1,130 results match your criteria Transient Global Amnesia


New-Onset Transient Global Amnesia: A Clinical Challenge in an Air Medical Transportation Pilot With a History of Coronavirus Disease 2019.

Air Med J 2022 Jul-Aug;41(4):402-405. Epub 2022 May 21.

Aerospace and Sub-Aquatic Medical Faculty, Aja University of Medical Sciences, Tehran, Iran. Electronic address:

A 43-year-old male Bell 214C helicopter pilot presented to the emergency ward with flu-like syndrome. His nasopharyngeal severe acute respiratory syndrome coronavirus 2 real-time polymerase chain reaction test was positive, and a chest computed tomographic scan confirmed coronavirus disease 2019 pneumonia. He was admitted, received treatment, was discharged, and returned to flying. Read More

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Forgetting the Unforgettable: Transient Global Amnesia Part I: Pathophysiology and Etiology.

J Clin Med 2022 Jun 12;11(12). Epub 2022 Jun 12.

Neurology Unit, Stroke Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, RE, Italy.

Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of a temporary memory disorder with a profound anterograde amnesia and a variable impairment of the past memory. Since the first description, dating back over 60 years, several cases have beenreported in the literature. Nevertheless, TGA remains one of the most mysterious diseases in clinical neurology. Read More

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COVID-19 Vaccine-Associated Transient Global Amnesia: A Disproportionality Analysis of the WHO Safety Database.

Front Pharmacol 2022 20;13:909412. Epub 2022 May 20.

Department of Pharmacology and Pharmacovigilance Center of Nice, University Hospital of Nice, Nice, France.

Coronavirus disease 2019 (COVID-19) spread rapidly, resulting in a global pandemic for which vaccines were quickly developed. As their safety continues to be monitored, cases of transient global amnesia (TGA) following mRNA vaccination with elasomeran have been reported. TGA is characterized by sudden onset of anterograde amnesia with preservation of other cognitive functions and resolution within 24 h. Read More

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Pathophysiological insight into transient global amnesia from quantitative electroencephalography.

Neurobiol Dis 2022 Aug 28;170:105778. Epub 2022 May 28.

iMediSync Inc., Seoul, Republic of Korea; National Standard Reference Data Center for Korean EEG, Seoul National University College of Nursing, Republic of Korea. Electronic address:

Transient global amnesia (TGA) is recognized as a benign memory disorder, with characteristic clinical and imaging features. However, the pathophysiology of TGA remains elusive. This study aims to elucidate the pathophysiological changes underlying TGA by exploring the brain activities. Read More

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Hot off the press: MRI sensitivity for transient global amnesia.

Acad Emerg Med 2022 May 27. Epub 2022 May 27.

University of Western Ontario, Goderich, Ontario, Canada.

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SREDA in a transient global amnesia patient: the overlooked link?

Acta Neurol Belg 2022 May 18. Epub 2022 May 18.

Section of Clinical Neurophysiology, Department of Neurology, La Paz University Hospital, Paseo de La Castellana, 261, 28046, Madrid, Spain.

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Combined abnormal findings of MRI-SPECT-EEG suggest vulnerability to ischemia in transient global amnesia.

J Neurol Sci 2022 Jul 9;438:120273. Epub 2022 May 9.

Department of Neuropsychiatry, Keio University School of Medicine. 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

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Neuroimaging and Electroencephalographic Correlation in Patients with Transient Global Amnesia: Clinical Case Series.

Clin EEG Neurosci 2022 May 11:15500594221101399. Epub 2022 May 11.

First Department of Neurology, 37782Aristotle University of Thessaloniki, AHEPA University Hospital, Thessaloniki, Greece.

. To determine if there is any correlation between the electroencephalographic and neuroimaging findings in patients with Transient Global Amnesia (TGA). We retrospectively reviewed files of the First Department of Neurology of AHEPA University Hospital, including patients with a clinical diagnosis of TGA. Read More

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Acute-onset amnesia: transient global amnesia and other causes.

Pract Neurol 2022 Jun 3;22(3):201-208. Epub 2022 May 3.

Department of Brain Sciences, Imperial College London, London, UK.

Acute-onset amnesia is a dramatic neurological presentation that can cause considerable concern to both patient and clinician. The patient typically presents with an inability not only to retain new memories but also to access previously acquired memories, suggesting disturbance of hippocampal function. Transient global amnesia (TGA) is the most common cause of acute-onset amnesia, and is characterised by a profound anterograde and retrograde amnesia that typically lasts for up to 24 hours. Read More

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[Memory Loss - a Case of Sudden Amnesia].

Praxis (Bern 1994) 2022 Apr;111(6):358-361

Stroke Center, Klinik für Neurologie, Klinik Hirslanden Zürich/Universität Basel, Basel, Schweiz.

Memory Loss - a Case of Sudden Amnesia Transient global amnesia (TGA) is a clinical diagnosis with typical signs of an anterograde and retrograde amnesia. The underlying mechanisms are yet unknown, different hypotheses are being discussed. Ultimately there is a temporary dysfunction of the hippocampi. Read More

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Bedside echocardiography evaluation of a male with transient global amnesia.

J Am Coll Emerg Physicians Open 2022 Apr 11;3(2):e12716. Epub 2022 Apr 11.

Department of Emergency Medicine HCA Healthcare/USF Morsani College of Medicine GME/Brandon Regional Hospital Brandon Brandon FL USA.

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The remains of the day: neuropsychological findings in postacute transient global amnesia.

J Neurol 2022 Apr 8. Epub 2022 Apr 8.

Department of Neurology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68135, Mannheim, Germany.

Introduction: Current clinical diagnostic criteria of transient global amnesia (TGA) require the episode to completely resolve within 24 h. Small case series investigating the neuropsychological profiles obtained during the first days after TGA are inconclusive, with some suggesting the persistence of memory deficits.

Methods: In this retrospective observational study, neuropsychological data of 185 TGA patients obtained during the first days following an attack were analysed. Read More

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The Significance of Atrial Fibrillation in Patients With Transient Global Amnesia.

Front Neurol 2022 7;13:830727. Epub 2022 Mar 7.

Department of Neurology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Background And Purpose: The etiology of transient global amnesia (TGA) remains unclear in a large subset of patients. We aimed to determine the clinical and radiological characteristics of TGA-patients with suspected acute micro-embolic stroke on diffusion-weighted imaging (DWI).

Methods: TGA-patients that had new DWI hippocampal lesions (DWI+) were compared to DWI negative TGA-patients (DWI-). Read More

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Acute amnesia caused by left fornix infarction: A case report of an unusual entity.

Radiol Case Rep 2022 May 18;17(5):1626-1630. Epub 2022 Mar 18.

Department of Radiology, Nassau University Medical Center, East Meadow, NY, USA.

Cerebral infarction is an uncommon and unusual cause of acute amnesia. The fornix is a white matter tract bundle that plays an important function in memory. We present the case of a 60-year-old male presenting with altered mental status and acute onset amnesia with CT and MR imaging demonstrating an acute left fornix infarct. Read More

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Re: Hippocampal infarction: redefining transient global amnesia.

Authors:
Andrew J Larner

Neurol Sci 2022 06 22;43(6):3997. Epub 2022 Mar 22.

Walton Centre for Neurology and Neurosurgery, Cognitive Function Clinic, Liverpool, UK.

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Hippocampal infarction: redefining transient global amnesia.

Neurol Sci 2022 Jul 4;43(7):4281-4286. Epub 2022 Mar 4.

Hospital Universitario San Ignacio, Bogotá, D.C, Colombia.

Background And Aims: Transient global amnesia (TGA) is a clinical syndrome characterized by sudden anterograde amnesia not accompanied by other neurological symptoms. There is no consensus on the underlying pathophysiological mechanism. However, diffusion-weighted imaging (DWI) of the magnetic resonance imaging (MRI) has demonstrated hippocampal lesions in as many as 50% of cases. Read More

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A Case of Transient Global Amnesia: A Rare Diagnosis.

Cureus 2022 Jan 26;14(1):e21637. Epub 2022 Jan 26.

Internal Medicine, MacNeal Hospital, Berwyn, USA.

Transient global amnesia (TGA) is a syndrome characterized by a loss of anterograde memory with a less prominent loss in retrograde episodic memory that resolves within 24 hours or less. In this report, we present a rare case of a 62-year-old male who presented to the emergency department with sudden onset confusion and memory loss. Prior to this, the patient had no significant medical or psychiatric history. Read More

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January 2022

Transient global amnesia: Model, mechanism, hypothesis.

Authors:
Andrew J Larner

Cortex 2022 04 31;149:137-147. Epub 2022 Jan 31.

Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom. Electronic address:

Transient global amnesia (TGA) is a rare but well-described neurological disorder characterised by an acute self-limited episode of dense anterograde amnesia with retrograde amnesia of variable extent. Although the clinical phenomenology, neuropsychology, neuroimaging, prognosis, and precipitating and predisposing factors of TGA are well described, the pathogenesis is not currently understood. Existing proposals - epileptic seizure, stroke or transient ischaemic attack, migraine aura - all have shortcomings. Read More

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Basilar Artery Embolism Mimicking Transient Global Amnesia in a 61-Year-Old Female: A Case Report.

Case Rep Neurol 2022 Jan-Apr;14(1):19-24. Epub 2022 Feb 1.

Clinic of Neurology and Neurophysiology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Transient global amnesia (TGA) is a self-limiting neurological condition that temporarily affects patients' ability to access and store memories. So far, its etiology is unknown; however, ischemic origin has been discussed in the past. We present the case of a 61-year-old female with clinical appearance of TGA. Read More

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February 2022

"Broken Heart" and "Broken Brain": Which Connection?

Cardiol Res 2022 Feb 28;13(1):65-70. Epub 2021 Dec 28.

Swiss Cardiovascular Centre, Bern University Hospital, Bern, Switzerland.

The interconnections between brain and heart are increasingly recognized. Takotsubo cardiomyopathy, also known as "broken heart syndrome", is characterized by a cardiovascular dysfunction provoked by an emotional or stressful situation. Similar events can trigger a neurological pathology called transient global amnesia. Read More

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February 2022

Hippocampal subfield involvement in patients with transient global amnesia.

J Neuroimaging 2022 Mar 2;32(2):264-267. Epub 2022 Feb 2.

Department of Neurology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Background And Purpose: Transient global amnesia (TGA) is a rare neurological disorder causing a transient disturbance of episodic long-term memory. Its etiology remains yet to be identified; the only consistently reported findings in patients with TGA are small hyperintense lesions in the hippocampus on diffusion-weighted magnetic resonance imaging (DWI). The aim of this study was to define whether these lesions are subfield specific, as suggested previously. Read More

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Transient Global Amnesia Following Coil Embolization for a Basilar-tip Aneurysm: Case Reports of Two Patients.

NMC Case Rep J 2021 29;8(1):113-116. Epub 2021 Apr 29.

Department of Neurosurgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Transient global amnesia (TGA) can be caused by medications, ischemia, metabolic abnormalities, and seizures. We describe two cases of TGA following coil embolization for a basilar-tip aneurysm. A 73-year-old woman developed transient acute anterograde amnesia after coil embolization for a basilar-tip aneurysm. Read More

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Transient Global Amnesia.

Am Fam Physician 2022 01;105(1):50-54

Medical University of South Carolina, Greenwood, SC, USA.

Transient global amnesia (TGA) is a clinical syndrome characterized by anterograde amnesia, mild retrograde amnesia, and confusion up to 24 hours. Most commonly seen in patients older than 50 years, TGA results from the temporary impairment of short-term memory formation. Clinically, patients have time disorientation and often ask repeated questions regarding the day's events. Read More

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January 2022

Recurrent amnesia caused by early seizures after hippocampal infarction: a case report.

BMC Neurol 2022 Jan 10;22(1):18. Epub 2022 Jan 10.

Klinik und Poliklinik für Neurologie, Kopf- und Neurozentrum, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: We report the case of a patient with recurrent episodes of disturbed memory suggestive of transient epileptic amnesia, and a focal hippocampal lesion typically associated with transient global amnesia. We argue how careful consideration of clinical, electrophysiological and imaging findings can resolve this apparent contradiction and lead to a diagnosis of early symptomatic post-stroke seizures that links brain structure to function in a new, clinically relevant way.

Case Presentation: A 70-year-old patient was identified in clinical practice in our tertiary care centre and was evaluated clinically as well as by repeated electroencephalography and magnetic resonance imaging. Read More

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January 2022

Transient global amnesia: a condition with chronobiological variation?

J Neurol 2022 06 9;269(6):3351-3352. Epub 2022 Jan 9.

Department of Neurology, Hospital Egas Moniz, Centro Hospitalar Lisboa Ocidental, Rua da Junqueira 126, 349-019, Lisbon, Portugal.

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Stroke Mimics in the Acute Setting: Role of Multimodal CT Protocol.

AJNR Am J Neuroradiol 2022 02 30;43(2):216-222. Epub 2021 Dec 30.

Department of Neuroradiology (A.C.), Inselspital Bern, University of Bern, Bern, Switzerland.

Background And Purpose: Ischemic stroke can be mimicked by nonischemic conditions. Due to emphasis on the rapid treatment of acute ischemic stroke, it is crucial to identify these conditions to avoid unnecessary therapies and potential complications. We investigated the performance of the multimodal CT protocol (unenhanced brain CT, CTA, and CTP) to discriminate stroke mimics from acute ischemic stroke. Read More

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February 2022

Transient global amnesia following deliberate self-harm by hanging: Case report and review.

Ind Psychiatry J 2021 Oct 22;30(Suppl 1):S328-S330. Epub 2021 Oct 22.

Department of Psychiatry, AFMC, Pune, Maharashtra, India.

A 25-year-old female was hospitalized subsequent to an attempt to hang herself. She was unconscious for a few minutes but responded to initial resuscitative measures. Relevant investigations, including X-ray neck, computed tomography scan brain, and electroencephalogram were normal. Read More

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October 2021

Cerebellar Ischemia Presenting as Transient Global Amnesia.

Cogn Behav Neurol 2021 12 2;34(4):319-322. Epub 2021 Dec 2.

Department of Neurology, The Ohio State University, Columbus, Ohio.

Transient global amnesia (TGA) consists of acute-onset anterograde amnesia and typically resolves within 24 hours. Reported etiologies of TGA include transient ischemia to the hippocampus or thalamus, migraine, venous flow abnormalities, and epilepsy. There are no reports of cerebellar ischemia as an etiology of TGA. Read More

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December 2021

Transient Global Amnesia (TGA): Younger Age and Absence of Cerebral Microangiopathy Are Potentially Predisposing Factors for TGA Recurrence.

Front Neurol 2021 27;12:736563. Epub 2021 Oct 27.

Department of Neurology, Evangelisches Klinikum Bethel, University Hospital OWL, University Bielefeld, Campus Bielefeld-Bethel, Bielefeld, Germany.

Transient global amnesia (TGA) is defined by an acute memory disturbance of unclear etiology for a period of less than 24 h. TGA occurs as a single event in most cases. Prevalence rates of recurrent TGA vary widely from 5. Read More

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October 2021

Transient global amnesia and stroke: not that benign?

Stroke Vasc Neurol 2022 04 8;7(2):92-93. Epub 2021 Nov 8.

Dipartimento di Scienze Biomediche e Neuromotorie, Università di Bologna, Bologna, Italy.

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