49,590 results match your criteria Trachea Stenosis


An In-depth Perspective of Aortic Arch Branching in Fetal Vascular Rings Using Spatiotemporal Image Correlation Combined With High-definition Flow Imaging: Report of 4 Cases.

J Ultrasound Med 2018 Dec 11. Epub 2018 Dec 11.

Pediatric Cardiology, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan.

On the basis of 2-dimensional fetal echocardiographic findings, we investigated 4 different fetal vascular ring cases using spatiotemporal image correlation (STIC) combined with high-definition (HD) flow imaging. An in-depth 3-dimensional perspective of aortic arch branching (ie, the brachiocephalic arteries) was created by application of glass body and HDlive flow rendering algorithms (GE Healthcare, Zipf, Austria). Additionally, complete (U- or O-shaped) or incomplete (C-shaped) vascular rings were clearly differentiated in utero, and articulations around the trachea and esophagus were more easily imaged. Read More

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December 2018

Complete Genomic Sequences of Highly Pathogenic H5N1 Avian Influenza Viruses Obtained Directly from Human Autopsy Specimens.

Microbiol Resour Announc 2018 Dec 6;7(22). Epub 2018 Dec 6.

Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

The complete genomic sequences of H5N1 highly pathogenic avian influenza (HPAI) viruses were directly obtained from lung, trachea, and colon tissues and an intestinal fecal sample of a patient by using the next-generation sequencing technique. This is the first report on complete H5N1 viral genomes from human autopsy specimens. Read More

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December 2018

Feasibility of On-table Extubation After Cardiac Surgery with Cardiopulmonary Bypass: A Randomized Clinical Trial.

Anesth Pain Med 2018 Oct 24;8(5):e80158. Epub 2018 Sep 24.

Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Background: The use of short-acting anesthetics, muscle relaxation, and anesthesia depth monitoring allows maintaining sufficient anesthesia depth, fast recovery, and extubation of the patients in the operating room (OR). We evaluated the feasibility of extubation in the OR in cardiac surgery.

Methods: This clinical trial was performed on 100 adult patients who underwent elective noncomplex cardiac surgery using cardiopulmonary bypass. Read More

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October 2018

A Large Substernal Goiter that Extended to Both Sides of the Thorax.

Case Rep Surg 2018 5;2018:6107982. Epub 2018 Nov 5.

Department of Surgery, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan.

Most substernal goiters can be managed through the transcervical approach, but a sternotomy is required in some cases. This report is about a large substernal goiter, which was resected via a transcervical and full sternotomy approach. The patient was a 57-year-old female, who visited our hospital for surgical treatment for a large substernal goiter. Read More

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November 2018

[Long-term oucomes of tracheal transplantation: success and unsolved problems].

Khirurgiia (Mosk) 2018 (11):11-19

Sechenov First Moscow State Medical University, Moscow, Russia.

Aim: To analyze long-term outcomes of tracheal transplantation.

Material And Methods: There were 1128 patients with cicatricial tracheal stenosis who have been operated at the Petrovsky Russian Research Center for Surgery and the Sechenov First Moscow State Medical University for the period 1963-2015.

Results: Operations have become safer. Read More

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January 2018

Ultralow Dose Dynamic Expiratory Computed Tomography for Evaluation of Tracheomalacia.

J Comput Assist Tomogr 2018 Dec 7. Epub 2018 Dec 7.

Northwell Health Thoracic Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY.

Objective: The aim of this study was to determine the average effective radiation dose and feasibility of ultralow dose dynamic expiratory computed tomography (CT) for evaluation of tracheomalacia (ULD) and to evaluate factors that impact image quality.

Methods: This is a retrospective study of 64 consecutive patients from September to October 2016 for the evaluation of tracheomalacia. All studies were performed with routine inspiration chest CT followed by ULD z(kilovoltage peak (kVp) 80, 100, or 120 and fixed milliamperage 10) or typical dose CT (TD) (kVp 100 or 120 with automated milliamperage) dynamic expiration CT. Read More

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December 2018

Pathological and molecular investigation of porcine sapelovirus infection in naturally affected Indian pigs.

Microb Pathog 2018 Dec 5. Epub 2018 Dec 5.

Division of Pathology, ICAR- Indian Veterinary Research Institute, Bareilly, Izatnagar, 243 122, U.P, India. Electronic address:

The aim of the present study was to pathological and molecular investigation of porcine sapelovirus (PSV) in naturally infected Indian pigs of various age groups. Eight samples (16%) out of 49 necropsied animals were positive for PSV on the basis of pathological and molecular investigation. Major lesions of PSV positive cases were thickening and clouding of meninges, congestion in brain, severe to moderate congestion in lungs along with froathy exudates in trachea, thickening of intestinal mucosa, especially mucosal folds of ileum. Read More

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December 2018

Single-cell branching morphogenesis in the Drosophila trachea.

Authors:
Benedikt T Best

Dev Biol 2018 Dec 4. Epub 2018 Dec 4.

European Molecular Biology Laboratory (EMBL), Director's Research Unit, Meyerhofstr. 1, 69117 Heidelberg, Germany; Collaboration for joint PhD degree between EMBL and Heidelberg University, Faculty of Biosciences.

The terminal cells of the tracheal epithelium in Drosophila melanogaster are one of the few known cell types that undergo subcellular morphogenesis to achieve a stable, branched shape. During the animal's larval stages, the cells repeatedly sprout new cytoplasmic processes. These grow very long, wrapping around target tissues to which the terminal cells adhere, and are hollowed by a gas-filled subcellular tube for oxygen delivery. Read More

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December 2018

Inhalational injury and the larynx: A review.

Burns 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatrics Otolaryngology Head & Neck Surgery, Princess Margaret Hospital for Children, Roberts Road, Subiaco, Western Australia 6008, Australia; Murdoch ENT, Wexford Medical Centre, St John of God Hospital (Murdoch), Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch, Western Australia 6150, Australia; School of Surgery, University of Western Australia, Stirling Highway, Crawley, Perth, Western Australia 6009, Australia; St John of God Hospital (Murdoch), Wexford Medical Center, Suite 17-18, Level 1, 3 Barry Marshall Parade, Murdoch 6150, Western Australia, Australia.

Objective: To review and discuss the existing research on the pathophysiology, impact and management of inhalational injury on the larynx and lower respiratory tract.

Data Sources: A literature search was conducted on the PubMed, MedLine, Embase, Web of Science and Google Scholar databases based on the keywords "airway burn", "inhalational injury" and "larynx".

Review Methods: Inclusion criteria included English language studies containing original and review data on airway injury. Read More

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December 2018

Evaluation of magnesium alloys for use as an intraluminal tracheal for pediatric applications in a rat tracheal bypass model.

J Biomed Mater Res B Appl Biomater 2018 Dec 6. Epub 2018 Dec 6.

Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, 15261.

Tracheal stenting currently using non-degradable stents is commonplace for treatment of trauma, prolonged intubation related adult airway obstructions, and pediatric patients-associated tracheal stenosis conditions. Degradable tracheal stent placement will avoid complications of stent removal and restenosis. Widespread reports exist on degradable magnesium alloys success for orthopedic and cardiovascular applications but none to date for intra tracheal use. Read More

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December 2018
2 Reads

Co-localization of Middle East respiratory syndrome coronavirus (MERS-CoV) and dipeptidyl peptidase-4 in the respiratory tract and lymphoid tissues of pigs and llamas.

Transbound Emerg Dis 2018 Dec 6. Epub 2018 Dec 6.

UAB, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.

The present study investigated the co-localization of the Middle East respiratory syndrome coronavirus (MERS-CoV) and its receptor dipeptidyl peptidase-4 (DPP4) across respiratory and lymphoid organs of experimentally MERS-CoV infected pigs and llamas by immunohistochemistry (IHC). Also, scanning electron microscopy (SEM) was performed to assess the ciliary integrity of respiratory epithelial cells in both species. In pigs, on day 2 post-inoculation (p. Read More

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December 2018

Aortopexy for tracheomalacia via a suprasternal incision.

J Pediatr Surg 2018 Nov 7. Epub 2018 Nov 7.

Department of Paediatric Surgery, Evelina London Children's Hospital, Lambeth, London, UK. Electronic address:

Aim: Tracheomalacia is flaccidity of the tracheal wall leading to tracheal collapse, particularly on expiration. When severe it can warrant surgical intervention. Aortopexy is one surgical option and has been described using a variety of approaches. Read More

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November 2018
1 Read

Effect of Kaempferol on Cyclooxygenase 2 (Cox2) and Cytosolic Phospholipase A2 (cPLA2) Protein Expression in BALB/c Mice.

Iran J Allergy Asthma Immunol 2018 Oct 14;17(5):428-435. Epub 2018 Oct 14.

Department of Animal Biotechnology, College of Agriculture and Life Sciences, Chonbuk National University, Jeonju, Republic of Korea.

Kaempferol, a phytochemical found in many edible plants, is known to alleviate diseases such as cancer, allergy, and inflammation. The objective of this study was to investigate whether kaempferol could reduce omega-6 and ovalbumin-mediated allergic reactions at lung and trachea in BALB/c mice. Mice were allocated into five groups: 1) control group (CON); 2) positive control group with orally administration of omega-6 (POS); 3) bovine serum albumin (BSA) sensitization group (with BSA injection and ovalbumin inhalation); 4) BSA+K10 group: BSA injection, 10 μg/g of kaempferol administration and ovalbumin inhalation; and 5) BSA+K20 group: BSA injection, 20 μg/g of kaempferol administration and ovalbumin inhalation. Read More

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October 2018

Host immune responses of pigeons infected with Newcastle disease viruses isolated from pigeons.

Microb Pathog 2018 Nov 30;127:131-137. Epub 2018 Nov 30.

College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China; National and Regional Joint Engineering Laboratory for Medicament of Zoonosis Prevention and Control, China; Key Laboratory of Animal Vaccine Development, Ministry of Agriculture, China; Key Laboratory of Zoonosis Prevention and Control of Guangdong Province, China. Electronic address:

Newcastle disease (ND), affecting over 250 bird species, is caused by the Newcastle disease virus (NDV). ND is one of the leading causes of morbidity and mortality in pigeons. Most studies investigating NDV in pigeons have focused on the epidemiology and pathogenicity of the virus. Read More

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November 2018
3 Reads

Reconstruction of a Posterior Tracheal Wall Defect With a Myocutaneous Pectoralis Major Flap After Salvage Cervical Exenteration for a Squamous Carcinoma of the Upper Third of the Esophagus.

Plast Surg Nurs 2018 Oct/Dec;38(4):162-165

Enrique Salmerón-González, MD, Plastic Surgeon, Plastic and Reconstructive Surgery Department, University and Polytechnic Hospital La Fe, Valencia, Spain. Elena García-Vilariño, MD, Plastic Surgeon, Plastic and Reconstructive Surgery Department, University and Polytechnic Hospital La Fe, Valencia, Spain. Pedro A. Antolin-Santamaria, MD, Plastic Surgeon, Plastic and Reconstructive Surgery Department, University and Polytechnic Hospital La Fe, Valencia, Spain. Alberto Sanchez-Garcia, MD, Plastic Surgeon, Plastic and Reconstructive Surgery Department, University and Polytechnic Hospital La Fe, Valencia, Spain. Alfonso A. Valverde-Navarro, PhD, Director, Department of Human Anatomy and Embryology, University of Valencia, Spain.

In this article, we describe the case of a 59-year-old patient suffering from a squamous cell carcinoma affecting the upper third of the esophagus, treated with a cervical exenteration with extended resection of the posterior wall of the trachea, which was reconstructed with a gastric tube transposition and a myocutaneous pectoralis major flap for coverage of the gastropharyngeal anastomosis and stabilization of the posterior tracheal wall. Also, a review of literature regarding posterior tracheal wall reconstruction is performed. Read More

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December 2018
3 Reads

Impact of stainless-steel welding fumes on proteins and non-coding RNAs regulating DNA damage response in the respiratory tract of Sprague-Dawley rats.

J Toxicol Environ Health A 2018 Dec 3:1-15. Epub 2018 Dec 3.

a Department of Biochemistry and Biotechnology, Faculty of Science , Annamalai University , Annamalainagar , TN , India.

Substantial evidence has established the negative impact of inhalation exposure to welding fumes on respiratory functions. The aim of the present study was to investigate the effect of welding fume inhalation on expression of molecules that function as sensors, transducers and effectors of DNA damage response (DDR) in the respiratory tract of male Sprague-Dawley rats. Animals were exposed to 50 mg/m stainless steel welding fumes for 1 h/d for 4, 8, and 12 weeks, respectively. Read More

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December 2018

Preliminary study on application of augmented reality visualization in robotic thyroid surgery.

Ann Surg Treat Res 2018 Dec 26;95(6):297-302. Epub 2018 Nov 26.

Department of Biomedical Engineering, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Purpose: Increased robotic surgery is attended by increased reports of complications, largely due to limited operative view and lack of tactile sense. These kinds of obstacles, which seldom occur in open surgery, are challenging for beginner surgeons. To enhance robotic surgery safety, we created an augmented reality (AR) model of the organs around the thyroid glands, and tested the AR model applicability in robotic thyroidectomy. Read More

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December 2018
4 Reads

Polypoidal trachea- A clinician's predicament.

Am J Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Otorhinolaryngology & Head and Neck surgery, All India Institute of Medical Sciences, New Delhi 110029, India. Electronic address:

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November 2018
2 Reads

Detailed Fetal Anatomic Ultrasound Examination: Effect of the 2014 Consensus Report on a Tertiary Referral Center.

Ultrasound Q 2018 Dec 3. Epub 2018 Dec 3.

Department of Radiology, University of California, San Diego, San Diego, CA.

This study evaluates the impact of extended cardiac views on examination time, repeat imaging, and anomaly detection before and after implementation of 76811 guidelines (American Institute of Ultrasound in Medicine Consensus 2014). It is a retrospective study of singleton pregnancies undergoing detailed ultrasound imaging at 18 weeks' gestation or greater before and after the protocol change in an academic, tertiary care fetal center. Views required prior to 2014: 4-chamber, left outflow tract, right outflow tract. Read More

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December 2018
2 Reads

Results of a surgical cricothyrotomy workshop with a pig trachea model.

Rev Esp Anestesiol Reanim 2018 Dec 1. Epub 2018 Dec 1.

Hospital Universitari Joan XXIII, Tarragona, España.

Background: The latest Difficult Airway Society (DAS) guidelines recommend that all anaesthesiologists should to be trained in the performing of a surgical cricothyrotomy (CtQ). The aim of this study was to analyse the learning results of a CtQ workshop by assessing the success rate and time to perform CtQ on a porcine tracheal model.

Material And Methods: A workshop was designed in which each student completed a questionnaire with demographic data and theoretical knowledge about surgical approaches of airway. Read More

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December 2018
1 Read

Predictors of nodal metastasis and prognostic significance of lymph node ratio and total lymph node count in tracheobronchial adenoid cystic carcinoma.

Cancer Manag Res 2018 19;10:5919-5925. Epub 2018 Nov 19.

Department of Thoracic Surgery, Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China,

Purpose: To identify potential risk factors of lymph node metastasis and to verify the prognostic significance of the lymph node ratio (LNR) and the total number of lymph nodes examined (NNE) in tracheobronchial adenoid cystic carcinoma (ACC) patients, using a large population-based database.

Patients And Methods: From Surveillance, Epidemiology, and End Results database, we identified 263 patients with tracheobronchial ACC in whom complete lymph node data could be obtained. Logistic regression analysis was performed to determine predictive factors of nodal metastasis. Read More

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November 2018
1 Read

Devising negative pressure within intercuff space reduces microaspiration.

BMC Anesthesiol 2018 Dec 3;18(1):181. Epub 2018 Dec 3.

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea.

Background: Microaspiration past the tracheal tube cuffs causes ventilator-associated pneumonia. The objective of the current study was to evaluate whether creating negative pressure between the tracheal double cuffs could block the fluid passage past the tracheal tube cuffs.

Methods: A new negative pressure system was devised between the double cuffs through a suction hole in the intercuff space. Read More

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December 2018

Rosai-Dorfman disease of the trachea: an extremely rare benign tumor.

Asian Cardiovasc Thorac Ann 2018 Dec 3:218492318817677. Epub 2018 Dec 3.

3 Department of Cardiothoracic Surgery, Apollo Hospital, Chennai, India.

Rosai-Dorfman disease or sinus histiocytosis is a nonmalignant disease chiefly presenting as a painless cervical lymphadenopathy, although extranodal involvement is also frequent. Involvement of the tracheobronchial tree is extremely rare, and there are no clear guidelines on management. Rosai-Dorfman disease usually presents as a tracheal tumor, although it may also present with extraluminal compression. Read More

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December 2018
1 Read

Data Set for the Reporting of Carcinomas of the Hypopharynx, Larynx, and Trachea: Explanations and Recommendations of the Guidelines From the International Collaboration on Cancer Reporting (ICCR).

Arch Pathol Lab Med 2018 Nov 30. Epub 2018 Nov 30.

From the Department of Cellular Pathology, University of Liverpool, Liverpool, United Kingdom (Dr Helliwell); the Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, Missouri (Dr Chernock); ANU College of Health and Medicine, Anatomical Pathology, ACT Pathology, Canberra Hospital, Woden, Australia (Dr Dahlstrom); Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia (Drs Gale and Zidar); the Department of Pathology, Michigan Medicine - University of Michigan, Ann Arbor (Dr McHugh); the Department of Anatomic Pathology, Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada (Dr Perez-Ordoñez); the Department of ENT-Head and Neck Surgery, University Hospital Aintree, Liverpool, United Kingdom (Dr Roland); and the Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills (Dr Thompson).

The International Collaboration on Cancer Reporting is a nonprofit organization whose mission is to develop evidence-based, universally available surgical pathology reporting data sets. Standardized pathologic reporting for cancers facilitates improved communication for patient care and prognosis and the comparison of data between countries to progressively improve clinical outcomes. Laryngeal cancers are often accompanied by significant morbidity, although surgical advances (such as transoral endoscopic laser microresection and transoral robotic surgery) provide new alternatives. Read More

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November 2018
5 Reads

Percutaneous Lauromacrogol Foam Sclerotherapy for the Treatment of Acute Airway Compression Caused by Lymphatic Malformations in Infants.

Biomed Res Int 2018 18;2018:3878960. Epub 2018 Oct 18.

Department of Radiology, Wuhan Children Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China.

Management of LMs still remains a challenge especially for those suffering from complications such as acute airway compression. In this study, we retrospectively evaluated the efficacy and safety of percutaneous lauromacrogol foam sclerotherapy for the patients with acute airway compression caused by lymphatic malformations (LMs) in infants. Five cases of infants with acute airway compression caused by LMs were treated with lauromacrogol foam sclerotherapy in the radiology department from February 2013 to August 2015 at Wuhan Medical and Healthcare Center for Women and Children, China. Read More

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October 2018
1 Read

A PEG-Lysozyme hydrogel harvests multiple functions as a fit-to-shape tissue sealant for internal-use of body.

Biomaterials 2018 Nov 2;192:392-404. Epub 2018 Nov 2.

Key Laboratory for Ultrafine Materials of Ministry of Education, School of Material Science and Engineering, East China University of Science and Technology, Shanghai 200237, China. Electronic address:

In situ formation of surgical sealants to stop internal fluids leakage is more attractive compared to the traditional suture or staple. However, commercial sealants have weak points in tissue adhesive, cell affinity, antibacterial etc., which make them remain suboptimal for internal use of body. Read More

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November 2018

Usefulness of the Universal Adapter for Smartphones in a Mannequin Study.

Tokai J Exp Clin Med 2018 Dec 20;43(4):139-142. Epub 2018 Dec 20.

Department of Anesthesiology, Hachioji-hospital, Tokai University School of Medicine, 1838 Ishikawamachi, Hachioji, Tokyo 192-0032, Japan:

Objective: Because of the shape of a double-lumen tube (DLT), it is more difficult to use for intubation than an ordinary endotracheal tube. We prospectively investigated the usefulness of the Airtraq DL attached to the Universal Adapter for Smartphones for DLT intubation.

Method: At Tokai University Hachioji Hospital, anesthesiologists with ≥ 5 years' clinical experience intubated a tracheal intubation training mannequin with DLTs using the Airtraq DL (Airtraq-alone phase) and the Airtraq DL attached to the Universal Adapter for Smartphones (adapter phase), and the time required was measured. Read More

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December 2018

[Effects of different time of cryoablation on the proliferation of airway traumatic granuloma and its mechanism in rabbits].

Zhonghua Yi Xue Za Zhi 2018 Nov;98(44):3587-3591

Department of Pulmonary and Critical Care Medicine, Fujian Provincial Hospital, Fujian Medical University, Fuzhou 350001, China.

To investigate the effect of different cryoablation time on tracheal traumatic granulation formation and its mechanism. A total of 32 rabbits were randomly assigned into four groups (A-D). Group A underwent tracheotomy alone. Read More

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November 2018
3 Reads

Helical multi-detector CT scan as a tool for diagnosing tracheomalacia in children.

Pediatr Pulmonol 2018 Nov 28. Epub 2018 Nov 28.

Second Department of Radiology, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.

Background/aims: Tracheomalacia (TM) is not an unusual diagnosis in pediatric respiratory clinics. The aim of this study was to assess the accuracy of paired static end-inspiratory/end-expiratory helical multi-detector CT scan (MDCT) in detecting TM.

Methods: FB was performed in 28 children suspected of TM on the grounds of presence of recurrent episodes of vibrating cough and a need for more specific diagnostic information. Read More

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November 2018

Long-term use of Le Fort I osteotomy for the management of nasopharyngeal rhinosporidiosis: A case series.

Ear Nose Throat J 2018 Oct-Nov;97(10-11):E36-E43

Department of Craniofacial Surgery, Nitte Meenakshi Institute of Craniofacial Surgery, Deralakatte, Mangalore, Karnataka, India.

Rhinosporidiosis is a rare, chronic, granulomatous infection of the mucous membranes that mainly involves the nose and nasopharynx; it occasionally involves the pharynx, conjunctiva, larynx, trachea and, rarely, the skin. The characteristic clinical features of this disease include the formation of painless polyps in the nasal mucosa or the nasopharynx that bleed easily on touch. At our center, excision of the lesion with a Le Fort I osteotomy is carried out in patients (1) in whom two or more previous attempts at excision of biopsy-proven rhinosporidiosis arising from the nasal mucosa was carried out or (2) in whom the rhinosporidiosis arises from the nasophayrngeal mucosa and/or extranasal sites. Read More

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November 2018
2 Reads

Particle deposition in the human lung: Health implications of particulate matter from different sources.

Environ Res 2018 Nov 14;169:237-245. Epub 2018 Nov 14.

Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.

Although ambient particulate matter or particles have been found to be associated with morbidity and mortality all over the world, specific health effects of particles from different sources need further elucidation. The objective of this work is to predict the deposition of particles from different sources in the human lung. The whole lung, consisting of 24 generations of branches from trachea to alveoli, was approximated using a one-dimensional lumped "trumpet" model with a variable cross-sectional area. Read More

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November 2018

sp. n., the first subterranean species of centipede from southern China (Lithobiomorpha, Lithobiidae).

Zookeys 2018 8(795):83-91. Epub 2018 Nov 8.

Guizhou Institute of Biology, Guiyang, Guizhou 550001, PR China.

(Lithobiomorpha: Lithobiidae) was recently discovered from the Cave of the brickyard of Gaofeng village, in the Guizhou Province, southwest China, and it is described here. Morphologically the new species is similar to (Trozina>, 1894) from north-western China. The new species can be easily distinguished from those by the trachea connected to the valve of the TIII clearly visible from the dorsal side, the absence of ocelli on each side of the cephalic plate, the DaC spine being only present on the XIII-XV legs. Read More

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November 2018
4 Reads

Co-signaling receptors regulate T-cell plasticity and immune tolerance.

Front Biosci (Landmark Ed) 2019 01 1;24:96-132. Epub 2019 Jan 1.

Centers for Metabolic Disease Research, Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 19140, U.S.A.

We took an experimental database mining analysis to determine the expression of 28 co-signaling receptors in 32 human tissues in physiological/pathological conditions. We made the following significant findings: co-signaling receptors are differentially expressed in tissues; heart, trachea, kidney, mammary gland and muscle express co-signaling receptors that mediate CD4T cell functions such as priming, differentiation, effector, and memory; urinary tumor, germ cell tumor, leukemia and chondrosarcoma express high levels of co-signaling receptors for T cell activation; expression of inflammasome components are correlated with the expression of co-signaling receptors; CD40, SLAM, CD80 are differentially expressed in leukocytes from patients with trauma, bacterial infections, polarized macrophages and in activated endothelial cells; forward and reverse signaling of 50% co-inhibition receptors are upregulated in endothelial cells during inflammation; and STAT1 deficiency in T cells upregulates MHC class II and co-stimulation receptors. Our results have provided novel insights into co-signaling receptors as physiological regulators and potentiate identification of new therapeutic targets for the treatment of sterile inflammatory disorders. Read More

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January 2019
1 Read

CT evaluation of aberrant right subclavian artery: anatomy and clinical implications.

Cardiol Young 2018 Nov 23:1-5. Epub 2018 Nov 23.

Department of Radiology and Diagnostic Imaging,John Paul II Hospital,Krakow,Poland.

PurposeThe aim of the study was to perform CT angiography-based evaluation of aberrant right subclavian artery prevalence, anatomy, and its influence on clinical symptoms.

Methods: A total of 6833 patients who underwent 64-slice or dual-source CT angiography and those who revealed aberrant right subclavian artery underwent evaluation of its anatomy and were interviewed for the presence of clinical symptoms.

Results: Aberrant right subclavian artery was found in 32 (0. Read More

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November 2018
3 Reads

Giant adenomatous thyroid nodule compressing the trachea.

J Gen Fam Med 2018 Nov 29;19(6):219-220. Epub 2018 Aug 29.

Department of General Internal Medicine Mitoyo General Hospital Kanonji Japan.

This paper details the clinical history and management of a 20-year-old male patient who presented with a 2-year history of a neck swelling which was gradually enlarging during the last 3 months. The tumor was histologically diagnosed as an adenomatous nodule of the thyroid gland. Read More

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November 2018
3 Reads

BronchoX: bronchoscopy exploration software for biopsy intervention planning.

Healthc Technol Lett 2018 Oct 18;5(5):177-182. Epub 2018 Sep 18.

Computer Vision Center, Autonomous University of Barcelona, Bellaterra 08193, Spain.

Virtual bronchoscopy (VB) is a non-invasive exploration tool for intervention planning and navigation of possible pulmonary lesions (PLs). A VB software involves the location of a PL and the calculation of a route, starting from the trachea, to reach it. The selection of a VB software might be a complex process, and there is no consensus in the community of medical software developers in which is the best-suited system to use or framework to choose. Read More

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October 2018

Robust reconstruction of local optic axis orientation with fiber-based polarization-sensitive optical coherence tomography.

Biomed Opt Express 2018 Nov 15;9(11):5437-5455. Epub 2018 Oct 15.

Optical + Biomedical Engineering Laboratory, Department of Electrical, Electronic and Computer Engineering, The University of Western Australia, Perth, WA 6009, Australia.

It is challenging to recover local optic axis orientation from samples probed with fiber-based polarization-sensitive optical coherence tomography (PS-OCT). In addition to the effect of preceding tissue layers, the transmission through fiber and system elements, and imperfect system alignment, need to be compensated. Here, we present a method to retrieve the required correction factors from measurements with depth-multiplexed PS-OCT, which accurately measures the full Jones matrix. Read More

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November 2018
2 Reads

A Hippo-like Signaling Pathway Controls Tracheal Morphogenesis in Drosophila melanogaster.

Dev Cell 2018 Dec 25;47(5):564-575.e5. Epub 2018 Oct 25.

Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia; Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC 3010, Australia; Department of Pathology, University of Melbourne, Parkville, VIC 3010, Australia; Department of Anatomy and Developmental Biology and Biomedicine Discovery Institute, Monash University, Clayton, VIC 3168, Australia. Electronic address:

Hippo-like pathways are ancient signaling modules first identified in yeasts. The best-defined metazoan module forms the core of the Hippo pathway, which regulates organ size and cell fate. Hippo-like kinase modules consist of a Sterile 20-like kinase, an NDR kinase, and non-catalytic protein scaffolds. Read More

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December 2018
3 Reads

Prenatal diagnosis of cervical masses by magnetic resonance imaging and 3D virtual models: perinatal and long-term follow-up outcomes.

J Matern Fetal Neonatal Med 2018 Nov 20:1-9. Epub 2018 Nov 20.

c Department of Obstetrics, Paulista School of Medicine , Federal University of São Paulo (EPM-UNIFESP) , São Paulo , Brazil.

Objective: To assess perinatal and long-term follow-up outcomes of fetal cervical masses diagnosed by three-dimensional (3D) magnetic resonance imaging (MRI) and 3D virtual models.

Methods: This retrospective cohort study evaluated 15 pregnant women (age, 21-38 years) at 29-40 weeks of singleton gestation, whose fetuses exhibited congenital oral and cervical masses. These women were referred to our facility because of suspected fetal malformations on routine obstetric ultrasound, and the cases were confirmed, excluded, or complemented by MRI. Read More

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November 2018
2 Reads

Tetralogy of Fallot With Right Aortic Arch and Retro-Aortic Innominate Vein.

Front Pediatr 2018 2;6:331. Epub 2018 Nov 2.

East Midlands Congenital Heart Center, Glenfield Hospital, Leicester, United Kingdom.

Right aortic arch (RAA) and retro-aortic innominate vein are rare vascular anomalies. Diagnosis of these anatomical variations can be achieved using fetal echocardiography, post-natal echocardiography, and computed tomography scan. RAA can form a vascular ring when associated with other vascular anomalies which may compress the trachea and/or esophagus. Read More

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November 2018
10 Reads

Fructose-1,6-bisphosphate aldolase encoded by a core gene of Mycoplasma hyopneumoniae contributes to host cell adhesion.

Vet Res 2018 Nov 19;49(1):114. Epub 2018 Nov 19.

Key Laboratory of Veterinary Biological Engineering and Technology of Ministry of Agriculture, Institute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.

Mycoplasma hyopneumoniae is an important respiratory pathogen that causes great economic losses to the pig industry worldwide. Although some putative virulence factors have been reported, pathogenesis remains poorly understood. Herein, we evaluated the relative abundance of proteins in virulent 168 (F107) and attenuated 168L (F380) M. Read More

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November 2018
3 Reads

An omentum-cultured 3D-printed artificial trachea: in vivo bioreactor.

Artif Cells Nanomed Biotechnol 2018 Nov 19:1-10. Epub 2018 Nov 19.

a Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, College of Medicine , Hallym University , Chuncheon , Republic of Korea.

The purpose of this study was to evaluate whether the prior implantation of a 3D-printed polycaprolactone (PCL) artificial trachea in the omentum is beneficial for revascularization of the scaffold and reduces associated complications in the reconstruction of a circumferential tracheal defect. Ten New Zealand rabbits were divided into 2 groups: (1) PCL-OC group (PCL scaffold cultured in omentum for 2 weeks before transplantation) and (2) PCL group. In the PCL-OC group, newly formed connective tissue completely covered the luminal surface of the scaffold with mild inflammation at 2 weeks postoperatively; a minor degree of stenosis was noted at 8 weeks postoperatively. Read More

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November 2018
6 Reads

Experimental animal model for assessment of tracheal epithelium regeneration.

Laryngoscope 2018 Nov 19. Epub 2018 Nov 19.

National Research Center Kurchatov Institute, Moscow, Russian Federation.

Objectives/hypothesis: To develop an experimental model in rabbits for assessment of tracheal epithelium regeneration through application of either natural or artificial polymer scaffolds.

Study Design: First, we identified the size of full-thickness mucosal defect, which does not allow self-healing (a "critical defect"), thus representing an adequate experimental model for regenerative therapy of tracheal epithelium damage. Then, two methods of polymer scaffold fixation at the site of the epithelium defect were compared: suturing and fixation with a stent. Read More

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November 2018
8 Reads

Unusual invasion of primary pulmonary adenocarcinoma in a cat.

JFMS Open Rep 2018 Jul-Dec;4(2):2055116918810897. Epub 2018 Nov 8.

Department of Clinical Sciences, Cummings School of Veterinary Medicine at Tufts University, North Grafton, MA, USA.

Case Summary: An 11-year-old female spayed domestic shorthair cat was referred to the Foster Hospital for Small Animals, USA for suspected dysautonomia based on weight loss, vomiting and referral radiographs that showed severe dilation of the esophagus, stomach and entire gastrointestinal tract. After recheck radiographs revealed a decrease in gas compared with the referral images, persistently reduced gastrointestinal motility was deemed less likely; however, cardiomegaly and a soft tissue opacity overlying the esophagus were noted. Echocardiogram identified a pulmonary mass either impinging on or invading the local organs. Read More

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November 2018
2 Reads

Traumatic Airway Injuries: Role of Imaging.

Curr Probl Diagn Radiol 2018 Oct 29. Epub 2018 Oct 29.

Department of Radiology and Department of Surgery, JPN Apex trauma Center, All India Institute of Medical Sciences, New Delhi, India.

Airway Injuries are rare but often immediately life threatening. Incidence ranges from 0.5-2 % in blunt and 1-6 % in penetrating trauma. Read More

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October 2018
3 Reads

Anatomical variations of the aortic arch branches in a sample of Chinese cadavers: embryological basis and literature review.

Interact Cardiovasc Thorac Surg 2018 Nov 15. Epub 2018 Nov 15.

Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou City, Guangdong Province, China.

Objectives: The aim of this study is to determine the incidence and explore the types of aortic arch branch variations found in our cadavers.

Methods: The types and incidence of aortic branch variations in 120 cadavers were analysed after careful dissection.

Results: One hundred and six of 120 cadavers had normal aortic arch branches and gave rise to usual branches, namely the brachiocephalic trunk, the left common carotid artery and the left subclavian artery. Read More

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November 2018
15 Reads

Near-Hangings: Epidemiology, Injuries, and Investigations.

J Trauma Acute Care Surg 2018 Nov 15. Epub 2018 Nov 15.

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, CA.

Background: Near-hangings are an infrequent cause of trauma and the optimal work-up for these patients is unclear. The study objectives were to define the epidemiology, injury patterns, and use of investigations, including CTA neck, after near-hangings.

Methods: All patients presenting to LAC+USC Medical Center (2008-2015) after near-hanging (ICD-9 E913. Read More

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November 2018
2 Reads

Bilateral Displacement of the Common Carotid Arteries by a Large Goiter.

Cureus 2018 Sep 13;10(9):e3298. Epub 2018 Sep 13.

Neurosurgery, Seattle Science Foundation, Seattle, USA.

Large goiters are less common in the developing world due to the use of iodized salt. However, these are seen occasionally. Herein, we report a case of very large goiter identified in a cadaver. Read More

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September 2018
1 Read

Augmented Reality to Localize Individual Organ in Surgical Procedure.

Healthc Inform Res 2018 Oct 31;24(4):394-401. Epub 2018 Oct 31.

Department of Biomedical Engineering, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.

Objectives: Augmented reality (AR) technology has become rapidly available and is suitable for various medical applications since it can provide effective visualization of intricate anatomical structures inside the human body. This paper describes the procedure to develop an AR app with Unity3D and Vuforia software development kit and publish it to a smartphone for the localization of critical tissues or organs that cannot be seen easily by the naked eye during surgery.

Methods: In this study, Vuforia version 6. Read More

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October 2018
2 Reads

Alpha-tocopherol potentiates the cervical resistance decreasing effects of COX-inhibitors in pregnant rats: the putative role of cyclooxygenase-2 inhibition.

J Pharmacol Exp Ther 2018 Nov 15. Epub 2018 Nov 15.

University of Szeged, Hungary

Vitamin E and their analogues as antioxidant and lipid soluble compounds can have diverse effects on the physiological processes. By binding to receptors and enzymes, they may modify the action of drugs. It has been proved that alpha-tocopherol succinate modifies the effects of β2 agonist terbutaline and cyclooxygenase (COX) inhibitors on rat trachea and myometrium. Read More

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November 2018
3 Reads