220 results match your criteria Transient Acantholytic Dermatosis


Monolateral Grover's Disease with Blaschkoid Distribution.

Acta Dermatovenerol Croat 2017 Dec;25(4):31-311

Nicola di Meo, MD, Dermatology Department, University of Trieste, Ospedale Maggiore di Trieste, Piazza Ospedale 1, IV Piano Palazzina Infettivi, 34100 Trieste, Italy;

Dear Editor, Grover's disease, also known as transient acantholytic dermatosis, is an idiopathic and acquired pruritic eruption of small vesicles and erythematous papules, classically on the central chest. The pathogenesis is not clearly defined, although heat sweating and occlusion have been interpreted as predisposing factors. We describe a case of monolateral acantholytic eruption with blaschkoid distribution in a patient treated with an orthopedic bandage for a shoulder injury. Read More

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December 2017
3 Reads

Suprabasal acantholytic dermatologic toxicities associated checkpoint inhibitor therapy: A spectrum of immune reactions from paraneoplastic pemphigus-like to Grover-like lesions.

J Cutan Pathol 2018 Oct 24;45(10):764-773. Epub 2018 Jul 24.

Section of Dermatopathology, Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas.

Checkpoint inhibitors (CPIs) restore the function of effector immunocytes to target and destroy cancer cells. Immune-related adverse events (irAEs) are a consequence of immune reactivation, with unpredictable inflammatory response, loss of self-tolerance, and development of autoimmunity. Adverse events from CPIs that present as dermatologic toxicities have diverse clinical and histopathologic features. Read More

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http://dx.doi.org/10.1111/cup.13312DOI Listing
October 2018
29 Reads

Clinico-Pathological Study of 4 Cases of Pseudoherpetic Grover Disease: The Same as Vesicular Grover Disease.

Am J Dermatopathol 2018 Jun;40(6):445-448

Departments of Dermatology, and.

Introduction: Grover disease (GD) was described with 4 histopathological patterns, but later wide histopathological studies found additional ones including vesicular GD. From 2014, 2 new patterns, GD with epidermolytic hyperkeratosis and pseudoherpetic GD, have been proposed.

Objectives: The authors present 4 cases of pseudoherpetic GD and review the 6 previously published cases to better characterize this variant clinically and histopathologically. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001058DOI Listing
June 2018
24 Reads

Primary cutaneous follicle center lymphoma mimicking folliculitis.

Cutis 2018 Jan;101(1):E30-E33

Department of Dermatology, University of Texas MD Anderson Cancer Center, Houston, and Department of Dermatology, University of Texas Medical School, Houston, USA.

Primary cutaneous follicle center lymphoma (PCFCL) is the most common type of cutaneous B-cell lymphoma. The cutaneous manifestations of PCFCL typically include solitary erythematous or violaceous plaques, nodules, or tumors of varying sizes. Grouped lesions also may be observed, but multifocal disease is rare. Read More

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January 2018
19 Reads

Grover Disease With Epidermal Dysmaturation Pattern: A Common Histopathologic Finding.

Am J Dermatopathol 2018 Sep;40(9):642-646

Department of Pathology, Wake Forest University, School of Medicine, Medical Center Boulevard, Winston Salem, NC.

Background: Grover disease is an entity whose diagnosis is based on clinicopathologic correlation. Histopathologically, focal acantholysis is the most common finding. In some cases, there is prominent squamous atypia which can prove to be very challenging and the lesion may be confused with an epidermal neoplasm. Read More

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http://Insights.ovid.com/crossref?an=00000372-201809000-0000
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http://dx.doi.org/10.1097/DAD.0000000000001112DOI Listing
September 2018
7 Reads

Role of Immune Status in Chemotherapy-Induced Transient Acantholytic Dermatosis.

Skinmed 2017 1;15(6):483-484. Epub 2017 Dec 1.

Section of Dermatology, Department of Medicine, University of Chicago, Pritzker School of Medicine; Chicago, IL;

A 79-year-old man with a recent diagnosis of acute myeloblastic leukemia received induction chemotherapy with daunorubicin and cytarabine, plus moxifloxacin and fluconazole prophylaxis. Approximately 2 weeks later, an asymptomatic eruption appeared on his trunk. He then developed a neutropenic fever and was started on aztreonam, vancomycin, voriconazole, and amikacin and was transferred to our facility from an outside hospital. Read More

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December 2017
4 Reads

Dermoscopic characteristics of transient acantholytic dermatosis (Grover's disease).

Eur J Dermatol 2017 12;27(6):648-650

Department of Dermatology, Venerology, and Allergology; University Medical Center, Ruprecht-Karl University, Heidelberg, Germany.

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http://dx.doi.org/10.1684/ejd.2017.3104DOI Listing
December 2017
9 Reads

Stellate erosion: the dermoscopic Nikolsky sign?

Eur J Dermatol 2017 12;27(6):659-660

First Dermatology Department, Aristotle University of Thessaloniki, Delfon 124, 54643, Thessaloniki, Greece.

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http://dx.doi.org/10.1684/ejd.2017.3114DOI Listing
December 2017
3 Reads

Grover's disease: dermoscopy, reflectance confocal microscopy and histopathological correlation.

Dermatol Pract Concept 2017 Jul 31;7(3):51-54. Epub 2017 Jul 31.

Dermatology Clinic, University of Catania, Italy.

Grover's disease is a benign condition of unknown origin characterized clinically by an erythematous papulovesicular eruption and histopathologically by intraepidermal clefting and four different patterns of acantholysis: Darier-like, pemphigus-like, spongiotic, and Hailey-Hailey-like. A case of a 54-year-old female affected by Grover's disease and showing a Darier-like histopathological pattern is described. Polarized light dermoscopy (PLD) revealed the presence of polygonal, star-like shaped yellowish/brownish areas of various sizes surrounded by a thin whitish halo. Read More

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http://dx.doi.org/10.5826/dpc.0703a11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5661164PMC
July 2017
8 Reads

Pruritic eruption on the chest.

Cutis 2017 Aug;100(2):84;94;96

Department of Dermatology, Department of Pathology, Saint Louis University School of Medicine, Missouri, USA.

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August 2017
4 Reads

Atypical features and systemic associations in extensive cases of Grover disease: A systematic review.

J Am Acad Dermatol 2017 Nov 14;77(5):952-957.e1. Epub 2017 Sep 14.

Department of Pathology, University of California, San Francisco, California. Electronic address:

Background: Grover disease is an acantholytic disorder that typically occurs on the trunk of older individuals, primarily white men, in association with heat and xerosis. Cases with extensive and/or atypical distributions have been reported.

Objective: To review the literature characterizing the population, morphology, associations, and disease course of extensive or atypical eruptions of Grover disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622173194
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http://dx.doi.org/10.1016/j.jaad.2017.06.041DOI Listing
November 2017
9 Reads

Grover's disease in a patient with pemphigus vulgaris.

Int J Dermatol 2017 Oct 2;56(10):1052-1054. Epub 2017 Aug 2.

Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Kurume, Fukuoka, Japan.

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http://dx.doi.org/10.1111/ijd.13718DOI Listing
October 2017
8 Reads

Chronic inflammatory acantholytic dermatosis: a previously under-recognized or emerging variant of Grover disease.

Clin Exp Dermatol 2017 Aug 21;42(6):683-685. Epub 2017 Jun 21.

Dermatology Department, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Kent Lodge, Thomas Drive, Liverpool, L14 3LB, UK.

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http://dx.doi.org/10.1111/ced.13169DOI Listing
August 2017
3 Reads

Histopathological aspects of cutaneous erythematous-papular eruptions induced by immune checkpoint inhibitors for the treatment of metastatic melanoma.

Int J Dermatol 2017 May 10;56(5):527-533. Epub 2017 Feb 10.

Oncodermatology department, CIC, CHU, Nantes, France.

Background: Immune checkpoint blockade therapy (ICBT) for the treatment of melanoma has led to an important improvement of overall survival in advanced stage patients. However, secondary cutaneous maculopapular eruptions (CMPEs) are frequent and remain poorly characterized.

Methods: We performed a retrospective analysis of melanoma patients from our institution who developed CMPEs during ICBT. Read More

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http://dx.doi.org/10.1111/ijd.13540DOI Listing
May 2017
22 Reads

Erratum to: A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

J Immunother Cancer 2017 18;5. Epub 2017 Jan 18.

Department of Melanoma Medical Oncology, University of Texas-MD Anderson Cancer Center, Houston, TX USA.

[This corrects the article DOI: 10.1186/s40425-016-0157-6.]. Read More

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http://dx.doi.org/10.1186/s40425-017-0208-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244590PMC
January 2017
9 Reads

Pseudoherpetic transient acantholytic dermatosis (Grover disease): case series and review of the literature.

Authors:
Kiran Motaparthi

J Cutan Pathol 2017 May 16;44(5):486-489. Epub 2017 Feb 16.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

A total of 3 cases of pseudoherpetic transient acantholytic dermatosis (Grover disease) are presented, followed by a brief review of prior reports. All 3 patients were above the age of 60 and presented with a pruritic eruption composed of papules with or without vesicles distributed on the trunk. For all 3 patients, the clinical differential diagnosis included drug eruption but did not include Grover disease; in 1 patient, the clinical impression included herpesvirus infection. Read More

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http://dx.doi.org/10.1111/cup.12909DOI Listing
May 2017
3 Reads

Dermoscopy of Grover disease.

J Am Acad Dermatol 2017 Feb;76(2S1):S60-S63

Dermatology Unit, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1016/j.jaad.2016.07.031DOI Listing
February 2017
6 Reads

Sudden Onset of an Itchy Papular Eruption: A Quiz.

Acta Derm Venereol 2017 05;97(5):667-668

Department of Dermatology, Center for Chronic Pruritus, University Hospital Münster, Münster, Germany.

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http://dx.doi.org/10.2340/00015555-2588DOI Listing
May 2017
19 Reads

A case report of Grover's disease from immunotherapy-a skin toxicity induced by inhibition of CTLA-4 but not PD-1.

J Immunother Cancer 2016 20;4:55. Epub 2016 Sep 20.

Department of Melanoma Medical Oncology, University of Texas-MD Anderson Cancer Center, Houston, TX USA.

Background: Immune related adverse events (irAEs) are common side effects of checkpoint inhibitory (CPI) therapies targeting CTLA-4 and PD-1/PD-L1. Grover's disease is an uncommon dermatologic condition with unclear pathogenesis previously reported as an irAE with ipilimumab.

Case Presentation: We report an additional case of ipilimumab-induced Grover's disease. Read More

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http://dx.doi.org/10.1186/s40425-016-0157-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028978PMC
September 2016
12 Reads

Paraneoplastic Itch Management.

Curr Probl Dermatol 2016 23;50:149-54. Epub 2016 Aug 23.

Paraneoplastic itch occurs as the result of a systemic reaction to an underlying malignancy. Paraneoplastic itch is most commonly associated with lymphoproliferative malignancies and solid tumors that result in cholestasis. Paraneoplastic itch may occur in the absence of a primary rash or in association with dermatologic conditions such as erythroderma, acanthosis nigricans, dermatomyositis, Grover's disease, and eruptive seborrheic keratosis. Read More

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https://www.karger.com/Article/FullText/446060
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http://dx.doi.org/10.1159/000446060DOI Listing
April 2017
20 Reads

Grover's-like drug eruption in a patient with metastatic melanoma under ipilimumab therapy.

J Immunother Cancer 2016 16;4:47. Epub 2016 Aug 16.

Cantonal Hospital Baselland, Institute of Pathology, Mühlemattstrasse 11, CH-4410 Liestal, Switzerland.

Background: Dermatologic toxicity is an important adverse effect of immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and programmed cell death 1 receptor (PD-1) or PD ligand 1 (PD-L1). Skin toxicity most commonly includes a maculopapular erythematous rash and pruritus. Rarely life threatening complications such as Steven's Johnson syndrome or toxic epidermal necrolysis may occur. Read More

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http://dx.doi.org/10.1186/s40425-016-0151-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986338PMC
August 2016
2 Reads

Transient acantholytic dyskeratosis (Grover's disease) after bone marrow transplantation.

Australas J Dermatol 2016 Nov 30;57(4):e120-e122. Epub 2016 Jun 30.

Westmead Hospital, Sydney, New South Wales, Australia.

Cutaneous eruptions in recipients of allogeneic haematopoietic stem cell transplantation (AHSCT) are frequent, and common aetiologies include graft-versus-host disease (GVHD), drug reactions, viral infections and engraftment syndrome. Transient acantholytic dermatosis or Grover's disease has been described in oncology patients and it is rarely reported after AHSCT. However, this benign and self-limiting condition should be histologically distinguished from other, more serious entities, mainly stage IV GVHD, in order to avoid inappropriate treatment with corticosteroids and intensive immunosuppression. Read More

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http://dx.doi.org/10.1111/ajd.12517DOI Listing
November 2016
11 Reads

Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15-year analysis of dermatopathologic data.

Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.

Temple University School of Medicine, Philadelphia, PA, USA.

Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.

Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.

Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More

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http://dx.doi.org/10.1111/ijd.13229DOI Listing
October 2016
31 Reads

Dermoscopy of Grover's disease: Variability according to histological subtype.

J Dermatol 2016 Aug 19;43(8):937-9. Epub 2016 Feb 19.

Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.

Distinguishing Grover's disease from other papular dermatoses is often a troublesome task. According to two relatively recent case reports, dermoscopy may be useful in assisting the diagnosis of such a disorder by showing a peculiar pattern. The aim of this study was to evaluate the dermoscopic features of Grover's disease in a larger series of patients and correlate dermoscopy with histopathological findings. Read More

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http://dx.doi.org/10.1111/1346-8138.13298DOI Listing
August 2016
6 Reads

Dermoscopic features of a case of transient acantholytic dermatosis.

Australas J Dermatol 2017 Feb 14;58(1):50-52. Epub 2016 Jan 14.

Department of Dermatology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan.

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http://dx.doi.org/10.1111/ajd.12434DOI Listing
February 2017
5 Reads

Grover's disease in chronic kidney failure.

Nefrologia 2015 17;35(3):331-4. Epub 2015 Jun 17.

Servicio de Anatomía Patológica, Complejo Hospitalario Universitario de Ferrol, Ferrol, A Coruña, España.

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http://dx.doi.org/10.1016/j.nefro.2015.05.009DOI Listing
April 2017
6 Reads

Grover's disease and cutaneous melanoma: a fortuitous association or a paraneoplastic case?

G Ital Dermatol Venereol 2015 Dec 10;150(6):756-8. Epub 2015 Jul 10.

Dermatology Unit, Department of Clinical Medicine and Immunologic Science, University of Siena, "Le Scotte" Hospital, Siena, Italy -

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December 2015
3 Reads

Pruritic Papules Following Lumbar Corset Use: A Quiz. Grover's disease.

Acta Derm Venereol 2015 Jul;95(6):762-3

Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.2340/00015555-2071DOI Listing
July 2015
12 Reads

Grover's Disease with Acrosyringeal Acantholysis: A Rare Histological Presentation of an Uncommon Disease.

Indian J Dermatol 2014 Nov;59(6):621-3

Department of Dermatology, Apollo Gleneagles Hospital, Kolkata, West Bengal, India. E-mail:

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http://dx.doi.org/10.4103/0019-5154.143548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248512PMC
November 2014
20 Reads

[Acantholytic dermatosis in patients treated by vemurafenib: 2 cases].

Ann Dermatol Venereol 2014 Nov 23;141(11):689-93. Epub 2014 Oct 23.

Clinique de dermatologie et photobiologie, hôpital Nord, CHU de Grenoble, Cs 10217, boulevard de la-Chantourne-La-Tronche, 38043 Grenoble cedex 9, France.

Background: Acantholytic dyskeratosis under BRAF inhibitors are dermatological diseases rarely reported to date.

Patients And Methods: We report 2 cases of acantholytic dyskeratosis, reaching the trunk and the seborrheic zones, not itchy, appeared one month after the introduction of vemurafenib. The histological analysis was typical of a "Grover-like rash" for the 2 patients. Read More

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http://dx.doi.org/10.1016/j.annder.2014.09.024DOI Listing
November 2014
4 Reads

Epidermal multinucleated giant cells are not always a histopathologic clue to a herpes virus infection: multinucleated epithelial giant cells in the epidermis of lesional skin biopsies from patients with acantholytic dermatoses can histologically mimic a herpes virus infection.

Dermatol Pract Concept 2014 Oct 31;4(4):21-7. Epub 2014 Oct 31.

Division of Dermatology, University of California San Diego, San Diego, California.

Background: Multinucleated giant cells in the epidermis can either be epithelial or histiocytic. Epithelial multinucleated giant cells are most often associated with herpes virus infections.

Purpose: To review the histologic differential diagnosis of conditions with epithelial and histiocytic multinucleated giant cells-since multinucleated giant cells in the epidermis are not always pathognomonic of a cutaneous herpes virus infection-and to summarize dermatoses in which herpes virus infection has been observed to coexist. Read More

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http://dx.doi.org/10.5826/dpc.0404a03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4230253PMC
October 2014
13 Reads

Pruritic eruption on the chest.

J Fam Pract 2014 Nov;63(11):677-9

Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia. Email:

The fact that this patient's rash was limited to his chest provided an important diagnostic clue. Read More

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November 2014
8 Reads

Cutaneous crystal storing histiocytosis: a report of two cases.

J Cutan Pathol 2015 Feb 24;42(2):136-43. Epub 2014 Nov 24.

Department of Anatomical Pathology, Liverpool Hospital, Liverpool, Australia.

Crystal storing histiocytosis (CSH) is a rare condition where crystals accumulate in the cytoplasm of macrophages and is usually associated with a lymphoplasmacytic neoplasm producing a monoclonal immunoglobulin with kappa light chain. CSH with primary manifestation in the skin is extraordinarily rare and limited to four case reports in the literature. Here we present two cases of cutaneous CSH. Read More

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http://dx.doi.org/10.1111/cup.12413DOI Listing
February 2015
3 Reads

[Papular rash under the breasts: is it persistent zoster? Grover disease].

MMW Fortschr Med 2014 Apr;156(6):5, 43

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April 2014
7 Reads

First report of ipilimumab-induced Grover disease.

Br J Dermatol 2014 Nov 24;171(5):1236-7. Epub 2014 Sep 24.

Department of Dermatology, University Hospital of Montpellier, University Montpellier 1, 80 rue Augustin Fliche, F-34295, Montpellier Cedex 5, France.

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http://doi.wiley.com/10.1111/bjd.13058
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http://dx.doi.org/10.1111/bjd.13058DOI Listing
November 2014
4 Reads

Grover's Disease in a Liver Transplant Patient.

Ann Dermatol 2014 Feb 17;26(1):117-8. Epub 2014 Feb 17.

Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.5021/ad.2014.26.1.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956779PMC
February 2014
6 Reads

Malassezia skin diseases in humans.

G Ital Dermatol Venereol 2013 Dec;148(6):609-19

Division of Dermatology Department of Surgery and Translational Medicine University of Florence, Florence, Italy -

Although Malassezia yeasts are a part of the normal microflora, under certain conditions they can cause superficial skin infection, such as pityriasis versicolor (PV) and Malassezia folliculitis. Moreover the yeasts of the genus Malassezia have been associated with seborrheic dermatitis and dandruff, atopic dermatitis, psoriasis, and, less commonly, with confluent and reticulated papillomatosis, onychomycosis, and transient acantholytic dermatosis. The study of the clinical role of Malassezia species has been surrounded by controversy due to the relative difficulty in isolation, cultivation, and identification. Read More

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December 2013
6 Reads

Zosteriform transient acantholytic dermatosis.

J Dermatol 2014 Jan 20;41(1):104-5. Epub 2013 Dec 20.

Department of Dermatology, Seoul St Mary's Hospital, College of Medicine, Catholic University of Korea, Seoul, Korea.

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http://dx.doi.org/10.1111/1346-8138.12320DOI Listing
January 2014
4 Reads

Pruritus in the older patient: a clinical review.

JAMA 2013 Dec;310(22):2443-50

Department of Dermatology, University of California, San Francisco.

Importance: Pruritus is a common problem among elderly people and, when severe, causes as much discomfort as chronic pain. Little evidence supports pruritus treatment, limiting therapeutic possibilities and resulting in challenging management problems.

Objectives: To present the evidence on the etiology, diagnosis, and treatment of pruritus in the elderly and, using the best available evidence, provide an approach for generalist physicians caring for older patients with pruritus. Read More

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http://dx.doi.org/10.1001/jama.2013.282023DOI Listing
December 2013
4 Reads

Grover disease (transient acantholytic dermatosis) in acute myeloid leukemia on FDG PET/CT.

Clin Nucl Med 2014 Feb;39(2):e173-5

From the Departments of *Radiology, and †Pathology, University of Arkansas for Medical Sciences, Little Rock, AR.

A 48-year-old man with a newly diagnosed acute myeloid leukemia developed purpuric rash on day 6 after chemotherapy. Skin biopsy on day 8 demonstrated Grover disease. Triamcinolone treatment started on day 10 with subjective improvement on day 15. Read More

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http://dx.doi.org/10.1097/RLU.0000000000000252DOI Listing
February 2014
4 Reads

Is Grover's disease an autoimmune dermatosis?

Exp Dermatol 2013 Dec;22(12):781-4

Department of Dermatology, University of California, Irvine, CA, USA.

Grover's disease (GD) is a transient or persistent, monomorphous, papulovesicular, asymptomatic or pruritic eruption classified as non-familial acantholytic disorder. Contribution of autoimmune mechanisms to GD pathogenesis remains controversial. The purpose of this study was to investigate antibody-mediated autoimmunity in 11 patients with GD, 4 of which were positive for IgA and/or IgG antikeratinocyte antibodies by indirect immunofluorescence. Read More

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http://dx.doi.org/10.1111/exd.12266DOI Listing
December 2013
34 Reads

[Case no. 4. Bullous dermatosis].

Authors:
Janine Wechsler

Ann Pathol 2013 Jun 31;33(3):193-5. Epub 2013 May 31.

Département de pathologie, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.

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http://dx.doi.org/10.1016/j.annpat.2013.04.012DOI Listing
June 2013
11 Reads

Transient acantholytic dermatosis (Grover's disease) with an isolated eruption.

Eur J Dermatol 2013 May-Jun;23(3):424-5

Department of Dermatology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan.

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http://dx.doi.org/10.1684/ejd.2013.2031DOI Listing
November 2015
4 Reads

Pseudoherpetic grover disease: report of 2 cases and review of the literature.

Am J Dermatopathol 2014 Sep;36(9):746-50

*College of Human Medicine, Michigan State University, Grand Rapids, MI; Departments of †Dermatopathology, ‡Dermatology, and §Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, MA; ¶Harvard Combined Dermatology Residency Training Program, Boston, MA; and ‖Department of Pathology, Brigham and Women's Hospital/Harvard Medical School, Boston, MA.

Two cases of a pseudoherpetic variant of Grover disease are presented. The first patient was a 60-year-old woman who had high fevers in combination with right lower lobe pneumonia. She developed an itchy papulovesicular rash on her back and upper abdomen. Read More

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http://dx.doi.org/10.1097/DAD.0b013e31828b10c1DOI Listing
September 2014
3 Reads

Grover disease with features of epidermolytic hyperkeratosis.

Am J Dermatopathol 2014 Apr;36(4):358-9

Department of Dermatology, University of Texas Southwestern Medical School, Dallas, Texas Dermpath Diagnostics Cockerell and Associates, Dallas, Texas Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1097/DAD.0b013e318282247dDOI Listing
April 2014
3 Reads

Grover's Disease after Heart Transplantation: A Case Report.

Case Rep Transplant 2012 20;2012:126592. Epub 2012 Dec 20.

Division of Cardiac Surgery, IRCCS San Matteo Hospital Foundation, University of Pavia School of Medicine, 27100 Pavia, Italy ; U.O. Medicina Interna, Policlinico di Monza, Monza, Italy.

Grover's disease is a transient acantholytic dermatosis of unknown cause, manifesting clinically as a papular skin eruption that is usually located on the anterior chest and abdomen. Histologically characterized by an acantholytic pattern, it has been associated with numerous disorders, including hematologic malignancies, chronic renal failure, and HIV infection, as well as with chemotherapy and bone marrow and/or kidney transplant. Evaluation of followup and treatment is often complicated by spontaneous remission and the occasionally fluctuant course of the disease. Read More

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http://dx.doi.org/10.1155/2012/126592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3539346PMC
January 2013
2 Reads

Cutaneous toxicities of RAF inhibitors.

Lancet Oncol 2013 Jan;14(1):e11-8

Department of Dermatology, Westmead Hospital, Sydney, NSW, Australia.

The RAF inhibitors vemurafenib and dabrafenib are emerging as the standard of care for Val600 BRAF-mutant metastatic melanoma. These drugs have shown clinical benefit over the standard care (dacarbazine); however, they are associated with frequent cutaneous adverse events, which can be concerning to the patient and their physician. Herein, we review the range of cutaneous disorders that seem to be induced by RAF inhibitors, including cutaneous squamous-cell carcinoma, hyperkeratotic lesions, Grover's disease, keratosis pilaris-like reactions, and photosensitivity. Read More

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Source
https://linkinghub.elsevier.com/retrieve/pii/S14702045127041
Publisher Site
http://dx.doi.org/10.1016/S1470-2045(12)70413-8DOI Listing
January 2013
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