237 results match your criteria Transient Acantholytic Dermatosis


Cutaneous manifestations in SARS-CoV-2 infection (COVID-19): a French experience and a systematic review of the literature.

J Eur Acad Dermatol Venereol 2020 Jun 26. Epub 2020 Jun 26.

Department of Dermatology, Hôpital Cochin, AP-HP, Groupe Hospitalier Paris Centre Cochin-Hôtel Dieu-Broca, 89 rue d'Assas, 75006, Paris, France.

Skin manifestations have been increasingly reported in the setting of COVID-19. However, their incidence and presentation are debated, and the role, direct or undirect, of SARS-CoV-2 in their pathogenesis has yet to be determined. In this work, we aimed to analyze our experience in a French referral center and to perform a systematic review of the literature to evaluate the incidence and prognosis of cutaneous lesions observed in COVID-19 patients. Read More

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http://dx.doi.org/10.1111/jdv.16775DOI Listing

Treatment of transient acantholytic dermatosis with liquid nitrogen.

JAAD Case Rep 2020 Apr 25;6(4):341-343. Epub 2020 Mar 25.

Division of Dermatology, Harbor-UCLA Medical Center, Torrance, California.

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http://dx.doi.org/10.1016/j.jdcr.2020.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103660PMC

BRAF inhibitor and hairy cell leukemia-related transient acantholytic dermatosis.

Dermatol Online J 2020 Feb 15;26(2). Epub 2020 Feb 15.

Department of Dermatology, University of New Mexico, School of Medicine, Albuquerque, NM.

Grover disease (GD) is an acquired, nonfamilial, nonimmune mediated, transient or persistent acantholytic dermatosis. Herein, we present a 72-year-old man who had clinical and histopathologic findings of GD following two weeks of treatment with vemurafenib without MEK inhibitor. The patient was successfully treated with topical emollients and a high-potency corticosteroid. Read More

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February 2020

Transient acantholytic dermatosis in a patient with prostate cancer.

Dermatol Online J 2020 Feb 15;26(2). Epub 2020 Feb 15.

Foundation University Medical College, Islamabad.

Transient acantholytic dermatosis (TAD) is a relatively common entity that has been also noted to occur in patients with cancer. Herein, we describe a case of transient acantholytic dermatosis occurring in a patient with a history of prostate cancer status post radiation, now being treated with combination therapy with pembrolizumab and carboplatin-pemetrexed for advanced lung adenocarcinoma. Our case emphasizes the importance of being cognizant of TAD and its associations, particularly in cancer patients. Read More

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February 2020

Comment on "Grover disease: review of subtypes with a focus on management options".

Int J Dermatol 2020 05 17;59(5):e135-e136. Epub 2020 Mar 17.

Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/ijd.14844DOI Listing

Hyperkeratotic Skin Adverse Events Induced by Anticancer Treatments: A Comprehensive Review.

Drug Saf 2020 May;43(5):395-408

Oncodermatology, Institut Claudius REGAUD and Institut Universitaire du Cancer Toulouse Oncopole, 1 avenue Irène Joliot-Curie 31059, Toulouse Cedex 9, France.

Hyperkeratotic skin adverse events are a group of toxic effects, characterized by the disruption of epidermal homeostasis and interaction with keratinocyte proliferation/differentiation or keratinocyte survival, and frequently reported with systemic anticancer treatments. These types of reactions include hand-foot skin reaction or palmoplantar keratoderma, induced psoriasis, keratosis pilaris-like or pityriasis rubra pilaris-like rashes, Grover's disease, and contact hyperkeratosis. Cutaneous squamoproliferative lesions are also described because of the presence of abnormal keratinocyte proliferation. Read More

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http://dx.doi.org/10.1007/s40264-020-00907-6DOI Listing

Grover's Disease in a Kidney Transplant Recipient.

Acta Dermatovenerol Croat 2019 Sep;27(3):192-194

Professor Nikolina Bašić-Jukić, MD, PhD, Department of Nephrology, Arterial , Hypertension, Dialysis and Transplantation, University Hospital Centre Zagreb, Kišpaticeva 12, 10000 Zagreb, Croatia;

Dear Editor, It is not unusual for patients with renal insufficiency to develop skin pathologies. There are reports in the literature of increased incidence of calciphylaxis, pruritus, perforating dermatoses, and porphyria cutanea tarda in this patient population (1). Although it is quite rare, Grover's disease (GD) has been reported in several patients with renal insufficiency, but only once in a renal transplant recipient (2). Read More

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September 2019
5 Reads
0.581 Impact Factor

Neutrophil-rich Variant of Persistent Bullous Grover's Disease.

Acta Derm Venereol 2019 Dec;99(13):1282-1283

Department of Dermatology, Osaka National Hospital, 2-1-14 Hoenzaka Chuo-ku, Osaka 540-0006, Japan.

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http://dx.doi.org/10.2340/00015555-3316DOI Listing
December 2019
2 Reads

Pityriasis rubra pilaris-like eruption in the setting of transient acantholytic dermatosis.

JAAD Case Rep 2019 Aug 5;5(8):733-735. Epub 2019 Aug 5.

Department of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa.

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http://dx.doi.org/10.1016/j.jdcr.2019.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698694PMC
August 2019
2 Reads

Unilateral segmental Darier's disease associated with neuropsychiatric disorders.

Clin Case Rep 2019 Jul 3;7(7):1362-1364. Epub 2019 Jun 3.

Department of Dermatology Wayne State University School of Medicine Detroit Michigan.

Unilateral segmental Darier's disease (DD) is a rare variant of DD that presents with erythematic lesions in a unilateral distribution without other associated features of DD. Although diagnosis is challenging, unilateral segmental DD should be considered for an acantholytic dermatosis in a unilateral distribution and a history of neuropsychiatric disorders. Read More

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http://dx.doi.org/10.1002/ccr3.2243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637367PMC
July 2019
3 Reads

Coexistence of Pemphigus Foliaceus and Grover Disease After a Radical Surgery for Basal Cell Carcinoma.

Am J Dermatopathol 2019 Oct;41(10):744-746

Department of Dermatology, Hospital General Universitario de Valencia, Valencia, Spain.

The differential diagnosis of Grover disease (GD) includes pemphigus foliaceus. However, the focal nature of the histologic findings and negative direct immunofluorescent point to the diagnosis of GD. It has been associated with a variety of systemic and cutaneous diseases, but its association with other primary acantholytic disorders has been rarely documented. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001419DOI Listing
October 2019
7 Reads

Grover’s Disease Treated With Total Skin Electron Beam Radiotherapy

J Drugs Dermatol 2019 Apr;18(4):392-393

Persistent Grover's disease can cause significant symptoms of pruritus thereby decreasing quality of life. Many patients undergo successful conservative management of their disease; however, a subset of patients is recalcitrant despite multiple lines of therapy. Accordingly, we present, to our knowledge, the first reported case of recalcitrant Grover's disease treated successfully with radiotherapy. Read More

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April 2019
7 Reads

Persistent generalized Grover disease: complete remission after treatment with oral acitretin.

Dermatol Online J 2019 Mar 15;25(3). Epub 2019 Mar 15.

Department of Dermatology, School of Medicine, University of Patras, Patras.

Grover disease (GD) is a disorder of unknown origin, clinically characterized by the occurrence of pruritic, erythematous or brownish papules and papulovesicles, which histologically reveal four different patterns of acantholysis. Usually, the eruption is self-limited and spontaneously remit within a few weeks. In some cases, however, it may persist for months or even years and show a therapy-resistant course. Read More

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March 2019
3 Reads

[Grover's-like drug eruption under anti-PD-1 therapy for metastatic melanoma].

Ann Dermatol Venereol 2018 Dec 9;145(12):802-803. Epub 2018 Nov 9.

Service de dermatologie, centre hospitalier Lyon-Sud, 165, chemin du grand Revoyet, 69495 Pierre Bénite cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.annder.2018.10.016DOI Listing
December 2018
26 Reads

Porokeratosis-Like Grover Disease: More Than an Acantholytic Pattern.

Actas Dermosifiliogr 2019 May 5;110(4):332-334. Epub 2018 Nov 5.

Programa de Dermatopatología, Universidad CES, Medellín, Antioquia, Colombia.

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http://dx.doi.org/10.1016/j.ad.2018.02.032DOI Listing
May 2019
9 Reads

Grover disease and bullous pemphigoid: a clinicopathological study of six cases.

Clin Exp Dermatol 2019 Jul 27;44(5):524-527. Epub 2018 Sep 27.

Department of Dermatology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Grover disease (GD) is an idiopathic dermatosis that typically manifests as itchy papules over the trunk in middle-aged men. Bullous pemphigoid (BP) is an autoimmune bullous disease that affects older people. Not only are the two diseases easily distinguishable on clinical grounds, they are also characterized by differences in histopathology, pathogenesis and response to treatment Thus, the co-occurrence of these two conditions in the same patient is usually considered coincidental. Read More

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http://doi.wiley.com/10.1111/ced.13789
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http://dx.doi.org/10.1111/ced.13789DOI Listing
July 2019
18 Reads

Monolateral Grover's Disease with Blaschkoid Distribution.

Acta Dermatovenerol Croat 2017 Dec;25(4):31-311

Nicola di Meo, MD, Dermatology Department, University of Trieste, Ospedale Maggiore di Trieste, Piazza Ospedale 1, IV Piano Palazzina Infettivi, 34100 Trieste, Italy;

Dear Editor, Grover's disease, also known as transient acantholytic dermatosis, is an idiopathic and acquired pruritic eruption of small vesicles and erythematous papules, classically on the central chest. The pathogenesis is not clearly defined, although heat sweating and occlusion have been interpreted as predisposing factors. We describe a case of monolateral acantholytic eruption with blaschkoid distribution in a patient treated with an orthopedic bandage for a shoulder injury. Read More

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December 2017
21 Reads

Suprabasal acantholytic dermatologic toxicities associated checkpoint inhibitor therapy: A spectrum of immune reactions from paraneoplastic pemphigus-like to Grover-like lesions.

J Cutan Pathol 2018 Oct 24;45(10):764-773. Epub 2018 Jul 24.

Section of Dermatopathology, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Checkpoint inhibitors (CPIs) restore the function of effector immunocytes to target and destroy cancer cells. Immune-related adverse events (irAEs) are a consequence of immune reactivation, with unpredictable inflammatory response, loss of self-tolerance, and development of autoimmunity. Adverse events from CPIs that present as dermatologic toxicities have diverse clinical and histopathologic features. Read More

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http://dx.doi.org/10.1111/cup.13312DOI Listing
October 2018
63 Reads

Clinico-Pathological Study of 4 Cases of Pseudoherpetic Grover Disease: The Same as Vesicular Grover Disease.

Am J Dermatopathol 2018 Jun;40(6):445-448

Departments of Dermatology, and.

Introduction: Grover disease (GD) was described with 4 histopathological patterns, but later wide histopathological studies found additional ones including vesicular GD. From 2014, 2 new patterns, GD with epidermolytic hyperkeratosis and pseudoherpetic GD, have been proposed.

Objectives: The authors present 4 cases of pseudoherpetic GD and review the 6 previously published cases to better characterize this variant clinically and histopathologically. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001058DOI Listing
June 2018
66 Reads

Primary cutaneous follicle center lymphoma mimicking folliculitis.

Cutis 2018 Jan;101(1):E30-E33

Department of Dermatology, University of Texas MD Anderson Cancer Center, Houston, and Department of Dermatology, University of Texas Medical School, Houston, USA.

Primary cutaneous follicle center lymphoma (PCFCL) is the most common type of cutaneous B-cell lymphoma. The cutaneous manifestations of PCFCL typically include solitary erythematous or violaceous plaques, nodules, or tumors of varying sizes. Grouped lesions also may be observed, but multifocal disease is rare. Read More

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January 2018
42 Reads

Grover Disease With Epidermal Dysmaturation Pattern: A Common Histopathologic Finding.

Am J Dermatopathol 2018 Sep;40(9):642-646

Department of Pathology, Wake Forest University, School of Medicine, Medical Center Boulevard, Winston Salem, NC.

Background: Grover disease is an entity whose diagnosis is based on clinicopathologic correlation. Histopathologically, focal acantholysis is the most common finding. In some cases, there is prominent squamous atypia which can prove to be very challenging and the lesion may be confused with an epidermal neoplasm. Read More

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http://Insights.ovid.com/crossref?an=00000372-201809000-0000
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http://dx.doi.org/10.1097/DAD.0000000000001112DOI Listing
September 2018
15 Reads

Role of Immune Status in Chemotherapy-Induced Transient Acantholytic Dermatosis.

Skinmed 2017;15(6):483-484. Epub 2017 Dec 1.

Section of Dermatology, Department of Medicine, University of Chicago, Pritzker School of Medicine; Chicago, IL;

A 79-year-old man with a recent diagnosis of acute myeloblastic leukemia received induction chemotherapy with daunorubicin and cytarabine, plus moxifloxacin and fluconazole prophylaxis. Approximately 2 weeks later, an asymptomatic eruption appeared on his trunk. He then developed a neutropenic fever and was started on aztreonam, vancomycin, voriconazole, and amikacin and was transferred to our facility from an outside hospital. Read More

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July 2019
10 Reads

Dermoscopic characteristics of transient acantholytic dermatosis (Grover's disease).

Eur J Dermatol 2017 12;27(6):648-650

Department of Dermatology, Venerology, and Allergology; University Medical Center, Ruprecht-Karl University, Heidelberg, Germany.

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http://dx.doi.org/10.1684/ejd.2017.3104DOI Listing
December 2017
15 Reads

Stellate erosion: the dermoscopic Nikolsky sign?

Eur J Dermatol 2017 12;27(6):659-660

First Dermatology Department, Aristotle University of Thessaloniki, Delfon 124, 54643, Thessaloniki, Greece.

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http://dx.doi.org/10.1684/ejd.2017.3114DOI Listing
December 2017
11 Reads

Grover's disease: dermoscopy, reflectance confocal microscopy and histopathological correlation.

Dermatol Pract Concept 2017 Jul 31;7(3):51-54. Epub 2017 Jul 31.

Dermatology Clinic, University of Catania, Italy.

Grover's disease is a benign condition of unknown origin characterized clinically by an erythematous papulovesicular eruption and histopathologically by intraepidermal clefting and four different patterns of acantholysis: Darier-like, pemphigus-like, spongiotic, and Hailey-Hailey-like. A case of a 54-year-old female affected by Grover's disease and showing a Darier-like histopathological pattern is described. Polarized light dermoscopy (PLD) revealed the presence of polygonal, star-like shaped yellowish/brownish areas of various sizes surrounded by a thin whitish halo. Read More

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http://dx.doi.org/10.5826/dpc.0703a11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661164PMC
July 2017
13 Reads

Pruritic eruption on the chest.

Cutis 2017 Aug;100(2):84;94;96

Department of Dermatology, Department of Pathology, Saint Louis University School of Medicine, Missouri, USA.

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August 2017
9 Reads

Atypical features and systemic associations in extensive cases of Grover disease: A systematic review.

J Am Acad Dermatol 2017 Nov 14;77(5):952-957.e1. Epub 2017 Sep 14.

Department of Pathology, University of California, San Francisco, California. Electronic address:

Background: Grover disease is an acantholytic disorder that typically occurs on the trunk of older individuals, primarily white men, in association with heat and xerosis. Cases with extensive and/or atypical distributions have been reported.

Objective: To review the literature characterizing the population, morphology, associations, and disease course of extensive or atypical eruptions of Grover disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173194
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http://dx.doi.org/10.1016/j.jaad.2017.06.041DOI Listing
November 2017
30 Reads

Grover's disease in a patient with pemphigus vulgaris.

Int J Dermatol 2017 Oct 2;56(10):1052-1054. Epub 2017 Aug 2.

Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Kurume, Fukuoka, Japan.

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http://dx.doi.org/10.1111/ijd.13718DOI Listing
October 2017
12 Reads

Chronic inflammatory acantholytic dermatosis: a previously under-recognized or emerging variant of Grover disease.

Clin Exp Dermatol 2017 Aug 21;42(6):683-685. Epub 2017 Jun 21.

Dermatology Department, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Kent Lodge, Thomas Drive, Liverpool, L14 3LB, UK.

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http://dx.doi.org/10.1111/ced.13169DOI Listing
August 2017
12 Reads

["Indolent" pigmented skin tumor for more than 20 years].

Hautarzt 2017 Oct;68(10):855-858

Hautarztpraxis, Konstanz, Deutschland.

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http://dx.doi.org/10.1007/s00105-017-3998-0DOI Listing
October 2017
2 Reads

Histopathological aspects of cutaneous erythematous-papular eruptions induced by immune checkpoint inhibitors for the treatment of metastatic melanoma.

Int J Dermatol 2017 May 10;56(5):527-533. Epub 2017 Feb 10.

Oncodermatology department, CIC, CHU, Nantes, France.

Background: Immune checkpoint blockade therapy (ICBT) for the treatment of melanoma has led to an important improvement of overall survival in advanced stage patients. However, secondary cutaneous maculopapular eruptions (CMPEs) are frequent and remain poorly characterized.

Methods: We performed a retrospective analysis of melanoma patients from our institution who developed CMPEs during ICBT. Read More

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http://dx.doi.org/10.1111/ijd.13540DOI Listing
May 2017
36 Reads

Erratum to: A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

J Immunother Cancer 2017 18;5. Epub 2017 Jan 18.

Department of Melanoma Medical Oncology, University of Texas-MD Anderson Cancer Center, Houston, TX USA.

[This corrects the article DOI: 10.1186/s40425-016-0157-6.]. Read More

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http://dx.doi.org/10.1186/s40425-017-0208-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244590PMC
January 2017
24 Reads

Pseudoherpetic transient acantholytic dermatosis (Grover disease): case series and review of the literature.

Authors:
Kiran Motaparthi

J Cutan Pathol 2017 May 16;44(5):486-489. Epub 2017 Feb 16.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

A total of 3 cases of pseudoherpetic transient acantholytic dermatosis (Grover disease) are presented, followed by a brief review of prior reports. All 3 patients were above the age of 60 and presented with a pruritic eruption composed of papules with or without vesicles distributed on the trunk. For all 3 patients, the clinical differential diagnosis included drug eruption but did not include Grover disease; in 1 patient, the clinical impression included herpesvirus infection. Read More

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http://dx.doi.org/10.1111/cup.12909DOI Listing
May 2017
8 Reads

Dermoscopy of Grover disease.

J Am Acad Dermatol 2017 Feb;76(2S1):S60-S63

Dermatology Unit, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1016/j.jaad.2016.07.031DOI Listing
February 2017
20 Reads

Sudden Onset of an Itchy Papular Eruption: A Quiz.

Acta Derm Venereol 2017 05;97(5):667-668

Department of Dermatology, Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.2340/00015555-2588DOI Listing
May 2017
47 Reads

A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

J Immunother Cancer 2016 20;4:55. Epub 2016 Sep 20.

Department of Melanoma Medical Oncology, University of Texas-MD Anderson Cancer Center, Houston, TX USA.

Background: Immune related adverse events (irAEs) are common side effects of checkpoint inhibitory (CPI) therapies targeting CTLA-4 and PD-1/PD-L1. Grover's disease is an uncommon dermatologic condition with unclear pathogenesis previously reported as an irAE with ipilimumab.

Case Presentation: We report an additional case of ipilimumab-induced Grover's disease. Read More

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http://dx.doi.org/10.1186/s40425-016-0157-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028978PMC
September 2016
24 Reads

Paraneoplastic Itch Management.

Curr Probl Dermatol 2016 23;50:149-54. Epub 2016 Aug 23.

Paraneoplastic itch occurs as the result of a systemic reaction to an underlying malignancy. Paraneoplastic itch is most commonly associated with lymphoproliferative malignancies and solid tumors that result in cholestasis. Paraneoplastic itch may occur in the absence of a primary rash or in association with dermatologic conditions such as erythroderma, acanthosis nigricans, dermatomyositis, Grover's disease, and eruptive seborrheic keratosis. Read More

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https://www.karger.com/Article/FullText/446060
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http://dx.doi.org/10.1159/000446060DOI Listing
April 2017
45 Reads

Grover's-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy.

J Immunother Cancer 2016 16;4:47. Epub 2016 Aug 16.

Cantonal Hospital Baselland, Institute of Pathology, Mühlemattstrasse 11, CH-4410 Liestal, Switzerland.

Background: Dermatologic toxicity is an important adverse effect of immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death 1 receptor (PD-1) or PD ligand 1 (PD-L1). Skin toxicity most commonly includes a maculopapular erythematous rash and pruritus. Rarely life threatening complications such as Steven's Johnson syndrome or toxic epidermal necrolysis may occur. Read More

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http://dx.doi.org/10.1186/s40425-016-0151-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986338PMC
August 2016
13 Reads

Transient acantholytic dyskeratosis (Grover's disease) after bone marrow transplantation.

Australas J Dermatol 2016 Nov 30;57(4):e120-e122. Epub 2016 Jun 30.

Westmead Hospital, Sydney, New South Wales, Australia.

Cutaneous eruptions in recipients of allogeneic haematopoietic stem cell transplantation (AHSCT) are frequent, and common aetiologies include graft-versus-host disease (GVHD), drug reactions, viral infections and engraftment syndrome. Transient acantholytic dermatosis or Grover's disease has been described in oncology patients and it is rarely reported after AHSCT. However, this benign and self-limiting condition should be histologically distinguished from other, more serious entities, mainly stage IV GVHD, in order to avoid inappropriate treatment with corticosteroids and intensive immunosuppression. Read More

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http://dx.doi.org/10.1111/ajd.12517DOI Listing
November 2016
33 Reads

Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15-year analysis of dermatopathologic data.

Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.

Temple University School of Medicine, Philadelphia, PA, USA.

Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.

Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.

Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More

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http://dx.doi.org/10.1111/ijd.13229DOI Listing
October 2016
56 Reads

Dermoscopy of Grover's disease: Variability according to histological subtype.

J Dermatol 2016 Aug 19;43(8):937-9. Epub 2016 Feb 19.

Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.

Distinguishing Grover's disease from other papular dermatoses is often a troublesome task. According to two relatively recent case reports, dermoscopy may be useful in assisting the diagnosis of such a disorder by showing a peculiar pattern. The aim of this study was to evaluate the dermoscopic features of Grover's disease in a larger series of patients and correlate dermoscopy with histopathological findings. Read More

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http://dx.doi.org/10.1111/1346-8138.13298DOI Listing
August 2016
28 Reads

Dermoscopic features of a case of transient acantholytic dermatosis.

Australas J Dermatol 2017 Feb 14;58(1):50-52. Epub 2016 Jan 14.

Department of Dermatology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.

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http://dx.doi.org/10.1111/ajd.12434DOI Listing
February 2017
14 Reads

Grover's disease in chronic kidney failure.

Nefrologia 2015 17;35(3):331-4. Epub 2015 Jun 17.

Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Ferrol, Ferrol, A Coruña, España.

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http://dx.doi.org/10.1016/j.nefro.2015.05.009DOI Listing
April 2017
15 Reads

Grover's disease and cutaneous melanoma: a fortuitous association or a paraneoplastic case?

G Ital Dermatol Venereol 2015 Dec 10;150(6):756-8. Epub 2015 Jul 10.

Dermatology Unit, Department of Clinical Medicine and Immunologic Science, University of Siena, "Le Scotte" Hospital, Siena, Italy -

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December 2015
8 Reads

Pruritic Papules Following Lumbar Corset Use: A Quiz. Grover's disease.

Acta Derm Venereol 2015 Jul;95(6):762-3

Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.2340/00015555-2071DOI Listing
July 2015
34 Reads

Grover's Disease with Acrosyringeal Acantholysis: A Rare Histological Presentation of an Uncommon Disease.

Indian J Dermatol 2014 Nov;59(6):621-3

Department of Dermatology, Apollo Gleneagles Hospital, Kolkata, West Bengal, India. E-mail:

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http://dx.doi.org/10.4103/0019-5154.143548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248512PMC
November 2014
80 Reads

[Acantholytic dermatosis in patients treated by vemurafenib: 2 cases].

Ann Dermatol Venereol 2014 Nov 23;141(11):689-93. Epub 2014 Oct 23.

Clinique de dermatologie et photobiologie, hôpital Nord, CHU de Grenoble, Cs 10217, boulevard de la-Chantourne-La-Tronche, 38043 Grenoble cedex 9, France.

Background: Acantholytic dyskeratosis under BRAF inhibitors are dermatological diseases rarely reported to date.

Patients And Methods: We report 2 cases of acantholytic dyskeratosis, reaching the trunk and the seborrheic zones, not itchy, appeared one month after the introduction of vemurafenib. The histological analysis was typical of a "Grover-like rash" for the 2 patients. Read More

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http://dx.doi.org/10.1016/j.annder.2014.09.024DOI Listing
November 2014
9 Reads

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection.

Dermatol Pract Concept 2014 Oct 31;4(4):21-7. Epub 2014 Oct 31.

Division of Dermatology, University of California San Diego, San Diego, California.

Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections.

Purpose: To review the histologic differential diagnosis of conditions with epithelial and histiocytic multinucleated giant cells-since multinucleated giant cells in the epidermis are not always pathognomonic of a cutaneous herpes virus infection-and to summarize dermatoses in which herpes virus infection has been observed to coexist. Read More

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http://dx.doi.org/10.5826/dpc.0404a03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230253PMC
October 2014
40 Reads

Pruritic eruption on the chest.

J Fam Pract 2014 Nov;63(11):677-9

Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia. Email:

The fact that this patient's rash was limited to his chest provided an important diagnostic clue. Read More

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November 2014
14 Reads

Cutaneous crystal storing histiocytosis: a report of two cases.

J Cutan Pathol 2015 Feb 24;42(2):136-43. Epub 2014 Nov 24.

Department of Anatomical Pathology, Liverpool Hospital, Liverpool, Australia.

Crystal storing histiocytosis (CSH) is a rare condition where crystals accumulate in the cytoplasm of macrophages and is usually associated with a lymphoplasmacytic neoplasm producing a monoclonal immunoglobulin with kappa light chain. CSH with primary manifestation in the skin is extraordinarily rare and limited to four case reports in the literature. Here we present two cases of cutaneous CSH. Read More

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http://dx.doi.org/10.1111/cup.12413DOI Listing
February 2015
27 Reads