9,823 results match your criteria Tracheal Tumors


Clinical Characteristics and Prognosis of Primary Tracheal Cancer: A Single Institution Experience.

Int J Hematol Oncol Stem Cell Res 2018 Oct;12(4):298-302

Department of Radiation Oncology, Cancer Care Manitoba, University of Manitoba, Winnipeg, Manitoba, Canada.

Primary tracheal cancers (PTCs) are rare and current evidence-based understanding is limited to retrospective reports and national databases. We present single institutional study of a historical cohort of PTC from Canadian provincial cancer registry database. After institutional research ethics board approval, all PTC patients diagnosed from 1980 to 2014 were identified through the Canadian provincial cancer registry. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375374PMC
October 2018
1 Read

Competing risk analysis of primary tracheal carcinoma based on SEER database.

Cancer Manag Res 2019 24;11:1059-1065. Epub 2019 Jan 24.

Department of Oncology, Chang'An Hospital, Xi'an, Shaanxi, China,

Purpose: To analyze the prognostic factors of primary tracheal carcinoma.

Patients And Methods: All patients of primary tracheal carcinoma were extracted from the Surveillance, Epidemiology, and End Results database during 1973-2015. The potential prognostic factors were analyzed by using the competing risk analysis of R statistical software. Read More

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http://dx.doi.org/10.2147/CMAR.S190124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353024PMC
January 2019

[Laryngo-Tracheal Resection as an Alternative to Permanent Tracheostomy].

Pneumologie 2019 Jan 31. Epub 2019 Jan 31.

Lungenklinik Köln-Merheim, Lehrstuhl für Thoraxchirurgie, Kliniken der Stadt Köln gGmbH, private Universität Witten/Herdecke, Köln.

Introduction:  Cervical stenosis of the trachea caused by tracheotomy, tumor or without defined reason (idiopathic) can be treated by resection and anastomosis with good early and long-term results. Involvement of the ring cartilage makes the procedure technically demanding and increases the risk of morbidity. We describe our technique of laryngotracheal resection and reconstruction and compare the perioperative results with standard tracheal resection. Read More

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http://dx.doi.org/10.1055/a-0809-0232DOI Listing
January 2019
1 Read

Diagnostic pitfalls in a cystic ectopic intrathyroidal parathyroid adenoma mimicking a nodular goiter: A care-compliant case report.

Medicine (Baltimore) 2019 Feb;98(5):e14351

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Rationale: Cystic parathyroid adenomas are rare and seldom arise in ectopically located glands which may be found within the carotid sheath, mediastinum, thymus, or thyroid grand. They cannot be detected consistently by any imaging methods. Unusual symptoms may bring about certain pitfalls and difficulties for the diagnosis of primary hyperparathyroidism (PHPT) caused by cystic parathyroid adenomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000014351DOI Listing
February 2019
2 Reads

[Surgery of primary tracheal tumours of the salivary gland type].

Rev Mal Respir 2019 Jan 25. Epub 2019 Jan 25.

Service de chirurgie thoracique, CHU Hassan II, BP. 1893, Km 2.200, route de Sidi Harazem, 30000 Fès, Maroc; Faculté de médecine et de pharmacie, université Sidi Mohamed Ben Abdellah, Fès, Maroc.

Introduction: Primary tumours of the trachea are very rare and may develop from the tracheal salivary glands.

Case Reports: We describe four patients operated on in our service between 2010 and 2017 of whom two had an adenocystic carcinoma, one a mucoepidermoid carcinoma and one a pleomorphic adenoma of the trachea. All were treated by resection and tracheal anastomosis with clear margins in three cases. Read More

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http://dx.doi.org/10.1016/j.rmr.2019.01.001DOI Listing
January 2019
1 Read

The role of combined techniques of scintigraphy and SPECT/CT in the diagnosis of primary hyperparathyroidism: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14154

"Lucian Blaga" University of Sibiu, Romania.

Rationale: Primary hyperparathyroidism, usually as a result of a hyperfunctioning parathyroid gland, represents more than 90% cases of patients evaluated for hypercalcemia. Combined techniques of preoperative scintigraphy and SPECT/CT serve as a successful minimally-invasive parathyroidectomy. This recent imaging method provides four-dimensional functional images with advanced contrast resolution which greatly facilitates preoperative localization of parathyroid adenomas. Read More

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http://dx.doi.org/10.1097/MD.0000000000014154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358356PMC
January 2019
1 Read

[Application of Enhanced Recovery after Surgery in Interventional Treatment 
of Tracheal Malignant Tumor].

Zhongguo Fei Ai Za Zhi 2019 Jan;22(1):1-5

Department of Respiratory, Meitan General Hospital, Beijing 100028, China.

Currently, enhanced recovery after surgery (ERAS) has been widely accepted by surgery and anesthesiology all over the world, and applied in colorectal surgery, gynecology, liver surgery, breast surgery, urology and spinal surgery. But ERAS are rarely used in the field of interventional bronchoscopy. In recent years, more and more researchers have begun to explore the application of ERAS in bronchoscopic interventional therapy. Read More

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http://dx.doi.org/10.3779/j.issn.1009-3419.2019.01.02DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348157PMC
January 2019

VivaSight™ single-lumen tube guided bronchial blocker placement for one-lung ventilation in a patient with a tracheal tumor under video-assisted transthoracic surgery: a case report.

BMC Anesthesiol 2019 Jan 5;19(1). Epub 2019 Jan 5.

Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Background: Video-assisted transthoracic surgery (VATS) is a minimally invasive procedure that has been reported as a valid method for tracheal resection and reconstruction. However, for patients with tracheal tumors, one-lung ventilation during VATS is difficult to achieve, and utilizing a double-lumen tube is not applicable in these types of situations. When using a bronchial blocker, a fiberoptic bronchoscope is required to verify the position of bronchial blocker, though the repeated use of the fiberoptic bronchoscope increases the risk of tumor rupture and hemorrhage. Read More

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http://dx.doi.org/10.1186/s12871-018-0677-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320586PMC
January 2019
1 Read

Surgical treatment result of giant thyroid tumor: Case series in Vietnam.

Int J Surg Case Rep 2019 24;54:103-107. Epub 2018 Nov 24.

Department of Oncology, Hanoi Medical University, No 1 Ton That Tung Street, Dong Da District, Hanoi, Viet Nam; Department of Oncology and Palliative Care, Hanoi Medical University Hospital, No 1 Ton That Tung Street, Dong Da District, Hanoi, Viet Nam. Electronic address:

Introduction: Giant thyroid tumors can be associated with severely compressive symptoms and surgery is inevitable for treatment strategy. However, the risk of surgical complications is higher as well as the duration of operation may be longer than those of small thyroid tumors.

Presentation Of Cases: Two patients with large neck tumors were admitted with history of thyroid goiters for more than 10 years. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312799PMC
November 2018
1 Read

Nomograms for predicting survival outcomes in patients with primary tracheal tumors: a large population-based analysis.

Cancer Manag Res 2018 11;10:6843-6856. Epub 2018 Dec 11.

Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, People's Republic of China,

Background: The aim of this study was to develop and validate reliable nomograms to predict individual overall survival (OS) and cancer-specific survival (CSS) for patients with primary tracheal tumors and further estimate the role of postoperative radiotherapy (PORT) for these entities.

Patients And Methods: A total of 405 eligible patients diagnosed between 1988 and 2015 were selected from the Surveillance, Epidemiology, and End Results database. All of them were randomly divided into training (n=303) and validation (n=102) sets. Read More

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http://dx.doi.org/10.2147/CMAR.S186546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294060PMC
December 2018
2 Reads

Transthoracic radiofrequency ablation for hepatic tumor located beneath the diaphragm under one-lung ventilation: A case report.

Medicine (Baltimore) 2018 Dec;97(51):e13863

Department of Anesthesiology and Pain Medicine, College of Medicine, Kyung Hee University, Seoul, Korea.

Rationale: Radiofrequency ablation (RFA) has become the reliable, effective, and less invasive treatment for small primary or metastatic hepatic tumors. Hepatic tumors that located immediately beneath the diaphragm are difficult to treat with percutaneous RFA due to poor visualization by percutaneous ultrasonography and the close location of the heart or lung. A transthoracic approach has been proposed to be an alternative for hepatic tumors located beneath the diaphragm that are difficult to access by conventional percutaneous or laparoscopic approaches. Read More

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http://dx.doi.org/10.1097/MD.0000000000013863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320126PMC
December 2018
2 Reads

A preclinical micro-computed tomography database including 3D whole body organ segmentations.

Sci Data 2018 12 18;5:180294. Epub 2018 Dec 18.

Institute for Experimental Molecular Imaging, University Hospital Aachen, Forckenbeckstr. 55, 52074 Aachen, Germany.

The gold-standard of preclinical micro-computed tomography (μCT) data processing is still manual delineation of complete organs or regions by specialists. However, this method is time-consuming, error-prone, has limited reproducibility, and therefore is not suitable for large-scale data analysis. Unfortunately, robust and accurate automated whole body segmentation algorithms are still missing. Read More

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http://dx.doi.org/10.1038/sdata.2018.294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298256PMC
December 2018

Nivolumab therapy for lung cancer with tracheo-parenchymal fistula: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13739

Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Minami-ku.

Rationale: Tracheobronchial fistulas are rare complications in lung cancer patients. These lesions are associated with a high rate of mortality caused by infection and bleeding, and there is no consensus on a definitive optimal therapy.

Patient Concerns And Diagnoses: The patient was a 59-year-old man with a right lung mass showing mediastinal invasion and tracheal compression, diagnosed with adenocarcinoma, cT4N0M0, stage IIIA. Read More

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http://dx.doi.org/10.1097/MD.0000000000013739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320206PMC
December 2018

Preliminary study on application of augmented reality visualization in robotic thyroid surgery.

Ann Surg Treat Res 2018 Dec 26;95(6):297-302. Epub 2018 Nov 26.

Department of Biomedical Engineering, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Purpose: Increased robotic surgery is attended by increased reports of complications, largely due to limited operative view and lack of tactile sense. These kinds of obstacles, which seldom occur in open surgery, are challenging for beginner surgeons. To enhance robotic surgery safety, we created an augmented reality (AR) model of the organs around the thyroid glands, and tested the AR model applicability in robotic thyroidectomy. Read More

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http://dx.doi.org/10.4174/astr.2018.95.6.297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255749PMC
December 2018
4 Reads

Predictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma.

Cancer Manag Res 2018 19;10:5919-5925. Epub 2018 Nov 19.

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China,

Purpose: To identify potential risk factors of lymph node metastasis and to verify the prognostic significance of the lymph node ratio (LNR) and the total number of lymph nodes examined (NNE) in tracheobronchial adenoid cystic carcinoma (ACC) patients, using a large population-based database.

Patients And Methods: From Surveillance, Epidemiology, and End Results database, we identified 263 patients with tracheobronchial ACC in whom complete lymph node data could be obtained. Logistic regression analysis was performed to determine predictive factors of nodal metastasis. Read More

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http://dx.doi.org/10.2147/CMAR.S182069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250114PMC
November 2018
2 Reads

Profiles of genomic alterations in primary esophageal follicular dendritic cell sarcoma: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13413

The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Medical School of Nanjing University & Clinical Cancer Institute of Nanjing University, Nanjing.

Rationale: Follicular dendritic cell (FDC) sarcoma is a rare tumor with FDC differentiation that typically arises within lymph nodes but can also occur extranodally. To date, the primary esophageal FDC sarcoma has not been reported in the English literature.

Patient Concerns: We described a 67-year-old female who foremostly presented with dysphagia, and the patient was readmitted due to a dry cough and pain of his right shoulder 2 years after initial treatment. Read More

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http://dx.doi.org/10.1097/MD.0000000000013413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283200PMC
November 2018
3 Reads

Successful Intubation Using the Airtraq Double Lumen with the Universal Adapter for Smartphones in a Case of Intubation Difficulty.

Tokai J Exp Clin Med 2018 Dec 20;43(4):143-147. Epub 2018 Dec 20.

Department of Anesthesiology, Hachioji-hospital, Tokai University School of Medicine, 1838 Ishikawamachi, Hachioji, Tokyo 192-0032, Japan:

Objective: The Universal Adapter for Smartphones c an record s till images and movies during intubation using the monitor display and recording functions of a smartphone. Here, we describe the successful use of the Airtraq Double Lumen with the Universal Adapter for Smartphones for airway management during anesthesia in a patient with intubation difficulty.

Methods: A 78-year-old man required thoracoscopic upper lobectomy for a pulmonary tumor. Read More

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December 2018
7 Reads

[The clinicopathological features and curative effect of the bronchoscopic interventional therapy combined with radiotherapy for the treatment of locally recurrent lung adenoid cystic carcinoma].

Zhonghua Zhong Liu Za Zhi 2018 Nov;40(11):864-868

Department of Oncology, Shanghai Pudong New Area People's Hospital, Pudong New Area, Shanghai 201299, China.

To explore the clinical value of endoscopic interventional therapy for locally recurrent primary lung adenoid cystic carcinoma (ACC). The clinical data of 42 patients with locally recurrent ACC were retrospectively analyzed, and the differences of tracheal and bronchial diameter, airway scoring grade and airway obstruction degree before and after treatment were compared among three treatment methods: bronchoscopic interventional therapy + palliative radiotherapy, interventional therapy alone, and non-interventional therapy. Log rank test and Cox proportional risk model multi-factor analysis were used to determine the prognostic factors of ACC patients with local recurrence, and the long-term effect of bronchoscopic interventional therapy on ACC with local recurrence was determined. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2018.11.013DOI Listing
November 2018
8 Reads

Multiple Bifurcated Covered Self-Expanding Metallic Stents for Complex Tracheobronchial Fistulas or Stenosis.

Cardiovasc Intervent Radiol 2019 Mar 21;42(3):426-432. Epub 2018 Nov 21.

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China.

Objective: We aimed to determine the safety and feasibility of bifurcated covered self-expanding stents for the treatment of complex tracheobronchial fistulas or stenosis.

Methods: Twenty-eight patients were treated by multiple bifurcated covered airway stents (Micro-Tech Co. Ltd. Read More

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http://dx.doi.org/10.1007/s00270-018-2126-6DOI Listing
March 2019
9 Reads

Central Airway Obstruction Due to Tracheal Glomus Tumor.

Thorac Cardiovasc Surg Rep 2018 Jan 20;7(1):e43-e45. Epub 2018 Nov 20.

Department of Surgery, Division of Cardiothoracic Surgery, University of California, San Francisco; San Francisco, California, United States.

 Tracheal glomus tumors are rare mesenchymal neoplasms that have the potential to cause malignant, central airway obstruction. They require a thoughtful approach to safely secure the airway and definitively resect the tumor.  We report the clinical course of a 25-year-old man in severe respiratory distress secondary to tracheal glomus tumor and the subsequent surgical management. Read More

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http://dx.doi.org/10.1055/s-0038-1675411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246109PMC
January 2018

The clinical feasibility of flexible bronchoscopy interventional therapy in patients with central airway stenosis and respiratory failure caused by malignancy.

Onco Targets Ther 2018 1;11:7709-7714. Epub 2018 Nov 1.

Department of Respiratory Medicine, Jiangning Hospital Affiliated to Nanjing Medical University, Nanjing 211100, Jiangsu, China,

Objective: The aim of this study was to investigate the clinical effects and feasibility of using flexible bronchoscopy intervention in cases of malignancy that causes central airway stenosis and respiratory failure.

Methods: The clinical data of patients who were admitted to the Department of Respiratory Medicine at the First Affiliated Hospital of Nanjing Medical University and underwent treatment of a malignant tumor with central airway stenosis and respiratory failure by flexible bronchos-copy from February 2010 to May 2013 were analyzed using a retrospective method. The age, gender, location, extent of airway stenosis, interventional therapy, efficacy, and complications for 12 patients were collected and analyzed using the SPSS 13. Read More

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http://dx.doi.org/10.2147/OTT.S175825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219122PMC
November 2018
8 Reads
1.342 Impact Factor

Primary tracheal hyalinizing clear cell carcinoma.

Lung Cancer 2018 Nov 14;125:100-102. Epub 2018 Sep 14.

Department of Medicine, Section of Pulmonary, Critical Care, and Sleep Medicine, Virginia Tech Carilion School of Medicine, 1906 Belleview Ave Roanoke VA, 24014, United States.

Hyalinizing clear cell carcinomas (HCCC), now referred to as clear cell carcinomas (CCC) by the World Health Organization (WHO), are rare tumors usually arising from the salivary glands of the head and neck. We present the first case of a CCC originating from the trachea. A 66 year-old woman with history of hypertension, former smoker, presented to the emergency department reporting worsening shortness of breath. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01695002183056
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http://dx.doi.org/10.1016/j.lungcan.2018.09.009DOI Listing
November 2018
8 Reads

Laser Treatment of a Tracheal Inflammatory Myofibroblastic Tumor.

Indian Pediatr 2018 Oct;55(10):907-908

Department of Anesthesiology; Kanchi Kamakoti CHILDS Trust Hospital, Chennai, India.

Background: Inflammatory myofibroblastic tumors of the trachea are rare childhood quasi-neoplastic lesions.

Case Characteristics: 7-year-old boy with recurrent episodes of cough, breathing difficulty and wheeze, initially treated as asthma.

Intervention: CT chest and flexible bronchoscopy revealed a mass lesion of the trachea, which was excised by diode laser through the ventilating bronchoscope. Read More

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October 2018
1 Read

Programmed death ligand 1 and CD8+ immune cell infiltrates in resected primary tracheal malignant neoplasms.

Eur J Cardiothorac Surg 2018 Nov 12. Epub 2018 Nov 12.

Division of Thoracic Surgery, Massachusetts General Hospital, Boston, MA, USA.

Objectives: Many patients with primary malignant tracheal neoplasms are not surgical candidates nor do they experience residual or recurrent disease after surgery and may benefit from alternative therapies. This study explores the expression of programmed death ligand 1 (PD-L1) in patients with primary tracheal malignancy as a biomarker for candidacy for treatment with immune checkpoint inhibitors.

Methods: We conducted a retrospective review of the medical records of 23 patients with resected primary tracheal malignant tumours from 2010 to 2016. Read More

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https://academic.oup.com/ejcts/advance-article/doi/10.1093/e
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http://dx.doi.org/10.1093/ejcts/ezy370DOI Listing
November 2018
5 Reads

Relapsing polychondritis: state of the art on clinical practice guidelines.

RMD Open 2018 18;4(Suppl 1):e000788. Epub 2018 Oct 18.

Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Centre National de Référence des Maladies Systémiques et Auto-immunes Rares (RESO), INSERM-UMRS 1109, F-67000, Strasbourg, France.

Due to the rarity of relapsing polychondritis (RP), many unmet needs remain in the management of RP. Here, we present a systematic review of clinical practice guidelines (CPGs) published for RP, as well as a list of the most striking unmet needs for this rare disease. We carried out a systematic search in PubMed and Embase based on controlled terms (medical subject headings and Emtree) and keywords of the disease and publication type (CPGs). Read More

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http://rmdopen.bmj.com/lookup/doi/10.1136/rmdopen-2018-00078
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http://dx.doi.org/10.1136/rmdopen-2018-000788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203097PMC
October 2018
15 Reads

Perioperative management of an anterior mediastinal teratoma in an infant: one more tool in the toolbox.

BMJ Case Rep 2018 Nov 1;2018. Epub 2018 Nov 1.

Surgery, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee, USA.

Anterior mediastinal masses present a significant challenge in the perioperative period. Standard anaesthetic induction and airway management are often not feasible due to the risk of complete respiratory and/or cardiovascular collapse. Invasive manoeuvres, such as extracorporeal membrane oxygenation, cardiac bypass, or tracheal or bronchial stenting, are sometimes not applicable due to significant anatomic aberration. Read More

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http://dx.doi.org/10.1136/bcr-2018-227022DOI Listing
November 2018
8 Reads

ECMO-assisted resection of huge thoracic mass.

J Cardiovasc Thorac Res 2018 21;10(3):174-176. Epub 2018 May 21.

Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Some advanced thoracic malignancy cannot be resected safely by using of conventional ventilation, so some sort of cardiopulmonary support is needed for hemodynamic and ventilation management of the patient. Using extracorporeal membrane oxygenation (ECMO) in comparing with cardiopulmonary bypass has some advantages. Three patients with huge thoracic tumors with different ages experienced major surgery in our center by using ECMO in order to face major complications mainly due to the size of mass to achieve better hemostatic stabilities, lower bleeding, and injuries to main airways and secure oxygenation. Read More

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http://dx.doi.org/10.15171/jcvtr.2018.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203866PMC
May 2018
8 Reads

Surveillance for Cancers Associated with Tobacco Use - United States, 2010-2014.

MMWR Surveill Summ 2018 11 2;67(12):1-42. Epub 2018 Nov 2.

Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, CDC.

Problem/condition: Tobacco use is the leading preventable cause of cancer, contributing to at least 12 types of cancer, including acute myeloid leukemia (AML) and cancers of the oral cavity and pharynx; esophagus; stomach; colon and rectum; liver; pancreas; larynx; lung, bronchus, and trachea; kidney and renal pelvis; urinary bladder; and cervix. This report provides a comprehensive assessment of recent tobacco-associated cancer incidence for each cancer type by sex, age, race/ethnicity, metropolitan county classification, tumor characteristics, U.S. Read More

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http://www.cdc.gov/mmwr/volumes/67/ss/ss6712a1.htm?s_cid=ss6
Publisher Site
http://dx.doi.org/10.15585/mmwr.ss6712a1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220819PMC
November 2018
2 Reads

Are Papillary Thyroid Carcinomas That Are Candidates for Active Surveillance in Fact Classical Microcarcinomas Restricted to the Gland?

Eur Thyroid J 2018 Oct 13;7(5):258-261. Epub 2018 Jul 13.

Santa Casa de Belo Horizonte, Belo Horizonte, Brazil.

Background: Patients with small papillary thyroid carcinomas (PTC) can currently be maintained under active surveillance (AS). The recommended criteria are the following: adult individual, tumor ≤1 cm and not adjacent to the trachea or recurrent laryngeal nerve, cytology non-suggestive of the aggressive subtype, absence of lymph node (LN) involvement and extrathyroidal extension (ETE) on ultrasonography (US), and absence of clinical distant metastases. This study aimed to evaluate the frequency of the following peri- and postoperative findings in patients who met the criteria for PTC being candidate for AS: tumor > 1 cm, aggressive subtype or vascular invasion, ETE, clinical LN metastases (cN1), and distant metastases. Read More

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http://dx.doi.org/10.1159/000490701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198768PMC
October 2018

Emergency Tracheal Surgery for Adenoid Cystic Carcinoma: A Rare Entity.

J Coll Physicians Surg Pak 2018 Nov;28(11):882-884

Department of Thoracic Surgery, Combined Military Hospital, Lahore, Pakistan.

Primary tumours of the trachea are rare. Adenoid cystic carcinoma (ACC) constitutes less than 1% of these tumours. They occasionally masquerade as asthma. Read More

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https://www.jcpsp.pk/archive/2018/Nov2018/17.pdf
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http://dx.doi.org/10.29271/jcpsp.2018.11.882DOI Listing
November 2018
8 Reads

Resection and Reconstruction of the Trachea for the Treatment of Upper Tracheal Stenosis: Tracheal Versus Non-Tracheal Intubation.

J Coll Physicians Surg Pak 2018 Nov;28(11):879-881

Department of Anesthesiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China.

Tracheal stenosis may occur secondary to trauma, tumors, infections, and inflammatory and iatrogenic diseases. Patients with tracheal stenosis must be evaluated carefully and require comprehensive preoperative examination, including pulmonary function tests and radiographic studies. Two male patients (one 18 years of age and the other 46 years of age) with tracheal stenosis were scheduled for tracheal resection and reconstruction. Read More

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https://www.jcpsp.pk/archive/2018/Nov2018/16.pdf
Publisher Site
http://dx.doi.org/10.29271/jcpsp.2018.11.879DOI Listing
November 2018
11 Reads
0.320 Impact Factor

Thoracic Organ Doses and Cancer Risk from Low Pitch Helical 4-Dimensional Computed Tomography Scans.

Biomed Res Int 2018 24;2018:8927290. Epub 2018 Sep 24.

Department of Biomedical Engineering, Tianjin University, Tianjin, China.

Purpose: To investigate the dose depositions to organs at risk (OARs) and associated cancer risk in cancer patients scanned with 4-dimensional computed tomography (4DCT) as compared with conventional 3DCT.

Methods And Materials: The radiotherapy treatment planning CT image and structure sets of 102 patients were converted to CT phantoms. The effective diameters of those patients were computed. Read More

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https://www.hindawi.com/journals/bmri/2018/8927290/
Publisher Site
http://dx.doi.org/10.1155/2018/8927290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174794PMC
January 2019
8 Reads

Application of lateral tarsoconjunctival flap to correct ocular complications of Madelung's disease: A case report and literature review.

Medicine (Baltimore) 2018 Oct;97(42):e12864

Department of Ophthalmology, Tri-Service General Hospital.

Rationale: Madelung's disease is a specific type of benign symmetric lipomatosis, which is characterized by overgrowing fat distributed at the neck and shoulder. This excessive fat accumulation may occur in different regions, including vital organs, such as the larynx, trachea, or the orbits. Surgery is usually performed to correct the esthetic or functional concern of the affected area. Read More

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http://dx.doi.org/10.1097/MD.0000000000012864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211917PMC
October 2018
13 Reads

Large endotracheal tumour presenting as severe COPD: flow-volume loop analysis, not always a straightforward diagnostic test.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Internal Medicine - Division of Pulmonary and Critical Care Medicine, University of Iowa - Carver College of Medicine, Iowa City, IA, USA.

The flow-volume loop (FVL) analysis is typically helpful in establishing the diagnosis of airway obstruction caused by endobronchial lesions. In this report, we describe a patient with emphysema and tobacco abuse who presented with chronic dry cough and severe chronic obstructive pulmonary disease (COPD) refractory to standard therapy. The initial FVL showed a relatively normal forced expiratory peak flow shape followed by a smooth flattening of the expiratory curve on spirometry, a pattern consistent with distal airway obstruction as seen in severe asthma or COPD. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22643
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http://dx.doi.org/10.1136/bcr-2018-226430DOI Listing
October 2018
2 Reads

Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumors in Bronchus.

Am J Med Sci 2019 Jan 22;357(1):75-80. Epub 2018 Aug 22.

Department of Medical imaging, The Second Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address:

Ewing sarcoma/peripheral primitive neuroectodermal tumors (ES/pPNET), a member of the Ewing sarcoma family of tumors, is a malignant soft tissue tumor with small undifferentiated neuroectodermal cells. Primary trachea-bronchial ES/pPNET is very rare. The most common pulmonary ES is due to a metastasis. Read More

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http://dx.doi.org/10.1016/j.amjms.2018.08.009DOI Listing
January 2019
8 Reads

IDH mutation status in a series of 88 head and neck chondrosarcomas: different profile between tumors of the Skull Base and tumors involving the facial skeleton and the Layngotracheal tract.

Hum Pathol 2018 Oct 5. Epub 2018 Oct 5.

CHRU de Tours, Service d'Anatomie et Cytologie Pathologiques, Tours, France; Université François Rabelais, Faculté de Médecine, Tours, France; Laboratoire d'étude des sarcomes osseux et remodelage des tissus calcifiés, PhyOS - INSERM UMR 1238, Faculté de Médecine de Nantes, Université de Nantes, 44034 Nantes, cedex 1, France. Electronic address:

Chondrosarcomas are rare primary malignant bone tumors that involve the head and neck region in 1% to 12% of cases. Central conventional chondrosarcoma is the most common subtype and is associated with isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) gene mutations in 50% to 60% of cases. We aimed to define the frequency of IDH1 and IDH2 gene mutations in a multicenter series of 88 cases of chondrosarcoma of the head and neck, including tumors involving the base of the skull (n=30), the facial skeleton (n=11), and the laryngeal and tracheal cartilages (n=47). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00468177183037
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http://dx.doi.org/10.1016/j.humpath.2018.09.015DOI Listing
October 2018
6 Reads

[Application of gastric pull up and complex laryngotracheal flap to reconstruct the circumferencial defect after resection of the hypopharyngeal and cervical esophageal cancers].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;53(9):661-667

Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Shenyang 110042, China.

To evaluate the efficacy of gastric pull-up and complex laryngotracheal flap in reconstruction for circumferencial defects after resection of hypopharyngeal and cervical esophageal cancers. A total of 163 cases (152 males, 11 females) with circumferencial defect after resection of hypopharyngeal and cervical esophageal cancers received reconstructive surgeries by gastric pull-up (42 cases) and complex laryngo-tracheal flaps (121 cases), of them 115 cases simultaneously underwent unilateral neck dissection and 20 cases had bilateral neck dissection. Postoperative radiotherapy was used in 67 cases, with a dosage of 40-60 Gy. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1673-0860.2018.09.005DOI Listing
September 2018
20 Reads

Mediastinal ectopic thyroid mass with normal thyroid function and location: Case report.

Int J Surg Case Rep 2018 29;52:5-7. Epub 2018 Sep 29.

King Fahad Military Medical Complex, Dharan, Saudi Arabia. Electronic address:

Introduction: Mediastinal Ectopic Thyroid Gland is a rare entity, accounting for 1% of all mediastinal tumours. Here, we present a rare case of mediastinal mass that was proved to be an ectopic thyroid with normal thyroid function tests and normal thyroid gland in the cervical location.

Case Presentation: A 32-year-old lady had a road traffic accident, with the incidental discovery of a mediastinal mass on chest radiography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612183040
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http://dx.doi.org/10.1016/j.ijscr.2018.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172445PMC
September 2018
14 Reads

Adenoid cystic carcinoma: A study of 19 cases of salivary and extra-salivary tumours diagnosed by fine needle aspiration cytology.

Diagn Cytopathol 2018 Dec 3;46(12):1004-1009. Epub 2018 Oct 3.

Department of Pulmonary Medicine, Government Medical College and Hospital, Chandigarh, India.

Background: Adenoid cystic carcinoma (ACC) arises at sites where seromucinous or sweat gland epithelium is present and commonly affects the salivary glands. Rarely it can occur at extra-salivary locations.

Methods: A retrospective analysis of 19 cases of ACC diagnosed on fine needle aspiration cytology (FNAC) over a period of 15 y (2002-2016) was made. Read More

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http://doi.wiley.com/10.1002/dc.24075
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http://dx.doi.org/10.1002/dc.24075DOI Listing
December 2018
13 Reads

Prodigiosin-Emerged PI3K/Beclin-1-Independent Pathway Elicits Autophagic Cell Death in Doxorubicin-Sensitive and -Resistant Lung Cancer.

J Clin Med 2018 Oct 3;7(10). Epub 2018 Oct 3.

Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 97401, Taiwan.

Prodigiosin (PG) belongs to a family of prodiginines isolated from gram-negative bacteria. It is a water insoluble red pigment and a potent proapoptotic compound. This study elucidates the anti-tumor activity and underlying mechanism of PG in doxorubicin-sensitive (Dox-S) and doxorubicin-resistant (Dox-R) lung cancer cells. Read More

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http://www.mdpi.com/2077-0383/7/10/321
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http://dx.doi.org/10.3390/jcm7100321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210934PMC
October 2018
13 Reads

[Pattern of lymph node metastasis and choice of lymphadenectomy in patients with thoracic esophageal squamous cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Sep;21(9):987-994

Department of Thoracic Surgery, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China

Esophageal squamous cancer is a malignancy with high incidence and mortality. Surgery currently remains the most important part of the comprehensive treatments. The number of metastatic lymph node has great influence on the prognosis of esophageal cancer, so thorough lymphadenectomy also becomes a key factor. Read More

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September 2018
8 Reads

Case report: presentation of delayed tracheal perforation after hemithyroidectomy.

AME Case Rep 2018 17;2:24. Epub 2018 May 17.

Division of Head and Neck Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Hemithyroidectomy is a low-risk, outpatient procedure commonly performed for benign and some small, differentiated thyroid malignancies. Delayed tracheal perforation following thyroid surgery is exceedingly rare and has previously only been reported after total thyroidectomy. We describe a 25-year-old patient who underwent an unremarkable right hemithyroidectomy to remove a 4-centimeter fine needle aspiration cytologically indeterminate thyroid nodule, and presented 4 weeks later with acute anterior neck swelling and subcutaneous emphysema after strenuous exercise. Read More

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http://dx.doi.org/10.21037/acr.2018.05.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155615PMC
May 2018
6 Reads

Intraluminal tracheal lipoma as a rare cause of dyspnoea in a dog.

Acta Vet Scand 2018 Sep 27;60(1):59. Epub 2018 Sep 27.

Department of Equine and Small Animal Medicine, PL 57, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, 00014, Helsinki, Finland.

Background: Tracheal tumors are rarely diagnosed in veterinary medicine and the majority of tracheal neoplasia reported in adult dogs are malignant. Intratracheal lipoma has not been previously reported in the veterinary literature.

Case Presentation: A 7-year-old Briard dog was evaluated for inspiratory dyspnoea and an inspiratory wheeze. Read More

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https://actavetscand.biomedcentral.com/articles/10.1186/s130
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http://dx.doi.org/10.1186/s13028-018-0413-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161456PMC
September 2018
15 Reads

Successful management of a patient with radiological presentation of choriocarcinoma syndrome before induction chemotherapy.

J Cancer Res Ther 2018 Sep;14(Supplement):S803-S805

Department of Urology and Andrology, Graduate School of Medicine, Kansai Medical University, Osaka, Japan.

Choriocarcinoma syndrome is a life-threatening lysis syndrome caused by blood vessel rupture and subsequent tumor bleeding. We describe a case of pretreatment choriocarcinoma syndrome that developed in a 27-year-old man. He underwent a high orchiectomy at a local hospital and was diagnosed with metastatic testicular tumor given the high serum human chorionic gonadotropin levels (943,601 mIU/mL). Read More

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http://www.cancerjournal.net/text.asp?2018/14/10/803/175433
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http://dx.doi.org/10.4103/0973-1482.175433DOI Listing
September 2018
16 Reads

Non-circumferential membranous resection of the trachea for paraganglioma: A case report.

Int J Surg Case Rep 2018 17;51:288-291. Epub 2018 Sep 17.

Service of Thoracic Surgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. Electronic address:

Introduction: Paraganglioma is a rare neuroendocrine tumor and may sometimes be located in the membranous part of the trachea.

Presentation Of Case: We report the case of a 52-year-old man presenting a paraganglioma just above the carina with obstructive symptoms. The patient successfully underwent a non-circumferential tracheal membranous resection, followed by latissimus dorsi muscle flap repair, under peripheral extra-corporeal membrane oxygenation (ECMO). Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.09.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148838PMC
September 2018
2 Reads

[A Case of Mediastinal Small Cell Lung Cancer in a Patient Receiving Mechanical Ventilation Who Was Successfully Treated with Chemotherapy and Finally Extubated].

Gan To Kagaku Ryoho 2018 Sep;45(9):1335-1337

Dept. of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine.

Background: The efficacy and safety of chemotherapy for patients with lung cancer who are in need of intensive care, such as invasive mechanical ventilation, have not been established.

Case: A 59-year-old woman consulted a doctor with complaints of dyspnea.She was intubated because of acute respiratory failure and transferred to our hospital. Read More

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September 2018
1 Read

Primary intratracheal schwannoma resected during bronchoscopy using argon plasma coagulation.

BMJ Case Rep 2018 Sep 18;2018. Epub 2018 Sep 18.

Department of Interventional Pulmonology, JFK Medical Center, Atlantis, Florida, USA.

A 63-year-old man presented with intermittent, progressively worsening dyspnoea associated with cough and blood-tinged sputum. Initial work-up showed left axis deviation on ECG, chest X-ray with an elevated left hemidiaphragm and a non-contrast CT chest that showed a multilobulated mass in the proximal trachea. Bronchoscopy showed a whitish-appearing lesion, which was then sampled and partially resected with pathology showing a schwannoma with no malignant cells. Read More

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http://dx.doi.org/10.1136/bcr-2018-225140DOI Listing
September 2018
1 Read

Ultrasonographic features associated with false-negative and false-positive results of extrathyroidal extensions in papillary thyroid microcarcinoma.

Eur Arch Otorhinolaryngol 2018 Nov 3;275(11):2817-2822. Epub 2018 Sep 3.

Department of Otolaryngology-Head and Neck Surgery, Kyung Hee University School of Medicine, #1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702, South Korea.

Purpose: To assess the ultrasonographic features affect accuracy of extrathyroid extension (ETE) evaluation on preoperative ultrasonography (US) in papillary thyroid microcarcinoma (PTMC).

Methods: Of the total patients who underwent thyroid surgery, 516 patients with a tumor measuring less than 1 cm on preoperative US were enrolled in this study. One blinded head and neck radiologist reviewed the preoperative US images to evaluate the US features of PTMC, and the pathologic reports were reviewed. Read More

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http://dx.doi.org/10.1007/s00405-018-5115-0DOI Listing
November 2018
12 Reads

Life-threatening giant esophageal neurofibroma with severe tracheal stenosis: a case report.

Surg Case Rep 2018 Sep 3;4(1):107. Epub 2018 Sep 3.

Department of Surgery, Saiseikai Yokohamashi Tobu Hospital, 3-6-1 Shimosueyoshi, Tsurumi-ku, Yokohama, Kanagawa, 230-0012, Japan.

Background: Benign esophageal tumors are relatively rare, and a neurofibroma in the esophagus is extremely rare. Dysphagia is the most common clinical manifestation in patients with esophageal neurofibroma, and no cases of giant esophageal neurofibroma with severe tracheal stenosis have been reported.

Case Presentation: A 73-year-old woman presented with shortness of breath, and computed tomography scan exhibited a giant mediastinal tumor causing severe tracheal stenosis. Read More

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http://dx.doi.org/10.1186/s40792-018-0517-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120858PMC
September 2018
13 Reads

Acellular and Cellular Lung Model to Study Tumor Metastasis.

J Vis Exp 2018 08 19(138). Epub 2018 Aug 19.

Department of Surgery, Houston Methodist Hospital Research Institute; Division of Thoracic Surgery, Department of Surgery, Weill Cornell Medical College, Houston Methodist Hospital;

It is difficult to isolate tumor cells at different points of tumor progression. We created an ex vivo lung model that can show the interaction of tumor cells with a natural matrix and continual flow of nutrients, as well as a model that shows the interaction of tumor cells with normal cellular components and a natural matrix. The acellular ex vivo lung model is created by isolating a rat heart-lung block and removing all the cells using the decellularization process. Read More

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http://dx.doi.org/10.3791/58145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128209PMC
August 2018
10 Reads