1,266 results match your criteria Travel Medicine and Vaccination


Monitoring of human coronaviruses in Belgian primary care and hospitals, 2015-20: a surveillance study.

Lancet Microbe 2021 Mar 27;2(3):e105-e114. Epub 2021 Jan 27.

National Influenza Centre, Sciensano, Brussels, Belgium.

Background: Seasonal human coronaviruses (hCoVs) broadly circulate in humans. Their epidemiology and effect on the spread of emerging coronaviruses has been neglected thus far. We aimed to elucidate the epidemiology and burden of disease of seasonal hCoVs OC43, NL63, and 229E in patients in primary care and hospitals in Belgium between 2015 and 2020. Read More

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Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study.

Eur J Cancer 2021 Apr 6;150:190-202. Epub 2021 Apr 6.

Policlinico Universitario Campus Bio-Medico, Rome, Italy.

Background: Despite high contagiousness and rapid spread, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to heterogeneous outcomes across affected nations. Within Europe (EU), the United Kingdom (UK) is the most severely affected country, with a death toll in excess of 100,000 as of January 2021. We aimed to compare the national impact of coronavirus disease 2019 (COVID-19) on the risk of death in UK patients with cancer versus those in continental EU. Read More

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Determinants of intention to get vaccinated against COVID-19 among healthcare personnel in hospitals in Greece.

Infect Dis Health 2021 Mar 31. Epub 2021 Mar 31.

Pathophysiology Department, Medical School, National and Kapodistrian University of Athens, 11527, Greece.

Background: To investigate intention rates to get vaccinated against COVID-19 among healthcare personnel (HCP) in Greece.

Methods: Cross-sectional survey.

Results: The response rate was 14. Read More

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[Travelling with children and adolescents with rheumatic diseases].

Z Rheumatol 2021 Apr 27. Epub 2021 Apr 27.

Abteilung für Pädiatrische Infektiologie und Rheumatologie, Klinik für Allgemeine Kinder- und Jugendmedizin, Universitätsklinikum Freiburg, Mathildenstr. 1, 79106, Freiburg, Deutschland.

Due to the underlying disease and immunosuppressive treatment, pediatric patients with rheumatic diseases are at increased risk for (long distance) travel-related health problems. A pretravel comprehensive consultation is therefore strongly recommended. Whether a child with rheumatic disease is sufficiently fit for travel essentially depends on the disease activity, the age of the child and the intended travel destination. Read More

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How geographic access to care shapes disease burden: The current impact of post-exposure prophylaxis and potential for expanded access to prevent human rabies deaths in Madagascar.

PLoS Negl Trop Dis 2021 Apr 26;15(4):e0008821. Epub 2021 Apr 26.

Boyd Orr Centre for Population and Ecosystem Health, Institute of Biodiversity, Animal Health and Comparative Medicine, University of Glasgow, Glasgow, United Kingdom.

Background: Post-exposure prophylaxis (PEP) is highly effective at preventing human rabies deaths, however access to PEP is limited in many rabies endemic countries. The 2018 decision by Gavi to add human rabies vaccine to its investment portfolio should expand PEP availability and reduce rabies deaths. We explore how geographic access to PEP impacts the rabies burden in Madagascar and the potential benefits of improved provisioning. Read More

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Impact of COVID-19 on routine immunisation in South-East Asia and Western Pacific: Disruptions and solutions.

Lancet Reg Health West Pac 2021 Apr 21:100140. Epub 2021 Apr 21.

Sanofi Pasteur, 38 Beach Road, #18-11 South Beach Tower, Singapore 189767, Singapore.

Background: Data on COVID-19-induced disruption to routine vaccinations in the South-East Asia and Western Pacific regions (SEAR/WPR) have been sparse. This study aimed to quantify the impact of COVID-19 on routine vaccinations by country, antigen, and sector (public or private), up to 1 June 2020, and to identify the reasons for disruption and possible solutions.

Methods: Sanofi Pasteur teams from 19 countries in SEAR/WPR completed a structured questionnaire reporting on COVID-19 disruptions for 13-19 routinely delivered antigens per country, based on sales data, government reports, and regular physician interactions. Read More

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Costs associated with COVID-19 in healthcare personnel in Greece: a cost-of-illness analysis.

J Hosp Infect 2021 Apr 21. Epub 2021 Apr 21.

Faculty of Social and Political Sciences, University of Peloponnese, Corinth, Greece; Health Policy Institute, Athens, Greece.

Background: Healthcare personnel (HCP) are at increased risk for SARS-CoV-2 infection.

Aim: To estimate the costs related to COVID-19 exposure and infection among HCP in Greece.

Methods: Data were retrieved from the national database of SARS-CoV-2 infections and from the database of HCP exposed to COVID-19. Read More

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Preventive measures, risk behaviour and the most common health problems in Czech travellers: a prospective questionnaire study in post-travel clinic outpatients.

Epidemiol Mikrobiol Imunol 2021 ;70(1):32-41

Objective:  The aim of this study was to evaluate attitudes towards the available preventive measures, risk behaviour and health problems in Czech travellers to tropical and subtropical regions.

Materials And Methods:  The prospective study included patients of all ages with a history of recent travel to risky countries who presented to the post-travel clinic of the Hospital Na Bulovce in Prague within two months after return, from February 2009 to June 2018. The data were collec-ted through a questionnaire survey and from electronic medical records. Read More

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Cross-sectional analysis of vaccine intention, perceptions and hesitancy across Latin America and the Caribbean.

Travel Med Infect Dis 2021 Apr 13:102059. Epub 2021 Apr 13.

Red Internacional en Salud Colectiva y Salud Intercultural, México, Mexico; Unidad para la Generación y Síntesis de Evidencias en Salud, Universidad San Ignacio de Loyola (USIL), Lima, Peru. Electronic address:

Background: Determinants of vaccine acceptance are multifactorial, complex, and in most cases, context-dependent. We determined the prevalence of COVID-19 vaccination intention (VI) and fear of its adverse effects (FAE) as well as their associated factors in Latin America and the Caribbean (LAC).

Methods: We conducted a secondary cross-sectional analysis of a database collected by the University of Maryland and Facebook. Read More

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Efficacy of one-dose intramuscular rabies vaccine as pre-exposure prophylaxis in travellers.

J Travel Med 2021 Apr 10. Epub 2021 Apr 10.

Research School of Population Health, Australian National University, Canberra, Australia.

Background: Current guidelines for rabies pre-exposure prophylaxis (PrEP) recommend multiple vaccine doses. Travellers sometimes present for pre-travel consultation with insufficient time to complete standard PrEP schedules. We investigated the efficacy of one-dose intramuscular (IM) vaccine in priming the immune system (as PrEP) by measuring antibody response to simulated post-exposure prophylaxis (PEP). Read More

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Diagnosis and Management of Vaccine-Related Thrombosis following AstraZeneca COVID-19 Vaccination: Guidance Statement from the GTH.

Hamostaseologie 2021 Apr 1. Epub 2021 Apr 1.

Institut für Immunologie und Transfusionsmedizin, Universitätsmedizin Greifswald, Greifswald, Germany.

The COVID-19 pandemic is an ongoing global healthcare crisis. Based on reports of atypically located thromboses following vaccination with the AstraZeneca COVID-19 vaccine, the Society of Thrombosis and Haemostasis Research (GTH) has issued guidance statements on the recognition, diagnosis, and treatment of this rare complication. It shares pathophysiological features with heparin-induced thrombocytopenia (HIT) and is referred to as vaccine-induced prothrombotic immune thrombocytopenia (VIPIT). Read More

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Long-Term Immunogenicity of Live Oral Cholera Vaccine CVD 103-HgR in Adolescents Aged 12-17 Years in the United States.

Am J Trop Med Hyg 2021 Apr 5. Epub 2021 Apr 5.

3Emergent Travel Health, Inc., Redwood City, California.

As part of a phase 4, randomized, double-blind, placebo-controlled trial to assess the immunogenicity and safety of PXVX0200 in children and adolescents aged 2-17 years, a subset of 73 adolescent subjects aged 12-17 years was followed up for 2 years after vaccination and had blood collected for antibody assays on days 1, 11, 29, 91, 181, 365, 547, and 730. Endpoints included serum vibriocidal antibody (SVA) seroconversion, defined as a 4-fold or greater rise in antibody titer over baseline; geometric mean titers (GMTs); and geometric mean fold increase (GMFI) over baseline. Serum vibriocidal antibody seroconversion persisted in most subjects, with a rate of 64. Read More

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Inadequate Measles, Mumps, Rubella, and Varicella Immunity Among Employees.

J Prim Care Community Health 2021 Jan-Dec;12:21501327211005902

Crossover Health, San Clemente, CA, USA.

Objectives: The purpose of this cohort study was to evaluate measles, mumps, rubella (MMR), and varicella immunity among a population of adult employees receiving primary care in an employer-sponsored health center.

Methods: Participants were eligible for MMR and varicella immunity screening if they were an employee receiving primary care in an employer-sponsored health center between January 1, 2019 and November 1, 2020 who could not provide proof of immunization and 1) had it recommended by their provider, 2) specifically requested immunity testing (often because they had heard of measles outbreaks in their country of origin), or 3) were seen for an immigration physical for their Green Card application.

Results: Overall, 3494 patients were screened for their MMR immunity. Read More

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A Longitudinal Study Regarding the Health Profile of the 2017 South African Hajj Pilgrims.

Int J Environ Res Public Health 2021 03 31;18(7). Epub 2021 Mar 31.

The Global Centre for Mass Gatherings Medicine, Ministry of Health, Riyadh 12341, Saudi Arabia.

The Hajj mass gathering annually attracts over two million Muslim pilgrims worldwide to the Kingdom of Saudi Arabia (KSA). We aimed to establish demographics and health profiles for the South African pilgrims performing the 2017 Hajj. This is a longitudinal survey-based study conducted on 1138 adult South African pilgrims in two phases (during and post-Hajj). Read More

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Travelers' Attitudes, Behaviors, and Practices on the Prevention of Infectious Diseases: A Study for Non-European Destinations.

Int J Environ Res Public Health 2021 03 18;18(6). Epub 2021 Mar 18.

Department of Health Sciences, University of Florence, 50134 Florence, Italy.

Background: The aim of this study was to improve our comprehension of the attitudes, behaviors, and practices related to the health risks of travel to non-European destinations.

Methods: This cross-sectional study utilized an online questionnaire disseminated through social networks.

Results: About 79% of the respondents reported that they informed themselves or would inform themselves about travel-related health risks before departure. Read More

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COVID-19 vaccination campaign in Nepal, emerging UK variant and futuristic vaccination strategies to combat the ongoing pandemic.

Travel Med Infect Dis 2021 Mar 27;41:102037. Epub 2021 Mar 27.

Grupo de Investigación Biomedicina, Faculty of Medicine, Fundacion Universitaria Autonoma de Las Americas, Pereira, Risaralda, Colombia; School of Medicine, Universidad Privada Franz Tamayo (UNIFRANZ), Cochabamba, Bolivia. Electronic address:

With the emergence of the new variants of concern (VOC) of the SARS-CoV-2, the efficacy of certain vaccines against them requires further research and considerations for future scenarios of COVID-19 vaccination. The vaccines' lack of efficacy against VOC will pose at risk to the vaccinated population and is a public health threat. In this commentary, we discuss Nepal's recent experiences and expectations regarding the confirmation of VOC B. Read More

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Invasive pneumococcal disease among adults with hematological and solid organ malignancies: A population-based cohort study.

Int J Infect Dis 2021 Mar 26;106:237-245. Epub 2021 Mar 26.

Amsterdam UMC, University of Amsterdam, Centre of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Amsterdam Institute for Infection and Immunity, Meibergdreef 9, Amsterdam, The Netherlands.

Objectives: To determine the risk of invasive pneumococcal disease (IPD) in adult cancer patients stratified by type of underlying malignancy, age, and capsular serotype and to assess herd effects of childhood pneumococcal vaccination.

Methods: All adult IPD cases reported to the Dutch pneumococcal surveillance system between 2004 and 2016 were included in this study. IPD incidence rates (IR) stratified by subtype of malignancy were calculated per 100 000 patient-years of follow-up. Read More

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Japanese encephalitis vaccine cost: a major reason to be vaccinated in Bali.

Authors:
I Md Ady Wirawan

J Travel Med 2021 Mar 27. Epub 2021 Mar 27.

Department of Public Health and Preventive Medicine, Faculty of Medicine, Udayana University, Bali, Indonesia.

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Full immunization coverage and associated factors among children age 12-23 months in Ethiopia: systematic review and meta-analysis of observational studies.

Hum Vaccin Immunother 2021 Mar 24:1-10. Epub 2021 Mar 24.

Department of Psychiatric Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

: Millions of children in developing countries remained unvaccinated and under-vaccinated. This study was aimed to determine the pooled full vaccination coverage and associated factors in Ethiopia.: This review and meta-analysis were included observational studies conducted from 2013 to 2020. Read More

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Association of clinical characteristics and lifestyle factors with fecal S100/calgranulin concentrations in healthy dogs.

Vet Med Sci 2021 Mar 10. Epub 2021 Mar 10.

Gastrointestinal Laboratory, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.

Background: Fecal S100/calgranulin (S100A12 and calprotectin) concentrations are useful markers of gastrointestinal inflammation in dogs. In people, fecal S100/calgranulin concentrations are affected by age, obesity, diet and other lifestyle factors. Knowledge about the effects of such factors on fecal S100/calgranulin concentrations in dogs is currently scarce. Read More

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Risk Factors of Measles Outbreak Among Students of Mizan-Tepi University, Tepi Campus, Southwest Ethiopia.

Infect Drug Resist 2021 11;14:963-970. Epub 2021 Mar 11.

School of Pharmacy, Department Pharmacology and Pharmaceutical Chemistry College of Medicine and Health Sciences, Mizan-Tepi University, Mizan-Aman, Ethiopia.

Background: Measles is a serious respiratory disease that is spread easily through coughing and sneezing of the measles virus for which humans are the only reservoir. Even though prevention and elimination strategies had been implemented, the outbreaks of measles infection quietly occur in different parts of the world. As of November 2019 a suspected measles outbreak was reported from Tepi campus student's clinic. Read More

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Sexual behaviours associated with incident high-risk anal human papillomavirus among gay and bisexual men.

Sex Transm Infect 2021 Mar 16. Epub 2021 Mar 16.

The Kirby Insitute, UNSW Sydney, Sydney, New South Wales, Australia.

Objective: High-risk human papillomavirus (HRHPV) causes anal cancer, which disproportionately affects gay and bisexual men (GBM). We examined sexual behaviours associated with incident anal HRHPV in an observational cohort study of GBM in Sydney, Australia.

Methods: GBM aged 35 years and above were enrolled in the Study of the Prevention of Anal Cancer. Read More

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Impact of COVID-19 pandemic on vaccination coverage among children aged 15 to 23 months at Dessie town, Northeast Ethiopia, 2020.

Hum Vaccin Immunother 2021 Mar 15:1-9. Epub 2021 Mar 15.

Department of Comprehensive Nursing, School of Nursing and Midwifery, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

: Disturbances are occurring in healthcare, trade, and travel, with countries closing off their borders due to the pandemic of coronavirus disease 2019(COVID-19) in the world. The pandemic has its impact on the delivery of important health services, including vaccinations. This study aimed to assess the impact of COVID-19 on vaccination coverage among children aged 15-23 months. Read More

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If I told you that there is no need for yellow fever vaccine booster would you still come to the travel clinic?: a cross-sectional study.

Trop Dis Travel Med Vaccines 2021 Mar 12;7(1). Epub 2021 Mar 12.

Global Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisboa, Portugal.

Background: Yellow Fever (YF) immunization required a single dose vaccine with boosters every 10 years. After International Health Regulation (IHR) amendment annex 7 (July 2016), it was accepted that a single dose confers lifelong immunity. Since pre-travel advice is as important as vaccination when traveling, it is essential to clarify why travelers come to a travel health consultation, with the possibility of IHR amendment having a negative impact on travelers' health. Read More

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Comparison of equivalent fractional vaccine doses delivered by intradermal and intramuscular or subcutaneous routes: A systematic review.

Travel Med Infect Dis 2021 Mar 9:102007. Epub 2021 Mar 9.

Centre for Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Amsterdam UMC, Amsterdam Infection & Immunity, Amsterdam Public Health, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, the Netherlands. Electronic address:

Background: For certain vaccines, dosing can be reduced by intradermal (ID) immunization without loss of immunogenicity, as an alternative to standard routes of administration. However, a certain level of dose-sparing might also be achieved by reducing doses of intramuscular (IM) or subcutaneous (SC) vaccines.

Method: We conducted a systematic review comparing identical reduced amounts of antigen delivered by either ID, or IM/SC routes (PROSPERO registration no. Read More

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Epidemiology and clinical features of COVID-19 outbreaks in aged care facilities: A systematic review and meta-analysis.

EClinicalMedicine 2021 Mar 1;33:100771. Epub 2021 Mar 1.

Central Queensland University, Rockhampton, Australia.

Background: COVID-19 outbreaks in aged care facilities (ACFs) often have devastating consequences. However, epidemiologically these outbreaks are not well defined. We aimed to define such outbreaks in ACFs by systematically reviewing literature published during the current COVID-19 pandemic. Read More

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Immunogenicity and safety of a nine-valent human papillomavirus vaccine in women 27-45 years of age compared to women 16-26 years of age: An open-label phase 3 study.

Vaccine 2021 May 3;39(20):2800-2809. Epub 2021 Mar 3.

Merck & Co., Inc., Kenilworth, NJ, USA. Electronic address:

Background: Efficacy of the nine-valent human papillomavirus (9vHPV; HPV types 6/11/16/18/31/33/45/52/58) vaccine was demonstrated in a phase 3 study in women 16-26 years of age. We present a phase 3 immunogenicity and safety study of the 9vHPV vaccine in women 27-45 versus 16-26 years of age.

Methods: This international, open-label study (NCT03158220) was conducted in women 16-45 years of age. Read More

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Health Problems During and After Travel: A Prospective Observational Study in a Travel Clinic in Portugal.

Acta Med Port 2021 Mar 3. Epub 2021 Mar 3.

Global Health and Tropical Medicine. Instituto de Higiene e Medicina Tropical. Universidade NOVA de Lisboa. Lisboa. Portugal.

Introduction: In order to improve the health of travellers during travel it is important to better understand the health problems faced by travellers in different destinations. The main objective of this study was to characterise the perceived health problems of travellers during and up to six months after travel on a pre-travel clinic in Lisbon, Portugal.

Material And Methods: This is a prospective observational study. Read More

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Implementing digital passports for SARS-CoV-2 immunization in Canada.

CMAJ 2021 04 2;193(14):E486-E488. Epub 2021 Mar 2.

Department of Medicine (Wilson), School of Epidemiology and Public Health, University of Ottawa; Bruyère Research Institute and Ottawa Hospital Research Institute (Wilson); Faculty of Law (Flood), Common Law Section, University of Ottawa; University of Ottawa Centre for Health Law Policy & Ethics (Flood), Ottawa, Ont.

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