Cortex 2022 04 31;149:137-147. Epub 2022 Jan 31.
Cognitive Function Clinic, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom. Electronic address:
Transient global amnesia (TGA) is a rare but well-described neurological disorder characterised by an acute self-limited episode of dense anterograde amnesia with retrograde amnesia of variable extent. Although the clinical phenomenology, neuropsychology, neuroimaging, prognosis, and precipitating and predisposing factors of TGA are well described, the pathogenesis is not currently understood. Existing proposals - epileptic seizure, stroke or transient ischaemic attack, migraine aura - all have shortcomings. Read More