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    33469 results match your criteria Trematode Infection

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    Effects of anthelmintic treatment and feed supplementation on parasite infections and morbidity parameters in Cambodian cattle.
    Vet Parasitol 2017 Feb 22;235:113-122. Epub 2017 Jan 22.
    Department of Biomedical Sciences, Institute of Tropical Medicine, Nationalestraat 155, B-2000, Antwerpen, Belgium; Department of Virology, Parasitology and Immunology, Salisburylaan 133, B-9820, Merelbeke, Belgium. Electronic address:
    Helminth infections are the cause of morbidity in Cambodian cattle but other factors such as nutritional deficiencies and concurrent diseases may enhance the effects of parasites. The present study aimed to investigate the impact of anthelmintic treatment, feed supplementation, or both on gastrointestinal strongyle (GIS) and trematode infections as well as on morbidity parameters in Cambodian village cattle. At the beginning of the dry season, cattle populations in six villages were randomly assigned to a group: (A) receiving anthelmintic treatment (ivermectin+clorsulon) at week 0; (P) feed pellet supplementation during week 0-13 or both (AP). Read More

    Arylmethylamino steroids as antiparasitic agents.
    Nat Commun 2017 Feb 17;8:14478. Epub 2017 Feb 17.
    Biochemistry and Molecular Biology, Interdisciplinary Research Centre, Justus Liebig University Giessen, Heinrich Buff Ring 26-32, 35392 Giessen, Germany.
    In search of antiparasitic agents, we here identify arylmethylamino steroids as potent compounds and characterize more than 60 derivatives. The lead compound 1o is fast acting and highly active against intraerythrocytic stages of chloroquine-sensitive and resistant Plasmodium falciparum parasites (IC50 1-5 nM) as well as against gametocytes. In P. Read More

    Species dependent impact of helminth-derived antigens on human macrophages infected with Mycobacterium tuberculosis: Direct effect on the innate anti-mycobacterial response.
    PLoS Negl Trop Dis 2017 Feb 13;11(2):e0005390. Epub 2017 Feb 13.
    Division of Medical Microbiology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden.
    Background: In countries with a high prevalence of tuberculosis there is high coincident of helminth infections that might worsen disease outcome. While Mycobacterium tuberculosis (Mtb) gives rise to a pro-inflammatory Th1 response, a Th2 response is typical of helminth infections. A strong Th2 response has been associated with decreased protection against tuberculosis. Read More

    [Ambiguous hepatic mass and fever after stay in Turkey].
    Internist (Berl) 2017 Feb 8. Epub 2017 Feb 8.
    Klinik für Innere Medizin, Gastroenterologie, Hämato-Onkologie, Pneumologie, Diabetologie und Infektiologie, Klinikum Ludwigsburg, Ludwigsburg, Deutschland.
    We report the case of a 76-year old female patient with a hepatic mass after staying in eastern Turkey. There were no indices for malignancy or an infection with Echinococcus or Entamoeba histolytica. Finally we diagnosed a Fascioliasis (liver fluke) and cured the patient successfully. Read More

    Mortality Trends for Neglected Tropical Diseases in the State of Sergipe, Brazil, 1980-2013.
    Infect Dis Poverty 2017 Feb 8;6(1):20. Epub 2017 Feb 8.
    University Hospital, Federal University of Sergipe, Rua Claudio Batista s/n, B. Santo Antonio, Aracaju, SE, 49060-108, Brazil.
    Background: Neglected Tropical Diseases are a set of communicable diseases that affect the population so low socioeconomic status, particularly 1.4 billion people who are living below the poverty level. This study has investigated the magnitude and mortality time trends for these diseases in the state of Sergipe, Northeast Region of Brazil. Read More

    The seasonal incidence of parasitic helminth infection among the walking catfish, Clarias batrachus of Tripura, India
    Ann Parasitol 2016 ;62(4):307-314
    Department of Zoology, North-Eastern Hill University, Mawlai, Shillong 793022, Meghalaya, India
    In the present study, a total of 868 walking catfish, Clarias batrachus, were collected during the period of April, 2012 to March, 2015, to evaluate the prevalence of helminth parasites from different parts of Tripura, Northeast India. Of these, 606 fish were found to be infected with one genus of trematode viz., Astiotrema, two genera of cestode viz. Read More

    Socio-ecological dynamics and challenges to the governance of Neglected Tropical Disease control.
    Infect Dis Poverty 2017 Feb 6;6(1):35. Epub 2017 Feb 6.
    Department of International Development, London School of Economics and Political Science, London, UK.
    The current global attempts to control the so-called "Neglected Tropical Diseases (NTDs)" have the potential to significantly reduce the morbidity suffered by some of the world's poorest communities. However, the governance of these control programmes is driven by a managerial rationality that assumes predictability of proposed interventions, and which thus primarily seeks to improve the cost-effectiveness of implementation by measuring performance in terms of pre-determined outputs. Here, we argue that this approach has reinforced the narrow normal-science model for controlling parasitic diseases, and in doing so fails to address the complex dynamics, uncertainty and socio-ecological context-specificity that invariably underlie parasite transmission. Read More

    Intestinal schistosomiasis in Uganda at high altitude (>1400 m): malacological and epidemiological surveys on Mount Elgon and in Fort Portal crater lakes reveal extra preventive chemotherapy needs.
    Infect Dis Poverty 2017 Feb 6;6(1):34. Epub 2017 Feb 6.
    Department of Parasitology, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, L3 5QA, UK.
    Background: Intestinal schistosomiasis is of public health importance in Uganda but communities living above 1400 m are not targeted for control as natural transmission is thought unlikely. To assess altitudinal boundaries and at-risk populations, conjoint malacological and epidemiological surveys were undertaken on Mount Elgon (1139 m-3937 m), in Fort Portal crater lakes and in the Rwenzori Mountains (1123 m-4050 m).

    Methods: Seventy freshwater habitats [Mount Elgon (37), Fort Portal crater lakes (23), Rwenzori Mountains (8) and Lake Albert (2)] were inspected for Biomphalaria species. Read More

    Brachylaima ezohelicis sp. nov. (Trematoda: Brachylaimidae) found from the land snail Ezohelix gainesi, with a note of an unidentified Brachylaima species in Hokkaido, Japan.
    Parasitol Int 2017 Jan 25;66(3):240-249. Epub 2017 Jan 25.
    School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
    In the Japanese Archipelago, Ezohelix gainesi, a member of bradybaenid land snails, is endemic mainly to the island of Hokkaido. During July to August of 2016, a survey to detect trematode infections from E. gainesi was carried out at a forest city park in Asahikawa, Hokkaido. Read More

    Population expansion and individual age affect endoparasite richness and diversity in a recolonising large carnivore population.
    Sci Rep 2017 Jan 27;7:41730. Epub 2017 Jan 27.
    Leibniz Institute for Zoo and Wildlife Research, Alfred-Kowalke-Straße 17, 10315 Berlin, Germany.
    The recent recolonisation of the Central European lowland (CEL) by the grey wolf (Canis lupus) provides an excellent opportunity to study the effect of founder events on endoparasite diversity. Which role do prey and predator populations play in the re-establishment of endoparasite life cycles? Which intrinsic and extrinsic factors control individual endoparasite diversity in an expanding host population? In 53 individually known CEL wolves sampled in Germany, we revealed a community of four cestode, eight nematode, one trematode and 12 potential Sarcocystis species through molecular genetic techniques. Infections with zoonotic Echinococcus multilocularis, Trichinella britovi and T. Read More

    De Novo Transcriptome Characterization of a Sterilizing Trematode Parasite (Microphallus sp.) from Two Species of New Zealand Snails.
    G3 (Bethesda) 2017 Jan 25. Epub 2017 Jan 25.
    University of Iowa.
    Snail-borne trematodes represent a large, diverse, and evolutionarily, ecologically, and medically important group of parasites, often imposing strong selection on their hosts and causing host morbidity and mortality. Even so, there are very few genomic and transcriptomic resources available for this important animal group. We help to fill this gap by providing transcriptome resources from trematode metacercariae infecting two congeneric snail species, Potamopyrgus antipodarum and P. Read More

    Antiparasitic activity, histopathology and physiology of Colossoma macropomum (tambaqui) exposed to the essential oil of Lippia sidoides (Verbenaceae).
    Vet Parasitol 2017 Jan 16;234:49-56. Epub 2016 Dec 16.
    Programa de Pós-Graduação em Biodiversidade Tropical (PPGBIO), Universidade Federal do Amapá (UNIFAP), Macapá, AP, Brazil; Embrapa Amapá, Macapá, AP, Brazil. Electronic address:
    In vivo and in vitro antiparasitic activity of the essential oil of Lippia sidoides and blood and histological alterations were assessed in Colossoma macropomum (tambaqui). Essential oil concentrations of 10, 20, 40, 80, 160 and 320mg/L were assayed in vitro against monogenoideans Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri from fish gills. Lippia sidoides essential oil concentrations of 320 and 160mg/L were 100% effective against monogenoideans in 10min and 1h of exposure, respectively. Read More

    Transcriptome profiling of gene expression during immunisation trial against Fasciola hepatica: identification of genes and pathways involved in conferring immunoprotection in a murine model.
    BMC Infect Dis 2017 Jan 23;17(1):94. Epub 2017 Jan 23.
    Parasite and Molecular Immunology Laboratory, Tropical Disease Research Centre, (IBSAL-CIETUS), University of Salamanca, Salamanca, Spain.
    Background: Fasciolosis remains a significant food-borne trematode disease causing high morbidity around the world and affecting grazing animals and humans. A deeper understanding concerning the molecular mechanisms by which Fasciola hepatica infection occurs, as well as the molecular basis involved in acquiring protection is extremely important when designing and selecting new vaccine candidates. The present study provides a first report of microarray-based technology for describing changes in the splenic gene expression profile for mice immunised with a highly effective, protection-inducing, multi-epitope, subunit-based, chemically-synthesised vaccine candidate against F. Read More

    Application of environmental DNA analysis for the detection of Opisthorchis viverrini DNA in water samples.
    Acta Trop 2017 Jan 17;169:1-7. Epub 2017 Jan 17.
    Graduate School of Human Development and Environment, Kobe University, 3-11, Tsurukabuto, Nada-ku, Kobe 657-8501 Japan. Electronic address:
    Opisthorchiasis, which can lead to cholangiocarcinoma in cases of chronic infection, is a major public health problem in Southeast Asian countries. The trematode, Opisthorchis viverrini, is the causative agent of the disease. Accurate and rapid monitoring of O. Read More

    Towards interruption of schistosomiasis transmission in sub-Saharan Africa: developing an appropriate environmental surveillance framework to guide and to support 'end game' interventions.
    Infect Dis Poverty 2017 Jan 14;6(1):10. Epub 2017 Jan 14.
    Centre for Schistosomiasis and Parasitology, Yaoundé, Cameroon.
    Schistosomiasis is a waterborne parasitic disease in sub-Saharan Africa, particularly common in rural populations living in impoverished conditions. With the scale-up of preventive chemotherapy, national campaigns will transition from morbidity- to transmission-focused interventions thus formal investigation of actual or expected declines in environmental transmission is needed as 'end game' scenarios arise. Surprisingly, there are no international or national guidelines to do so in sub-Saharan Africa. Read More

    J Zoo Wildl Med 2016 Dec;47(4):1044-1048
    The agouti ( Dasyprocta leporina ) is a New World wild rodent hunted for its meat in Trinidad and other Latin American countries. Studies on agouti under captive conditions have yielded some data on health-related aspects, but relatively very little is known about their wild counterparts. The environment of the agouti can influence the microflora and parasites harbored by the animals, which may contain zoonotic pathogens. Read More

    A mucin-like peptide from Fasciola hepatica instructs dendritic cells with parasite specific Th1-polarizing activity.
    Sci Rep 2017 Jan 12;7:40615. Epub 2017 Jan 12.
    Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.
    Fasciolosis is a trematode zoonosis of interest in public health and cattle production. We report here the immunostimulatory effect of a 66 mer mucin-like peptide from Fasciola hepatica (Fhmuc), which synergizes with lipopolysaccharide (LPS) to promote dendritic cell (DC) maturation, endowing these cells with Th1-polarizing capacity. Exposure of DCs to Fhmuc in presence of LPS induced enhanced secretion of pro-inflammatory cytokines and expression of co-stimulatory molecules by DCs, promoting their T cell stimulatory capacity and selectively augmenting IFN-γ secretion by allogeneic T cells. Read More

    Agreement among Four Prevalence Metrics for Urogenital Schistosomiasis in the Eastern Region of Ghana.
    Biomed Res Int 2016 18;2016:7627358. Epub 2016 Dec 18.
    Initiative for the Forecasting and Modeling of Infectious Diseases, Tufts University, Medford, MA 02155, USA; Department of Civil and Environmental Engineering, Tufts University School of Engineering, Medford, MA 02155, USA; Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA 02111, USA; Friedman School of Nutrition Science & Policy, Tufts University, Boston, MA 02111, USA.
    Few studies assess agreement among Schistosoma haematobium eggs, measured hematuria, and self-reported metrics. We assessed agreement among four metrics at a single time point and analyzed the stability of infection across two time points with a single metric. We used data from the Eastern Region of Ghana and constructed logistic regression models. Read More

    The distribution of echinostome parasites in ponds and implications for larval anuran survival.
    Parasitology 2017 Jan 11:1-11. Epub 2017 Jan 11.
    Department of Ecology and Evolutionary Biology,2019 Kraus Natural Sciences Building,830 North University Ave.,University of Michigan,Ann Arbor,MI 48109,USA.
    Parasites can influence host population dynamics, community composition and evolution. Prediction of these effects, however, requires an understanding of the influence of ecological context on parasite distributions and the consequences of infection for host fitness. We address these issues with an amphibian - trematode (Digenea: Echinostomatidae) host-parasite system. Read More

    Immediate and lag effects of pesticide exposure on parasite resistance in larval amphibians.
    Parasitology 2017 Jan 11:1-6. Epub 2017 Jan 11.
    Department of Forestry and Natural Resources,Purdue University,715 West State Street,West Lafayette,IN 47907,USA.
    Across host-parasite systems, there is evidence that pesticide exposure increases parasite loads and mortality following infection. However, whether these effects are driven by reductions in host resistance to infection or slower rates of parasite clearance is often unclear. Using controlled laboratory experiments, we examined the ability of larval northern leopard frogs (Lithobates pipiens) and American toads (Anaxyrus americanus) to resist and clear trematode (Echinoparyphium sp. Read More

    The ribosomal transcription units of Haplorchis pumilio and H. taichui and the use of 28S rDNA sequences for phylogenetic identification of common heterophyids in Vietnam.
    Parasit Vectors 2017 Jan 9;10(1):17. Epub 2017 Jan 9.
    College of Science and Engineering, James Cook University, Townsville, Australia.
    Background: Heterophyidiasis is now a major public health threat in many tropical countries. Species in the trematode family Heterophyidae infecting humans include Centrocestus formosanus, Haplorchis pumilio, H. taichui, H. Read More

    Clinostomum album n. sp. and Clinostomum marginatum (Rudolphi, 1819), parasites of the great egret Ardea alba L. from Mississippi, USA.
    Syst Parasitol 2017 Jan 6;94(1):35-49. Epub 2017 Jan 6.
    Thad Cochran National Warmwater Aquaculture Center, Aquatic Research & Diagnostic Laboratory, Delta Research and Extension Center, College of Veterinary Medicine, Mississippi State University, Stoneville, MS, 38776, USA.
    Members of the genus Clinostomum Leidy, 1856, colloquially known as yellow grubs, are cosmopolitan parasites of piscivorous birds, freshwater snails, fish and amphibians. In the southeastern United States, piscivorous birds present a continuous challenge for producers of farm-raised catfish. Ciconiiform birds are common hosts of Clinostomum spp. Read More

    Parasitic infections and maternal anaemia among expectant mothers in the Dangme East District of Ghana.
    BMC Res Notes 2017 Jan 3;10(1). Epub 2017 Jan 3.
    Department of Clinical Microbiology, School of Medicine and Health Sciences, University for Development Studies, Tamale, Ghana.
    Background: Parasitic infections are of public health concern globally, particular among at risk groups such as pregnant women in developing countries. The presence of these parasites during pregnancy potentiate adverse effects to both the mother and the unborn baby. This study sought to establish the prevalence of some parasitic agents among antenatal attendees in the Dangme East District of Ghana. Read More

    Occurrence and HAT-RAPD analysis of gastrointestinal helminths in domestic chickens (Gallus gallus domesticus) in Phayao province, northern Thailand.
    Saudi J Biol Sci 2017 Jan 9;24(1):30-35. Epub 2015 Sep 9.
    Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand; The Applied Technology for Biodiversity Research Unit, Science and Technology Research Institute, Chiang Mai University, Chiang Mai 50200, Thailand.
    The present study determined the prevalence and distribution of gastrointestinal helminths in domestic chickens (Gallus gallus domesticus) between November 2012 and August 2013. One hundred and twenty domestic chickens were purchased from villages in four districts of Phayao province; Mae Chai, Dok Khamtai, Chun and Chiang Kham. Morphological differences were used to identify the helminth species, and HAT-RAPD technique was used to differentiate among closely related species. Read More

    Characterization and vaccine potential of Fasciola gigantica saposin-like protein 1 (SAP-1).
    Vet Parasitol 2017 Jan 13;233:115-122. Epub 2016 Dec 13.
    Faculty of Allied Health Sciences, Burapha University, Long-Hard Bangsaen Road, Mueang District, Chonburi 20131, Thailand; Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand. Electronic address:
    The recombinant Fasciola gigantica Saposin-like protien-1 (rFgSAP-1) was cloned by polymerase chain reaction (PCR) from NEJ cDNA, expressed in Escherichia coli BL21 (DE3) and used for production of a polyclonal antibody in rabbits (anti-rFgSAP-1). By immunoblotting and immunohistochemistry, rabbit IgG anti-rFgSAP-1 reacted with rFgSAP-1 at a molecular weight 12kDa, but not with rFgSAP-2. The rFgSAP-1 reacted with antisera from mouse infected with F. Read More

    Bottom-up and trait-mediated effects of resource quality on amphibian parasitism.
    J Anim Ecol 2017 Mar 27;86(2):305-315. Epub 2016 Dec 27.
    Oakland University, 2200 N. Squirrel Rd., Rochester, MI, USA.
    Leaf litter subsidies are important resources for aquatic consumers like tadpoles and snails, causing bottom-up effects on wetland ecosystems. Recent studies have shown that variation in litter nutritional quality can be as important as litter quantity in driving these bottom-up effects. Resource subsidies likely also have indirect and trait-mediated effects on predation and parasitism, but these potential effects remain largely unexplored. Read More

    Elucidation of the first definitively identified life cycle for a marine turtle blood fluke (Trematoda: Spirorchiidae) enables informed control.
    Int J Parasitol 2017 Jan 18;47(1):61-67. Epub 2016 Dec 18.
    Fundación Oceanogràfic, Veterinary Services & Research Department, Avanqua Oceanogràfic-Ágora, C/ Eduardo Primo Yúfera 1B, 46013 Valencia, Spain.
    Blood flukes of the family Spirorchiidae are significant pathogens of both free-ranging and captive marine turtles. Despite a significant proportion of marine turtle mortality being attributable to spirorchiid infections, details of their life cycles remain almost entirely unknown. Here we report on the molecular elucidation of the complete life cycle of a marine spirorchiid, identified as Amphiorchis sp. Read More

    Evaluation of Lethal Giant Larvae as a Schistosomiasis Vaccine Candidate.
    Biomed Res Int 2016 9;2016:4680812. Epub 2016 Nov 9.
    Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture, Shanghai 200241, China.
    Schistosomiasis is a neglected tropical disease of humans, and it is considered to be the second most devastating parasitic disease after malaria. Eggs produced by normally developed female worms are important in the transmission of the parasite, and they responsible for the pathogenesis of schistosomiasis. The tumor suppressor gene lethal giant larvae (lgl) has an essential function in establishing apical-basal cell polarity, cell proliferation, differentiation, and tissue organization. Read More

    Decline in transmission of schistosomiasis mansoni in Oman.
    Infect Dis Poverty 2016 Dec 12;5(1):112. Epub 2016 Dec 12.
    Division of Communicable Diseases, World Health Organization Regional Office for the Eastern Mediterranean, Shara'a Abdul Razzak Al Sanhouri, PO Box 7608, Nasr City, 11371, Cairo, Egypt.
    Background: Intestinal schistosomiasis due to Schistosoma mansoni was first reported in Oman in 1979. We describe the trend in parasitological and serological prevalence of human infection with S. mansoni in the endemic area over the period 1982-2014, and the compliance of data generated by the national monitoring and evaluation system with schistosomiasis elimination criteria set by the Ministry of Health of Oman. Read More

    Fasciola hepatica demonstrates high levels of genetic diversity, a lack of population structure and high gene flow: possible implications for drug resistance.
    Int J Parasitol 2017 Jan 7;47(1):11-20. Epub 2016 Dec 7.
    Veterinary Parasitology, Institute of Infection and Global Health, University of Liverpool, Liverpool L3 5RF, UK.
    Fasciola hepatica, the liver fluke, is a trematode parasite of considerable economic importance to the livestock industry and is a re-emerging zoonosis that poses a risk to human health in F. hepatica-endemic areas worldwide. Drug resistance is a substantial threat to the current and future control of F. Read More

    A new global strategy for the elimination of schistosomiasis.
    Int J Infect Dis 2017 Jan 12;54:130-137. Epub 2016 Dec 12.
    Centre for Tropical and Emerging Global Health Diseases, University of Georgia, USA.
    Mass drug administration utilising a single oral dose of 40mg/kg of praziquantel (PZQ) has been endorsed and advocated by the World Health Organisation (WHO) for the global control and elimination of schistosomiasis. However, this strategy is failing primarily because the drugs are not getting to the people who need them the most. The current global coverage is 20%, the drug compliance rate is less than 50%, and the drug efficacy is approximately 50%. Read More

    Risk factors for Clonorchis sinensis infection transmission in humans in northern Vietnam: A descriptive and social network analysis study.
    Parasitol Int 2017 Apr 7;66(2):74-82. Epub 2016 Dec 7.
    WHO Collaborating Centre for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Tropical Disease Research Center, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address:
    Clonorchis sinensis is major fish-borne trematode, endemic in North Vietnam. Risk factors described so far include individual eating behaviors and environmental factors. Here, additional to conventional risk factors, we report on socially influenced liver fluke transmission in endemic communities. Read More

    Trematodes with a reproductive division of labour: heterophyids also have a soldier caste and early infections reveal how colonies become structured.
    Int J Parasitol 2017 Jan 30;47(1):41-50. Epub 2016 Nov 30.
    Department of Ecology, Evolution and Marine Biology, University of California, Santa Barbara, CA 93106, USA; Scripps Institution of Oceanography, Marine Biology Research Division, University of California, San Diego, La Jolla, CA 92093, USA.
    Recent findings have extended the documentation of complex sociality to the Platyhelminthes, describing the existence of a reproductive division of labour involving a soldier caste among the parthenitae of trematode parasites. However, all species examined to date occupy high positions in trematode interspecific dominance hierarchies and belong to two closely related families, the Echinostomatidae and the Philophthalmidae (Superfamily Echinostomatoidea). Further, the two species documented as lacking soldiers also belong to the Echinostomatidae. Read More

    Transmission of Calicophoron daubneyi and Fasciola hepatica in Galicia (Spain): Temporal follow-up in the intermediate and definitive hosts.
    Parasit Vectors 2016 Nov 29;9(1):610. Epub 2016 Nov 29.
    Laboratorio de Parasitología, Centro de Investigaciones Agrarias de Mabegondo, Instituto Galego de Calidade Alimentaria-Xunta de Galicia, Carretera AC-542 de Betanzos a Mesón do Vento, Km 7, 15318, Abegondo (A Coruña), Spain.
    Background: Paramphistomosis caused by Calicophoron daubneyi and fasciolosis caused by Fasciola hepatica are common parasitic diseases of livestock animals. Transmission of the diseases depends on the presence of intermediate hosts, i.e. Read More

    Comparison of molecular and conventional methods for the diagnosis of Fasciola hepatica infection in the field.
    Vet Parasitol 2016 Dec 6;232:8-11. Epub 2016 Nov 6.
    Department of Biomedical Sciences and Veterinary Public Health, Section for Parasitology, Swedish University of Agricultural Sciences (SLU), 75007 Uppsala, Sweden. Electronic address:
    The liver fluke, Fasciola hepatica, is one of the major parasite threats to livestock industries world-wide. In sheep and cattle, F. hepatica infection is commonly diagnosed using a range of methods. Read More

    Animal Fascioliasis: Perspectives from high altitudinal regions.
    Vet Parasitol 2016 Dec 9;232:21-31. Epub 2016 Nov 9.
    Department of Zoology, Northeastern Hill University, Shillong 793022, Meghalaya, India; Biotech Park, Kursi Road, Lucknow 226021, Uttar Pradesh, India. Electronic address:
    The parasitic flukes of the genus Fasciola (Platyhelminthes: Trematoda: Digenea) cause fascioliasis or liver-rot disease in ruminant livestock in tropical and sub-tropical regions of the world. Classically, two species of Fasciola- F. hepatica and F. Read More

    Re-infection with Fasciola gigantica 6-month post-treatment with triclabendazole in cattle from mobile pastoralist husbandry systems at Lake Chad.
    Vet Parasitol 2016 Oct 23;230:43-48. Epub 2016 Oct 23.
    Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland. Electronic address:
    At Lake Chad in central Africa, livestock fascioliasis caused by Fasciola gigantica represents a major veterinary health problem, particularly in cattle reared in mobile pastoralist husbandry systems. We assessed re-infection after a single dose of triclabendazole with fascioliasis in cattle in a mobile pastoralist setting towards the end of the dry season. Within the cattle herds of 14 groups of mobile pastoralists, 375 cattle were randomly selected. Read More

    Distribution of Foxp3(+) T cells in the liver and hepatic lymph nodes of goats and sheep experimentally infected with Fasciola hepatica.
    Vet Parasitol 2016 Oct 23;230:14-19. Epub 2016 Oct 23.
    Department of Animal Health (Parasitology), Faculty of Veterinary Medicine, University of Córdoba, Spain. Electronic address:
    Foxp3 regulatory T cells (Tregs) are now considered to play a key role in modulation of immune responses during parasitic helminth infections. Immunomodulation is a key factor in Fasciola hepatica infection; however, the distribution and role of Foxp3(+) Tregs cells have not been investigated in F. hepatica infected ruminants. Read More

    New locality record for Haplorchoides mehrai and possible interactions with Opisthorchis viverrini metacercariae in cyprinid fishes in Northeast Thailand.
    Parasitol Res 2017 Feb 23;116(2):601-608. Epub 2016 Nov 23.
    Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand.
    Metacercariae of Opisthorchis viverrini, a carcinogenic liver fluke, and Haplorchoides sp., a trematode maturing in catfish, are commonly found in cyprinid fish, the second intermediate hosts of both flukes. However, the specific identity of Haplorchoides sp. Read More

    Seasonal and Spatial Environmental Influence on Opisthorchis viverrini Intermediate Hosts, Abundance, and Distribution: Insights on Transmission Dynamics and Sustainable Control.
    PLoS Negl Trop Dis 2016 Nov 23;10(11):e0005121. Epub 2016 Nov 23.
    WHO Collaborating Centre for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Tropical Disease Research Laboratory, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
    Background: Opisthorchis viverrini (Ov) is a complex-life-cycle trematode affecting 10 million people in SEA (Southeast Asia). Human infection occurs when infected cyprinid fish are consumed raw or undercooked. Ov requires three hosts and presents two free-living parasitic stages. Read More

    Trematodes from the Northern Lapwing, Vanellus vanellus (Charadriidae), from Central Germany.
    Parasitol Res 2017 Feb 22;116(2):661-666. Epub 2016 Nov 22.
    Institute for Parasitology, Faculty for Veterinary Medicine, University of Leipzig, Leipzig, Germany.
    Seventy-five previously frozen Northern Lapwings, Vanellus vanellus (Linnaeus, 1758) were dissected and examined for trematodes. The available birds were euthanized after suffering severe injuries from a hail storm. Trematode specimens were found in the air sacs, body cavities and kidneys. Read More

    Bladder outlet obstruction; a rare complication of the neglected schistosome, Schistosoma haematobium: two case reports and public health challenges.
    BMC Res Notes 2016 Nov 22;9(1):493. Epub 2016 Nov 22.
    District Hospital Ndu, North West Region, Cameroon.
    Background: Schistosomiasis is a severe parasitic infestation with debilitating complications and is the third most devastating tropical disease in the world. It is one of the neglected tropical diseases (NTDs) with a high disease-burden. We present two rare cases of bladder outlet obstruction: one which led to a chronic kidney disease and ultimately death and a second which recovered after treatment with praziquantel. Read More

    Schistosomal-derived lysophosphatidylcholine triggers M2 polarization of macrophages through PPARγ dependent mechanisms.
    Biochim Biophys Acta 2017 Feb 15;1862(2):246-254. Epub 2016 Nov 15.
    Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, Brazil. Electronic address:
    Mansonic schistosomiasis is a disease caused by the trematode Schistosoma mansoni, endemic to tropical countries. S. mansoni infection induces the formation of granulomas and potent polarization of Th2-type immune response. Read More

    Consistency of trematode infection prevalence in host populations across large spatial and temporal scales.
    Ecology 2016 Jul;97(7):1643-1649
    Biology Department, East Carolina University, Greenville, North Carolina, 27858, USA.
    Parasites can impart heavy fitness costs on their hosts. Thus, understanding the spatial and temporal consistency in parasite pressure can elucidate the likeliness of parasites' role as agents of directional selection, as well as revealing variable environmental factors associated with infection risk. We examined spatiotemporal variation in digenetic trematode infection in 18 populations of an intertidal host snail (Littorina littorea) over a 300 km range at an 11-yr interval, more than double the generation time of the snail. Read More

    Repositioning of chlorambucil as a potential anti-schistosomal agent.
    Acta Trop 2017 Feb 9;166:58-66. Epub 2016 Nov 9.
    Department of Medical Parasitology, Faculty of Medicine, Alexandria University, Alexandria, Egypt. Electronic address:
    As parasites and cancer cells share many lifestyle and behavioral resemblances, repositioning of anti-cancerous agents as anti-parasitic is quite trendy, especially those sharing the same therapeutic targets. Therefore, the current study investigated the in vitro efficacy of ascending concentrations of chlorambucil (0.5-20μg/ml) against adult Schistosoma mansoni worms, over 72h. Read More

    Comparative Risk of Liver and Intestinal Fluke Infection from Either Wild-Caught or Cultured Fish in Vietnam.
    Vector Borne Zoonotic Dis 2016 Dec 9;16(12):790-796. Epub 2016 Nov 9.
    3 Department of Preventive Medicine and Biometrics, School of Medicine, Uniformed Services University of the Health Sciences , Bethesda, Maryland.
    A survey for fish-borne zoonotic trematode (FZT) metacercariae in fish from the Northern Mountain Region of Vietnam was conducted from May to August 2014. The major objective was to evaluate the impact of water body types on the prevalence of FZT. A total of 846 fish (31 species) were collected from three water body types, including aquaculture ponds, rivers, and reservoirs. Read More

    Development of a PCR Assay for Diagnosing Trematode (Opisthorchis and Haplorchis) Infections in Human Stools.
    Am J Trop Med Hyg 2017 Jan 7;96(1):221-228. Epub 2016 Nov 7.
    Department of Public Health, Kansai Medical University, Osaka, Japan.
    We developed a combined conventional polymerase chain reaction (PCR) and real-time PCR (qPCR)-based assay for detecting and discriminating between Opisthorchis viverrini and Haplorchis taichui parasite infections. The first PCR amplifies the mitochondrial cytochrome c oxidase subunit I (COI) genes of parasites, and differential diagnosis is achieved by performing qPCR with specific primers and SYBR Green I. The detection limit of the assay was found to be 2. Read More

    Recombinase Polymerase Amplification Compared to Real-Time Polymerase Chain Reaction Test for the Detection of Fasciola hepatica in Human Stool.
    Am J Trop Med Hyg 2017 Feb 7;96(2):341-346. Epub 2016 Nov 7.
    Infectious Diseases Division, Department of Internal Medicine, University of Texas Medical Branch, Galveston, Texas.
    Fasciola hepatica is the most widely distributed trematode infection in the world. Control efforts may be hindered by the lack of diagnostic capacity especially in remote endemic areas. Polymerase chain reaction (PCR)-based methods offer high sensitivity and specificity but require expensive technology. Read More

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