8,392 results match your criteria Trabeculectomy

Gonioscopy Assisted Transluminal Trabeculotomy:A Boon to Developing Nations-A Systematic Review.

Semin Ophthalmol 2022 Jul 1:1-5. Epub 2022 Jul 1.

Glaucoma Services, L V Prasad Eye Institute, Visakhapatnam, India.

Purpose: To systematically review surgical procedure, safety and efficacy of Gonioscopy-Assisted Transluminal Trabeculotomy (GATT).

Methods: A review of literature was done to analyze all suitable articles from two different databases.

Results: GATT is effective in reducing intraocular pressure and mean number of medications from baseline. Read More

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Glaucoma management in congenital ectropion uveae: Surgical outcomes from a large tertiary referral center in South India.

Eur J Ophthalmol 2022 Jun 29:11206721221111595. Epub 2022 Jun 29.

Meera and L B Deshpande Centre for Sight Enhancement, Institute for Vision Rehabilitation, Hyderabad, Telangana, India.

Purpose: To evaluate the long-term outcomes of glaucoma management in patients with congenital ectropion uveae (CEU) over a period of three decades at a single large referral tertiary eye care center.

Methods: Retrospective chart review of all patients with CEU treated surgically from 1990 to 2019 was performed. Primary combined trabeculotomy-trabeculectomy (CTT), trabeculectomy with and without mitomycin-C (MMC) (0. Read More

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Femtosecond Laser-assisted Cataract Surgery in Patients With Prior Glaucoma Surgery.

J Glaucoma 2022 Jul 7;31(7):547-556. Epub 2022 Apr 7.

Montreal Glaucoma Institute and Bellevue Ophthalmology Clinics.

Prcis: Femtosecond laser-assisted cataract surgery (FLACS) is a safe procedure in glaucomatous eyes with prior glaucoma surgery, evidenced by stable intraocular pressure (IOP) and medication use, acceptable success rate, disease stability, and low complication rates at 1-year postoperative.

Purpose: The purpose of this study was to assess the 1-year efficacy and safety of FLACS in glaucomatous eyes with prior glaucoma surgery.

Materials And Methods: Retrospective case series of all consecutive glaucomatous eyes with previous glaucoma surgery that underwent FLACS using the Catalys Precision Laser System with or without concomitant glaucoma surgery at a single ophthalmology center, between 2014 and 2020. Read More

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Deadbolt cataract due to misplanted minishunt.


J Cataract Refract Surg 2022 07;48(7):863

A 62-year-old woman with stable unilateral glaucoma in the left eye presented for a cataract consultation. In 2010, laser peripheral iridotomies (LPI) were performed on both eyes by a different provider. Her postoperative course was complicated by a recalcitrant steroid response with a highest intraocular pressure (IOP) of 65 mm Hg in the left eye. Read More

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Predictability of combined cataract surgery and trabeculectomy using Barrett Universal Ⅱ formula.

PLoS One 2022 23;17(6):e0270363. Epub 2022 Jun 23.

Department of Ophthalmology, Kitasato University, Sagamihara, Japan.

Purpose: To compare the predictability of intraocular lens (IOL) power calculation using the Barrett Universal II and the SRK/T formulas in eyes undergoing combined cataract surgery and trabeculectomy.

Methods: We retrospectively reviewed the clinical charts of 56 consecutive eyes undergoing cataract surgery and trabeculectomy. IOL power calculations were performed using the Barrett Universal II and SRK/T formulas. Read More

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Trabeculopuncture as a predictive test of distal outflow resistance in canal-based surgery.

Sci Rep 2022 Jun 22;12(1):10584. Epub 2022 Jun 22.

Department of Ophthalmology, University of Würzburg, Würzburg, Germany.

We investigated whether trabeculopuncture (TP) could detect distal outflow resistance to predict the outcome of canal-based glaucoma surgery such as ab interno trabeculectomy (AIT). These procedures have a high utilization in open angle glaucoma, but fail in eyes with an unidentified distal outflow resistance. We assigned 81 porcine eyes to two groups: trial (n = 42) and control (n = 39). Read More

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Effect of pigmentation intensity of trabecular meshwork cells on mechanisms of micropulse laser trabeculoplasty.

Sci Rep 2022 Jun 22;12(1):10535. Epub 2022 Jun 22.

Department of Ophthalmology, Graduate School of Medicine, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

The intraocular pressure (IOP)-lowering mechanisms of micropulse laser trabeculoplasty (MLT) remain unclear. The present study was performed to investigate the mechanism of action of MLT, and to determine whether the pigmentation intensity of trabecular meshwork (TM) cells is associated with the treatment effects. Primary human TM cells were exposed to melanin granules to artificially introduce different levels of pigmentation. Read More

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Recurrent macular neurosensory detachment in hypotony maculopathy managed with topical corticosteroids.

BMJ Case Rep 2022 Jun 15;15(6). Epub 2022 Jun 15.

Department of Ophthalmology, Hospital Pedro Hispano, Matosinhos, Porto, Portugal.

A female patient in her late 70s underwent uncomplicated non-penetrating deep sclerectomy surgery. Three years after surgery, she presented with a sudden decrease in visual acuity, intraocular pressure (IOP) of 2 mmHg, macular folding and significant macular subretinal fluid. Assuming hypotony as the cause, topical dexamethasone was started, with complete functional and imagological improvement. Read More

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Short-term Efficacy and Safety of Open Conjunctiva ab Externo XEN45 Gel Stent Implantation in Glaucoma Patients.

J Glaucoma 2022 Jun 14. Epub 2022 Jun 14.

Division of Ophthalmology - Department of Surgery, University of Saskatchewan.

Prcis: We examined the safety and efficacy of the open conjunctiva ab externo approach for XEN45 gel stent implantation. There was a significant reduction in intraocular pressure and number of glaucoma medications at 12 months follow-up.

Purpose: This study aims to determine the safety and efficacy of the open conjunctiva ab externo approach to XEN45 stent implantation. Read More

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Proportion of Glaucoma Types and Surgeries Among Young, Pre-Old, Old, and Oldest-Old Age Groups or Different Sex Groups.

Clin Ophthalmol 2022 7;16:1815-1819. Epub 2022 Jun 7.

Division of Ophthalmology, Matsue Red Cross Hospital, Matsue, Shimane, Japan.

Background: We report the real-world distribution of glaucoma types and glaucoma surgeries in each age or sex group in our department.

Methods: The department database of Matsue Red Cross Hospital, a tertiary care hospital, for eyes surgically treated to manage glaucoma between April 2014 and March 2018 was searched. Patient age, sex, disease type, and surgical procedure were collected from the database. Read More

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Waveform changes of laser speckle flowgraphy in the temporal optic nerve head and peripapillary atrophy after trabeculectomy in open-angle glaucoma.

Sci Rep 2022 Jun 13;12(1):9802. Epub 2022 Jun 13.

Department of Ophthalmology, Kanazawa University Graduate School of Medical Sciences, Takara-mach13-1, Kanazawa, Ishikawa-ken, 920-8641, Japan.

A prospective study was conducted on 33 eyes of 33 patients with open-angle glaucoma who underwent trabeculectomy to investigate hemodynamic changes in the temporal optic nerve head (ONH) and peripapillary atrophy (PPA) after trabeculectomy. Laser speckle flowgraphy of ONH and PPA was performed at baseline and at 1, 3, and 6 months postoperatively. The waveforms of the mean blur rate in the tissue area (MT) in the temporal ONH, βPPA (with Bruch's membrane), and γPPA (without Bruch's membrane) were evaluated. Read More

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Risk of surgical failure and hemorrhagic complications associated with antithrombotic medication in glaucoma surgery.

Graefes Arch Clin Exp Ophthalmol 2022 Jun 10. Epub 2022 Jun 10.

Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.

Purpose: The purpose of this retrospective study was to determine the extent to which the use of antithrombotic drugs during glaucoma surgery contributes to surgical failure and postsurgical hemorrhagic complications.

Methods: Glaucoma surgeries were categorized into three groups: trabeculotomy (TLO), trabeculectomy (TLE), and long-Tube shunt surgery (Tube). At 1 year after surgery, the following criteria for surgical success were met: intraocular pressure (IOP) in the 5-21-mmHg range, IOP reduction of at least 20% from the preoperative level, and no additional glaucoma surgeries. Read More

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Micropulse laser trabeculoplasty on Chinese patients with glaucoma or ocular hypertension: average 35 months follow-up results.

BMC Ophthalmol 2022 Jun 4;22(1):249. Epub 2022 Jun 4.

Department of Ophthalmology, Second Xiangya Hospital, Central South University, Hunan, 410011, China.

Background: Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss. A novel technology micropulse laser trabeculoplasty (MLT) can use duty-circle subvisible laser pulses to treat glaucoma. The aim of this study is to evaluate the efficacy of 360° MLT to alleviate intraocular pressure (IOP) in patients with glaucoma. Read More

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Comparison of Outcomes from Delayed Onset Bleb-related Endophthalmitis Treated with Pars Plana Vitrectomy versus Vitreous Biopsy.

J Glaucoma 2022 Jun 2. Epub 2022 Jun 2.

The Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Palm Beach Gardens, FL.

Prcis: Bleb-related endophthalmitis is a serious complication of glaucoma filtration surgery. The current study reports similar visual and intraocular pressure outcomes in eyes treated with pars plana vitrectomy compared to vitreous biopsy and intravitreal antibiotics.

Purpose: To investigate the isolated organisms, visual acuity (VA) and intraocular pressure (IOP) outcomes associated with delayed-onset bleb-related endophthalmitis (BRE) in eyes treated with pars plana vitrectomy (PPV) versus vitreous biopsy and injection of intravitreal antibiotics (TI). Read More

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Modified Trabeculectomy versus Glaucoma Drainage Implant Surgery: A Retrospective Comparative Study for Refractory Glaucoma Treatment.

Oxid Med Cell Longev 2022 23;2022:3050007. Epub 2022 May 23.

Department of Ophthalmology, Xianyang First People's Hospital, Baoji, 712099 Shaanxi Province, China.

Purpose: To observe and compare the efficacy of modified trabeculectomy (TE), Ahmed drainage valve implantation (AGV), and EX-PRESS glaucoma shunt for refractory glaucoma (RG).

Methods: The study population of this retrospective study comprised 73 patients (76 eyes) who were suffering from RG and treated with modified TE, AGV, and EX-PRESS glaucoma shunt in our hospital from October 2012 to October 2020. The number of cases who underwent modified TE, AVG, and EX-PRESS glaucoma shunt was 36 (38 eyes). Read More

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Surgical Advancement of Tenon's Layer During Trabeculectomy Improves Bleb Morphology.

J Glaucoma 2022 Jun 6;31(6):e32-e36. Epub 2022 Apr 6.

Department of Ophthalmology, Mayo Clinic, Rochester, MN.

Trabeculectomy surgery remains the gold standard incisional glaucoma surgical procedure in many practices, particularly for patients requiring intraocular pressure (IOP) in the low teens or below. However, trabeculectomy surgery is associated with complications including leakage, over filtration, or fibrosis of the surgical bleb. Morphology of the surgical bleb is an important predictor of surgical success defined as long-term IOP reduction with minimal to no complications. Read More

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Insertion of a Preserflo microshunt inside a non-valved glaucoma shunt to treat late-onset hypotony.

Indian J Ophthalmol 2022 Jun;70(6):2180-2182

Department of Ophthalmology, Queens Medical Centre, Lenton, Nottingham, United Kingdom.

We present a case of advanced glaucoma with previously failed trabeculectomy who underwent a Baerveldt tube (BVT) insertion, with initial success. However, 9 months post BVT insertion he developed profound clinically significant hypotony. Two attempts at controlling this with suture exchange led to episodes of significant ocular hypertension, followed by hypotony each time. Read More

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Commentary: Needle goniotomy in adults: Is it a viable minimally-invasive glaucoma surgery option?

Indian J Ophthalmol 2022 Jun;70(6):2036-2037

Department of Glaucoma, Centre for Sight, Hyderabad, Telangana, India.

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Six-month outcomes of combined conventional needle goniotomy and phacoemulsification in eyes with early to moderate primary open-angle and pseudoexfoliation glaucoma and ocular hypertension.

Indian J Ophthalmol 2022 Jun;70(6):2030-2035

Glaucoma Service, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Purpose: Angle-based surgeries for the treatment of open-angle glaucoma have gained popularity in recent years. This study aimed to evaluate the efficacy of combined phacoemulsification and goniotomy in primary open-angle and pseudoexfoliation glaucoma (POAG and PXG) and ocular hypertension (OHTN).

Methods: In this interventional case series in the setting of the Glaucoma Service at the Farabi Eye Hospital, 32 eyes of 30 patients with early-to-moderate POAG and PXG and OHTN were enrolled. Read More

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The Norwich trabeculectomy study: risk factor analysis for the development of adverse, thin cystic blebs.

Acta Ophthalmol 2022 May 30. Epub 2022 May 30.

Norfolk & Norwich University Hospital NHS Foundation Trust, Norwich, UK.

Purpose: To investigate potential risk factors, particularly antimetabolite choice, with regard to the development of adverse bleb morphology in eyes that had undergone trabeculectomy surgery.

Methods: A single-centre, observational cohort study of 631 consecutive eyes, which had undergone trabeculectomy over an 11-year period. For each case, bleb morphology was recorded at 2 years, and its association with the per-operative antimetabolite as well as potential confounding risk factors was analysed using univariate (unadjusted) and multivariate (adjusted) logistical regression analyses to identify those that could contribute to the development of adverse blebs. Read More

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Atypical morgagnian cataract. Case report.

Cir Cir 2022 ;90(3):414-418

Departamento de Segmento Anterior, Fundación Hospital Nuestra Señora de la Luz, IAP, Ciudad de México, México.

Objective: Describe an atypical case of a morgagnian cataract with diffusion of cortical material through the intact posterior capsule.

Clinical Case: 50-year-old male, with 24 hours of evolution, referring pain, photophobia, and seven year history of visual loss. Intraocular pressure of 36 mmHg, opaque cornea, anterior chamber with a whitish material, liquefied crystalline cortex. Read More

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Comparative cost-effectiveness of trabeculectomy versus MicroShunt in the United States Medicare system.

Ophthalmology 2022 May 27. Epub 2022 May 27.

Department of Ophthalmology and Visual Sciences, University of Alabama at Birmingham (UAB) Callahan Eye Hospital, Birmingham, AL, United States.

Purpose: To assess the societal cost-utility of MicroShunt compared with trabeculectomy for the surgical management of glaucoma in the United States Medicare system.

Design: Cost-utility analysis using efficacy and safety results of a randomized controlled trial and other pivotal clinical trials.

Subjects: Markov model cohort of patients with open angle glaucoma METHODS: Open angle glaucoma treatment costs and effects were analysed with a deterministic model over a 1-year horizon using TreeAge software. Read More

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Subtenon triamcinolone as an adjuvant in mitomycin-C-enhanced trabeculectomy in non-inflammatory glaucomas: A randomized clinical trial.

PLoS One 2022 26;17(5):e0268623. Epub 2022 May 26.

Department of Ophthalmology, Federal University of São Paulo, São Paulo, São Paulo, Brazil.

This unicentric randomized clinical trial was designed to compare the surgical outcomes of mitomycin C-enhanced trabeculectomy (MMC-TRAB) with and without subtenon triamcinolone acetonide (TAAC) injection in patients with non-inflammatory glaucomas. This trial is registered at the Brazilian Registry of Clinical Trials (ReBEC) under the register number RBR-53f8nh. Consecutive non-inflammatory glaucoma patients requiring surgical intervention were randomized into two groups. Read More

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Refractory Childhood Glaucoma Secondary to Weill-Marchesani Syndrome. Case Management with Combined CO Laser-Assisted Sclerectomy Surgery and Trabeculectomy.

Chin Med Sci J 2022 May 16. Epub 2022 May 16.

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100730, China.

A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature, short and stubby hands and feet,language disorders and mental retardation, who developed bilateral angle closure glaucoma, ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani syndrome. The child was successfully treated by combined CO laser-assisted sclerectomy surgery and trabeculectomy. Read More

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Comparisons of the short-term effectiveness and safety of surgical treatment for neovascular glaucoma: a systematic review and network meta-analysis.

BMJ Open 2022 05 24;12(5):e051794. Epub 2022 May 24.

Shenzhen Eye Institute, Shenzhen Eye Hospital, Shenzhen, Guangdong Province, China

Objective: To compare the effectiveness and safety of the six interventions for neovascular glaucoma.

Design: A systematic review and network meta-analysis.

Methods: Randomised controlled trials and cohort studies which compared the six interventions in neovascular glaucoma were identified using the following databases searched up to 1 September 2020: PubMed, Cochrane Library, Embase and Web of Science. Read More

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Cystoid Macular Edema after an uncomplicated Gonioscopy- Assisted Transluminal Trabeculotomy on a previously vitrec- tomized patient.

Clin Ter 2022 May;173(3):198-202

Clinica Oftalmológica Paredes, Pasto, Nariño, Colombia.

Purpose: The main purpose of this study was to report a case of cystoid macular edema (CME) after gonioscopy-assisted transluminal trabeculotomy (GATT).

Methods: We describe the case of a 73-year-old woman with ocular hypertension and history of cataract surgery combined with posterior vitrectomy and epiretinal membrane peeling 2 years before, who developed CME after uncomplicated GATT procedure.

Results: Uneventful GATT surgery was performed in an eye with ocular hypertension. Read More

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Two Cases of Consecutive Toxic Anterior Segment Syndrome after Uneventful Trabeculectomy Surgeries in a Tertiary Center.

Case Rep Ophthalmol 2022 Jan-Apr;13(1):234-242. Epub 2022 Apr 4.

Unidad Oftalmológica de Caracas, Fundación AVAO, Caracas, Venezuela.

Toxic anterior segment syndrome (TASS) is a severe, acute, sterile intraocular inflammation that occurs the same day or in the early stages after intraocular surgery. It has been most commonly reported after phacoemulsification. We report 2 cases that developed TASS after sequential uneventful trabeculectomy surgeries, in which a quaternary ammonium compound was used for the disinfection of surgical instruments. Read More

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Reduced Intraocular Pressure Variability after Gonioscopy-Assisted Transluminal Trabeculotomy Procedure.

Ophthalmol Glaucoma 2022 May-Jun;5(3):336

Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, Maryland.

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Elucidating the Therapeutic Potential of Cell-Penetrating Peptides in Human Tenon Fibroblast Cells.

ACS Omega 2022 May 3;7(19):16536-16546. Epub 2022 May 3.

Department of Nanobiotechnology, Vision Research Foundation, No.18/41, College Road, Nungambakkam, Chennai, Tamil Nadu 600006, India.

Cell-penetrating peptides (CPPs) have been widely used as vehicles for delivering therapeutic molecules to the site of action. Apart from their delivering potential, the biological effects of CPPs have not been explored in detail. JTS-1 is a CPP that has been reported to have gene delivery functions, although its biological role is yet to be determined. Read More

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Irreversible intraocular pressure elevation as a complication of MIRAgel scleral buckling.

Am J Ophthalmol Case Rep 2022 Sep 13;27:101583. Epub 2022 May 13.

Department of Ophthalmology and Visual Science, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima City, Hiroshima, 734-8551, Japan.

Purpose: To report a case of ocular hypertension due to swelling and degeneration of hydrogel explant (MIRAgel) after retinal detachment surgery.

Observations: The patient who had a history of left retinal detachment 23 years prior had been regularly followed up for epiretinal membrane in the left eye at the Department of Ophthalmology, Hiroshima University Hospital. Two years after the first presentation, the patient had symptoms of foreign body sensation and hyperemia, with elevation of the intraocular pressure (IOP) of the left eye to 24 mmHg. Read More

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September 2022