11,358 results match your criteria Transcutaneous Electrical Nerve Stimulation

Noninvasive Transcutaneous Auricular Vagal Nerve Stimulation Improves Gastric Slow Waves Impaired by Cold Stress in Healthy Subjects.

Neuromodulation 2022 May 18. Epub 2022 May 18.

Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, MI, USA. Electronic address:

Background/aims: Stress is known to inhibit gastric motility. The aim of this study was to investigate the effects and autonomic mechanisms of transcutaneous auricular vagal nerve stimulation (taVNS) on cold stress (CS)-induced impairment in gastric motility that are relevant to the brain-gut interactions in healthy volunteers.

Materials And Methods: Healthy volunteers (eight women; age 28. Read More

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Effect of Early Electroacupuncture Combined with Enhanced Recovery after Surgery (ERAS) on Pain Perception and Dysfunction in Patients after Total Knee Arthroplasty (TKA).

Biomed Res Int 2022 9;2022:6560816. Epub 2022 May 9.

Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, China.

Objective: A retrospective case-control study was performed to observe the effect and clinical significance of early electroacupuncture combined with enhanced recovery after surgery (ERAS) on pain perception and dysfunction after total knee arthroplasty (TKA).

Methods: About 100 patients who diagnosed with TKA from February 2019 to April 2021 were enrolled in our hospital. The patients were arbitrarily assigned into control group and study group. Read More

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Effective-Component Compatibility of Bufei Yishen Formula III Combined with Electroacupuncture Suppresses Inflammatory Response in Rats with Chronic Obstructive Pulmonary Disease via Regulating SIRT1/NF-B Signaling.

Biomed Res Int 2022 9;2022:3360771. Epub 2022 May 9.

Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.

Objective: To explore more efficient treatments for chronic obstructive pulmonary disease (COPD), effective-component compatibility of Bufei Yishen formula III (ECC-BYF III) and electroacupuncture were tested on rats with COPD, and silent information regulator transcript-1 (SIRT1)/nuclear factor-kappaB (NF-B) signaling was further investigated to interpret the therapy.

Methods: In total, 70 rats were randomly divided into control (Control), model (Model), aminophylline (APL), ECC-BYF III, electroacupuncture (EA), ECC-BYF III+EA, and sham electroacupuncture (SA) groups. Cigarette smoke exposure combined with repeated bacterial infections was used to establish COPD models in 1-12 weeks. Read More

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Identifying Oscillations under Multi-site Sensory Stimulation for High-level Peripheral Nerve Injured Patients:A Pilot Study.

J Neural Eng 2022 May 17. Epub 2022 May 17.

Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences, 1068 Xueyuan Boulevard, University Town of Shenzhen, Xili Nanshan, Shenzhen 518055, China, Shenzhen, Guangdong, 518055, CHINA.

Objective: For high-level peripheral nerve injured (PNI) patients with severe sensory dysfunction of upper extremities, identifying the multi-site tactile stimulation is of great importance to provide neurorehabilitation with sensory feedback. In this pilot study, we showed the feasibility of identifying multi-site and multi-intensity tactile stimulation in terms of electroencephalography (EEG).

Approach: Three high-level PNI patients and eight non-PNI participants were recruited in this study. Read More

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An assessment of sensory sensitivity in women suffering from depression using transcutaneous electrical nerve stimulation.

PeerJ 2022 9;10:e13373. Epub 2022 May 9.

Józef Babiński Clinical Hospital in Krakow, Psychiatric Ward, Kraków, Poland.

Background: Perception is the process or result of the process arising from the mental interpretation of the phenomena occurring, therefore it depends not only on physiology, but is also psychologically and socially conditioned. The aim of this study was to assess if there is a difference in the sensory sensitivity to an electrical stimulus in women suffering from depression and what the hedonic rating is of the lived experience of transcutaneous electrical nerve stimulation.

Methods: The depression group: 44 women, who were inpatients treated for depression at the Psychiatric Ward in the Clinical Hospital, and the control group: 41 women, matched by the age, height and weight, with no mental illness. Read More

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Effects of neuromodulation on treatment of recurrent anal fissure: A systematic review.

Int J Surg 2022 May 11;102:106661. Epub 2022 May 11.

Colorectal Research Center, Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Background: Anal fissure is a linear tear in the distal anoderm most frequently occurring in the posterior midline. Lateral internal sphincterotomy is considered the gold standard for the treatment of this condition. To this date, several pharmacological and neuromodulatory therapies have been tried out as alternative non-invasive treatments for anal fissures, however, the efficacy of some of these methods remains to be understood. Read More

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Orofacial Pain: Molecular Mechanisms, Diagnosis, and Treatment 2021.

Yoshizo Matsuka

Int J Mol Sci 2022 Apr 27;23(9). Epub 2022 Apr 27.

Department of Stomatognathic Function and Occlusal Reconstruction, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto-cho, Tokushima 770-8504, Japan.

The Special Issue "Orofacial Pain: Molecular Mechanisms, Diagnosis, and Treatment 2021" contains 6 articles published by 41 authors from different countries focusing on nucleus accumbens core GABAergic neurons, receptor-interacting serine/threonine-protein kinase 1, pannexin 1-mediated ATP signaling, ultra-low-frequency transcutaneous electrical nerve stimulation, and triamcinolone acetonide. The content covers several pain models, including neuropathic pain caused by peripheral nerve constriction or malpositioned dental implants, tongue cancer, myogenous temporomandibular dysfunction, and oral ulcerative mucositis. In addition, a review paper on trigeminal neuralgia is included. Read More

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Effect of acupuncture on gut microbiota in participants with subjective cognitive decline.

Medicine (Baltimore) 2022 May 6;101(18):e27743. Epub 2022 May 6.

Department of Obstetrics and Gynecology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Abstract: A close relationship has recently been described between subjective cognitive decline (SCD) and gut microbiota disorders. Herein, we aim to investigate the effect of electroacupuncture (EA) on gut microbiota in participants with SCD.We conducted a study of 60 participants with SCD. Read More

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Auricular Transcutaneous Vagus Nerve Stimulation Acutely Modulates Brain Connectivity in Mice.

Front Cell Neurosci 2022 25;16:856855. Epub 2022 Apr 25.

Laboratory of Neuropharmacology, Department of Medicine and Life Sciences, Universitat Pompeu Fabra, Barcelona, Spain.

Brain electrical stimulation techniques take advantage of the intrinsic plasticity of the nervous system, opening a wide range of therapeutic applications. Vagus nerve stimulation (VNS) is an approved adjuvant for drug-resistant epilepsy and depression. Its non-invasive form, auricular transcutaneous VNS (atVNS), is under investigation for applications, including cognitive improvement. Read More

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Minimal handgrip force is needed for transcutaneous electrical stimulation to improve hand functions of patients with severe spinal cord injury.

Sci Rep 2022 May 11;12(1):7733. Epub 2022 May 11.

Neurosurgery Department, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

Spinal cord stimulation enhanced restoration of motor function following spinal cord injury (SCI) in unblinded studies. To determine whether training combined with transcutaneous electrical spinal cord stimulation (tSCS), with or without systemic serotonergic treatment with buspirone (busp), could improve hand function in individuals with severe hand paralysis following SCI, we assessed ten subjects in a double-blind, sham-controlled, crossover study. All treatments-busp, tSCS, and the busp plus tSCS-reduced muscle tone and spasm frequency. Read More

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Electroacupuncture in the treatment of neurogenic urine retention through autophagy mediated by AMPK/mTOR pathway.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Apr;47(4):488-496

Department of Massage, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193.

Objectives: Electroacupuncture can enhance autophagic flow, promote neuronal regeneration, axonal and myelin remodeling to achieve the protection of spinal cord injury, but its role in neurogenic urine retention is not completely clear. This study aims to investigate whether the mechanism of electroacupuncture in the treatment of neurogenic urine retention is through autophagy mediated by adenosine monophosphate activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) pathway.

Methods: A rat model of neurogenic urine retention after sacral spinal cord injury was established. Read More

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[Electroacupuncture at Siguan points for migraine of liver hyperactivity: a randomized controlled trial].

Zhongguo Zhen Jiu 2022 May;42(5):498-502

Department of Acupuncture and Moxibustion, Affiliated Longhua Hospital of Shanghai University of TCM, Shanghai 200032, China.

Objective: To compare the clinical effect of electroacupuncture at Siguan points and flunarizine hydrochloride capsule on migraine of liver hyperactivity.

Methods: A total of 110 patients with migraine of liver hyperactivity were randomly divided into an electroacupuncture group (55 cases, 2 cases dropped off) and a western medication group (55 cases, 2 cases dropped off). In the electroacupuncture group, electroacupuncture was applied at Siguan points (Hegu [LI 4] and Taichong [LR 3]), with disperse-dense wave of 2 Hz/100 Hz in frequency and current intensity of 0. Read More

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Evaluating hip disarticulation outcomes in a 51-patient series.

J Orthop 2022 May-Jun;31:117-120. Epub 2022 Apr 19.

Department of Plastic and Reconstructive Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, USA.

Background: Hip disarticulations are proximal lower extremity amputations with high postoperative complication and mortality rates. The purpose of the study was to evaluate hip disarticulation outcomes at our institution. Targeted Muscle Reinnervation (TMR) is an effective surgical technique shown to reduce pain in amputees. Read More

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Non-pharmacological integrative therapies for chronic cancer pain.

J Oncol Pharm Pract 2022 May 9:10781552221098437. Epub 2022 May 9.

24430West Anaheim Medical Center, CA, USA.

Objective: Chronic pain is one of the most detrimental symptoms exhibited by cancer patients, being an indication for opioid therapy in up to half of the patients' receiving chemotherapy and in 90% of advanced cases. Various successful non-pharmacological integrative therapy options have been explored and implemented to improve the quality of life in these patients. This review aims to highlight the mechanisms implicated; assessment tools used for cancer pain and summarize current evidence on non-pharmacological approaches in the treatment of chronic cancer pain. Read More

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Peripheral Nerve Stimulation for Chronic Pain and Migraine: A Review.

Phys Med Rehabil Clin N Am 2022 05;33(2):379-407

Department of Anesthesiology, Division of Pain Medicine, University of California, San Diego, CA, USA; Koman Family Outpatient Pavilion, Center for Pain Medicine, 9400 Campus Point Drive, MC 7328, La Jolla, CA 92037, USA.

Interventional pain procedures offer treatments for chronic pain conditions refractory to conservative measures. Neuromodulation, including peripheral nerve stimulation (PNS), applies electrical stimuli to neural structures to treat pain. Here we review the literature on PNS for various chronic pain conditions including neuropathic pain, postamputation pain, musculoskeletal pain, migraine, and pelvic pain. Read More

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Cardiac activity in walleye (Sander vitreus) during exposure to and recovery from chemical anaesthesia, electroanaesthesia, and electrostunning.

J Fish Biol 2022 May 4. Epub 2022 May 4.

Great Lakes Acoustic Telemetry Observation System, Department of Fisheries and Wildlife, Michigan State University, 1405 S. Harrison Rd., East Lansing, MI, USA.

Handling and conducting invasive procedures are necessary for aspects of fisheries science, invariably inducing a stress response and imposing energetic demands on fish. Anaesthesia or immobilization techniques are often used in an attempt to mitigate stress and improve welfare, yet these also come with their own impacts on post-release recovery. Here we investigated whether changes in cardiac activity (heart rates over time, maxima, and scopes) differed in adult walleye (Sander vitreus) anaesthetised with AQUI-S® 20E (eugenol), electroanaesthetised with a transcutaneous electrical nerve stimulation (TENS) unit, or electrostunned with a commercially developed stunning unit. Read More

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The Effect of Transcoutaneous Electrical Nerve Stimulation on Pain Control during Dental Procedure in Children 9-14 Years Old.

Psychiatr Danub 2021 Spring-Summer;33(Suppl 4):1316-1319

Community Health Center Zagreb-West, Postgraduate studies student, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

Introduction: Transcutaneous electrical nerve stimulation (TENS) is a non-pharmacological method widely used by medical specialists to manage acute and chronic pain in different circumstances. It can be used to manage pain during many dental procedures, as well as pain due to various conditions affecting the maxillofacial region. The aim of this study was to provide insight into the clinical research evidence for the analgetic application of TENS in pediatric patients. Read More

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Nrf2 Activation Mediates Antiallodynic Effect of Electroacupuncture on a Rat Model of Complex Regional Pain Syndrome Type-I through Reducing Local Oxidative Stress and Inflammation.

Oxid Med Cell Longev 2022 14;2022:8035109. Epub 2022 Feb 14.

Department of Neurobiology and Acupuncture Research, The Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Hangzhou 310053, China.

Complex regional pain syndrome type-I (CRPS-I) represents a type of neurovascular condition featured by severe pain in affected extremities. Few treatments have proven effective for CRPS-I. Electroacupuncture (EA) is an effective therapy for pain relief. Read More

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Exercise, Manipulative Therapy, and Physical Modalities in the Treatment of Notalgia Paresthetica: A Case Report.

J Chiropr Med 2021 Dec 6;20(4):224-228. Epub 2022 Apr 6.

Department of Physical Medicine and Rehabilitation, Baskent University Faculty of Medicine, Ankara, Turkey.

Objective: The purpose of this case report is to describe the care of a patient with notalgia paresthetica (NP).

Clinical Features: A 61-year-old man presented with a 7-year history of upper back pain, concentrated in the right periscapular region. Physical examination revealed a hyperpigmented area in the right dorsal paravertebral and infrascapular region with local paraesthesia. Read More

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December 2021

Electroacupuncture relieves postoperative cognitive dysfunction in elderly rats via regulating amp-activated protein kinase autophagy signaling.

Chin J Physiol 2022 Mar-Apr;65(2):87-92

Department of Anesthesiology, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.

Postoperative cognitive dysfunction (POCD) is a common complication after surgery in elderly patients. Electroacupuncture (EA) has been reported to relieve POCD in animal models, but the mechanism remains fully elucidated. The objective of this work was to clarify whether EA could alleviate POCD via regulating autophagy. Read More

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Electroacupuncture attenuates brain injury through α7 nicotinic acetylcholine receptor-mediated suppression of neuroinflammation in a rat model of asphyxial cardiac arrest.

J Neuroimmunol 2022 Jun 20;367:577873. Epub 2022 Apr 20.

Department of Anesthesiology, Tangdu Hospital, Air Force Military Medical University, Xi'an, Shaanxi 710038, China. Electronic address:

We determined whether electroacupuncture (EA) ameliorated brain injury following asphyxial cardiac arrest (CA) and evaluated the role of the α7 nicotinic acetylcholine receptor (α7nAChR)-mediated anti-inflammatory pathway. In CA-induced rats, EA reduced brain injury and promoted behavioral recovery. Morris water maze escape latency time reduced after Baihui (GV20) and Shuigou (DU26) stimulation. Read More

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[Electroacupuncture of "Shangjuxu"(ST37) and "Tianshu"(ST25) reduces colonic injury by suppressing NF-κB/NLRP3 signaling in rats with ulcerative colitis].

Zhen Ci Yan Jiu 2022 Apr;47(4):314-20

School of Acupuncture and Massage, Hunan University of Chinese Medicine, Changsha 410208, China.

Objective: To observe the effect of electroacupuncture (EA) of "Shangjuxu"(ST37) and "Tianshu"(ST25) on colonic mucosal injury and activities of nuclear factor-κB (NF-κB)/Nod-like receptor family,pyrin domain-containing 3 (NLRP3) inflammasome signaling in the colonic tissue in rats with ulcerative colitis (UC), so as to explore its mechanisms underlying improvement of UC.

Methods: Male SD rats were randomly divided into blank, model, medication and EA groups, with 12 rats in each group. The UC model was established by enema of 2-4-6 trinitrobenzene sulfonic acid +50% ethanol (2. Read More

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[Effect of electroacupuncture on pulmonary neuroendocrine cells and secretion of neuroactive substances in lung of COPD rats].

Zhen Ci Yan Jiu 2022 Apr;47(4):305-13

Department of Physiology, College of Integrated Traditional Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei 230038, China; Institute of Acupuncture and Meridian, College of Acupuncture and Massage, Anhui University of Chinese Medicine, Hefei 230038, China.

Objective: To observe the effect of electroacupuncture (EA) at "Zusanli" (ST36) and "Feishu" (BL13) on the activation and secretion of calcitonin gene-related peptide (CGRP) and 5-hydroxytryptamine (5-HT) of pulmonary neuroendocrine cells (PNECs) and inflammatory response in rats with chronic obstructive pulmonary disease (COPD), so as to explore its underlying mechanisms in treating COPD.

Methods: Male SD rats were randomly divided into normal control, COPD model and EA groups, with 7 rats in each group. The COPD model was established by forced inhale of cigarette smoke for 1 h in a self-made box (1 m×1 m×1 m in volume), twice daily for 12 weeks. Read More

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[Effects of electroacupuncture on ROS-NLRP3 inflammatory pathway and autophagy related proteins in hippocampus of vascular dementia rats].

Zhen Ci Yan Jiu 2022 Apr;47(4):298-304

College of Acupuncture-moxibustion and Tuina, Hunan University of Chinese Medicine,Changsha 410208, China.

Objective: To observe the effect of electroacupuncture (EA) on learning-memory ability, ultrastructural changes of hippocampal CA1 neurons, reactive oxygen species (ROS) level, Nod-like receptor protein 3 (NLRP3) and auto-phagy-related proteins expression in the hippocampus of vascular dementia (VD) rats, so as to reveal its partial mechanisms in treating VD.

Methods: Male SD rats were randomly divided into sham operation, model, and EA groups (=10 rats in each group). The VD model was established by permanent ligation of bilateral common carotid arteries. Read More

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Transcutaneous spinal direct current stimulation (tsDCS) does not affect postural sway of young and healthy subjects during quiet upright standing.

PLoS One 2022 28;17(4):e0267718. Epub 2022 Apr 28.

Biomedical Engineering Laboratory, Escola Politécnica, University of São Paulo, São Paulo, Brazil.

Transcutaneous spinal direct current stimulation (tsDCS) is an effective non-invasive spinal cord electrical stimulation technique to induce neuromodulation of local and distal neural circuits of the central nervous system (CNS). Applied to the spinal cord lumbosacral region, tsDCS changes electrophysiological responses of the motor, proprioceptive and nociceptive pathways, alters the performance of some lower limb motor tasks and can even modulate the behavior of supramedullary neuronal networks. In this study an experimental protocol was conducted to verify if tsDCS (5 mA, 20 minutes) of two different polarizations, applied over the lumbosacral region (tenth thoracic vertebrae (T10)), can induce changes in postural sway oscillations of young healthy individuals during quiet standing. Read More

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Influence of transcutaneous electrical nerve stimulation on pain intensity and functional activities following lower segment cesarean section.

Physiother Theory Pract 2022 Apr 28:1-7. Epub 2022 Apr 28.

Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, India.

Background: Postoperative incisional pain following lower segment cesarean section (LSCS) is one of the commonly reported complaints which may affect mother-infant bonding, and restrict mobility and functional activities.

Purpose: To study the influence of transcutaneous electrical nerve stimulation (TENS) on pain intensity and functional activities using the Numerical Pain Rating Scale (NPRS) and the Patient Specific Functional Scale (PSFS) following LSCS from the postoperative day (POD) 1 to POD 4.

Methods: This quasi-experimental study consisted of 50 postpartum women who underwent LSCS and were assigned to an intervention group (IG) that received TENS and a control group (CG) that received routine hospital care. Read More

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Somatosensory Cortex Repetitive Transcranial Magnetic Stimulation and Associative Sensory Stimulation of Peripheral Nerves Could Assist Motor and Sensory Recovery After Stroke.

Front Hum Neurosci 2022 11;16:860965. Epub 2022 Apr 11.

Applied Neuroscience Laboratory, Universidade Federal de Pernambuco, Recife, Brazil.

Background: We investigated whether transcranial magnetic stimulation (rTMS) over the primary somatosensory cortex (S1) and sensory stimulation (SS) could promote upper limb recovery in participants with subacute stroke.

Methods: Participants were randomized into four groups: rTMS/Sham SS, Sham rTMS/SS, rTMS/SS, and control group (Sham rTMS/Sham SS). Participants underwent ten sessions of sham or active rTMS over S1 (10 Hz, 1,500 pulses, 120% of resting motor threshold, 20 min), followed by sham or active SS. Read More

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Effect of electroacupuncture on discomfort during gastroscopy: a study protocol for a randomized controlled trial.

Trials 2022 Apr 27;23(1):364. Epub 2022 Apr 27.

Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Background: Gastroscopy procedures are frequently performed under general sedation to minimize discomfort. Patients who refuse a sedative injection may experience more discomfort and adverse reactions such as pain and nausea. These instances reduce patient compliance and willingness to participate in future procedures. Read More

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Efficacy and safety of electroacupuncture at auricular concha region in promoting of rehabilitation of ischemic stroke patients with upper limb motor dysfunction: A study protocol for a randomized pilot trial.

Medicine (Baltimore) 2022 Apr 15;101(15):e28047. Epub 2022 Apr 15.

Department of Rehabilitation Medicine, The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, China.

Introduction: Ischemic stroke (IS) is the one of the most severe neurological disease, survivors may live with upper limb motor dysfunction (ULMD) resulting in heavy social and economic burden. Nowadays, there are few approaches to promote the rehabilitation of ULMD. Auricular acupuncture (electroacupuncture [EA]) has long been used in the treatment of neurological disorders in China. Read More

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Efficacy of short duration versus conventional electroacupuncture in the treatment of obesity: a randomized crossover study.

J Tradit Chin Med 2022 Apr;42(2):256-263

Department of Pediatrics, Faculty of Medicine, Srinakharinwirot University, Nakorn Nayok 26120, Thailand.

Objective: To compare the efficacy of short duration electroacupuncture (EA) with conventional EA to reduce weight and other parameters in obese Thai women.

Methods: A randomized crossover study was conducted in 76 simple obese women. Participants were randomized to undergo either eight weeks of 30-minute EA (EA30) followed by an eight-week washout period, then eight weeks of five-minute EA (EA5), or EA5 followed by a washout period, then EA30. Read More

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