1,563 results match your criteria Traumatic Ulcers


Advances in dermoepidermal skin substitutes for diabetic foot ulcers.

Curr Vasc Pharmacol 2019 Apr 8. Epub 2019 Apr 8.

Diabetes Centre-Diabetic Foot Clinic, Second Department of Internal Medicine, Democritus University of Thrace, University Hospital of Alexandroupolis. Greece.

Diabetic foot ulcers (DFUs) are one of the major complications of diabetes, representing a leading cause of hospitalisation and non-traumatic lower limb amputations. Multidisciplinary management, patient education, glucose control, debridement, off-loading, infection control, and adequate perfusion are the mainstays of standard care. Despite all these, at least 30% of DFUs fail to heal within 20 weeks. Read More

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http://dx.doi.org/10.2174/1570161117666190408170144DOI Listing
April 2019
5 Reads

An unusual case of post-trauma polymicrobial cutaneous diphtheria.

Infection 2019 Apr 5. Epub 2019 Apr 5.

Department of Orthopedics, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India.

We report a rare case of post-traumatic cutaneous diphtheria in a patient referred from a hospital in rural India. The diagnosis of cutaneous diphtheria was confirmed by the isolation of Corynebacterium diphtheriae cultured from the ulcer of the leg, along with Staphylococcus aureus, Streptococcus pyogenes, and Arcanobacterium haemolyticum. The patient was kept on isolation and treated with erythromycin for 14 days without antitoxin. Read More

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http://dx.doi.org/10.1007/s15010-019-01300-xDOI Listing

Traumatic vs non-traumatic spinal cord injury: A comparison of primary rehabilitation outcomes and complications during hospitalization.

J Spinal Cord Med 2019 Apr 3:1-7. Epub 2019 Apr 3.

c Department of Neurology , Haukeland University Hospital , Bergen , Norway.

Objective: To compare outcome for patients with traumatic (TSCI) and non-traumatic spinal cord injuries (NTSCI) after primary rehabilitation regarding neurological improvement measured by the American Spinal Injury Association Impairment Scale (AIS), length of stay and complications.

Design: Retrospective comparative cohort study on patients with TSCI and NTSCI, hospitalized during a ten-year period at Haukeland University Hospital, Norway. Impairment, length of stay and complications during first in-patient rehabilitation period were analyzed. Read More

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http://dx.doi.org/10.1080/10790268.2019.1598698DOI Listing
April 2019
1 Read

Effectiveness of Tragacanth Gel Cushions in Prevention of Pressure Ulcer in Traumatic Patients: a Randomized Controlled Trial.

J Caring Sci 2019 Mar 1;8(1):45-49. Epub 2019 Mar 1.

Department of Nursing, Nursing and Midwifery School, Iranian Research Center on Healthy Aging, Sabzevar University of Medical Sciences, Sabzevar, Iran.

Introduction: Pressure ulcer is one of the most common and painful complications in patients admitted to intensive care units (ICUs). This study aimed to compare the effects of tragacanth gel cushions and foam-filled ones on the prevention of pressure ulcers. This triple-blind, randomized, clinical trial was performed on 94 patients admitted to the ICU of Taleqhani Hospital of Mashhad, Iran. Read More

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http://dx.doi.org/10.15171/jcs.2019.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428161PMC
March 2019
13 Reads

Clinical, laboratory and ultrasonographic findings in 87 cows with type-4 abomasal ulcer.

BMC Vet Res 2019 Mar 25;15(1):100. Epub 2019 Mar 25.

Department of Farm Animals, Vetsuisse-Faculty, University of Zurich, Winterthurerstrasse 260, CH-8057, Zurich, Switzerland.

Background: This study evaluated the clinical, laboratory, ultrasonographic and pathological findings in 87 cows aged 2 to 10 years (4.5 ± 1.5 years) with type-4 abomasal ulcer. Read More

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https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-
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http://dx.doi.org/10.1186/s12917-019-1844-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434897PMC
March 2019
4 Reads

Mouse Model of Pressure Ulcers After Spinal Cord Injury.

J Vis Exp 2019 Mar 9(145). Epub 2019 Mar 9.

Department of Biomedical Engineering, Rutgers University;

Pressure ulcers (PUs) are common debilitating complications of traumatic spinal cord injury (SCI) and tend to occur in soft tissues around bony prominences. There is, however, little known about the impact of SCI on skin wound healing in the context of animal models in controlled experimental settings. In this study, a simple, non-invasive, reproducible and clinically relevant mouse model of PUs in the context of complete SCI is presented. Read More

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http://dx.doi.org/10.3791/58188DOI Listing

Uncertain progress in Swiss perioperative mortality 1998-2014 for 22 operation groups.

Swiss Med Wkly 2019 03 24;149:w20034. Epub 2019 Mar 24.

Institute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland.

Background: The perioperative mortality rate (POMR) is used as a quality indicator to monitor health care system performance at regional and national levels. The Swiss Federal Office of Public Health publishes national in-hospital mortality rates for several indicator conditions and indicator operation types (IORs). We investigated long-term time trends of POMRs from 1998-2014. Read More

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http://dx.doi.org/10.4414/smw.2019.20034DOI Listing
March 2019
2 Reads

Timing of Tracheostomy Placement among Children with Severe Traumatic Brain Injury: A Propensity-Matched Analysis.

J Trauma Acute Care Surg 2019 Mar 13. Epub 2019 Mar 13.

Division of Pediatric General Surgery, UCSF Benioff Children's Hospital Oakland, Oakland, CA.

Background: Early tracheostomy has been associated with shorter hospital stay and fewer complications in adult trauma patients. Guidelines for tracheostomy have not been established for children with severe TBI. The purpose of this study was to 1) define nationwide trends in time to extubation and time to tracheostomy; and 2) determine if early tracheostomy is associated with decreased length of stay and fewer complications in children with severe TBI. Read More

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http://dx.doi.org/10.1097/TA.0000000000002237DOI Listing
March 2019
9 Reads

Adjuvant antibiotic loaded bio composite in the management of diabetic foot osteomyelitis - A multicentre study.

Foot (Edinb) 2019 Jan 11;39:22-27. Epub 2019 Jan 11.

Trauma and Orthopaedics Department, Wythenshawe Hospital, Manchester University Foundation Trust, United Kingdom. Electronic address:

Background: Diabetic foot ulcers are associated with a high morbidity and are common cause of non-traumatic lower limb amputations. The effect of debridement and the use of an adjuvant local antibiotic carrier in the treatment of diabetic foot ulcers with osteomyelitis was evaluated.

Methods: A retrospective review of patients with diabetic foot ulceration and osteomyelitis treated by debridement with adjuvant local antibiotic was performed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09582592183016
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http://dx.doi.org/10.1016/j.foot.2019.01.005DOI Listing
January 2019
8 Reads

Descending thoracic endovascular aortic repair does not require cardiothoracic surgery support.

Vascular 2019 Mar 13:1708538119836331. Epub 2019 Mar 13.

Division of Vascular Surgery, NYU Langone Hospital-Brooklyn, Brooklyn, NY, USA.

Objective: Descending thoracic endovascular aneurysm repair (D-TEVAR) is often performed by vascular surgeons. At many institutions, cardiothoracic surgery support is required for an elective TEVAR to take place. Oftentimes, this means a dedicated cardiopulmonary bypass team must be available. Read More

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http://dx.doi.org/10.1177/1708538119836331DOI Listing
March 2019
6 Reads

Four-year review of admissions to a South African regional hospital general surgery department.

S Afr Med J 2019 Jan 31;109(2):122-126. Epub 2019 Jan 31.

Department of Surgery, Worcester Hospital and Ukwanda Centre for Rural Health, Stellenbosch University, Cape Town, South Africa.

Background: There are limited published data describing surgical admissions at a regional hospital level in the South African (SA) context.

Objectives: To retrospectively review data from an electronic discharge summary  database at a regional SA hospital from 2012 to 2016 to describe the burden of surgical disease by analysing characteristics of the patients admitted.

Methods: All discharge summary records for the 4-year period were reviewed after extraction from a database created for the surgery department. Read More

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http://dx.doi.org/10.7196/SAMJ.2019.v109i2.13433DOI Listing
January 2019
3 Reads

Potential prognostic factors for delayed healing of common, non-traumatic skin ulcers: A scoping review.

Int Wound J 2019 Feb 28. Epub 2019 Feb 28.

NIHR Greater Manchester Patient Safety Translational Research Centre, The University of Manchester, Manchester, UK.

Healing of non-traumatic skin ulcers is often suboptimal. Prognostic tools that identify people at high risk of delayed healing within the context of routine ulcer assessments may improve this, but robust evidence on which factors to include is lacking. Therefore, we scoped the literature to identify which potentially prognostic factors may warrant future systematic reviews and meta-analyses. Read More

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http://dx.doi.org/10.1111/iwj.13100DOI Listing
February 2019
4 Reads

Photobiomodulation therapy modulates epigenetic events and NF-κB expression in oral epithelial wound healing.

Lasers Med Sci 2019 Feb 28. Epub 2019 Feb 28.

Department of Oral Pathology, School of Dentistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.

The aim of this study was to evaluate the effect of photobiomodulation therapy (PBMT) on histone 3 acetylation (acH3) and NF-κB expression during oral ulcer healing. A total of 48 male Wistar rats were divided into control group (CG) and PBMT group (n = 24 each). Traumatic ulcers were created in the dorsum of the rats' tongue with a punch tool. Read More

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http://dx.doi.org/10.1007/s10103-019-02745-0DOI Listing
February 2019

Management options for low-dose methotrexate-induced oral ulcers: A systematic review.

Med Oral Patol Oral Cir Bucal 2019 Mar 1;24(2):e181-e189. Epub 2019 Mar 1.

Entrerríos s/n, Santiago de Compostela, C.P. 15782, Spain,

Background: Oral ulcers caused by methotrexate (MTX) at low doses are a known side effect of this drug. Although increasingly more patients are medicated with MTX, these painful ulcers, without traumatic origin and resistant to any type of treatment, are not usually identified by health professionals as a side effect of the medication.

Material And Methods: In the absence of a consensus protocol for the effective treatment of oral lesions produced by MTX, the objective of this article was to review and analyse the information from articles related to oral ulcers produced by low-dose MTX and to record the clinical management performed and the MTX dose given to the patient. Read More

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http://dx.doi.org/10.4317/medoral.22851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441606PMC

Health factors and spinal cord injury: a prospective study of risk of cause-specific mortality.

Spinal Cord 2019 Feb 25. Epub 2019 Feb 25.

College of Health Professions, Medical University of South Carolina, Charleston, SC, 29403, USA.

Study Design: Prospective cohort study.

Objectives: Identify the risk and protective factors of all-cause and cause-specific mortality among persons with traumatic spinal cord injury (SCI).

Setting: Rehabilitation specialty hospital in the Southeastern United States. Read More

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http://dx.doi.org/10.1038/s41393-019-0264-6DOI Listing
February 2019
1 Read

Acute abdomen in drug abusers.

Authors:
L Hána M Ryska

Rozhl Chir Winter 2019;98(1):14-17

Introduction: Acute abdomen is one of the most important issues in abdominal surgery. Our study aims to describe the differences in clinical presentation of patients, in the course of their hospitalization, and in morbidity and mortality of patients with drug abuse; another aim is to describe our own experience with drug abusers with acute abdomen. Method: Patients with the history of drug abuse and with non-traumatic acute abdomen were included retrospectively to our set. Read More

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February 2019
1 Read

Evaluation of salivary tumour necrosis factor-alpha in patients with recurrent aphthous stomatitis.

Eur Oral Res 2018 Sep 1;52(3):157-161. Epub 2018 Sep 1.

Department of Oral Medicine and Radiology, A B Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, India.

Purpose: Present study was undertaken to evaluate and compare the salivary levels of tumour necrosis factor alpha (TNF-α) in subjects with RAS, traumatic ulcers (TUs) in the oral mucosa and in healthy controls.

Materials And Methods: Present study involved 90 participants of which 30 subjects were diagnosed with RAS, 30 subjects with TUs and 30 healthy controls grouped as group 1, group 2 and group 3 respectively. Unstimulated saliva was collected from the subjects through 'Spit Technique' and the estimation of TNF-α was done by enzyme linked immunosorbent assay. Read More

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http://dx.doi.org/10.26650/eor.2018.543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365135PMC
September 2018
1 Read

Prevalence of peripheral arterial disease among diabetic patients in Santo Domingo, Dominican Republic and associated risk factors.

Arch Med Sci Atheroscler Dis 2018 15;3:e35-e40. Epub 2018 Feb 15.

Shanghai Xin Hua Hospital affiliated to the Shanghai Jiao Tong University, School of Medicine, Shanghai, China.

Introduction: Peripheral arterial disease (PAD) is a major risk factor of coronary artery disease and a major complication of atherosclerosis. Peripheral arterial disease can be diagnosed with simple and low cost techniques. There are major risk factors of PAD that have been studied for different countries. Read More

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http://dx.doi.org/10.5114/amsad.2018.73527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374585PMC
February 2018
2 Reads

Gastroseal: A Novel Stent Design for the Management of Post-Bariatric Surgery Leaks.

ACG Case Rep J 2018 5;5:e85. Epub 2018 Dec 5.

Bariatric Surgery Unit, General Surgery Department, Cairo University Hospital, Cairo, Egypt.

Bariatric surgery leaks remain a dreaded complication with ominous consequences. Fully covered stents have shown efficacy in the treatment of leaks; however, stent migration remains a major drawback. Ultra-large stents have shown reduced rates of migration and coapt better against the walls, but deep ulcers occur in almost all patients, as well as frequent severe intolerance, bleeding, and perforation. Read More

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http://dx.doi.org/10.14309/crj.2018.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358575PMC
December 2018

The role of thoracic endovascular repair in elective, symptomatic and ruptured thoracic aortic diseases.

Eur J Cardiothorac Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Vascular Surgery, University Aortic Center of the Ludwig-Maximilian University Munich, Munich, Germany.

Objectives: Thoracic endovascular aortic repair (TEVAR) has emerged as a safe procedure in the treatment of a wide spectrum of descending thoracic aortic pathologies, with satisfactory results both in elective and urgent settings. We investigated the results of our elective, urgent and emergency TEVAR interventions.

Methods: A single-centre retrospective analysis of all consecutive patients undergoing TEVAR from 2010 to 2016 was performed. Read More

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http://dx.doi.org/10.1093/ejcts/ezy482DOI Listing
February 2019
4 Reads

Biomarkers in Spinal Cord Injury: Prognostic Insights and Future Potentials.

Front Neurol 2019 29;10:27. Epub 2019 Jan 29.

Department of Neurosurgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt.

Spinal Cord Injury (SCI) is a major challenge in Neurotrauma research. Complex pathophysiological processes take place immediately after the injury and later on as the chronic injury develops. Moreover, SCI is usually accompanied by traumatic injuries because the most common modality of injury is road traffic accidents and falls. Read More

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http://dx.doi.org/10.3389/fneur.2019.00027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361789PMC
January 2019

Oral tuberculosis mimicking a traumatic denture ulcer.

J Prosthet Dent 2019 Feb 26;121(2):225-228. Epub 2018 Oct 26.

Associate Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea. Electronic address:

Tuberculosis (TB) of the oral cavity may be overlooked in the differential diagnosis of oral lesions and can be misdiagnosed and managed incorrectly. A 66-year-old man with complete dentures presented with a nonhealing mucosal ulcer in the upper lip. Despite the treatments performed by a local medical clinic, the ulcerative lesion on the denture-bearing area had not improved over 5 months. Read More

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http://dx.doi.org/10.1016/j.prosdent.2018.04.024DOI Listing
February 2019
2 Reads

In Vivo Assessment of Ascending and Arch Aortic Compliance.

Ann Vasc Surg 2019 Jan 30. Epub 2019 Jan 30.

Division of Vascular Surgery, Harbor-UCLA Medical Center, Torrance, CA; Division of Vascular Surgery, Long Beach Memorial Heart & Vascular Institute, Long Beach, CA.

Background: Dynamic compliance (Cd) of the adult thoracic ascending and arch aorta has had limited in vivo evaluation in patients with aortic disease. This study evaluates aortic compliance using intravascular ultrasound (IVUS) across a range of thoracic aortic diseases.

Methods: Seventy-nine patients undergoing thoracic aortic endovascular procedures had Cd measurements of the ascending aorta proximal to the origin of the brachiocephalic trunk and distal to the origin of the left common carotid artery using IVUS before endograft deployment. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.12.060DOI Listing
January 2019
13 Reads

Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.

Head Neck Pathol 2019 Mar 7;13(1):91-102. Epub 2019 Mar 7.

Department of Diagnostic and Biomedical Sciences, University of Texas at Houston Health Science Center School of Dentistry, Houston, TX, USA.

Ulcerated lesions of the oral cavity have many underlying etiologic factors, most commonly infection, immune related, traumatic, or neoplastic. A detailed patient history is critical in assessing ulcerative oral lesions and should include a complete medical and medication history; whether an inciting or triggering trauma, condition, or medication can be identified; the length of time the lesion has been present; the frequency of episodes in recurrent cases; the presence or absence of pain; and the growth of the lesion over time. For multiple or recurrent lesions the presence or history of ulcers on the skin, genital areas, or eyes should be evaluated along with any accompanying systemic symptoms such as fever, arthritis, or other signs of underlying systemic disease. Read More

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http://dx.doi.org/10.1007/s12105-018-0981-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405793PMC
March 2019
2 Reads

[Effects of nasogastric and percutaneous endoscopic gastrostomy tube feeding on the susceptibility of pulmonary infection in long-term coma patients with stroke or traumatic brain injury].

Zhonghua Yi Xue Za Zhi 2018 Dec;98(48):3936-3940

Intensive Care Unit, Tongzhou People's Hospital, Nantong 226300, China.

To investigate the effects of nasogastric tube (NGT) and percutaneous endoscopic gastrostomy (PEG) tube feeding on the susceptibility of pulmonary infection in long-term coma patients with stroke or traumatic brain injury. A total of 295 candidates who were in long-term coma after stroke or traumatic brain injury but without pulmonary infection and eligible for PEG catheterization were screened prospectively between January 2014 and February 2018. The patients were divided into PEG group (86 patients) and NGT group (209 patients) according to the choice of next-of-kin. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2018.48.006DOI Listing
December 2018
17 Reads

The relationship between body mass index and oral health status among Saudi adults: a cross-sectional study.

Community Dent Health 2019 Feb 25;36(1):217-222. Epub 2019 Feb 25.

Dental student, College of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh. Saudi Arabia.

Objective: To assess the relationship between body mass index (BMI) and the sum of decayed, missing and filled teeth (DMFT), periodontal pockets, and oral soft tissue variations.

Basic Research Design: A systematic sample of 250 people attending King Abdulaziz Medical City was included. The study was conducted using questionnaires and clinical examinations. Read More

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http://dx.doi.org/10.1922/CDH_4361Hamasha06DOI Listing
February 2019
2 Reads

Experimental model of oral ulcer in mice: Comparing wound healing in three immunologically distinct animal lines.

J Oral Maxillofac Pathol 2018 Sep-Dec;22(3):444

Department of Dentistry, Unichristus, Fortaleza, Ceará, Brazil.

Background: The oral wound healing is dependent of immune participation and the absence or augment of one specific immune profile can delayed wound healing.

Objectives: So, the objective of this study was t evaluate the wound healing of oral traumatic ulcer (OTU) in cheek mucosa of swiss, balb/c and c57bl6J mice.

Materials And Methods: A total of 144 mice (25-30g) were distributed in three groups: swiss ( = 48), balb/c ( = 48) and c57bl/6j ( = 48). Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_144_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306613PMC
January 2019
8 Reads

Neuropathic diabetic foot ulcers treated with cerium dioxide nanoparticles: A case report.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):228-234. Epub 2018 Aug 29.

Zabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Zabolotny Str., 154, Kyiv, 03680, Ukraine; LCL "DIAPROF", Svitlycky Str., 35, Kyiv, 04123, Ukraine.

Wound healing in diabetes is frequently impaired and its treatment remains a challenge. The ability of topical application of cerium (Ce) dioxide nanoparticles (CNPs) to accelerate wound healing in an animal model provides a rationale to develop this technology for use in humans affected by traumatic injury, diabetes and burns. We first described a case report of successful topical treatment of neuropathic diabetic foot ulcers with novel gel containing CNPs. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.08.027DOI Listing
August 2018
2 Reads

Comment on "'Chronic traumatic ulcer of lateral tongue' - An underestimated 'oral potentially malignant disorder'?"

Oral Oncol 2019 Feb 26;89:155-156. Epub 2018 Dec 26.

Department of Oral Medicine, Dentistry College, Universidad Nacional de Córdoba, Argentina. Electronic address:

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http://dx.doi.org/10.1016/j.oraloncology.2018.12.026DOI Listing
February 2019

Association between thermal threshold abnormalities and peripheral artery disease in patients with type 2 diabetes.

Medicine (Baltimore) 2018 Dec;97(51):e13803

Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital.

Both diabetic peripheral neuropathy and peripheral arterial disease (PAD) cause foot ulcers and often result in non-traumatic amputations in patients with type 2 diabetes. This study aimed to evaluate the association between clinical variables, PAD, and subclinical diabetic small fiber peripheral neuropathy detected by abnormal thermal thresholds of the lower extremities in patients with type 2 diabetes.We investigated 725 consecutive patients with type 2 diabetes (male/female: 372/353; mean age, 67 ± 11 years) who did not have apparent cardiovascular disease (including coronary artery disease, arrhythmia, and stroke) and who underwent the quantitative sensory test for thermal (warm and cold) thresholds of the lower limbs and ankle-brachial index (ABI)/toe-brachial index (TBI) examinations in 2015. Read More

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http://dx.doi.org/10.1097/MD.0000000000013803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319792PMC
December 2018
7 Reads

Current Available Cellular and Tissue-Based Products for Treatment of Skin Defects.

Adv Skin Wound Care 2019 Jan;32(1):19-25

At Brigham and Women's Hospital in Boston, Massachusetts, Yukun Liu, MD, was a Research Fellow at the time this manuscript was written; Adriana C. Panayi, MD, is a Research Fellow; Lauren R. Bayer, PA-C, is Clinical Director of the Wound Care Center; and Dennis P. Orgill MD, PhD is Director of the Wound Care Center, Department of Surgery, Brigham and Women's Hospital; and Professor of Surgery, Harvard Medical School. Acknowledgment: Dr Orgill is a consultant and/or receives research funding from Integra LifeSciences Corporation, the Musculoskeletal Research Foundation, Geistlich Corporation, Acell Corporation, and Professional Education and Research Incorporated. The authors have disclosed no other financial relationships related to this article. Submitted May 18, 2018; accepted June 29, 2018.

The occurrence of diabetic foot ulcers and venous leg ulcers is increasing because of aging population trends as well as increases in the number of people with diabetes and obesity. New technologies have been developed to treat these conditions, whereas other technologies previously designed for burns and traumatic wounds have been adapted. This article reviews the development of selected skin replacement technologies, particularly cellular and tissue-based products, highlighting their effectiveness on diabetic foot ulcers, venous leg ulcers, and burns. Read More

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http://Insights.ovid.com/crossref?an=00129334-201901000-0000
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http://dx.doi.org/10.1097/01.ASW.0000547412.54135.b7DOI Listing
January 2019
10 Reads

Malignant transformation of a non-healing traumatic wound on the lower extremity: A case report.

Int J Surg Case Rep 2018 22;53:468-470. Epub 2018 Nov 22.

Department of Plastic Surgery and Breast Surgery, Zealand University Hospital, Sygehusvej 10, 4000, Roskilde, Denmark.

Objective: Malignant transformation of chronic non-healing wounds is often overlooked. If a chronic wound fails to heal, or if there are changes in the characteristics of a wound, a biopsy should be performed.

Methods: This case is presented in line with SCARE guidelines. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183053
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http://dx.doi.org/10.1016/j.ijscr.2018.11.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275160PMC
November 2018
2 Reads

Endograft migration after thoracic endovascular aortic repair.

J Vasc Surg 2018 Dec 12. Epub 2018 Dec 12.

Department of Vascular and Endovascular Surgery, University Hospital Heidelberg, Heidelberg, Germany.

Objective: The objective of this study was to evaluate the incidence, timing, and potential risk factors of late endograft migration after thoracic endovascular aortic repair (TEVAR).

Methods: A retrospective analysis was conducted of 123 patients receiving TEVAR for thoracic aortic aneurysms (TAAs), dissections, penetrating aortic ulcer, intramural hematoma, or traumatic transection between January 2005 and December 2015 with a minimum imaging-based follow-up of 6 months. Imaging analysis was performed by three independent readers. Read More

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http://dx.doi.org/10.1016/j.jvs.2018.07.073DOI Listing
December 2018

Histopathological changes in major amputations due to diabetic foot - a review.

Rom J Morphol Embryol 2018 ;59(3):699-702

Discipline of Pharmacology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania;

Diabetes mellitus is the leading cause of non-traumatic amputations worldwide. Ulcer of the diabetic foot is one of the most prevalent lesions of diabetic patients and it occurs in the natural evolution of the disease as a tardive complication. Neuropathy is the main determinant of foot ulcer. Read More

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December 2018
4 Reads

Concentration of Costs Among High Utilizers of Health Care Services Over the First 10 Years After Spinal Cord Injury Rehabilitation: A Population-based Study.

Arch Phys Med Rehabil 2018 Nov 23. Epub 2018 Nov 23.

College of Health Professions, Medical University of South Carolina, Charleston, SC.

Objective: The purpose of this study was to (1) categorize individuals into high, medium, and low utilizers of health care services over a 10-year period after the onset of spinal cord injury (SCI) and (2) identify the pattern of causes of hospitalizations and the characteristics associated with high utilization.

Design: Retrospective analysis of self-report assessment linked to administrative data.

Setting: Data were collected from participants living in and utilizing hospitals in the state of South Carolina. Read More

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http://dx.doi.org/10.1016/j.apmr.2018.10.020DOI Listing
November 2018
2 Reads

Application of a paste-type acellular dermal matrix for coverage of chronic ulcerative wounds.

Arch Plast Surg 2018 Nov 15;45(6):564-571. Epub 2018 Nov 15.

Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University School of Medicine, Seoul, Korea.

Background: Chronic wounds occur due to failure of the normal healing process, associated with a lack of deposition of cellular components and a suitable microenvironment such as the extracellular matrix (ECM). Acellular dermal matrix (ADM) is viewed as an ECM substitute, and a paste-type ADM has recently been introduced. We hypothesized that CGPaste, an injectable paste-type ADM, could serve as a scaffold and promote wound healing. Read More

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http://dx.doi.org/10.5999/aps.2018.00605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258976PMC
November 2018
27 Reads

[Effectiveness comparison between proximal femoral nail anti-rotation and proximal femoral locking compression plate for intertrochanteric fracture in elderly patients combined with hemiplegia due to cerebral infarction].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 11;32(11):1411-1416

Department of Traumatic Orthopedics, the Affiliated Hospital of Chengde Medical University, Chengde Hebei, 067000, P.R.China.

Objective: To investigate the difference in the effectiveness between proximal femoral nail anti-rotation (PFNA) and proximal femoral locking compression plate (PFLCP) for intertrochanteric fracture in elderly patients combined with hemiplegia due to cerebral infarction.

Methods: The clinical data of 67 cases of intertrochanteric femoral fractures combined with hemiplegia due to cerebral infarction between October 2013 and January 2017 were retrospectively analyzed. Among them, 32 cases were treated with PFNA internal fixation (PFNA group), and 35 cases were treated with PFLCP internal fixation (PFLCP group). Read More

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http://dx.doi.org/10.7507/1002-1892.201805073DOI Listing
November 2018
4 Reads

Free flap and kickstand external fixator in foot and ankle soft tissue reconstruction. The versatility of a microsurgical-friendly application of an orthopedic device.

Injury 2018 Nov;49 Suppl 3:S105-S109

Division of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy.

Introduction: Foot and ankle are prone to injuries and often require free flap for complex soft tissue reconstruction due to the insufficiency of local soft tissue. Lower limb reconstruction can be commonly compromised by venous insufficiency, and the elevation of the limb represents a critical component of the postoperative care. This study aims to explore the versatility of combining free soft tissue flap reconstruction for complex foot and ankle defect with a temporary Kickstands External Fixator (KEF) placement. Read More

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http://dx.doi.org/10.1016/j.injury.2018.09.048DOI Listing
November 2018
2 Reads

Comprehensive Analysis of Long Noncoding RNAs and Messenger RNAs Expression Profiles in Patients with Marjolin Ulcer.

Med Sci Monit 2018 Nov 2;24:7828-7840. Epub 2018 Nov 2.

Department of Burns and Reconstructive Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland).

BACKGROUND Marjolin ulcer (MU) is an aggressive cutaneous malignancy. Typically, MU occurs over a period of time in post-burn and/or post-traumatic lesions and scars. However, the pathogenesis of scar carcinogenesis and MU development remains to be elucidated. Read More

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https://www.medscimonit.com/abstract/index/idArt/911177
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http://dx.doi.org/10.12659/MSM.911177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6228116PMC
November 2018
7 Reads

Two cases of chronic oral ulcers effectively treated with systemic corticosteroid therapy: Circumorificial plasmacytosis and traumatic ulcerative granuloma with stromal eosinophilia.

J Dermatol 2019 Jan 31;46(1):48-51. Epub 2018 Oct 31.

Department of Dermatology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Chronic oral ulcers are induced by various causative factors. Biopsy from an active site around ulceration is critical for both the definitive diagnosis and proper treatment. We report two cases of chronic oral ulcers, circumorificial plasmacytosis (CP) and traumatic ulcerative granuloma with stromal eosinophilia (TUGSE). Read More

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http://dx.doi.org/10.1111/1346-8138.14690DOI Listing
January 2019
2 Reads

An unexpected complication of a heterotopic ossified abdominal scar.

Ann Ital Chir 2018 Jun 12;7. Epub 2018 Jun 12.

Aim: Presentation and discussion of a case of heterotopic ossification of a vertical abdominal surgical scar.

Personal Observation: A recent trauma in an 70 year old patient, followed by a sudden internal hemorrhage because of a penetration in abdomen of a bone stump, originated from a fracture of a not known heterotopic ossification of an old median abdominal scar, of a laparotomy of many years earlier for perforated duodenal ulcer.

Results: An emergency surgery was mandatory DISCUSSION: Pathogenesis of heterotopic ossification, as rare metaplastic phenomenon outside of the normal bone tissue, still unknown and speculative. Read More

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June 2018
17 Reads

A Tale of Two Eras: Mining Big Data from Electronic Health Records to Determine Limb Salvage Rates with Podiatry.

Curr Diabetes Rev 2018 Oct 16. Epub 2018 Oct 16.

Michigan Medicine, Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes. Domino's Farms (Lobby C, Suite 1300) 24 Frank Lloyd Wright Drive Ann Arbor, Michigan 48106. United States.

Aims/hypothesis: Diabetes foot complications remain very prevalent in US and worldwide, and a major risk for devastating amputations. We evaluated the impact of establishing a fully integrated and specialized Podiatry service into a large tertiary academic health system to implement structured and targeted preventative foot care on limb salvage rates.

Methods: Cross-sectional cohorts' data mining analysis of all encounters for diabetes and any foot complications between 2000-2005 and 2010-2015, preceding and after full implementation of podiatry service, respectively. Read More

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http://dx.doi.org/10.2174/1573399814666181017104818DOI Listing
October 2018
3 Reads

An electrochemically deposited collagen wound matrix combined with adipose-derived stem cells improves cutaneous wound healing in a mouse model of type 2 diabetes.

J Biomater Appl 2018 Oct;33(4):553-565

1 Southwest Research Institute, Department of Pharmaceuticals and Bioengineering, San Antonio, TX, USA.

Chronic wounds complicated by diabetes are a significant clinical issue, and their occurrence is expected to continue to rise due to an increased prevalence of diabetes mellitus, especially type 2 diabetes. Diabetic wounds frequently lead to nonhealing ulcers, and often eventually result in limb amputation due to the high risk of infection of the chronic wound. Here, we present a tissue-engineered treatment that combines a novel electrochemically deposited collagen wound matrix and human adipose-derived stem cells. Read More

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http://journals.sagepub.com/doi/10.1177/0885328218803754
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http://dx.doi.org/10.1177/0885328218803754DOI Listing
October 2018
3 Reads
2.200 Impact Factor

Diabetes Comorbidity Increases Risk of Postoperative Complications in Traumatic Thoracic Vertebral Fracture Repair: A Propensity Score Matched Analysis.

World Neurosurg 2019 Jan 9;121:e792-e797. Epub 2018 Oct 9.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Background: Thoracic vertebral fracture repair after a traumatic injury can be associated with significant risk for postoperative complications. Surgical outcomes are further complicated by patient comorbidity, particularly diabetes mellitus. This study compared outcomes and complication rates for traumatic thoracic vertebral fracture repair in a matched sample of patients with diabetes and nondiabetic control subjects. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183228
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http://dx.doi.org/10.1016/j.wneu.2018.09.225DOI Listing
January 2019
2 Reads
2.420 Impact Factor

Current concepts for the evaluation and management of diabetic foot ulcers.

EFORT Open Rev 2018 Sep 27;3(9):513-525. Epub 2018 Sep 27.

Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece.

The lifetime risk for diabetic patients to develop a diabetic foot ulcer (DFU) is 25%. In these patients, the risk of amputation is increased and the outcome deteriorates.More than 50% of non-traumatic lower-extremity amputations are related to DFU infections and 85% of all lower-extremity amputations in patients with diabetes are preceded by an ulcer; up to 70% of diabetic patients with a DFU-related amputation die within five years of their amputation. Read More

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https://online.boneandjoint.org.uk/doi/10.1302/2058-5241.3.1
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http://dx.doi.org/10.1302/2058-5241.3.180010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174858PMC
September 2018
31 Reads

Healthcare utilization following spinal cord injury: Objective findings from a regional hospital registry.

J Spinal Cord Med 2019 Mar 2;42(2):194-200. Epub 2018 Oct 2.

b Department of Trauma , Baylor University Medical Center , Dallas , Texas , USA.

Objective: The purpose was to describe the prevalence and characteristics of healthcare utilization among individuals with spinal cord injury (SCI) from a Level I trauma center.

Design: Retrospective data analysis utilizing a local acute trauma registry for initial hospitalization and merged with the Dallas-Fort Worth Hospital Council registry to obtain subsequent health care utilization in the first post-injury year.

Setting: Dallas, TX, USA. Read More

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https://www.tandfonline.com/doi/full/10.1080/10790268.2018.1
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http://dx.doi.org/10.1080/10790268.2018.1505330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419654PMC
March 2019
18 Reads

Risk factors of pelvic pressure ulcer recurrence after primary skin flap surgery in people with spinal cord injury.

Ann Phys Rehabil Med 2019 Mar 28;62(2):77-83. Epub 2018 Sep 28.

Centre mutualiste neurologique Propara, 263, rue du Caducée, 34090 Montpellier, France. Electronic address:

Background: Flap surgery for deep pelvic pressure ulcers (PPUs) has been found effective, but the recurrence rate remains high and few risk factors have been identified.

Objective: We evaluated risk factors for PU recurrence after primary flap surgery in people with spinal cord injury (SCI).

Patients And Methods: This observational retrospective study based on medical charts included all individuals with SCI who underwent primary flap surgery for a PPU in the Hérault department in France between 2006 and 2014. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18770657183144
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http://dx.doi.org/10.1016/j.rehab.2018.08.005DOI Listing
March 2019
20 Reads

PATTERN OF PRESENTATION OF ORAL ULCERATIONS IN PATIENTS ATTENDING AN ORAL MEDICINE CLINIC IN NIGERIA.

Ann Ib Postgrad Med 2018 Jun;16(1):9-11

Department of Oral and Maxillofacial Surgery and Oral Pathology, Obafemi Awolowo University Teaching Hospital Complex, Ile-Ife, Osun State, Nigeria.

Aim: This study aimed at describing the epidemiology and pattern of presentation of oral ulcerations among patients seen in Oral Medicine clinic of Obafemi Awolowo University Complex, Ile-Ife.

Methodology: This study was a retrospective cohort study of all cases that presented with oral ulcers in the oral medicine clinic between May 2015 and May 2017. The clinical diagnosis of oral ulcers was based on the WHO guidelines for oral mucosa diagnosis. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6143886PMC
June 2018
2 Reads

Polysaccharides from tubers of Bletilla striata: Physicochemical characterization, formulation of buccoadhesive wafers and preliminary study on treating oral ulcer.

Int J Biol Macromol 2019 Feb 15;122:1035-1045. Epub 2018 Sep 15.

Pharmacy College, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, PR China. Electronic address:

The purpose of this research is to arouse people's cognition of the dual role of Bletilla striata polysaccharide (BSP)-a kind of biocompatible, biodegradable natural biological materials with myriad pharmacological activities. BSP was extracted and characterized firstly. The results indicated that BSP was composed of mannose and glucose. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2018.09.050DOI Listing
February 2019
2 Reads

Ultrasonographic assessment of paediatric ocular emergencies: A tertiary eye hospital based observation.

World J Emerg Med 2018 ;9(4):272-275

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.

Background: The purpose of this study is to assess the utility of ocular ultrasound B scan in the emergency at the first point of care for detecting posterior segment and orbital pathologies in cases of paediatric ocular emergencies.

Methods: A prospective observational study involving 122 paediatric patients presenting to eye emergency over a period of ninety days were assessed with ultrasonography for the posterior segment as well as orbital pathology whenever indicated. The ocular ultrasound was performed gently over closed eyelids. Read More

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http://dx.doi.org/10.5847/wjem.j.1920-8642.2018.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117533PMC
January 2018
4 Reads