12;25(6):1491-1497

Institute of Life Sciences and Technology, Daugavpils University, Daugavpils LV-5401, Latvia.

The roundworms of Trichinella genus are worldwide distributed and their prevalence in nature is high. Trichinella genus parasites are the causative agents of foodborne zoonosis trichinellosis. The main prevention and control of the infection are meat inspection by the magnetic stirrer method for the detection of Trichinella larvae in muscle samples. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S1431927619015046DOI Listing
December 2019

The unique contribution of a local response group in the field investigation and management of a trichinellosis outbreak in Nunavik (Québec, Canada).

Can J Public Health 2020 Feb 21;111(1):31-39. Epub 2019 Oct 21.

Département de médecine sociale et préventive, Université Laval, 2325 Rue de l'Université, Québec, Québec, G1V 0A6, Canada.

Setting: Consumption of raw game meats is important for Inuit health and well-being but may sometimes increase risk of exposure to parasites. In Nunavik, following trichinellosis outbreaks in the 1980s caused by raw walrus consumption, a diagnostic test was developed for the region and offered to all Inuit communities by 1997. Despite this prevention program, an important trichinellosis outbreak occurred in 2013, affecting 18 inhabitants of Inukjuak. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.17269/s41997-019-00255-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046848PMC
February 2020
1 Read

Sanguinarine has anthelmintic activity against the enteral and parenteral phases of trichinella infection in experimentally infected mice.

Acta Trop 2020 Jan 18;201:105226. Epub 2019 Oct 18.

College of Animal Science and Technology, Jilin Provincial Engineering Research Center of Animal Probiotics, Key Laboratory of animal production and product quality safety of Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address:

Trichinellosis is a zoonotic parasitic disease caused by Trichinella spiralis, and it is also a widely prevalent foodborne parasitic disease. At present, albendazole and benzimidazole are the most commonly used therapeutic drugs for the clinical treatment of trichinellosis, but they have many side effects. Sanguinarine is a benzophenanthridine alkaloid that has biological activity, such as antibacterial, antitumour and antiparasitic activities. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.actatropica.2019.105226DOI Listing
January 2020
2.270 Impact Factor

Th2 signals are not essential for the anti-arthritic effects of Trichinella spiralis in mice.

Parasite Immunol 2020 01 6;42(1):e12677. Epub 2019 Nov 6.

Department of Immunology and Parasitology, University of Occupational and Environmental Health, Kitakyushu, Japan.

Aims: Many parasitic helminths are known to alter host immune responses and consequently affect the progression of autoimmune and allergic diseases. The parasitic nematode Trichinella sp has been reported to suppress several experimental diseases in rodents, including experimental autoimmune encephalomyelitis, type 1 diabetes, colitis, airway inflammation and autoimmune arthritis. We tried to clarify requirement of Th2 cytokines in the anti-arthritic effects of Trichinella spiralis (Ts) against collagen-induced arthritis (CIA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pim.12677DOI Listing
January 2020
2 Reads

EphrinB2/ephB2-mediated myenteric synaptic plasticity: mechanisms underlying the persistent muscle hypercontractility and pain in postinfectious IBS.

FASEB J 2019 12 25;33(12):13644-13659. Epub 2019 Oct 25.

Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Patients with irritable bowel syndrome (IBS) show pain hypersensitivity and smooth muscle hypercontractility in response to colorectal distension (CRD). Synaptic plasticity, a key process of memory formation, in the enteric nervous system may be a novel explanation. This study aimed to explore the regulatory role of ephrinB2/ephB2 in enteric synaptic plasticity and colonic hyperreactive motility in IBS. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201901192RDOI Listing
December 2019
1 Read
5.043 Impact Factor

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

J Exp Med 2019 12 3;216(12):2714-2723. Epub 2019 Oct 3.

Wellcome Trust Centre for Cell Matrix Research, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

Host immunity to parasitic nematodes requires the generation of a robust type 2 cytokine response, characterized by the production of interleukin 13 (IL-13), which drives expulsion. Here, we show that infection with helminths in the intestine also induces an ILC2-driven, IL-13-dependent goblet cell hyperplasia and increased production of mucins (Muc5b and Muc5ac) at distal sites, including the lungs and other mucosal barrier sites. Critically, we show that type 2 priming of lung tissue through increased mucin production inhibits the progression of a subsequent lung migratory helminth infection and limits its transit through the airways. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20180610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888984PMC
December 2019
1 Read

Label-free quantitative proteomic analysis of molting-related proteins of Trichinella spiralis intestinal infective larvae.

Vet Res 2019 Sep 23;50(1):70. Epub 2019 Sep 23.

Department of Parasitology, Medical College, Zhengzhou University, Zhengzhou, 450052, China.

Molting is a key step for body-size expansion and environmental adaptation of parasitic nematodes, and it is extremely important for Trichinella spiralis growth and development, but the molting mechanism is not fully understood. In this work, label-free LC-MS/MS was used to determine the proteome differences between T. spiralis muscle larvae (ML) at the encapsulated stage and intestinal infective larvae (IIL) at the molting stage. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13567-019-0689-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757440PMC
September 2019
2 Reads