359 results match your criteria Trench Fever

Bartonella quintana Infection in People Experiencing Homelessness in the Denver Metropolitan Area.

J Infect Dis 2022 Jun 24. Epub 2022 Jun 24.

Division of Infectious Diseases, University of Colorado Anschutz Medical Campus, Aurora, Colorado, U.S.A.

Background: Bartonella quintana is an important cause of infection amongst people experiencing homelessness that is underdiagnosed due to its non-specific clinical manifestations. We reviewed cases identified in the Denver Metropolitan Area from 2016-2021.

Methods: The electronic medical records from two large academic medical centers in Colorado were reviewed for demographic, clinical, and laboratory features of patients with B. Read More

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Detection of subsp. in a HIV patient using metagenomic Next Generation Sequencing.

Emerg Microbes Infect 2022 Jun 23:1-9. Epub 2022 Jun 23.

Infection hospital area of the First Affiliated Hospital of University of science and technology of China, Hefei, China.

Bartonella are fastidious, aerobic bacteria that are transmitted by blood-sucking arthropods. spp. are responsible for cat scratch disease, Carrion's disease, bacillary angiomatosis and trench fever. Read More

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Bartonella quintana endocarditis in a child from Northern Manitoba, Canada.

PLoS Negl Trop Dis 2022 05 26;16(5):e0010399. Epub 2022 May 26.

University of Manitoba, Winnipeg, Manitoba, Canada.

We describe a case of Bartonella quintana endocarditis in an 11-year-old child from Northern Manitoba, Canada. This case demonstrates the neglected endemicity of B. quintana in Northern Canada and highlights the need for improved case finding and elucidation of specific risk factors for B. Read More

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The Passenger Domain of Bartonella bacilliformis BafA Promotes Endothelial Cell Angiogenesis via the VEGF Receptor Signaling Pathway.

mSphere 2022 04 5;7(2):e0008122. Epub 2022 Apr 5.

Department of Microbiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan.

Bartonella bacilliformis is a Gram-negative bacterial pathogen that provokes pathological angiogenesis and causes Carrion's disease, a neglected tropical disease restricted to South America. Little is known about how facilitates vasoproliferation resulting in hemangioma in the skin in verruga peruana, the chronic phase of Carrion's disease. Here, we demonstrate that extracellularly secrets a passenger domain of the autotransporter BafA exhibiting proangiogenic activity. Read More

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Bartonella endocarditis in patients with right ventricle-to-pulmonary artery conduit: 2 case reports and literature review.

IDCases 2021 11;26:e01306. Epub 2021 Oct 11.

Department of Pediatrics and Adolescent Medicine, Western Michigan University Homer Stryker MD School of Medicine, 1000 Oakland Dr, Kalamazoo, MI 49008, USA.

species are Gram-negative bacilli and fastidious bacteria that can cause a number of clinical syndromes, including blood culture-negative infective endocarditis (IE). The two most commonly isolated species in humans are the agent of trench fever, and mostly known for causing cat scratch disease (Edouard et al., 2015 [1]; Edouard and Raoult, 2010 [2]). Read More

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October 2021

[Recurrent intracerebral haemorrhage in a 24-year-old female patient].

Internist (Berl) 2022 Jan 29;63(1):103-109. Epub 2021 Sep 29.

Medizinische Klinik - Innere Medizin, Klinikum Füssen, Kliniken Ostallgäu-Kaufbeuren, Stadtbleiche 1, 87629, Füssen, Deutschland.

A 24-year-old female patient from Sierra Leone was referred to the authors' hospital after several unclear intracerebral bleeding events and an echogenic structure on the aortic valve. The patient was receiving oral anticoagulation therapy due to paroxysmal atrial fibrillation and left ventricular noncompaction. Fluorescence in situ hybridization in combination with polymerase chain reaction and sequencing revealed infective endocarditis of the mitral and aortic valve caused by Bartonella quintana. Read More

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January 2022

Cat Scratch Disease and Bartonellaceae: The Known, the Unknown and the Curious.

Pediatr Infect Dis J 2021 05;40(5S):S11-S15

From the Division of Pediatric Infectious Diseases, Harbor-UCLA Medical Center, Los Angeles, California.

Since the early 1900s, Bartonella species were known only to cause human disease resulting from very restricted geographic (bartonellosis) or environmental influences ("trench fever"). In the 1990s, and in parallel, cat scratch disease and bacillary angiomatosis were definitively linked to Bartonella species. Subsequently, widespread use of modern diagnostic methods revealed the broad ecologic niche of this organism and greatly expanded our knowledge of the epidemiology and clinical presentations associated with this genus. Read More

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Detection of Bartonella sp. in ticks and their small mammal hosts in mangrove forests of Peninsular Malaysia.

Trop Biomed 2020 Dec;37(4):919-931

Department of Biological Sciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 UKM Bangi, Selangor, Malaysia.

Bacteria of the genus Bartonella have been known as emerging zoonotic pathogens for several human diseases including cat scratch disease, Carrion's disease and trench fever. Numerous species of small mammals have been reported to play a role as a suitable reservoir to many pathogenic Bartonella. These infections are thought to be transmitted through blood-feeding arthropod vectors such as ticks, fleas and lice. Read More

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December 2020

Human dental pulp stem cells: A sanctuary for relapsing Bartonella quintana.

Microb Pathog 2021 Apr 18;153:104797. Epub 2021 Feb 18.

Institut Hospitalier Universitaire Méditerranée Infection, Marseille, France; Aix-Marseille-Université, IRD, MEPHI, IHU Méditerranée Infection, Marseille, France. Electronic address:

Bartonella quintana is a facultative intracellular bacterium responsible for relapsing fever, an example of non-sterilizing immunity. The cellular sanctuary of B. quintana in-between febrile relapses remains unknown but repeated detection of B. Read More

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Detection of Bartonella quintana Infection among the Homeless Population in Tokyo, Japan, from 2013-2015.

Jpn J Infect Dis 2021 Sep 29;74(5):411-415. Epub 2021 Jan 29.

Department of Medical Entomology, National Institute of Infectious Diseases, Japan.

Several outbreaks of trench fever caused by Bartonella quintana occurred in soldiers during World Wars I and II. Although trench fever cases have been decreasing worldwide, the disease was reported among the homeless population in developing and developed countries. The current prevalence of B. Read More

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September 2021

What's eating you? human flea (Pulex irritans).

Cutis 2020 Nov;106(5):233-235

Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, USA.

The human flea, Pulex irritans, is an important vector in the transmission of human diseases. This flea has been identified as a vector for the bubonic plague as far back as the 14th century, causing millions of deaths. Pulex irritans also has been identified as a vector for Bartonella bacteria species, which can cause trench fever. Read More

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November 2020

Endocarditis due to , the etiological agent of trench fever.

CMAJ 2020 Dec;192(49):E1723-E1726

Section of Infectious Diseases (Boodman, Wuerz), Department of Internal Medicine and Departments of Medical Microbiology and Infectious Diseases (Boodman, Lagacé-Wiens) and Community Health Sciences (Wuerz), Max Rady College of Medicine, University of Manitoba; Shared Health (Lagacé-Wiens), Winnipeg, Man.

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December 2020

Five millennia of Bartonella quintana bacteraemia.

PLoS One 2020 4;15(11):e0239526. Epub 2020 Nov 4.

Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique-Hôpitaux de Marseille (AP-HM), Microbes, Evolution, Phylogeny and Infection (MEPHI), Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France.

During the two World Wars, Bartonella quintana was responsible for trench fever and is now recognised as an agent of re-emerging infection. Many reports have indicated widespread B. quintana exposure since the 1990s. Read More

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December 2020

Unusual subdural empyema in a homeless patient diagnosed by molecular approach: a case report.

BMC Infect Dis 2020 May 19;20(1):357. Epub 2020 May 19.

Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pierre-Louis d'Epidémiologie et de Santé Publique, Paris, France.

Background: We report a case of subdural empyema in a homeless patient caused by Bartonella quintana. B. quintana is a facultative intracellular bacteria for which bacterial growth is fastidious. Read More

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Endocarditis in a Homeless Man with Cat Exposure in San Diego, California.

Vector Borne Zoonotic Dis 2020 06 9;20(6):468-470. Epub 2020 Jan 9.

Division of Infectious Diseases and Global Public Health, UC San Diego Health Department of Medicine, San Diego, California, USA.

We report a case of endocarditis in a homeless man with congenital bicuspid aortic valve and significant cat exposure living in downtown San Diego, California. Read More

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Cutaneous manifestations of bartonellosis.

An Bras Dermatol 2019 Sep - Oct;94(5):594-602. Epub 2019 Oct 2.

Laboratory of Applied Research in Dermatology and Bartonella Infection, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil; Discipline of Dermatology, Department of Clinical Medicine, School of Medical Sciences, Universidade Estadual de Campinas, Campinas, SP, Brazil. Electronic address:

Bartonellosis are diseases caused by any kind of Bartonella species. The infection manifests as asymptomatic bacteremia to potentially fatal disorders. Many species are pathogenic to humans, but three are responsible for most clinical symptoms: Bartonella bacilliformis, Bartonella quintana, and Bartonella henselae. Read More

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December 2019

Molecular Detection of Dengue Virus in Mosquitoes as an Early Indicator to Aid in the Prevention of Human Infection in Endemic Areas.

Vector Borne Zoonotic Dis 2020 01 7;20(1):54-59. Epub 2019 Nov 7.

Department of Veterinary Medicine, Federal University of Paraná, Paraná, Brazil.

Human cases of dengue virus based on the National Dengue Control Plan were compared with the molecular detection of the dengue virus in trapped mosquitoes, verifying the prediction and efficacy potentials of vector control between the two methodologies in a city with three endemic frontiers. Molecular detection of dengue virus in trapped mosquitoes was significantly higher than in human cases ( = 0.0435). Read More

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January 2020

Endocarditis caused by , a rare case in the United States.

IDCases 2019 6;17:e00533. Epub 2019 Apr 6.

Division of Infectious Diseases, Indiana University School of Medicine, Indianapolis, IN, USA.

is a relatively rare cause of endocarditis in the United States (USA). Historically it was linked with trench fever, but cardiac involvement seems to be more prevalent recently. There are some known risk factors associated with endocarditis such as human immunodeficiency virus (HIV) infection, alcoholism, homelessness and poor hygiene. Read More

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Ectoparasites: Pediculosis and tungiasis.

J Am Acad Dermatol 2020 Mar 13;82(3):551-569. Epub 2019 Jul 13.

Department of Dermatology, University of California, San Francisco, San Francisco, California. Electronic address:

Pediculosis is an infestation of lice on the body, head, or pubic region that occurs worldwide. Lice are ectoparasites of the order Phthiraptera that feed on the blood of infested hosts. Their morphotype dictates their clinical features. Read More

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The seroprevalence of Bartonella spp. in the blood of patients with musculoskeletal complaints and blood donors, Poland: a pilot study.

Clin Rheumatol 2019 Oct 22;38(10):2691-2698. Epub 2019 May 22.

Department of Microbiology and Medical Laboratory Immunology, Medical University of Lodz, Pomorska 251, 92-231, Lodz, Poland.

Background: Bartonella spp. can cause a variety of diseases, such as lymphadenopathies, cat scratch disease, and trench fever, but can also give rise to many non-specific symptoms. No data exists regarding the prevalence of Bartonella spp. Read More

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October 2019

Infective Endocarditis Due to Bartonella Quintana in a Patient with Biological Aortic Prosthesis.

Rev Port Cir Cardiotorac Vasc 2019 Jan-Mar;26(1):59-61

Department of Cardiothoracic Surgery, Hospital de Santa Marta, Lisbon, Portugal.

Background: Bartonella quintana is a facultative intracellular bacterium and the causative agent of trench fever. The disease was reported during the World Wars in pre-antibiotic era and is associated with louse infestation and poor hygiene conditions. Bartonella bacteraemia may result in endocarditis mostly in people with existing heart valve abnormalities. Read More

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September 2019

A Case of Bartonella Quintana Culture-Negative Endocarditis.

Am J Case Rep 2019 Apr 26;20:602-606. Epub 2019 Apr 26.

Institute of Human Virology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.

BACKGROUND Culture-negative Bartonella quintana endocarditis is challenging to diagnose and is associated with high mortality rates. Diagnostic confirmation of Bartonella quintana infection requires specialized assays, as identifying Bartonella henselae endocarditis by serology can be difficult due to the high rate of serological cross-reactivity. This is a case report of culture-negative Bartonella quintana endocarditis that was diagnosed with epidemiologic data, histology, and nucleic acid amplification testing. Read More

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Bartonella henselae- and quintana-associated uveitis: a case series and approach of a potentially severe disease with a broad spectrum of ocular manifestations.

Int Ophthalmol 2019 Nov 9;39(11):2505-2515. Epub 2019 Mar 9.

Department of Ophthalmology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Stavros Niarchos Avenue, 45110, Ioannina, Greece.

Purpose: To evaluate the clinical manifestations of intraocular inflammation associated with Bartonella infection and describe the assessment and management of patients with cat-scratch disease (CSD).

Methods: This is a retrospective review of the clinical records of patients diagnosed with Bartonella henselae and Bartonella quintana intraocular inflammation from 2011 to 2018 in the Department of Ocular Inflammations and Infections of the University Eye Clinic of Ioannina (Greece). An analysis of the current literature concerning Bartonella-related intraocular infections was also carried out. Read More

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November 2019

Case Report: Endocarditis Outside of the Europe-African Gradient: Comprehensive Review of Cases within North America.

Am J Trop Med Hyg 2019 05;100(5):1125-1129

Department of Medicine, University of Calgary, Calgary, Canada.

Clinical syndromes associated with infection can be insidious and difficult to diagnose for multiple reasons. Clinically, can manifest as asymptomatic bacteremia or with subtle subacute constitutional symptoms. Second, it is a fastidious organism that is difficult to identify using traditional culture methods. Read More

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The impact of infectious disease in war time: a look back at WW1.

Hugh Pennington

Future Microbiol 2019 02 10;14:165-168. Epub 2019 Jan 10.

Emeritus Professor of Bacteriology, University of Aberdeen, 13 Carlton Place, Aberdeen AB15 4BR, UK.

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February 2019

Bartonella spp. Bloodstream Infection in a Canadian Family.

Vector Borne Zoonotic Dis 2019 04 27;19(4):234-241. Epub 2018 Dec 27.

1 Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Historically, Bartonella spp. have been associated with febrile illness (Oroya fever, trench fever, and cat scratch disease), endocarditis (numerous Bartonella spp.), and vasoproliferative lesions (Bartonella bacilliformis, Bartonella quintana, Bartonella henselae, and Bartonella vinsonii subsp. Read More

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Bartonella quintana, past, present, and future of the scourge of World War I.

Joaquim Ruiz

APMIS 2018 Nov;126(11):831-837

Independent Researcher, Barcelona, Spain.

During World War I, a mysterious new disease affected soldiers on both sides of battle field. The first reports described a relapsing fever of unknown origin with body lice being suggested as the vector. The outbreak affected >1 000 000 people, mostly soldiers fighting in front-line trenches. Read More

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November 2018

Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs.

J Vet Intern Med 2018 Nov 11;32(6):1958-1964. Epub 2018 Oct 11.

Department of Clinical Sciences and the Intracellular Pathogens Research Laboratory, Center for Comparative Medicine and Translational Research, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.

Background: Because of poor sensitivity and questionable specificity of immunofluorescent antibody assays (IFAs), serological diagnosis of Bartonella species infections in dogs remains challenging. Despite limitations, IFA testing is the historical "gold standard" for Bartonella serodiagnosis in animals and humans. Because most diagnostic laboratories test against only 1 or 2 Bartonella spp. Read More

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November 2018

Utility of Molecular Identification and Quantitation of Species with Species-Specific Real-Time PCR for Monitoring Treatment Response: A Case Series.

Open Microbiol J 2018 31;12:148-153. Epub 2018 May 31.

Infectious and Tropical Diseases Unit, Department of Medical and Surgical Sciences, "Magna Graecia" University of Catanzaro, Viale Europa, 88100, Catanzaro, Italy.

Background: Bartonella species are intracellular bacteria capable of producing several diseases in humans. The three most common and wellknown diseases are cat scratch disease (CSD), caused by B. henselae, trench fever, caused by and Carrion's Disease, caused by . Read More

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