2,297 results match your criteria Trauma Lower Genitourinary


[A CASE OF RETROPERITONEAL HEMORRHAGE CAUSED BY THE INSERTION OF A URETERAL ACCESS SHEATH. A RARE COMPLICATION ASSOCIATED WITH FLEXIBLE TRANSURETHRAL LITHOTRIPSY (fTUL)].

Nihon Hinyokika Gakkai Zasshi 2018 ;109(1):50-53

Department of Urology, Toyohashi Municipal Hospital.

A 77-year-old man with a right kidney stone was admitted to our hospital. A ureteroscope was introduced into the ureter without dilation under direct vision. We then performed flexible transurethral lithotripsy (f-TUL) using a ureteral access sheath and successfully fragmented the stone and extracted almost all the stone fragments without any complications. Read More

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http://dx.doi.org/10.5980/jpnjurol.109.50DOI Listing
February 2019
2 Reads

Health-related Quality of Life and Toxicity After Single-fraction High-dose-rate Brachytherapy With External Beam Radiotherapy for Localized and Locally Advanced Prostate Cancer.

Anticancer Res 2019 Jan;39(1):477-486

Department of Integrative Cancer Therapy and Urology, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan

Background/aim: To evaluate the treatment outcomes, toxicity and health-related quality of life (HRQOL) in prostate cancer (PCa) patients who underwent single-fraction high-dose-rate brachytherapy (single-fraction HDR-BT) with external beam radiotherapy (EBRT).

Materials And Methods: From April 2014 to October 2017, treatment outcomes and toxicity of 85 patients who underwent single-fraction HDR-BT of 13 Gy, followed by 46 Gy EBRT in 23 fractions, were examined. HRQOL of 53 patients was evaluated using the Expanded Prostate Cancer Index Composite (EPIC), International Prostate Symptom Score (IPSS)/QOL index, International Index of Erectile Function 5 (IIEF-5), and 36-Item Short Form Survey (SF-36) scores through one year. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13137DOI Listing
January 2019
6 Reads

Pelvic Complications After Prostate Cancer Radiation Therapy and Their Management: An International Collaborative Narrative Review.

Eur Urol 2019 Mar 17;75(3):464-476. Epub 2018 Dec 17.

Division of Urology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada; Institute for Health Policy, Management & Evaluation, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Context: Radiotherapy used for treating localized prostate cancer is effective at prolonging cancer-specific and overall survival. Still, acute and late pelvic toxicities are a concern, with gastrointestinal (GI) and genitourinary (GU) sequelae being most common as well as other pelvic complications.

Objective: To present a critical review of the literature regarding the incidence and risk factors of pelvic toxicity following primary radiotherapy for prostate cancer and to provide a narrative review regarding its management. Read More

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http://dx.doi.org/10.1016/j.eururo.2018.12.003DOI Listing
March 2019
3 Reads

Urethral Trauma Following Pelvic Fracture From Horseback Saddle Horn Injury Versus Other Mechanisms of Pelvic Trauma.

Urology 2018 Nov 14. Epub 2018 Nov 14.

Division of Urology, Department of Surgery, University of Utah, Salt Lake City, UT.

Objective: To examine the rate of urethral trauma and pubic symphysis diastasis in saddle horn injury, which occurs when horseback riders are bucked into the air and land with their perineum striking the rigid saddle horn, compared to pelvic fracture from other mechanisms.

Methods: A retrospective review was performed of male patients presenting to our level-1 trauma center with pelvic ring fractures between January 1, 2001 and December 30, 2016. Demographics, injury severity score, mechanism of injury (saddle horn vs other), pubic symphysis diastasis, and lower genitourinary (GU) injuries (bladder and urethra) were identified in the trauma registry. Read More

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http://dx.doi.org/10.1016/j.urology.2018.11.003DOI Listing
November 2018
8 Reads

Bladder and ureteral injuries during benign hysterectomy: an observational cohort analysis in New York State.

World J Urol 2018 Nov 7. Epub 2018 Nov 7.

Department of Urology, Columbia University Medical Center, 161 Ft. Washington Ave 11th Floor, New York, NY, 10032, USA.

Purpose: Hysterectomy (Hys) is the most common non-urologic surgery associated with iatrogenic genitourinary (GU) injury. We present the largest known population-based evaluation of GU injury related to benign Hys.

Methods: The New York Statewide Planning and Research Cooperative System (SPARCS) was queried by ICD-9 and CPT codes. Read More

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http://dx.doi.org/10.1007/s00345-018-2541-yDOI Listing
November 2018
1 Read

The role of melatonin in preventing ovarian tissue damage in rats exposed to magnetic fields

Turk J Med Sci 2018 Oct 31;48(5):1073-1079. Epub 2018 Oct 31.

Objectives: We observed the efficacy of melatonin in preventing ovarian tissue damage in rats exposed to magnetic fields. Materials and methods: Forty rats were divided into four treatment groups: Group 1, control group (n = 10); Group 2, melatonin administration only (n = 10); Group 3, magnetic field exposure only (n = 10); Group 4, magnetic field exposure with melatonin administration (n = 10). The magnetic field was applied at a dose of 20 μT for 30 min/day for 10 days. Read More

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http://dx.doi.org/10.3906/sag-1707-98DOI Listing
October 2018
1 Read

Biocompatible dialysis fluids for peritoneal dialysis.

Cochrane Database Syst Rev 2018 10 26;10:CD007554. Epub 2018 Oct 26.

Department of Renal Medicine, Singapore General Hospital, 20 College Street, Singapore, Singapore, 169856.

Background: Biocompatible peritoneal dialysis (PD) solutions, including neutral pH, low glucose degradation product (GDP) solutions and icodextrin, have previously been shown to favourably influence some patient-level outcomes, albeit based on generally sub-optimal quality studies. Several additional randomised controlled trials (RCT) evaluating biocompatible solutions in PD patients have been published recently. This is an update of a review first published in 2014. Read More

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http://doi.wiley.com/10.1002/14651858.CD007554.pub3
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http://dx.doi.org/10.1002/14651858.CD007554.pub3DOI Listing
October 2018
4 Reads

Hematologic Toxicity of Conformal Radiotherapy and Intensity Modulated Radiotherapy in Prostate and Bladder Cancer Patients

Asian Pac J Cancer Prev 2018 Oct 26;19(10):2803-2806. Epub 2018 Oct 26.

Department of Radiotherapy Planning, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Poland. Email:

Background: The purpose of this study was to compare hematologic adverse effects and hematologic toxicity (HT) of pelvic irradiation in patients treated with conformal radiotherapy (CRT) and intensity modulated radiotherapy (IMRT) for radical treatment of prostate and bladder cancer. Methods: A group of 115 patients with prostate or bladder cancer treated with definitive radical radiotherapy was evaluated retrospectively. Blood test were taken before and after treatment comprising of following indices: white blood cells (WBC) hemoglobin (HGB), red blood cell (RBC), lymphocyte (LC), neutrophil (NC) and platelet (PLT) count. Read More

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http://journal.waocp.org/article_69800.html
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http://dx.doi.org/10.22034/APJCP.2018.19.10.2803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291062PMC
October 2018
7 Reads

Sodium Fluorescein for Ureteral Jet Detection: A Prospective Observational Study.

JSLS 2018 Jul-Sep;22(3)

Département de gynécologie du CHU de Québec - Université Laval, Québec, QC, Canada.

Background And Objectives: Laparoscopic hysterectomy poses the risk of lower urinary tract injury, and intraoperative recognition of urinary tract injury is often difficult. We sought to evaluate sodium fluorescein coloration of ureteral jets during cystoscopy after laparoscopic hysterectomy and to evaluate surgeons' satisfaction with this method of injury detection.

Methods: This was an observational study, in which data were collected prospectively. Read More

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191068/
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http://dx.doi.org/10.4293/JSLS.2018.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191068PMC
December 2018
15 Reads

Renoprotective Effects of Antroquinonol in Rats with N-Nitro-l-Arginine Methyl Ester-Induced Hypertension.

Nutrients 2018 Oct 17;10(10). Epub 2018 Oct 17.

Department of Nutrition, I-Shou University, Kaohsiung 82445, Taiwan.

Endothelial dysfunction leads to elevation of blood pressure and vascular remodeling, which may result in tissue injuries. The aim of this study was to investigate the mechanisms and effects of antroquinonol on hypertension and related renal injuries. Rats were fed water containing 25 mg/kg/day N-nitro-l-arginine methyl ester (L-NAME) to induce hypertension, and a diet with or without antroquinonol (20 or 40 mg/kg/day) for a 9-week experiment. Read More

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http://www.mdpi.com/2072-6643/10/10/1521
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http://dx.doi.org/10.3390/nu10101521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212859PMC
October 2018
11 Reads

[Influences of hydrogen-rich saline on acute kidney injury in severely burned rats and mechanism].

Zhonghua Shao Shang Za Zhi 2018 Sep;34(9):629-636

Department of Burns, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.

To explore the influences of hydrogen-rich saline on acute kidney injury in severely burned rats and to analyze the related mechanism. Fifty-six Sprague Dawley rats were divided into sham injury group (=8), burn group (=24), and hydrogen-rich saline group (=24) according to the random number table. Rats in sham injury group were treated by 20 ℃ water bath on the back for 15 s to simulate injury, and rats in burn group and hydrogen-rich saline group were inflicted with 30% total body surface area (TBSA) full-thickness scald (hereinafter referred to as burns) by 100 ℃ water bath on the back for 15 s. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1009-2587.2018.09.013DOI Listing
September 2018
3 Reads

Are mechanical and chemical trauma the reason of meatal stenosis after newborn circumcision?

Eur J Pediatr 2019 Jan 2;178(1):77-80. Epub 2018 Oct 2.

Department of Pediatric Surgery, School of Medicine, Koç University Hospital, Topkapı, Maltepe, 34010, Istanbul, Turkey.

Mechanical and chemical trauma are a widely accepted theories to explain the pathogenesis of meatalstenosis after newborn circumcision. The aim of the present study was to explore the theory that an exposed glans is prone to meatal stenosis. This was done by a novel investigation of boys who were born with "hooded prepuce", a condition in which the glans is completely exposed. Read More

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http://link.springer.com/10.1007/s00431-018-3261-4
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http://dx.doi.org/10.1007/s00431-018-3261-4DOI Listing
January 2019
2 Reads

Gossypiboma masquerading as nephrocutaneous fistula.

BMJ Case Rep 2018 Sep 27;2018. Epub 2018 Sep 27.

Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Nephrocutaneous fistula is a rare complication of surgical procedures involving the kidney. Fistula formation is also a complication seen in gossypiboma. We present the case of a patient who was initially suspected to have nephrocutaneous fistula after open pyelolithotomy. Read More

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http://dx.doi.org/10.1136/bcr-2018-225992DOI Listing
September 2018
13 Reads

The Effects of a Life Stress Emotional Awareness and Expression Interview for Women with Chronic Urogenital Pain: A Randomized Controlled Trial.

Pain Med 2018 Sep 24. Epub 2018 Sep 24.

Department of Psychology, Wayne State University, Detroit, Michigan.

Objective: Women with chronic urogenital pain (CUP) conditions have elevated rates of lifetime trauma, relational stress, and emotional conflicts, but directly assessing and treating psychological stress is rarely done in women's health care settings. We developed and tested the effects on patients' somatic and psychological symptoms of a life stress interview that encourages disclosure about stressors and uses experiential techniques to increase awareness of links between stress, emotions, and symptoms.

Methods: In this randomized trial, women with CUP recruited at a multidisciplinary women's urology center received either a single 90-minute life stress interview (N = 37) or no interview (treatment-as-usual control; N = 25). Read More

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http://dx.doi.org/10.1093/pm/pny182DOI Listing
September 2018
4 Reads

Renal azotemia and associated clinical and laboratory findings in dogs with Babesia rossi infection.

Vet Parasitol 2018 Aug 29;260:22-29. Epub 2018 Jul 29.

Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, Onderstepoort 0110, South Africa.

The occurrence of acute kidney injury in canine babesiosis is not well documented. Furthermore, interpretation of urine specific gravity (USG) to assess renal concentrating ability is hampered by the frequent presence of hemoglobinuria in this disease. This cross-sectional study aimed to test the hypothesis that renal azotemia (RA) is underdiagnosed according to current canine babesiosis literature by determining its occurrence at presentation, using urine osmolality instead of USG to measure urinary concentration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03044017183028
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http://dx.doi.org/10.1016/j.vetpar.2018.07.012DOI Listing
August 2018
21 Reads

Renal trauma: the current best practice.

Ther Adv Urol 2018 Oct 10;10(10):295-303. Epub 2018 Jul 10.

Department of Urology, The Chaim Sheba Medical Center, 2 Sheba Road, Tel Hashomer, 5262100, Israel.

The kidneys are the most vulnerable genitourinary organ in trauma, as they are involved in up to 3.25% of trauma patients. The most common mechanism for renal injury is blunt trauma (predominantly by motor vehicle accidents and falls), while penetrating trauma (mainly caused by firearms and stab wound) comprise the rest. Read More

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http://dx.doi.org/10.1177/1756287218785828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120183PMC
October 2018
11 Reads

[Micro-dissection testicular sperm extraction for non-obstructive azoospermia patients with the history of secondary testicular injury].

Zhonghua Nan Ke Xue 2018 08;24(8):681-685

Center of Reproduction, The Sixth Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510620, China.

Objective: To investigate the value of micro- dissection testicular sperm extraction (micro-TESE) in the treatment of non-obstructive azoospermia (NOA) in patients with the history of secondary testicular injury.

Methods: Totally, 121 NOA patients with the history of secondary testicular injury underwent micro-TESE in our hospital from September 2014 to December 2017. We analyzed the correlation of the sperm retrieval rate with the causes of testicular injury and compared the outcomes of the ICSI cycles with the sperm retrieved from the NOA males by micro-TESE (the micro-TESE group) and those with the sperm ejaculated from severe oligospermia patients (sperm concentration <1×10⁶/ml, the ejaculate group). Read More

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August 2018
35 Reads

[Penoplasty with T-shaped incision and three-point fixation for concealed penis].

Zhonghua Nan Ke Xue 2018 Apr;24(4):335-339

Center of Urology and Nephrology, Ningbo First Hospital / Ningbo Hospital of Zhejiang University, Ningbo, Zhejiang 315010, China.

Objective: To search for a safe and effective method of penoplasty with low incidence of complications for concealed penis by evaluating penoplasty with T-shaped incision and three-point fixation in comparison with modified Devine's technique.

Methods: We retrospectively analyzed 169 cases of concealed penis treated in our center by penoplasty with T-shaped incision and three-point fixation (group A, n = 110) or modified Devine's surgery (group B, n = 59). We compared the operation time, postoperative complications, and recurrence rate between the two groups of patients. Read More

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April 2018
9 Reads

Biobrane™ for burns of the pubic region: minimizing dressing changes.

Mil Med Res 2018 08 26;5(1):29. Epub 2018 Aug 26.

Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Singapore, Singapore.

Background: The pubic region is often involved in accidental hot water or soup-spill burns. Most of these wounds are superficial partial thickness burns. Due to their proximity to the urinary system, as well as vaginal and anal openings, these burns are easily contaminated. Read More

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https://mmrjournal.biomedcentral.com/articles/10.1186/s40779
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http://dx.doi.org/10.1186/s40779-018-0177-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109452PMC
August 2018
17 Reads

Probiotic supplements prevented oxonic acid-induced hyperuricemia and renal damage.

PLoS One 2018 24;13(8):e0202901. Epub 2018 Aug 24.

Laboratory of Renal Physiopathology, INC Ignacio Chavez, Mexico City, Mexico.

Hyperuricemia is highly prevalent and especially common in subjects with metabolic, cardiovascular and renal diseases. In chronic kidney disease, hyperuricemia is extremely common, and uric acid (UA) excretion relies on gut uricolysis by gut microbiota. Current therapy for lowering serum UA includes drugs that may produce undesired secondary effects. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202901PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108486PMC
February 2019
20 Reads
3.234 Impact Factor

[Renal damage of indium sulfate on rats].

Wei Sheng Yan Jiu 2018 May;47(3):459-464

College of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.

Objective: To study the renal damage of indium sulfate.

Methods: 32 healthy Wistar rats were randomly and equally divided into 3 dose groups( 52. 3 mg/kg、104. Read More

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May 2018
14 Reads

Antagonistic effects of Spirulina platensis on diazinon-induced hemato-biochemical alterations and oxidative stress in rats.

Environ Sci Pollut Res Int 2018 Sep 25;25(27):27463-27470. Epub 2018 Jul 25.

Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, Oradea, Romania.

Spirulina platensis (SP) is a traditionally used microalga for a wide range of pharmacological activities, including amelioration of heavy metals and pesticides toxicity. This study evaluated the antioxidant and organoprotective effects of SP against diazinon (DZN)-induced subacute toxicity on the blood, heart, liver, and kidneys of male Wistar albino rats. Diazinon (20 mg/kg, subcutaneous) was administered to animals either alone or along with an oral pure SP powder at doses of 500 and 1000 mg/kg. Read More

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http://dx.doi.org/10.1007/s11356-018-2761-0DOI Listing
September 2018
15 Reads
2.830 Impact Factor

Clinicopathological Characteristics, Role of Immunosuppressive Therapy and Progression in IgA Nephropathy with Hyperuricemia.

Kidney Blood Press Res 2018 17;43(4):1131-1140. Epub 2018 Jul 17.

Department of Nephrology, Fujian Provincial Hospital, Fuzhou, China.

Background/aims: The aim of the study was to investigate clinicopathological characteristics, the role of immunosuppressive therapy and renal outcome in IgA nephropathy (IgAN) patients with hyperuricemia.

Methods: 206 biopsy-proven primary IgAN patients were included between January 2010 and December 2015, and divided into two groups: patients without hyperuricemia (n=122), and patients with hyperuricemia (n=84). The clinicopathological features, response, renal outcome and safety were recorded. Read More

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http://dx.doi.org/10.1159/000491809DOI Listing
November 2018
10 Reads

Simulated management of urinary tract injury during robotic pelvic surgery utilizing the porcine model.

J Robot Surg 2018 Jul 16. Epub 2018 Jul 16.

Department of Genitourinary Oncology, MCC-GU Program, H. Lee Moffitt Cancer Center and Research Institute and University of South Florida Morsani College of Medicine, Magnolia Drive, Tampa, FL, 33612, USA.

Urologic injury is an infrequent but serious complication of pelvic surgery. Training in the assessment and management of this injury might be enhanced through animated simulation. Our objective was to assess the intraoperative management of urologic injury with robotic pelvic surgery using a simulated injury animal model. Read More

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http://dx.doi.org/10.1007/s11701-018-0852-zDOI Listing

High dose-rate tandem and ovoid brachytherapy in cervical cancer: dosimetric predictors of adverse events.

Radiat Oncol 2018 Jul 16;13(1):129. Epub 2018 Jul 16.

Department of Radiation Oncology, University of Virginia School of Medicine, 1240 Lee Street, Box 800383, Charlottesville, VA, 22908, USA.

Background: Brachytherapy (BT) is a vital component of the curative treatment of locally advanced cervical cancer. The American Brachytherapy Society has published guidelines for high dose rate (HDR) BT with recommended dose limits. However, recent reports suggest lower doses may be needed to avoid toxicity. Read More

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http://dx.doi.org/10.1186/s13014-018-1074-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048838PMC
July 2018
4 Reads

Renal dysfunctions/injury in adult epilepsy patients treated with carbamazepine or valproate.

Expert Rev Clin Pharmacol 2018 Aug 25;11(8):819-824. Epub 2018 Jul 25.

a Department of Neurology and Psychiatry , Assiut University Hospital , Assiut , Egypt.

Objectives: Clinical and subclinical laboratory evidence of renal proximal tubular dysfunction had been reported in children with epilepsy as an adverse effect of some antiepileptic drugs (AEDs). This study aimed to determine kidney function in adult patients with monosymptomatic epilepsy of unknown etiology and treated with valproate (VPA) or carbamazepine (CBZ).

Methods: This study included 60 patients [mean age of 33. Read More

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http://dx.doi.org/10.1080/17512433.2018.1501556DOI Listing
August 2018
13 Reads

Superselective microcoil embolization of the vasa recta of sigmoid artery for hemorrhaging after laparoscopic adnexectomy for corpus luteum hematoma with severe adhesion.

J Obstet Gynaecol Res 2018 Aug 28;44(8):1487-1491. Epub 2018 Jun 28.

Department of Obstetrics and Gynecology, Gifu Prefectural Tajimi Hospital, Tajimi, Gifu, Japan.

A 44-year-old multipara woman was referred because of the sudden onset of left lower abdominal pain. Corpus luteum hematoma was suspected and conservatively managed. Two days later, due to worsening of abdominal symptoms, emergency laparoscopic surgery was performed. Read More

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http://dx.doi.org/10.1111/jog.13689DOI Listing
August 2018
13 Reads

Boldine Improves Kidney Damage in the Goldblatt 2K1C Model Avoiding the Increase in TGF-β.

Int J Mol Sci 2018 Jun 25;19(7). Epub 2018 Jun 25.

Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Alameda #340, Santiago 8331150, Chile.

Boldine, a major aporphine alkaloid found in the Chilean boldo tree, is a potent antioxidant. Oxidative stress plays a detrimental role in the pathogenesis of kidney damage in renovascular hypertension (RVH). The activation of the renin-angiotensin system (RAS) is crucial to the development and progression of hypertensive renal damage and TGF-β is closely associated with the activation of RAS. Read More

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http://dx.doi.org/10.3390/ijms19071864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073111PMC
June 2018
2 Reads

Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus.

PLoS One 2018 20;13(6):e0198013. Epub 2018 Jun 20.

Division of Nephrology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America.

Nephrin (Nphs1) is an adhesion protein that is expressed at the podocyte intercellular junction in the glomerulus. Nphs1 mutations in humans or deletion in animal genetic models results in a developmental failure of foot process formation. A number of studies have shown decrease in expression of nephrin in various proteinuric kidney diseases as well as in animal models of glomerular disease. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198013PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010211PMC
December 2018
6 Reads

Vaginal delivery of 2nd trimester spontaneous abortion through ruptured lower uterine segment.

Taiwan J Obstet Gynecol 2018 Jun;57(3):464-465

Department of Obstetrics and Gynecology, Guangzhou Women and Children's Medical Center, 9 Jinsui Road, Tianhe District, Guangzhou, Guangdong, 510623, China. Electronic address:

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http://dx.doi.org/10.1016/j.tjog.2018.04.026DOI Listing

Assessment of Renal Pathological Changes in Lupus Nephritis Using Diffusion Weighted Imaging: A Multiple Correspondence Analysis.

Kidney Blood Press Res 2018 30;43(3):847-859. Epub 2018 May 30.

Department of Radiology, Tianjin Medical University General Hospital, Tianjin, China.

Background/aims: Renal pathological changes affect the motion of water molecules, which can be detected using diffusion-weighted imaging (DWI). The current study was performed to explore the correlation between renal tissue pathological injuries and DWI iconographical parameters in lupus nephritis (LN).

Methods: Twenty adult patients with LN and 11 healthy volunteers were recruited. Read More

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http://dx.doi.org/10.1159/000490333DOI Listing
October 2018
26 Reads

Resveratrol promotes the embryonic development of vitrified mouse oocytes after in vitro fertilization.

In Vitro Cell Dev Biol Anim 2018 Jun 29;54(6):430-438. Epub 2018 May 29.

Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, 845 Lingshan Road, Shanghai, 200135, China.

Vitrification of oocytes is closely associated with the lower embryonic developmental potential, which involves the cryopreservation injury occurred during vitrification. It indicates that vitrification may need to be further optimized. Therefore, we studied the effects of resveratrol, an antioxidant, on the developmental potential of vitrified mouse oocytes after in vitro fertilization. Read More

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http://dx.doi.org/10.1007/s11626-018-0262-6DOI Listing
June 2018
33 Reads
1.150 Impact Factor

The protective effects of alpha lipoic acid on methotrexate induced testis injury in rats.

Biomed Pharmacother 2018 Jan 20;97:1486-1492. Epub 2017 Nov 20.

Department of Medical Pharmacology, School of Medicine, Cukurova University, Adana, Turkey.

Methotrexate (MTX) is frequently used in the treatment of several diseases including cancers, rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, and dermatomyositis. Previously, chemotherapeutic agents have been reported to cause permanent azoospermia and infertility in men. Methotrexate has been also shown to damage the seminiferous tubules of the testicles, lower the sperm count, and cause genetic mutations (in DNA) in sperm. Read More

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http://dx.doi.org/10.1016/j.biopha.2017.11.078DOI Listing
January 2018
4 Reads

Physician assessed and patient reported urinary morbidity after radio-chemotherapy and image guided adaptive brachytherapy for locally advanced cervical cancer.

Radiother Oncol 2018 06 18;127(3):423-430. Epub 2018 May 18.

Department of Oncology, Aarhus University Hospital, Denmark.

Background And Purpose: The EMBRACE study is a prospective multi-institutional study on MRI guided adaptive brachytherapy (IGABT) in locally advanced cervix cancer (LACC). This analysis describes early to late urinary morbidity assessed by physicians and patients (PRO).

Material And Methods: A total of 1176 patients were analysed. Read More

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http://dx.doi.org/10.1016/j.radonc.2018.05.002DOI Listing
June 2018
18 Reads
4.363 Impact Factor

Retrospective study on the management and follow-up of 18 patients with a mid-urethral sling penetrating the urethra or bladder.

J Gynecol Obstet Hum Reprod 2018 Sep 18;47(7):289-297. Epub 2018 May 18.

Department of Urology, Private Hospital Sainte Marie, Ramsay General de Santé, 4 allée Saint Jean des Vignes, 71100 Chalon-sur-Saône, France.

Introduction: The mid-urethral sling (MUS) procedure is the gold-standard for the surgical treatment of stress urinary incontinence (SUI). Urethro-vesical sling exposure is one of the most serious complications of this procedure. We describe the treatment and follow-up of 18 patients with bladder or urethral sling exposure. Read More

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http://dx.doi.org/10.1016/j.jogoh.2018.05.007DOI Listing
September 2018
10 Reads

Charged-Iron-Particles Found in Galactic Cosmic Rays are Potent Inducers of Epithelial Ovarian Tumors.

Radiat Res 2018 08 21;190(2):142-150. Epub 2018 May 21.

Departments of a   Medicine.

Astronauts traveling in deep space are exposed to high-charge and energy (HZE) particles from galactic cosmic rays. We have previously determined that irradiation of adult female mice with iron HZE particles induces DNA double-strand breaks, oxidative damage and apoptosis in ovarian follicles, causing premature ovarian failure. These effects occur at lower doses than with conventional photon irradiation. Read More

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http://www.bioone.org/doi/10.1667/RR15028.1
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http://dx.doi.org/10.1667/RR15028.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6112765PMC
August 2018
1 Read

Effects of Intratesticular Hematoma on Testis Microstructure, Spermatogenesis, and Testosterone Production: Defining a Cutoff Point for Significant Intratesticular Hematoma.

Urology 2018 Aug 16;118:80-86. Epub 2018 May 16.

Department of Urology, Shiraz University of Medical Sciences, Shiraz, Iran.

Objective: To evaluate the effects of different degrees of intratesticular hematoma (ITH), a major consequence of blunt testis trauma, on testis microstructure and function. We determined a cutoff point for significant vs nonsignificant ITH.

Methods: Seventy male rats were divided into 7 equal groups. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00904295183046
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http://dx.doi.org/10.1016/j.urology.2018.05.005DOI Listing
August 2018
64 Reads
2.190 Impact Factor

Repair of urethral defects by an adipose mesenchymal stem cell‑porous silk fibroin material.

Mol Med Rep 2018 Jul 9;18(1):209-215. Epub 2018 May 9.

Department of Urology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, P.R. China.

The aim of the present study was to determine whether it was possible to repair urethral defects with a material of adipose mesenchymal stem cells (ADMSCs)‑porous silk fibroin (SF). A total of 39 male New Zealand white rabbits were randomly divided into a control group, an SF group and a bromodeoxyuridine (BrdU)‑labeled ADMSCs‑SF group (SSF group; n=13/group). Defects were made by resecting the posterior urethral wall. Read More

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http://www.spandidos-publications.com/10.3892/mmr.2018.9001
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http://dx.doi.org/10.3892/mmr.2018.9001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059671PMC
July 2018
7 Reads

Effects of water-borne copper and lead on metabolic and excretion rate of bahaii loach (Turcinoemacheilus bahaii).

Environ Toxicol Pharmacol 2018 Jun 30;60:176-183. Epub 2018 Apr 30.

Young Researchers and Elites Club, Science and Research Branch, Islamic Azad University, Tehran, Iran. Electronic address:

Beyond the role of anthropogenic activities, natural sources of metal contaminations are still controversial, together counting, however, as a major threat to inland and coastal waters, becoming an even more prominent stressor for aquatic life. To address the effects of metals on the physiological response of fish, standard metabolic rate (SMR), maximum metabolic rate (MMR), aerobic scope (AS) and factorial aerobic scope (FAS) as well as specific rate of ammonia excretion (J) of Turcinoemacheilus bahaii were determined following different water-borne Cu and Pb treatments. Following LC-96 h determination, 72 fish (BW = 1. Read More

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http://dx.doi.org/10.1016/j.etap.2018.04.023DOI Listing
June 2018
4 Reads

Maternal Body Mass Index and Anovaginal Distance in Active Phase of Term Labor.

Biomed Res Int 2018 7;2018:1532949. Epub 2018 Mar 7.

Department of Obstetrics and Gynecology and Department of Clinical and Experimental Medicine, Linköping University, S-581 85 Linköping, Sweden.

Introduction: To evaluate if there was a difference in the anovaginal distance (AVD) measured by transperineal ultrasound between obese and normal weight women.

Material And Methods: A prospective observational study including 207 primiparous women at term in first stage of labor. Transperineal ultrasound with a vaginal probe was used to measure the AVD. Read More

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http://dx.doi.org/10.1155/2018/1532949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863348PMC
September 2018

Rare foreign body in bladder: A case report.

Medicine (Baltimore) 2018 Apr;97(17):e0519

Rationale: The bladder is the most common site of foreign bodies in the urinary tract. Presenting complaints in patients with a foreign body are urinary retention, dysuria, frequent urination, decreased urine volume, nocturia, hematuria, painful erection, as well as pain in the urethra and pelvis.

Patient Concerns: A 50-year-old married male presented with complaints of severe lower abdominal pain and dysuria. Read More

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http://dx.doi.org/10.1097/MD.0000000000010519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944513PMC
April 2018
1 Read

Ultrasound Predictability of Lower Uterine Segment Cesarean Section Scar Thickness.

J Coll Physicians Surg Pak 2018 May;28(5):361-364

Department of Radiology, Sharif Medical and Dental College, Lahore.

Objective: The objective of this study is to find out association between scar thickness, assessed sonographically, and intraoperative findings (IOF).

Study Design: Descriptive study.

Place And Duration Of Study: Department of Gynecology and Obstetrics, Sharif Medical and Dental College, Lahore, from June 2016 to April 2017. Read More

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https://www.jcpsp.pk/data/view.php?id=2898&type=pdf&
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http://dx.doi.org/10.29271/jcpsp.2018.05.361DOI Listing
May 2018
11 Reads

Rupture of the scarred and unscarred gravid uterus: Outcomes and risk factors analysis.

Taiwan J Obstet Gynecol 2018 Apr;57(2):248-254

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Tao-Yuan, Taiwan; Chang Gung University College of Medicine, Tao-Yuan, Taiwan. Electronic address:

Objective: To study the maternal and fetal outcomes and assess the risk factors in patients with rupture at the lower-segment or non-lower-segment scarred, or unscarred gravid uterus.

Materials And Methods: Gravid patients with uterine rupture were retrospectively collected in Chang-Gung Memorial Hospital from November 2004 to July 2017. The rupture timing and location in association with maternal and fetal outcomes were collected as well as the possible risk factors including surgical history and interval prior to conception were analyzed. Read More

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http://dx.doi.org/10.1016/j.tjog.2018.02.014DOI Listing
April 2018
1 Read

[Lower Uterine Segment Trial: A pragmatic open multicenter randomized trial].

Gynecol Obstet Fertil Senol 2018 Apr 4;46(4):427-432. Epub 2018 Apr 4.

Centre d'épidémiologie clinique, CHU Hôtel-Dieu, université Paris Descartes, AP-HP, France.

Background: The data from literature show that trial of labor and elective repeat cesarean delivery after a prior cesarean delivery both present significant risks and benefits, and these risks and benefits differ for the woman and her fetus. The benefits to the woman can be at the expense of her fetus and vice-versa. This uncertainty is compounded by the scarcity of high-level evidence that preclude accurate quantification of the risks and benefits that could help provide a fair counseling about a trial of labor and elective repeat cesarean delivery. Read More

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http://dx.doi.org/10.1016/j.gofs.2018.03.005DOI Listing
April 2018
16 Reads

Soluble klotho as a marker of renal fibrosis and podocyte injuries in human kidneys.

PLoS One 2018 28;13(3):e0194617. Epub 2018 Mar 28.

Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.

Klotho deficiency is relevant to renal fibrosis and podocyte injury in vivo and in vitro. We examined whether histological findings of renal biopsy specimens were associated with the levels of soluble klotho in humans. We investigated renal biopsy specimens of 67 patients and detailed microscopic findings were reviewed. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194617PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874023PMC
July 2018
17 Reads

Minimally Invasive management of delayed recognition iatrogenic ureteric injury.

Ulster Med J 2017 Sep 12;86(3):181-184. Epub 2017 Sep 12.

Department of Urology, Belfast City Hospital, Department of Urology, Craigavon Area Hospital, Co. Down BT63 5QQ.

Introduction: Iatrogenic ureteric injuries are a rare but serious complication of abdomino-pelvic surgery which can be associated with significant morbidity. 65-80% of ureteric trauma is only identified in the postoperative period. Current guidelines recommend stent insertion or urinary diversion via percutaneous nephrostomy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849975PMC
September 2017
10 Reads

Volume and Shape Assessment of Renal Radiofrequency Ablation Lesion.

Urology 2018 Jun 22;116:229.e7-229.e11. Epub 2018 Mar 22.

Urogenital Research Unit, State University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:

Objective: To evaluate the microscopic characteristics and quantify the volume of a radiofrequency ablation (RFA) lesion.

Methods: Ten male pigs were submitted to laparoscopic RFA. An RFA needle was introduced in the lower pole of the left kidney to create a lesion expected to be a sphere of 2. Read More

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http://dx.doi.org/10.1016/j.urology.2018.03.015DOI Listing
June 2018
1 Read

In utero heat stress causes reduced testicular area at puberty, reduced total sperm production, and increased sperm abnormalities in boars.

Anim Reprod Sci 2018 May 24;192:126-135. Epub 2018 Feb 24.

Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, United States. Electronic address:

In utero stress has been shown to negatively affect intact male rats and mice, though very little research has been conducted in boars. The objectives of the present studies were to determine the effects of in utero heat stress (IUHS) on postnatal development and the response to postnatal heat stress of boars. Ten boars were selected at weaning from litters subjected to IUHS or in utero thermoneutral (IUTN) during 30-60 days of gestation. Read More

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http://dx.doi.org/10.1016/j.anireprosci.2018.02.022DOI Listing
May 2018
2 Reads

Effect of reduced glutathione supplementation on cryopreservation induced sperm cryoinjuries in Murrah bull semen.

Anim Reprod Sci 2018 May 9;192:171-178. Epub 2018 Mar 9.

C. V. Sc. and A.H., DUVASU, Mathura, 281 001, Uttar Pradesh, India.

The experiment was conducted to study cryopreservation induced sperm cryoinjuries and the protective effect of reduced Glutathione supplementation in Murrah bull semen. A total of 20 semen ejaculates were split into two parts after initial examination and were extended in glycerolated egg yolk TRIS diluter (Control group) and glycerolated egg yolk TRIS diluter + 0.5 mM reduced Glutathione (Treatment Group). Read More

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http://dx.doi.org/10.1016/j.anireprosci.2018.03.005DOI Listing

Management of Major Blunt Renal Injury: A Twelve-Year Review at an Urban, Level I Trauma Hospital.

Am Surg 2018 Mar;84(3):451-454

The aim of this study was to describe the management of severe blunt renal injuries at a Level I trauma hospital. Data were collected through a record review of patients admitted from January 1, 2000, to December 31, 2011. These data were compiled as part of our hospital's participation in the Nonoperative Management of Grade IV and V Blunt Renal Injuries: A Research Consortium of New England Centers for Trauma Study. Read More

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