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    The Pattern of Uveitis in Sri Lanka.
    Ocul Immunol Inflamm 2017 May 24:1-6. Epub 2017 May 24.
    a Singapore National Eye Centre , Singapore Eye Research Institute , Singapore.
    Purpose: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka.

    Methods: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed.

    Results: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). Read More

    A review of bovine fasciolosis and other trematode infections in Nigeria.
    J Helminthol 2017 May 22:1-14. Epub 2017 May 22.
    University of Bristol,School of Veterinary Science,Langford, Bristol,BS40 5DU,UK.
    Trematode infections cause serious economic losses to livestock worldwide. Global production losses due to fasciolosis alone exceed US$3 billion annually. Many trematode infections are also zoonotic and thus a public health concern. Read More

    Host density increases parasite recruitment but decreases host risk in a snail-trematode system.
    Ecology 2017 May 18. Epub 2017 May 18.
    U.S. Geological Survey, Western Ecological Research Center, c/o Marine Science Institute University of California Santa Barbara, Santa Barbara, CA, 93106, USA.
    Most species aggregate in local patches. High host density in patches increases contact rate between hosts and parasites, increasing parasite transmission success. At the same time, for environmentally-transmitted parasites, high host density can decrease infection risk to individual hosts, because infective stages are divided among all hosts in a patch, leading to safety in numbers. Read More

    Infection, specificity and host manipulation of Australapatemon sp. (Trematoda, Strigeidae) in two sympatric species of leeches (Hirudinea).
    Parasitology 2017 May 15:1-10. Epub 2017 May 15.
    Department of Biological and Environmental Science,University of Jyvaskyla,PO Box 35, 40014 Jyvaskyla,Finland.
    Factors that drive parasite specificity and differences in infection dynamics among alternative host species are important for ecology and evolution of host-parasite interactions, but still often poorly known in natural systems. Here, we investigated spatiotemporal dynamics of infection, host susceptibility and parasite-induced changes in host phenotype in a rarely explored host-parasite system, the Australapatemon sp. trematode infecting two sympatric species of freshwater leeches, Erpobdella octoculata and Helobdella stagnalis. Read More

    Medicinal chemistry of antischistosomal drugs: Praziquantel and oxamniquine.
    Bioorg Med Chem 2017 Apr 27. Epub 2017 Apr 27.
    Laboratório de Química e Inovação Terapêutica (LQIT), Departamento de Antibióticos, Centro de Ciências Biológicas, Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego s/n, Cidade Universitária, 50670-901 Recife, PE, Brazil. Electronic address:
    Neglected tropical diseases (NTDs) are a group of diseases that, besides prevailing in poverty conditions, contribute to the maintenance of social inequality, being a strong barrier to a country development. Schistosomiasis, a NTD, is a tropical and subtropical disease caused by the trematode Schistosoma mansoni (Africa, Middle East, Caribbean, Brazil, Venezuela, Suriname), japonicum (China, Indonesia, the Philippines), mekongi (several districts of Cambodia and the Lao People's Democratic Republic), intercalatum and guianensis (areas of tropical rainforests in Central Africa) and hematobium (Middle East Africa, Corsica, France) whose adult forms inhabit the mesenteric vessels of the host, while the intermediate forms are found in the aquatic gastropod snails of the genus Biomphalaria. Currently, praziquantel (PZQ) is the first line drug chosen for the treatment of schistosomiasis according to the World Health Organization (WHO) Model List of Essential Medicines, 2015. Read More

    Network Analysis of the Systemic Response to Fasciola hepatica Infection in Sheep Reveals Changes in Fibrosis, Apoptosis, Toll-Like Receptors 3/4, and B Cell Function.
    Front Immunol 2017 25;8:485. Epub 2017 Apr 25.
    UCD School of Veterinary Medicine, University College Dublin, Dublin, Ireland.
    The Trematode Fasciola hepatica is an important cause of disease in livestock and in man. Modulation of immunity is a critical strategy used by this parasite to facilitate its long-term survival in the host. Understanding the underlying mechanisms at a system level is important for the development of novel control strategies, such as vaccination, as well as for increasing general understanding of helminth-mediated immunoregulation and its consequences. Read More

    Th9 Cells and Parasitic Inflammation: Use of Nippostrongylus and Schistosoma Models.
    Methods Mol Biol 2017 ;1585:223-245
    Departamento de Biología Celular y del Desarrollo, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Coyoacán, 04510, Mexico City, Mexico.
    Th9 cells are a new subpopulation of CD4+ T helper cells, characterized by the expression of IL-9 that have been involved in type 2 immune responses, antitumor responses and autoimmune diseases. Here, we describe two different parasitic models frequently maintained in the laboratory where Th9 cells or IL-9 (the cytokine produced by Th9 cells) has been shown to play critical roles in pathogen clearance and immune response activation: the nematode Nippostrongylus brasiliensis and the trematode Schistosoma mansoni. Read More

    Behavioural modification of personality traits: testing the effect of a trematode on nymphs of the red damselfly Xanthocnemis zealandica.
    Parasitol Res 2017 Jun 4;116(6):1773-1779. Epub 2017 May 4.
    Department of Zoology, University of Otago, PO Box 56, Dunedin, 9054, New Zealand.
    Research on animal personality is increasingly demonstrating that individuals in a population are characterised by distinct sets of behavioural traits that show consistency over time and across different situations. Parasites are known to alter the behaviour of their hosts, although their role in shaping host personality remains little studied. Here, we test the effect of trematode infection on two traits of their host's personality, activity and boldness, in nymphs of the red damselfly Xanthocnemis zealandica. Read More

    Genomic evidence for population-specific responses to co-evolving parasites in a New Zealand freshwater snail.
    Mol Ecol 2017 Apr 21. Epub 2017 Apr 21.
    Department of Biology, University of Iowa, Iowa City, IA, USA.
    Reciprocal co-evolving interactions between hosts and parasites are a primary source of strong selection that can promote rapid and often population- or genotype-specific evolutionary change. These host-parasite interactions are also a major source of disease. Despite their importance, very little is known about the genomic basis of co-evolving host-parasite interactions in natural populations, especially in animals. Read More

    Trematode Aspidogastrea found in the freshwater mussels in the Yangtze River basin.
    Nutr Hosp 2017 Mar 30;34(2):460-462. Epub 2017 Mar 30.
    Department of Medical Parasitology. Wannan Medical College. Wuhu, Anhu. China.
    Objective: To investigate the prevalence of trematode Aspidogastrea in the freshwater mussels in the Yangtze River basin within Anhui province, China.

    Methods: We initially harvested the freshwater mussels living in the Yangtze River running through Anhui area, and labeled them with corresponding number. Then the samples were dissected for isolating the flukes, which were identified by conventional staining. Read More

    Assessing environmental factors associated with regional schistosomiasis prevalence in Anhui Province, Peoples' Republic of China using a geographical detector method.
    Infect Dis Poverty 2017 Apr 17;6(1):87. Epub 2017 Apr 17.
    Department of Epidemiology, School of Public Health, Fudan University, Shanghai, 200032, China.
    Background: Schistosomiasis is a water-borne disease caused by trematode worms belonging to genus Schistosoma, which is prevalent most of the developing world. Transmission of the disease is usually associated with multiple biological characteristics and social factors but also factors can play a role. Few studies have assessed the exact and interactive influence of each factor promoting schistosomiasis transmission. Read More

    The immunoregulatory effects of co-infection with Fasciola hepatica: From bovine tuberculosis to Johne's disease.
    Vet J 2017 Apr 2;222:9-16. Epub 2017 Mar 2.
    UCD School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland.
    Fasciola hepatica (liver fluke) is a parasite prevalent in much of the world that causes the economically-important disease of fasciolosis in livestock. The threat that this disease poses extends beyond its direct effects due to the parasite's immunomodulatory effects. Research at this laboratory is focusing on whether this immunoregulation can, in animals infected with liver fluke, exert a bystander effect on concurrent infections in the host. Read More

    Mathematical algorithm for the automatic recognition of intestinal parasites.
    PLoS One 2017 14;12(4):e0175646. Epub 2017 Apr 14.
    Unidad de Bioinformática, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Perú.
    Parasitic infections are generally diagnosed by professionals trained to recognize the morphological characteristics of the eggs in microscopic images of fecal smears. However, this laboratory diagnosis requires medical specialists which are lacking in many of the areas where these infections are most prevalent. In response to this public health issue, we developed a software based on pattern recognition analysis from microscopi digital images of fecal smears, capable of automatically recognizing and diagnosing common human intestinal parasites. Read More

    Nested-PCR assay for detection of Schistosoma japonicum infection in domestic animals.
    Infect Dis Poverty 2017 Apr 13;6(1):86. Epub 2017 Apr 13.
    Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Key Laboratory of Animal Parasitology, Ministry of Agriculture, Shanghai, 200241, People's Republic of China.
    Background: Schistosomiasis japonica is a common zoonosis. Domestic animals are the primary source of infection and play an important role in disease transmission. The prevalence and infectivity of this disease in domestic animals in China have significantly decreased and, for this reason, diagnostics with a higher sensitivity have become increasingly necessary. Read More

    A novel colloidal gold immunochromatography assay strip for the diagnosis of schistosomiasis japonica in domestic animals.
    Infect Dis Poverty 2017 Apr 7;6(1):84. Epub 2017 Apr 7.
    Key Laboratory of Animal Parasitology, Ministry of Agriculture of China, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No.518, Ziyue Road, Minhang District, Shanghai, 200241, China.
    Background: Schistosomiasis remains a major public health concern in China and an epidemiological survey has revealed that schistosome-infected bovines and goats are the main transmission sources for the disease. Therefore, development of a sensitive technique for the diagnosis of schistosomiasis in domestic animals is necessary.

    Method: A novel colloidal gold immunochromatography assay (GICA) strip was developed for detecting Schistosoma japonicum in domestic animals. Read More

    Putting the treatment of paediatric schistosomiasis into context.
    Infect Dis Poverty 2017 Apr 7;6(1):85. Epub 2017 Apr 7.
    Institute of Immunology & Infection Research, University of Edinburgh, Ashworth Laboratories, King's Buildings, Charlotte Auerbach Road, Edinburgh, EH9 3FL, UK.
    Despite increased international efforts to control schistosomiasis using preventive chemotherapy, several challenges still exist in reaching the target populations. Until recently, preschool-aged children had been excluded from the recommended target population for mass drug administration, i.e. Read More

    Interruption of schistosomiasis transmission in mountainous and hilly regions with an integrated strategy: a longitudinal case study in Sichuan, China.
    Infect Dis Poverty 2017 Apr 7;6(1):79. Epub 2017 Apr 7.
    Department of Health Education, West China School of Public Health, Sichuan University, No. 16 Renmin South Road, Chengdu, 610041, Sichuan Province, China.
    Background: Schistosomiasis remains a major public health concern in China. Since 2004, an integrated strategy was developed to control the transmission of Schistosoma japonicum in China. However, the long-term effectiveness of this integrated strategy for the interruption of schistosomiasis transmission remains unknown in the mountainous and hilly regions of China until now. Read More

    Efficacy of praziquantel on Schistosoma haematobium and re-infection rates among school-going children in the Ndumo area of uMkhanyakude district, KwaZulu-Natal, South Africa.
    Infect Dis Poverty 2017 Apr 7;6(1):83. Epub 2017 Apr 7.
    School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa.
    Background: Despite its low cure rates and possible resistance, praziquantel (PZQ) is the only drug available for schistosomiasis treatment. Hence, monitoring its efficacy is crucial. This study assessed the efficacy of PZQ, determined re-infection and incidence rates of Schistosoma haematobium infection among school-going children in the Ndumo area, KwaZulu-Natal. Read More

    Selecting accurate post-elimination monitoring tools to prevent reemergence of urogenital schistosomiasis in Morocco: a pilot study.
    Infect Dis Poverty 2017 Apr 6;6(1):75. Epub 2017 Apr 6.
    National Reference Laboratory for Schistosomiasis and Malacology, National Institute of Hygiene, Agdal, Rabat, Morocco.
    Background: After alleged stop of transmission of schistosomiasis and further down the line in post elimination settings, sensitive tools are required to monitor infection status to prevent potential re-emergence. In Rahala, where transmission cycle of Schistosoma haematobium is interrupted since 2004 but where 30% of snails are still infected by S. bovis, potential human S. Read More

    Fish sharing as a risk factor for Opisthorchis viverrini infection: evidence from two villages in north-eastern Thailand.
    Infect Dis Poverty 2017 Apr 4;6(1):66. Epub 2017 Apr 4.
    WHO Collaborating Centre for Research and Control of Opisthorchiasis (Southeast Asian Liver Fluke Disease), Tropical Disease Research Laboratory, Department of Pathology, Faculty of Medicine, Khon Kaen University, 123 Mittraparb Road, Khon Kaen, 40002, Thailand.
    Background: Foodborne trematodiasis (FBT) is a significant global health problem, with the liver flukes Opisthorchis viverrini, O. felineus, and Clonorchis sinensis contributing to half of the global burden of FBT. North-eastern Thailand where O. Read More

    Rapid mapping of urinary schistosomiasis: An appraisal of the diagnostic efficacy of some questionnaire-based indices among high school students in Katsina State, northwestern Nigeria.
    PLoS Negl Trop Dis 2017 Apr 3;11(4):e0005518. Epub 2017 Apr 3.
    Department of Biological Sciences, Faculty of Science, Federal University Dutsinma, Dutsin-Ma, Katsina State, Nigeria.
    Background: In sub-Saharan Africa, over 200 million individuals are estimated to be infected with urinary and intestinal schistosomiasis. In a bid to lay a foundation for effective future control programme, this study was carried out with the aim of assessing the diagnostic efficacy of some questionnaire-based rapid assessment indices of urinary schistosomiasis.

    Methodology: A total number of 1,363 subjects were enrolled for the study. Read More

    Pulmonary shunts in severe hepatosplenic schistosomiasis: Diagnosis by contrast echocardiography and their relationship with abdominal ultrasound findings.
    PLoS Negl Trop Dis 2017 Apr 3;11(4):e0005417. Epub 2017 Apr 3.
    Department of Clinical Medicine, Universidade Federal de Pernambuco, Recife, Brazil.
    Background: Schistosomiasis is endemic to several parts of the world. Among the species that affect humans, Schistosoma mansoni is one of the most common causes of illness. In regions where schistosomiasis mansoni is endemic, reinfection is responsible for the emergence of hepatosplenic schistosomiasis (HSS) with portal hypertension in about 10% of infected individuals. Read More

    TREATMENT OF PULMONICOLA COCHLEOTREMA INFECTION WITH IVERMECTIN-PRAZIQUANTEL COMBINATION IN AN ANTILLEAN MANATEE (TRICHECHUS MANATUS MANATUS).
    J Zoo Wildl Med 2017 Mar;48(1):217-219
    The aim of this study was to report the use of an oral combination of ivermectin plus praziquantel in the treatment of a Pulmonicola cochleotrema in an Antillean manatee ( Trichechus manatus manatus). A female manatee was found exhibiting respiratory changes and the presence of parasites in the nares. Based on clinical manifestations presented by the manatee, a symptomatic therapeutic protocol was employed, which included an anthelmintic treatment using a combination of ivermectin plus praziquantel. Read More

    Barbatic Acid Offers a New Possibility for Control of Biomphalaria Glabrata and Schistosomiasis.
    Molecules 2017 Mar 31;22(4). Epub 2017 Mar 31.
    Departamento de Bioquímica e Fisiologia, Universidade Federal de Pernambuco, Recife, PE 50670-901, Brazil.
    This study evaluated the biological activity of an ether extract and barbatic acid (BAR) from Cladia aggregata on embryos and adult mollusks of Biomphalaria glabrata, cercariae of Schistosoma mansoni and the microcrustacean Artemia salina. The ether extract and BAR were obtained by successive extractions with diethyl ether. The obtained extracts were analyzed using thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), proton nuclear magnetic resonance (¹H-NMR) and infrared (IR) spectroscopy. Read More

    Fasciola hepatica Immune Regulates CD11c(+) Cells by Interacting with the Macrophage Gal/GalNAc Lectin.
    Front Immunol 2017 15;8:264. Epub 2017 Mar 15.
    Grupo de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República , Montevideo , Uruguay.
    Fasciolosis, caused by Fasciola hepatica and Fasciola gigantica, is a trematode zoonosis of interest in public health and livestock production. Like other helminths, F. hepatica modulates the host immune response by inducing potent polarized Th2 and regulatory T cell immune responses and by downregulating the production of Th1 cytokines. Read More

    A new method for estimating the prevalence of clonorchiasis in Korea: A proposal to replace arbitrary riverside sampling.
    Medicine (Baltimore) 2017 Mar;96(13):e6536
    aDepartment of Preventive Medicine, Okcheon-gun Public Health Center, Okcheon-gun, Chungcheongbuk-do bPublic Health Medical Service, Boramae Medical Center, Seoul National University College of Medicine, Seoul cInstitute of Health Policy and Management, Medical Research Center, Seoul National University, Seoul dDivision of Malaria and Parasitic Diseases, National Institute of Health, Centers for Disease Control and Prevention, Cheongju, Chungcheongbuk-do eTaean-gun Hospitalized Public Health Center, Taeangun, Chungcheongnam-do fSeoul National University College of Medicine, Seoul gDepartment of Nursing Science, Shinsung University, Dangjin-si, Chungcheongnam-do, South Korea.
    South Korea presently uses an arbitrary sampling method to monitor the prevalence of Clonorchis sinensis infection in the endemic areas of the country. However, the present method is not standardized and focuses primarily on individuals who reside nearest to the mainstream river. We propose a new sampling method that combines cluster sampling with proportionate quota sampling to ensure that the entire endemic area is accurately represented. Read More

    Controlling schistosomiasis with praziquantel: How much longer without a viable alternative?
    Infect Dis Poverty 2017 Mar 28;6(1):74. Epub 2017 Mar 28.
    Swiss Tropical and Public Health Institute, P.O. Box, CH-4002, Basel, Switzerland.
    The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquantel. There is a pressing need for new drugs against this disease whose control entirely depends on this single drug that has been widely used over the past 40 years. We argue that a broader anthelminthic approach supplementing praziquantel with new antischistosomals targeting different parasite development stages would not only increase efficacy but also reduce the risk for drug resistance. Read More

    SEASONAL AND ANNUAL VARIATION IN TREMATODE INFECTION OF STREAM SNAILS, ELIMIA PROXIMA, IN THE SOUTHERN APPALACHIAN MOUNTAINS OF VIRGINIA.
    J Parasitol 2017 Mar 3. Epub 2017 Mar 3.
    * Virginia Polytechnic Institute and State University Graduate student Department of Biological Sciences Virginia Polytechnic Institute and State University.
    Understanding temporal variation of host-pathogen dynamics can be important for predicting disease risks and anticipating how disease systems may change in response to natural or human disturbances. Seasonal changes in weather, especially those associated with changes in temperature or precipitation, are often a key component of temporal changes in infection risk and can have important impacts on disease systems. However, these patterns can be difficult to track due to interannual variation and the need for longer-term, multi-year surveillance efforts. Read More

    The role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer.
    Tumour Biol 2017 Mar;39(3):1010428317692247
    2 Center for the Study of Animal Science, ICETA, University of Porto, Porto, Portugal.
    Urogenital schistosomiasis is a neglected tropical disease that can lead to bladder cancer. How urogenital schistosomiasis induces carcinogenesis remains unclear, although there is evidence that the human blood fluke Schistosoma haematobium, the infectious agent of urogenital schistosomiasis, releases estradiol-like metabolites. These kind of compounds have been implicated in other cancers. Read More

    An integrated environmental improvement of marshlands: impact on control and elimination of schistosomiasis in marshland regions along the Yangtze River, China.
    Infect Dis Poverty 2017 Mar 22;6(1):72. Epub 2017 Mar 22.
    Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, No. 117 Yangxiang, Meiyuan, Wuxi City, Jiangsu Province, 214064, China.
    Background: Schistosomiasis is a global snail-transmitted infectious disease of poverty. Transmission control had been achieved in China in 2015 after the control efforts for over 60 years. Currently, the remaining core regions endemic for Schistosoma japonicum are mainly located in the marshland and lake regions along the Yangtze River basin. Read More

    Building a global schistosomiasis alliance: an opportunity to join forces to fight inequality and rural poverty.
    Infect Dis Poverty 2017 Mar 23;6(1):65. Epub 2017 Mar 23.
    National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention, Shanghai, China.
    Schistosomiasis, one of the 17 neglected tropical diseases listed by the World Health Organization, presents a substantial public health and economic burden. Of the 261 million people requiring preventive chemotherapy for schistosomiasis in 2013, 92% of them lived in sub-Saharan Africa and only 12.7% received preventive chemotherapy. Read More

    Cellular immunodeficiency related to chronic dermatophytosis in a patient with Schistosoma mansoni infection: can schistosomiasis induce immunodeficiency?
    Rev Soc Bras Med Trop 2017 Jan-Feb;50(1):141-144
    Ambulatório de Manifestações Cutâneas das Imunodeficiências Primárias, Departamento de Dermatologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil.
    Here, we describe a case of hepatosplenic schistosomiasis that progressed to widespread persistent dermatophytosis. Significant T and B lymphocytopenia was confirmed. T-cell deficit is associated with increased susceptibility to fungal infections of skin and mucous membranes. Read More

    Schistosomiasis is more prevalent than previously thought: what does it mean for public health goals, policies, strategies, guidelines and intervention programs?
    Infect Dis Poverty 2017 Mar 22;6(1):63. Epub 2017 Mar 22.
    Schistosomiasis Consortium for Operational Research and Evaluation (SCORE), Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, 500 DW Brooks Drive, Room 330B Coverdell Center, Athens, Georgia, 30602, USA.
    Mapping and diagnosis of infections by the three major schistosome species (Schistosoma haematobium, S. mansoni and S. japonicum) has been done with assays that are known to be specific but increasingly insensitive as prevalence declines or in areas with already low prevalence of infection. Read More

    Carcinosarcoma of the bladder following local schistosomiasis infection.
    BMJ Case Rep 2017 Mar 21;2017. Epub 2017 Mar 21.
    Department of Urology, University of Sao Paulo Medical School, Sao Paulo, SP, Brazil.
    A young patient from central Africa presented acute renal insufficiency due to extrinsic compression of the distal ureters by a pelvic mass. After initial medical management, a biopsy revealed poorly differentiated bladder cancer and Schistosoma haematobium eggs embedded in the bladder wall. The initial workup showed evidence of locoregional disease. Read More

    Prey species of franciscana Pontoporia blainvillei as paratenic hosts of helminths.
    Dis Aquat Organ 2017 Mar;123(3):251-256
    Graduate Program in Biotechnology, Technology Development Center, Federal University of Pelotas, Pelotas 96001-970, RS, Brazil.
    The distribution of franciscana Pontoporia blainvillei Gervais & d'Orbigny, 1884, is restricted to the estuarine and coastal waters of the southwestern Atlantic. The diet of this dolphin is composed of fishes, squids, and shrimps, many of which harbor helminths that may infect franciscana. Larval forms of the trematode Synthesium pontoporiae and the acanthocephalan Bolbosoma turbinella have been recorded in franciscana; however, they have not yet been identified in any of the prey species of this cetacean. Read More

    The benefits of coinfection: trematodes alter disease outcomes associated with virus infection.
    J Anim Ecol 2017 Mar 20. Epub 2017 Mar 20.
    Department of Forestry and Natural Resources, Purdue University, West Lafayette, IN, 47907, USA.
    Coinfections are increasingly recognized as important drivers of disease dynamics. Consequently, greater emphasis has been placed on integrating principles from community ecology with disease ecology to understand within-host interactions among parasites. Using larval amphibians and two amphibian parasites (ranaviruses and the trematode Echinoparyphium sp. Read More

    Local site differences in survival and parasitism of periwinkles (Littorina sitkana Philippi, 1846).
    Ecol Evol 2017 Feb 18;7(4):1021-1029. Epub 2017 Jan 18.
    Bamfield Marine Sciences CentreBamfieldBCCanada; Department of BiologyUniversity of VictoriaVictoriaBCCanada.
    The periwinkle, Littorina sitkana, is found throughout the intertidal zone, often in isolated subpopulations. The majority of trematode parasites use snails as intermediate hosts, and decreased survivorship is often observed in snails infected with trematodes. Sampling L. Read More

    Approaches being used in the national schistosomiasis elimination programme in China: a review.
    Infect Dis Poverty 2017 Mar 15;6(1):55. Epub 2017 Mar 15.
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai, 200025, China.
    Schistosomiasis japonica, caused by the human blood fluke Schistosoma japonicum, remains a major public health problem in China, although great success has been achieved. The control efforts during the past half-decade, notably the wide implementation of the new integrated strategy with emphasis on control of the source of S. japonicum infection across the country since 2004, has greatly reduced S. Read More

    Crohn's disease and schistosomiasis: a rare association.
    Pan Afr Med J 2016 31;25:124. Epub 2016 Oct 31.
    University of Tunis El Manar, Faculty of Medicine of Tunis, 1007, Tunisia.
    Schistosomiasis is a chronic enteropathogenic disease caused by blood flukes of the genus Schistosoma. Coexistence of schistosomiasis with Crohn's disease is very rare. To the best of our knowledge, this association has been described in literature only once. Read More

    A multidisciplinary, integrated approach for the elimination of schistosomiasis: a longitudinal study in a historically hyper-endemic region in the lower reaches of the Yangtze River, China from 2005 to 2014.
    Infect Dis Poverty 2017 Mar 14;6(1):56. Epub 2017 Mar 14.
    Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, No. 117 Yangxiang, Meiyuan, Wuxi City, Jiangsu Province, 214064, China.
    Background: Although great success has been achieved, schistosomiasis remains a major public health concern in China, and the remaining core endemic regions are concentrated along the middle and lower reaches of the Yangtze River. In this longitudinal study, we evaluated the effectiveness of a multidisciplinary, integrated approach for schistosomiasis elimination in a historically hyper-endemic region in the lower reaches of the Yangtze River, China over the 10-year period from 2005 through 2014.

    Methods: A three-step roadmap for schistosomiasis elimination was designed in the study site, and multidisciplinary, integrated interventions were implemented by the health, agriculture, water resources development, land and resources, and forestry sectors from 2005 to 2014, including chemotherapy for infected individuals, health education, management of the source of Schistosoma japonicum infection, and intermediate host snail control. Read More

    Fasciola hepatica: Infection Status of Freshwater Snails Collected from Gangwon-do (Province), Korea.
    Korean J Parasitol 2017 Feb 28;55(1):95-98. Epub 2017 Feb 28.
    Department of Infection Biology, Chungnam National University College of Medicine, Daejeon 35015, Korea.
    Fasciola hepatica is a trematode that causes zoonosis, mainly in cattle and sheep, and occasionally in humans. Few recent studies have determined the infection status of this fluke in Korea. In August 2015, we collected 402 samples of freshwater snails at Hoenggye-ri (upper stream) and Suha-ri (lower stream) of Song-cheon (stream) in Daegwalnyeong-myeon, Pyeongchang-gun in Gangwon-do (Province) near many large cattle or sheep farms. Read More

    Seroprevalence and Risk Factors of Fascioliasis in Yaks, Bos grunniens, from Three Counties of Gansu Province, China.
    Korean J Parasitol 2017 Feb 28;55(1):89-93. Epub 2017 Feb 28.
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu 730046, China.
    The aim of this study was to determine the seroprevalence and risk factors of fascioliasis in yaks, Bos grunniens, from 3 counties of Gansu Province in China. A total of 1,584 serum samples, including 974 samples from white yaks from Tianzhu, 464 from black yaks from Maqu, and 146 from black yaks from Luqu County, were collected and analyzed using ELISA to detect IgG antibodies against Fasciola hepatica. The overall F. Read More

    Human Cases of Fascioliasis in Fujian Province, China.
    Korean J Parasitol 2017 Feb 28;55(1):55-60. Epub 2017 Feb 28.
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, WHO Collaborating Center for Tropical Diseases, Key Laboratory of Parasite and Vector Biology, National Health and Family Planning Commission, Shanghai 200025, China.
    Fascioliasis is a foodborne zoonotic parasitic disease. We report 4 cases occurring in the same family, in whom diagnosis of acute fascioliasis was established after series of tests. One case was hospitalized with fever, eosinophilia, and hepatic lesions. Read More

    Morphological Characteristics and Phylogenetic Trends of Trematode Cercariae in Freshwater Snails from Nakhon Nayok Province, Thailand.
    Korean J Parasitol 2017 Feb 28;55(1):47-54. Epub 2017 Feb 28.
    Parasitology Research Laboratory, Department of Biology, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand.
    The prevalence of cercarial infection in freshwater snails and their evolutionary trends were studied in Nakhon Nayok province, Thailand. A total of 2,869 individual snails were examined for parasitic infections. The results showed that 12 snail species were found to host larval stages of trematodes with an overall prevalence of 4. Read More

    Platynosomum fastosum (Trematoda: Dicrocoeliidae) from Cats in Vietnam: Morphological Redescription and Molecular Phylogenetics.
    Korean J Parasitol 2017 Feb 28;55(1):39-45. Epub 2017 Feb 28.
    Department of Molecular Systematics and Conservation Genetics, Institute of Ecology and Biological Resources (IEBR), Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
    The present study was performed to reveal the morphological characteristics and molecular phylogenetic position of Platynosomum fastosum Kossack, 1910. A total 167 specimens of P. fastosum were collected in 8 (4. Read More

    Molecular Phylogenetics of Centrocestus formosanus (Digenea: Heterophyidae) Originated from Freshwater Fish from Chiang Mai Province, Thailand.
    Korean J Parasitol 2017 Feb 28;55(1):31-37. Epub 2017 Feb 28.
    Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
    This study aimed to investigate the morphology and reconstruct the phylogenetic relationships of Centrocestus formosanus originating from 5 species of freshwater fish, i.e., Esomus metallicus, Puntius brevis, Anabas testudineus, Parambassis siamensis, and Carassius auratus, in Chiang Mai province, Thailand. Read More

    Development of Urinary Bladder Pre-Neoplasia by Schistosoma haematobium Eggs and Chemical Carcinogen in Mice.
    Korean J Parasitol 2017 Feb 28;55(1):21-29. Epub 2017 Feb 28.
    Department of Parasitology and Tropical Medicine, Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul 03080, Korea.
    Schistosoma haematobium is a biocarcinogen of human urinary bladder (UB). The present study investigated developing UB cancer mouse model by injecting S. haematobium eggs into the bladder wall and introduction of chemical carcinogens. Read More

    Molecular and Structural Characterization of the Tegumental 20.6-kDa Protein in Clonorchis sinensis as a Potential Druggable Target.
    Int J Mol Sci 2017 Mar 4;18(3). Epub 2017 Mar 4.
    Division of Malaria and Parasitic Diseases, Centre for Immunology and Pathology, Korea National Research Institute of Health, Chungbuk 28159, Korea.
    The tegument, representing the membrane-bound outer surface of platyhelminth parasites, plays an important role for the regulation of the host immune response and parasite survival. A comprehensive understanding of tegumental proteins can provide drug candidates for use against helminth-associated diseases, such as clonorchiasis caused by the liver fluke Clonorchis sinensis. However, little is known regarding the physicochemical properties of C. Read More

    Apropos: critical analysis of molluscicide application in schistosomiasis control programs in Brazil.
    Infect Dis Poverty 2017 Mar 7;6(1):54. Epub 2017 Mar 7.
    Key Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, 117 Yangxiang, Meiyuan, Wuxi City, Jiangsu Province, 214064, China.
    Schistosomiasis is a snail-transmitted infectious disease affecting over 200 million people worldwide. Snail control has been recognized as an effective approach to interrupt the transmission of schistosomiasis, since the geographic distribution of this neglected tropical disease is determined by the presence of the intermediate host snails. In a recent Scoping Review published in Infectious Diseases of Poverty, Coelho and Caldeira performed a critical review of using molluscicides in the national schistosomiasis control programs in Brazil. Read More

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