Search Our Scientific Publications & Authors

Am J Emerg Med 2018 Dec 11. Epub 2018 Dec 11.

Department of Anesthesiology, Saitama Medical University Hospital, Moroyama, Saitama, 350-0495, Japan.

Clin Lab 2018 Oct;64(11)

Background: Tracheobronchopathia osteochondroplastica (TO) is a rare benign disease. We report a case of TO. Methods: Chest CT scan and bronchoscope with biopsy was performed for diagnosis and blood tests explored for the latent etiology. Read More

J Small Anim Pract 2018 Dec 13. Epub 2018 Dec 13.

Lodi's ICU and Sub ICU Head, ASST Lodi 26900, Italy.

Objective: To describe the technique and findings of the 'veterinary focused assessment with sonography for trauma-airway, breathing, circulation, disability and exposure' protocol in dogs suffering from trauma.

Materials And Methods: Prospective observational study on a new point-of-care ultrasound protocol on 64 dogs suffering from trauma and comparison of findings with radiology.

Results: Comparison of the results of this new ultrasound protocol for trauma patients with radiography findings for pneumothorax, pleural effusion, alveolar-interstitial syndrome and abdominal effusion revealed positive agreement of 89, 83, 100 and 87% and negative agreement of 76, 83, 76 and 92%, respectively. Read More

J Leukoc Biol 2018 Dec 13. Epub 2018 Dec 13.

Surgery, Washington University School of Medicine in Saint Louis, St. Louis, Missouri, USA.

Tracheitis secondary to placement of an endotracheal tube (ETT) is characterized by neutrophil accumulation in the tracheal lumen, which is generally associated with epithelial damage. Mitochondrial DNA (mtDNA), has been implicated in systemic inflammation and organ dysfunction following trauma; however, less is known about the effects of a foreign body on local trauma and tissue damage. We hypothesized that tracheal damage secondary to the ETT will result in local release of mtDNA at sufficient levels to induce TLR9 and NF-κB activation. Read More

Prenat Diagn 2018 Dec 12. Epub 2018 Dec 12.

Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.

Objective: To develop Z-scores for the trachea and main bronchi in normal fetuses.

Methods: This was a prospective cross-sectional study in 823 normal singleton fetuses. The tracheal diameter immediately proximal to the bifurcation as well as the left and right main bronchial diameters were measured from their inner to inner edge in the coronal view. Read More

Methods Mol Biol 2019 ;1894:313-322

Department of Environmental and Occupational Health Sciences, School of Public Health and Information Sciences, University of Louisville, Louisville, KY, USA.

Nanoparticles can enter the body via the lungs, the digestive tract, and the skin. The pulmonary effects of nanoparticles and the underlying mechanisms may be investigated by histopathological examination, immunostaining, bronchoalveolar lavage (BAL), and so on. BAL is a simple, fast, and inexpensive method that is commonly used to investigate the immune cells and acellular components in the lungs, which reflect the health state of the lungs. Read More

Exp Ther Med 2018 Dec 15;16(6):5021-5024. Epub 2018 Oct 15.

Pneumology Department, The Affiliated Traditional Medical Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830000, P.R. China.

The aim of this study was to investigated the functional changes of airway epithelial cells and mitochondria in rat models of asthenic lung and phlegm blocking combined with cough variant asthma (CVA). Sixteen Sprague-Dawley rats were randomly divided into two groups: Control and model group, with 8 rats in each group. On the basis of the CVA rat model induced and sensitized by ovalbumin and aluminum hydroxide, the rat models with asthenic lung and phlegm blocking combined with CVA were established via smoking stimulation. Read More

Medicine (Baltimore) 2018 Dec;97(49):e13170

Department of Anesthesiology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine.

The ETView tracheoscopic ventilation tube (TVT) is a tracheal tube (TT) incorporating a video camera and a light source in its tip. The view from the tip appears continuously on a portable monitor in the anesthesia area. We evaluated the effectiveness and usefulness of the single/double ETView TVT in monitoring the tracheal tube position during general anesthesia undergoing video-assisted thoracoscopic lobectomy. Read More

Clin Biomech (Bristol, Avon) 2018 Dec 7;61:105-111. Epub 2018 Dec 7.

School of Engineering, RMIT University, PO Box 71, Bundoora, VIC 3083, Australia; Key Laboratory of Ministry of Education for Advanced Reactor Engineering and Safety, Institute of Nuclear and New Energy Technology, Tsinghua University, PO Box 1021, Beijing 100086, China. Electronic address:

Background: Understanding respiratory physiology can aid clinicians in diagnosing the cause of respiratory symptoms or shed light on drug delivery inhaler device optimisation. However, the sheer complexity of the human lung prohibits a full-scale study.

Methods: In this study, a realistic respiratory airway model including large-to-small conducting airways was built. Read More

Transpl Immunol 2018 Dec 10. Epub 2018 Dec 10.

Department of Pathology, Keio University School of Medicine, Tokyo, Japan.

Bronchiolitis obliterans (BO), which begins with lymphocytic bronchiolitis (LB), is the most serious manifestations of chronic rejection following lung transplantation. We have evaluated the effects of intraperitoneal administration of pioglitazone, a peroxisome proliferator-activated receptor (PPAR) gamma agonist, on LB in mice tracheal transplant model. Tracheal grafts from BALB/c or C57BL/6 were transplanted to C57BL/6 recipients. Read More

A A Pract 2018 Dec 7. Epub 2018 Dec 7.

Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin.

A patient presented with a stab injury caused by a knife penetrating the orbital floor and maxillary sinus along the skull base with the tip situated adjacent to the left internal carotid artery. A flexible fiberoptic bronchoscope loaded with an endotracheal tube was initially positioned superior to the vocal cords and advanced into the trachea immediately following induction. The blade was removed after occluding endovascular balloons were positioned distal and proximal to the potential internal carotid artery injury site. Read More

Clin Oral Investig 2018 Dec 12. Epub 2018 Dec 12.

Department of Dental Anesthesiology, Faculty of Dental Science, Kyushu University, Fukuoka, Japan.

Objectives: The selection of an appropriate size of tracheal tube is important for airway management. For nasotracheal intubation, passing the nasal cavity should be taken into account for the selection of tube size. The aim of this study was to investigate the selection of appropriate size of nasotracheal tube in pediatric patients retrospectively. Read More

Exp Ther Med 2018 Dec 9;16(6):5003-5008. Epub 2018 Oct 9.

Department of Cardiac Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, P.R. China.

Characteristics of pulmonary infection after mitral valve repair in patients with metabolic syndrome (MS) and its relationships with blood pressure, blood glucose and blood lipid were investigated. Clinical data of 126 patients were retrospectively analyzed, and patients were divided into infection group (n=19) and non-infection group (n=107). The differences of MS components in patients between the two groups were compared, and the distribution of pathogens and related factors of pulmonary infection were analyzed. Read More

Zhonghua Yi Xue Za Zhi 2018 Dec;98(46):3767-3772

Department of Anesthesiology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.

To evaluate the feasibility and safety of supraglottic tracheal tube ventilation by comparing with modified laryngeal mask airway ventilation during painless fiberbronchoscopy. This was a prospective study. Twenty-eight patients undergoing painless fiberbronchoscopy in Hangzhou First People's Hospital were randomly divided into 2 groups(=14): supraglottic tracheal tube ventilation(group A) and modified laryngeal mask airway(group B). Read More

Front Neurol 2018 20;9:985. Epub 2018 Nov 20.

Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.

Invasive procedures were previously developed for measuring pharyngeal collapsibility in rodents during expiration, when declining neuromuscular activity makes the airway unstable. We developed a non-invasive approach for streamlining collapsibility measurements by characterizing responses in physiologic markers of dynamic expiratory airflow obstruction to negative nasal pressure challenges. Anesthetized mice were instrumented to monitor upper airway pressure-flow relationships with head-out plethysmography while nasal pressure was ramped down from ~ +5 to -20 cm HO over several breaths. Read More

J Biomech 2018 Oct 27. Epub 2018 Oct 27.

Department of Mechanical Engineering, University of Alberta, Canada. Electronic address:

Airway resistance describes the ratio between pressure drop and flow rate through the conducting respiratory airways. Analytical models of airway resistance for tracheobronchial airways have previously been developed and assessed without upper airways positioned upstream of the trachea. This work investigated pressure drop as a function of flow rate and gas properties for upper and central airway replicas of 10 child subjects, ages 4-8. Read More

J Formos Med Assoc 2018 Dec 3. Epub 2018 Dec 3.

Department of Anesthesiology, National Taiwan University, College of Medicine and Hospital, No. 7, Chung-Shan S. Rd., Taipei, Taiwan. Electronic address:

Background: Nonintubation anaesthesia for laryngomicrosurgery (LMS) provides both excellent visualization of the surgical field and complete examination on vocal cord. However, adequate oxygenation remains challenging during nonintubated LMS. Recently, transnasal humidified rapid-insufflation ventilator exchange (THRIVE) has been reported effectively maintaining apneic oxygenation in patient with difficult airways. Read More

Mikrobiyol Bul 2018 Oct;52(4):439-443

Kocaeli State Hospital, Clinic of Chest Diseases, Kocaeli, Turkey.

Myiasis; is defined as the infestation of dead or living tissues of humans and animals by the diptera larvae. It is prevalent all over the world, especially in tropical and subtropical countries with low socioeconomic status. Myiasis of humans has been associated with low socioeconomic status, alcoholism, mental or neurological diseases, poor personal hygiene, patients with varicose veins, diabetes, malnutrition, advanced stage cancer, pediculosis, immunosuppression, sexually transmitted disease, gingivitis and other oral cavity lesions. Read More

PLoS One 2018 12;13(12):e0208252. Epub 2018 Dec 12.

Department of Pediatrics, University of Rennes 1,Rennes, France.

Introduction: Most infants born before 30 weeks gestational age (GA) develop respiratory distress syndrome soon after birth. Methods of surfactant administration that avoid ventilation have been recently introduced. The aim of this study was to evaluate the impact of implementing a new procedure of less invasive surfactant administration (LISA) and determine whether it is associated with an improvement in respiratory outcome. Read More

Eur J Anaesthesiol 2018 Dec 11. Epub 2018 Dec 11.

From the Department of Anesthesiology and Intensive Care, C.H.U. Dijon (ER, PI, P-GG, BB, OD-R), Dijon and Université Bourgogne Franche-Comté, LNC UMR866, Dijon Cedex, France (P-GG, BB, OD-R), Anaesthesia and Intensive Care, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, Pavia, Italy (SM, FM) and Unit of Anaesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Pavia, Italy (ER, FM).

Background: Left double-lumen tubes (LDLTs) are used in thoracic surgery to allow one-lung ventilation. Their size is usually chosen on the basis of clinical parameters (height, sex). Double-lumen endobronchial tubes are frequently undersized/oversized, risking tube displacement or tracheal trauma. Read More

Acta Biomed 2018 Dec 7;89(7-S):25-31. Epub 2018 Dec 7.

ASST Monza, Ospedale San Gerardo - università degli Studi di Milano-Bicocca.

Background And Aim: Unplanned extubation (UE) in Intensive Care Units (ICU) is an indicator of quality and safety of care. UEs are classified in: accidental extubations, if involuntarily caused during nursing care or medical procedures; self-extubation, if determined by the patient him/herself.  In scientific literature, the cumulative incidence of UEs varies from 0. Read More

Front Microbiol 2018 27;9:2851. Epub 2018 Nov 27.

School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW, Australia.

Sulfate is an important modulator for virulence factor expression in , the causative organism for whooping cough. During infection, sulfate is released when respiratory epithelial cells are damaged which can affect gene expression. The current predominant strains in Australia are found in single nucleotide polymorphism (SNP) cluster I (). Read More

Pediatr Res 2018 Dec 11. Epub 2018 Dec 11.

Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL, USA.

Background: Inflammation is a key factor in the pathogenesis of bronchopulmonary dysplasia (BPD). Tumor necrosis factor-stimulated protein 6 (TSG-6) is a glycoprotein that modulates inflammation. Here we tested the hypothesis that intra-tracheal (IT) administration of an adenovirus overexpressing TSG-6 (AdTSG-6) would decrease inflammation and restore lung structure in experimental BPD. Read More

Pediatrics 2018 Dec 11. Epub 2018 Dec 11.

Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Background And Objectives: Neonatal tracheal intubation is a critical but potentially dangerous procedure. We sought to characterize intubation practice and outcomes in the NICU and delivery room (DR) settings and to identify potentially modifiable factors to improve neonatal intubation safety.

Methods: We developed the National Emergency Airway Registry for Neonates and collected standardized data for patients, providers, practices, and outcomes of neonatal intubation. Read More

Nurs Crit Care 2018 Dec 9. Epub 2018 Dec 9.

Children's Hospital of Nanjing Medical University, Nanjing, China.

Aim: To compare and evaluate the efficacy and safety of continuous and intermittent control of P .

Methods: We performed a comprehensive and systematic meta-analysis of randomized controlled trials (RCTs) assessing the continuous and intermittent control of P by searching PUBMED, EMBASE and other such databases (from inception to 31 March 2018). Summary odds ratios or mean differences with 95% confidence intervals were calculated using a fixed- or random-effects model. Read More

Cochrane Database Syst Rev 2018 Dec 10;12:CD010593. Epub 2018 Dec 10.

Intensive Care Unit, Second Affiliated Hospital Medical College, Zhejiang University, 88 Jiefang Road, Hangzhou, China, 310009.

Background: Sepsis and septic shock are potentially life-threatening complications of infection that are associated with high morbidity and mortality in adults and children. Fluid therapy is regarded as a crucial intervention during initial treatment of sepsis. Whether conservative or liberal fluid therapy can improve clinical outcomes in patients with sepsis and septic shock remains unclear. Read More

J Ultrasound Med 2018 Dec 11. Epub 2018 Dec 11.

Pediatric Cardiology, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan.

On the basis of 2-dimensional fetal echocardiographic findings, we investigated 4 different fetal vascular ring cases using spatiotemporal image correlation (STIC) combined with high-definition (HD) flow imaging. An in-depth 3-dimensional perspective of aortic arch branching (ie, the brachiocephalic arteries) was created by application of glass body and HDlive flow rendering algorithms (GE Healthcare, Zipf, Austria). Additionally, complete (U- or O-shaped) or incomplete (C-shaped) vascular rings were clearly differentiated in utero, and articulations around the trachea and esophagus were more easily imaged. Read More

Rev Bras Ginecol Obstet 2018 Dec 7;40(12):803-807. Epub 2018 Dec 7.

Department of Anaesthesiology, Centro Hospitalar Lisboa Norte, Lisboa, Portugal.

Thrombocytopenia is the most common hemostatic change in pregnancy, but severe thrombocytopenia is rare. One of the causes, immune thrombocytopenic purpura (ITP), is characterized by increased platelet destruction by immunoglobulin G (IgG) antibodies, presenting a high risk of hemorrhage for the patient, but also for the fetus, since antibodies may cross the placenta. We present the case of a 23-year-old pregnant woman with a history of Langerhans cell histiocytosis of the mandible submitted to surgery and chemotherapy when she was 10 years old, with diagnosis of ITP since then. Read More

Eur Arch Otorhinolaryngol 2018 Dec 10. Epub 2018 Dec 10.

Otorhinolaryngology-Head and Neck Surgery Department, University Hospital of Modena, Largo del Pozzo, 71, 41125, Modena, Italy.

Purpose: Locoregional recurrence of thyroid carcinoma is relatively common and reported rate are between 5 and 20%. Cervical nodes are usually involved, especially at the central compartment. The management of recurrent thyroid carcinoma at central compartment still remains challenging because of higher incidence of complication rate. Read More

Microbiol Resour Announc 2018 Dec 6;7(22). Epub 2018 Dec 6.

Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

The complete genomic sequences of H5N1 highly pathogenic avian influenza (HPAI) viruses were directly obtained from lung, trachea, and colon tissues and an intestinal fecal sample of a patient by using the next-generation sequencing technique. This is the first report on complete H5N1 viral genomes from human autopsy specimens. Read More

Anesth Pain Med 2018 Oct 24;8(5):e80158. Epub 2018 Sep 24.

Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background: The use of short-acting anesthetics, muscle relaxation, and anesthesia depth monitoring allows maintaining sufficient anesthesia depth, fast recovery, and extubation of the patients in the operating room (OR). We evaluated the feasibility of extubation in the OR in cardiac surgery.

Methods: This clinical trial was performed on 100 adult patients who underwent elective noncomplex cardiac surgery using cardiopulmonary bypass. Read More

Case Rep Surg 2018 5;2018:6107982. Epub 2018 Nov 5.

Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan.

Most substernal goiters can be managed through the transcervical approach, but a sternotomy is required in some cases. This report is about a large substernal goiter, which was resected via a transcervical and full sternotomy approach. The patient was a 57-year-old female, who visited our hospital for surgical treatment for a large substernal goiter. Read More

Infect Drug Resist 2018 15;11:2311-2319. Epub 2018 Nov 15.

Department of Clinical Laboratory, Peking University People's Hospital, Beijing, China,

Objective: This study aimed to determine the risk factors for intra-abdominal infections (IAIs), assess the clinical outcomes of IAIs, and investigate the spectrum and antimicrobial resistance of major pathogens causing IAIs.

Patients And Methods: This prospective observational study enrolled patients from the Chinese Antimicrobial Resistance Surveillance of Nosocomial Infections (CARES) program between 2007 and 2016. Data on the clinicopathological factors and causative pathogens were collected. Read More

Indian J Anaesth 2018 Nov;62(11):916-918

Department of Anaesthesiology, Pain Medicine and Critical Care, All India Institute of Medical Sciences, New Delhi, India.

Khirurgiia (Mosk) 2018 (11):11-19

Sechenov First Moscow State Medical University, Moscow, Russia.

Aim: To analyze long-term outcomes of tracheal transplantation.

Material And Methods: There were 1128 patients with cicatricial tracheal stenosis who have been operated at the Petrovsky Russian Research Center for Surgery and the Sechenov First Moscow State Medical University for the period 1963-2015.

Results: Operations have become safer. Read More

Shock 2018 May 4. Epub 2018 May 4.

Div. of Surgical Research/Department of Surgery, Lifespan-Rhode Island Hospital and Brown University, Providence, RI, USA.

Therapeutic interventions to treat acute lung injury (ALI) remain largely limited to lung-protective strategies, as a real molecular pathophysiologically driven therapeutic intervention has yet to become available. While we have previously documented the expression of HVEM on leukocytes of septic mice and critically ill patients, its functional role in shock/sepsis-induced ALI has not yet been studied. Inasmuch; a murine model of indirect ALI (iALI) was induced by hemorrhagic shock (HEM) followed by cecal ligation and puncture (CLP), septic challenge and HVEM-siRNA or PBS was administrated by intra-tracheal instillation 2 hours after hemorrhage to determine the role of HVEM in the development of experimental iALI. Read More

J Comput Assist Tomogr 2018 Dec 7. Epub 2018 Dec 7.

Northwell Health Thoracic Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.

Objective: The aim of this study was to determine the average effective radiation dose and feasibility of ultralow dose dynamic expiratory computed tomography (CT) for evaluation of tracheomalacia (ULD) and to evaluate factors that impact image quality.

Methods: This is a retrospective study of 64 consecutive patients from September to October 2016 for the evaluation of tracheomalacia. All studies were performed with routine inspiration chest CT followed by ULD z(kilovoltage peak (kVp) 80, 100, or 120 and fixed milliamperage 10) or typical dose CT (TD) (kVp 100 or 120 with automated milliamperage) dynamic expiration CT. Read More

BMJ Open 2018 Dec 6;8(12):e023374. Epub 2018 Dec 6.

Department of Anesthesiology, Peking University Third Hospital, Beijing, China.

Objectives: Unrecognised malposition of the endotracheal tube can lead to severe complications in patients under general anaesthesia. The purpose of this study was to verify the feasibility of using ultrasound to measure the distance between the upper edge of saline-inflated cuff and the vocal cords.

Design: Prospective case-control study. Read More

Ann Thorac Surg 2018 Dec 7. Epub 2018 Dec 7.

Thoracic Surgery Department, Hospital Universitari la Ribera. Alzira (Spain).

We communicate the first reported application of video-assisted thoracic surgery for early repair of a post-intubation tracheal laceration. The patient was a 60-year-old male. After an initial unsuccessful approach with conservative measures, surgical repair was indicated. Read More

Microb Pathog 2018 Dec 5. Epub 2018 Dec 5.

Division of Pathology, ICAR- Indian Veterinary Research Institute, Bareilly, Izatnagar, 243 122, U.P, India. Electronic address:

The aim of the present study was to pathological and molecular investigation of porcine sapelovirus (PSV) in naturally infected Indian pigs of various age groups. Eight samples (16%) out of 49 necropsied animals were positive for PSV on the basis of pathological and molecular investigation. Major lesions of PSV positive cases were thickening and clouding of meninges, congestion in brain, severe to moderate congestion in lungs along with froathy exudates in trachea, thickening of intestinal mucosa, especially mucosal folds of ileum. Read More

Dev Biol 2018 Dec 4. Epub 2018 Dec 4.

European Molecular Biology Laboratory (EMBL), Director's Research Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany; Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences.

The terminal cells of the tracheal epithelium in Drosophila melanogaster are one of the few known cell types that undergo subcellular morphogenesis to achieve a stable, branched shape. During the animal's larval stages, the cells repeatedly sprout new cytoplasmic processes. These grow very long, wrapping around target tissues to which the terminal cells adhere, and are hollowed by a gas-filled subcellular tube for oxygen delivery. Read More

Burns 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatrics Otolaryngology Head & Neck Surgery, Princess Margaret Hospital for Children, Roberts Road, Subiaco, Western Australia 6008, Australia; Murdoch ENT, Wexford Medical Centre, St John of God Hospital (Murdoch), Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch, Western Australia 6150, Australia; School of Surgery, University of Western Australia, Stirling Highway, Crawley, Perth, Western Australia 6009, Australia; St John of God Hospital (Murdoch), Wexford Medical Center, Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch 6150, Western Australia, Australia.

Objective: To review and discuss the existing research on the pathophysiology, impact and management of inhalational injury on the larynx and lower respiratory tract.

Data Sources: A literature search was conducted on the PubMed, MedLine, Embase, Web of Science and Google Scholar databases based on the keywords "airway burn", "inhalational injury" and "larynx".

Review Methods: Inclusion criteria included English language studies containing original and review data on airway injury. Read More

Vet Anaesth Analg 2018 Aug 30. Epub 2018 Aug 30.

School of Veterinary Medicine, University of Bristol, Langford, Bristol, UK.

Objective: To assess the sedative effects, propofol sparing properties and impact on quality of induction and intubation of intravenous (IV) medetomidine and midazolam administered consecutively at different doses compared to medetomidine alone in healthy dogs for premedication.

Study Design: Prospective, randomized, blinded, clinical study.

Animals: A total of 40 adult healthy client owned dogs, weighing 18 ± 7 kg (mean ± standard deviation). Read More

J Pediatr Surg 2018 Oct 30. Epub 2018 Oct 30.

Department of Cardiothoracic Surgery, Great Ormond Street Hospital for Children, London, UK. Electronic address:

Objectives: Pediatric patients born with single functional lung can be associated with symptomatic airway abnormalities. Management of such patients is not only technically demanding but is also ethically challenging. This study reports our experience of managing symptomatic airway abnormalities in pediatric patients with congenital single functional lung. Read More

Am J Emerg Med 2018 Oct 16. Epub 2018 Oct 16.

Department of Emergency Medicine, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415, United States of America; Department of Emergency Medicine, University of Minnesota Medical School, 717 Delaware Street SE, Suite 508, Minneapolis, MN 55414, United States of America. Electronic address:

Study Objectives: Direct laryngoscopy (DL) is the traditional approach for emergency intubation but video laryngoscopy (VL) is gaining popularity. Some studies have demonstrated higher first-attempt success with VL, particularly in difficult airways. In real-world settings, physicians choose whether or not to view the video screen when utilizing VL devices for tracheal intubation. Read More

BMC Vet Res 2018 Dec 10;14(1):391. Epub 2018 Dec 10.

Department of Ecosystem and Public Health, Faculty of Veterinary Medicine, University of Calgary, Health Research Innovation Center 2C53, 3330 Hospital Drive NW, Calgary, AB, T2N 4N1, Canada.

Background: Infectious bronchitis virus (IBV) is one of the leading causes of mortality and morbidity in chickens. There are numerous serotypes and variants, which do not confer cross protection resulting in failure of currently used IBV vaccines. Although variant IBV isolates with major genetic differences have been subjected to comparative studies, it is unknown whether minor genetic differences in IBV variants within a serotype are different in terms of pathogenesis and eliciting host responses. Read More

PLoS One 2018 6;13(12):e0207611. Epub 2018 Dec 6.

Asia-Pacific Centre for Animal Health, Melbourne Veterinary School, Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria, Australia.

Infectious laryngotracheitis (ILT) is an upper respiratory tract disease of chickens that is caused by infectious laryngotracheitis virus (ILTV), an alphaherpesvirus. This disease causes significant economic loses in poultry industries worldwide. Despite widespread use of commercial live attenuated vaccines, many poultry industries continue to experience outbreaks of disease caused by ILTV. Read More

J Biomed Mater Res B Appl Biomater 2018 Dec 6. Epub 2018 Dec 6.

Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, 15261.

Tracheal stenting currently using non-degradable stents is commonplace for treatment of trauma, prolonged intubation related adult airway obstructions, and pediatric patients-associated tracheal stenosis conditions. Degradable tracheal stent placement will avoid complications of stent removal and restenosis. Widespread reports exist on degradable magnesium alloys success for orthopedic and cardiovascular applications but none to date for intra tracheal use. Read More

Biofactors 2018 Dec 6. Epub 2018 Dec 6.

Lung Inflammatory Diseases Research Center, Department of Physiology, Ardabil University of Medical Sciences, Ardabil, Iran.

The present study aimed to investigate the role of microRNA-146a and its adapter proteins [interleukin-1 receptor-associated kinase 1 (IRAK1) and tumor necrosis factor (TNF) receptor-associated factor 6 (TRAF6)] in the pathogenesis of ovalbumin (OVA)-sensitized rats in association with the diet-induced obesity condition. Twenty male Wistar rats were divided into four groups: control with normal diet (ND), OVA-sensitized with normal diet (S + ND), high-fat diet (HFD), and OVA-sensitized with high-fat diet (S + HFD). All the animals were fed for 8 weeks with standard pelts or high-fat diet, and were then sensitized and challenged with OVA or saline for another 4 weeks. Read More