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Arch Bronconeumol 2019 Apr 18. Epub 2019 Apr 18.

Serviço de Pneumologia B, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.

Adv Exp Med Biol 2019 Apr 16. Epub 2019 Apr 16.

Department of Pneumology, School of Medicine in Katowice, Upper-Silesian Medical Center, Medical University of Silesia, Katowice, Poland.

Respiratory failure is one of the most important risk factors for diagnostic bronchofiberoscopy (BF), whereas therapeutic bronchoscopies are typically performed in intubated patients. Only a few published studies analyzed the outcomes of noninvasive mechanical ventilation (NIV)-facilitated BF. In this case series, we present our experiences with NIV-facilitated diagnostic and therapeutic BF performed in patients with respiratory failure that was associated with acute interstitial pulmonary disease, chronic obstructive pulmonary disease, cystic fibrosis exacerbation, foreign body aspiration, tracheal stenosis, pneumonia, and in a patient with a neuromuscular disease. Read More

J Am Vet Med Assoc 2019 May;254(9):1086-1093

Objective: To evaluate long-term outcomes and identify factors associated with death or the need for revision surgery in dogs with permanent tracheostomies (PTs).

Design: Retrospective cohort study.

Animals: 69 client-owned dogs that received a PT between January 2002 and June 2016 at 1 of 4 veterinary teaching hospitals. Read More

J Vis Exp 2019 Apr 1(146). Epub 2019 Apr 1.

Department of Otolaryngology Head & Neck Surgery, Nationwide Children's Hospital; Center for Regenerative Medicine, Research Institute at Nationwide Children's Hospital;

Treatment options for congenital or secondary long segment tracheal defects have historically been limited due to an inability to replace functional tissue. Tissue engineering holds great promise as a potential solution with its ability to integrate cells and signaling molecules into a 3-dimensional scaffold. Recent work with tissue engineered tracheal grafts (TETGs) has seen some success but their translation has been limited by graft stenosis, graft collapse, and delayed epithelialization. Read More

Acta Anaesthesiol Scand 2019 Apr 14. Epub 2019 Apr 14.

Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, Chelsea & Westminster Hospital, London, UK.

Background: Tracheostomy and endotracheal intubation can result in subglottic tracheal stenosis, and predisposition to keloid scar formation can increase stenosis risk after tracheal injury. This study aims to compare the incidence and severity of subglottic tracheal stenosis in keloid and non-keloid patients following iatrogenic tracheal injury, in particular tracheostomy.

Methods: From 2012 to 2017, 218 573 patients were intubated for surgery; 2276 patients received tracheostomy in People's Hospital of Zhengzhou University, China. Read More

Otolaryngol Head Neck Surg 2019 Apr 9:194599819841893. Epub 2019 Apr 9.

1 Division of Pediatric Otolaryngology-Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Objective: This study documents the growth and course of repaired complete tracheal rings over time after slide tracheoplasty.

Study Design: Case series with review.

Setting: Tertiary pediatric academic medical center. Read More

Eur Arch Otorhinolaryngol 2019 Apr 2. Epub 2019 Apr 2.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Groningen, University Medical Center Groningen (UMCG), Hanzeplein 1, PO box 30.001, 9700 RB, Groningen, The Netherlands.

Objectives: The aim of this study was to determine and compare the incidence of long- and short-term complications of percutaneous dilatation tracheotomies (PDT) and surgical tracheotomies (ST).

Design: A single-centre retrospective study.

Participants: 305 patients undergoing a tracheotomy (PDT or ST) in the University Medical Center Groningen from 2003 to 2013 were included. Read More

Oncol Lett 2019 Apr 19;17(4):3990-3996. Epub 2019 Feb 19.

Department of Respiration, Beijing Tian Tan Hospital, Capital Medical University, Beijing 100050, P.R. China.

Malignant carinal stenosis is a disease process that is not always suitable for treatment with a Y-shaped stent. When one of the main bronchi is completely obstructed and cannot be recanalized, or its distal lung tissue has lost function, inserting a Y-shaped stent is infeasible. In this complex condition, a cone-shaped stent is selected to maintain the patency of the trachea and the other main bronchus. Read More

Ann Thorac Surg 2019 Mar 27. Epub 2019 Mar 27.

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address:

Background: Removal of tumors that invade the trachea or carina often results in a massive defect that exceeds the limits of end-to-end anastomosis. The purpose of this study is to discuss the clinical value of bronchial flap for the closure of central airway defects after non-circumferential tracheal or carinal resection.

Methods: From 1990 to 2016, 73 patients underwent non-circumferential tracheal or carinal resection. Read More

Zhonghua Yi Xue Za Zhi 2019 Mar;99(12):918-922

Department of Respiratory and Critical Care Medicine, National Clinical Research Center for Respiratory Disease, Xiangya Hospital, Central South University, Changsha 410000, China.

To analyze the clinical features of primary tracheobronchial pulmonary amyloidosis (PTBA). The records of 11 patients with PTBA diagnosed by pathology from January 2002 to June 2018 in Xiangya Hospital of Central South University were retrospectively reviewed, including clinical manifestations, laboratory and imaging examination, bronchoscopic manifestations and therapies. Meanwhile, PTBA was staged based on the severity and extent of lesion under bronchoscopy. Read More

Laryngoscope 2019 Mar 25. Epub 2019 Mar 25.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.

Objectives/hypothesis: Combined anterior and posterior tracheobronchopexy is a novel surgical approach for the management of severe tracheobronchomalacia (TBM). We present our institutional experience with this procedure. Our objective was to determine the utility and safety of anterior and posterior tracheopexy in the treatment of severe TBM. Read More

Case Rep Infect Dis 2019 17;2019:8912136. Epub 2019 Feb 17.

Hunan Children's Hospital, Changsha, China.

Pulmonary artery sling is a rare cause of respiratory distress created by compression of the lower trachea and right mainstem bronchus due to an aberrant origin of the left pulmonary artery. The condition is frequently associated with recurrent respiratory infections and other congenital malformations including tracheal rings. We present the case of an infant presenting with pulmonary distress and a history of recurrent respiratory infection. Read More

Zhejiang Da Xue Xue Bao Yi Xue Ban 2018 Dec;47(6):643-650

Department of Gastroenterology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.

Objective: To evaluate the efficacy and safety of digestive tract stent implantation under direct visual endoscopy without X-ray monitoring in the treatment of digestive tract stricture.

Methods: The clinical data of patients undergoing digestive tract stent placement under direct visual endoscopy without X-ray monitoring in the First Affiliated Hospital of Zhejiang University School of Medicine from March 2003 to November 2017 were retrospectively analyzed. The process of procedures, the postoperative complications and the postoperative follow-up data were documented. Read More

Biomater Sci 2019 Apr;7(5):1863-1874

Johns Hopkins School of Medicine, 733 N Broadway, Baltimore, MD 21205, USA.

Objective: Develop a drug-eluting stent construct with a reliable drug-release profile and adequate mechanically stability for a trial in a small animal model of laryngotracheal stenosis (LTS), a debilitating pathologic narrowing of the airway leading to significant shortness of breath.

Methods: Biodegradable, biocompatible stents containing 1.0% rapamycin made of PLLA-PCL (70% Poly-l-Lactide and 30% Polycaprolactone blend) and 50 : 50 PDLGA (Poly(dl-lactide-co-glycolide)) were compared. Read More

Autops Case Rep 2019 Jan-Mar;9(1):e2018072. Epub 2019 Jan 14.

Universidade de São Paulo (USP), Hospital Universitário, Surgery Division.São Paulo, SP,Brazil.

Endotracheal intubation injuries are rare, but may be devastating-mostly among the pediatric patients or when these occur in the distal trachea. Such complications typify a therapeutic challenge, which, besides requiring intellectual and technical resources, takes a long time to reach a resolution. The authors present the case of a 15-year-old girl admitted with an abnormal state of consciousness due to diabetic ketoacidosis. Read More

Khirurgiia (Mosk) 2019(2):19-25

Vishnevsky National Medical Research Center for Surgery of Healthcare Ministry of Russia, Moscow, Russia.

Aim: To present single-center experience and results of surgical treatment of acquired tracheal stenosis.

Material And Methods: There were 99 patients with acquired tracheal stenosis for the period from January 2008 to December 2017. Median age was 39 (28; 55) years (range 19-79 years), male/female ratio - 64/35. Read More

Ann Thorac Surg 2019 Mar 5. Epub 2019 Mar 5.

Departments of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan. Electronic address:

Background: Slide tracheoplasty is the preferred approach for treating long-segment congenital tracheal stenosis (CTS). However, little research has been conducted on the tracheobronchial anatomy before and after slide tracheoplasties in patients with CTS.

Methods: We reviewed 23 patients with CTS who received slide tracheoplasties. Read More

Oncologist 2019 Mar 6. Epub 2019 Mar 6.

Division of Hematology/Oncology, Georgetown Lombardi Comprehensive Cancer Center, MedStar Georgetown University Medical Center, Washington, D.C., USA.

Background: Juvenile-onset recurrent respiratory papillomatosis (JO-RRP) is a human papilloma virus-mediated progressive benign neoplasm that affects children and young adults. Primary management consists of regular surgical debulking to maintain airway patency and vocal function. Like condyloma acuminata, JO-RRP is associated with immune dysregulation, and T cells isolated from papillomas express an anergic phenotype. Read More

J Cardiothorac Surg 2019 Mar 1;14(1):49. Epub 2019 Mar 1.

Department of Thoracic Surgery, Choray Hospital, Nguyen Chi Thanh street, District No. 5, Hochiminh City, Vietnam.

Background: Congenital tracheal malformations are less common than congenital cardiac diseases and surgical repair of these anomalies is complex. We sought to examine the surgical treatment and outcomes in cases of tracheal anomalies presenting with or without associated congenital malformations.

Methods: We retrospectively reviewed the demographic, clinical, and imaging data of 49 children who underwent surgery for congenital tracheal malformations between August 2013 and September 2017. Read More

Anat Rec (Hoboken) 2019 Feb 26. Epub 2019 Feb 26.

Department of Otolaryngology, Head and Neck Surgery, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

The tracheal lumen is essential for conducting air to the lung alveoli and for voice production. However, patients with severe tracheal stenosis and malignant tumors invading the trachea often require tracheal resection. Recently, various reported tissue engineering methods for tracheal reconstruction show that regeneration of ciliated epithelium in the reconstructed areas, as well as preservation of the luminal structure is possible. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Feb;33(2):176-178

Arch Bronconeumol 2019 Feb 20. Epub 2019 Feb 20.

Servicio de Neumología, Hospital Universitario Puerta del Mar, Cádiz, España.

Eur Arch Otorhinolaryngol 2019 Mar 22;276(3):785-792. Epub 2019 Feb 22.

Department of Otorhinolaryngology Head and Neck Surgery, Katharinenhospital, Kriegsbergstrasse 60, 70174, Stuttgart, Germany.

Purpose: The European Laryngological Society (ELS) has published a revised classification for benign laryngotracheal stenosis (LTS), based on their degree, longitudinal extension, and associated comorbidities. We retrospectively applied this classification to pediatric patients treated in four referral centers to assess its reliability in predicting surgical outcomes.

Methods: We included 191 pediatric LTS patients treated by segmental resection, restaged according to the degree of stenosis (I-IV according to Myer-Cotton grading system), number of subsites involved ("a" to "d" for 1-4 subsites among supraglottis, glottis, subglottis and trachea), and presence of systemic comorbidity ("+" sign). Read More

J Tissue Eng Regen Med 2019 Apr 1;13(4):694-703. Epub 2019 Apr 1.

Department of Cardiothoracic Surgery, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Traditional treatment therapies for tracheal stenosis often cause severe post-operative complications. To solve the current difficulties, novel and more suitable long-term treatments are needed. A whole-segment tissue-engineered trachea (TET) representing the native goat trachea was 3D printed using a poly(caprolactone) (PCL) scaffold engineered with autologous auricular cartilage cells. Read More

J Vasc Bras 2018 Oct-Dec;17(4):348-352

Faculdade de Ciências Médicas e da Saúde de Juiz de Fora - SUPREMA, Juiz de Fora, MG, Brasil.

Tracheo-innominate artery fistula (TIF) is a rare complication of tracheostomy, with incidence ranging from 0.1 to 1%, but mortality is high in untreated cases. Early signs range from self-limited bleeding to massive hemorrhage with hypovolemic shock. Read More

Lasers Med Sci 2019 Feb 14. Epub 2019 Feb 14.

Division of Thoracic Surgery, Thoracic Surgery Research Laboratory (LIM-61), Heart Institute (InCor) do Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Rua Dr. Eneas de Carvalho Aguiar 44, Bloco I, 7° andar, São Paulo, SP, 05403-000, Brazil.

To evaluate the feasibility of a 980-nm contact diode laser (CDL) as a method for creating a posterior laryngofissure in live pigs. Twenty-eight Landrace pigs (15-20 kg) were anesthetized, intubated, ventilated, and submitted to a cervical tracheostomy. An anterior and posterior midline longitudinal laryngofissure incision was created according to randomization-control (n = 4), posterior laryngofissure with a scalpel blade; electrocautery (n = 12), posterior laryngofissure by electrocautery (10, 15, 20, 25 W powers); CDL (n = 12), posterior laryngofissure by the CDL (10, 15, 20, 25 W peak powers in pulsed mode). Read More

Thorac Cardiovasc Surg 2019 Feb 11. Epub 2019 Feb 11.

Department of Pediatric Cardiac Surgery, Heart Hospital, G. Monasterio Foundation, Massa, Italy.

Background:  Left pulmonary artery (LPA) sling (PAS) is a vascular ring, which is frequently associated with long-segment tracheal stenosis (TS). Mortality rate in operated children is still high, especially in cases of severe tracheal hypoplasia and/or associated congenital heart defects (CHDs). We report our experience of treatment and follow-up in a pediatric cohort of patients affected by PAS with severe tracheobronchial involvement. Read More

Ann Thorac Surg 2019 Feb 7. Epub 2019 Feb 7.

Department of Thoracic Surgery, University of Perugia Medical School, Loc. Sant'Andrea delle Fratte, 06134, Perugia, Italy. Electronic address:

An innovative technique for airway management, utilizing a small diameter, short-cuffed, orotracheal tube for assisting rigid bronchoscopy in critical airway obstruction is reported. The device, part of Translaryngeal Tracheostomy KIT, was placed beyond the stenosis and used in combination with the rigid bronchoscope. This procedure improves safety during the management of critical tracheal stenoses, because the airway is constantly under the anesthesiologist's control. Read More

J Bras Pneumol 2018 Nov-Dec;44(6):486-490

. Departamento de Cirurgia, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista - UNESP - Botucatu (SP) Brasil.

Objective: To evaluate the efficacy of mitomycin C (MMC) in the endoscopic treatment of tracheal stenosis.

Methods: Patients with laryngotracheal, tracheal, or tracheobronchial stenosis were treated with dilation and topical MMC. The inclusion criteria were as follows: being ineligible for surgery (for medical reasons) at the time of evaluation; membranous stenosis responding well to dilation; and postoperative stenosis at the anastomosis site. Read More

Birth Defects Res 2019 Mar 4;111(5):237-247. Epub 2019 Feb 4.

Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah.

Background: The mutant chondrodysplasia (cho) is a cartilage-targeting disorder in C57BL mice that results in dwarfing and other malformations stemming from this collagenopathy. Clarke Fraser made the discovery of the mutation accidentally in the early 1960s during the thalidomide tragedy.

Methods: For this review we identified key research on cho as since its discovery. Read More

Otolaryngol Head Neck Surg 2019 Feb 5:194599818825471. Epub 2019 Feb 5.

2 Surgical Outcomes Center for Kids, Vanderbilt University, Nashville, Tennessee, USA.

Objective: The primary aim of this study is to evaluate the safety, efficacy, and execution of major open laryngotracheal operations for patients in the advanced decades.

Study Design: Case series with chart review.

Setting: Multidisciplinary clinic at a tertiary care academic hospital. Read More

Eur J Cardiothorac Surg 2019 Jan 31. Epub 2019 Jan 31.

Department of Cardiac Surgery, Royal Children's Hospital, Melbourne, Australia.

Objectives: Pulmonary artery (PA) sling is a rare vascular anomaly often associated with congenital tracheal stenosis. We describe the long-term outcomes with repair of this condition.

Methods: A retrospective study was conducted at 2 institutions. Read More

Intern Med 2019 Feb 1. Epub 2019 Feb 1.

Department of Respiratory Medicine, National Hospital Organization Tokyo Medical Center, Japan.

Pulmonary artery (PA) sling is a congenital disease in which the left PA abnormally arises from the right PA and is usually diagnosed during the infantile period. We present an adult case of PA sling accompanied by tracheobronchomalacia found in a 49-year-old woman with a history of recurrent pneumonia. Computed tomography of the chest showed that the left lung was nourished by two aberrant PAs. Read More

Thorax 2019 Apr 2;74(4):419-420. Epub 2019 Feb 2.

Department of Clinical Radiology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.

Pneumologie 2019 Apr 31;73(4):211-218. Epub 2019 Jan 31.

Lungenklinik Köln-Merheim, Lehrstuhl für Thoraxchirurgie, Kliniken der Stadt Köln gGmbH, private Universität Witten/Herdecke, Köln.

Introduction:  Cervical stenosis of the trachea caused by tracheotomy, tumor or without defined reason (idiopathic) can be treated by resection and anastomosis with good early and long-term results. Involvement of the ring cartilage makes the procedure technically demanding and increases the risk of morbidity. We describe our technique of laryngotracheal resection and reconstruction and compare the perioperative results with standard tracheal resection. Read More

Ann Otol Rhinol Laryngol 2019 May 30;128(5):391-400. Epub 2019 Jan 30.

1 Center for Regenerative Medicine, Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.

Objectives: The clinical experience with tissue-engineered tracheal grafts (TETGs) has been fraught with graft stenosis and delayed epithelialization. A mouse model of orthotopic replacement that recapitulates the clinical findings would facilitate the study of the cellular and molecular mechanisms underlying graft stenosis.

Methods: Electrospun nanofiber tracheal scaffolds were created using nonresorbable (polyethylene terephthalate + polyurethane) and co-electrospun resorbable (polylactide-co-caprolactone/polyglycolic acid) polymers (n = 10/group). Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):2241-2243

Dept. of Surgery, Kansai Rosai Hospital.

Background: Airway invasion due to inoperable advanced esophageal cancers can sometimes cause serious complications includingairway stenosis and fistula, and compromise patients' QOL. We retrospectively evaluated the effect of tracheobronchial airway stentingfor airway stenosis due to inoperable advanced esophageal cancers.

Methods: Between 2010 and 2017, 9 patients with airway stenosis due to inoperable advanced esophageal cancers were treated by placement of a tracheo- bronchial airway stent. Read More

Rev Mal Respir 2019 Jan 25. Epub 2019 Jan 25.

Service de chirurgie thoracique, CHU Hassan II, BP. 1893, Km 2.200, route de Sidi Harazem, 30000 Fès, Maroc; Faculté de médecine et de pharmacie, université Sidi Mohamed Ben Abdellah, Fès, Maroc.

Introduction: Primary tumours of the trachea are very rare and may develop from the tracheal salivary glands.

Case Reports: We describe four patients operated on in our service between 2010 and 2017 of whom two had an adenocystic carcinoma, one a mucoepidermoid carcinoma and one a pleomorphic adenoma of the trachea. All were treated by resection and tracheal anastomosis with clear margins in three cases. Read More

Ann Otol Rhinol Laryngol 2019 May 28;128(5):453-459. Epub 2019 Jan 28.

1 Department of Otolaryngology-Head & Neck Surgery, The Ohio State University Medical Center, Columbus, OH, USA.

Objectives: Laryngotracheal stenosis and obstruction can be challenging to manage. Traditional assessment tools are limited in clinical correlation. Three-dimensional computational fluid dynamics (CFD) modeling is a novel technique used to analyze airflow dynamics. Read More

Niger J Clin Pract 2019 Jan;22(1):134-137

Division of Cardiothoracic Surgery, National Cardiothoracic Center, University of Nigeria Teaching Hospital, Enugu, Nigeria.

Postintubation tracheal stenosis (PITS) is a known complication of endotracheal intubation or tracheostomy. It is the most common indication for tracheal resection/reconstructive surgery. Despite technological improvement and skilled patient care in the ICU, PITS still constitutes an important group of iatrogenic sequela after intubation. Read More

Medicine (Baltimore) 2019 Jan;98(3):e14169

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University.

We aimed to evaluate the safety and efficacy of combined airway and esophageal stents under fluoroscopy guidance and local anesthesia for patients with malignant tracheobronchial and esophageal disease. This retrospective analysis included 35 consecutive patients underwent combined stenting from March 2012 to August 2016. All patients underwent chest computed tomography scans before stenting and during follow-up. Read More

J Dent Anesth Pain Med 2018 Dec 28;18(6):375-378. Epub 2018 Dec 28.

Department of Dental Anesthesia and Pain Medicine, School of Dentistry, Pusan National University, Dental Research Institute, Yangsan, Republic of Korea.

Endotracheal intubation is commonly associated with laryngeal injury that often resolves spontaneously without any complication. However, stenosis or granulomatous lesions are generally found on the tracheal wall or vocal process at the tube cuff level, caused by excessive cuff pressure. We present a case of fatal vocal cord granuloma leading to dyspnea following orthognathic surgery and sustained intubation for 14 hours. Read More

Zhonghua Kou Qiang Yi Xue Za Zhi 2019 Jan;54(1):23-28

Department of General Surgery, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.

To discuss the surgical safeness of the cleft palate children with airway stenosis by means of analyzing characteristics of the shape of the upper airway and comparing clinical data of cleft palate children with airway stenosis and non-airway stenosis. Tracing back from Apirl 2015 to Apirl 2017, 126 cleft palate children treated in Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, were included (46 male and 80 female, age of 7 to 74 months, median age 18 months). According to the spiral CT scan of neck, patients were categorized to airway-stenosis group (65 patients) and non-airway-stenosis group (61 patients). Read More

Laryngoscope 2019 Jan 8. Epub 2019 Jan 8.

Institute of Cellular Medicine, Newcastle upon Tyne, United Kingdom.

Objective: Translational research into subglottic disease is restricted by the availability of primary human tissue originating from this subsite. Primary epithelial cells are also limited by their inability to survive beyond several divisions in culture outside of the body. Specific subglottic cell lines, useful for in vitro studies, have not yet been described. Read More

Front Pediatr 2018 18;6:401. Epub 2018 Dec 18.

Neonatal Surgery Unit, Department of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital, Rome, Italy.

Presence of laryngotracheal abnormalities is associated with increased morbidity and higher mortality rate in esophageal atresia patients. Determine the prevalence of laryngotracheal abnormalities (LTA) in a prospectively collected cohort of patients treated for esophageal atresia and/or tracheoesophageal fistula (EA/TEF). Analysis of the impact of those airway anomalies in early post-operative outcomes was performed. Read More

Int J Artif Organs 2019 Jan 7:391398818819953. Epub 2019 Jan 7.

1 National Research Center for Maternal and Child Health, Astana, Kazakhstan.

Purpose:: For the first time in Kazakhstan, we have used a combined extracorporeal support, by including the CytoSorb system in a continuous veno-venous hemofiltration system in an 8-month-old patient with a body weight of 5600 g.

Results:: The CytoSorb therapy session resulted in a reduction of inflammation markers IL-6, S100, procalcitonin, and C-reactive protein. Simultaneously, the level of transaminases, creatine kinase, and troponin were normalized, by the end of the session patient hemodynamics were stable and there was no need for vasopressors, acid-base balance was maintained, and the patient was weaned from mechanical ventilation to spontaneous breathing. Read More

Ann Otol Rhinol Laryngol 2019 Apr 4;128(4):293-299. Epub 2019 Jan 4.

1 University Voice and Swallowing Center, Department of Otolaryngology-Head and Neck Surgery, UC Irvine School of Medicine, Irvine, CA, USA.

Objective:: Idiopathic subglottic stenosis (iSGS) is a rare disease with few local resources for individuals to use. With the explosive growth of online social networking, platforms such as Facebook possess compelling potential to facilitate user-driven sharing of health information and peer support. This study was performed to better understand the content shared in a busy online community for individuals with iSGS. Read More

Thorac Cancer 2019 Feb 29;10(2):378-380. Epub 2018 Dec 29.

Department of Thoracic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.

Robotic surgery for circumferential tracheal resection and reconstruction has not previously been reported. Herein we describe the case of a 48-year-old man with primary extra-luminal tracheal leiomyosarcoma. A preoperative bronchoscopy exam and chest computed tomography revealed a tracheal neoplasm, which derived from lower membranous trachea and nearly obstructed the orifice of the left main bronchus. Read More

Laryngoscope 2019 Apr 28;129(4):818-822. Epub 2018 Dec 28.

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, U.S.A.

Objectives: 1) Evaluate success rates for adults undergoing cervical slide tracheoplasty. 2) Examine complication rates of slide tracheoplasty in adults.

Methods: A retrospective cohort of adults > 21 years of age undergoing cervical slide tracheoplasty for tracheal stenosis between October 2011 and August 2017 was reviewed. Read More