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Cochrane Database Syst Rev 2021 03 18;3:CD011424. Epub 2021 Mar 18.

Department of Reproductive Medicine and Gynecology, University Medical Center, Utrecht, Netherlands.

Background: Intentional endometrial injury is being proposed as a technique to improve the probability of pregnancy in women undergoing assisted reproductive technologies (ART) such as in vitro fertilisation (IVF). Endometrial injury is often performed by pipelle biopsy and is a common gynaecological procedure with established safety. However, it causes a moderate degree of discomfort/pain and requires an additional pelvic examination. Read More

Mil Med 2021 Feb 27. Epub 2021 Feb 27.

Department of Urology, University of Texas Health Science Center San Antonio, San Antonio, TX 78229, USA.

Objective: To improve urotrauma care by describing veterans' current demographics and needs assessment during transitional care to the Veteran Health Administration (VHA) system.

Methods: We utilized our previously identified cohorts obtained from the DoD Trauma Registry data for male service members injured in theater linked with VHA electronic health records. We included veterans who received care at VHA at least once from October 2001 through September 2011 for chart review. Read More

Zhonghua Shao Shang Za Zhi 2021 Feb;37(2):143-149

Department of Burns, Zhengzhou First People's Hospital, Zhengzhou 450004, China.

To explore the value of renal injury marker protein in early diagnosis of acute kidney injury (AKI) in burn patients with delayed resuscitation. The retrospective case-control research was conducted. Forty-three burn patients with delayed resuscitation (27 males and 16 females, with age of 18-75 (35±3) years)who were admitted to Zhengzhou First People's Hospital from May 2018 to May 2020 met the inclusion criteria. Read More

Reproduction 2021 03;161(3):319-331

Department of Sports Injuries, Faculty of Physical Education and Sports Sciences, Allameh Tabataba'i University, Tehran, Iran.

The existing evidence suggests that the human reproductive system may be potentially vulnerable to COVID-19 infection. However, little is known about the virus-host interaction of COVID-19 in sperm cells. We are the first to address the connection between changes in multiple seminal biomarkers and reproductive function in male patients recovering from COVID-19. Read More

Geroscience 2021 Feb 7;43(1):409-422. Epub 2021 Jan 7.

Harvard Center for Population and Development Studies, 9 Bow Street, Cambridge, MA, 02138, USA.

While there is evidence of morbidity compression in many countries, temporal patterns of non-communicable diseases (NCDs) in developing countries, such as India, are less clear. Age at onset of disease offers insights to understanding epidemiologic trends and is a key input for public health programs. Changes in age at onset and duration of major NCDs were estimated for 2004 (n = 38,044) and 2018 (n = 43,239) using health surveys from the India National Sample Survey (NSS). Read More

BMJ Case Rep 2020 Dec 22;13(12). Epub 2020 Dec 22.

Urology, All India Institute of Medical Sciences, New Delhi, Delhi, India.

A 52-year-old man presented with lower urinary tract symptoms and intermittent haematuria for the last 6 months. He had undergone totally extraperitoneal right inguinal hernia repair a decade ago. The ultrasonography and an X-ray of the pelvis suggested a large radio-opaque shadow in the bladder. Read More

BMJ Case Rep 2020 Dec 22;13(12). Epub 2020 Dec 22.

Surgery (Urology Section), Aga Khan University Hospital, Karachi, Pakistan

Malignant lymphomas of the prostate are very rare tumours and are generally not considered in the clinical or pathological diagnosis of prostatic enlargement. We report a case of a 56-year-old man who presented with long-standing history of low back pain and a 2-month history of voiding lower urinary tract symptoms. He denied any history of urinary retention, trauma, catheterisation or any constitutional symptoms. Read More

Mol Med Rep 2021 02 23;23(2). Epub 2020 Dec 23.

Department of Endocrinology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, Liaodong 116011, P.R. China.

Renal damage is a common and severe condition encountered in the clinic. Luteolin (Lut) exhibits anti‑inflammatory, anti‑fibrotic and anti‑apoptotic effects. Thus, the present study aimed to investigate the pharmacological effects of Lut on angiotensin II (AngII)‑induced renal damage in apolipoprotein E‑deficient (ApoE) mice. Read More

Urol Case Rep 2021 Jan 26;34:101500. Epub 2020 Nov 26.

Hurley Medical Center, Department of Trauma Services, Flint, MI, USA.

We highlight the case of a 12 year old male who presented after sustaining a gunshot injury to the scrotum resulting in testicular, prostatic, and urethral transection in addition to pelvic fracture, extra peritoneal bladder injury, and transmural injury to recto sigmoid and ileum. The patient underwent a left orchiectomy, primary repair of the bladder and urethra, placement of universal plate on superior pubic rami, and segmental rectosigmoid and ileum resection. These findings illustrate the collaborative efforts of trauma surgery and urology to treat complex lower genitourinary (GU) injuries and how the direct prioritization of surgical efforts provides acceptable outcomes. Read More

Can Urol Assoc J 2020 Oct;14(10):305-316

McMaster University, Hamilton, ON, Canada.

Urethral stricture is fundamentally a fibrosis of the urethral epithelial and associated corpus spongiosum, which in turn, causes obstruction of the urethral lumen. Patients with urethral stricture most commonly present with lower urinary tract symptoms, urinary retention or urinary tract infection but may also experience a broad spectrum of other signs and symptoms, including genitourinary pain, hematuria, abscess, ejaculatory dysfunction, or renal failure. When urethral stricture is initially suspected based on clinical assessment, cystoscopy is suggested as the modality that most accurately establishes the diagnosis. Read More

S Afr J Surg 2020 Sep;58(3):150-153

Department of Surgery, University of the Witwatersrand, Johannesburg, South Africa.

Background: Knife wounds are common and represent a major burden to the South African healthcare system. This study reviews trends in spectrum, management and outcome of these injuries at a single trauma centre in KwaZulu-Natal(KZN).

Method: The regional hybrid electronic registry (HEMR) was reviewed for the period January 2013 - December 2018, and all patients who suffered a knife-related assault were identified and reviewed. Read More

J Med Case Rep 2020 Nov 24;14(1):227. Epub 2020 Nov 24.

Department of Obstetrics and Gynecology, University of Gondar, Gondar, Ethiopia.

Introduction: Genitourinary tract trauma caused by ox horn injury in the presence of pelvic organ prolapse (POP) is an extremely rare phenomenon and associated with devastating morbidity.

Case Presentation: A 50-year-old multiparous postmenopausal woman from rural northwest Ethiopia presented with the primary complaint of urinary incontinence 6 days after she suffered ox horn injury to her prolapsed genitalia. She had stage 3 pelvic organ prolapse with the leading point being the cervix. Read More

PLoS One 2020 11;15(11):e0239321. Epub 2020 Nov 11.

Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America.

Background: Testicular germ cell tumor (TGCT) incidence has increased in recent decades along with the use and dose of diagnostic radiation. Here we examine the association between reported exposure to diagnostic radiation and TGCT risk.

Methods: We conducted a case-control study of men with and without TGCT recruited from hospital- and population-based settings. Read More

Am J Obstet Gynecol 2021 May 3;224(5):502.e1-502.e10. Epub 2020 Nov 3.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Background: Complex lower urinary tract injury resulting from hysterectomy is a rare but highly morbid complication. Although intraoperative recognition reduces the risk of serious sequelae, observational studies have shown that most complex lower urinary tract injuries are recognized in the postoperative period. To date, limited research exists describing the timing of diagnosis of complex lower urinary tract injury or risk factors associated with complex lower urinary tract injury diagnosed in the postoperative period. Read More

Sci Rep 2020 10 23;10(1):18152. Epub 2020 Oct 23.

Instituto de Ciencia y Tecnología de Los Alimentos (ICTA), Facultad de Ciencias Exactas, Físicas y Naturales, Universidad Nacional de Córdoba (UNC), X5000JJC, Córdoba, Argentina.

Environmental challenges are integrated in the inmunoneuroendocrine interplay, impacting the immune system of the challenged individuals, and potentially implying transgenerational effects on their offspring. This study addressed whether dietary supplementation with thymol can modulate the immune response of adult Japanese quail when simultaneously exposed to an inoculum of inactivated Salmonella Enteritidis and a chronic heat stress (CHS). We also evaluated whether the experienced situations by adults can affect the immune response of their undisturbed offspring. Read More

Am J Emerg Med 2020 Sep 10. Epub 2020 Sep 10.

University of Louisville, Department of Emergency Medicine, Louisville, KY, United States of America.

Background: The COVID-19 pandemic has altered behaviors in the general population, as well as processes in the healthcare industry. Patients may be afraid to pursue care in the emergency department (ED) due to perceived risk of infection. The objective of this study was to determine the impact of COVID-19 on ED metrics. Read More

Scand J Med Sci Sports 2021 Feb 23;31(2):473-479. Epub 2020 Oct 23.

Department of Physical and Sports Education, School of Sports Science, PROmoting FITness and Health through Physical Activity Research Group (PROFITH), Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.

Kidney transplant recipients are at risk of developing important adverse effects after transplantation. The objective of this study was to investigate the effects of a 10-week supervised resistance exercise-based intervention in kidney transplant recipients. Sixteen participants were randomized to a training (n = 8, 49. Read More

J Urol 2021 Mar 6;205(3):841-847. Epub 2020 Oct 6.

Division of Urology, Department of Surgery, University of Utah, Salt Lake City, Utah.

Purpose: The majority of high grade renal trauma can be managed conservatively. However, nephrectomy is still common for acute management. We hypothesized that when controlling for multiple injury severity measures, nephrectomy would be associated with increased mortality. Read More

Zhejiang Da Xue Xue Bao Yi Xue Ban 2020 Aug;49(4):439-446

Department of Hypertension, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.

Objective: To investigate the expression of transient receptor potential canonical channels (TRPCs) in the heart and kidney of rat model of obstructive sleep apnea hypopnea syndrome (OSAHS).

Methods: Eighteen male SD rats were randomly assigned to intermittent hypoxia (IH) group (=9 ) and control group (=9). In IH group, rats were placed in a chamber and exposed to intermittent hypoxia for 8h (10AM-6PM) daily. Read More

J Urol 2021 Jan 28;205(1):213-218. Epub 2020 Aug 28.

University of Southern California, Los Angeles, California.

Purpose: Neurogenic lower urinary tract dysfunction is a significant source of morbidity for individuals with spinal cord injury and is managed with a range of treatment options that differ in efficacy, tolerability and cost. The effect of insurance coverage on bladder management, symptoms and quality of life is not known. We hypothesized that private insurance is associated with fewer bladder symptoms and better quality of life. Read More

Medicine (Baltimore) 2020 Aug;99(34):e21831

Department of Gastroenterology and Hepatology.

Adoption of interventional endoscopic procedures is increasing with increasing prevalence of diseases. However, medical radiation exposure is concerning; therefore, radiation protection for medical staff is important. However, there is limited information on the usefulness of an additional lead shielding device during interventional endoscopic procedures. Read More

Sci Rep 2020 08 14;10(1):13846. Epub 2020 Aug 14.

Department of Nephrology, Ajou University School of Medicine, Suwon, Republic of Korea.

Few data are available regarding fracture risk in patients treated with glucocorticoids, including patients with kidney disease. A population-based retrospective cohort study was performed using Health Insurance Review and Assessment Service database, a South Korean nationwide cohort set. This study identified 44,702 patients with diagnosis code of kidney diseases who received a renal biopsy between January 1, 2012 and December 31, 2017. Read More

J Clin Ultrasound 2020 Oct 11;48(8):493-497. Epub 2020 Aug 11.

Ministry of Health Ankara City Hospital, Bilkent, Ankara, 06800, Turkey.

In Turkey, the triad of prior cesarean section (CS), placenta previa, and placenta accreta spectrum is worth of concern. Here, we present an unpublished complication of placenta percreta-induced uterine rupture: ovarian vein thrombosis (OVT) protracting into the inferior vena cava (IVC) in a woman with a previous CS and placenta previa. We propose the integration of the sub-xiphoid transabdominal long axis of the IVC into the point-of-care ultrasound practice with color Doppler to establish the diagnosis of complicated OVT. Read More

Int J Urol 2020 11 9;27(11):1002-1007. Epub 2020 Aug 9.

Department of Plastic Surgery, National Defense Medical College, Tokorozawa, Saitama, Japan.

Objectives: Pubectomy is an ancillary technique used to increase exposure of the disrupted urethra and reduce anastomotic tension, which can be difficult for inexperienced surgeons. The objective of the present study was to illustrate the use of an air drill enabling delicate and precise bone resection in pubectomy for delayed anastomotic urethroplasty for pelvic fracture urethral injury.

Methods: Between 2009 and 2019, 88 male patients underwent delayed anastomotic urethroplasty with pubectomy for pelvic fracture urethral injury. Read More

Pan Afr Med J 2020 28;36:44. Epub 2020 May 28.

Département de Gynécologie et Obstétrique, Cliniques Universitaires de Kinshasa, Faculté de Médecine de l'Université de Kinshasa, Kinshasa, République Démocratique du Congo.

Despite all the health policies implemented in our developing countries, uterine rupture (RU) remains common. They are severe and involve maternal and fetal prognosis. Among the multiple risk factors, the most common cited in the literature is C-section scar. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Aug;52(4):794-798

Ureteropelvic junction obstruction (UPJO) is characterized by decreased flow of urine down the ureter and increased fluid pressure inside the kidney. Open pyeloplasty had been regarded as the standard management of UPJO for a long time. Laparoscopic pyeloplasty reports high success rates, for both retroperitoneal and transperitoneal approaches, which are comparable to those of open pyeloplasty. Read More

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Aug;52(4):646-650

Objective: To evaluate the clinical effects and characteristics of combined transperineal and transpubic urethroplasty for patients with complex pelvic fracture urethral distraction defect (PFUDD).

Methods: We retrospectively reviewed the clinical data of 17 male patients with complex posterior PFUDD from January 2010 to December 2019. The complications included urethrorectal fistulas in 2 patients (11. Read More

Medicine (Baltimore) 2020 Jul;99(31):e21448

Department of Ultrasound, the First Affiliated Hospital of Hainan Medical University, Haiko, China.

To investigate the diagnostic performance of ultrasound (US) for pregnant women with previous caesarean section (CS) occurring lower uterine segment (LUS) dehiscence and rupture.107 pregnant women with previous CS and LUS thickness of 1.0 mm or less were recruited, the LUS and myometrium was measured, and US findings suggestive of uterine rupture were compared with findings at laparotomy. Read More

Brachytherapy 2020 Sep - Oct;19(5):574-583. Epub 2020 Jul 15.

Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

Purpose: MRI-assisted radiosurgery (MARS) is a modern technique for prostate brachytherapy that provides superior soft tissue contrast. The purpose of this analysis was to evaluate treatment planning factors associated with urinary toxicity, particularly damage to the membranous urethra (MUL) and external urethral sphincter (EUS), after MARS.

Material And Methods: We retrospectively reviewed 227 patients treated with MARS. Read More

Neurourol Urodyn 2020 07;39 Suppl 3:S148-S155

Female, Functional and Restorative Urology Unit, University College London Hospitals, London, UK.

Aims: This article reviews the clinical outcomes and basic science related to negative effects of radiotherapy (RT) on the lower urinary tract (LUT) when used to treat pelvic malignancies.

Methods: The topic was discussed at the 2019 meeting of the International Consultation on Incontinence-Research Society during a "think tank" session and is summarized in the present article.

Results: RT is associated with adverse effects on the LUT, which may occur during treatment or which can develop over decades posttreatment. Read More