7,729 results match your criteria Tracheobronchial Tear


Ventilator-associated pneumonia: The central role of transcolonization.

J Crit Care 2018 Dec 6;50:155-161. Epub 2018 Dec 6.

Medical and Surgical Intensive Care Unit, Groupe Hospitalier Paris Saint Joseph, Paris, France; Endotoxins, Structures and Host Response, Department of Microbiology, Institute for Integrative Biology of the Cell, UMR 9891 CNRS-CEA-Paris Saclay University, 98190 Gif-sur-Yvette, France. Electronic address:

Ventilator-associated pneumonia remain frequent and serious diseases since they are associated with considerable crude mortality. Pathophysiology is centered on modifications of regional bacterial flora, especially tracheobronchial tree and oropharyngeal sphere. Bacterial migration from an anatomical area to another seems to be the main explanation of these alterations which are called "transcolonization". Read More

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December 2018

Complete remission after hypofractionated radiotherapy for a patient with inoperable adenoid cystic carcinoma of bronchus: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13463

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Rationale: Tracheobronchial adenoid cystic carcinoma (TACC) is a rare malignancy. Surgical resection remains the standard treatment of choice. But it is frequently unresectable due to its local extension. Read More

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December 2018
1 Read

Experimental evaluation of pressure drop for flows of air and heliox through upper and central conducting airway replicas of 4- to 8-year-old children.

J Biomech 2018 Oct 27. Epub 2018 Oct 27.

Department of Mechanical Engineering, University of Alberta, Canada. Electronic address:

Airway resistance describes the ratio between pressure drop and flow rate through the conducting respiratory airways. Analytical models of airway resistance for tracheobronchial airways have previously been developed and assessed without upper airways positioned upstream of the trachea. This work investigated pressure drop as a function of flow rate and gas properties for upper and central airway replicas of 10 child subjects, ages 4-8. Read More

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October 2018

Management of broncholithiasis.

J Thorac Dis 2018 Oct;10(Suppl 28):S3419-S3427

Division of Cardiothoracic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Broncholithiasis is a condition in which calcified material has entered the tracheobronchial tree, at times causing airway obstruction and inflammation. Broncholiths generally originate as calcified material in mediastinal lymph nodes that subsequently erode into adjacent airways, often as a result of prior granulomatous infection. Disease manifestations range from asymptomatic stones in the airway to life-threatening complications, including massive hemoptysis and post-obstructive pneumonia. Read More

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October 2018
4 Reads

[Obstructive tracheobronchitis due to Aspergillus fumigatus in an immunocompetent patient].

Rev Iberoam Micol 2018 Nov 29. Epub 2018 Nov 29.

Servicio de Microbiología, Hospital Universitario Puerta del Mar, Cádiz, España; Instituto de Investigación Biomédica de Cádiz (INiBICA), Cádiz, España.

Background: Aspergillus tracheobronchitis (ATB) is an uncommon type of invasive pulmonary aspergillosis in which fungal involvement is limited to the tracheobronchial tree. While the more severe forms, such as pseudomembranous and ulcerative ATB, occur almost exclusively in immunocompromised patients, the milder obstructive form may occur in patients without immune deficiency.

Case Report: The case of a 32 year-old man with no previous history of illness, who was evaluated for recurrent right lower lobe pneumonia, is presented. Read More

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November 2018
1 Read

Anterior mediastinal masses - A multidisciplinary pathway for safe diagnostic procedures.

J Pediatr Surg 2018 Nov 6. Epub 2018 Nov 6.

Department of Paediatric Surgery, St Georges Hospital NHS Trust, London, UK. Electronic address:

Objective: The objective of this study was to report our multidisciplinary diagnostic approach for patients with anterior mediastinal masses (AMM).

Methods: A retrospective review of patients with AMM at a tertiary pediatric surgical oncology centre (January 2011-December 2016) was performed. We analyzed data on clinical presentation, mode of tissue diagnosis, anesthetic techniques, and complications. Read More

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November 2018
5 Reads

Analysis of Related Factors for the Retention Time of Tracheobronchial Foreign Bodies in Pediatrics.

J Surg Res 2019 Jan 4;233:262-267. Epub 2018 Sep 4.

Department of Otorhinolaryngology, Children's Hospital of Nanjing Medical University, Nanjing, China. Electronic address:

Background: This study aims to investigate the related factors for the retention time of tracheobronchial foreign bodies in infants and children, to provide help for the assessment of the disease, surgical risk, and prognosis.

Materials And Methods: The clinical data of 1060 patients with tracheobronchial foreign bodies from January 2015 to December 2015 were retrospectively studied, and the correlation of the retention time of foreign bodies with age, gender, preoperative complications, granulation formation, operation time, and hospital stay was analyzed.

Results: The retention time of foreign bodies was not correlated with age (r = 0. Read More

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January 2019
1 Read

Computational Fluid Dynamics Modeling of Respiratory Airflow in Tracheobronchial Airways of Infant, Child, and Adult.

Comput Math Methods Med 2018 31;2018:9603451. Epub 2018 Oct 31.

Department of Mathematics, Indian Institute of Technology Roorkee, Roorkee, India.

During human growth and development from infancy to adulthood, dramatic changes occur in the respiratory system. It is important to understand respiratory airflow in different age groups in age-specific treatment of respiratory disorders. This study numerically investigated the age-related effects on inspiratory and expiratory airflow dynamics in four-generation lung airway models under normal breathing conditions. Read More

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October 2018

The Role and Prognostic Significance of Aortopulmonary, Anterior Mediastinal, and Tracheobronchial Lymph Nodes in Esophageal Cancer: Update of the Eighth-Edition TNM Staging System (2018).

Ann Surg Oncol 2018 Dec 3. Epub 2018 Dec 3.

Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China.

Background: The eighth edition of TNM staging for esophageal cancer will be implemented at 2018. The stations 5, 6, and 10 lymph nodes (LNs) have been omitted from the regional lymph node map for the new TNM staging. However, the role and prognostic significance of these LN stations were not clear. Read More

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December 2018
1 Read

Predictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma.

Cancer Manag Res 2018 19;10:5919-5925. Epub 2018 Nov 19.

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China,

Purpose: To identify potential risk factors of lymph node metastasis and to verify the prognostic significance of the lymph node ratio (LNR) and the total number of lymph nodes examined (NNE) in tracheobronchial adenoid cystic carcinoma (ACC) patients, using a large population-based database.

Patients And Methods: From Surveillance, Epidemiology, and End Results database, we identified 263 patients with tracheobronchial ACC in whom complete lymph node data could be obtained. Logistic regression analysis was performed to determine predictive factors of nodal metastasis. Read More

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November 2018
1 Read

Rosai-Dorfman disease of the trachea: an extremely rare benign tumor.

Asian Cardiovasc Thorac Ann 2018 Dec 3:218492318817677. Epub 2018 Dec 3.

3 Department of Cardiothoracic Surgery, Apollo Hospital, Chennai, India.

Rosai-Dorfman disease or sinus histiocytosis is a nonmalignant disease chiefly presenting as a painless cervical lymphadenopathy, although extranodal involvement is also frequent. Involvement of the tracheobronchial tree is extremely rare, and there are no clear guidelines on management. Rosai-Dorfman disease usually presents as a tracheal tumor, although it may also present with extraluminal compression. Read More

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December 2018
2 Reads

Adverse Human Health Impacts in the Anthropocene.

Authors:
Richard Olawoyin

Environ Health Insights 2018 16;12:1178630218812791. Epub 2018 Nov 16.

Department of Industrial and Systems Engineering, School of Engineering and Computer Science, Oakland University, Rochester, MI, USA.

This commentary presents a summarized discussion of key findings and relevant ideas from previously published study, index analysis, and human health risk model application for evaluating ambient air-heavy metal contamination in Chemical Valley Sarnia (CVS). The CVS study provides previously unavailable data in the CVS area which evaluates the adverse effects on air quality due to nearby anthropogenic activities. The study provided an assessment of environmental pollutants, finding that carcinogenic and non-carcinogenic substances are present in trace quantities. Read More

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November 2018
3 Reads

[Multiple ulcerated tracheobronchial mucosal lesions in the eosinophilic granulomatosis with polyangiitis].

Rev Pneumol Clin 2018 Dec 24;74(6):516-519. Epub 2018 Nov 24.

Service de pneumologie, CHL, Strassen, Luxembourg.

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December 2018
1 Read

Particle deposition in the human lung: Health implications of particulate matter from different sources.

Environ Res 2018 Nov 14;169:237-245. Epub 2018 Nov 14.

Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.

Although ambient particulate matter or particles have been found to be associated with morbidity and mortality all over the world, specific health effects of particles from different sources need further elucidation. The objective of this work is to predict the deposition of particles from different sources in the human lung. The whole lung, consisting of 24 generations of branches from trachea to alveoli, was approximated using a one-dimensional lumped "trumpet" model with a variable cross-sectional area. Read More

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November 2018

Multiple Bifurcated Covered Self-Expanding Metallic Stents for Complex Tracheobronchial Fistulas or Stenosis.

Cardiovasc Intervent Radiol 2018 Nov 21. Epub 2018 Nov 21.

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China.

Objective: We aimed to determine the safety and feasibility of bifurcated covered self-expanding stents for the treatment of complex tracheobronchial fistulas or stenosis.

Methods: Twenty-eight patients were treated by multiple bifurcated covered airway stents (Micro-Tech Co. Ltd. Read More

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November 2018
1 Read

Bronchoscopic management of prolonged air leak.

J Thorac Dis 2018 Oct;10(Suppl 27):S3352-S3355

Department of Thoracic Surgery, Maggiore Teaching Hospital, Bologna, Italy.

Broncho-pleural fistula (BPF) is an atypical communication between the tracheobronchial tree and the alveolar/pleural space, with prolonged air leak (PAL). BPF is frequent and related to significant morbidity, prolonged length of hospital stay, and mortality. Nevertheless, in about 10%, more than 5 days of an air leak is considered a PAL, accounted for significant morbidity. Read More

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October 2018
4 Reads

Traumatic Airway Injuries: Role of Imaging.

Curr Probl Diagn Radiol 2018 Oct 29. Epub 2018 Oct 29.

Department of Radiology and Department of Surgery, JPN Apex trauma Center, All India Institute of Medical Sciences, New Delhi, India.

Airway Injuries are rare but often immediately life threatening. Incidence ranges from 0.5-2 % in blunt and 1-6 % in penetrating trauma. Read More

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October 2018
3 Reads

[Efficacy and safety of cryotherapy combined with balloon dilatation through electronic bronchoscope in the management of airway occlusion caused by scar stenosis type of tracheobronchial tuberculosis].

Zhonghua Jie He He Hu Xi Za Zhi 2018 Nov;41(11):857-862

Department of Endoscopic Diagnosis & Treatment, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China.

To investigate the efficacy and safety of cryotherapy combined with balloon dilatation through electronic bronchoscope in the management of airway occlusion caused by scar stenosis type of tracheobronchial tuberculosis (TBTB). From December 2008 to May 2016, 98 cases of airway occlusion caused by scar stenosis of TBTB were diagnosed by microbiology, histopathology, CT (computer tomography), bronchial reconstructions and bronchoscopy. All patients underwent routine anti-tuberculosis chemotherapy and cryotherapy through bronchoscope. Read More

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November 2018
2 Reads

[Two cases of tracheotomy in children's tracheobronchial foreign body misdiagnosis].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(20):1588-1589

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October 2018
1 Read

Neonatal Stridor: Diagnosis and Management.

Clin Perinatol 2018 Dec 24;45(4):817-831. Epub 2018 Sep 24.

Department of Otolaryngology, University of Colorado School of Medicine, 12631 E. 17th Avenue, B-205, Aurora, CO 80045, USA. Electronic address:

Stridor, a common presenting sign of respiratory distress in a newborn, has many systemic causes. It may arise from the larynx or the tracheobronchial airway. This article presents the most common pathologic conditions in this anatomic region, with highlights on management. Read More

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December 2018
1 Read

Airway Devices in Ventilator-Associated Pneumonia Pathogenesis and Prevention.

Clin Chest Med 2018 Dec;39(4):775-783

CHU Lille, Critical Care Center, bd du Pr Leclercq, Lille F-59000, France; Lille University, Medicine School, 1 Place de Verdun, Lille F-59000, France. Electronic address:

Airway devices play a major role in the pathogenesis of microaspiration of contaminated oropharyngeal and gastric secretions, tracheobronchial colonization, and ventilator-associated pneumonia (VAP) occurrence. Subglottic secretion drainage is an effective measure for VAP prevention, and no routine change of ventilator circuit. Continuous control of cuff pressure, silver-coated tracheal tubes, low-volume low-pressure tracheal tubes, and the mucus shaver are promising devices that should be further evaluated by large randomized controlled trials. Read More

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December 2018
6 Reads

Application of multiple-path particle dosimetry model for quantifying age specified deposition of particulate matter in human airway.

Ecotoxicol Environ Saf 2019 Jan 30;168:241-248. Epub 2018 Oct 30.

Department of Civil Engineering, Indian Institute of Technology Madras (IITM), Chennai 600 036, Tamil Nadu, India. Electronic address:

Particulate matter (PM) is crucial among six criteria air pollutants, and it is frequently associated with human morbidity and mortality. According to the aerodynamic diameter, PM is classified as coarse (PM) and fine (PM). PM with these smaller sizes can easily enter and get deposited in the human airways. Read More

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January 2019
13 Reads

Acquired tracheoesophageal fistula repair, due to prolonged mechanical ventilation, in patient with double incomplete aortic arch.

Monaldi Arch Chest Dis 2018 Oct 30;88(3):974. Epub 2018 Oct 30.

University of Padua, Department of Cardiologic, Thoracic and Vascular Sciences.

We report a case of the repair of an acquired benign tracheoesophageal fistula (TEF) after prolonged mechanical invasive ventilation. Patient had an unknown double incomplete aortic arch determining a vascular ring above trachea and esophagus. External tracheobronchial compression, caused by the vascular ring, increasing the internal tracheoesophageal walls pressure determined by endotracheal and nasogastric tubes favored an early TEF development. Read More

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October 2018
3 Reads

Plastic Bronchitis in an AIDS Patient with Pulmonary Kaposi Sarcoma.

Case Rep Pulmonol 2018 27;2018:9736516. Epub 2018 Sep 27.

Department of Medicine, Division of Infectious Diseases, UTH-SA, San Antonio, TX 78229, USA.

Plastic bronchitis is the expectoration of bronchial casts in the mold of the tracheobronchial tree. It is a rare occurrence of unknown etiology that has been primarily described in children with congenital heart disease. In this case report, we present the first reported case of plastic bronchitis in a patient with pulmonary Kaposi sarcoma and underlying HIV infection. Read More

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September 2018
12 Reads

Radiation Therapy for Tracheobronchial Metastases from Head and Neck Squamous Cell Carcinoma.

Cureus 2018 Aug 15;10(8):e3151. Epub 2018 Aug 15.

Department of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, USA.

Tracheobronchial metastases from head and neck squamous cell carcinoma (HNSCC) represent a rare occurrence, with few reported cases in the literature. Here, we present two patients with HNSCC who developed tracheobronchial metastases at different time points in their disease course. Patient 1 presented with a localized tonsillar primary, underwent tonsillectomy and post-operative radiation therapy to the tumor bed and bilateral neck, and experienced multiple subsequent metastases in different locations throughout the tracheobronchial tree. Read More

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August 2018
7 Reads

Case Report: Severe back pain, epigastric distress and refractory nausea; an unusual presentation of mediastinal bronchogenic cyst.

F1000Res 2018 28;7:960. Epub 2018 Jun 28.

Internal Medicine Residency, Florida Hospital Orlando, Orlando, FL, 32803, USA.

Bronchogenic cysts are congenital malformations from abnormal budding of embryonic foregut and tracheobronchial tree. We present a case of bronchogenic cyst with severe back pain, epigastric distress and refractory nausea and vomiting.   A 44-year-old Hispanic female presented with a 3-week history of recurrent sharp interscapular pain radiating to epigastrium with refractory nausea and vomiting. Read More

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June 2018
8 Reads

Right main bronchial pleomorphic adenoma: A case report and literature review.

Medicine (Baltimore) 2018 Oct;97(42):e12648

Department of Pulmonary and Critical Care Medicine, Second Affiliated Hospital of Fujian Medical University, Respiratory Medicine Center of Fujian Province, Licheng District, Quan Zhou, P.R. China.

Rationale: Tracheobronchial benign tumors are uncommon; particularly, bronchial pleomorphic adenoma is one of the rarest benign tumors that develop in bronchus (only 7 reported cases, among which only 4 cases of pleomorphic adenoma were seen arising from right main bronchus).

Patient Concerns: In this report, a 38-year-old woman suffered from progressive shortness of breath for 5 years due to right main bronchial pleomorphic adenoma.

Diagnoses: The patient was diagnosed as right main bronchial pleomorphic adenoma based on chest computed tomography enhanced scan, bronchoscopy, and histological examination. Read More

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October 2018
5 Reads

Influenza-mediated reduction of lung epithelial ion channel activity leads to dysregulated pulmonary fluid homeostasis.

JCI Insight 2018 Oct 18;3(20). Epub 2018 Oct 18.

Department of Anesthesiology and Perioperative Medicine, Division of Molecular and Translational Biomedicine.

Severe influenza (IAV) infection can develop into bronchopneumonia and edema, leading to acquired respiratory distress syndrome (ARDS) and pathophysiology. Underlying causes for pulmonary edema and aberrant fluid regulation largely remain unknown, particularly regarding the role of viral-mediated mechanisms. Herein, we show that distinct IAV strains reduced the functions of the epithelial sodium channel (ENaC) and the cystic fibrosis transmembrane regulator (CFTR) in murine respiratory and alveolar epithelia in vivo, as assessed by measurements of nasal potential differences and single-cell electrophysiology. Read More

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October 2018
2 Reads

Predictors of Outcomes in Patients with Prolonged Weaning with Focus on Respiratory Tract Pathogens and Infection.

Respiration 2018 Oct 17:1-10. Epub 2018 Oct 17.

Kliniken für Pneumologie und Infektiologie, Thoraxzentrum Ruhrgebiet, Herne, Germany.

Background: The impact of respiratory tract pathogens and infection on outcomes in patients with prolonged weaning is largely unknown.

Objective: We studied predictors of weaning outcomes (death and failure to achieve spontaneous ventilation) in a population treated during a 3.5-year period in a specialized and certified weaning centre. Read More

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October 2018
6 Reads

Pulmonary artery sling anomaly presenting with unilateral lung hyperinflation: A case r.

Turk J Pediatr 2018 ;60(2):194-197

Department of Radiology, Tepecik Training and Research Hospital, Izmir, Turkey.

Şahin H, Pekçevik Y. Pulmonary artery sling anomaly presenting with unilateral lung hyperinflation: A case report. Turk J Pediatr 2018; 60: 194-197. Read More

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January 2018
2 Reads

Prenatal diagnosis of congenital high airway obstruction syndrome.

Indian J Radiol Imaging 2018 Jul-Sep;28(3):366-368

Department of Obstetrics and Gynecology, University Hospital of Getafe, Getafe, Madrid, Spain.

Congenital high airway obstruction syndrome (CHAOS) is a rare sequence due to a complete obstruction of the fetal airway that blocks the larynx or trachea, either intrinsic atresia or extrinsic compression (e.g., congenital neck mass). Read More

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October 2018
1 Read

Penetrating shrapnel injury to the chest presenting as a delayed tracheoesophageal fistula (TEF). A case report.

Trauma Case Rep 2018 Oct 26;17:5-8. Epub 2018 Sep 26.

American University of Beirut Medical Center, Department of Surgery, Lebanon.

Tracheo-esophageal fistulae (TEF) due to trauma are rare. We report a case of a delayed TEF caused by a shrapnel from a blast. A 25-year-old male was admitted to the hospital after sustaining a blast injury. Read More

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October 2018
1 Read

Airborne particles in the city center of Kuala Lumpur: Origin, potential driving factors, and deposition flux in human respiratory airways.

Sci Total Environ 2019 Feb 7;650(Pt 1):1195-1206. Epub 2018 Sep 7.

Global Center for Clean Air Research (GCARE), Department of Civil and Environmental Engineering, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford GU2 7XH, Surrey, United Kingdom.

Equatorial warming conditions in urban areas can influence the particle number concentrations (PNCs), but studies assessing such factors are limited. The aim of this study was to evaluate the level of size-resolved PNCs, their potential deposition rate in the human respiratory system, and probable local and transboundary inputs of PNCs in Kuala Lumpur. Particle size distributions of a 0. Read More

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February 2019

C-reactive protein and procalcitonin profile in ventilator-associated lower respiratory infections.

J Crit Care 2018 Dec 2;48:385-389. Epub 2018 Oct 2.

Unidade de Cuidados Intensivos Polivalente, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, Lisboa, Portugal; NOVA Medical School, CEDOC, Universidade Nova de Lisboa, Lisboa, Portugal.

Purpose: Ventilator-associated tracheobronchitis (VAT) has been suggested as an intermediate process between tracheobronchial colonization and ventilator-associated pneumonia (VAP) in patients receiving mechanical ventilation. The aim of this study was to evaluate the ability of C-reactive protein (CRP) and procalcitonin (PCT) to differentiate between VAT and VAP.

Methods: Pre-planned analysis of the prospective multinational TAVeM database, performed on 2960 patients receiving mechanical ventilation for >48 h, including 689 patients with VA-LRTI. Read More

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December 2018
2 Reads

Pulmonary endoscopy emergencies.

Panminerva Med 2018 Oct 5. Epub 2018 Oct 5.

University of Parma, Parma, Italy.

In clinical practice, interventional pulmonologist faces several situations which can lead to dramatic consequences especially on ventilation and require immediate intervention. We describe the main pathological conditions where urgent bronchoscopy is crucial because they act through mechanisms such as airway obstruction or alteration of the anatomic integrity of the tracheobronchial tree. We point out the problems resulting from inhalation of foreign bodies, one of the most dramatic respiratory emergencies typical of childhood which needs not only the appropriate endoscopic equipment suitable for the age, but also great experience in the management of the possible related complications. Read More

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October 2018
6 Reads

Three-dimensional printed degradable splint in the treatment of pulmonary artery sling associated with severe bilateral bronchus stenosis.

Cardiol Young 2018 Dec 10;28(12):1477-1480. Epub 2018 Oct 10.

1Department of Cardiovascular Surgery,Xijing Hospital,Fourth Military Medical University,Xi'an,China.

Pulmonary artery sling is a congenital cardiovascular disease and is usually accompanied by tracheobronchial stenosis. Generally, infants diagnosed with pulmonary artery sling should have surgery. However, the treatment of tracheobronchial stenosis is still controversial. Read More

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December 2018
1 Read

Reply to Galante, Dario, regarding their comment 'Tracheobronchial angles in children: Can it change during anesthesia?'

Paediatr Anaesth 2018 Oct;28(10):930

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio.

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October 2018
1 Read
1.740 Impact Factor

Metallic hair pin aspiration into the left tertiary bronchus.

Malays Fam Physician 2018 31;13(2):36-38. Epub 2018 Aug 31.

School of Medical Sciences, Universiti Sains Malaysia Health Campus, 16150 Kota Bharu Kelantan, Malaysia.

Foreign body aspiration is commonly described in infants and children. However, recently, a new high-risk group was identified among young women, especially those from the Muslim population who wear the traditional hair scarf. This is due to the habit of holding the scarf pin in between the lips to free hands to adjust the scarf more easily. Read More

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August 2018
2 Reads

Expiratory Central Airway Collapse in Adults: Anesthetic Implications (Part 1).

J Cardiothorac Vasc Anesth 2018 Aug 31. Epub 2018 Aug 31.

Augusta University, Medical College of Georgia, Augusta, GA.

Expiratory central airway collapse (ECAC) is a general term that incorporates tracheobronchomalacia (TBM) and excessive dynamic airway collapse (EDAC). TBM and EDAC are progressive, degenerative disorders of the tracheobronchial tree, causing airway collapse. Induction of general anesthesia can trigger intraoperative airway collapse in patients with these conditions. Read More

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August 2018
1 Read

Submicron particle number doses in the human respiratory tract: implications for urban traffic and background environments.

Environ Sci Pollut Res Int 2018 Nov 1;25(33):33724-33735. Epub 2018 Oct 1.

Department of Chemistry, Environmental Pollution Control Laboratory, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

The deposition of ambient submicron particles in the different parts of the human respiratory tract (HRT) was, for the first time, estimated for males and females from different age classes (children-adults-seniors) of urban population in the city of Thessaloniki, northern Greece, during the cold and the warm period of the year. Outdoor daily and hourly particle number doses in the different regions of the HRT, i.e. Read More

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November 2018

Foreign Body-Related Extremity Trauma in Children: A Single-Center Experience.

Authors:
Anil Agarwal

Indian J Orthop 2018 Sep-Oct;52(5):481-488

Department of Paediatric Orthopaedics, Chacha Nehru Bal Chikitsalaya, New Delhi, India.

The extremity foreign body in a child has propensity of getting missed or mistaken diagnosis. We report our experience of extremity foreign body trauma in order to increase awareness of this disease entity. The retrospective series of 24 retained foreign bodies was based on a 10-year chart review of emergency data (ICD code Z18). Read More

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September 2018

Intercellular Communication between Airway Epithelial Cells is Mediated by Exosome-Like Vesicles.

Am J Respir Cell Mol Biol 2018 Sep 19. Epub 2018 Sep 19.

University of North Carolina, Marsico Lung Institute, Chapel Hill, North Carolina, United States ;

Airway epithelium structure/function can be altered by local inflammatory/immune signals, and this process is called epithelial remodeling. The mechanism by which this innate response is regulated, which causes mucin/mucus overproduction, is largely unknown. Exosomes are nano-vesicles that can be secreted and internalized by cells to transport cellular cargo, such as proteins, lipids, and miRNA. Read More

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September 2018

Characteristics of indoor air pollution and estimation of respiratory dosage under varied fuel-type and kitchen-type in the rural areas of Telangana state in India.

Sci Total Environ 2019 Feb 29;650(Pt 1):616-625. Epub 2018 Aug 29.

Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036, India. Electronic address:

Indoor Air Pollution (IAP) is one of the top environmental risks in developing countries including India, with more than a million deaths annually, predominantly through Particulate Matter (PM) exposure. The current study deals with the measurement of PM concentrations in rural households under varied fuel and kitchen-types, evaluation of the indoor air pollution (IAP) characteristics and estimation of respiratory dosage for the different subjects (women, young children and the elderly). Monitoring of particulate matter (PM) was carried out during summer, monsoon and winter season with biomass, LPG and combine of biomass and LPG being used as fuel for cooking. Read More

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February 2019
5 Reads

The utility of 3D-printed airway stents to improve treatment strategies for central airway obstructions.

Drug Dev Ind Pharm 2018 Sep 25:1-10. Epub 2018 Sep 25.

a Centre for Lung Cancer Research , Woolcock Institute of Medical Research , Sydney , NSW , Australia.

Airway stents are commonly used in the management of patients suffering from central airway obstruction (CAO). CAO may occur directly from airway strictures, obstructing airway cancers, airway fistulas or tracheobronchomalacia, resulting from the weakening and dynamic collapse of the airway wall. Current airway stents are constructed from biocompatible medical-grade silicone or from a nickel-titanium (nitinol) alloy with fixed geometry. Read More

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September 2018
1 Read

Incidence and Predictors of Tracheobronchial Tuberculosis in Pulmonary Tuberculosis: A Multicentre, Large-Scale and Prospective Study in Southern China.

Respiration 2018 Sep 11:1-7. Epub 2018 Sep 11.

State Key Laboratory of Respiratory Disease, Guangzhou Institute for Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

Background: Patients with pulmonary tuberculosis (PTB) have a high risk of concomitant tracheobronchial tuberculosis (TBTB), which commonly causes severe complications such as tracheobronchial stenosis. The prevalence and predictors of TBTB in China remain unclear due to the lack of prospective and large-scale studies.

Objectives: To investigate the incidence of TBTB in PTB patients in southern China, and elucidate the predictors of TBTB and related tracheobronchial stenosis. Read More

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September 2018

Unearthing a consistent bilateral R1 component of the laryngeal adductor reflex in awake humans.

Laryngoscope 2018 Nov 8;128(11):2581-2587. Epub 2018 Sep 8.

Department of Otolaryngology Head and Neck Surgery, Mount Sinai West Hospital, New York, New York, U.S.A.

Objective: The laryngeal adductor reflex (LAR) is an essential tracheobronchial protective mechanism resulting in vocal fold adduction to laryngeal stimulation. It was thought to consist of an early ipsilateral R1 component and a later, bilateral but highly centrally modulated R2 component. We recently demonstrated that bilateral R1 responses are robustly present in humans under general anesthesia. Read More

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November 2018
4 Reads

A case of anti-melanoma differentiation-associated gene 5 antibody-positive interstitial lung disease complicated with tracheobronchial ulcers.

Respir Med Case Rep 2018 24;25:189-191. Epub 2018 Aug 24.

Department of Respiratory Medicine, Saitama Red Cross Hospital, Saitama, Japan.

We herein report the first case, to our knowledge, of tracheobronchial ulcer with anti-melanoma differentiation-associated gene 5 (anti-MDA 5) antibody-positive interstitial lung disease (ILD). A 53-year-old man complained of shoulder and wrist pain and was suspected of having polymyalgia rheumatica at another hospital. Thereafter, treatment with prednisolone was started. Read More

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August 2018
2 Reads

Migrating foreign body in an adult bronchus: An aspirated denture.

J Dent Anesth Pain Med 2018 Aug 28;18(4):267-270. Epub 2018 Aug 28.

Department of Anaesthesiology, Tata Main Hospital, Jamshedpur, India.

As a safety measure, dentures are routinely removed before surgery. Aspiration of a denture could be catastrophic, with medicolegal implications. Foreign body aspiration is uncommon in adults; however, aspirations may remain asymptomatic and undiagnosed for long periods of time. Read More

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August 2018
1 Read

Posterior Thoracic Stab Wounds: Evaluating the Value of Commonly Used Radiologic Modalities.

Am Surg 2018 Aug;84(8):1363-1367

This study was performed to assess our institution's experience with stab injuries to the posterior mediastinal box. We examine the value of performing CT of the chest and esophagram in conjunction with a chest X-ray (CXR) over performing CXR(s) alone in evaluating this group of patients. We performed a retrospective study covering a 10-year period consisting of patients with stab wounds to the posterior mediastinal box. Read More

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