Exp Neurol 2020 06 25;328:113260. Epub 2020 Feb 25.
International Collaboration on Repair Discoveries (ICORD), University of British Columbia (UBC), Vancouver, British Columbia, Canada; Department of Medicine, Division of Physical Medicine and Rehabilitation, UBC, Vancouver, British Columbia, Canada. Electronic address:
Among the most devastating sequelae of spinal cord injury (SCI) are genitourinary and gastrointestinal dysfunctions. Post-ganglionic neurons in pelvic ganglia (PG) directly innervate and regulate the function of the lower urinary tract (LUT), bowel, and sexual organs. A better understanding of how SCI affects PG neurons is essential to develop therapeutic strategies for devastating gastrointestinal and genitourinary complications ensuing after injury. Read More