Search our Database of Scientific Publications and Authors

I’m looking for a

    771 results match your criteria Trichiasis

    1 OF 16

    Trachoma in Yunnan province of southwestern China: findings from trachoma rapid assessment.
    BMC Ophthalmol 2018 Apr 17;18(1):97. Epub 2018 Apr 17.
    Department of Ophthalmology, Yunnan Key Laboratory for prevention and treatment of eye diseases, Yunnan Innovation Team for Cataract and Ocular fundus Disease (2017HC010), Yunnan Eye Institute, Yunnan Eye Hospital, The 2nd People's Hospital of Yunnan Province, Kunming, China.
    Background: To understand the situation of active trachoma among children aged 6 to 8 years old and scarring trachoma among those aged 15 and over in Yunnan Province, South-western China.

    Methods: A rapid assessment of trachoma was conducted to determine the presence or absence of trachoma in Yunnan. Through risk assessment, 9 sites in 8 suspected trachoma epidemic counties were selected. Read More

    Oral doxycycline for the prevention of postoperative trachomatous trichiasis in Ethiopia: a randomised, double-blind, placebo-controlled trial.
    Lancet Glob Health 2018 05;6(5):e579-e592
    International Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, UK.
    Background: Trachomatous trichiasis is treated surgically to prevent sight loss. Unfavourable surgical outcomes remain a major challenge. We investigated the hypothesis that doxycycline might reduce the risk of postoperative trichiasis following surgery in patients with trachomatous trichiasis through anti-matrix metalloproteinase and anti-inflammatory activity. Read More

    Chronic blepharitis like picture in patients with Discoid lupus erythematosis - Case series.
    Nepal J Ophthalmol 2017 Jul;9(18):175-179
    Background: Blepharitis is a very common condition encountered in ophthalmology outpatient care department. Dermatological diseases like seborrheic keratopathy and rosacea have been frequently discussed as being associated with blepharitis. However Discoid lupus erythematosis [DLE], an autoimmune condition has only rarely been reported to involve the eyelids mimicking blepharitis. Read More

    Clinical signs of trachoma are prevalent among Solomon Islanders who have no persistent markers of prior infection with .
    Wellcome Open Res 2018 22;3:14. Epub 2018 Feb 22.
    Clinical Research Department, London School of Hygiene & Tropical Medicine, London, UK.
    The low population-prevalence of trachomatous trichiasis and high prevalence of trachomatous inflammation-follicular (TF) provide contradictory estimates of the magnitude of the public health threat from trachoma in the Solomon Islands. Improved characterisation of the biology of trachoma in the region may support policy makers as they decide what interventions are required. Here, age-specific profiles of anti-Pgp3 antibodies and conjunctival scarring were examined to determine whether there is evidence of ongoing transmission and pathology from ocular infection. Read More

    Ophthalmologic Complications Associated With Oculofacial Plastic and Esthetic Surgeries.
    J Craniofac Surg 2018 Mar 16. Epub 2018 Mar 16.
    Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University College of Medicine.
    Purpose: To assess the ophthalmologic complications after oculofacial plastic and esthetic surgeries, including their incidence and management.

    Methods: A retrospective study was performed on 110 patients who presented with ocular complications followed by oculofacial plastic and esthetic surgeries from January 2014 to December 2015. The incidence and management of complications after each surgery or procedure were analyzed. Read More

    Anterior tarsal flap rotation combined with anterior lamellar reposition in the repair of cicatricial upper eyelid entropion.
    Arq Bras Oftalmol 2018 Jan-Feb;81(1):47-52
    Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.
    Purpose: This study aimed to share the results of patients who underwent anterior tarsal flap rotation combined with anterior lamellar reposition because of cicatricial upper eyelid entropion, and to determine the effectiveness and reliability of this surgical technique.

    Methods: Fifteen eyes of 11 patients (2 right eyes; 5 left eyes; and 4 bilateral eyes) on whom we performed anterior tarsal flap rotation surgery combined with anterior lamellar reposition because of cicatricial entropion were included in this study. The medical records of the patients were analyzed retrospectively, and the causes of cicatricial entropion as well as the preoperative and postoperative ophthalmic examination findings were recorded. Read More

    Anterior segment and external ocular disorders associated with HIV infections in the era of HAART in Chiang Mai University Hospital, a prospective descriptive cross sectional study.
    PLoS One 2018 21;13(2):e0193161. Epub 2018 Feb 21.
    Ophthalmology department, Chiang Mai University Hospital, Chiang Mai, Thailand.
    Human immunodeficiency virus (HIV) causes impairment to the human immune system which leads to immunocompromised conditions, including ocular complications. Several important HIV-associated disorders may involve the anterior segment, ocular surface, and adnexae organ such as dry eye, blepharitis which reduce quality of life of patients. In present, potent antiretroviral therapies HAART (highly active antiretroviral therapy) has improved the length and quality of life which may lead to an increased prevalence of anterior segment ocular disorders. Read More

    Prevalence of trachoma in the Kayes region of Mali eight years after stopping mass drug administration.
    PLoS Negl Trop Dis 2018 Feb 12;12(2):e0006289. Epub 2018 Feb 12.
    Regional Office for Africa, Helen Keller International, Dakar, Senegal.
    Background: In 2009, three years after stopping mass treatment with azithromycin, a trachoma impact survey in four health districts in the Kayes region of Mali found a prevalence of trachomatous inflammation-follicular (TF) among children aged 1 to 9 years of >5% and a trachomatous trichiasis (TT) prevalence within the general population (≥1-year-old) of <1%. As a result, the government's national trachoma program expanded trichiasis surgery and related activities required to achieve trachoma elimination.

    Methodology/principal Findings: In 2015, to assess progress towards elimination, a follow-up impact survey was conducted in the Kayes, Kéniéba, Nioro and Yélimané health districts. Read More

    Localized Trichiasis Causing Focal Full-Thickness Corneal Edema, Endothelial Cell Loss, and Corneal Scarring Requiring Penetrating Keratoplasty.
    Middle East Afr J Ophthalmol 2017 Oct-Dec;24(4):216-218
    Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, USA.
    The purpose of the study was to report a case of focal trichiasis causing full-thickness corneal edema, scarring, and endothelial cell loss requiring penetrating keratoplasty (PK). A 66-year-old male was referred for trichiasis of the right upper eyelid corresponding to an area of full-thickness corneal edema. No keratic precipitates or guttata was noted. Read More

    Interlamellar Autogenous Tarsal Graft for the Correction of Lower Eyelid Trichiasis Associated With Eyelid Margin Thinning.
    Ophthalmic Plast Reconstr Surg 2018 Jan 25. Epub 2018 Jan 25.
    Division of Oculoplastic and Orbit, Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, School of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
    Purpose: To evaluate the use of autogenous tarsal graft for surgical correction of lower eyelid trichiasis associated with eyelid thinning.

    Methods: A total of 23 eyelids of 19 consecutive patients with trichiasis were operated with a variant of the Van Millingen procedure. The surgery consisted of interposing a 3-mm high fragment of autogenous ipsilateral upper eyelid tarsus corresponding to the trichiasis segment between the pretarsal anterior lamella and the lower tarsal plate. Read More

    Ophthalmic examination findings and intraocular pressures in wild-caught African giant pouched rats (Cricetomys spp.).
    Vet Ophthalmol 2017 Dec 18. Epub 2017 Dec 18.
    Department of Psychology, Cornell University, Ithaca, NY, USA.
    Purpose: To report ophthalmic examination findings and intraocular pressures (IOPs) in wild-caught African giant pouched rats (Cricetomys ansorgei and gambianus) from Tanzania and Ghana.

    Procedures: After being placed under general anesthesia for examination, slit-lamp biomicroscopy before and after pharmacologic mydriasis and indirect ophthalmoscopy was performed. Eyes were fluorescein stained and IOPs measured by rebound tonometry using the TonoVet . Read More

    Elimination of trachoma as a public health problem in Ghana: Providing evidence through a pre-validation survey.
    PLoS Negl Trop Dis 2017 12 12;11(12):e0006099. Epub 2017 Dec 12.
    Neglected Tropical Diseases Program, Ghana Health Service, Accra, Ghana.
    Background: In order to achieve elimination of trachoma, a country needs to demonstrate that the elimination prevalence thresholds have been achieved and then sustained for at least a two-year period. Ghana achieved the thresholds in 2008, and since 2011 has been implementing its trachoma surveillance strategy, which includes community and school screening for signs of follicular trachoma and trichiasis, in trachoma-endemic districts. In 2015-2016, the country conducted a district level population-based survey to validate elimination of trachoma as a public health problem. Read More

    Retroseptal transconjunctival approach for fractures of the zygomaticomaxillary complex: a retrospective study.
    Br J Oral Maxillofac Surg 2018 Jan 29;56(1):29-33. Epub 2017 Nov 29.
    Dept of Preventive & Social Medicine, Armed Forces Medical College, Pune, India.
    We designed a retrospective study to evaluate the efficacy of retroseptal transconjunctival approaches in the management of fractures of the zygomaticomaxillary complex (ZMC). The patients were from a single institution, and had had three-point fixation of fractures of the ZMC between 2008 and 2016. A total of 77 patients (56 men and 21 women with a mean (range) age of 28 (18-54) years), were divided into two groups. Read More

    Impact of trichiasis surgery on daily living: A longitudinal study in Ethiopia.
    Wellcome Open Res 2017 22;2:69. Epub 2017 Aug 22.
    International Centre for Eye Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
    Trachomatous trichiasis (TT) may lead to disability, impeding productive activities, resulting in loss of income. This study was conducted to determine if trichiasis surgery improves participation in productive and leisure activities, and ability to perform activities without difficulty or assistance. We recruited 1000 adults with trichiasis (cases) and 200 comparison participants, matched to every fifth trichiasis case on age (+/- two years), sex and location. Read More

    Association of Human Leukocyte Antigen Class 1 genes with Stevens Johnson Syndrome with severe ocular complications in an Indian population.
    Sci Rep 2017 Nov 21;7(1):15960. Epub 2017 Nov 21.
    Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
    Stevens Johnson syndrome (SJS) is part of a spectrum of adverse drug reactions resulting in the destruction of skin, mucous membranes, and the ocular surface. A similar, more severe form of the disorder included in this spectrum is toxic epidermal necrolysis (TEN). Approximately 35% of patients suffer chronic sequelae such as vascularization, corneal scarring, conjunctival inversion to the cornea, keratinization, symblepharon, scarring of the palpebral conjunctiva, trichiasis, and severe dry eye. Read More

    Randomized double-masked trial of eyelid cleansing treatments for blepharitis.
    Ocul Surf 2018 Jan 8;16(1):77-83. Epub 2017 Nov 8.
    Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address:
    Purpose: To compare the efficacy of a dedicated eyelid cleanser and diluted baby shampoo in the management of blepharitis.

    Methods: Forty-three participants with clinical blepharitis signs were enrolled in a prospective, randomized, double-masked, paired-eye trial. A dedicated eyelid cleanser (TheraTears SteriLid) was applied to the eyelids of one eye (randomized) and diluted baby shampoo (Johnson's No More Tears) to the fellow eye, twice daily for 4 weeks. Read More

    Ocular features of multiple system atrophy.
    J Clin Neurosci 2018 Jan 21;47:234-239. Epub 2017 Oct 21.
    Department of Ophthalmology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA; Department of Neurology, Mayo Clinic, 200 First Street, SW, Rochester, MN 55905, USA. Electronic address:
    The aim of this paper is to gain better understanding of the ocular manifestations of multiple system atrophy (MSA), a neurodegenerative disorder rarely studied in terms of its ophthalmologic features. We performed a retrospective case series (1/1/05-12/31/14) to search for patients seen at Mayo Clinic, Rochester, MN, who had mention of MSA in the medical record and an eye examination, which yielded 285 cases. Of the 285, we identified 39 cases of true MSA. Read More

    Surveillance Surveys for Reemergent Trachoma in Formerly Endemic Districts in Nepal From 2 to 10 Years After Mass Drug Administration Cessation.
    JAMA Ophthalmol 2017 Nov;135(11):1141-1146
    Research Triangle Institute (RTI) International, Washington, DC.
    Importance: To verify districts for elimination of blinding trachoma, the World Health Organization requires a population-based surveillance survey for follicular trachoma (TF) and trachomatous trichiasis (TT) 2 years after mass drug administration (MDA) activities have ceased. However, it is unknown if 2 years provides enough time to discover reemergence.

    Objective: To determine the prevalence of trachoma from surveys among 4 districts in Nepal (Dailekh, Dang, Surkhet, and Kanchanpur) that had surveillance intervals of 2, 4, 8, and 10 years, respectively, after cessation of MDA. Read More

    Temporal horizontal H-figure sliding skin flap for central eyelid reconstructive surgery in dogs: a retrospective study.
    J Small Anim Pract 2017 Dec 25;58(12):709-713. Epub 2017 Sep 25.
    Department of Veterinary Sciences, University of Pisa, Via Livornese (lato monte), 56122 San Piero a Grado, Pisa, Italy.
    Objective: To describe a modified H-figure sliding skin flap for treating eyelid central neoplasms and to evaluate the cosmetic and functional results of this reconstructive blepharoplasty.

    Material And Methods: Eight dogs affected by eyelid neoplasia involving more than one-third of the central part of the margin underwent an en bloc rectangular surgical removal of the neoplasia. Reconstructive surgery was performed using a temporal horizontal H-figure sliding skin flap. Read More

    The Epidemiology of Trachoma in Mozambique: Results of 96 Population-Based Prevalence Surveys.
    Ophthalmic Epidemiol 2017 Sep 14:1-10. Epub 2017 Sep 14.
    l Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: Surveys are needed to guide trachoma control efforts in Mozambique, with WHO guidelines for intervention based on the prevalence of trachomatous inflammation-follicular (TF) in children aged 1-9 years and the prevalence of trichiasis in adults aged 15 years and above. We conducted surveys to complete the map of trachoma prevalence in Mozambique.

    Methods: Between July 2012 and May 2015, we carried out cross-sectional surveys in 96 evaluation units (EUs) covering 137 districts. Read More

    Prevalence of signs of trachoma, ocular Chlamydia trachomatis infection and antibodies to Pgp3 in residents of Kiritimati Island, Kiribati.
    PLoS Negl Trop Dis 2017 Sep 12;11(9):e0005863. Epub 2017 Sep 12.
    Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.
    Objective: In some Pacific Island countries, such as Solomon Islands and Fiji, active trachoma is common, but ocular Chlamydia trachomatis (Ct) infection and trachomatous trichiasis (TT) are rare. On Tarawa, the most populous Kiribati island, both the active trachoma sign "trachomatous inflammation-follicular" (TF) and TT are present at prevalences warranting intervention. We sought to estimate prevalences of TF, TT, ocular Ct infection, and anti-Ct antibodies on Kiritimati Island, Kiribati, to assess local relationships between these parameters, and to help determine the need for interventions against trachoma on Kiribati islands other than Tarawa. Read More

    Outcomes of two surgical techniques for major trichiasis treatment.
    Orbit 2018 Feb 30;37(1):36-40. Epub 2017 Aug 30.
    a Faculdade de Medicina de Botucatu , Universidade Estadual Paulista , Botucatu, Sao Paulo State , Brazil.
    The purpose of this article is to analyze the outcomes of two surgical techniques to treat major trichiasis. A retrospective chart review of 67 patients (89 eyelids) with major trichiasis was performed who underwent surgical treatment using one of two techniques: intermarginal split lamella with graft (ISLG group) or lid lamella resection (LLR group). There were 30 lids in the ISLG group with mean patient age of 71. Read More

    Trachoma in the Democratic Republic of the Congo: Results of 46 Baseline Prevalence Surveys Conducted with the Global Trachoma Mapping Project.
    Ophthalmic Epidemiol 2017 Aug 29:1-9. Epub 2017 Aug 29.
    k Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: Trachoma was suspected to be endemic in parts of the Democratic Republic of the Congo (DRC). We aimed to estimate prevalences of trachomatous inflammation-follicular (TF), trichiasis, and water and sanitation (WASH) indicators in suspected-endemic Health Zones.

    Methods: A population-based prevalence survey was undertaken in each of 46 Health Zones across nine provinces of DRC, using Global Trachoma Mapping Project methods. Read More

    Use of validated community-based trachoma trichiasis (TT) case finders to measure the total backlog and detect when elimination threshold is achieved: a TT methodology paper.
    Pan Afr Med J 2017 5;27:84. Epub 2017 Jun 5.
    Narok County Government, Narok, Kenya.
    Introduction: The World Health Organization recommends TT surveys to be conducted in adults aged 15+ years (TT 15 survey) and certifies elimination of TT as a public health problem when there is less than 1 unknown case per 1,000 people of all ages. There is no standard survey method to accurately confirm this elimination prevalence threshold of 0.1% because rare conditions require large and expensive prevalence survey samples. Read More

    Treatment of Children With Congenital Severe Blepharoptosis by Frontalis Aponeurosis Flap Advancement Under General Anesthesia in a Single Incision.
    J Craniofac Surg 2017 Sep;28(6):1495-1497
    Plastic Surgery Department, Children's Hospital of Fudan University, Shanghai, China.
    Purpose: This study aimed to investigate the effect of frontalis aponeurosis flap advancement in children with congenital severe blepharoptosis.

    Methods: A total of 23 cases (25 eyes) of children who had congenital severe blepharoptosis and poor levator function (≤4 mm) and received frontalis aponeurosis flap advancement treatment in the Plastic Surgery Department of the Children's Hospital of Fudan University from January 1, 2013, to January 1, 2015, were retrospectively analyzed to evaluate the postoperative effects.

    Results: All patients (age range, 6-27 months) were followed up for an average duration of 15. Read More

    Population-based prevalence survey of follicular trachoma and trachomatous trichiasis in the Casamance region of Senegal.
    BMC Public Health 2017 07 26;18(1):62. Epub 2017 Jul 26.
    Department of Clinical Research, London School of Hygiene & Tropical Medicine, London, UK.
    Background: Trachoma, caused by ocular infection with Chlamydia trachomatis, is the leading infectious cause of blindness worldwide. We conducted the first population-based trachoma prevalence survey in the Casamance region of Senegal to enable the Senegalese National Eye Care Programme (NECP) to plan its trachoma control activities. The World Health Organization (WHO) guidelines state that any individual with trachomatous trichiasis (TT) should be offered surgery, but that surgery should be prioritised where the prevalence is >0. Read More

    Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys.
    PLoS Negl Trop Dis 2017 Jun 14;11(6):e0005658. Epub 2017 Jun 14.
    Trachoma Control Program, The Carter Center, Atlanta, Georgia, United States of America.
    Background: In order to decrease the prevalence of trachoma within the country, the Republic of South Sudan has implemented components of the SAFE strategy in various counties since 2001. Five counties in Eastern Equatoria state were surveyed in order to monitor progress of programmatic interventions and determine if additional rounds of Mass Drug Administration with azithromycin were needed.

    Methodology/ Principal Findings: Five counties (Budi, Lafon, Kapoeta East, Kapoeta South and Kapoeta North) were surveyed from April to October 2015. Read More

    Prevalence of trachomatous trichiasis in Australia: the National Eye Health Survey.
    Clin Exp Ophthalmol 2018 Jan 9;46(1):13-17. Epub 2017 Aug 9.
    Indigenous Eye Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia.
    Importance: Australia is the only developed country to still have pockets of endemic trachoma. The research provides up-to-date, population-based prevalence data of later complications of trachoma amongst a national sample of Indigenous adults.

    Background: To report the prevalence of trachomatous trichiasis (TT) in Indigenous Australians aged 40 years and older. Read More

    [Anterior lamellar resection with lid margin split of the upper eyelid in the treatment of trachomatous entropion].
    J Fr Ophtalmol 2017 Jun 31;40(6):453-459. Epub 2017 May 31.
    Service d'ophtalmologie adulte, hôpital 20-Août-1953, CHU Ibn Rochd, quartier des hôpitaux, Casablanca, Maroc.
    Introduction: The goal of this study is to assess functional and aesthetic results of anterior lamellar resection with lid margin splitting of the upper lid in the treatment of cicatricial trachomatous entropion.

    Patients And Methods: Descriptive cross-sectional study of a series of 26 consecutive patients treated between January 2014 and December 2015. All patients were operated for cicatricial trachomatous entropion in our tertiary center using the technique of the anterior lamellar resection with lid margin splitting of the upper eyelid. Read More

    Utility of PROSE Device in the Management of Complex Oculoplastic Pathology.
    Ophthalmic Plast Reconstr Surg 2018 May/Jun;34(3):242-245
    Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University, New York, New York, U.S.A.
    Purpose: To describe the use of Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) device in the management of complex oculoplastic pathology.

    Methods: The authors retrospectively reviewed the records of individuals over 18 years of age who were referred and successfully fit with the PROSE scleral device between January 1995 and June 2015.

    Results: Nine cases were identified that had complex oculoplastic disease and severe corneal surface disease. Read More

    Scleral Contact Lenses in an Academic Oculoplastics Clinic: Epidemiology and Emerging Considerations.
    Ophthalmic Plast Reconstr Surg 2018 May/Jun;34(3):231-236
    Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinic, Iowa City, Iowa.
    Purpose: To describe the role and efficacy of scleral contact lenses (SCLs) in the treatment of progressive keratopathy in patients who have undergone periocular surgical procedures, to investigate the financial impact of these surgical interventions, and to demonstrate the role of oculoplastic surgery in improving scleral contact lens fit.

    Methods: A retrospective medical record review was performed to identify patients who both received SCLs and were examined by the oculoplastics service at the University of Iowa between January 1990 and December 2015. Inclusion criteria also required a minimum of 12 months of patient follow up after being fit with a SCL. Read More

    The Burden of and Risk Factors for Trachoma in Selected Districts of Zimbabwe: Results of 16 Population-Based Prevalence Surveys.
    Ophthalmic Epidemiol 2017 May 22:1-11. Epub 2017 May 22.
    b Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Background: Trachoma, a leading cause of blindness, is targeted for global elimination as a public health problem by 2020. In order to contribute to this goal, countries should demonstrate reduction of disease prevalence below specified thresholds, after implementation of the SAFE strategy in areas with defined endemicity. Zimbabwe had not yet generated data on trachoma endemicity and no specific interventions against trachoma have yet been implemented. Read More

    Prevalence of Trachoma in Northern Benin: Results from 11 Population-Based Prevalence Surveys Covering 26 Districts.
    Ophthalmic Epidemiol 2017 08 25;24(4):265-273. Epub 2017 Apr 25.
    a National Control Program of Communicable Diseases, Ministry of Health , Benin.
    Aims: We sought to evaluate trachoma prevalence in all suspected-endemic areas of Benin.

    Methods: We conducted population-based surveys covering 26 districts grouped into 11 evaluation units (EUs), using a two-stage, systematic and random, cluster sampling design powered at EU level. In each EU, 23 villages were systematically selected with population proportional to size; 30 households were selected from each village using compact segment sampling. Read More

    Predictors of Trachomatous Trichiasis Surgery Outcome.
    Ophthalmology 2017 08 21;124(8):1143-1155. Epub 2017 Apr 21.
    London School of Hygiene and Tropical Medicine, London, United Kingdom.
    Purpose: Unfavorable outcomes after trachomatous trichiasis (TT) surgery are undermining the global trachoma elimination effort. This analysis investigates predictors of postoperative TT (PTT), eyelid contour abnormalities (ECAs), and granuloma in the 2 most common TT surgery procedures: posterior lamellar tarsal rotation (PLTR) and bilamellar tarsal rotation (BLTR).

    Design: Secondary data analysis from a randomized, controlled, single-masked clinical trial. Read More

    Chlamydial eye infections: Current perspectives.
    Indian J Ophthalmol 2017 Feb;65(2):97-102
    Section of Ocular Microbiology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
    Chlamydia trachomatis, an obligate intraocular bacteria causing trachoma, adult and neonatal inclusion conjunctivitis, was the leading cause of blindness in the last century worldwide. Improvement in socioeconomic and living conditions, availability of antibiotics, and introduction of National Trachoma Control Programmes reduced the prevalence in developed countries, but it persisted in resource-poor settings of Africa and Asia, including India. In 2016, as per the WHO report, trachoma is restricted to 42 countries, causing blindness/visual impairment in ~1. Read More

    Profiling and validation of individual and patterns of Chlamydia trachomatis-specific antibody responses in trachomatous trichiasis.
    Parasit Vectors 2017 Mar 13;10(1):143. Epub 2017 Mar 13.
    Clinical Research Department, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
    Background: Ocular Chlamydia trachomatis (Ct) infection causes trachoma, the leading infectious cause of blindness. A Ct D/UW3 proteome microarray and sera from Gambian adults with trachomatous trichiasis (TT) or healthy matched controls previously identified several novel antigens, which suggested differential recognition in adults with TT.

    Methods: We re-analysed this serological microarray data using more robust microarray analysis techniques accounting for typical problems associated with highly dimensional data. Read More

    Prevalence of Trachoma in Kano State, Nigeria: Results of 44 Local Government Area-Level Surveys.
    Ophthalmic Epidemiol 2017 06 28;24(3):195-203. Epub 2017 Feb 28.
    l Department of Control of Neglected Tropical Diseases , World Health Organization , Geneva , Switzerland.
    Purpose: We sought to determine the prevalence of trachoma in 44 Local Government Areas (LGAs) of Kano State, Nigeria.

    Methods: A population-based prevalence survey was conducted in each Kano LGA. We used a two-stage systematic and quasi-random sampling strategy to select 25 households from each of 25 clusters in each LGA. Read More

    Podoconiosis, trachomatous trichiasis and cataract in northern Ethiopia: A comparative cross sectional study.
    PLoS Negl Trop Dis 2017 Feb 10;11(2):e0005388. Epub 2017 Feb 10.
    Wellcome Trust Brighton and Sussex Centre for Global Health Research, Brighton and Sussex Medical School, Brighton, United Kingdom.
    Background: Rural populations in low-income countries commonly suffer from the co-morbidity of neglected tropical diseases (NTDs). Podoconiosis, trachomatous trichiasis (both NTDs) and cataract are common causes of morbidity among subsistence farmers in the highlands of northern Ethiopia. We explored whether podoconiosis was associated with cataract or trachomatous trichiasis (TT) among this population. Read More

    Long-term outcome of allogeneic cultivated limbal epithelial transplantation for symblepharon caused by severe ocular burns.
    BMC Ophthalmol 2017 Jan 31;17(1). Epub 2017 Jan 31.
    State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Shandong Eye Institute, Shandong Academy of Medical Sciences, 5 Yanerdao Road, 266071, Qingdao, China.
    Background: The therapeutic effects of allogeneic cultivated limbal epithelial transplantation (CLET) for symblephara at different degrees caused by ocular burns were evaluated in this study.

    Methods: A series of interventional cases were involved in this retrospective study. Eighty eyes (80 patients) with symblephara underwent CLET and the success rates of surgical treatment as well as corneal conditions and risk factors for recurrent symblepharon were analyzed. Read More

    Eyelash Epilation in the Absence of Trichiasis: Results of a Population-Based Prevalence Survey in the Western Division of Fiji.
    PLoS Negl Trop Dis 2017 Jan 23;11(1):e0005277. Epub 2017 Jan 23.
    Clinical Research Department, London School of Hygiene & Tropical Medicine, London, United Kingdom.
    Background: The WHO definition of trachomatous trichiasis (TT) is "at least one eyelash touching the globe, or evidence of recent epilation of in-turned eyelashes", reflecting the fact that epilation is used as a self-management tool for TT. In Fiji's Western Division, a high TT prevalence (8.7% in those aged ≥15 years) was reported in a 2012 survey, yet a 2013 survey found no TT and Fijian ophthalmologists rarely see TT cases. Read More

    Delivery of Eye and Vision Services in Aboriginal and Torres Strait Islander Primary Healthcare Centers.
    Front Public Health 2016 19;4:276. Epub 2016 Dec 19.
    Menzies School of Health Research, Charles Darwin University , Brisbane, QLD , Australia.
    Background: Routine eye and vision assessments are vital for the detection and subsequent management of vision loss, which is particularly important for Aboriginal and Torres Strait Islander people who face higher rates of vision loss than other Australians. In order to guide improvements, this paper will describe patterns, variations, and gaps in these eye and vision assessments for Aboriginal and Torres Strait Islander people.

    Methods: Clinical audits from 124 primary healthcare centers (sample size 15,175) from five Australian states and territories were conducted during 2005-2012. Read More

    Identifying Patient Perceived Barriers to Trichiasis Surgery in Kongwa District, Tanzania.
    PLoS Negl Trop Dis 2017 Jan 4;11(1):e0005211. Epub 2017 Jan 4.
    Dana Center for Preventive Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.
    Background: Trachomatous trichiasis (TT), inturned eyelashes from repeated infection with Chlamydia trachomatis, is the leading infectious cause of blindness in the world. Though surgery will correct entropion caused by trachoma, uptake of TT surgery remains low. In this case-control study, we identify barriers that prevent TT patients from receiving sight-saving surgery. Read More

    Mapping Trachoma in the Solomon Islands: Results of Three Baseline Population-Based Prevalence Surveys Conducted with the Global Trachoma Mapping Project.
    Ophthalmic Epidemiol 2016 12;23(sup1):15-21. Epub 2016 Dec 12.
    b Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: We sought to complete the baseline trachoma map of the Solomon Islands by establishing prevalences of active trachoma and trichiasis in the provinces of Choiseul, Western, Rennell-Bellona, and Temotu.

    Methods: Using the standardized methodology developed for the Global Trachoma Mapping Project, we conducted cross-sectional community-based surveys from September to November 2013. Choiseul and Western provinces were each mapped as separate evaluation units (EUs); Rennell-Bellona and Temotu were combined to form a third EU. Read More

    Prevalence of Trachoma in Benishangul Gumuz Region, Ethiopia: Results of Seven Population-Based Surveys from the Global Trachoma Mapping Project.
    Ophthalmic Epidemiol 2016 5;23(sup1):70-76. Epub 2016 Dec 5.
    b Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: Trachoma is a major cause of blindness in Ethiopia, and targeted for elimination as a public health problem by the year 2020. Prevalence data are needed to plan interventions. We set out to estimate the prevalence of trachoma in each evaluation unit of grouped districts ("woredas") in Benishangul Gumuz region, Ethiopia. Read More

    The Prevalence of Trachoma in Tigray Region, Northern Ethiopia: Results of 11 Population-Based Prevalence Surveys Completed as Part of the Global Trachoma Mapping Project.
    Ophthalmic Epidemiol 2016 5;23(sup1):94-99. Epub 2016 Dec 5.
    c Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: We aimed to estimate the prevalence of trachoma in each district ("woreda") of Tigray Region, Ethiopia.

    Methods: We conducted 11 cross-sectional community-based surveys in evaluation units covering 34 rural woredas from January to March 2013 using the standardized methodology developed for the Global Trachoma Mapping Project.

    Results: Teams visited 8034 households in 275 villages. Read More

    Prevalence of and Risk Factors for Trachoma in Southern Nations, Nationalities, and Peoples' Region, Ethiopia: Results of 40 Population-Based Prevalence Surveys Carried Out with the Global Trachoma Mapping Project.
    Ophthalmic Epidemiol 2016 5;23(sup1):84-93. Epub 2016 Dec 5.
    b Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Purpose: We sought to estimate the prevalence of trachoma at sufficiently fine resolution to allow elimination interventions to begin, where required, in the Southern Nations, Nationalities, and Peoples' Region (SNNPR) of Ethiopia.

    Methods: We carried out cross-sectional population-based surveys in 14 rural zones. A 2-stage cluster randomized sampling technique was used. Read More

    Mapping Trachoma in Kaduna State, Nigeria: Results of 23 Local Government Area-Level, Population-Based Prevalence Surveys.
    Ophthalmic Epidemiol 2016 5;23(sup1):46-54. Epub 2016 Dec 5.
    k Clinical Research Department , London School of Hygiene & Tropical Medicine , London , UK.
    Introduction: To prepare for global elimination of trachoma by 2020, the World Health Organization (WHO) recommends mapping of trachoma at district-level to enable planning of elimination activities in affected populations. The aim of our study was to provide data on trachoma for each local government area (LGA) of Kaduna State, Nigeria, as such data were previously unavailable.

    Method: As part of the Global Trachoma Mapping Project (GTMP), a population-based cross-sectional trachoma survey was conducted in each of the 23 LGAs of Kaduna State, between May and June 2013. Read More

    1 OF 16