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J Voice 2018 Oct 16. Epub 2018 Oct 16.

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA. Electronic address:

Vocal fold movement impairment may significantly compromise postoperative recovery and quality of life of patients following thoracic or cardiothoracic surgery or prolonged intubation. The literature is limited and there is no standard screening protocol for the optimal postoperative swallowing and aspiration evaluations. We performed retrospective review of adult patients undergoing early vocal fold (VF) injection laryngoplasty for acute postoperative Vocal fold movement impairment (<30 days) that had both pre- and postinjection speech language pathologist (SLP) performed swallowing/aspiration evaluations. Read More

Acta Otorhinolaryngol Ital 2017 Oct;37(5):444-446

Department of Otolaryngology, Head & Neck Surgery, American University of Beirut Medical Center, Beirut- Lebanon.

Injection laryngoplasty has gained popularity as a treatment modality for glottal insufficiency. Several approaches have been described, specifically transcutaneous, transoral and transnasal. The authors describe a novel technique performed successfully on three subjects, namely endoscopic injection laryngoplasty using the modified Guedel oral airway. Read More

Laryngoscope 2016 Apr 25;126(4):936-40. Epub 2015 Sep 25.

Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University Hospital, Busan, Korea.

Objectives/hypothesis: Vocal fold injection is a minimally invasive technique for various vocal fold pathologies. The shortcomings of the cricothyroid (CT) membrane approach are mainly related to invisibility of the injection needle. If localization of the needle tip can be improved during vocal fold injection with the CT approach, the current problems of the technique can be overcome. Read More

J Laryngol Otol 2012 Mar 6;126(3):260-6. Epub 2011 Oct 6.

Department of Otorhinolaryngology - Head and Neck Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea.

Objectives: This study aimed to analyse demographic profiles and pre-injection stroboscopic findings for patients with unilateral vocal fold paralysis, to investigate possible predictive factors for voice outcomes of injection laryngoplasty.

Materials And Methods: Fifty-nine unilateral vocal fold paralysis patients underwent vocal fold augmentation, using transcutaneous Artecoll (polymethyl methacrylate microspheres plus bovine collagen) injection into the paralysed vocal fold via the cricothyroid space. Three months later, patients were divided into improved (n = 44) and unimproved (n = 15) groups, using the perceptual grade-roughness-breathiness-asthenia-strain scale, and their clinical characteristics and pre-operative stroboscopic findings compared. Read More

J Voice 2010 Jan 16;24(1):113-8. Epub 2009 Jun 16.

Department of Otolaryngology, Singapore General Hospital, Singapore.

The objective was to determine if particle size affects durability of medialization in patients undergoing injection laryngoplasty (IL) with hyaluronic acid (HA) for unilateral vocal cord paralysis (UVCP). We hypothesized that large particle-size HA (LPHA) persists longer after injection to produce a more durable vocal result. The study design used was a prospective randomized controlled single-blind trial. Read More

Eur Arch Otorhinolaryngol 2008 Mar 25;265(3):313-9. Epub 2007 Sep 25.

Department of Otolaryngology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 108, Pyoung-Dong, Jongro-Ku, 110-746 Seoul, South Korea.

A variety of approaches have been introduced to perform injection laryngoplasty under local anesthesia. Among these reported methods, transcutaneous injection through the cricothyroid space offers many advantages, but it possesses some technical difficulties during access to the vocal fold. The aim of this study was to assess the anatomic references related to transcutaneous injection laryngoplasty through cricothyroid space using 3-dimensionally reconstructed computed tomography to provide guidelines and to achieve higher efficacy during the procedure. Read More

J Voice 2003 Dec;17(4):589-95

University of Miami School of Medicine, The Department of Otolaryngology, Miami, Florida 33101, USA.

Medialization thyroplasty (type I) has become the gold standard to improve glottic closure due to unilateral vocal fold paralysis. A newer injection method utilizing homologous collagen from cadaveric human tissue has been described as an attractive alternative as no donor site is required, there is a very low risk of hypersensitivity, and the intact, acellular collagen fibers may suffer a reduced long-term reabsorption rate. Preliminary results on eight patients comparing presurgical and postsurgical parameters (perceptual, stroboscopic, acoustic, and aerodynamic) revealed comparable results when compared with a control group of individuals, age- and sex-matched, that had undergone standard medialization thyroplasty (type I). Read More