283,379 results match your criteria Transient Acantholytic Dermatosis
J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.
Gastroenterology and Hepatology Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Background: The recommendation in regards to screening for non-alcoholic fatty liver disease (NAFLD) among type 2 diabetes mellitus (T2DM) patients differs in major guidelines.
Aim: To study the prevalence of NALFD and advanced fibrosis among T2DM patients.
Methods: Cross-sectional study of consecutive adult T2DM patients attending the Diabetes Clinic of a university hospital. Read More
Am J Perinatol 2018 Dec 14. Epub 2018 Dec 14.
Department of Neonatal Medicine, Osaka Women's and Children's Hospital, Izumi, Osaka, Japan.
Objective: To assess effects of neonatal transport on transient tachypnea of the newborn (TTN) in outborn term neonates.
Study Design: This retrospective cohort study included 66 term neonates diagnosed with TTN and transported to the Osaka Women's and Children's Hospital neonatal intensive care unit between January 2003 and March 2018. A multivariate logistic regression analysis identified perinatal and neonatal transport factors associated with adverse short-term outcomes defined as mechanical ventilation >48 hours, continuous positive airway pressure >72 hours, pulmonary hemorrhage, and requirement for inhaled nitric oxide, thoracentesis, or surfactant replacement therapy. Read More
PLoS One 2018 14;13(12):e0207139. Epub 2018 Dec 14.
College of Pharmacy, Nanchang University, Nanchang, Jiangxi, P.R. China.
Tumor suppressor genes (TSGs), including Ten-eleven translocation 1 (TET1), are hypermethylated in hepatocellular carcinoma (HCC). TET1 catalytic domain (TET1-CD) induces genome-wide DNA demethylation to activate TSGs, but so far, anticancer effects of TET1-CD are unclear. Here we showed that after HCC cells were transiently transfected with TET1-CD, the methylation levels of TSGs, namely APC, p16, RASSF1A, SOCS1 and TET1, were distinctly reduced, and their mRNA levels were significantly increased and HCC cells proliferation, migration and invasion were suppressed, but the methylation and mRNA levels of oncogenes, namely C-myc, Bmi1, EMS1, Kpna2 and c-fos, were not significantly change. Read More
PLoS One 2018 14;13(12):e0207486. Epub 2018 Dec 14.
University of Nebraska Medical Center, Omaha, NE, United States of America.
Background: Microbubbles (MB) can be compressed to nanometer-sized droplets and reactivated with diagnostic ultrasound; these reactivated MB possess unique imaging characteristics.
Objective: We hypothesized that droplets formed from compressing Definity MB may be used for infarct-enhancement imaging.
Methods: Fourteen rats underwent ligation of their left anterior descending (LAD) artery, and five pigs underwent 90 minute balloon occlusions of their mid LAD. Read More
Int J Food Microbiol 2018 Dec 4;291:197-204. Epub 2018 Dec 4.
Department of Horticulture, University of Georgia, 2360 Rainwater Rd., Tifton, GA 31793-5766, USA.
Plant genotype has been advocated to have an important role in the fate of enteric pathogens residing in lettuce foliage. This study was therefore undertaken under the premise that different pathogen responses could occur in lettuce cultivars with cultivar selection being one of several hurdles in an overall strategy for controlling foodborne pathogens on field-grown produce. Up to eight lettuce cultivars ('Gabriella', 'Green Star', 'Muir', 'New Red Fire', 'Coastal Star', 'Starfighter', 'Tropicana', and 'Two Star') were examined in these experiments in which the plants were subjected to spray contamination of their foliage with pathogens. Read More
Sci Total Environ 2018 Dec 2;657:568-576. Epub 2018 Dec 2.
Department of Agriculture, Food and Environment, University of Pisa, Via del Borghetto 80, Pisa 56124, Italy; CIRSEC, Centre for Climatic Change Impact, University of Pisa, Via del Borghetto 80, Pisa 56124, Italy; Nutrafood Research Center, University of Pisa, Via del Borghetto 80, 56124 Pisa, Italy.
Tropospheric ozone (O) is the most important gaseous pollutant and induces a mass of negative impacts on vegetation at functional and genic levels. The aim of the present study was to investigate the role of reactive oxygen species and signalling molecules in sage plants exposed to O (200 ppb, 5 h). Ozone exposure induced only a transient oxidative burst, as confirmed by the rapid peak of anion superoxide during the first hours of exposure (+16% compared to controls). Read More
Biochimie 2018 Dec 11. Epub 2018 Dec 11.
Respiratory Medicine, Hunan Provincial People's Hospital, No. 61 Jiefang Xi Road, Changsha, 410219, Hunan, PR China; Institute of Respiratory Medicine, Changsha Medical College, No. 1501 Leifeng Road, Changsha, 410219, Hunan, PR China. Electronic address:
The present study was designed to explore the role of transient receptor potential canonical 3 (TRPC3) in nicotine-induced chronic obstructive pulmonary disease (COPD) and its underlying mechanism. In this study, the expression and localization of α5 nicotinic acetylcholine receptor (α5-nAchR) in lung tissues were determined by western blotting and immunohistochemistry. The quantitative real-time PCR (qRT-PCR) analysis was performed to examine the mRNA expression levels of α5-nAchR and TRPC3 in human airway smooth muscle cells (HASMCs). Read More
J Phys Chem B 2018 Dec 14. Epub 2018 Dec 14.
The drying and crystallisation of solution droplets is a problem of broad relevance, determining the micro-structures of particles formed in spray drying, the phase of particles delivered by, for example, aerosol formulations for inhalation therapies, and the impact of aerosols on radiative forcing and climate. The ephemeral nature of free-droplets, particularly when considering the drying kinetics of droplets with highly volatile constituents, has often precluded the accurate measurement of transient properties such as droplet size and composition, preventing the robust assessment of predictive models of droplet drying rates, nucleation and crystallisation. Here, we report novel measurements of the drying kinetics of individual aqueous sodium chloride solution droplets using a comparative-kinetics electrodynamic balance to isolate and trap single aerosol droplets (radius ~ 25 µm). Read More
Langmuir 2018 Dec 14. Epub 2018 Dec 14.
Advancement in high-performance photonics/electronics devices has amplified generated thermal energy making thermal management a bottleneck for the accelerated innovation in these disciplines. While various methods have been used to tackle the thermal management problem, evaporation with nanometer fluid thickness is one of the most promising approaches for future technological demands. Here, we studied thin-film evaporation in nanochannels under absolute negative pressure in both transient and steady-state conditions. Read More
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1477-1479
Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, 100032, China.
To evaluate the operation safety, hearing as well as speech results of cochlear implantation that were applied in patients over 75 years old. A series of patients who were diagnosed as severe to profound sensorineural hearing loss and received cochlear implantation were admitted. The clinical data and rehabilitation effects of the patients who were over 75 years old were summarized. Read More
Isr Med Assoc J 2018 Dec;20(12):792
Department of Family Medicine, Sial Research Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
J Clin Psychiatry 2018 Dec 4;80(1). Epub 2018 Dec 4.
Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, New York, USA.
Background: According to prevailing models and classical reports, abrupt responses to antidepressant medication are not true drug responses but rather transient placebo effects. By contrast, recent reports suggest that early sudden improvements have a lasting effect and appear in most patients receiving medication. Clinical guidelines influenced by these contradictory findings are mixed and confusing. Read More
Psychophysiology 2018 Dec 14:e13310. Epub 2018 Dec 14.
EMG Unit, Neurology Department, Hospital Clinic, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.
All sensory stimuli produce transient excitability changes in various central nervous system circuits. One example is prepulse inhibition (PPI), which is the inhibition generated by a preceding weak stimulus (prepulse) over the reflex response to a subsequent suprathreshold stimulus. The PPI is a ubiquitous phenomenon, common to many different sensory modalities. Read More
J Med Virol 2018 Dec 14. Epub 2018 Dec 14.
Department of Endemic Medicine and Hepatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Background And Aim: Direct acting antiviral has offered treatment of hepatitis C virus (HCV) recurrence post liver transplantation (LT) with an all-oral regimen for short duration, excellent safety profile, and high sustained virological response (SVR). The aim of this study was to evaluate the efficacy and safety of sofosbuvir (SOF)-based regimens in the real world among a cohort of Egyptian patients with recurrent HCV post living donor LT (LDLT).
Methods: Patients with HCV-G4 recurrence post-LDLT were recruited from National Committee of Control of Viral Hepatitis, Egypt, from November 2014 to May 2017. Read More
J Anat 2018 Dec 13. Epub 2018 Dec 13.
Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, Croatia.
The objective of this paper was to collect normative data essential for analyzing the subplate (SP) role in pathogenesis of developmental disorders, characterized by abnormal circuitry, such as hypoxic-ischemic lesions, autism and schizophrenia. The main cytological features of the SP, such as low cell density, early differentiation of neurons and glia, plexiform arrangement of axons and dendrites, presence of synapses and a large amount of extracellular matrix (ECM) distinguish this compartment from the cell-dense cortical plate (CP; towards pia) and large fiber bundles of external axonal strata of fetal white matter (towards ventricle). For SP delineation from these adjacent layers based on combined cytological criteria, we analyzed the sublaminar distribution of different microstructural elements and the associated maturational gradients throughout development, using immunocytochemical and histological techniques on postmortem brain material (Zagreb Neuroembryological Collection). Read More
Macromol Biosci 2018 Dec 13:e1800271. Epub 2018 Dec 13.
Department of Physics, Biomolecular Sciences Institute, Florida International University, FL, 33199, USA.
In-depth understanding of the biophysicochemical interactions at the nano-bio interface is important for basic cell biology and applications in nanomedicine and nanobiosensors. Here, the extracellular surface potential and topography changes of live cell membranes interacting with polymeric nanomaterials using a scanning ion conductance microscopy-based potential imaging technique are investigated. Two structurally similar amphiphilic conjugated polymer nanoparticles (CPNs) containing different functional groups (i. Read More
Echocardiography 2018 Dec 12. Epub 2018 Dec 12.
Cardiology Department, Zagazig University Hospital-Egypt, Zagazig, Egypt.
Background And Aim: Recently, a clear evidence suggests that nonalcoholic fatty liver disease (NAFLD) is associated with an increased risk of incident atrial fibrillation (AF). Yet, the underlying pathogenesis is speculative. Thereby, we aimed to investigate the hypothesis that, interatrial thickness (IAST) and left atrial stiffness (LASt) might have mechanistic links between NAFLD and AF. Read More
Dev Neurobiol 2018 Dec 12. Epub 2018 Dec 12.
Unit on Neural Circuits and Adaptive Behaviors, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892, USA.
Perinatal neurodevelopment involves extensive formation of neural connections and onset of activity-dependent gene expression for synaptic function and plasticity. Exposure to psychostimulants at this stage imposes significant risks for developing cognitive and affective disorders later in life. However, how developmental exposure to psychostimulants may induce long lasting molecular changes relevant to neural circuit function remains incompletely understood. Read More
Am J Transplant 2018 Dec 12. Epub 2018 Dec 12.
Department of Surgery, University of Cambridge, School of Clinical Medicine, Cambridge, United Kingdom.
Tissue resident lymphocytes are present within many organs, and are presumably transferred at transplantation, but their impact upon host immunity is unclear. Here we examine whether transferred donor natural regulatory CD4 T cells (nT-regs) inhibit host alloimmunity and prolong allograft survival. Transfer of donor-strain lymphocytes was first assessed by identifying circulating donor-derived CD4 T cells in 21 consecutive human lung transplant recipients, with three patterns of chimerism apparent: transient; intermediate; and persistent (detectable for up to 6 weeks, 6 months, and beyond one year, respectively). Read More
Curr Protoc Stem Cell Biol 2018 Dec 12:e75. Epub 2018 Dec 12.
Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada.
We have established an in vitro model of the human congenital heart defect (CHD)-associated mutation NKX2.5 R141C. We describe the use of the hanging drop method to differentiate Nkx2. Read More
Catheter Cardiovasc Interv 2018 Dec 8. Epub 2018 Dec 8.
Department of Cardiology, Ehime Niihama Prefectural Hospital, Niihama, Ehime, Japan.
Background: Temporary pace maker is necessary because of transient block or bradycardia during the intracoronary acetylcholine spasm provocation tests based on the Japanese Circulation Society guidelines.
Objectives: We examined the feasibility and safety of the acetylcholine spasm provocation test via the radial artery and brachial vein approach.
Methods: We tried to perform the acetylcholine spasm provocation tests in 252 patients via the radial artery and brachial vein approach procedures during 5 years. Read More
Phys Rev Lett 2018 Nov;121(22):220601
Department of Basic Science, The University of Tokyo, 3-8-1 Komaba, Meguro, Tokyo 153-8902, Japan.
We propose a self-validating scheme to calculate the unbiased responses of quantum many-body systems to external fields of arbitrary strength at any temperature. By switching on a specified field to a thermal pure quantum state of an isolated system, and tracking its time evolution, one can observe an intrinsic thermalization process driven solely by many-body effects. The transient behavior before thermalization contains rich information on excited states, giving the linear and nonlinear response functions at all frequencies. Read More
J Phys Chem Lett 2018 Dec 14. Epub 2018 Dec 14.
We report an experimental study of iodomethane attosecond transient absorption spectroscopy (ATAS) in the region of iodine 4d core-to-valence/Rydberg excitation. Similar to previous atomic experiments, XUV-NIR delay-dependent absorbance changes reflect a light-induced phase due to an NIR-field driven AC Stark shift of the excited states, as well as pathway interferences arising from couplings between neighboring states. As a novel aspect of molecular ATAS, we observe pronounced differences between the ATAS signatures of valence and Rydberg states. Read More
Biochemistry 2018 Dec 14. Epub 2018 Dec 14.
Large parallel gains in the development of both computational resources as well as sampling methods have now made it possible to simulate dissociation events in ligand-protein complexes with all--atom resolution. Such encouraging progress, together with the inherent spatiotemporal resolution associated with molecular simulations, has left their use for investigating dissociation processes brimming with potential, both in rational drug design, where it can be an invaluable tool for determining the mechanistic driving forces behind dissociation rate constants, as well as in force-field development, where it can provide a catalog of transient molecular structures on which to refine force-fields. Although much progress has been made in making force-fields more accurate, reducing their error for transient structures along a transition path could yet prove to be a critical development helping to make kinetic predictions much more accurate. Read More
Ir Med J 2018 09 10;111(8):808. Epub 2018 Sep 10.
Department of Clinical Neurophysiology, St. Vincent’s University Hospital, Elm Park, Dublin 4, Ireland.
Aim To describe a case of acute and transient hand weakness that developed during cardiopulmonary resuscitation (CPR) training. Hereditary neuropathy with liability to pressure palsies (HNPP) should be considered in patients with recurrent, painless motor or sensory neuropathies at sites of peripheral nerve compression. Methods Nerve conduction studies confirmed neuropraxia of the distal ulnar nerve with a mild background demyelinating peripheral neuropathy. Read More
J Cardiol Cases 2014 Apr 5;9(4):165-167. Epub 2014 Feb 5.
National University Heart Centre, Singapore, Singapore.
A 46-year-old man who had failed primary angioplasty to the dominant right coronary artery due to high thrombus burden 2 years previously, presented with non-ST-elevation myocardial infarction following discontinuing antiplatelet therapy for 2 months. Angiography showed occluded right coronary artery with extensive thrombus burden. There was no significant left coronary artery disease. Read More
J Cardiol Cases 2013 Oct 31;8(4):125-128. Epub 2013 Aug 31.
Clinical Cardiology, Maimonides Medical Center, Brooklyn, NY, USA.
Takotsubo cardiomyopathy (TCM) is characterized by a transient depression of contractile function of mid and/or apical segments of the left ventricle with compensatory hyperkinesis of the basal segment. It leads to ballooning of the apex in systole, resembling an octopus trap, hence the name. There have been many different arrhythmias associated with TCM. Read More
J Cardiol Cases 2013 Sep 11;8(3):99-104. Epub 2013 Jul 11.
Department of Cardiology, Mayo Clinic, Mayo College of Medicine, Rochester, MN 55905, USA.
Takotsubo syndrome, also called apical ballooning syndrome, is a clinical entity characterized by transient hypokinesis, akinesis, or dyskinesis of the left ventricular mid and apical segments without flow limiting obstructive coronary lesions. There have been many reported morphologic variants of apical ballooning syndrome based upon distribution of segment involvement including traditional apical, midventricular, and basilar. We present a patient who demonstrated sequential transition of mid-basilar type to classical apical ballooning type. Read More
J Cardiol Cases 2016 Nov 16;14(5):133-135. Epub 2016 Jul 16.
Division of Cardiology, Department of Medicine, Faculty of Medicine, Kindai University, Osaka, Japan.
Cardiac memory is an electrocardiographic manifestation of transient T wave abnormalities, which is observed after abrupt interruption of abnormal ventricular activation. We report a case with preexisting complete left bundle branch block in whom cardiac memory was induced. This cardiac memory was induced by normalization of QRS morphology after development of complete atrioventricular block due to acute inferior myocardial infarction. Read More
J Cardiol Cases 2016 Aug 19;14(2):40-42. Epub 2016 Apr 19.
Department of Radiology, Sir Charles Gairdner Hospital, Perth, WA, Australia.
Calcified bicuspid aortic valves are a commonly encountered clinical problem. Less common and possibly underreported, however, are embolic events secondary to a calcified valve. Events, including stroke and myocardial infarction, have been documented in the literature. Read More
J Cardiol Cases 2016 Jul 1;14(1):21-23. Epub 2016 Apr 1.
Department of Cardiovascular Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Although apical ballooning is the most common morphological type of takotsubo cardiomyopathy, variants have been reported. Several case reports have demonstrated focal takotsubo cardiomyopathy. Most cases had left ventricular wall motion abnormality in the anterolateral segment. Read More
J Cardiol Cases 2016 Apr 11;13(4):121-124. Epub 2016 Feb 11.
Department of Medicine, Division of Cardiology, New York University School of Medicine, New York, NY, USA.
Transient right bundle branch block following blunt cardiac injury is a known but under-recognized manifestation of cardiac contusion. The first case documented in the medical literature occurred in 1952 in a 22-year-old man who was thrown from a motorcycle. Due to their relatively anterior location, the right ventricle and right bundle branch are at particular risk of injury in contusion. Read More
J Cardiol Cases 2015 Oct 27;12(4):133-137. Epub 2015 Jul 27.
National Heart Centre, Singapore.
A rare but serious complication of pericardiocentesis is the development of transient left ventricular dysfunction. In this report, we present a case of a 65-year-old male patient with cardiac tamponade who suffered from acute left ventricular heart failure post-pericardiocentesis. < Acute left ventricular dysfunction is a rare but serious complication of pericardiocentesis. Read More
J Cardiol Cases 2015 Jun 24;11(6):155-157. Epub 2015 Mar 24.
Department of Cardiology, Uwajima City Hospital, Uwajima, Ehime, Japan.
An 84-year-old woman was urgently referred to our hospital owing to persistent malaise and chest pain. Takotsubo cardiomyopathy was diagnosed following transthoracic echocardiography, emergency coronary angiography, and left ventriculography. A left ventricular pressure tracing during cardiac catheterization revealed a 72 mmHg-intraventricular pressure gradient (LVPG). Read More
J Cardiol Cases 2010 Oct 24;2(2):e83-e87. Epub 2010 May 24.
Kumamoto Saishunsou National Hospital, 2659 Suya, Kohshi 861-1196, Kumamoto, Japan.
A 79-year-old man presented to the emergency room because of chest pain on 3 successive mornings. An electrocardiogram (ECG) showed ST segment elevation in leads II, III, and aVF. Laboratory findings including cardiac enzymes, were within normal limits, except a positive result for the troponin T test. Read More
J Cardiol Cases 2010 Oct 7;2(2):e63-e66. Epub 2016 Jun 7.
Division of Cardiology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan.
The patient was a 74-year-old woman with angina pectoris, who had undergone percutaneous coronary intervention with stent placement in the right coronary artery on October 2, 2007. On November 12 of the same year, she suffered from paroxysmal atrial fibrillation. She was treated with pilsicainide hydrochloride administered by intravenous injection, which was followed by a sudden sinus standstill, with marked bradycardia and a shock state. Read More
J Cardiol Cases 2017 Jan 17;15(1):14-17. Epub 2016 Oct 17.
Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.
A 49-year-old woman was admitted to our hospital because of repeated loss of consciousness. On arrival, she was in cardiopulmonary arrest associated with arrhythmia of Torsades de pointes, and recovered from it after cardiopulmonary resuscitation and defibrillation. The administration of a β-blocker and amiodarone was initiated to prevent ventricular tachycardia. Read More
J Cardiol Cases 2010 Jun 15;1(3):e141-e143. Epub 2010 Mar 15.
Department of Cardiovascular Medicine, Miyoshi Central Hospital, 531 Higashisakeya, Miyoshi, Hiroshima 728-8502, Japan.
We report a rare female case of typical takotsubo cardiomyopathy at the first admission and recurrent takotsubo cardiomyopathy with a unique pattern of contraction at the second admission. The condition manifested as akinesis in the middle portion of the left ventricle and hyperkinesis of the apex and base. Our case indicates that recurrent takotsubo cardiomyopathy can appear as transient midventricular ballooning syndrome, but it remains to be determined whether both diseases have a tendency to coexist. Read More
Int J Heat Mass Transf 2016 Dec 28;103:133-153. Epub 2016 Jul 28.
Boiling and Two-Phase Flow Laboratory (BTPFL), School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN 47907, USA.
This study explores flow boiling pressure drop of FC-72 in a rectangular channel subjected to single-side and double-sided heating for vertical upflow, vertical downflow, and horizontal flow with positive inlet quality. Analysis of temporal records of pressure transducer signals is used to assess the influences of orientation, mass velocity, inlet quality, heat flux, and single-sided versus double-sided heating on magnitude of pressure drop oscillations, while fast Fourier transforms of the same records are used to capture dominant frequencies of oscillations. Time-averaged pressure drop results are also presented, with trends focusing on the competing influences of body force and flow inertia, and particular attention paid to the impact of vapor content at the test section inlet and the rate of vapor generation within the test section on pressure drop. Read More
Health Phys 2013 Sep;105(3):296-300
*Department of Nuclear Engineering, Texas A&M University, MS 3133, College Station, TX 77843.
The AGN-201M at Texas A&M University is a small research reactor designed to be simple and easy to use for educational purposes. To ensure radiological safety in the reactor facility, dose equivalent rate measurements were taken near the reactor and at the operating console at various power levels. These measurements were then linearly extrapolated for two postulated reactivity accidents: a reactor pulse and a slow power transient. Read More
J Nucl Cardiol 2018 Dec 13. Epub 2018 Dec 13.
Nuclear Medicine Unit, Department of Experimental and Clinical Biomedical Sciences, University of Florence, Largo Brambilla 3, 50134, Florence, Italy.
Plant Reprod 2018 Dec 13. Epub 2018 Dec 13.
State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan, 430072, China.
Plant zygotes usually undergo asymmetrical cell division, giving rise to the formation of two daughter cells with distinct developmental cell fate. The small apical cell will develop into the major part of embryo proper, whereas the larger basal cell will divide to form a transient suspensor. Thus, the apical and basal cell lineages are an excellent model to study cell fate determination in relation to zygote polarity. Read More
eNeurologicalSci 2018 Dec 22;13:46-48. Epub 2018 Nov 22.
Krankenanstalt Rudolfstiftung, Juchgasse 25, A-1030 Wien, Austria.
Takotsubo syndrome (TTS) is a transient transient left ventricular dysfunction, predominantly affecting elderly women and often preceded by emotional or physical stress. TTS may be the cause as well as the consequence of stroke. We report a 82-years old female with a history of long-standing untreated arterial hypertension who was hospitalized because of a left-sided tongue paralysis and dysarthria. Read More
Clin Transl Radiat Oncol 2019 Jan 17;14:51-58. Epub 2018 Nov 17.
Department of Urology, Nara Medical University, Japan.
Purpose: To investigate chronological changes in lower urinary tract symptoms (LUTS) in patients who received iodine-125 brachytherapy (BT) for prostate cancer.
Methods: We enrolled 706 patients who received BT. Of these, 265 (38%) received BT combined with external beam radiation therapy (EBRT). Read More
Sci Adv 2018 Dec 12;4(12):eaau9403. Epub 2018 Dec 12.
Department of Mathematics and naXys, Namur Institute for Complex Systems, University of Namur, rempart de la Vierge 8, B 5000 Namur, Belgium.
We analyze a collection of empirical networks in a wide spectrum of disciplines and show that strong non-normality is ubiquitous in network science. Dynamical processes evolving on non-normal networks exhibit a peculiar behavior, as initial small disturbances may undergo a transient phase and be strongly amplified in linearly stable systems. In addition, eigenvalues may become extremely sensible to noise and have a diminished physical meaning. Read More
Global Chall 2018 Nov 19;2(11):1800032. Epub 2018 Sep 19.
Department of Chemical and Biomolecular Engineering University of Maryland College Park MD 20742 USA.
Photocatalytic CO reduction with water to hydrocarbons represents a viable and sustainable process toward greenhouse gas reduction and fuel/chemical production. Development of more efficient catalysts is the key to mitigate the limits in photocatalytic processes. Here, a novel ultrathin-film photocatalytic light absorber (UFPLA) with TiO films to design efficient photocatalytic CO conversion processes is created. Read More
Front Microbiol 2018 27;9:2792. Epub 2018 Nov 27.
Department of Biology, University of Konstanz, Konstanz, Germany.
Sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose) is produced by plants and other phototrophs and its biodegradation is a relevant component of the biogeochemical carbon and sulfur cycles. SQ is known to be degraded by aerobic bacterial consortia in two tiers via C-organosulfonates as transient intermediates to CO, water and sulfate. In this study, we present a first laboratory model for anaerobic degradation of SQ by bacterial consortia in two tiers to acetate and hydrogen sulfide (HS). Read More
Front Pharmacol 2018 28;9:1369. Epub 2018 Nov 28.
Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
G protein coupled receptors (GPCRs) were first characterized as signal transducers that elicit downstream effects through modulation of guanine (G) nucleotide-binding proteins. The pharmacotherapeutic exploitation of this signaling paradigm has created a drug-based field covering nearly 50% of the current pharmacopeia. Since the groundbreaking discoveries of the late 1990s to the present day, it is now clear however that GPCRs can also generate productive signaling cascades through the modulation of β-arrestin functionality. Read More
J Appl Crystallogr 2018 Dec 11;51(Pt 6):1511-1524. Epub 2018 Oct 11.
ESRF - The European Synchrotron, 38043 Grenoble, France.
This article presents the main technical features and performance of the upgraded beamline ID02 at the ESRF. The beamline combines different small-angle X-ray scattering techniques in one unique instrument, enabling static and kinetic investigations from ångström to micrometre size scales and time resolution down to the sub-millisecond range. The main component of the instrument is an evacuated detector tube of length 34 m and diameter 2 m. Read More
Nat Rev Cardiol 2018 Dec 13. Epub 2018 Dec 13.
CVPath Institute, Gaithersburg, MD, USA.
Fully bioresorbable scaffolds (BRS) were designed to overcome the limitations of metallic drug-eluting stents, which permanently cage the vessel wall, thereby preventing normal coronary vasomotion, preclude bypass grafting and can provoke long-term foreign-body responses. Although multiple scaffolds have been or are in development, the Absorb Bioresorbable Vascular Scaffold (BVS; Abbott Vascular) was the first FDA-approved device and was widely expected to fulfil the dream of interventional cardiologists of a transient scaffold that would disappear 'when the job was done' and would not hamper further treatment options. Although early, small studies and even large, randomized trials showed beneficial outcomes up to 1 year of follow-up, longer-term results have been disappointing, with increased rates of device thrombosis and target-lesion revascularization. Read More