Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):e9-e12
*Department of Ophthalmology, Harvard Medical School; †David G. Cogan Laboratory of Ophthalmic Pathology, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts, U.S.A.; ‡Department of Ophthalmic Pathology, CBLPath, Inc., Rye Brook, New York, U.S.A.; §Oculoplastic & Orbital Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, U.S.A.; ‖Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, U.S.A.
A 16-year-old African American male, the youngest patient to date, presented with a well-circumscribed upper eyelid lesion. On excision, the dermal nodule was contiguous with the epidermis, displayed trichohyalin-like bodies in an expanded outer root sheath, and was composed chiefly of small cellular clusters separated by a prominent network of periodic acid Schiff -positive hyaline bands of basement membrane material. The tumor cells were positive for high molecular weight cytokeratins (CK) 5/6, CK14, and CK34βE12 and were negative for CK7, carcinoembryonic antigen and epithelial membrane antigen. Read More