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Mil Med 2020 Mar 16. Epub 2020 Mar 16.

Naval Health Research Center, 140 Sylvester Road, San Diego, CA 92106-3521.

Introduction: Limited research has analyzed the full range of outpatient medication prescription activity following serious combat injury. The objectives of this study were to describe (1) outpatient medication prescriptions and refills during the first 12 months after serious combat injury, (2) longitudinal changes in medication prescriptions during the first-year postinjury, and (3) patient characteristics associated with outpatient prescriptions.

Materials And Methods: This was a retrospective analysis of existing health and pharmacy data for a random sample of U. Read More

Int J Urol 2020 Apr 19;27(4):276-288. Epub 2020 Feb 19.

Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan.

The present article is an abridged English translation of the Japanese clinical guidelines for the diagnosis and treatment of lower urinary tract dysfunction in patients with spinal cord injury updated as of July 2019. The patients are adult spinal cord injured patients with lower urinary tract dysfunction; special consideration of pediatric and elderly populations is presented separately. The target audience is healthcare providers who are engaged in the medical care of patients with spinal cord injury. Read More

Medicine (Baltimore) 2020 Feb;99(7):e19262

Department of Emergency Medicine, Ajou University School of Medicine, Suwon, Republic of Korea.

Rationale: A spontaneous rupture of the bladder diverticulum in an adult patient is extremely rare. The recommended treatment is surgery. However, some cases can be successfully treated with urinary catheterization, antibiotics, and/or percutaneous peritoneal drainage. Read More

Eur J Radiol Open 2020 28;7:100215. Epub 2020 Jan 28.

Department of Radiology and Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

The incidence rate of ovarian herniation in the inguinal canal is 3 %. Nevertheless, the herniation of ovary with uterus is extremely scarce. Most of these cases are accompanied with congenital genitourinary malformations such as Mayer-Rakitansky-Kuster-Hauser (MRKH) syndrome and Mullerian duct malformations. Read More

Am Surg 2019 Dec;85(12):1402-1404

Traumatic intraperitoneal bladder rupture (IBR) requires surgical repair. Traditionally performed laparotomy, experience with laparoscopic bladder repair (LBR) after blunt trauma is limited. Benefits of laparoscopy include decreased length of stay (LOS), less pain, early return to work, fewer adhesions, and lower risk of incisional hernia. Read More

Mol Immunol 2020 02 26;118:142-152. Epub 2019 Dec 26.

Department of Medicine, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address:

Antibody-mediated rejection (AbMR) adversely affects long-term graft survival in kidney transplantation. Currently, the diagnosis of AbMR requires a kidney biopsy, and detection of complement C4d deposition in the allograft is one of the diagnostic criteria. Complement activation also generates several soluble fragments which could potentially provide non-invasive biomarkers of the process. Read More

World J Emerg Surg 2019 2;14:54. Epub 2019 Dec 2.

Emergency and Trauma Surgery, Maggiore Hospital, Parma, Italy.

Renal and urogenital injuries occur in approximately 10-20% of abdominal trauma in adults and children. Optimal management should take into consideration the anatomic injury, the hemodynamic status, and the associated injuries. The management of urogenital trauma aims to restore homeostasis and normal physiology especially in pediatric patients where non-operative management is considered the gold standard. Read More

Ceska Gynekol 2019 ;84(4):289-292

Objective: The aim of this work is to present a case of traumatic bladder rupture in a patient with total uterine prolapse. Additionally, we provide a brief description of this issue.

Design: Case report. Read More

Urologiia 2019 Dec(5):109-111

Department of urology of FGBOU VO North-Western State Medical University named after I.I. Mechnikov, Saint Petersburg, Russia.

In case of stricture of the lower third of ureter in patients with duplex kidney, ureteroneocystostomy or transureteroureterostomy can be used. Anastomosis of the injured ureter of the upper pole with the pelvis of the lower pole is considered nontypical. In this clinical observation, a 46-year-old patient with iatrogenic trauma of the pelvic part of the upper pole of a duplex kidney successfully undergone laparoscopic ureteropyelostomy. Read More

Acta Cir Bras 2019 28;34(9):e201900901. Epub 2019 Nov 28.

Full Professor, Urogenital Research Unit, UERJ, Rio de Janeiro-RJ, Brazil. Critical revision, final approval.

Purpose: To evaluate the effects of tadalafil (TD) in preventing histological alterations of the corpus cavernosum caused by isolated lesions of cavernous nerve (ILCN) and artery (ILCA) in rats.

Methods: Fifty male Wistar rats were randomly assigned in five groups: G1: control; G2: bilateral ILCN; G3: bilateral ILCA; G4: ILCN+TD; G5: ILCA+TD. The cavernous bodies were submitted to histomorphometry, immunohistochemistry and biochemical analysis. Read More

Clin Lab 2019 Nov;65(11)

Background: This study investigated the association between urinary levels of interleukin (IL)-6, IL-10, and tumor necrosis factor-alpha (TNF-α) with estimated glomerular filtration rate (eGFR), urinary albumin/creatinine ratio (uACR), and urinary neutrophil gelatinase-associated lipocalin (uNGAL) in patients with type 2 diabetes (T2D).

Methods: Urinary concentrations of IL-6, IL-10, TNF-α, ACR, and NGAL were measured in 121 patients with T2D.

Results: Urinary IL-6 and TNF-α increased 45. Read More

N Engl J Med 2019 11;381(19):1876-1878

Johns Hopkins School of Medicine, Baltimore, MD.

Am J Pathol 2020 01 22;190(1):108-124. Epub 2019 Oct 22.

Division of Nephrology, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Division of Nephrology, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

Keratinocyte growth factor (KGF) improves cyclophosphamide-induced bladder injury. To understand the mechanisms, we subcutaneously administered KGF to mice 24 hours before i.p. Read More

J Urol 2020 04 24;203(4):779-785. Epub 2019 Oct 24.

Department of Urology, Graduate School of Medical Sciences, Fukuoka, Japan.

Purpose: We sought to identify the symptoms and noninvasive test parameters associated with detrusor underactivity and develop a prediction model of detrusor underactivity. We analyzed clinical data on male patients with lower urinary tract symptoms who underwent pressure-flow studies.

Materials And Methods: Included in analysis were 909 men who met study criteria and whose data included the International Prostate Symptom Score, free uroflowmetry, post-void residual urine volume and prostate volume. Read More

PLoS Negl Trop Dis 2019 10 23;13(10):e0007338. Epub 2019 Oct 23.

Centre for Snakebite Research & Interventions, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, Merseyside, United Kingdom.

Background: Daboia siamensis (Eastern Russell's viper) is a medically important snake species found widely distributed across Southeast Asia. Envenomings by this species can result in systemic coagulopathy, local tissue injury and/or renal failure. While administration of specific antivenom is an effective treatment for Russell's viper envenomings, the availability of, and access to, geographically-appropriate antivenom remains problematic in many rural areas. Read More

AJR Am J Roentgenol 2019 12 15;213(6):1297-1306. Epub 2019 Oct 15.

Department of Radiology, University of Michigan, Taubman Center B1, 1500 E Medical Center Dr, Ann Arbor, MI 48109.

Blunt pelvic trauma is associated with injuries to the musculoskeletal, lower genitourinary, and vascular systems, leading to significant morbidity and mortality. This article provides a comprehensive review of these injuries, reviews classification systems that are helpful in predicting prognosis, describes the most appropriate imaging tests for injury detection, and emphasizes the role that interventional radiology plays in the setting of pelvic trauma. Blunt pelvic injuries can involve the musculoskeletal, genitourinary, and vascular systems, often concomitantly, making it imperative for radiologists to recognize injury patterns and understand implications for management. Read More

Updates Surg 2019 Dec 19;71(4):735-740. Epub 2019 Sep 19.

Department of Surgery, University of California Irvine Medical Center, 333 City Bldg. West, Suite 1600, Orange, CA, 92868, USA.

Vaginal and vulvar trauma may occur accidentally or because of an act of violence. Due to its rarity, little is known about risk factors effecting need for operative intervention. We sought to perform a large descriptive analysis of adult non-obstetric vulvovaginal trauma (VVT) and elucidate risk factors for requiring operative intervention. Read More

Neurourol Urodyn 2019 11 18;38(8):2194-2199. Epub 2019 Sep 18.

Department of Urology, Nottingham City Hospital, Nottingham, UK.

Objectives: Limited data exist on the risks of complications associated with a suprapubic catheter (SPC) insertion. Bowel injury (BI) is a well-recognized albeit uncommon complication. Guidelines on the insertion of SPC have been developed by the British Association of Urological Surgeons, but there remains little evidence regarding the incidence of this complication. Read More

Int Urol Nephrol 2019 Dec 6;51(12):2137-2141. Epub 2019 Sep 6.

Urology Service, Hospital del Trabajador, Ramón Carnicer 185, Providencia, Santiago, Región Metropolitana Chile, Chile.

Introduction: To evaluate the impact of a modified transurethral resection of prostate (mTURP) in patients with a history of pelvic fracture urethral injury (PFUI) status post-urethroplasty, and subsequent lower urinary tract symptoms (LUTS) refractory to medical therapy caused by benign prostatic hyperplasia (BPH).

Methods: Five patients were identified with a history of PFUI and a successful reconstruction of the urethra, who developed severe LUTS. After maximal medical therapy failed, these patients underwent a mTURP. Read More

Am J Obstet Gynecol 2020 02 27;222(2):179.e1-179.e9. Epub 2019 Aug 27.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Nashville, TN.

Background: The incidence of placenta accreta spectrum is rising. Management is most commonly with cesarean hysterectomy. These deliveries often are complicated by massive hemorrhage, urinary tract injury, and admission to the intensive care unit. Read More

PLoS One 2019 29;14(8):e0221813. Epub 2019 Aug 29.

Department of Surgical and Perioperative Sciences, Anesthesiology and Intensive Care Medicine (Östersund), Umeå University, Umeå, Sweden.

Background: Heparin-binding protein (HBP) is released by neutrophils upon activation, and elevated plasma levels are seen in inflammatory states like sepsis, shock, cardiac arrest, and burns. However, little is known about the elimination of HBP. We wanted to study renal clearance of HBP in healthy individuals and in burn patients in intensive care units (ICUs). Read More

Transplant Proc 2019 Oct 19;51(8):2814-2822. Epub 2019 Aug 19.

Division of Nephrology, Department of Internal Medicine, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea. Electronic address:

Background: α-Antitrypsin (AAT) is an important protein in the anti-inflammatory response that functions to regulate the activity of serine proteinases. We aimed to evaluate the protective effect of AAT on ischemia-reperfusion injury (IRI) in a mouse model.

Methods: We investigated the effects of AAT in a C57BL/6 mouse model of IRI by dividing them into 4 groups: normal control, sham operated, ischemia-reperfusion (IR), and IR after AAT pretreatment (IR-AAT). Read More

Int J Radiat Oncol Biol Phys 2019 12 14;105(5):1025-1033. Epub 2019 Aug 14.

Department of Radiation Oncology, City of Hope National Medical Center, Duarte, California. Electronic address:

Purpose: Toxicities after organ sparing myeloablative total marrow irradiation (TMI) conditioning regimens have not been well characterized. The purpose of this study is to report pulmonary, renal, thyroid, and cataract toxicities from a prospective trial monitoring patients up to 8 years after TMI.

Methods And Materials: A total of 142 patients with primarily multiple myeloma or acute leukemia undergoing hematopoietic cell transplantation were evaluated. Read More

S Afr J Surg 2019 Sep;57(3):54

Department of Surgery, University of the Witwatersrand, Johannesburg, South Africa and Department of Surgery, University of KwaZulu-Natal, Durban, South Africa.

Background: Humans come into contact and interact with an array of animals in a number of areas and environments. We set out to review our experience with animal-related injuries in Pietermaritzburg, KwaZulu-Natal, South Africa.

Method: All patients who sustained an injury secondary to an interaction with an animal in the period December 2012-December 2017 were identified from the Hybrid Electronic Medical Registry (HEMR). Read More

Med Sci Monit 2019 Aug 7;25:5878-5885. Epub 2019 Aug 7.

Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong, China (mainland).

BACKGROUND Advances in percutaneous nephrolithotomy (PCNL) have resulted in smaller devices that cause less trauma and bleeding, while flexible ureterorenoscopy (f-URS) allows access to any calyces. These methods are often used in isolation, but used in combination they may improve treatment of complex renal calculi. This study assessed the effectiveness and complications of f-URS combined with super-mini-PCNL (SMP) to treat complex renal calculi. Read More

Biol Res 2019 Aug 6;52(1):41. Epub 2019 Aug 6.

School of Public Health, Beihua University, Jilin, 132013, China.

Background: Di-N-butyl-phthalate (DBP) is an endocrine disrupting substance. We investigated the adverse effect of DBP on testis of male rat and reveal its potential mechanism of MAPK signaling pathway involved this effect in vivo and in vitro. Gonadal hormone, sperm quality, morphological change and the activation status of JNK, ERK1/2 and p38 was determined in vivo. Read More

Surg Technol Int 2019 11;35:43-47

Department of Urology, University Hospital Munich-Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany.

Background: Utricular cysts are usually the result of incomplete involution of the Müllerian ducts and may have no urethral connection. Treatment options for symptomatic utricular cysts include an open abdominal approach, trans-vesical excision, vasoligation without excision and laparoscopic/robotic-assisted excision.

Patients And Methods: Two patients (14 and 45 years old) with recurrent urinary tract infections associated with recurrent lower urinary tract irritative symptoms and recurrent perineal pains presented to our department. Read More

J Surg Res 2019 12 19;244:477-483. Epub 2019 Jul 19.

Division of Trauma, Burns, & Surgical Critical Care, Daughtry Family Department of Surgery, University of Miami Miller School of Medicine and Ryder Trauma Center, Miami, Florida. Electronic address:

Background: Augmented renal clearance (ARC; i.e., creatinine clearance [CL] ≥ 130 mL/min) has an incidence of 14%-80% in critically ill patients and has been associated with therapy failures for renally cleared drugs. Read More

J Ovarian Res 2019 Jul 19;12(1):65. Epub 2019 Jul 19.

State Key Laboratory of Reproductive Medicine, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, 210029, People's Republic of China.

Background: Premature ovarian insufficiency (POI) is characterized by early loss of ovarian function that affects women before the age of 40. We aim to explore the protective effects of transcutaneous electrical acupoint stimulation (TEAS) against irradiation-induced ovarian damage in mice.

Methods: C57BL6 mice were randomly divided into control and irradiation (IR) groups. Read More

Obstet Gynecol 2019 08;134(2):333-342

Division of Urogynecology, the Division of Biomedical Statistics and Informatics, and the Department of Urology, Mayo Clinic, Rochester, Minnesota; the Clinical Pharmacology Division, Vanderbilt University, Vanderbilt, Tennessee; and the Department of Obstetrics and Gynecology, Case Western Reserve University, Cleveland, Ohio.

Objective: To compare the reoperation rates for recurrent stress urinary incontinence (SUI) after retropubic and transobturator sling procedures.

Methods: We conducted a retrospective cohort study of all women who underwent midurethral sling procedures at a single institution for primary SUI between 2002 and 2012. To minimize bias, women in the two groups were matched on age, body mass index, isolated compared with combined procedure, and preoperative diagnosis. Read More

Obstet Gynecol 2019 08;134(2):241-249

Stanford University School of Medicine, Stanford, and Santa Clara Valley Medical Center, San Jose, California.

Objective: To explore the rates and risk factors for sustaining a genitourinary injury during hysterectomy for benign indications.

Methods: In this population-based cohort study, all women who underwent hysterectomy for benign indications were identified from the Office of Statewide Health Planning and Development databases in California (2005-2011). Genitourinary injuries were further classified as identified at the time of hysterectomy, identified after the date of hysterectomy; or unidentified until a fistula developed. Read More

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2019 Jun;44(6):642-648

Department of Nephrology, Second Xiangya Hospital, Central South University, Changsha 410011, China.

Objective: To investigate the correlation of different types of urinary abnormalities or different proteinuria and hematuria with the pathological injury of kidney in IgA nephropathy with isolated hematuria and/or mild proteinuria.
 Methods: Patients with primary IgA nephropathy, isolated hematuria and/or mild proteinuria were enrolled in the Department of Nephrology, the Second Xiangya Hospital, Central South University from January 2013 to January 2018. According to the difference of red blood cell count in urinary sediment and quantitative of 24-hour urinary protein (24 h-UP) during renal biopsy, the patients were grouped in 3 ways: a simple hematuria group, a hematuria and proteinuria group, and a simple proteinuria group; a proteinuria I group, a proteinuria II group, and a proteinuria III group; a hematuria I group, a hematuria II group, and a hematuria III group. Read More

J Surg Res 2019 12 11;244:278-290. Epub 2019 Jul 11.

Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China; Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University, Chengdu, Sichuan, China. Electronic address:

Background: The advent of transvaginal natural orifice transluminal endoscopic surgery (transvaginal NOTES) aims to minimize surgical trauma and reduce recovery time.

Materials And Methods: Clinical trials comparing transvaginal NOTES and traditional laparoscopy were identified by searching EMBASE, MEDLINE, and Web of Science (from 2004 to March 2018). Major outcomes evaluated were risk of postoperative complications and secondary outcomes were pain on postoperative day (POD) 1, POD2, and POD3, time needed for full recovery, risk of intraoperative complications, the duration of surgery, and hospital stay. Read More

J Forensic Leg Med 2019 Aug 2;66:120-128. Epub 2019 Jul 2.

Utah State University Department of Psychology, 2810 Old Main Hill, Logan, UT, 84341, USA. Electronic address:

Purpose: A series of studies suggest that non-Hispanic White women have significantly more injuries than non-Hispanic Black women after sexual assault and consensual sexual intercourse. One explanation for this difference is that the degree of skin protection may vary as skin mechanics and skin pigmentation vary. The aim of the study was to determine the association among genital-anal injury, skin color, skin viscoelasticity and skin hydration in women following consensual sexual intercourse when controlling for age, smoking history, body mass index (BMI), sun exposure, and health status. Read More

Biomed Res Int 2019 4;2019:1576359. Epub 2019 Jun 4.

Ob&Gyn and Menopause Clinic, Zagreb, Croatia.

Vaginal birth trauma is the leading cause of stress urinary incontinence (SUI) in women. Also, the process of ageing and hormonal deprivation in postmenopause alters the metabolism of connective tissues and decreases collagen production leading to pelvic floor dysfunction. Noninvasive treatment is recommended as first-line management of urinary incontinence (UI) in women. Read More

Zhonghua Fu Chan Ke Za Zhi 2019 Jun;54(6):375-380

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

To investigate the relationship between the previous cesarean scar thickness, previous cesarean scar defect and the occurrence of uterine rupture for pregnancy women after previous cesarean section and to predict the occurrence of uterine rupture in the third trimester for pregnancy women after previous cesarean section by analyzing the lower uterine segment (LUS) situation or quantitatively measure LUS myometrium thickness. A total of 154 pregnant women who have a prior cesarean from January 2015 to March 2016 were selected, all of them regularly did the prenatal examination in the pregnancy period and finally gave birth in hospital. By the transvaginal sonograph, the LUS myometrium thickness (transverse and longitudinal thickness) and the size of the previous cesarean scar defect were measured in the first trimester, the LUS myometrium thickness (longitudinal thickness) and qualitatively analysis LUS condition were measured in the third trimester. Read More

Neurourol Urodyn 2019 08 18;38(6):1760-1766. Epub 2019 Jun 18.

Department of Urology, China Rehabilitation Research Centre, Rehabilitation School of Capital Medical University, Beijing, China.

Aim: The maximum urethral closure pressure (MUCPs) and functional urethral length (FUL) obtained with water-filled and air-charged catheters during urethral pressure profile (UPP) determination was compared in a single, blind, randomized, and prospective trial.

Methods: Thirty-three males with spinal cord injuries and neurogenic lower urinary tract dysfunction underwent UPP determinations using water-filled and air-charged catheters in random order; the patients were unaware of the catheter sequence. The variability of the same type of catheter and the agreement between the different types of catheters were compared. Read More

J Trauma Acute Care Surg 2019 10;87(4):892-897

From the Department of Urology (X.P., H.G., X.Z., J.W.), Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Eastern Institute for Urologic Anastomosis and Reconstruction, Shanghai, China; and Department of Urology (X.P., H.G.), Children's Hospital of Shanghai, Shanghai Jiao Tong University, Shanghai, China.

Background: Cystostomy, endoscopic realignment, and emergency anastomosis are three methods used to treat bulbous urethral injury (BUI). The aim of the study is to determine the optimal management.

Methods: A retrospective study was performed on 328 male patients with blunt straddle injury to the perineum. Read More

Clinics (Sao Paulo) 2019 6;74:e787. Epub 2019 Jun 6.

Disciplina de Cirurgia Geral e Trauma, Departamento de Cirurgia, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Objectives: Intestinal obstruction has a high mortality rate when therapeutic treatment is delayed. Resuscitation in intestinal obstruction requires a large volume of fluid, and fluid combinations have been studied. Therefore, we evaluated the effects of hypertonic saline solution (HS) with pentoxifylline (PTX) on apoptosis, oxidative stress and survival rate. Read More

Int Braz J Urol 2019 Jul-Aug;45(4):754-762

Hospital Israelita Albert Einstein, São Paulo, Brasil.

Purpose: This study aimed to study morphological and renal structural changes in relation to different ischemic times and types of renal vascular pedicle clamping.

Methods: Sixteen pigs were divided into two groups (n = 8): Group AV - unilateral clamping of the renal artery and vein and Group A - unilateral clamping of the renal artery only, both with the contralateral kidney used as control. Serial biopsies were performed at 0, 10, 20, 30, 40, 50, 60, 70, 80, and 90 minutes after clamping. Read More

Z Geburtshilfe Neonatol 2019 Dec 4;223(6):350-358. Epub 2019 Jun 4.

Abteilung für Geburtsmedizin, Universitätsfrauenklinik Leipzig, Leipzig.

Introduction: Lower uterine segment (LUS) thickness measurement is frequently used to select patients for trial of labor after a previous cesarean section (TOLAC). To date no significant benefit of LUS measurement has ever been proven, and no standard protocol or clear cut-off value exists. The aim of this study was to evaluate the benefit of LUS measurement in a daily routine setting. Read More

Eur J Drug Metab Pharmacokinet 2019 Dec;44(6):837-843

Department of Pharmacotherapy, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose, Tokyo, 204-8588, Japan.

Background And Objective: The effect of cancer cachexia on the pharmacokinetics of vancomycin remains unclear. We investigated whether the pharmacokinetics of vancomycin and the risk of kidney injury are altered with the development of cancer cachexia.

Methods: A retrospective analysis was conducted using therapeutic drug monitoring data obtained from 86 cancer patients who received vancomycin intravenously for infection. Read More

Fish Physiol Biochem 2019 Aug 29;45(4):1409-1417. Epub 2019 May 29.

Fishery Resource and Environmental Management Division, Biochemistry Laboratory, ICAR - Central Inland Fisheries Research Institute, Barrackpore, Kolkata, 700120, India.

Temperature plays an important role on reproductive physiology of vertebrates including mammals, fish, and birds. It has varying effects on fish reproduction depending on the species; higher temperatures favor the spring-spawning species, while lower temperatures stimulate reproduction in autumn spawners. To evaluate the impact of high temperature on the reproductive physiology of minnow Puntius sophore, we carried out expression analysis of selected genes associated with gamete quality (hsp60, hsp70, hsp90, hsf1, vtg), pleuripotency (sox2, oct4, nanog), and sex determination (dmrt1) in gonads (ovary and testis) of P. Read More

J Coll Physicians Surg Pak 2019 Jun;29(6):S70-S72

Department of Obstetrics and Gynaecology, Jeddah National Hospital, Jeddah, Saudi Arabia.

Pregnancy in rudimentary horn is extremely rare and usually terminates in rupture during first and second trimester of pregnancy. Diagnosis of rudimentary horn pregnancy and its rupture is difficult and can be missed in routine ultrasound scan; and in majority of cases, it is detected after rupture. It requires high index of suspicion. Read More

J Vasc Interv Radiol 2019 Aug 23;30(8):1293-1302. Epub 2019 May 23.

Department of Radiology, University of Wisconsin, 600 Highland Ave., Madison, WI 53024.

Purpose: To demonstrate the feasibility of Robotically Assisted Sonic Therapy (RAST)-a noninvasive and nonthermal focused ultrasound therapy based on histotripsy-for renal ablation in a live porcine model.

Materials And Methods: RAST ablations (n = 11) were performed in 7 female swine: 3 evaluated at 1 week (acute) and 4 evaluated at 4 weeks (chronic). Treatment groups were acute bilateral (3 swine, 6 ablations with immediate computed tomography [CT] and sacrifice); chronic single kidney (3 swine, 3 ablations; CT at day 0, week 1, and week 4 after treatment, followed by sacrifice); and chronic bilateral (1 swine, 2 ablations). Read More

Brachytherapy 2019 Jul - Aug;18(4):484-492. Epub 2019 May 6.

Translational Research Center for Medical Innovation, Foundation for Biomedical Research and Innovation, Kobe, Hyogo, Japan.

Purpose: The purpose of this study was to evaluate acute and late genitourinary (GU) toxicity and to elucidate factors associated with GU toxicity in patients with prostate cancer treated with permanent seed implantation (PI) enrolled in a nationwide prospective cohort study in Japan.

Methods And Materials: Of 2,354 patients enrolled in this study, GU toxicity was evaluated in 2,339 patients at 3, 12, 24, and 36 months after PI. To elucidate independent factors predictive of acute and late Common Terminology Criteria for Adverse Events Grade 2 or higher (Grade ≥2) GU toxicity, multivariate logistic regression analyses were carried out. Read More

Arch Esp Urol 2019 May;72(4):428-435

UGC de Urología. Hospital Universitario de Puerto Real. Puerto Real. Cádiz. España.

Objective: This paper describes our initial experience with laparoscopic ureteroneocystostomy in two patients with distal ureter lesions following gynaecological surgery (hysterectomy). Furthermore, we review the evidence on the incidence, prevention, and management of urinary tract injuries that occur during laparoscopic gynaecological surgery. METHOD: Two patients with iatrogenic lower ureteral injuries during hysterectomy leading to ureterovaginal fistula underwent laparoscopic ureteroneocystostomy with a psoas hitch. Read More

Chin J Traumatol 2019 Jun 17;22(3):138-141. Epub 2019 Apr 17.

Department of Orthopedics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Electronic address:

Purpose: Pelvic fractures are severe injuries and are often associated with multiple system injuries, exacerbating the overall outcome. In India, the incidence of pelvic fractures is on a rise due to suboptimal roads and traffics but related literature regarding the overall epidemiology of these injuries is scarce and scanty. Our aim was to study the epidemiology of patients admitted with pelvic fractures at a level 1 trauma centre in India. Read More

Neurochem Res 2019 Oct 30;44(10):2405-2412. Epub 2019 Apr 30.

Department of Pediatrics, University of Maryland School of Medicine, 655 W. Baltimore Street, BRB 13-019, Baltimore, MD, 21201, USA.

Neonatal hypoxia-ischemia (HI) is a common cause of brain injury in infants. Acute kidney injury frequently occurs after birth asphyxia and is associated with adverse outcome. Treatment with acetyl-L-carnitine (ALCAR) after HI protects brain and improves outcome. Read More

Burns 2019 05 26;45(3):671-681. Epub 2018 Oct 26.

Department of Anesthesiology, The University of Texas Medical Branch, Galveston, TX, USA; Shriners Hospital for Children, Galveston, TX, USA. Electronic address:

Oxandrolone is a synthetic oral non-aromatizable testosterone derivative. This drug has been used successfully for several decades to safely treat growth delays in various diseases including Turner's syndrome. Currently the use of oxandrolone is under clinical testing in children with burn injury; the available data indicate that the anabolic steroid increases net muscle protein balance, maintains lean body mass, and reduces intensive care unit stay. Read More