J Clin Gastroenterol 2022 Jan 10. Epub 2022 Jan 10.
Division of Gastroenterology, Hepatology, and Nutrition Department of Biostatistics Division of Interventional Radiology, Virginia Commonwealth University Division of Gastroenterology and Hepatology, Hunter-Holmes McGuire Veterans Affairs Medical Center, Richmond, VA Section of Digestive Diseases, Yale University, New Haven, CT.
Background: Liver biopsy and hepatic venous pressure gradient (HVPG), the gold standard for assessing advanced fibrosis (AF) and clinically significant portal hypertension (CSPH), are invasive, costly, and time-consuming.
Goal: We investigated if the combination of fibrosis index based on 4 factors (FIB-4) and liver stiffness measure (LSM) can identify AF and more importantly, CSPH.
Patients And Methods: Patients with chronic liver disease referred for transjugular liver biopsy were analyzed retrospectively. Read More