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    Human Recombinant Epidermal Growth Factor in skin lesions: 77 cases in EPItelizando Project.
    J Dermatolog Treat 2018 Apr 23:1-23. Epub 2018 Apr 23.
    a Centro Médico Teknon , Barcelona , Spain.
    Objective: To analyze compounded recombinant human Epidermal Growth Factor (rhEGF) effectiveness on skin lesions through a case series.

    Design: Multicentric series of skin lesions treated with topical recombinant human Epidermal Growth Factor. SITE: Patients from 56 different health professionals, three different countries, two recruitment years. Read More
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    Safety profile of chronic leg ulcer biopsy: a monocentric retrospective series on 866 patients.
    G Ital Dermatol Venereol 2018 Apr 19. Epub 2018 Apr 19.
    Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.
    Background: Skin biopsy is an important tool for various skin conditions. However, in the case of leg ulcers, some Authors still consider it highly risky and mandatory only in selected cases.

    Methods: To evaluate the rate of adverse events after leg ulcers biopsy in 866 consecutive patients referring to our Wound Care Unit in Bologna from January 2008 to December 2016. Read More
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    Comparison of Wound Tape and Suture Wounds on Traumatic Wounds' Scar.
    Adv Biomed Res 2018 27;7:49. Epub 2018 Mar 27.
    Emergency Medicine Research Center, Al-Zahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
    Background: Several methods have been used in wound closure for traumatic wounds, but it is not clear that which of these methods has more safety and efficacy. This study aimed to compare scar width due to standard and current treatments in wound repair by suturing and method of wound restoration using wound tape in patients with traumatic ulcers.

    Materials And Methods: This randomized clinical trial was done in ninety patients with wounds in the facial area. Read More
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    Expression of vascular endothelial growth factor and matrix metalloproteinase-9 in Lawang propolis extract gel-treated traumatic ulcers in diabetic rats.
    Vet World 2018 Mar 14;11(3):304-309. Epub 2018 Mar 14.
    Department of Oral Medicine, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia.
    Aim: The aim of this study was to determine the effect of propolis extract gel on vascular endothelial growth factor (VEGF) and matrix metalloproteinase-9 (MMP-9) expression in the traumatic ulcers of rats afflicted with diabetes mellitus (DM).

    Materials And Methods: The study was conducted on 24 male Wistar rats () induced with DM by injecting 50 mg/kg of Streptozotocin, intraperitoneally, and a traumatic ulcer on their lower lip mucosa. These were divided into eight groups: Four each for control and treatment groups. Read More
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    Nursing Sensitive Outcomes After Severe Traumatic Brain Injury: A Nationwide Study.
    J Neurosci Nurs 2018 Apr 12. Epub 2018 Apr 12.
    Questions or comments about this article may be directed to Lene Odgaard, PhD MHS RN, at She is Data Manager, Hammel Neurorehabilitation Centre and University Research Clinic, Hammel, Denmark. Lena Aadal, PhD MSN RN, is Head of Clinical Nursing Research, Hammel Neurorehabilitation Centre and University Research Clinic, Hammel, Denmark. Marianne Eskildsen, is Social and Health Assistant, Department of Neurorehabilitation, Traumatic Brain Injury, Rigshospitalet, Copenhagen University Hospital, Hvidovre, Denmark. Ingrid Poulsen, PhD RN, is Associate Professor and Research Manager, RUBRIC (Research Unit on Brain Injury Rehabilitation), Department of Neurorehabilitation, Traumatic Brain Injury, Rigshospitalet, Copenhagen University Hospital, Hvidovre; and Section of Nursing Science, Aarhus University, Aarhus, Denmark.
    Background: Complications such as infections and conditions after immobilization are frequent after severe traumatic brain injury (TBI) due to compromised bodily functions. Traditionally, bodily functions are core elements in nursing, and therefore nurses in the rehabilitation departments are pivotal in the prevention of complications. Hence, the frequency of complications is an indicator of nursing care quality, which can be included in nursing-sensitive outcome indicators. Read More
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    Neuroprotective Effects of Platonin, a Therapeutic Immunomodulating Medicine, on Traumatic Brain Injury in Mice after Controlled Cortical Impact.
    Int J Mol Sci 2018 Apr 6;19(4). Epub 2018 Apr 6.
    Department of Pharmacology, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
    Traumatic brain injury (TBI) is one of the leading causes of mortality worldwide and leads to persistent cognitive, sensory, motor dysfunction, and emotional disorders. TBI-caused primary injury results in structural damage to brain tissues. Following the primary injury, secondary injuries which are accompanied by neuroinflammation, microglial activation, and additional cell death subsequently occur. Read More
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    Delayed Splenic Rupture Resulting in Massive Intraperitoneal Hemorrhage Post Ambulatory-Related Injury.
    Cureus 2018 Feb 5;10(2):e2160. Epub 2018 Feb 5.
    College of Medicine, Texas A&M College of Medicine.
    Delayed splenic rupture, once thought to be unusual, but now growing in incidence, is an issue that could potentiate severe morbidity and mortality to patients, regardless of the severity of the trauma. This case report presents one instance of delayed splenic rupture following minor trauma and discusses the need for further investigation in the management of this condition. A middle-aged, hypotensive male presented to the emergency department (ED) with signs of an acute abdomen following a syncopal episode, with successful resuscitation upon arrival. Read More
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    Use of Dehydrated Human Amnion/Chorion Membrane Allografts in More Than 100 Patients with Six Major Types of Refractory Nonhealing Wounds.
    J Am Podiatr Med Assoc 2018 Mar;108(2):84-89
    Background: Biochemical properties of the amniotic membrane help modulate inflammation and enhance soft-tissue healing. In controlled trials, the efficacy of dehydrated human amnion/chorion membrane (dHACM) allografts has been established. Our purpose is to describe our experience with using dHACM to treat nonhealing wounds of various etiologies. Read More
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    A functional polymorphism at miR‑491‑5p binding site in the 3'UTR of MMP9 gene confers increased risk for pressure ulcers after hip fracture.
    Oncol Rep 2018 Mar 28. Epub 2018 Mar 28.
    Department of Traumatic Ankle Surgery, Tianjin Hospital, Tianjin 300211, P.R. China.
    The roles of matrix metalloproteinase (MMP)9 in the control of pressure ulcers (PU) after hip fracture as well as how the rs1056629 in MMP9 3'UTR compromises the interaction between MMP9 and miR‑491 were explored. Online miRNA database (http://www.bioguo. Read More
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    Utilization of a Viable Human Amnion Membrane Allograft in Elderly Patients With Chronic Lower Extremity Wounds of Various Etiologies.
    Wounds 2018 Mar;30(3):E36-E40
    Medical Director, Wound Care Institute of Ocean County, Toms River, NJ; and Partner, Ocean County Foot and Ankle Surgical Associates, Toms River, NJ.
    ntroduction. Chronic nonhealing wounds are a growing health care problem in the United States, afflicting more than 6.5 million patients annually. Read More
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    Effect of a New Purified Collagen Matrix With Polyhexamethylene Biguanide on Recalcitrant Wounds of Various Etiologies: A Case Series.
    Wounds 2018 Mar;30(3):72-78
    Wayne UNC Health Care's Wound Healing and Hyperbaric Center, Goldsboro, NC.
    Introduction: The management of chronic, nonhealing wounds in patients with multiple comorbidities continues to be a challenge for health care practitioners. Chronic wounds typically do not progress through the normal phases of wound healing and generally remain stagnant during the inflammatory phase, resulting in an increase in proteolytic enzymes with degradation of the extracellular matrix. Bacterial biofilm has been documented to be one of the main factors delaying wound healing, resulting in the prolongation of the inflammatory phase. Read More
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    [Aortic diseases : Modern diagnostic and therapeutic strategies].
    Herz 2018 Mar 22. Epub 2018 Mar 22.
    Institut für Medizinische Informatik, Biometrie und Epidemiologie, Universitätsklinikum Essen, Universität Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Deutschland.
    Aortic diseases include not only the thoracic but also the abdominal part of the aorta. In the etiology cardiovascular risk factors, such as hypertension, smoking and hyperlipoproteinemia play a major role, but more and more genetic diseases with familiar predisposition are being identified. Even large aneurysms remain asymptomatic as long as other organs in the neighborhood are not damaged and no acute aortic event occurs including aortic dissection, intramural hematoma, penetrating aortic ulcer, and traumatic aortic injury. Read More
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    Cango Lyec (Healing the Elephant): Gender differences in HIV infection in post-conflict Northern Uganda.
    J Acquir Immune Defic Syndr 2018 Mar 2. Epub 2018 Mar 2.
    School of Population and Public Health, University of British Columbia, Vancouver, Canada.
    Background: As previously encamped resettle, potential for rapid HIV transmission in post-conflict Northern Uganda is concerning. Women in particular may be experiencing heightened vulnerability resulting from war-related sexual violence.

    Setting: Cango Lyec (Healing the Elephant) Project is a cohort involving conflict-affected people in three districts in Northern Uganda. Read More
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    Endoscopic Treatment of Benign Esophageal Fistulas Using Fully-covered Metallic Esophageal Stents.
    Chirurgia (Bucur) 2018 Jan-Feb;113(1):108-115
    Non-malignant esophageal fistulas have a wide spectrum of clinical and pathological features and it`s important to learn to detect and treat them, due to significant morbidity, mortality and costs. The need for minimally invasive, efficient and also quick procedures is imperative. Esophageal stenting using fully-covered expandable stents has become an increasingly preferred option and addresses to fistulas which arise from 2-3 cm beyond Killian's mouth and up to the gastroesophageal junction. Read More
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    Acute non-traumatic disease of the abdominal aorta.
    Abdom Radiol (NY) 2018 May;43(5):1067-1083
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S. Kingshighway Blvd, Campus Box 8131, St. Louis, MO, 63110, USA.
    Acute pathology in the abdominal aorta is associated with significant morbidity and mortality. The most feared complication of abdominal aortic disease is acute rupture in the setting of atherosclerotic abdominal aortic aneurysm. Although frank rupture often is easily diagnosed on CT, other findings such as a hyperattenuating crescent, discontinuous intimal calcium, and draping of the aorta are subtle signs of aneurysm instability. Read More
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    Follicular Unit Grafting in Chronic Nonhealing Leg Ulcers: A Clinical Study.
    J Cutan Aesthet Surg 2017 Oct-Dec;10(4):200-206
    Department of Dermatology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
    Introduction And Objectives: The restoration of the epithelium after injury takes place by migration of epithelial cells adjoining a wound or by centrifugal migration from hair follicles. To evaluate the feasibility and potential healing capacity of scalp follicular unit grafts transplanted into the wound bed of chronic leg ulcers.

    Materials And Methods: Patients with chronic nonhealing ulcers of more than 6 weeks duration were selected for the study. Read More
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    CAD/CAM produces dentures with improved fit.
    Clin Oral Investig 2018 Feb 22. Epub 2018 Feb 22.
    University Hospital for Dental Prosthetics and Restorative Dentistry, Medical University of Innsbruck, MZA, Anichstr. 35, A-6020, Innsbruck, Austria.
    Objectives: Resin polymerisation shrinkage reduces the congruence of the denture base with denture-bearing tissues and thereby decreases the retention of conventionally fabricated dentures. CAD/CAM denture manufacturing is a subtractive process, and polymerisation shrinkage is not an issue anymore. Therefore, CAD/CAM dentures are assumed to show a higher denture base congruence than conventionally fabricated dentures. Read More
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    Predictive Value of Braden Risk Factors in Pressure Ulcers of Outpatients With Spinal Cord Injury.
    Acta Med Iran 2018 Jan;56(1):56-61
    Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. AND Department of Neurosurgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
    Pressure Ulcers (PUs) remain among the most common complications after traumatic spinal cord Injuries (SCIs). The main goal of risk factor assessment with different tools has been to provisionally estimate the chance of developing pressure ulcers in patients with Spinal Cord Injury (SCI). Braden tool has been of good predictive value and most commonly employed in hospital communities for risk assessment of pressure sore development. Read More
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    Micrografting chronic lower extremity ulcers with mechanically disaggregated skin using a micrograft preparation system.
    J Wound Care 2018 Feb;27(2):60-65
    Vascular Surgeon, Clinica N. Annunziatella - Rome, Italy.
    Objective: The Rigenera system is a new standardised micrograft preparation system. It works by means of automated mechanical disaggregation of small tissue samples, extracting only the smallest cells (<50µm). The aim of this study was to retrospectively evaluate patients affected by chronic ulcers and who were treated with the micrograft preparation method. Read More
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    A profile of traumatic spinal cord injury and medical complications in Latvia.
    Spinal Cord Ser Cases 2017 6;3:17088. Epub 2017 Dec 6.
    2Riga Stradins University, Riga, Latvia.
    Study Design: A single centre retrospective study.

    Objectives: To collect data and analyse the epidemiological profile of traumatic spinal cord injury and its medical complications during the subacute rehabilitation period.

    Setting: Spinal Cord Injury Rehabilitation Programme of the National Rehabilitation Centre, 'Vaivari', Jurmala, Latvia. Read More
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    Imaging of non-neoplastic duodenal diseases. A pictorial review with emphasis on MDCT.
    Insights Imaging 2018 Apr 31;9(2):121-135. Epub 2018 Jan 31.
    Department of Diagnostic Imaging Institute (IDI) and Girona Biomedical Research Institute (IDIBGI), Dr. Josep Trueta University Hospital, Av/ Francia s/n, Girona, Spain.
    A wide spectrum of abnormalities can affect the duodenum, ranging from congenital anomalies to traumatic and inflammatory entities. The location of the duodenum and its close relationship with other organs make it easy to miss or misinterpret duodenal abnormalities on cross-sectional imaging. Endoscopy has largely supplanted fluoroscopy for the assessment of the duodenal lumen. Read More
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    Outcome analyses of a multimodal treatment approach for deep pressure ulcers in spinal cord injuries: a retrospective cohort study.
    Spinal Cord 2018 Jan 31. Epub 2018 Jan 31.
    Treatment Centre for Spinal Cord Injuries, Trauma Hospital Berlin, Berlin, Germany.
    Study Design: Retrospective observational cohort study.

    Objectives: To describe outcomes, risk factors for complications, and relapse rates associated with the multimodal treatment approach for deep pressure ulcers (PUs) grade IV for the ischium, trochanter major, and sacral regions of patients with traumatic and non-traumatic spinal cord injury (SCI).

    Setting: The settings comprised two spinal cord units within a maximum care hospital. Read More
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    Acute duodenal intramural hematoma complicated by acute pancreatitis-a rare complication of endoscopic epinephrine injection therapy.
    Oxf Med Case Reports 2018 Jan 23;2018(1):omx090. Epub 2018 Jan 23.
    Department of Internal Medicine, SBH Health System, Bronx, NY 10457,USA.
    Intramural duodenal hematoma (IDH) is a rare complication in endoscopic management of ulcer hemorrhage. Usually noted in cases of blunt abdominal trauma, non-traumatic IDHs have been reported in individuals on anticoagulation, with blood disorders, pancreatic diseases and in endoscopic procedures such as biopsy, sclerotherapy and argon plasma coagulation. Patients may be asymptomatic or present with acute blood loss anemia, abdominal pain or vomiting. Read More
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    Topical chlorhexidine, povidone-iodine and erythromycin in the repair of traumatic ulcers on the rat tongue: Clinical, histological and microbiological evaluation.
    Arch Oral Biol 2018 Mar 4;87:218-225. Epub 2018 Jan 4.
    Oral Medicine Division, Pontifical Catholic University of Rio Grande do Sul-PUCRS, Porto Alegre, RS, Brazil.
    Objective: This study investigated the effect of topical application of 0.12% chlorhexidine, 10% povidone-iodine and 50% erythromycin on the optimization of healing process of traumatic ulcers made on ventral tongue of rats.

    Design: Forty-Eight Wistar rats were randomly divided into four groups: control, chlorhexidine (Chx), povidone-iodine (PvI) and erythromycin (Er). Read More
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    Prevention of pressure ulcers in patients undergoing subacute rehabilitation after severe brain injury: An observational study.
    J Clin Nurs 2018 Jan 9. Epub 2018 Jan 9.
    Department of Neurorehabilitation, Traumatic Brain Injury, Rigshospitalet, Hvidovre, Denmark.
    Aims And Objectives: To uncover efforts made by healthcare professionals to prevent pressure ulcers in patients with severe brain injury undergoing treatment at a subacute rehabilitation department.

    Background: Pressure ulcers are a major burden for patients and also generate considerable healthcare costs. Pressure ulcers are, nevertheless, prevalent in both secondary care and primary care. Read More
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    First Aid for Skin Tears by Mini Patch Grafting from the Flap Edge.
    J Emerg Med 2018 Jan 3. Epub 2018 Jan 3.
    Department of Dermatology and Plastic Surgery, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
    Background: Traumatic skin tears often occur in patients with dystrophic skin. Closing them with adhesive skin closures is useful for patients with a healthy flap, but occasionally fails to cover the entire defect. We describe a simple technique to perform mini patch grafting on the remaining raw surface without damaging healthy skin. Read More
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    An Economic Evaluation of the Impact, Cost, and Medicare Policy Implications of Chronic Nonhealing Wounds.
    Value Health 2018 01 19;21(1):27-32. Epub 2017 Sep 19.
    Integra Lifesciences, Plainsboro, NJ, USA.
    Objective: The aim of this study was to determine the cost of chronic wound care for Medicare beneficiaries in aggregate, by wound type and by setting.

    Methods: This retrospective analysis of the Medicare 5% Limited Data Set for calendar year 2014 included beneficiaries who experienced episodes of care for one or more of the following: arterial ulcers, chronic ulcers, diabetic foot ulcers, diabetic infections, pressure ulcers, skin disorders, skin infections, surgical wounds, surgical infections, traumatic wounds, venous ulcers, or venous infections. The main outcomes were the prevalence of each wound type, Medicare expenditure for each wound type and aggregate, and expenditure by type of service. Read More
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    Epidemiology and Clinical Management of Traumatic Spine Injuries at a Major Government Hospital in Cambodia.
    Asian Spine J 2017 Dec 7;11(6):908-916. Epub 2017 Dec 7.
    Department of Neurosurgery, Preah Kossamak Hospital, Phnom Penh, Cambodia.
    Study Design: Cross sectional study.

    Purpose: To characterize the pattern of injury, describe the current clinical management, and determine the outcomes in traumatic spine injury (TSI) patients presenting to a major government hospital in Phnom Penh, Cambodia.

    Overview Of Literature: There is a paucity of literature on epidemiology or current clinical practices for TSIs in Cambodia. Read More
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    Self-Efficacy and Pressure Ulcer Prevention After Spinal Cord Injury-Results From a Nationwide Community Survey in Switzerland (SwiSCI).
    PM R 2017 Dec 7. Epub 2017 Dec 7.
    REHAB Basel, Clinic for Neurorehabilitation and Paraplegiology, Basel, Switzerland.
    Background: Pressure ulcers (PUs) are a common and severe health condition in persons with spinal cord injury (SCI). Skin-care strategies for PU prevention are usually provided during the first rehabilitation session. However, individuals with SCI often do not perform these strategies continuously, especially after discharge. Read More
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    Reduction of hyperthermia in pediatric patients with severe traumatic brain injury: a quality improvement initiative.
    J Neurosurg Pediatr 2018 Feb 1;21(2):164-170. Epub 2017 Dec 1.
    Division of Critical Care and.
    OBJECTIVE Severe traumatic brain injury remains a leading cause of morbidity and mortality in the pediatric population. Providers focus on reducing secondary brain injury by avoiding hypoxemia, avoiding hypotension, providing normoventilation, treating intracranial hypertension, and reducing cerebral metabolic demand. Hyperthermia is frequently present in patients with severe traumatic brain injury, contributes to cerebral metabolic demand, and is associated with prolonged hospital admission as well as impaired neurological outcome. Read More
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    Final diagnosis of 86 cases included in differential diagnosis of American tegumentary leishmaniasis in a Brazilian sample: a retrospective cross-sectional study.
    An Bras Dermatol 2017 Sep-Oct;92(5):642-648
    Division of Dermatology, Department of Medical Clinics, Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FMRP-USP) - Ribeirão Preto (SP), Brazil.
    Background: Cutaneous leishmaniasis is distributed worldwide, including Brazil. Its several clinical forms need to be distinguished from other dermatoses. Clinical similarities and lack of a gold standard diagnostic tool make leishmaniasis-like lesions a challenging diagnosis. Read More
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    Impact of Complete Spinal Cord Injury on Healing of Skin Ulcers in Mouse Models.
    J Neurotrauma 2018 Mar 11;35(6):815-824. Epub 2018 Jan 11.
    1 Department of Biomedical Engineering, Rutgers, The State University of New Jersey , Piscataway, New Jersey.
    Pressure ulcers (PUs) are common debilitating complications of traumatic spinal cord injury (SCI) and tend to occur in soft tissues around bony prominences. There is, however, little known about the impact of SCI on skin wound healing because of the lack of suitable animal models for studies in controlled experimental settings. Herein, we describe a reproducible and clinically relevant mouse model of PUs in the context of complete SCI. Read More
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    The Traumatic Tube: Bleeding Rectal Ulcer Caused by Flexi-Seal Device.
    Case Rep Gastrointest Med 2017 4;2017:5278971. Epub 2017 Oct 4.
    Department of Gastroenterology, University of Toledo Medical Center, Toledo, OH, USA.
    Diarrhea and fecal incontinence are common in critically ill patients and present a challenging problem in patient management. The Flexi-Seal® Fecal Management System is a device to divert the stools away from the patient, thus improving the care to patients with fecal incontinence. There have been only few case reports describing the complications with the use of this device. Read More
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    Treatment Outcomes for Isolated Maxillary Complex Fractures with Maxillomandibular Screws.
    Craniomaxillofac Trauma Reconstr 2017 Dec 12;10(4):278-280. Epub 2017 Apr 12.
    Department of Dental Surgery, Christian Medical College and Hospital Vellore, Vellore, Tamil Nadu, India.
    Intermaxillary fixation (IMF) is a basic and fundamental principle in the management of patients with fractures of the maxillomandibular complex. There are several shortcomings related to the conventionally recommended tooth-mounted devices that are used to achieve IMF. To circumvent these, the use of bone-borne screws has been advocated. Read More
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    The use of regression tree analysis for predicting the functional outcome following traumatic spinal cord injury.
    J Neurotrauma 2017 Oct 25. Epub 2017 Oct 25.
    CHU Sainte-Justine, Orthopedic Surgery, Montreal, Quebec, Canada.
    Predicting the long-term functional outcome following traumatic spinal cord injury is needed to adapt medical strategies and to plan an optimized rehabilitation. This study investigates the use of regression tree for the development of predictive models based on acute clinical and demographic predictors. This prospective study was performed on 172 patients hospitalized following traumatic spinal cord injury. Read More
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    Nutritional blood parameters and nutritional risk screening in patients with spinal cord injury and deep pressure ulcer-a retrospective chart analysis.
    Spinal Cord 2018 02 23;56(2):168-175. Epub 2017 Oct 23.
    Swiss Paraplegic Centre, Nottwil, Switzerland.
    Study Design: Retrospective chart review.

    Objectives: To describe (i) the nutritional blood parameters (NBP) and the nutritional risk screening (NRS) in patients with spinal cord injury (SCI) and pressure ulcers (PU) III and IV according to the EPUAP classification, and (ii) the relationship between both NBP and NRS.

    Setting: SCI acute care and rehabilitation clinic in Switzerland. Read More
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    Acute Management of Traumatic Brain Injury.
    Surg Clin North Am 2017 Oct;97(5):1015-1030
    Division of Trauma, Surgical Critical Care, and Emergency General Surgery, Department of Surgery, Section of Surgical Sciences, Center for Health Services Research, Vanderbilt Brain Institute, Vanderbilt University Medical Center, 1211 21st Avenue South, Medical Arts Building, Suite 404, Nashville, TN 37212, USA; Surgical Services, Nashville Veterans Affairs Medical Center, Tennessee Valley Healthcare System, 1310 24th Avenue South, Nashville, TN 37212, USA. Electronic address:
    Traumatic brain injury (TBI) is a leading cause of death and disability in patients with trauma. Management strategies must focus on preventing secondary injury by avoiding hypotension and hypoxia and maintaining appropriate cerebral perfusion pressure (CPP), which is a surrogate for cerebral blood flow. CPP can be maintained by increasing mean arterial pressure, decreasing intracranial pressure, or both. Read More
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    Infection of recurrent calcaneal ulcer caused by a biofilm-producer Myroides odoratimimus strain.
    Folia Microbiol (Praha) 2018 Mar 27;63(2):203-207. Epub 2017 Sep 27.
    Department of Medical, Oral, and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via Vestini 31, 66100, Chieti, Italy.
    We report a case of recurrent post-traumatic ulcer infection due to Myroides odoratimimus in an immunocompromised male. We have also reviewed the medical literature on isolated M. odoratimimus infections. Read More
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    Eosinophilic ulcer of the tongue masquerading as malignant ulcer: An unexplored distinct pathology.
    J Oral Maxillofac Pathol 2017 May-Aug;21(2):321
    Department of Oral Pathology and Microbiology, Saraswati Dental College, Lucknow, Uttar Pradesh, India.
    Eosinophilic ulcer (EU) is a rare self-limiting chronic benign ulcerative lesion of the oral mucosa often misdiagnosed as oral malignancy. Its etiopathogenesis is ambiguous, but trauma plays an important role in the development. Microscopically, it is characterized by a polymorphic inflammatory infiltrate with a prominent eosinophilic component and large mononuclear cells extending deep into the submucosa, underlying muscle and salivary glands. Read More
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    Development of Acute Promyelocytic Leukemia in a Patient with Tetraplegia While in Inpatient Rehabilitation: a Case Report.
    J Spinal Cord Med 2017 Sep 20:1-4. Epub 2017 Sep 20.
    a Spinal Cord Injury Service and Disorders ; Hunter Holmes McGuire VA Medical Center , Richmond , VA , USA.
    Study Design: a single case report.

    Objectives: To report a case of a patient with tetraplegia who developed acute promyelocytic leukemia (APL) while in inpatient rehabilitation after 10.5 months. Read More
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    Predictors of pressure ulcer incidence following traumatic spinal cord injury: a secondary analysis of a prospective longitudinal study.
    Spinal Cord 2018 01 12;56(1):28-34. Epub 2017 Sep 12.
    Department of Occupational Therapy, UT Health Science Center, San Antonio, TX, USA.
    Study Design: Secondary analysis of data from a prospective cohort study.

    Objectives: The objective of this study was to identify the medical and demographic factors associated with the development of pressure ulcers during acute-care hospitalization and inpatient rehabilitation following acute spinal cord injury.

    Setting: The study was carried out at acute hospitalization, inpatient rehabilitation and outpatient rehabilitation sites at a university medical center in the United States. Read More
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    SURGICAL BURDEN OF DISEASE AT A REGIONAL HOSPITAL IN SOUTH AFRICA.
    S Afr J Surg 2017 Sep;55(3):68-69
    1Department of General Surgery, Worcester Hospital, and Ukwanda Rural Clinical School, Stellenbosch University, Worcester.
    Background: There is limited published data describing the nature of surgical admissions at a regional level in the South African context. Worcester Hospital General Surgery has introduced an electronic online database to manage its surgical services. This study uses that database to evaluate the surgical burden of disease for the Cape Winelands East and Overberg districts of the Western Cape. Read More
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    Traumatic spinal cord injury in the north-east Tanzania - describing incidence, etiology and clinical outcomes retrospectively.
    Glob Health Action 2017 ;10(1):1355604
    a Department of Community Medicine and Rehabilitation, Physiotherapy , Umeå University , Umeå , Sweden.
    Background: Causes, magnitude and consequences of traumatic spinal cord injury depend largely on geography, infrastructure, socioeconomic and cultural activities of a given region. There is a scarcity of literature on profile of traumatic spinal cord injury to inform prevention and rehabilitation of this health condition in African rural settings, particularly Tanzania.

    Objective: To describe the incidence, etiology and clinical outcomes of traumatic spinal cord injury and issues related to retrospective study in underdeveloped setting. Read More
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    Rapid Source-Control Laparotomy: Is There a Mortality Benefit?
    Surg Infect (Larchmt) 2017 Oct 28;18(7):787-792. Epub 2017 Aug 28.
    1 Department of Surgery, Grand Strand Regional Medical Center , Myrtle Beach, South Carolina.
    Background: The purpose of this study was to determine the influence rapid source-control laparotomy (RSCL) has on the mortality rate in non-trauma patients with intra-abdominal infection. The hypothesis was that RSCL reduces deaths and hospital lengths of stay (LOS) in patients compared with definitive repair and primary fascial closure (PFC).

    Methods: The International Classification of Diseases-10 codes for sepsis, gastric and duodenal ulcer perforation or hemorrhage, incisional or ventral hernia with obstruction, intestinal volvulus, ileus with obstruction, diverticulitis with perforation or abscess, vascular disorder of intestine, non-traumatic intestinal perforation, peritoneal abscess, and unspecified peritonitis were used to query the 2015 National Surgical Quality Improvement Project (NSQIP) database for all patients treated with either RSCL or PFC. Read More
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    Palatal perforation and chemical ulcers of the tongue in a blind patient.
    Spec Care Dentist 2017 Sep 22;37(5):253-257. Epub 2017 Aug 22.
    Assistant Professor of Preventive Care Dentistry, Amazonas State University, Manaus-AM, Brazil.
    We report a unique case of a potassium aluminum sulfate oral dissolution leading to palatal chemical necrosis and extensive chemical ulcers on the tongue. The patient, a 47-year-old white, blind male, denied using cocaine or other illegal drugs that could cause such lesions. His self-medication started as a treatment for a traumatic ulcerative lesion on the hard palate. Read More
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    Hepatocyte growth factor (HGF) optimizes oral traumatic ulcer healing of mice by reducing inflammation.
    Cytokine 2017 11 19;99:275-280. Epub 2017 Aug 19.
    Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, China. Electronic address:
    Objective: To evaluate the influence of overexpression HGF on the healing of traumatic ulcer of oral mucosa of mice.

    Material And Methods: Mice were divided into two groups: wild type C57BL6(WT) and HGF high expression transgenic (HGF-Tg) mice. Traumatic ulcer of all mice were made by number 15 scalpel blade. Read More
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    Spinal cord injury during the second trimester of pregnancy.
    Spinal Cord Ser Cases 2017 10;3:17052. Epub 2017 Aug 10.
    Department of Physical Medicine and Rehabilitation King Fahad Medical City, Riyadh, Saudi Arabia.
    Introduction: Pregnancies in women with spinal cord injury (SCI) are at greater risk of morbidity and mortality. Although pregnancy after SCI is well elaborated in the literature, SCI occurring during pregnancy is rarely reported. Abrupt changes in the body physiology because of SCI and the resulting disability add a risk to maternal and fetal well-being. Read More
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    Immobilization of Growth Factors to Collagen Surfaces Using Pulsed Visible Light.
    Biomacromolecules 2017 Oct 1;18(10):3185-3196. Epub 2017 Sep 1.
    Byers Eye Institute at Stanford University School of Medicine , Palo Alto, California 94303, United States.
    In the treatment of traumatic injuries, burns, and ulcers of the eye, inadequate epithelial tissue healing remains a major challenge. Wound healing is a complex process involving the temporal and spatial interplay between cells and their extracellular milieu. It can be impaired by a variety of causes including infection, poor circulation, loss of critical cells, and/or proteins, and a deficiency in normal neural signaling (e. Read More
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